Digital Commons Network^™

Reconceiving Virtue: A Mengzian Adaptation Of Eudaimonic Virtue Ethics In Response To Contemporary Criticisms, Gina Elizabeth Lebkuecher

Dissertations

The primary question my dissertation aims to answer is: how might eudaimonic virtue ethics be reimagined to respond to contemporary criticisms from disability scholars, feminists, and empirical psychology? To answer this, I introduce the Eudaimonic View of Virtue, or EV, and propose a Mengzian adaptation of the EV (EV-M) in response to these criticisms. The EV captures the four core claims to which eudaimonic virtue ethical theories are committed: (i) virtues, in the sense of excellent character traits or dispositions, are the foundation of ethics or ethical action (i.e., aretaicism); (ii) virtue is at least partially constitutive of human well-being/flourishing …

The Impact Of Risk And Trust On Confrontations Of Sexism: The Role Of Goals, Emily H. Budde

Dissertations

Sexism is still persistent in the United States (Swim et al., 2001), especially in the workplace (Fitzgerald, 1993; Loy & Stewart, 1984), leading to many negative outcomes for women. Unfortunately, there is an assumption in America that targets of bias will confront the perpetrator in the moment. However, this is often not the case leading to a disconnect in society at the cost of the target (Gutek & O’Connor, 1995). Looking at targets’ decision-making process and the factors that influence it can provide more context for why targets respond the way they do. I tested whether behaviors following bias (i.e., …

Neurogenomics Of Competition And Parental Care In A Socially Polyandrous Shorebird, Tessa Mathur Patton

Master's Theses

Despite sharing largely similar genomes, females and males of the same species exhibit morphological, physiological, and behavioral differences. Sex-role reversal stems from a unique case of sexual selection in which females compete for mates and males conduct the majority of parental duties. We examined the extent to which aggression and parenting may be mediated by different neurogenomic mechanisms by comparing females versus males in the northern jacana (Jacana spinosa), a sex-role reversed shorebird. We hypothesized that sex differences in neural transcriptomic profiles explain sexual dimorphism in behavior. We conducted RNA-Seq in two brain regions within the social behavior network: the …

The Osteological Neutral Pose Of The Neck Of An Apatosaurine Sauropod Based On Virtual And Physical Models, Colin Don Boisvert

Theses and Dissertations

An array of sauropod taxa coexisted in Late Jurassic North America. How so many giant genera coexisted without competing for food is puzzling considering their potential metabolic requirements. One aspect of this question is neck posture, which has been much contested, both in terms of the intrinsic curvature of the neck and the resultant elevation of the head. Neck curvature is characterized by the Osteological Neutral Pose (ONP), wherein the intervertebral joints are in an undeflected state. This pose is crucial to understanding neck posture. The articulated series of presacral vertebrae 2-19 of an exceptionally well-preserved apatosaurine, BYU 18531, are …

Sensory Asic3 Channel Exacerbates Psoriatic Inflammation Via A Neurogenic Pathway In Female Mice, Chen Huang, Pei-Yi Sun, Yiming Jiang, Yuandong Liu, Zhichao Liu, Shao-Ling Han, Bao-Shan Wang, Yong-Xin Huang, An-Ran Ren, Jian-Fei Lu, Qin Jiang, Ying Li, Michael X Zhu, Zhirong Yao, Yang Tian, Xin Qi, Wei-Guang Li, Tian-Le Xu

Faculty, Staff and Student Publications

Psoriasis is an immune-mediated skin disease associated with neurogenic inflammation, but the underlying molecular mechanism remains unclear. We demonstrate here that acid-sensing ion channel 3 (ASIC3) exacerbates psoriatic inflammation through a sensory neurogenic pathway. Global or nociceptor-specific Asic3 knockout (KO) in female mice alleviates imiquimod-induced psoriatic acanthosis and type 17 inflammation to the same extent as nociceptor ablation. However, ASIC3 is dispensable for IL-23-induced psoriatic inflammation that bypasses the need for nociceptors. Mechanistically, ASIC3 activation induces the activity-dependent release of calcitonin gene-related peptide (CGRP) from sensory neurons to promote neurogenic inflammation. Botulinum neurotoxin A and CGRP antagonists prevent sensory neuron-mediated …

Cues And Identity: Assessing Substance Use Cues, Life Experience, And Context, Katelynn Carlsen

