Digital Commons Network^™

Mediterranean Diet Information On Tiktok And Implications For Digital Health Promotion Research: Social Media Content Analysis, Margaret Raber, Haley Allen, Sophia Huang, Maria Vazquez, Echo Warner, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

Background: The Mediterranean diet has been linked to reduced risk for several cardiometabolic diseases. The lack of a clear definition of the Mediterranean diet in the scientific literature and the documented proliferation of nutrition misinformation on the internet suggest the potential for confusion among consumers seeking web-based Mediterranean diet information.

Objective: We conducted a social media content analysis of information about the Mediterranean diet on the influential social media platform, TikTok, to examine public discourse about the diet and identify potential areas of misinformation. We then analyzed these findings in the context of health promotion to identify potential challenges and …

Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch

School of Medicine Faculty Publications

A 78-year-old man with dementia experienced waxing and waning of symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure), the patient was treated with a near-identical repressurization in a hyperbaric chamber using compressed air. With four 1-h treatments at 1.3 Atmospheres Absolute (ATA) and concurrent administration of low-dose oral glutathione amino acid precursors, he recovered speech and showed improvement in activities of daily living. Regional broadcast media had documented his novel recovery. Nosocomial COVID-19 and …

The Recreational Ice Fishing And Ancillary Retail Communities On A Northern Latitude Lake: Yet-To-Be-Served Extension Audiences?, Mark Malchoff, Nate Trachte, Kristine Stepenuck

Journal of Extension

Ice fishing communities appear to be poorly described in Sea Grant Extension programming and planning documents. An intercept survey (N=52) of L. Champlain anglers revealed a broad age range and decades of participation. Opinions about spatial and temporal declines in ice cover were unrelated to state residency or age. Anglers expressing agreement with perceived declines in ice cover reported reductions in avidity and choice of fishing locations, while indicating little impact on species preference or fishing methods. Programming ideas to support this audience include distribution of economic data, ice forecasting, contaminant advisories for subsistence anglers, invasive species, and biodiversity conservation …

General Education And Special Education Teachers' Attitudes And Comfort Levels In Having Appropriate Conversations With Special Needs Students: A Causal-Comparative Study, Jessica Leah Hensley

Doctoral Dissertations and Projects

The purpose of this quantitative, causal-comparative study is to determine if there is a difference in special education and general education teachers’ attitudes and comfort level in teaching sex education. Students with intellectual disabilities need a sex education curriculum that can be extended if needed to ensure that they understand and are able to apply their knowledge to personal situations if they arise. The study’s sample includes high school and middle school special education and general education teachers. The sample was taken from participants who volunteered to take the survey via a link posted on social media account. A Microsoft …

A Missed Opportunity: The Relationship Between Language, Cognition, And Poverty In Early Childhood Among Bilingual Children, Saskia Barboza

Doctoral Dissertations and Projects

Human development is a continuous process with critical periods, and early childhood is part of that process, with internal changes prompted by external factors. An essential part of human development is language acquisition and cognitive skills which are shaped by heredity, brain structure, personal differences, social interaction, and socioeconomic background. In recent decades the exposure to multiple languages at home has been growing, causing differences between the language status (bilingual or monolingual) and the executive functions of developing children. Some previous studies have pointed out cognitive differences in bilingual children, while others have not. The present study observed three variables …

Pastoral Prose And Civic Engagement: Crafting The Call To The Public Square, Christopher Ian Thoma

Doctoral Dissertations and Projects

This thesis explores the relationship between creative writing techniques employed by pastors and congregational engagement in the public square. The central thesis posits that if pastors incorporate creative writing methods in extended weekly communications with congregants, then the necessary factors for engagement in the public square will be fostered, leading to attitudinal shifts demonstrated by increased congregational interest or participation in civil affairs. Through an extensive literature review, the thesis fairly examines historical and contemporary views of church and state, the Two Kingdoms doctrine, concepts relative to public square participation, Christianity’s waning cultural influence, communication science, developmental theory, literature familiarity, …

