Digital Commons Network^™

Intellectual Property, Genetic Resources, And Associated Traditional Knowledge, N.S. Gopalakrishnan, Srividhya Ragavan, Narendran Thiruthy

Faculty Scholarship

The recently concluded WIPO Treaty on Intellectual Property, Genetic Resources and Associated Traditional Knowledge mandates disclosure requirements in patent applications, thereby creating an obligation to attribute the use of genetic resources and traditional knowledge. The WIPO member countries thus have an opportunity to modify their national patent laws, so that they can effectively control genetic resources and traditional knowledge. This article examines the choices that the biodiversity-rich countries have when designing their national legal systems to implement the treaty.

Rethinking The Pharmaceutical Knowledge- Economy: Patents, The Trips Agreement, And Skewed Utilitarianism In The Evolving Ideological Paradigms, Morris Odeh

Articles, Book Chapters, & Popular Press

The TRIPS Agreement introduced a unique globalized pharmaceutical patent economy. This article examines the social costs of this patent regime in low-income countries and makes three contributions. Firstly, it highlights how, in the early development of the patent system, nations perceived patents as privileges and displayed considerable reluctance in protecting pharmaceutical products and processes. This allowed net importers of technologies to replicate foreign innovations without the constraints of IP rights, and in some cases, invalidate unnecessary patents. However, this took a different turn towards the tail end of the 20th century when the patent norms and rules were harmonized and …

Effective Practices For Dual-Identified English Learners In Special Education Using A Quantitative Secondary Data Analysis Of Access For Ells Testing Results And Qualitative Case Studies, Brett Frayseth

School of Education and Leadership Student Capstone Theses and Dissertations

A student dual-identified to receive English learning and special education services is legally entitled to receive both services. Although there are recommendations for how to provide these services, there is little evidence of what has demonstrated success, despite there being schools which have been able to create such programs. This mixed methods research focused on identifying schools in Minnesota that successfully provided measurable growth in their dual-identified student population. Data were gathered from educators in those schools to understand how they found this success for their dual-identitfied students. This research began with a quantitative secondary data analysis of ACCESS for …

Vicarious Trauma Of Adult Tesol Educators: A Brief Investigation Of Screening Methods, Kenzie Howden

School of Education and Leadership Student Capstone Theses and Dissertations

This study explored the question: How do Adult Education and Literacy Program teachers in the Teaching English to Speakers of Other Languages context describe their experiences with teacher vicarious trauma, and does a commonly used screening tool show similar levels of teacher vicarious trauma?. Social science research has used the Professional Quality of Life (ProQOL; Stamm, 2010), a quantitative screening tool to explain vicarious trauma and related measures, and these methods have been recently adopted in research in adult education settings (Hickey et al., 2020). This study used a mixed methods approach, with 10 Adult Education and Literacy Program teachers …

Reflections On Influential Stem Experiences For Childhood Science Identity Development From East And Southeast Asian(Americans), Ellie Hechter

School of Education and Leadership Student Capstone Theses and Dissertations

Asian(Americans) are considered overrepresented in science, technology, engineering, and mathematics (STEM), but disaggregating demographic data shows that Southeast Asian(Americans) are underrepresented, underrecognized, and actively marginalized in the STEM workforce and degrees. The falsely monolithic view of Asian(Americans) has resulted in Southeast Asian(Americans) being unaccounted for in equity and inclusion initiatives. To better understand how to support Southeast Asian(Americans) in STEM, this study focused on childhood science identity development. A weak science identity is a significant barrier that can affect a student’s engagement and persistence in STEM and can be affected by numerous psychological, institutional, social, and cultural experiences. This study …

Neurological Foundations And Technological Interventions For Dyslexia: Advancements And Challenges, Piper Hutson, James Hutson

Faculty Scholarship

Dyslexia, a complex neurological condition affecting reading and language processing, is intricately tied to variations in brain structure and function. This article explores the neurological underpinnings of dyslexia, emphasizing phonological, visual, and attention-related impairments. Furthermore, the analysis highlights various types of dyslexia—phonological, surface, rapid automatized naming, and visual—while addressing their neurological correlations. It also investigates the relationship between dyslexia and other neurodivergent conditions, such as autism and ADHD, focusing on the neurological overlap and differences. To mitigate the challenges associated with dyslexia, advanced technologies such as virtual reality (VR) and eye-tracking are discussed for their diagnostic and intervention potential. These …

