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Articles 76621 - 76650 of 818784
Full-Text Articles in Entire DC Network
Using Taxonomic And Hybridization Data To Identify Lungless Salamander Kinds, Kayla Natelborg, Adelyn C. Fairley, Timothy R. Brophy
Using Taxonomic And Hybridization Data To Identify Lungless Salamander Kinds, Kayla Natelborg, Adelyn C. Fairley, Timothy R. Brophy
Liberty University Research Week
Baraminology is the study of God’s created kinds as described in Genesis 1. Holobaramins (groups of known organisms sharing continuity and bounded by discontinuity) are scientific approximations of these kinds identified by building up monobaramins (smaller, continuous groups) and dividing apobaramins (larger, discontinuous groups). The lungless salamanders (Caudata: Plethodontidae), composed of over 500 species in 29 genera, have been grouped together by herpetologists for almost 200 years. This consistent taxonomic history suggests that the family represents a cognitum (group of organisms recognized through the human cognitive senses as belonging together) and possibly apobaramin. The goals of the present study are …
Crispr Cas9 Mediated Gfp Tagging Of Cd79a In Danio Rerio, Asia Eskaros
Crispr Cas9 Mediated Gfp Tagging Of Cd79a In Danio Rerio, Asia Eskaros
Liberty University Research Week
Danio rerio, commonly known as zebrafish, are well known to have an immune system that mirrors the human immune system. As such, Danio rerio is an excellent biological model for studying the immune system. This research team was attempting to study the activity of B-cells in the immune development of zebrafish. However, the team found that the exact location of B-cells in zebrafish throughout their development is not known. Thus, this research seeks to design a protocol to identify the location of B-cells throughout Danio rerio immune development. The team will be fulfilling this aim by tagging CD79a, also known …
Influence Of Scp1 On Cryptococcus Neoformans Virulence, Carleigh Warsing
Influence Of Scp1 On Cryptococcus Neoformans Virulence, Carleigh Warsing
Liberty University Research Week
Cryptococcus neoformans is the highest ranked pathogen on the Fungal Priority Pathogen List (WHO). Cryptococcal disease begins as pneumonia, crosses the blood-brain barrier, and develops into meningoencephalitis with a 41-61% mortality rate. While most commonly contracted by immunocompromised individuals, infections in immunocompetent individuals do occur. Treatments often produce severe side effects and increased resistance is a developing concern. Our research aims to identify a gene that can be targeted for more effective antifungal therapies. The SCP1 gene is involved in pH regulation and virulence in C. neoformans. Our research hypothesiszes that the SCP1 gene is crucial for the adaptation of …
Characterization Of The Aspergillus Flavus Rdia Gene With A Rdi1∆ Mutant Of C. Neoformans, Nicholas Jones
Characterization Of The Aspergillus Flavus Rdia Gene With A Rdi1∆ Mutant Of C. Neoformans, Nicholas Jones
Liberty University Research Week
Several members in the Aspergillus genus produce aflatoxin, the most potent naturally occurring carcinogen known. Regulation of aflatoxin biosynthesis has been studied for several decades as this mycotoxin is currently regulated by the USDA. While all the biosynthetic steps have been characterized, much remains to be elucidated regarding the regulatory network controlling its production. Expression data show that A. flavus rdiA clusters with the aflatoxin pathway-specific transcriptional regulator aflR. Deletion of rdiA resulted in increased septation interval and branching as well as severely decreased AF production. The ∆rdiA mutant phenotype is similar to the rdi1∆ mutant of C. neoformans and …
The Role For Casein Kinases In Glucose Sensing And Signaling In Yeast, Le Gia Han Nguyen
The Role For Casein Kinases In Glucose Sensing And Signaling In Yeast, Le Gia Han Nguyen
Liberty University Research Week
The yeast plasma membrane proteins Rgt2 and Snf3 are glucose sensing receptors (GSRs) that generate an intracellular signal for the induction of gene expression in response to extracellular glucose. The membrane-associated casein kinases Yck1 and Yck2 (Ycks) are involved in this glucose signal transduction pathway by transmitting the glucose signal from the plasma membrane to the nucleus. Here, we provide evidence that cell surface levels of Rgt2 are significantly decreased in a yck1Dyck2ts mutant by unknown mechanisms. We show that Rgt2 is phosphorylated on the putative Yck consensus phosphorylation sites in its C-terminal domain (CTD) in a Yck-dependent manner and …