The Influence Of Working Memory And Anxiety In Adolescents, Donna M. Ward

Doctoral Dissertations and Projects

Literature supports a reliable link between lower working memory (WM) performance and higher anxiety, and both anxiety and WM are reported as comorbid with neurodevelopmental disorders (NDDs). This study sought to understand to what extent WM deficits and anxiety exists in adolescent NDD and non-NDD groups. Participants (N = 11,400; ages 9-10) were obtained from the Adolescent Brain Cognitive Development (ABCD) study archived dataset, with the approval of the NIMH approval. Participants in the dataset were recruited from 21 sites across the U.S. A Mann-Whitney U test, comparing the NDD (N=2756) and non-NDD (N=8644) groups was statistically significant, noting a …

Butte Priority Soils Operable Unit (Bpsou) Draft Final Insufficiently Reclaimed Sites Field Sampling Plan (Fsp) Bres No. 181 – Mountain Con-3 Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Synthetic Assembly Of Antibacterial Agents And Metal Chelating Ligands, Zachary Joseph Liveris

Dissertations

The exploitation of chemical synthesis exemplifies the notion of bridging both innovation and curiosity for the strategic assembly of sophisticated molecular infrastructures. By exerting this continuously evolving and versatile tool, synthesis has been applied in the development and influence of a myriad of ligands, biological probes, and persists to direct pharmaceutical innovation and modern medicine alike. Since pathogenic multidrug-resistant (MDR) microbial strains remain to be a persistent threat to both clinical healthcare and society, the need to develop selective and efficacious antibacterial agents that can impede microbe pathogenicity and regulate cellular mortality is paramount. In contrast to pharmaceutical development, organic …

A Hermeneutical Phenomenological Analysis Of Cross-Race/Cross-Ethnic Academic Advising First-Generation Latina/O Students Attending A Predominantly White Institution, Aisha A. Alvarez

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to explore the experiences of first-generation Latina/o students with non-Latina/o academic advisors at a Predominantly White Institution, Pink Ivy University. It is important to identify policies and practices for academic advising that can strengthen the relationship between first-generation Latina/o students and non-Latina/o academic advisors. Miller’s relational-cultural theory (RCT) guided this study. RCT was used to shape the sub-research questions and was used to frame the data analysis. First-generation Latina/o students over 18 who have completed at least one full year at the selected PWI and have used the services of their non-Latina/o …

Exploring Chaplains’ Lived Experience Concerning Mental Health Stigma And Suicidal Thoughts In The Military Context, Eric T. Victorino

Doctoral Dissertations and Projects

The empirical inquiry at the heart of this qualitative phenomenological research revolves around the identification of mental health stigma and suicidal ideation within the military context. This study delves into the lived experiences of military chaplains as they interact with service members grappling with thoughts of suicide and dealing with the associated mental health stigma. By examining the viewpoints of United States Army chaplains, we aim to gain a deeper insight into the perceived mental health stigma and its consequences for service members who are contending with suicidal thoughts. Chaplains’ unique viewpoints will contribute to an enriched comprehension of mental …

Water Quality Impacts Of Recycling Nutrients Using Organic Fertilizers In Circular Agricultural Scenarios, W. Lisenbee, A. Saha, P. Mohammadpour, R. Cibin, Jason Philip Kaye, C. Grady, Indrajeet Chaubey

Biological and Agricultural Engineering Faculty Publications and Presentations

CONTEXT

OBJECTIVE

METHODS

Cornus Officinalis Extract Activates The Keap1/Nrf2 Pathway And Delays T1d Onset In The Nod Mouse, Justin D. Fletcher

USF Tampa Graduate Theses and Dissertations

Type 1 diabetes (T1D) is an autoimmune disorder that results in the destruction of the insulin producing pancreatic β cells. The only therapeutic option following T1D clinical onset is exogenous insulin supplementation. At present, there is no cure for T1D and attempted interventional therapy has been focused on modulating the immune system. Few attempts have been pursued at preserving β cell function and survival. Here we provide a novel approach using extract from the fruit of the Cornus officinalis (CO) tree to preserve β cell function through the prevention of β cell stress. CO has been used in traditional Chinese …

To Revise Or Not Revise? Isolated Margin Positivity In Localized Pancreatic Ductal Adenocarcinoma, Victoria S. Wu, Henry J. Stitzel, John B. Ammori, Jeffrey Hardacre, Lee M. Ocuin