Understanding Bicuspid Aortic Valve: Global Prevalence, Genetic Factors, Long- Term Outcomes, Treatment Approaches And Knowledge Gaps, Grace Sligh

Honors Projects

Bicuspid aortic valve (BAV) disease is the most common congenital heart condition in the world, with a prevalence of 0.5 to 2.0 %, with the highest predominance in Caucasian men. This disease causes two leaflets to form instead of the typical three leaflet and can lead to many complications. This paper explores the global prevalence of BAV, highlighting observed variations between ethnicities and geographical background. It also examines the genetic factors contributing to the condition, including known hereditary patterns and emerging genetic insights. This review also addresses risk factors associated with BAV, such as environmental and developmental influences, as well …

Morphology And Molecular Systematics Support A New Species Of Pseudogonatodes (Squamata: Gekkota: Sphaerodactylidae) From Venezuela With A Remarkable Telescoped Skull, Walter E. Schargel, Christian Hernández-Morales, Juan D. Daza, Micheal J. Jowers, Andres Camilo Montes-Correa, Mayke De Freitas, Kathryn A. Sullivan, Tony Gamble, Aaron M. Bauer, Gilson A. Rivas

Biological Sciences Faculty Research and Publications

We describe a new species of miniaturized gecko (genus Pseudogonatodes) from the Peninsula de Paria in northeastern Venezuela. Externally, the new species resembles Pseudogonatodes furvus and Pseudogonatodes manessi, from the Sierra Nevada de Santa Marta in Colombia and the Central Coastal Range in Venezuela, respectively; however, it differs from these species in terms of molecular genetic data (12S rRNA, 16S rRNA, and c-mos), osteological characters, and scale counts. The new species is unique in skull osteology, and we adopt the term ‘telescoped’ from the literature to describe the overlap of bones in the snout, in particular the …

Investigating The Use Of Ai Tools In Education, Mercedes Byrd, James Martin Ii

Library Workshops

This workshop will introduce students, faculty, and staff to identify reputable AI resources of information (library site, libguides, databases), valid and relevant sources and efficiently appraise each.

Learning Objectives:

1. Begin to develop excellent evidence based practice by learning how to Identify reputable, valid, and relevant AI tools and academic resources (library site, libguides, databases) and sources (articles, websites, journals) of information and efficiently appraise each.

2. Discover AI tools and responsible uses of AI that can be utilized in your medical education.

Skill levels for attendees: Little to no experience

Software requirements: None

Aging Skeletal Muscle: Influence Of Obesity And Role Of The Exercise Responsive Nuclear Receptor Nor-1, Hector G. Paez

Alternative Theses and Dissertations (AETDs)

Skeletal muscle mass and function are critical components of overall health and quality of life. Advanced age is associated with skeletal muscle disease characterized by a loss of muscle mass, function, and quality. Indeed, low muscle mass and function is associated with poor disease outcomes and greater mortality, greater incidence of falls, and a high fiscal and societal cost. Aging contributes to a decline in skeletal muscle health through several intrinsic and extrinsic mechanisms including impaired nutrient sensing, mitochondrial dysfunction, inflammation, physical inactivity, and proteostatic imbalance. Obesity, an increasingly prominent public health concern, is becoming more common in the elderly …

Festival Of Research Abstracts, Fall 2024, College Of Science And Mathematics, Wright State University

Festival of Research

The collection of abstracts accepted for the Fall 2024 Festival of Research hosted by the Wright State University College of Science and Mathematics.

Methods Of Using Protein Palmitoylations Inhibitors, Robert Deschenes, Arunava Roy, Ahmed Ramadan, Subhra Mohapatra, Marcello Giulianotti

USF Patents

The present disclosure relates to methods of using palmitoylation inhibitors for reducing or treating enveloped virus infections.

