Digital Commons Network^™

Impacts Of Fire And Prospects For Recovery In A Tropical Peat Forest Ecosystem, Me Harrison, Nj Deere, Ma Imron, D Nasir, Adul, Ha Asti, Ja Soler, Nc Boyd, Sm Cheyne, Sa Collins, Lj D'Arcy, Wm Erb, H Green, W Healy, Hendri, B Holly, Pr Houlihan, Sj Husson, Iwan, Ka Jeffers, Ip Kulu, K Kusin, Nc Marchant, Hc Morrogh-Bernard, Se Page, A Purwanto, Br Capilla, Ord Ortega, Santiano, Kl Spencer

School of Biological and Marine Sciences

Uncontrolled fires place considerable burdens on forest ecosystems, compromising our ability to meet conservation and restoration goals. A poor understanding of the impacts of fire on ecosystems and their biodiversity exacerbates this challenge, particularly in tropical regions where few studies have applied consistent analytical techniques to examine a broad range of ecological impacts over multiyear time frames. We compiled 16 y of data on ecosystem properties (17 variables) and biodiversity (21 variables) from a tropical peatland in Indonesia to assess fire impacts and infer the potential for recovery. Burned forest experienced altered structural and microclimatic conditions, resulting in a proliferation …

Development Of Novel Radiotherapy Treatment Monitoring And Quantitative Cherenkov Surface Dosimetry For Diverse Populations, Savannah M. Decker

Dartmouth College Ph.D Dissertations

In the U.S. alone, nearly 2 million people will be diagnosed with cancer annually, and over half of them will receive radiation therapy throughout the course of their care. While widely regarded as safe, radiation therapy presents unique challenges that other procedures, such as surgery, lack. Namely, the invisible nature of the radiation itself makes it impossible to directly visualize treatment. Many immobilization and localization techniques exist to minimize the chance of incorrect radiation dose delivery, yet incidents still occur. Within the last decade, Cherenkov imaging has emerged as a new radiation therapy delivery verification technique. Cherenkov imaging is unique …

Treating Sex And Gender Differences As A Continuous Variable Can Improve Precision Cancer Treatments, Wei Yang, Joshua B Rubin

2020-Current year OA Pubs

BACKGROUND: The significant sex and gender differences that exist in cancer mechanisms, incidence, and survival, have yet to impact clinical practice. One barrier to translation is that cancer phenotypes cannot be segregated into distinct male versus female categories. Instead, within this convenient but contrived dichotomy, male and female cancer phenotypes are highly overlapping and vary between female- and male- skewed extremes. Thus, sex and gender-specific treatments are unrealistic, and our translational goal should be adaptation of treatment to the variable effects of sex and gender on targetable pathways.

METHODS: To overcome this obstacle, we profiled the similarities in 8370 transcriptomes …

Replication Crisis In Sport And Exercise Science, Zacharias Papadakis, Jennifer Murphy

International Journal of Exercise Science: Conference Proceedings

In Sport and Exercise Science (SES), 82% of published studies report significant findings indicating these studies have a robust research design that examines true effects with high statistical power. However, small sample sizes and underpowered designs are common in SES. Related literature in psychology reports that only 37% of replicated effects yield similar results to the original. Replication studies in SES are still rare, raising concerns about the overwhelming reported significant findings despite the small sample sizes. PURPOSE: To replicate the findings of a published SES study and compare results. METHODS: Based on the criteria published by Murphy …

Non-St Elevation Myocardial Infarction Presentation In Severe Aortic Stenotic Patient, Margi Desai, Daniel Maysonet

The Journal of Integrated Primary Care

This case report demonstrates a patient who presents with typical findings for a diagnosis of NSTEMI. Upon further evaluation, this diagnosis was able to be ruled out. Presentations and labs consistent with NSTEMI masked the true diagnosis of aortic stenosis due to oxygen supply/demand mismatch.

Biopsychosocial Management Of Long Covid Fibromyalgia: Lessons From The Penn Medicine Lancaster General Health Fibromyalgia Program, Joseph Harrison, Dennis Given Psy.D.

