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Erau Admissions, Eric Wilson Feb 2025

Erau Admissions, Eric Wilson

ERAU SMART@ER Educators Conference

Admissions provides insightful information about the process of accepting and admitting students to ERAU as well as opportunities for students to apply for scholarships and awards.


Erau Admissions, Eric Wilson Feb 2025

Erau Admissions, Eric Wilson

ERAU SMART@ER Educators Conference

Admissions provides insightful information about the process of accepting and admitting students to ERAU as well as opportunities for students to apply for scholarships and awards. Session repeated on Friday at 10:00.


2025 Sdsu Data Science Symposium Abstracts, South Dakota State University Feb 2025

2025 Sdsu Data Science Symposium Abstracts, South Dakota State University

SDSU Data Science Symposium

Abstracts for keynotes, invited sessions, and posters for the 2025 SDSU Data Symposium.


The Application And Innovation Of Casgevy On Sickle Cell Disease, Emily Tackett, Le Thien Truc Pham, Hannah Salamie, Arin Wade, Allison Provenzale, Alexander Defranco, Ashley Jacob, Brianna Lu, Joshua Honaker, Amy Stockert Feb 2025

The Application And Innovation Of Casgevy On Sickle Cell Disease, Emily Tackett, Le Thien Truc Pham, Hannah Salamie, Arin Wade, Allison Provenzale, Alexander Defranco, Ashley Jacob, Brianna Lu, Joshua Honaker, Amy Stockert

Pharmacy and Wellness Review

Casgevy, sickle cell anemia, SCA, sickle cell disease, SCD, CRISPR/Cas9, hydroxyurea, hemoglobin, Hb, l-glutamine, voxelotor, Crizanlizumab, Lyfgenia, stem cells, genetics, pharmacogenetics, pharmacogenomics


Epr Imaging Workshop: From Theory And Practice To Applications, Arthur H. Heiss, Ralph T. Weber, Sandra S. Eaton, Gareth R. Eaton Feb 2025

Epr Imaging Workshop: From Theory And Practice To Applications, Arthur H. Heiss, Ralph T. Weber, Sandra S. Eaton, Gareth R. Eaton

TeachEPR Submissions

Methods of imaging and insights from imaging are described. Practical aspects of sample type and dimensions are described.

Workshop presented at the 27th International EPR Symposium, sponsored by Bruker BioSpin EPR Division and the University of Denver, in Denver, Colorado on August 1, 2004.


The Beacon, February 7, 2025, Beacon Staff Feb 2025

The Beacon, February 7, 2025, Beacon Staff

The Beacon, 2024-2025

Unsung Hero: Dr. Doug Anderson; County coffee shop showdown; Flipturn's album highlights vocal range; "Mufasa" deemed a crime against the original; Senior spotlight: double major Elliana Zerr; Dr. Bates leads youth program launch in Kenya; Beacon staff highlights and changes; Local brews and fresh reviews; Practical benefits of studying abroad; Archives hero at NW; The greatest romance story; Living a monastic life; The big game: Predictions from NW staff; Softball off to a great start to 2025 season; Students enjoy winter intramurals at NW; DeepSeek: a new AI competitor; Orange City to host RAGBRAI;


Cis-Regulation And Evolution Of Genes Involved In Immunity, Changxu Fan Feb 2025

Cis-Regulation And Evolution Of Genes Involved In Immunity, Changxu Fan

Arts & Sciences Electronic Theses and Dissertations

The mammalian genome contains ~20,000 genes. Some of these genes are essential for the cellular processes of most, if not all, cells, and are therefore expressed across a variety of cell types. Other genes, however, are involved in specialized processes such as defense against pathogens. These immunity-related genes are often only expressed in immune cells that require them to function. My dissertation addresses how the expression of immunity-related genes is regulated, with the rationale that such knowledge will inform the development of therapies to turn on/off immune genes, as a way of activating/inhibiting the effector functions of immune cells, which …


Workshop On The Epr Of Aqueous Samples, Gareth R. Eaton Feb 2025

Workshop On The Epr Of Aqueous Samples, Gareth R. Eaton

TeachEPR Submissions

The problem with water and other materials that absorb microwave energy are described. Dielectric properties are described as a function of frequency.