Examination Of Putative Transcriptional Regulators In Cryptococcus Neoformans, Felice Kho
Examination Of Putative Transcriptional Regulators In Cryptococcus Neoformans, Felice Kho
Liberty University Research Week
Histone acetyltransferases (HATs) are enzymes involved in the transcriptional activation of genes. p300, a known HAT enzyme, acetylates histone tails at lysine and arginine residues. When histones are acetylated, they are more prone to promote transcriptional activation. Therefore, investigation into different HATs can aid in understanding gene regulation. Within C. neoformans, a pathogenic strain of yeast, there are a couple of putative HAT enzymes that are the focus of our research, the main one being the SAS3 gene, which shows a significant upregulation in expression when C. neoformans is allowed to grow in the absence of glucose . However, although …
Structural Comparison Of Fluoro-Phenolic Compound Degradation With Peroxidase Enzymes, Ashton Ware
Structural Comparison Of Fluoro-Phenolic Compound Degradation With Peroxidase Enzymes, Ashton Ware
Liberty University Research Week
Increased production of fluorinated drugs and agrochemicals over the last few decades has resulted in many concerns over the disposition of fluorinated waste products in the environment. The functional attraction to these compounds arises due to the difficulty in breaking C-F bonds, enhancing stability, and therefore the utility, of these compounds for their desired use. It is this stability that has prompted the concern over the persistent nature of these compounds in the environment. Effective strategies for degrading fluorinated aromatic waste have been developed, however excessive cost of reagents and impractical logistics for use justify the search for novel and …
Innovation At A Crossroads: The Supreme Court's Influence On Pharmaceuticals, Trade Policies, And Public Health, Beau Reeves
Innovation At A Crossroads: The Supreme Court's Influence On Pharmaceuticals, Trade Policies, And Public Health, Beau Reeves
DePaul Journal of Art, Technology & Intellectual Property Law
No abstract provided.
Beautifying The Human Experience: The Road To Knocking Out The Knockoff Industry Through Adaptions To Copyright & Design Patent Protections For Clothing, Moira Mccabe
DePaul Journal of Art, Technology & Intellectual Property Law
No abstract provided.
Spiritually Artificial: Divine Intersection Exploration, Christopher Jaus
Spiritually Artificial: Divine Intersection Exploration, Christopher Jaus
Liberty University Research Week
This paper examines the broad topic of personhood within the context of Artificial Intelligence (AI), and how consciousness, namely the free will aspect, can frame our interactions, especially when considering a typical evangelical hermeneutic. AI which is simply a Bio-Inspired design from God’s glorious creation has a long and rich history spanning almost 70 years. AI as a term was first coined in 1956, although the mathematics of computing in general, then dubbed “Turing Machines” was two decades earlier. Despite going through “AI winters” or periods where AI fell out of popularity due to high expectations and overpromising of researchers, …
In The Shadows Of Conquest: The Modern Maya Syncretic Legacy, Kimberly Weaner
In The Shadows Of Conquest: The Modern Maya Syncretic Legacy, Kimberly Weaner
Liberty University Research Week
Modern-day Guatemala is a unique illustration of the cultural and historical impacts of Spanish Colonialism. The Spanish Empire did not encounter a powerful central civilization to rival the likes of the Incas in Peru or the Aztecs in Mexico. Instead, Guatemala housed the remnants of the Maya, a once powerful civilization past their height. These Maya remnants fought hard to preserve their culture, forcing the Spanish conquistadors to come up with new methods of enslavement and authority. When the Spanish arrived in 1524, the Maya had collapsed into several small, fortified kingdoms, the strongest of which were the K’iche and …
Healing On The Home Front: Convalescent Homes In England During Wwi, Elizabeth Rogerson
Healing On The Home Front: Convalescent Homes In England During Wwi, Elizabeth Rogerson
Liberty University Research Week