The Journal of Integrated Primary Care

The COVID-19 pandemic has increased the prevalence of chronic health concerns worldwide, leading to a new population of patients suffering from Long Covid. Patients with Long Covid often experience persistent symptoms impacting multiple organ systems, including neuroimmune and neurological manifestations. Recently, attention has grown toward Long Covid patients developing chronic widespread pain similar to fibromyalgia. Fibromyalgia is a nociplastic pain disorder characterized by widespread pain and central sensitization with fatigue, sleep disturbances, and impairments in cognitive functioning. Given the nascent and limited research exploring new treatment options, patients need support now from biopsychosocial multi-modal pain management strategies. The Fibromyalgia Program …

24 Conference Program - Ultra-High Temperature Ceramics: Materials For Extreme Environment Applications Vi, Diletta Sciti, Laura Silvestroni, Fréderic Monteverde, Gregory Thompson, Raffaele Savino, Jon Binner, Eric Wuchina

Ultra-High Temperature Ceramics: Materials for Extreme Environment Applications VI

No abstract provided.

The Effects Of Cold-Stored Platelets On Hemorrhagic Patients: A Meta-Narrative Review, Cynthia Y. Medina, Vivian H. Nguyen, Kim T. Pham, Pham T. Vu

Research Methods Poster Session 2024

No abstract provided.

Risk Assessment And Sources Apportionment Of Toxic Metals In Two Commonly Consumed Fishes From A Subtropical Estuarine Wetland System, Md Moudud Ahmed, As-Ad Ujjaman Nur, Salma Sultana, Yeasmin N Jolly, Bilal Ahamad Paray, Takaomi Arai, Jimmy Yu, Mohammad Belal Hossain

Faculty, Staff and Student Publications

The widespread occurrence of heavy metals in aquatic environments, resulting in their bioaccumulation within aquatic organisms like fish, presents potential hazards to human health. This study investigates the concentrations of five toxic heavy metals (Pb, Hg, Zn, Cu, and Cr) and their potential health implications in two economically important fish species (Otolithoides pama and Labeo bata) from a subtropical estuarine wetland system (Feni estuary, Bangladesh). Muscle and gill samples from 36 individual fish were analyzed using energy dispersive X-ray fluorescence (EDXRF). The results revealed that the average quantities of heavy metals in both fishes' muscle followed the declining …

Color On Canvas In Black Britain And Black Germany, Marisa J. Pickett

History ETDs

Using the artwork and poetry of Black artist-activists Lubaina Himid, Keith Piper, May Ayim, and Raja Lubinetzki, a connection was found between the increasingly anti-immigrant rhetoric of conservative politicians of the 1980s and the self-identification and belonging of non-white communities within the countries of Great Britain and Germany. By linking the produced artwork with the direct political initiatives of the time, we are able to draw parallels between the experiences of two diasporic communities, Black Britain and Black Germany, through artists and their work. Artwork can be seen as a medium through which to engage with the audience on a …

Pregnane X Receptor Signaling Pathway And Vitamin K: Molecular Mechanisms And Clinical Relevance In Human Health, Jeff Staudinger, Avina Mahroke, Gauri Patel, Cole Dattel, Sahana Reddy

Faculty and Staff Publications

This review explores the likely clinical impact of Pregnane X Receptor (PXR) activation by vitamin K on human health. PXR, initially recognized as a master regulator of xenobiotic metabolism in liver, emerges as a key regulator influencing intestinal homeostasis, inflammation, oxidative stress, and autophagy. The activation of PXR by vitamin K highlights its role as a potent endogenous and local agonist with diverse clinical implications. Recent research suggests that the vitamin K-mediated activation of PXR highlights this vitamin's potential in addressing pathophysiological conditions by promoting hepatic detoxification, fortifying gut barrier integrity, and controlling pro-inflammatory and apoptotic pathways. PXR activation by …

First-Principles Study Of Electronic Properties Of Substitutionally Doped Monolayer Snp3, Junfeng Jin, Fang Lv, Wei Cao, Ziyu Wang

Faculty, Staff and Student Publications

Isovalent doping offers a method to enhance the thermoelectric properties of semiconductors, yet its influence on the phonon structure and propagation is often overlooked. Here, we take CdX (X=Te, Se) compounds as an example to study the role of isovalent doping in thermoelectrics by first-principles calculations in combination with the Boltzmann transport theory. The electronic and phononic properties of Cd8Se8, Cd8Se7Te, Cd8Te8, and Cd8Te7Se are compared. The results suggest that isovalent doping with CdX significantly improves the thermoelectric performance. Due to the similar properties of Se and Te atoms, the electronic properties remain unaffected. Moreover, doping enhances anharmonic phonon scattering, …

Ensuring Clean Futures: The Vital Role Of Wastewater Treatment, Nadya Casanova

Goal 6: Clean Water and Sanitation

No abstract provided.