USF Tampa Graduate Theses and Dissertations

This project employs Ecological Momentary Assessment (EMA) methods alongside semi-structured interviews to examine substance use cues, or “triggers”, in the everyday context. This includes repeated assessment of participants’ behaviors and thoughts over time. EMA allows researchers to sample phenomena the moment they occur within the context. These methods are most used in psychology and clinical science. Current research on substance use relies on lab-based assessments to understand cues and their relationship to consumption (Carter and Tiffany 1999, Conklin and Tiffany 2003, Witteman et al. 2015). This analysis uses data collected by the Cues in the Everyday (CITED) Team. The CITED …

Cytokine-Supplemented Maturation Medium Enhances Cytoplasmic And Nuclear Maturation In Bovine Oocytes, Renata Blocher, Ying Liu, Tayler Patrick, Irina A. Polejaeva

Animal, Dairy, and Veterinary Science Faculty Publications

Bovine in vitro oocyte maturation (IVM) is an easy way to obtain oocytes for subsequent assisted reproductive techniques but is inefficient compared to in vivo maturation. Supplementation of three cytokines, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF1), or FLI, has increased oocyte maturation and embryo development in multiple species, but studies have not explored the oocyte differences caused by FLI IVM supplementation. This study aimed to assess important nuclear and cytoplasmic maturation events in high-quality oocytes. FLI-supplemented oocytes had a decreased GV (3.0% vs. 13.7%, p < 0.01) and increased telophase I incidence (34.6% vs. 17.6%, p < 0.05) after IVM, increased normal meiotic spindles (68.8% vs. 50.0%, p < 0.001), and an increased nuclear maturation rate (75.1% vs. 66.8%, p < 0.001). Moreover, in metaphase II oocytes, the percentage of FLI-treated oocytes with a diffuse mitochondrial distribution was higher (87.7% vs. 77.5%, p < 0.05) and with a cortical mitochondrial distribution was lower (11.6% vs. 17.4%, p < 0.05). Additionally, FLI-supplemented oocytes had more pattern I cortical granules (21.3% vs. 14.4%, p < 0.05). These data suggest that FLI supplementation in bovine in vitro maturation medium coordinates nuclear and cytoplasmic maturation to produce higher-quality oocytes.

Troponin: Think Before Testing, Shakirat Ganiyu, Fatimah Bello, Danielle Stone, Gregory Ruhnke, James Stone

School of Medicine Publications

This is a high-value care-based quality improvement project that was carried out to decrease inappropriate troponin testing in the emergency department (ED) of a tertiary health institution in the United States with the goal of promoting evidence-based practices, minimizing waste, and enhancing the quality of care.

Making Proteomics Accessible: Rokaixplorer For Interactive Analysis Of Phospho-Proteomic Data, Serhan Yılmaz, Filipa Blasco Tavares Pereira Lopes, Daniela Schlatzer, Marzieh Ayati, Mark R. Chance, Mehmet Koyutürk

Computer Science Faculty Publications

We present RokaiXplorer, an intuitive web tool designed to address the scarcity of user-friendly solutions for proteomics and phospho-proteomics data analysis and visualization. RokaiXplorer streamlines data processing, analysis, and visualization through an interactive online interface, making it accessible to researchers without specialized training in proteomics or data science. With its comprehensive suite of modules, RokaiXplorer facilitates phospho-proteomic analysis at the level of phosphosites, proteins, kinases, biological processes, and pathways. The tool offers functionalities such as data normalization, statistical testing, activity inference, pathway enrichment, subgroup analysis, automated report generation, and multiple visualizations, including volcano plots, bar plots, heat maps, and network …

Invertebrate Diversity From Deep Wells Of The Southern Boundary Of The Edwards Aquifer Of Southcentral Texas, Kathryn E. Perez, Valentin Cantu, Vanessa Saenz, J. Randy Gibson, Patricia Duncan, Benjamin T. Hutchins

School of Integrative Biological & Chemical Sciences Faculty Publications

This study examined the invertebrate fauna from three deep wells located at the Uvalde National Fish Hatchery in south-central Texas. These wells provide a water source from geological strata of the southern boundary of the Edwards Aquifer ranging in age from Lower Cretaceous to Recent. Forty-seven collections, sampled on a continuous basis from November 2020 to January 2022, produced a total of 738 specimens comprising 15 different species. These collections reveal a diverse crustacean assemblage along with dominant numbers of the stygobiotic snail Balconorbis uvaldensis. This study provides a preliminary survey for future investigations of unidentified crustacean species as …

