Digital Commons Network^™

Ligand Efficacy Modulates Conformational Dynamics Of The Μ-Opioid Receptor, Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen

2020-Current year OA Pubs

The µ-opioid receptor (µOR) is an important target for pain management

A Precision Functional Atlas Of Personalized Network Topography And Probabilities, Robert J M Hermosillo, Ally Dworetsky, Babatunde Adeyemo, Caterina Gratton, Steven Petersen, Nico U F Dosenbach, Et Al.

2020-Current year OA Pubs

Although the general location of functional neural networks is similar across individuals, there is vast person-to-person topographic variability. To capture this, we implemented precision brain mapping functional magnetic resonance imaging methods to establish an open-source, method-flexible set of precision functional network atlases-the Masonic Institute for the Developing Brain (MIDB) Precision Brain Atlas. This atlas is an evolving resource comprising 53,273 individual-specific network maps, from more than 9,900 individuals, across ages and cohorts, including the Adolescent Brain Cognitive Development study, the Developmental Human Connectome Project and others. We also generated probabilistic network maps across multiple ages and integration zones (using a …

The Effect Of Gentle Yoga On Average Daily Step Count, Francesca D'Agrosa

Graduate Theses and Dissertations

While walking is a widely accessible form of exercise that is highly effective at increasing overall wellness (Kadir et al., 2019; Zhao et al., 2015) and is a recommended form of physical activity for overweight and obese individuals, studies still indicate low step counts and levels of physical activity in people with obesity (Shultz et al., 2011). Sedentary overweight individuals may avoid walking for several reasons, including physiological and/or biomechanical factors that make walking more difficult. This study attempted to explore and address these avoidant behaviors by employing a single-case ABAB reversal design to implement bi-weekly gentle yoga sessions over …

Vegetation Management During Establishment Of Native Grasses And Forb Plantings On Roadsides And Prairie Restoration, Rachel Woody-Pumford

Graduate Theses and Dissertations

North American prairies have been shrinking due to agricultural production, overgrazing, development of cities and towns, and climate change. However, integrated roadside vegetation management (IRVM) creates the opportunity to reestablish prairies along roadsides through planting native grasses and forbs. Utilizing postememergence (POST) herbicides registered for use along rights-of-way has the potential to remove invasive species and create space for newly establishing native grass and forb species. The use of clopyralid, florpyrauxifen-benzyl, metsulfuron, and quinclorac were found to be safe for use in plantings containing big bluestem (Andropogon gerardii Vitman) and butterfly milkweed (Asclepias tuberosa L.). However, florpyrauxifen-benzyl injured and stunted …

A Mixed Methods Exploration Of Interoceptive Awareness In Adults Who Stutter, Hazel Malcolm

Graduate Theses and Dissertations

Stuttering is commonly described as a disorder of speech fluency characterized by primary speech behaviors that are judged by external observers to be typical of stuttering, including part-word repetitions, prolongations, and blocks (i.e., silent prolongations or postural fixations). Despite wide use in the field of speech-pathology, definitions focusing on these ‘primary’ behaviors have also been criticized as ‘surface’ or ‘perceptual’ definitions that favor the experience of a listener over that of the speaker. Recent qualitative evidence suggests that, when asked, adults who stutter (AWS) instead define stuttering as an internal feeling or awareness of being ‘stuck’ that is surrounded by …

Variations Exist In Hospital And Patient-Reported Outcomes Following Total Hip Arthroplasty According To Biological Sex, Catherine Call, Andrew Lachance, Thomas Zink, Henry Stoddard, Callahan Sturgeon, George Babikian, Adam Rana, Brian J. Mcgrory

Costas T. Lambrew Research Retreat 2024

Introduction

• The effect of biological sex on the outcomes of THA remains unclear.

• Average combined data may mask sex-related variation and obscure clinically relevant differences in outcomes.

Dean's Research Newsletter, May 2024, Neil W. Schluger

SOM Dean's Research Newsletter

No abstract provided.

Stimulate The Senses: How The Great Outdoors Affects Mental Health, Kayleigh Hite

University Honors College

Mental health disorders and illnesses are a majority concern in societies across the globe in our current age. This paper examines the impacts and the benefits of the outdoors in relation to mental health. Various aspects of the outdoors, such as connection, nature-based therapies, and specific elements, will be addressed to see what kind of an impact the outdoors can have. Studies on these aspects will be reviewed and compared to determine if it is hugely beneficial and worth trying before starting new medications with a long list of side effects for mental health disorders. The findings have shown that …

Service-Learning And Cross-Cultural Impact: Preparing Underrepresented Students For An International Service-Learning Trip, Kalene Dean

University Honors College

No abstract provided.