Metallic Light-Based Bird-Repellent Prototype To Reduce Paddy Yield Loss In Jatinangor, Sumedang Regency, Ai Siti Santriyani, Ichsan Nurul Bari, Wahyu Daradjat Natawigena, Lindung Tri Puspasari, Syifa Nabilah Subakti-Putri

Jurnal Kultivasi

Munia birds (Lonchura spp.) are pests that attack paddy plants during the reproductive phase. The traditional methods of controlling birds are considered less effective because birds can adapt to the tools used. This study aimed to determine the effectiveness of a metallic light-based bird-repellent prototype to reduce paddy yield loss. The experiment was conducted in Cileles Village paddy fields, Jatinangor Subdistrict, Sumedang Regency, West Java Province, Indonesia. The effectivity of the prototype was tested by measuring the effective distance (m2), counting the frequency of bird visits (number of visits), bird populations, and the level of paddy damage (%), and paddy …

The Effect Of Tryptone And Tomato Juice Addition On The Growth Performance Of Strawberry (Fragaria Ananassa) Explant Under In Vitro Condition, Zulfa Ulinnuha, Etik Wukir Tini, Noor Farid, Dhianing Shalatin

Jurnal Kultivasi

Strawberries are a fruit commodity that has high economic value. The obstacle in strawberry production is the lack of high-quality seed availability with disease-free properties. Tissue culture offers a promising solution to increase both the quantity and quality of strawberry seeds. This study aims to assess the effect of different concentrations of tomato juice and tryptone on the growth of strawberry explants under in vitro growing condition. The research was conducted at the Plant Breeding Laboratory, Faculty of Agriculture, Universitas Jenderal Soedirman, from December 2022 to May 2023. The study employed a Completely Randomized Design (CRD) with two factors. The …

Preparation Of Stevia Extract Used In The Food Industry And Its Antimicrobial Activity, Isomiddin Bobayev, Asaloy Jumaniyozova, Nozima Karimova, Anvar Normatov, Namuna Aliyeva

CHEMISTRY AND CHEMICAL ENGINEERING

A dry extract of the leaves of stevia, belonging to the Asteraceae family, grown in Uzbekistan, was extracted with hot water for use as a sweet flavor additive in the food industry. The content of the extract was determined by thin layer chromatography. The extract turned out to be a mixture of various steviol glycosides. It has been established that the main part of the mass of the extract is steviol glycosides - stevioside, rebaudioside A, rebaudioside C, rebaudioside B. When studying the biological activity of the resulting composition, its antimicrobial activity was determined.

Pickering Emulsions Stabilized By Clay Microparticles And Surfactants, Ayaulym Yertayeva, Akbota Adilbekova, Paul Luckham, Kuanyshbek Musabekov

CHEMISTRY AND CHEMICAL ENGINEERING

The main purpose of this work is to study emulsions stabilized by microparticles of kaolin clay of the Alekseevskoye deposit and bentonite clay of the Tagansky deposit to obtain safe, environmentally friendly and cost-effective stabilizers of natural origin, which can be used for the preparation of cosmetic emulsions. The article shows the oxide composition and mineralogical composition of clays. By analyzing the particle size distribution, the average particle sizes of kaolin and bentonite clays were determined. The effect of nonionic surfactants (Tween 85, Synperionic 13/6), the oil phase (decane, squalane) nature on the stability of the emulsion were studied. Using …

Evaluation Of Alginate Hydrogel Microstrands For Stromal Cell Encapsulation And Maintenance., Sujith Chander Reddy Kollampally, Xulang Zhang, Nicholas Moskwa, Deirdre A Nelson, Susan T Sharfstein, Melinda Larsen, Yubing Xie

Faculty Research 2024

Mesenchymal stromal cells (MSCs) have displayed potential in regenerating organ function due to their anti-fibrotic, anti-inflammatory, and regenerative properties. However, there is a need for delivery systems to enhance MSC retention while maintaining their anti-fibrotic characteristics. This study investigates the feasibility of using alginate hydrogel microstrands as a cell delivery vehicle to maintain MSC viability and phenotype. To accommodate cell implantation needs, we invented a Syringe-in-Syringe approach to reproducibly fabricate microstrands in small numbers with a diameter of around 200 µm and a porous structure, which would allow for transporting nutrients to cells by diffusion. Using murine NIH 3T3 fibroblasts …