The Effects Of Cannabinoids On Migration-Related Protein Expression In Ewing’S Sarcoma, Allison Lashall

Theses

Ewing’s sarcoma is an aggressive pediatric bone cancer that has low five-year survival rates, primarily due to metastatic disease and resistance of recurring tumors to traditional treatment options; therefore, novel treatment options are needed. The compound cannabidiol (CBD) has been shown to reduce cell viability, migration, and invasion in several tumor types, though the cellular mechanism of action is not well understood. Our lab has demonstrated the ability of CBD to reduce viability, migration, and invasion of Ewing’s sarcoma cells in vitro and is investigating differential protein and cytokine expression of known mediators of migration, such as intercellular adhesion molecule …

Emeriti News Fall 2024, Emeriti Council

Emeriti News

• Message from the Chair:
• Information about the Emeriti Council
• Wednesday II Events
• University News
• Faculty Senate Updates
• Student Scholarships
• In Memory

Modeling Threatened California Red Legged Frog (Rana Draytonii) Habitat With Maxent Using Environmental Dna Presence Via Quantitative Pcr, Charley Abernathy

AES Theses

As a sensitive and federally threatened species, the California Red Legged Frog (Rana draytonii) is known as a bioindicator because it most often occurs in complex healthy ecosystems capable of sustaining a diverse web of species. As humans affect natural habitats and climate change alters the environment, locating and monitoring sensitive species and their habitats is vital to supporting biodiversity and ecosystem health. Once ranging from Northern Mexico to the northern reaches of the California coast and Sierra Mountains, habitat of R. draytonii has been reduced to primarily the central coast of California. Environmental DNA ( eDNA) can be invaluable …

Examining The Effects Of Externally Mounted Biologgers On At-Sea Behavior And Reproductive Success In Adult Female Northern Elephant Seals, Mirounga Angustirostris, Using Computational Fluid Dynamics, Kali N. Prescott

Capstone Projects and Master's Theses

Over the past five decades, biologgers have been used to study animal behavior, physiology, and ecology. Externally mounted biologgers may have unforeseen effects on behavior, habitat use, foraging success, and reproductive success. Although guidelines exist for the recommended mass of biologgers on terrestrial animals, these guidelines are inappropriate for marine animals, which are more affected by buoyancy and drag. However, drag is difficult to measure directly necessitating the use of proxies based on physical characteristics of biologgers like frontal area. Northern elephant seals are a model species for studying the impacts of biologgers due to an existing long-term dataset collected …

Long-Term Tracking Captures The Timing Of Ontogenetic Niche Shifts In Northeast Pacific White Sharks, Ryan K. Logan, James M. Anderson, Echelle S. Burns, Yamilla Samara Chacon, Ryan Freedman, Emiliano García-Rodríguez, Elizabeth Jahn, Kady Lyons, Emily N. Meese, Zachariah S. Merson, John O'Sullivan, Patrick T. Rex, Emily Spurgeon, Brian S. Stirling, Connor F. White, Chuck Winkler, Salvador Jorgensen, Oscar Sosa-Nishizaki, Christopher G. Lowe

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Ontogenetic changes in area use, habitat use, and trophic interactions play an important role in the ecology, demography, and ultimately population dynamics of many species. Assumed to be driven by shifting life-history requirements, trophic niche shifts in white sharks (Carcharodon carcharias) are well documented, but the timing of the spatial niche shift that is hypothesized to occur with the trophic niche shift remains poorly understood. To document how fine-scale area use varies as sharks age and the timing of the ontogenetic spatial shift of this top predator, we tracked individual white sharks tagged as young-of-the-year or young juveniles …

Regulating Shipping Of Carbon Dioxide For Sequestration, Carolina Arlota, Michael B. Gerrard

Faculty Scholarship

A number of facilities intended for permanent sequestration of carbon dioxide are being developed in the United States. Several will be located on or near the coast of the Gulf of Mexico, making them easily accessible to ships. Meanwhile, in Europe there is substantial interest in capturing carbon dioxide from industrial operations, but currently inadequate sequestration facilities, and growing interest in shipping carbon dioxide for sequestration in the United States. This Article reviews the main U.S. federal laws applicable to transportation and geologic storage of carbon dioxide, including laws enacted to implement relevant international treaties. The Article also contextualizes its …

The International Legal Framework Of Oceanic Shipping Of Carbon Dioxide For Permanent Storage, Carolina Arlota, Michael B. Gerrard

Faculty Scholarship

The Intergovernmental Panel on Climate Change defines carbon dioxide capture and storage (CCS) as “a process in which a relatively pure stream of carbon dioxide (CO2) from industrial and energy-related sources is separated (captured), conditioned, compressed, and transported to a storage location for long-term isolation from the atmosphere.” Therefore, CCS encompasses a series of steps, at minimum: capturing carbon dioxide, its transportation to a storage site, and its injection into the subsurface for permanent storage. As such, CCS does not refer to any single activity or technology. This Article focuses on the transportation aspect of CCS and, more precisely, …