An Examination Of Benefits Between Massage Therapy And Mental Health, Alexis Fears

University Honors College

Mental health affects millions of people every year, which is why finding effective treatment methods are important. This paper goes into a deep dive into the practice of massage therapy and its promising intervention for treated mental health disorders. Studies on the physiology of psychiatric disorders on the mental and physical states of the body will be reviewed. Following the examination of the effect the disorders have on the body, an examination of the effects of massage therapy on the physical and mental aspects of a psychiatric disorder will be provided. The findings show that massage therapy works to reduce …

Pcos: Comparing Inositol Supplementation To Metformin Treatment, Caitlin Liechti-Hawkins

University Honors College

The purpose of this literature review is to compare the viability of inositol versus metformin for the treatment of polycystic ovarian syndrome (PCOS). The research outlines the criteria for diagnosis and the many symptoms associated with the condition. The aim is to discover if inositol should be recommended for PCOS symptoms as a replacement for metformin. It was found that safety and popularity of the two options were important factors for physicians and patients to consider before choosing a treatment. Within these scopes, adverse effects, costs, regulation, and belief of treatment were compared. Findings indicated that inositol supplementation may possibly …

Architects Of Influence: Pioneers Who Shaped Today's Architecture, Carlynn Olinger

University Honors College

Architecture is a world that many people take advantage of and don’t understand the complexity behind it. There are many people in history who made a path for the way the world functions today, some of these people are architects. There are five men specifically: Antoni Gaudi, Frank Lloyd Wright, Ludwig Meis Van Der Rohe, Le Corbusier, and Louis Kahn, who pioneered the way for technology, education, aesthetics, and functionality of architecture. By researching we can learn who they were, what they did, and how they did it. Each one of these architects had different struggles, goals, backgrounds, and ideas. …

Keratin-Based Film: Waste To Bioplastic, Emma Bond

University Honors College

The solution to plastic lies in alternative materials, like bioplastics. One such possibility is keratin-based films. They are made from sources that are already deemed to be waste and that all regions of the world are abundant in. Manufacturing values a one-size-fits-all solution and keratin being plentiful worldwide fulfills that set standard. The films’ properties, which are important to the basic needs of a package, vary with different additives and the type of keratin used. α-keratin and β-keratin have different strengths and are found in nature in different sources. The resource focused on was chicken feathers, which produce more β-keratin …

Introduction To Nuclear Magnetic Resonance Spectroscopy In A Geochemical Setting, Evan Mack

University Honors College

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool that is heavily employed in organic chemistry, but lacks use in geochemistry. The technique is most useful for characterization and structural analysis of analytes, but also sees use in kinetics analysis, speciation, and detection. This work aims to answer these questions regarding NMR spectroscopy’s use in geochemical settings: Which nuclei are studied? For what purposes is each nucleus studied? What affects the scope of the technique and has caused it to not be widely used? How often is NMR spectroscopy used? What trends are there in the technique’s use? The …

Exploring The Experiences Of African American Middle School Stem Teachers, Stephen J. Minter

All Dissertations

As society is continuously in a space of changing politics and social structure, the educational landscape continues to be plagued by several inconvenient truths for African American educators. One truth is the lack of representation of African American teachers in science, technology, engineering, and math (STEM) areas. In a 2016 USDE report titled The State of Racial Diversity in the Educator, the report indicated that in the 2011-2012 school year, White educators made up 82% of the teachers in the nation.

Teachers often bring their life experiences, cultures and ideologies into their classrooms and campuses painting them with their assumptions …

Turtle Island Indigenous Science Conference, 21 - 23 May 2024

Indigenous Science Network

The First Nations University of Canada, File Hills Qu’Appelle Tribal Council, and University of Regina partnered to host the 2024 Turtle Island Indigenous Science Conference, held on Treaty 4 territory, the homelands of the nêhiyawak, Anihšināpēk, Dakota, Lakota, Nakoda peoples, and the Michif/Métis nation. The overarching theme of the conference was evidence-based approaches to Indigenous Knowledge and Science. Conference sessions included authentic and inclusive approaches to discovery and teaching; engaging youth in STEM; Indigenous engagement with water, land, and the environment; and relationships, partnerships, and sharing knowledges in a good way.