Formerly Used Defense Sites On Unalaska Island, Alaska: Mapping A Legacy Of Environmental Pollution, Jennifer Schmidt

ISER Articles

Unalaska Island, Alaska, served as a US military base during World War II. The military installed bases on Unalaska and nearby islands, many of which were built adjacent to Unangan communities. The military used toxic compounds in its operations and left a legacy of pollution that may pose health risks to residents and local wildlife. The goals of this study were to identify hotspots of contamination remaining at Unalaska formerly used defense (FUD) sites, evaluate the risk posed by arsenic, and examine “no US Department of Defense action indicated” (NDAI) status determinations for FUD sites near communities. We compiled soil …

Examining The Relationship Of Cultural Sensitivity, Self-Esteem, And Cultural Identities, Jeanneka Black

Electronic Theses and Dissertations Archive

This study examines qualities of self-esteem and its relationship to the process of self-reflection and sensitivity development. The intercultural sensitivity development model highlights the exploration of cognitive and affective processes as the catalyst for promoting willingness, adaptability, and ongoing curiosity to account for the limitations of present approach to multicultural training. Self-reflection is required to process thoughts and emotions, but self-esteem may serve as the barrier or facilitator of this effort. A moderately positive relationship was found among the total score for intercultural sensitivity and self-esteem. Relationships among the demographic variables of race/ethnicity, sexual orientation, religious/spirituality, age ranges, educational level, …

Chitosan As A Biomedical Material For Additively Manufactured Musculoskeletal Regeneration, Andrew Blass Watson

Electronic Theses and Dissertations Archive

High-energy combat-related extremity injuries to both bone and soft tissue from improvised explosive devices are one of the signature injury patterns suffered by US Servicemen during modern the military engagements. Even with bone healing and adequate management of infection, a significant number of battlefield-injured military personnel have returned from combat with persistent functional deficits. Tissue engineering holds immense promise for regenerative medicine by providing innovative solutions for repairing and replacing damaged tissues. In this study, we present two significant advancements in tissue engineering: the development of a novel bio-ink for muscle tissue constructs and the investigation of drug-loaded membranes for …

Discovery Of Strong 3-Nitro-2-Phenyl-2h-Chromene Analogues As Antitrypanosomal Agents And Inhibitors Of Trypanosoma Cruzi Glucokinase, Shane M. Carey, Destiny M. O’Neill, Garrett B. Conner, Julian Sherman, Ana Rodriguez, Edward L. D'Antonio

Natural Sciences Faculty Publications

Chagas disease is one of the world’s neglected tropical diseases, caused by the human pathogenic protozoan parasite Trypanosoma cruzi. There is currently a lack of effective and tolerable clinically available therapeutics to treat this life-threatening illness and the discovery of modern alternative options is an urgent matter. T. cruzi glucokinase (TcGlcK) is a potential drug target because its product, D-glucose-6-phosphate, serves as a key metabolite in the pentose phosphate pathway, glycolysis, and gluconeogenesis. In 2019, we identified a novel cluster of TcGlcK inhibitors that also exhibited anti-T. cruzi efficacy called the 3-nitro-2-phenyl-2H-chromene analogues. This was achieved by performing a target-based …

Agent-Based Modeling For The Neophyte: An Application Of Netlogo, Olcay Akman, Siddharth Bhumpelli, Christopher Hay-Jahans

Faculty, Staff, and Students

Agent-based modeling has found applications in a wide range of fields including economics, sociology, ecology, epidemiology, transportation planning, and more. Its versatility allows researchers to investigate various “what-if” scenarios, test the effects of different policies or interventions, and gain insights into the underlying mechanisms driving complex systems. This article is intended for the curious student or researcher who is unfamiliar with agentbased modeling and is looking for a quick but reasonably informative exposure to the field.