Low Prevalence Of Soil Transmitted Helminth Infection In Ugandan Children Hospitalized With Severe Malaria, Drew Capone, Nuzrath Jahan, Ruth Namazzi, Robert Opoka, Chandy John

Paediatrics and Child Health, East Africa

Co-infection by intestinal helminths and Plasmodium spp. may be common in endemic communities. Several studies have identified a relationship between helminth infection, Plasmodium spp. infection and malaria severity. However, the relationship is not well defined, and results are inconclusive. We analyzed stool samples from a cohort of children with severe malaria enrolled in two hospitals in Uganda from 2014-2017 and asymptomatic community children from the same household or neighborhood and enrolled at the same time, all 6 months to 48 months of age. We investigated if intestinal helminth infection modified risk of severe malaria. We extracted nucleic acids from stool …

Wooster Magazine: Annual Report Edition 2023-24, Caitlin Paynich Stanowick

Wooster Magazine: 2021-2030

The fall Annual Report Edition 2023-24 of Wooster magazine foreshadows the future of a Wooster education based on strengths in forward thinking, innovative academics, and collaborative inquiry. The annual financial review reports on the College’s operating revenues and expenses and highlights the ways donors have endorsed the Wooster education in the past year. Donors like Xiaorui “Ray” Bao ’11 and Dan Griffis ’94 share what compels them to give back to Wooster students and increase the value of their alma mater. Combined support from individual donors, reunion classes, and Wooster’s Women’s Advisory Board honor key figures from Wooster’s history including …

A Rose By Any Other Name: Mapping Taxonomic And Thematic Naming Errors Poststroke, Nicholas Riccardi, Deena Schwen Blackett, Abigail Broadhead, Dirk B. Den Ouden, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Rutvik H. Desai

Communication Sciences and Disorders Faculty Articles and Research

Understanding the neurobiology of semantic knowledge is a major goal of cognitive neuroscience. Taxonomic and thematic semantic knowledge are represented differently within the brain's conceptual networks, but the specific neural mechanisms remain unclear. Some neurobiological models propose that the anterior temporal lobe is an important hub for taxonomic knowledge, whereas the TPJ is especially involved in the representation of thematic knowledge. However, recent studies have provided divergent evidence. In this context, we investigated the neural correlates of taxonomic and thematic confrontation naming errors in 79 people with aphasia. We used three complementary lesion-symptom mapping (LSM) methods to investigate how structure …

Does The Use Of Dacc-Coated Dressings Improve Clinical Outcomes For Hard To Heal Wounds: A Systematic Review, Saskia Schwarzer, Jose Luis Lazaro-Martinez, Amanda L. Killeen, Paulo Alves, Andrea Gledhill, Erik Nygren, Lawrence A. Lavery, Matthew Malone

School of Podiatric Medicine Publications

Reports of overuse and antimicrobial resistance have fuelled some clinicians to adopt alternative wound dressings termed to be non-medicated or non-antimicrobials, which still claim antimicrobial or antibacterial activity. In this PROSPERO-registered systematic review, we evaluated the in vivo clinical evidence for the effectiveness of DACC-coated dressings in chronic, hard to heal wound-related outcomes. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) Framework was adopted as the template in constructing this systematic review. The PICO format (Population [or patients], Intervention, Comparison [control], Outcome/s) was used to identify key clinical questions in determining patient outcomes under two domains (infection control and …

Parallel Electrophysiological Abnormalities Due To Covid-19 Infection And To Alzheimer’S Disease And Related Dementia, Yang Jiang, Jennifer Neal, Pradoldej Sompol, Görsev Yener, Xianghong Arakaki, Christopher M. Norris, Francesca R. Farina, Agustin Ibanez, Susanna Lopez, Abdulhakim Al-Ezzi, Voyko Kavcic, Bahar Güntekin, Claudio Babiloni, Mihály Hajós

Neurology Faculty Publications

Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include EEG slowing (reduced alpha rhythm; increased slow waves) and epileptiform activity. An expert panel conducted a systematic review to present compelling evidence that cognitive deficits due to COVID-19 and to Alzheimer’s disease and related dementia (ADRD) are driven by overlapping pathologies and neurophysiological abnormalities. EEG abnormalities seen in COVID-19 patients resemble those observed in early stages of neurodegenerative diseases, particularly ADRD. It is proposed that similar EEG abnormalities in …

Surface Properties Of Enamel After Using Different Bleaching Agents, Hend Sayed Ahmed

Dentistry

No abstract provided.