Faculty Scholarship

Background: The study determined the proportion of patients with pancreatic adenocarcinoma (PDAC) who had margin-positive disease and no other adverse pathologic findings (APF) using institutional and administrative datasets. Methods: Patients with clinical stage I or II PDAC in the National Cancer Database (NCDB 2010–2020) and those who underwent pancreatectomy at the authors’ institution (2010–2021) were identified. Isolated margin positivity (IMP) was defined as a positive surgical margin with no APF (negative nodes, no lymphovascular/perineural invasion). Results: The study included 225 patients from the authors’ institution and 23,598 patients from the NCDB. The margin-positive rates were 21.8% and 20.3%, and the …

Keep Fingers On The Cpg Islands, Xing Zhang, Robert M Blumenthal, Xiaodong Cheng

Faculty, Staff and Student Publications

The post-genomic era has ushered in the extensive application of epigenetic editing tools, allowing for precise alterations of gene expression. The use of reprogrammable editors that carry transcriptional corepressors has significant potential for long-term epigenetic silencing for the treatment of human diseases. The ideal scenario involves precise targeting of a specific genomic location by a DNA-binding domain, ensuring there are no off-target effects and that the process yields no genetic remnants aside from specific epigenetic modifications (i.e., DNA methylation). A notable example is a recent study on the mouse

Microglial P2y6 Calcium Signaling Promotes Phagocytosis And Shapes Neuroimmune Responses In Epileptogenesis, Anthony D Umpierre, Bohan Li, Katayoun Ayasoufi, Whitney L Simon, Shunyi Zhao, Manling Xie, Grace Thyen, Benjamin Hur, Jiaying Zheng, Yue Liang, Dale B Bosco, Mark A Maynes, Zhaofa Wu, Xinzhu Yu, Jaeyun Sung, Aaron J Johnson, Yulong Li, Long-Jun Wu

Faculty, Staff and Student Publications

Microglial calcium signaling is rare in a baseline state but strongly engaged during early epilepsy development. The mechanism(s) governing microglial calcium signaling are not known. By developing an in vivo uridine diphosphate (UDP) fluorescent sensor, GRABUDP1.0, we discovered that UDP release is a conserved response to seizures and excitotoxicity across brain regions. UDP can signal through the microglial-enriched P2Y6 receptor to increase calcium activity during epileptogenesis. P2Y6 calcium activity is associated with lysosome biogenesis and enhanced production of NF-κB-related cytokines. In the hippocampus, knockout of the P2Y6 receptor prevents microglia from fully engulfing neurons. Attenuating microglial calcium signaling through calcium …

New Valproate Regulations, Informed Choice And Seizure Risk, Heather Angus-Leppan, Rachel Arkell, Lance Watkins, Dominic Heaney, Paul Cooper, Rohit Shankar

Peninsula Medical School

Valproate is the most effective medication for generalised epilepsies, and several specific epilepsy syndromes. For some people, it will be the only medication to establish seizure remission, and withdrawing it carries risks of seizure recurrence and Sudden Unexpected Death in Epilepsy (SUDEP). It is also of proven efficacy for bipolar disorder and migraine prevention.Guidelines based on observational and epidemiological studies stress that maternal valproate related teratogenicity and neurodevelopmental effects are significantly higher than for other antiseizure medications (ASMs). It should, therefore, only be used if other medications are ineffective and after balancing the teratogenicity risk. Regulatory restrictions have changed prescribing …

Effect Of Incarceration On Prisoners Diagnosed With Mental Health Conditions: Trauma, Treatment, And Transitioning, Ingria S. Haywood

Doctoral Dissertations and Projects

A mental illness is a medical disorder that affects a person’s behavior, thoughts, and emotions. It also has an impact on social and cognitive functions. Misuse of substances, biological factors, or abuse, whether as a victim or a bystander to repeated abuse, are all variables that contribute to mental illness. The prevalence of mental illness among incarcerated prisoners is alarming, and it is nondiscriminatory in that it affects both men and women. Several variables contribute to inmates’ susceptibility to mental health problems. Anxiety disorders, depression as a mood disorder, dementia, and schizophrenia are examples of these. A diagnosis of mental …

Experiences Of Community Hospital Nurses In Blended Learning In Singapore: A Transcendental Phenomenological Study, Anqi Su