College Of Natural Sciences Newsletter, Spring 2024, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Page 1 Dean's Message
Page 2 New Faculty and New Club on Campus
Page 3 2024 URSCAD Awards
Page 4 Day of Scholars 2024
Page 5 SDSU's First Representation at the Association for Anatomy's 2024
Annual Conference
Page 6-7 2024 Honor's College Convocation
Page 8 Other Student Activities
Page 9 Faculty Awards
Page 10-11 Other News
Page 12 2024 Drone Day and American Association of Geographers Convention - Hawaii
Page 13 55th Annual Geography Convention
Page 14 2024 Stethoscope Ceremony
Page 15 Open PRAIRIE Data

Anti-Lgbt Legislation In Florida: A Prime Example Of States Mentally Harming Lgbt Youth, Kyla Tinsley

Northern Illinois University Law Review

While there has been a growing societal acceptance of LGBT individuals throughout the decades, anti-LGBT bills and laws within the states are on the rise—in particular, bills against LGBT youth. The most famous anti-LGBT law currently in place is Florida’s “Parental Rights in Education” law. The prevalence and inconsistent application of such legislation raises constitutional questions surrounding the rights of LGBT youth, as well as the negative effects the legislation has had on LGBT youth’s mental health and their perception of the legal system they are supposed to trust in and rely on. This Article discusses the impact state anti-LGBT …

Sound Marks, Deborah R. Gerhardt, Jon J. Lee

Minnesota Law Review Vols. 106:2 onward (2021-present)

A lion roars just before a film rolls. A doughboy giggles. A giant green man laughs a hearty, “Ho, Ho, Ho.” These iconic sounds are all federally registered as trademarks. They identify specific brands and distinguish their products and services from the competition. Human brains treat sounds like these as categorization tools and cognitive shortcuts--ideal trademark symbols. But what about the sounds your favorite toys or electronic devices make? Or those made by a fictional character in the latest blockbuster? This Article tackles these issues and others. We push back against the widely-held belief that all unconventional trademarks--product designs, colors, …

States’ Obligation To Provide For Trans Youth: How Medicaid Requires (Most) States To Provide Access To Puberty Blockers, Grace Worcester

Minnesota Law Review Vols. 106:2 onward (2021-present)

Over the last few years, many states have endeavored to strip minor access to gender-affirming healthcare, and these efforts have seen considerable success. By the end of 2023, twenty-two states had enacted legislation that limits youth access to genderaffirming healthcare. In line with these efforts, many states have created policies that exclude Medicaid coverage for gender-affirming puberty blockers--medications that delay the physical changes to one's body that occur with sexual maturity. These efforts contravene guidance from the medical community, which pronounces the importance of access to gender-affirming puberty blockers for transgender and gender-diverse youth, and often considers them medically necessary …

Analysis Of Social Behavior Of The African Great Apes During Feeding And Non-Feeding Contexts, Jessica Hale

Master's Theses

The three African great apes, bonobos, chimpanzees and gorillas, despite similar habitats, differ considerably in their sociality and feeding ecology. There have been many studies that have investigated the feeding ecology and social behaviors of these species, but there is extremely limited literature available on how feeding ecology may have affected ape social evolution. Chimpanzees are frugivorous, which forces them into close proximity when foraging given the clumped nature of this resource. Bonobos and gorillas, however, are fallback food consumers, which allow them to spread out as they forage. This thesis project aims to test the hypothesis that differences in …

Clonal Growth And Trait Variation In The Colorado Front Range: The Influence Of Elevation And Ecosystem, Jordan Conley

Master's Theses

Amid global climate change, exploring adaptive strategies among alpine flora, particularly through clonal growth, becomes critical for biodiversity conservation. This study aims to explore the patterns of dominance and distributions among clonal species across environmental gradients in the Colorado Front Range, employing a trait-based comparative analysis to understand the adaptive strategies of alpine flora and their implications for conservation amid rapid climate change. We focused on two species, studying traits like lateral spread, bud count, and bulbil numbers. Advanced statistical methods such as Permutational Multivariate Analysis of Variance (PerMANOVA) and Multi-Response Permutation Procedures (MRPP) were used to evaluate community compositions …

The Experience Of An Autistic And Neurotypical Sibling Dyad In Improvisational Music Therapy, Gianna Derusso

Theses & Dissertations

The purpose of this study was to explore the sibling relationship within improvisational music therapy, specifically the relationship between an autistic sibling and a neurotypical sibling. The following research question was posed: How does the relationship between a neurotypical and autistic sibling dyad present in improvisational music therapy? Subquestions to the research questions included: How do a neurotypical and autistic sibling dyad interact with one another within an improvisational music therapy session?, and How do a neurotypical and autistic sibling dyad interact with the music therapist within an improvisational music therapy session? An autistic and neurotypical sibling dyad was recruited, …

Natural Language Processing Methods For Parks, Conservation, And Outdoor Recreation Research, Danielle Dagan

All Dissertations

Recent advances in technology have increased the ability to access and manipulate large textual datasets. Natural language processing (NLP), the category of machine learning related to analyzing text data, is often used to understand humans. As with any tool or technology, it is important to critically examine how NLP approaches can support scientific advancement. This dissertation critically evaluates the use of NLP and machine learning in the domain of parks, conservation, and outdoor recreation. The dissertation begins with a novel conceptual chapter, which includes a scoping review of big data methods in outdoor recreation and introduces methodological concepts, best practices, …