This paper explores the response to soldiers needing rehabilitation in World War One and how convalescent facilities impacted the everyday lives of injured men, nurses, and military medicine. During the Great War, there was an influx of the diversity of injuries due to the expanse of biological and machine warfare. Recognizing that field hospitals were insufficient, England’s War Office executed a plan to requisition public facilities and use volunteer forces not only to heal English men but soldiers from across the world. This paper establishes the context for the convalescing system in England and then its accommodation and improvisation for …
Improper Divulgence: How Distrust And Poor Reporting Influenced Civilians Views Of The Three Mile Island Incident, Dylan Cumbo
Improper Divulgence: How Distrust And Poor Reporting Influenced Civilians Views Of The Three Mile Island Incident, Dylan Cumbo
Liberty University Research Week
This paper looks at how the media impacted the civilian opinion of the United States’ population on the Three Mile Island Incident. I argue that the media outlets reporting on the nuclear incident negatively impacted the public’s perception of the incident, making the disaster appear far worse than what was actually happening. Occurring on March 28, 1979, the meltdown of reactor number two at Three Mile Island, Pennsylvania, was the worst nuclear incident in United States history. Prior to the meltdown, United States citizens already had exposure to the pros and cons of radiation. Influenced by their experiences with nuclear …
Annotation Of Hypothetical Genes In Lactococcus Lactis Ssp. Il403, Jennifer A. Tangires
Annotation Of Hypothetical Genes In Lactococcus Lactis Ssp. Il403, Jennifer A. Tangires
Student Scholar Showcase
The human gastrointestinal tract (GIT) harnesses various microbial organisms involved in almost all processes of physiological homeostasis, among these are lactic acid bacteria (LAB). These bacteria, almost all of which belong to the order Lactobacillales, are able to produce lactic acid, and play an important role in food preservation because they produce bacteriocins. Bacteriocins are antimicrobial proteins that are used to fight off related bacteria in their environment that are competing for the same resources. This study focuses on a specific LAB strain, Lactococcus lactis ssp. IL1403 where 21.9% of its predicted genes have not yet been assigned a function. …
Short & Long-Term Consequences Of Cannabis Intake & Differences Between Occasional & Chronic Frequent Cannabis Use, Marilyn Huestis
Short & Long-Term Consequences Of Cannabis Intake & Differences Between Occasional & Chronic Frequent Cannabis Use, Marilyn Huestis
Oxford ICSB
As the medicalization and legalization of the United States continues to increase it is important to understand the short- and long-term consequences of cannabis use. The endogenous cannabinoid neurotransmitter system is critical for the appropriate functioning of survival functions including hunger, body temperature control, memory and reproduction. When individuals use cannabis, they hijack the normal functioning of the system that attempts to maintain homeostasis. The most important short-term consequence of cannabis use is the morbidity and mortality of driving under the influence of cannabis. Also, legalization reduced the perception of risk of using cannabis that leads to higher adolescent and …
Blast Injuries In Disaster Medicine, Robbie K. Paul
Blast Injuries In Disaster Medicine, Robbie K. Paul
Student Scholar Showcase
Disaster medicine is a division of medical care focused on immediate action in the field. Blast injuries can cause extreme injuries on impact meaning disaster medicine needs to be quick, efficient, and effective as possible. Medical professionals are facing an increase in blast-related injuries (Wolf et al., 2009). The military, paramedics, and organizations like the Red Cross use this branch of medicine. Blast injuries come from explosions caused by IEDs, pipe bombs, and household items malfunctioning. There is always room for improvement in medical care. How can we better understand the mechanism of injuries from blast explosions and improve disaster …
Program And Schedule For Ku Inspires, April 17 2024., Undergraduate Research Office, Kutztown University
Program And Schedule For Ku Inspires, April 17 2024., Undergraduate Research Office, Kutztown University
KU Inspires! Undergraduate Research Day
Conference featuring Undergraduate and Graduate Research done at Kutztown University by Kutztown University students. Sponsored by the Office of Undergraduate Research.