Compartmental Modeling For The Neophyte: An Application Of Berkeley-Madonna, Olcay Akman, Siddharth Bhumpelli, Cody Cline, Christopher Hay-Jahans

Faculty, Staff, and Students

Compartmental modeling serves as a necessary framework in many fields, especially biomathematics and ecology. This article introduces readers to a user-friendly approach to constructing compartmental models and solving the resulting systems of differential equations to simulate real-world applications. The platform used is Berkeley Madonna, a software package that has an intuitive graphical interface which empowers users—even those with limited mathematical and programming backgrounds—to focus on modeling concepts rather than mathematical or programming intricacies. This makes Berkeley Madonna an ideal platform for students, educators, and researchers.

Chitosan-Based Hydrogels In Drug Delivery, Salma A. Fereig, Mona Mohamed Ahmed Abdelmottaleb

Pharmacy

Hydrogels are three-dimensional cross-linked hydrophilic polymers that are able to absorb large quantities of water and swell. They have various properties like biocompatibility, low toxicity, and mostly biodegradability, which make them attractive for drug delivery applications. Chitosan hydrogels are especially attractive due to the inherent activities of the chitosan itself like the antibacterial, anti-inflammatory, and tissue regeneration enhancement capacity. Therefore, chitosan hydrogels have been proposed for the delivery of various drugs, genes, cytokines, and stem cells via various routes of administration for the treatment of various diseases as well as different forms of degeneration.

Gucy2c Signaling Limits Dopaminergic Neuron Vulnerability To Toxic Insults, Lara Cheslow, Matthew Byrne, Jessica Kopenhaver, Lorraine Iacovitti, Richard Smeyne, Adam Snook, Scott Waldman

Farber Institute for Neuroscience Faculty Papers

Mitochondrial dysfunction and reactive oxygen species (ROS) accumulation within the substantia nigra pars compacta (SNpc) are central drivers of dopaminergic (DA) neuron death in Parkinson's disease (PD). Guanylyl cyclases and their second messenger cyclic (c)GMP support mitochondrial function, protecting against ROS and promoting cell survival in several tissues. However, the role of the guanylyl cyclase-cGMP axis in defining the vulnerability of DA neurons in the SNpc in PD remains unclear, in part due to the challenge of manipulating cGMP levels selectively in midbrain DA neurons. In that context, guanylyl cyclase C (GUCY2C), a receptor primarily expressed by intestinal epithelial cells, …

A Critical Review Of Sociological Research On Sexual Pleasure, Hannah Regan

Faculty Scholarship

Sociologists of sexuality often invoke the theme of pleasure, but it is not always clear what scholars believe the implications and importance of pleasure are. To this end, this paper reviews the existing literature on sexual pleasure, specifically within the field of sociology, to demonstrate what questions about sexual pleasure are (and are not) currently being asked. Through a systematic literature review, I demonstrate that scholars often lack a justification for why pleasure is important. I also connect themes between the kind of questions being asked about pleasure and the justifications attached to these studies, relating to risk mitigation, relationship …

Increasing Multi-Hazard Climate Risk And Financial And Health Impacts On Northern Homeowners, Jennifer Schmidt

ISER Articles

Currently, more than half of the world’s human population lives in urban areas, which are increasingly affected by climate hazards. Little is known about how multi-hazard environments affect people, especially those living in urban areas in northern latitudes. This study surveyed homeowners in Anchorage and Fairbanks, USA, Alaska’s largest urban centers, to measure individual risk perceptions, mitigation response, and damages related to wildfire, surface ice hazards, and permafrost thaw. Up to one third of residents reported being affected by all three hazards, with surface ice hazards being the most widely distributed, related to an estimated $25 million in annual damages. …

Uni Introduction To High School Openscied Workshop [Flier] April 13, 2024, University Of Northern Iowa Science Education Program.

Science Education Update Conference Documents

The flier for the Introduction to High School OpenSciEd Workshop held on April 13, 2024 at the University of Northern Iowa.

Habitat Suitability For Age-0 Lake Sturgeon In The Grand River, Benjamin D. Gunnett

Masters Theses

Lake sturgeon (Acipenser fulvescens) are a state-threatened species in Michigan and have become a focus for conservation. The lower Grand River is home to a remnant population of lake sturgeon between the 6th Street dam in downtown Grand Rapids and Lake Michigan. There has been limited research on age-0 lake sturgeon habitat use in low-gradient and more turbid rivers. To address this deficit, we developed a Habitat Suitability Index (HSI) for age-0 lake sturgeon based on prior literature in the Great Lakes. A HSI combines parameters representing in-stream habitat characteristics to score habitat suitability on a scale of 0-1, 0 …