Identification Of Rnai-Related Genes And Transcriptome Assembly Of Loblolly Pine (Pinus Taeda, L.) Seedlings Exposed To Insect-Specific Dsrna, Zachary Bragg, Lynne K. Rieske

Entomology Faculty Publications

Considerable research has focused on gene silencing in tree-feeding insects, but how trees recognize and process double-stranded RNA (dsRNA) engineered to target plant pests is unknown. We performed transcriptomic assembly, preliminary differential expression analysis, and in silico annotation on loblolly pine (Pinus taeda, L.) seedlings exposed to southern pine beetle-specific dsRNA. This pilot study sought to elucidate the baseline response of seedlings challenged with insect-specific dsRNA. Treated and untreated seedlings were sequenced and following transcriptome assembly 20 RNAi-related proteins (RRPs) were annotated. Differential gene expression analysis conducted using DESeq2 followed by pathway enrichment revealed 7131 differentially expressed transcripts, of which …

Persistent Identifiers And The Next Generation Of Legal Scholarship, Aaron Retteen, Malikah Hall-Retteen

Faculty Scholarship

This article discusses the importance of the most common persistent identifiers in scholarly communications—the digital object identifier and the ORCID identifier—to legal scholarship. Persistent identifiers help preserve and disseminate academic content and data-driven services that leverage this information standard are now integrated into the publication process. Because legal publishers have not widely adopted persistent identifiers, the legal discipline cannot enjoy the benefits offered by this system. This article looks at barriers to implementing persistent identifiers among legal publishers and provides an anecdotal example of creating a sustainable workflow between the law library and student-run law journals.

The Effect Of Microbial Bile Acid Metabolism On Clostridium Perfringens Virulence, Tahrir Jatli Alenezi

Graduate Theses and Dissertations

Clostridium perfringens is a predominant intestinal pathogen affecting both humans and animals, including chickens resulting in significant economic losses. In chapter I, I have overviewed the dynamics of the intestinal immune system, the composition of the intestinal microbiome, and how the microbiome influences inflammation in the development of Clostridium infection. The intricate interplay between immunity, microbiota, and their metabolites is likely critical in the pathogenesis of C. perfringens and uncovering these interactions may unveil new avenues for prevention and treatment. The objective of this chapter is to provide updated insights into the role of host-microbe interactions and their potential therapeutic …

Intervention Measures Alleviating Bacterial Chondronecrosis With Osteomyelitis In Broilers: Experimental Lameness And Feed Additive Treatments, Andi Asnayanti

Graduate Theses and Dissertations

As the global population grows, the supply and demand for meat have dramatically increased. The poultry industry has managed to satisfy the high demand for chicken meat through fast-growing broilers. The poultry breeder industry has successfully provided modern broilers with high liveability, feed efficiency, and processing yields through genetic selection of the traits of interest such as growth rate, feed conversion rate, and breast quality. Nevertheless, the intensive selection of modern broiler chickens for fast growth and feed efficiency leads to unintended side effects, such as excessive fat, low reproductive performance, leg abnormalities, low immunity, cardiovascular diseases, and metabolic disorders. …

The Water That Will Be: A Qualitative Look Into The Effects Of Visual Imagery On Participation In Water Conservation Initiatives, Shane Martin White

Graduate Theses and Dissertations

This dissertation explored the role of visual imagery in water conservation initiatives, focusing on its impact on public understanding, emotional connection, and willingness to participate. Drawing from the Theory of Planned Behavior and Affective Disposition Theory, the study investigated how art interventions can enhance comprehension and engagement with water conservation easements. Utilizing qualitative methods, including interviews, focus groups and PhotoVoice, data was collected from stakeholders in the Illinois River Watershed region. The research examined current levels of understanding regarding conservation easements, evaluated the effectiveness of visual imagery interventions in enhancing public awareness, and identified the potential for collaborative approaches between …

Developing Anisotropic Soft Matter As Functional Materials To Interface With Biological Systems, Homa Ghaiedi

Graduate Theses and Dissertations

Liquid crystals (LCs) constitute a subset of soft matter possessing hybrid characteristics from both liquid and crystalline phases. In this state, the center of masses remains uncorrelated similar to an isotropic phase, while the long axis of molecules aligns in parallel, resulting in molecules exhibiting orientational and positional order, either individually or concurrently. The directional alignment inherent in LCs arises from the asymmetrical shape and structure of the constituent molecules, causing a spontaneous self-assembly into ordered phases. This cooperative molecular behavior manifests distinctive optical features when subjected to cross polarizers. The remarkable sensitivity of LCs to external stimuli, including temperature, …