Bryant University Research And Engagement Day Schedule, Bryant University
Bryant University Research And Engagement Day Schedule, Bryant University
Bryant REDay (Research and Engagement Day)
No abstract provided.
Analysis Of The Neurophysiological Responses Of Lumbricina: An Invertebrate Model For Stem Education, Ragan Adkins, Bryce Allen, Michael Fultz
Analysis Of The Neurophysiological Responses Of Lumbricina: An Invertebrate Model For Stem Education, Ragan Adkins, Bryce Allen, Michael Fultz
2024 Celebration of Student Scholarship - Poster Presentations
The Invertebrates, specifically lumbricina, can serve as a model system for science education when studying neuron viability and the impact of various drugs on conduction velocity within the nervous system. Earthworms prove to be ideal candidates due to their easily stimulated and measurable large axon bundles. Earthworms are also inexpensive, noncontroversial, and easily sedated, making them suitable for STEM learning. Each earthworm underwent a standardized anesthetization procedure with an ethanol and water mixture before being placed on a nerve bath. They were then stimulated by an electrode to gather a control action potential. By measuring the speed at which …
Comparison Of Efficacy Of Antibody-Drug Conjugates In Cancer Treatment, Rebecca Bailey, Smita Joshi
Comparison Of Efficacy Of Antibody-Drug Conjugates In Cancer Treatment, Rebecca Bailey, Smita Joshi
2024 Celebration of Student Scholarship - Poster Presentations
Objective: To analyze the existing literature and evaluate the potential of antibody-drug conjugates (AD Cs) for superior efficacy in cancer treatment compared to chemotherapy.
The Mystery Of Seresto Collars, Katheryne Argueta, Smita Joshi
The Mystery Of Seresto Collars, Katheryne Argueta, Smita Joshi
2024 Celebration of Student Scholarship - Poster Presentations
Elanco Animal Health's (EAH) Seresto collars are used to protect canines and felines from common lxodids (ticks) and Siphonaptera (fleas). They work by slowly releasing the active ingredients onto the pet's skin throughout eight months. Recently, the Environmental Protection Agency (EPA) has revealed there have been a total of 100,000 incidents, 2,700 deaths in canines and felines, and 894 cases of harm to humans due to the use of Seresto collars. However, the link between these incidents and Seresto collars remains unclear. This literature review investigates the potential harm of Seresto collars. It compares the effects of major active ingredients, …
Comparison Of Nicotine Quantification In E-Liquids Using Volume-Based Sample Preparation Versus Mass-Based Sample Preparation, Serenity Baughman, Alyssa Roark, Emmalou Schmittzehe-Skarbek
Comparison Of Nicotine Quantification In E-Liquids Using Volume-Based Sample Preparation Versus Mass-Based Sample Preparation, Serenity Baughman, Alyssa Roark, Emmalou Schmittzehe-Skarbek
2024 Celebration of Student Scholarship - Poster Presentations
Questions are surrounding the accuracy of the reported levels of nicotine contained in e-liquids. Many of the studies show significant inconsistencies in the amount of nicotine reported on e-liquid products and the amount detected in the e-liquids. The current methods rely on preparing e-liquids for analysis by performing dilutions based on volume, but due to the viscosity of the liquids this preparation technique is prone to method errors. This project aims to compare the nicotine content in samples prepared by volume to those prepared by mass. This was done by first measuring the densities of several e-liquids. Those densities were …
Preliminary Terrestrial Palynological Re-Investigation Of The Type Coon Creek Lagerstatte, Tennessee, Usa, Ethan R. Lung, Keira J. Patton, Michael A. Gibson, Jack Garrett, Joshua Ratliff, Alan Youngerman, Mark Puckett, Alyson Brink, Thomas Byl, Masayuki Utsunomiya, Krostina F. Gardner, Jean M. Self-Trail, Jennifer M.K. O'Keefe
Preliminary Terrestrial Palynological Re-Investigation Of The Type Coon Creek Lagerstatte, Tennessee, Usa, Ethan R. Lung, Keira J. Patton, Michael A. Gibson, Jack Garrett, Joshua Ratliff, Alan Youngerman, Mark Puckett, Alyson Brink, Thomas Byl, Masayuki Utsunomiya, Krostina F. Gardner, Jean M. Self-Trail, Jennifer M.K. O'Keefe