Doctoral Dissertations and Projects

The COVID-19 pandemic has led to many changes in the landscape of nursing care and nursing teaching and learning. One such change is the transition from traditional face-to-face learning to blended learning. While blended learning has many benefits and offers excellent opportunities for learning beyond the conventional methodologies and within the safety parameters of the COVID-19 pandemic, there is varied effectiveness from the literature review, and much is still being determined about community nurses' experiences in Singapore. Therefore, a qualitative transcendental phenomenological study on blended learning experiences among nurses in a community hospital in Singapore during the COVID-19 pandemic was …

Evidence-Based Practices For Military-Connected Students With Disruptive Behaviors Receiving Response To Intervention/Section 504 Services: School Counselors' Attitudes And Theoretical Orientation, Eddie Benitez

Doctoral Dissertations and Projects

This cross-sectional quantitative study compares primary and secondary counselors’ attitudes and theoretical orientation for evidence-based practices for military-connected students with disruptive behaviors receiving Response to Intervention and Section 504 services in Texas. This study is paramount for military-connected students with disruptive behaviors in closing gaps in academic performance, social-emotional skills, social justice, and multiculturalism in education. Military-connected students with disruptive behaviors confront the risk of not receiving evidence-based interventions through school services due to school counselors’ practices and theoretical approach. The researcher used a quantitative cross-sectional method and three analyses: Pearson r correlation, Multivariate analysis of variance (MANOVA), ANOVA, and …

A Single Cell Rna Sequence Atlas Of The Early Drosophila Larval Eye, Komal Kumar Bollepogu Raja, Kelvin Yeung, Yumei Li, Rui Chen, Graeme Mardon

Faculty, Staff and Students Publications

The Drosophila eye has been an important model to understand principles of differentiation, proliferation, apoptosis and tissue morphogenesis. However, a single cell RNA sequence resource that captures gene expression dynamics from the initiation of differentiation to the specification of different cell types in the larval eye disc is lacking. Here, we report transcriptomic data from 13,000 cells that cover six developmental stages of the larval eye. Our data show cell clusters that correspond to all major cell types present in the eye disc ranging from the initiation of the morphogenetic furrow to the differentiation of each photoreceptor cell type as …

Leveraging Integrated Rna Sequencing To Decipher Adrenomedullin's Protective Mechanisms In Experimental Bronchopulmonary Dysplasia, Subarna Palit, Amrit Kumar Shrestha, Shyam Thapa, Sandra L Grimm, Cristian Coarfa, Fabian Theis, Lukas M Simon, Binoy Shivanna

Faculty, Staff and Students Publications

Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly affecting premature infants, with limited therapeutic options and increased long-term consequences. Adrenomedullin (Adm), a proangiogenic peptide hormone, has been found to protect rodents against experimental BPD. This study aims to elucidate the molecular and cellular mechanisms through which Adm influences BPD pathogenesis using a lipopolysaccharide (LPS)-induced model of experimental BPD in mice. Bulk RNA sequencing of Adm-sufficient (wild-type or Adm+/+) and Adm-haplodeficient (Adm+/−) mice lungs, integrated with single-cell RNA sequencing data, revealed distinct gene expression patterns and cell type alterations associated with Adm deficiency …

Examining How Sexual Trauma Has Affected Women In Their Education: Creating A Community Of Awareness In The Educational System, Tyeasia Dorsey

Doctoral Dissertations and Projects

Sexual Trauma can have debilitating effects on women’s lives. The goal of this study was to focus on one aspect: how sexual trauma affects women’s academic performance, whether continuing education, a decrease in grades and grade point average (GPA), or the continuation of further educational studies. The underlying rationale for the study was the lack of research on the topic, especially in rural communities. This research utilized a qualitative study approach by conducting semi-structured interviews. This study was conducted to examine the mental health components of sexual trauma in women: a lack of support versus having a supportive environment and …

Trust And Its Implications For Trauma, Casidhe C. Daniels

Doctoral Dissertations and Projects

Trust presents as a complex and frequently misunderstood building block. While people often demonstrate an inherent belief that trust is naturally engrained in others, adverse life events and traumatic experiences can alter a person’s level of trust. Trust has the ability to change and become redefined. This can occur in a negative manner when trauma is incurred. While the individual’s is often innocent because of the challenges they have experiences, successes, failures, and traumatic events develop an ability to trust others and to what degree they face the lingering implications and diagnoses result.