Patrol Car Swab Sampling For Biological Agents, Haylie Corcho

USF Tampa Graduate Theses and Dissertations

Law enforcement personnel have a variety of responsibilities and subsequently, a variety of different exposures. Biological agents are common in the environment and therefore, these exposures are a concern in the profession. There is a gap in research into biological agent exposures in this profession, particularly how it relates to surface contamination and within the officers’ vehicles. There is also a lack of standardized decontamination procedures for patrol vehicles, allowing for the potential persistence of these agents. The purpose of this study is to understand which biological agents are most common in patrol cars, which areas within the vehicles have …

Changes In Plasma Concentrations Of Per- And Polyfluoroalkyl Substances After Bariatric Surgery In Adolescents From The Teen-Longitudinal Assessment Of Bariatric Surgery (Teen-Labs) Study, Brittney O Baumert, Sandrah P Eckel, Jesse A Goodrich, Zhenjiang Li, Nikos Stratakis, Douglas I Walker, Yinqi Zhao, Fabian Christoph Fischer, Scott Bartell, Damaskini Valvi, Xiangping Lin, Zoe Coates Fuentes, Thomas Inge, Justin Ryder, Todd Jenkins, Rohit Kohli, Stephanie Sisley, Stavra Xanthakos, Sarah Rock, Michele A La Merrill, Rob Mcconnell, David V Conti, Lida Chatzi

Faculty, Staff and Students Publications

Exposure to per- and poly-fluoroalkyl substances (PFAS) is ubiquitous due to their persistence in the environment and in humans. Extreme weight loss has been shown to influence concentrations of circulating persistent organic pollutants (POPs). Using data from the multi-center perspective Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohort, we investigated changes in plasma-PFAS in adolescents after bariatric surgery. Adolescents (Mean age = 17.1 years, SD = 1.5 years) undergoing bariatric surgery were enrolled in the Teen-LABS study. Plasma-PFAS were measured at the time of surgery and then 6-, 12-, and 36 months post-surgery. Linear mixed effect models were used to evaluate …

Uncovering The Dynamic Nature Of Fire Refugia Across Landscapes In Oregon's Western Cascades, Alec Scott Dyer

Dissertations and Theses

With increased fire activity, the presence of fire refugia is critical to support forest resiliency and mitigate large-scale vegetation conversion, however, the persistence of fire refugia within burn perimeters over time is uncertain. This study examines the dynamic nature of fire refugia by mapping the decline in forest cover over time, identifying spatiotemporal patch- and landscape-scale patterns and the biophysical drivers of delayed mortality following the 2020 Labor Day Fires occurring in Oregon’s western Cascades. After three years post-fire, delayed mortality accounted for an additional 8.5% of forest loss (total of 24,147 hectares in all five burns) compared to pre-fire …

An Analysis Of (Hu)Manid Using The Usf Donated Skeletal Collection: Estimating Sex And Ancestry For Edentulous Individuals, Natalie S. Wise

USF Tampa Graduate Theses and Dissertations

The Human Mandible Identification program, (hu)MANid©, enables anthropologists to estimate the sex and ancestry of unidentified skeletal remains from metric and morphoscopic variables from the mandible. The program is suitable for a variety of anthropological contexts, including forensic casework and bioarchaeological or paleoanthropological analyses. The purpose of this research project is to test the accuracy and applicability of the (hu)MANid program on edentulous mandibles. While the authors of (hu)MANid warn against data collection for edentulous mandibles, there are many circumstances in applied forensic casework where the unidentified person is edentulous. Edentulous individuals experience alveolar resorption, which is the loss of …

Around The Center, 1997 March/April, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on a new strategic plan.

Around The Center, 1996 November/December, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on quality management.

Evaluation Of An Autonomous Acoustic Surveying Technique For Grassland Bird Communities In Nebraska, Grace E. Schuster, Leroy J. Walston, Andrew R. Little

School of Natural Resources: Faculty Publications

Monitoring trends in wildlife communities is integral to making informed land management decisions and applying conservation strategies. Birds inhabit most niches in every environment and because of this they are widely accepted as an indicator species for environmental health. Traditionally, point counts are the common method to survey bird populations, however, passive acoustic monitoring approaches using autonomous recording units have been shown to be cost-effective alternatives to point count surveys. Advancements in automatic acoustic classification technologies, such as BirdNET, can aid in these efforts by quickly processing large volumes of acoustic recordings to identify bird species. While the utility of …

Editorial For "Parallel Cnn-Deep Learning Clinical-Imaging Signature For Assessing Pathologic Grade And Prognosis Of Soft Tissue Sarcoma Patients", Pegah Khosravi

Publications and Research

No abstract provided.