2024 Celebration of Student Scholarship - Poster Presentations
The type locality for the Campanian Coon Creek Formation, located in McNairy County, Tennessee, is a well-known lagerstatte, with exceptionally preserved marine invertebrate and vertebrate remains in shallow shelf sediments. At the time of deposit ion, the type locality was located in an embayment proximal t o t he eastern margin of the Appalachia province that experienced alternately cool- and warm-water conditions, likely due to currents from both the Western Interior Seaway and Tethys. While marine in their entirety, the sediments contain significant quantities of terrestrial palynomorphs, especially near the top of the section and thus provide a snapshot of …
Meteorology Misconceptions Held By Students In An Earth Science Course For K-5 Teachers, Ivy Litton, Wilson Gonzalez-Espada, Jen O'Keefe, Md. Golam Kibria
Meteorology Misconceptions Held By Students In An Earth Science Course For K-5 Teachers, Ivy Litton, Wilson Gonzalez-Espada, Jen O'Keefe, Md. Golam Kibria
2024 Celebration of Student Scholarship - Poster Presentations
Students hold misconceptions when they confidently believe certain information, but that information differs from the commonly accepted scientific consensus. 1 Misconceptions accumulate over time due to a combination of incorrect perceptions of everyday experiences, over-simplifications and over-generalizations found in textbooks and the media, and incorrect or incomplete diagrams and analogies.2-7 Clausen described misconceptions held by teachers, and how they affected student learning. 8 After observing several teachers teaching about weather and climate change, he concluded that personal beliefs and values impacted what parts of science they emphasized in the classroom, resulting in students learning the content differently and inconsistently. This …
Can Dogs Sniff Out Covid-19? A Review Of Canine Scent Detection, Savannah Reed, Smita Joshi
Can Dogs Sniff Out Covid-19? A Review Of Canine Scent Detection, Savannah Reed, Smita Joshi
2024 Celebration of Student Scholarship - Poster Presentations
The purpose of this research is to explore if scent-trained canines are an effective way to screen for SARS-CoV-2, specifically, in high traffic areas. This method is being explored due to the canine's remarkable olfactory capabilities to identify individuals infected with SARS-CoV-2. This project provides a comprehensive review of past and ongoing research on canine scent detection for COVID-19 screening. The review synthesizes data from existing studies to assess the viability and reliability of this approach. Two research studies that determined the canines detection susceptibility and accuracy will be examined. The general mechanism used for training the canines included the …
Triplett Creek Watershed: Comparison Between 2009 And 2023 Escherichia Coli And Coliform Bacteria Levels, Emily Morgan, Heavenly Mays, Geoffrey W. Gearner
Triplett Creek Watershed: Comparison Between 2009 And 2023 Escherichia Coli And Coliform Bacteria Levels, Emily Morgan, Heavenly Mays, Geoffrey W. Gearner
2024 Celebration of Student Scholarship - Poster Presentations
Since 2009-2010, the Triplett Creek Watershed has continually produced samples that are inadequate for their designated uses according to the Kentucky Division of Water. The purpose of this study was to assess and compare the density of various bacteria in 14 different sample sites, specifically Escherichia coli, using both 2009 and 2023 data. This study occurred over 5 months with 6 different sampling events that took place from August to October 2023. By using and following the proper protocol for the IDEXX Quanti-Tray 2000, we were able to identify the total coliform and total E. coli (CFU/100 ml - MPN) …
Miocene Fungi From The Amazonas Region Of Peru: Preliminary Paleoclimatic And Paleoecological Reconstructions, Liberty F. Smallwood, Olivia Vander Espt, Christopher A. Marsh, Maggie E. Alden, Juan Filipe Montenegro, Diana Ochoa, Matthew J. Pound, Jennifer M. K. O’Keefe