Best Practices Associated With Medical Device Regulatory Strategy Success: A Case Study, Jonathan P. Ward

Doctoral Dissertations and Projects

In the evolving medical device industry, understanding how to achieve effective regulatory strategies is crucial. This study explored the foundations of regulatory strategy success in the United States, using qualitative insights from regulatory affairs professionals and industry investors. It identified operational, leadership, product design, and external factors essential for developing and implementing successful regulatory strategies. Key findings highlighted the importance of financial planning, agile regualtory process management, strategic knowledge integration, and proactive engagement with regulatory authorities. The study also pointed to the role of business ecosystems in supporting regulatory outcomes, suggesting a strategic planning approach that aligns product design with …

Leveraging Permutation Testing To Assess Confidence In Positive-Unlabeled Learning Applied To High-Dimensional Biological Datasets, Shiwei Xu, Margaret E. Ackerman

Dartmouth Scholarship

Compared to traditional supervised machine learning approaches employing fully labeled samples, positive-unlabeled (PU) learning techniques aim to classify “unlabeled” samples based on a smaller proportion of known positive examples. This more challenging modeling goal reflects many real-world scenarios in which negative examples are not available—posing direct challenges to defining prediction accuracy and robustness. While several studies have evaluated predictions learned from only definitive positive examples, few have investigated whether correct classification of a high proportion of known positives (KP) samples from among unlabeled samples can act as a surrogate to indicate model quality.

Promoting Organic Seed Systems: Directions For Extension Programming In Northeast Seed Systems, Megnot Mulugeta, Daniel Tobin, Carina V. Isbell

Journal of Extension

Despite the importance of seed availability to food and agriculture, seed systems have received scant attention within Extension research and practice. To address this gap, we designed a participatory needs assessment revolving around the 2021 Northeast Organic Seed Conference to assess individuals’ experiences within Northeastern organic seed systems and their opinions concerning their resource access, challenges, and sense of empowerment. Based on a post-conference survey, our findings suggest that Extension’s future efforts should focus on facilitating partnerships between and among community-based/non-profit seed groups, at-home gardeners, seed companies, university researchers, and legal scholars to promote equity and inclusion.

South Carolina Master Naturalist Program Evaluation: A Mixed Methods Approach, Susan T. Guynn, James H. Blake, Nathan Nemire, Joe Bible

Journal of Extension

The South Carolina Master Naturalist Program provides nature-based education to citizen volunteers who will promote environmental stewardship and is offered at six host sites across the state. We conducted a mixed-methods evaluation (the integration of qualitative and quantitative data) of the South Carolina Master Naturalist Program. Overall, the South Carolina Master Naturalist Program is achieving its mission but there were some differences between host sites. We identified where there were differences and why those differences may exist. We make recommendations to help strengthen the program across all host sites in the areas of program fidelity, delivery, and administration.

The Evolution Of Body Posture In The Sagittal Plane In The Sensitive Growth Period Of Children And Adolescents Undergoing Individual Scoliosis Therapy: A Pilot Study, Barbara Rosołek, Katarzyna Smółka, Diana Celebańska, Monika Szarajew, Anna Zwierzchowska

Baltic Journal of Health and Physical Activity

Introduction: The shape of the spine in the sagittal plane undergoes evolution, which occurs specifically in children and adolescents with idiopathic scoliosis (IS). The aim of the study was to verify the variability of body features and indicators in relation to the features and parameters of body posture in children and adolescents with IS. Materials and Methods: 61 measurements of children and adolescents (three age groups) with IS were collected. Body height, body weight, waist circumference, hip circumference, scoliosis major curve angle, thoracic kyphosis angle, lumbar lordosis angle, spine length, and pelvic tilt were measured. BMI and WHtR were calculated. …

Problems With Authority, Amy J. Griffin

St. John's Law Review

(Excerpt)

Judicial decision-making rests on a foundation of unwritten rules—those that govern the weight of authority. Such rules, including the cornerstone principle of stare decisis, are created informally through the internal social practices of the judiciary. Because weight-of-authority rules are largely informal and almost entirely unwritten, we lack a comprehensive account of their content. This raises serious questions—sounding in due process and access to justice—about whether judicial decision-making rests ultimately on judges’ arbitrary and unexamined preferences rather than transparent and deliberative processes. These norms of authority are largely invisible to many, including parties appearing before the courts. They govern the …