Indirect Composite Color Stability And Surface Roughness After Finishing, Mohamed Fouad Haridy Prof. Dr., Sara Adel Botros Dr., Nermeen Hamada Hassan

Dentistry

This study aimed to evaluate the effect of different finishing and polishing systems (one-step, two-step, and multi-step) and the application of a diamond polishing paste on color stability, surface roughness, and surface morphology of a CAD/CAM composite block. A total of seventy-seven blocks from eight composite CAD/CAM blocks were used in this study. They were divided into three main groups (22 each) according to the different finishing and polishing systems used one-step, two-step, or multi-step systems. In addition to these groups, the control group (n = 11) has no treatment. Depending on whether the polishing paste was used, each group …

Effect Of Smoking And Finishing/Polishing On Roughness Of Nanohybrid-Composite, Sara Adel Botros, Mohamed Salama Dr., Fatma Makkeyah Ass. Dr., Mohamed Shamel Ass. Prof., Mahmoud Ankily Ass. Prof.

Dentistry

To evaluate effect of conventional cigarette and heated tobacco product smoking and finishing/polishing protocol on surface roughness of a nanohybrid composite. Thirty-six discs (6mm diameter/2mm thickness) fabricated from nanohybrid composite (Palfique LX5, Tokuyama, Japan) were assigned to 6 groups according to: tobacco product (conventional cigarette/LM, Philip Morris International Inc., Egypt; and heated tobacco/Heets, Russet, Philip Morris International Inc., Italy); and finishing/polishing protocol (control /discs cured against Mylar strip; finishing discs/Diamond Master Kit, FGM, Brazil; two-step polishing system/DIACOMP PLUS TWIST, EVE, Germany). Prior to finishing/polishing protocols, all specimens were wet ground with medium grit finishing stone (komet, Germany) as baseline. Following …

Influence Of Smoking And Finishing/Polishing On Composite Color Stability, Mohamed Samy Salama Dr., Sara Adel Botros, Fatma Makkeyah Ass. Dr., Mahmoud Ankily Ass. Prof., Mohamed Shamel Ass. Prof.

Dentistry

To assess the influence of conventional cigarette and heated tobacco product smoking and finishing/polishing systems on color stability of a nanohybrid composite. Thirty-six discs (2mm thickness/6mm diameter) fabricated from nanohybrid composite (Palfique LX5, Tokuyama, Japan) were divided to 6 groups according to: tobacco product (conventional cigarette/LM, Philip Morris International Inc., Egypt; and heated tobacco/Heets, Russet, Philip Morris International Inc., Italy); and finishing/polishing system (control /discs cured against Mylar strip; finishing discs system/Diamond Master Kit, FGM, Brazil; two-step polishing system/DIACOMP PLUS TWIST, EVE, Germany). All specimens were wet ground with medium grit finishing stone (komet, Germany) as baseline before performing finishing …

Ursinus Magazine, Fall 2024, Robyn E. Hannigan, Ed Moorhouse, Gundolf Graml, Ellen Labrecque, Ben Seal, Connor Donohue, Bill Connolly

Ursinus Magazine, 1995–Present

Capital research • Atomic tech • Hall of Fame author • A winning recipe • Taking a stand • Building bridges of understanding • Cutting the ribbon on Lower Wismer • Bear bites • Doctor Broadway • Resilience in motion • Mind-blowing pollution hiding in plain sight • History unearthed • Bear Beginnings • An artist's legacy: Francoise Gilot and the Bermans • Beyond Patterson's bleachers • The Hall at 50 • Class notes • Marriages • In memoriam • Annual Report and Year in Review

Suffering As The Way To God, Marjorie Shahani

LMU Theses and Dissertations

As a spiritual director and Christian, I desire to accompany women on their journey to a deeper personal relationship with God holding in tension the suffering Servant on the cross and the hope in the resurrected Christ. I long to illuminate their understanding of self-sacrifice and denial. Participating in Jesus’ suffering on the cross must not lead to neglect of oneself, denial of one’s human dignity, or the tolerance of any form of abuse – physical, emotional or mental. I comprehend the redemptive power in suffering for the love of God, but I also know Christ invites us to rejoice …