Miocene Fungi From The Amazonas Region Of Peru: Preliminary Paleoclimatic And Paleoecological Reconstructions, Liberty F. Smallwood, Olivia Vander Espt, Christopher A. Marsh, Maggie E. Alden, Juan Filipe Montenegro, Diana Ochoa, Matthew J. Pound, Jennifer M. K. O’Keefe
2024 Celebration of Student Scholarship - Poster Presentations
Miocene sediments in the western Amazonas region record a unique mega-wetland ecosystem known as the Pebas System. This system existed under wetter and warmer than present conditions, prior to the final Andean uplift. Though the palynological record in the region has been studied extensively, fungal diversity remains poorly explored. Fungal remains from the Brazilian Amazonas have been identified to form-taxa only, without providing ecological or paleoclimatic information. We examine fossil-rich sediments from northeastern Peru that were deposited ca. 16.5 Ma, and therefore document the Miocene Climate Optimum warming. Here, the Fungi in a Warmer World (FIAWW) team applies the nearest …
Geoscience Archivism - Saving Morehead State's Collections One Rock At A Time, Miles Terry, Zachary Strait, Shelby Turner, Hayden Elmore, Caitlyn Gregory, Oliver Laiben, Jen O’Keefe
Geoscience Archivism - Saving Morehead State's Collections One Rock At A Time, Miles Terry, Zachary Strait, Shelby Turner, Hayden Elmore, Caitlyn Gregory, Oliver Laiben, Jen O’Keefe
2024 Celebration of Student Scholarship - Poster Presentations
Geoscience Collections at Morehead State University have not properly been organized or sorted since the Lappin Hall renovations in the mid-1990's. The collections were initiated by John C. Philley in 1960, James Chaplin 1961 and the collections card catalog developed by Jules DuBar when he arrived in 1967. Maintenance of the catalog appears to have ceased in 1981 when DuBar left the university. Specimens collected between 1981 and 1992 often have card-stock labels, but do not appear in the collection catalog. In recent decades, many of our cataloged samples have been lost and/ or damaged because of improper storage. Most …
Vesicle-Associated Membrane Proteins/Vamp Isoforms Orchestrate Platelet Cargo Trafficking, Jessie Begley, Aleah Wagner, Cameron Gibson, Jack Mcfarland, Shayan Mohammadmoradi, Harry Chanzu, Sidney W. Whiteheart, Smita Joshi
Vesicle-Associated Membrane Proteins/Vamp Isoforms Orchestrate Platelet Cargo Trafficking, Jessie Begley, Aleah Wagner, Cameron Gibson, Jack Mcfarland, Shayan Mohammadmoradi, Harry Chanzu, Sidney W. Whiteheart, Smita Joshi
2024 Celebration of Student Scholarship - Poster Presentations
Platelets are crucial to maintaining the vascular microenvironment. Upon vascular injury, they release cargo contents from their granules. These molecules, either made by platelets themselves or endocytosed from the blood, influence various processes like inflammation, immunity, and wound healing. Platelet granule release is mediated by Soluble N-ethylmaleimide Sensitive Factor Attachment Protein Receptors (SNAREs). To drive secretion, vesicle (v)-SNARE on granules and target (t)-SNARE on the plasma membrane form a SNARE complex that mediates fusion. Platelets contain Vesicle-Associated Membrane Protein (VAMP)-2, -3, -4, -5, -7, and -8.
Exploring Synergistic Antithrombotic Effects Of Natural Bioactive Compounds, Aleah Wagner, Jessie Begley, Jack Mcfarland, Smita Joshi
Exploring Synergistic Antithrombotic Effects Of Natural Bioactive Compounds, Aleah Wagner, Jessie Begley, Jack Mcfarland, Smita Joshi
2024 Celebration of Student Scholarship - Poster Presentations
Occlusive thrombosis, a leading cause of global morbidity and mortality, claims the lives of 1 in 4 individuals. Developing novel antithrombotic treatments is crucial, as conventional antiplatelet drugs, despite their potency, have limitations like increased bleeding risk. Natural bioactive compounds offer a promising alternative due to their safety, efficacy, and affordability. This research project aims to identify and investigate the synergistic and antagonistic effects of bioactive compound combinations in modulating thrombosis therapy.