Effects Of Differing Radiation Methods On Charge Transport In Polymers, Zachary Gibson, Jr Dennison, Virginie Griseri

Presentations

The mitigation of deleterious arcing and sparking onboard spacecraft depends upon a thorough understanding of the electrical properties of the materials involved. This includes not only understanding steady-state parameters such as dark conductivity, but responses to the space environment as well. For example, radiation-induced conductivity drastically changes the conductivity of a material due to the presence of radiation. However, this change in conductivity diminishes away once the radiation is no longer present. There may also be permanent changes, or aging, in the material properties. The physical processes of aging can be complicated and are often difficult to model. Therefore, empirical …

Maturing Out Of Crime: A Test Of The Integrated Maturation Theory Of Desistance, Kelly E. Kortright

USF Tampa Graduate Theses and Dissertations

This dissertation partially tested a newer integrated theory, the Integrated Maturation Theory (IMT) of desistance. IMT argues that as maturation increases across five maturation domains (social role, civic, identity, psychosocial, and neurocognitive) the likelihood of offending decreases. Using a sample of serious justice-involved juveniles spanning ages 14-24 from the Pathways to Desistance Study, the individual and simultaneous maturation domain development of the social role, civic, identity, and psychosocial maturation domains, were explored for heterogeneity. Using a group-based trajectory modeling approach, including multi-trajectory modeling, this study advanced the understanding of maturation development by identifying sub-groups following declining trajectories of maturation and …

Seasonal Activity Patterns And Home Range Sizes Of Wolves In The Human-Dominated Landscape Of Northeast Türkiye, J. David Blount, Austin M. Green, Mark Chynoweth, Kyle D. Kittelberger, Dário Hipólito, Katarzyna Bojarska, Emrah Çoban, Josip Kusak, Çağan H. Şekercioğlu

Wildland Resources Faculty Publications

Gray wolves Canis lupus comprise one of the most widely distributed carnivore species on the planet, but they face myriad environmental and anthropogenic pressures. Previous research suggests that wolves adjust their time- and space-use seasonally to mitigate risks from humans, conspecifics, and other predators while maximizing their hunting and reproductive success. With many populations of wolves resettling in areas with dense human populations, understanding how wolves may adjust their temporal and spatial patterns in these more human-dominated landscapes is of high conservation importance. Typically, human presence causes wolves to increase their nocturnality and home range size. Here, we look at …

Microglial P2y6 Calcium Signaling Promotes Phagocytosis And Shapes Neuroimmune Responses In Epileptogenesis, Anthony D Umpierre, Bohan Li, Katayoun Ayasoufi, Whitney L Simon, Shunyi Zhao, Manling Xie, Grace Thyen, Benjamin Hur, Jiaying Zheng, Yue Liang, Dale B Bosco, Mark A Maynes, Zhaofa Wu, Xinzhu Yu, Jaeyun Sung, Aaron J Johnson, Yulong Li, Long-Jun Wu

The Brown Foundation: Institute of Molecular Medicine

Microglial calcium signaling is rare in a baseline state but strongly engaged during early epilepsy development. The mechanism(s) governing microglial calcium signaling are not known. By developing an in vivo UDP fluorescent sensor, GRABUDP1.0, we discovered that UDP release is a conserved response to seizures and excitotoxicity across brain regions. UDP can signal through the microglial-enriched P2Y6 receptor to increase calcium activity during epileptogenesis. P2Y6 calcium activity is associated with lysosome biogenesis and enhanced production of NF-κB-related cytokines. In the hippocampus, knockout of the P2Y6 receptor prevents microglia from fully engulfing neurons. Attenuating microglial calcium signaling through Calcium Extruder (“CalEx”) …

Neuroecological Links Of The Exposome And One Health, Agustin Ibanez, Lucia Melloni, Paweł Świeboda, William Hynes, Burcin Ikiz, Rym Ayadi, Massamba Thioye, Consuelo Walss-Bass, Bahar Güntekin, Jyoti Mishra, Mohamed Salama, Sarah Dunlop, Claudia Duran-Aniotz, Harris A Eyre

Faculty, Staff and Student Publications

This NeuroView assesses the interplay among exposome, One Health, and brain capital in health and disease. Physical and social exposomes affect brain health, and green brain skills are required for environmental health strategies. Ibanez et al. address current gaps and strategies needed in research, policy, and technology, offering a road map for stakeholders.

Challenges And Opportunities In Cancer Immunotherapy: A Society For Immunotherapy Of Cancer (Sitc) Strategic Vision, Leisha A Emens, Pedro J Romero, Ana Carrizosa Anderson, Tullia C Bruno, Christian M Capitini, Deborah Collyar, James L Gulley, Patrick Hwu, Avery D Posey, Ann W Silk, Jennifer A Wargo

Faculty, Staff and Student Publications

Cancer immunotherapy has flourished over the last 10-15 years, transforming the practice of oncology and providing long-term clinical benefit to some patients. During this time, three distinct classes of immune checkpoint inhibitors, chimeric antigen receptor-T cell therapies specific for two targets, and two distinct classes of bispecific T cell engagers, a vaccine, and an oncolytic virus have joined cytokines as a standard of cancer care. At the same time, scientific progress has delivered vast amounts of new knowledge. For example, advances in technologies such as single-cell sequencing and spatial transcriptomics have provided deep insights into the immunobiology of the tumor …

Indo-Caribbean Youth And Suicidal Behavior: A Systematic Review, Raul Ruiz Camacho, Shiryn D. Sukhram

Publications and Research

The suicide rates in Guyana, Suriname and Trinidad and Tobago are among the highest in the Americas, containing significant Indo-Caribbean populations that are suggested to be most vulnerable to suicide. This systematic review analyzes the existing literature and identifies knowledge gaps in risk and protective factors against suicide in these countries. The literature search conducted followed PRISMA guidelines using the PubMed and APA PsycInfo databases. The PRISMA flow diagram illustrated that eight scholarly papers were eligible for inclusion. Included literature examined stratified data focused on the aforementioned countries, as well as their Indo-Caribbean adolescent populations. Excluded literature did not mention …

Sea Urchins Like Zinc Oxide Nanometric Mitigating Meloidogyne Incognita Infection In Eggplant, Amir Khan, Manar Fawzi Bani Mfarrej, Mohd Farhan Khan, Shahbaz Khan, Peiter Malan, Saurabh C. Saxena, Mohd Muddassir, Faheem Ahmad

All Works

This study focused on the nematicidal potential of sea urchin-like zinc oxide nanometrics (SUZN) against the root-knot nematode Meloidogyne incognita. XRD, SEM, UV-vis spectroscopy, TEM, and EDX have been utilized to characterize the SUZN. Various SUZN concentrations (150–750 ppm) were examined for their implications for M. incognita second-stage juveniles (J2s) and egg masses, including mortality as well as hatching inhibition. The largest J2s hatching inhibition (83.07%) was seen at 750 ppm SUZN after 48 hours of incubation, whereas the lowest hatching occurred at 150 ppm when compared to the control. SUZN illustrated increased nematicidal efficiency with increasing concentration and incubation …

Microplastics In Estuaries, Maeve Gifford

UNH Today Archive

No abstract provided.

Mediterranean Diet Information On Tiktok And Implications For Digital Health Promotion Research: Social Media Content Analysis, Margaret Raber, Haley Allen, Sophia Huang, Maria Vazquez, Echo Warner, Debbe Thompson

Children’s Nutrition Research Center Staff Publications

Background: The Mediterranean diet has been linked to reduced risk for several cardiometabolic diseases. The lack of a clear definition of the Mediterranean diet in the scientific literature and the documented proliferation of nutrition misinformation on the internet suggest the potential for confusion among consumers seeking web-based Mediterranean diet information.

Objective: We conducted a social media content analysis of information about the Mediterranean diet on the influential social media platform, TikTok, to examine public discourse about the diet and identify potential areas of misinformation. We then analyzed these findings in the context of health promotion to identify potential challenges and …

Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch

School of Medicine Faculty Publications

A 78-year-old man with dementia experienced waxing and waning of symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure), the patient was treated with a near-identical repressurization in a hyperbaric chamber using compressed air. With four 1-h treatments at 1.3 Atmospheres Absolute (ATA) and concurrent administration of low-dose oral glutathione amino acid precursors, he recovered speech and showed improvement in activities of daily living. Regional broadcast media had documented his novel recovery. Nosocomial COVID-19 and …

The Recreational Ice Fishing And Ancillary Retail Communities On A Northern Latitude Lake: Yet-To-Be-Served Extension Audiences?, Mark Malchoff, Nate Trachte, Kristine Stepenuck

Journal of Extension

Ice fishing communities appear to be poorly described in Sea Grant Extension programming and planning documents. An intercept survey (N=52) of L. Champlain anglers revealed a broad age range and decades of participation. Opinions about spatial and temporal declines in ice cover were unrelated to state residency or age. Anglers expressing agreement with perceived declines in ice cover reported reductions in avidity and choice of fishing locations, while indicating little impact on species preference or fishing methods. Programming ideas to support this audience include distribution of economic data, ice forecasting, contaminant advisories for subsistence anglers, invasive species, and biodiversity conservation …