Workshop presented at the 25th International EPR Symposium on July 28, 2002.


Design And Application Of Molecularly Imprinted Polymers For The Detection Of Bpa, Pfoa, And Caffeine, Finbarr Buckley Feb 2025

Design And Application Of Molecularly Imprinted Polymers For The Detection Of Bpa, Pfoa, And Caffeine, Finbarr Buckley

Theses

Molecular Imprinted Polymers (MIPs) are polymer based solid phase extraction (SPE)recognition systems. MIPs were formulated using Acrylic Acid (AA) and Ethylene glycoldimethacrylate (EGDMA) to selectively target the following compounds Bisphenol A (BPA),Perfluorooctanoic acid (PFOA) and caffeine. This study presents novel MIPs for each targetqualitatively analysed with Raman Spectroscopy with Surface Enhanced Raman Spectroscopy(SERS) substrates. SERS can greatly enhance Raman signals allowing for detection of lowconcentration solutions. BPA, a possible carcinogen and hormone disruptor, is a very commonreagent in manufacturing as is known to leech into environmental and consumer products.PFOA, a constituent of polyfluoroalkyl substances (PFAS), can cause kidney and thyroiddisease, …


Evaluating Maternal Drug Use Disparities, Risk Factors And Outcomes In Northeast Arkansas: A Pre, During, And Post-Covid-19 Pandemic Analysis., Enrique Gomez Pomar, Johnna Berryhill, Sudeepa Bhattacharyya Feb 2025

Evaluating Maternal Drug Use Disparities, Risk Factors And Outcomes In Northeast Arkansas: A Pre, During, And Post-Covid-19 Pandemic Analysis., Enrique Gomez Pomar, Johnna Berryhill, Sudeepa Bhattacharyya

Pediatrics Faculty Publications

INTRODUCTION: The use of addictive substances remains a major health problem in the U.S. An increase in drug overdose and mortality was observed during the COVID-19 pandemic, especially in underserved populations. This surge also impacted pregnant women especially with the use of marijuana (THC) and opioids.

METHODS: Retrospective study analyzing mother-infant dyads with reported Meconium Drug Screen (MDS) results, from January 2018 through April 2023 at a reference hospital serving an urban and rural area of Arkansas. Due to the absence of universal screening, the prevalence of drug use was variable during the study period. An adjusted monthly positive rate …


2025-02-07 Agenda Book, Morehead State University. Board Of Regents. Feb 2025

2025-02-07 Agenda Book, Morehead State University. Board Of Regents.

Morehead State Board of Regents Agenda Books and Meeting Minutes

Agenda booklet for the Board of Regents meeting of February 7, 2025, which includes the meeting minutes of the meeting held on November 15, 2024.


The Ai-Robotic Prescription: Legal Liability When An Autonomous Ai Robot Is Your Medical Provider, Erika Sophia Grossbard Feb 2025

The Ai-Robotic Prescription: Legal Liability When An Autonomous Ai Robot Is Your Medical Provider, Erika Sophia Grossbard

University of Miami Business Law Review

As AI-driven healthcare accelerates, lawmakers must race against time to establish vital regulations, striving to protect patient safety in an era of increasingly autonomous medical devices. The real challenges arise when an automated AI medical device harms a patient during medical care, and the law has yet to clarify how liability should be allocated among its stakeholders. Currently, semi-autonomous robots are diagnosing medical conditions and performing surgeries. Eventually, autonomous AI medical providers will enter the market, capable of making independent medical decisions and providing treatment. These autonomous robots will function more like medical practitioners rather than merely as assistive tools …


Alternative Antimicrobial Strategies For Neonatal Infections, Anna Desmond Feb 2025

Alternative Antimicrobial Strategies For Neonatal Infections, Anna Desmond

Theses

Neonatal infections, a significant contributor to infant morbidity and mortality worldwide, are predominantly caused by pathogenic bacteria. Globally, bacterial sepsis accounts for 11.3% of neonatal deaths with Group B Streptococcus (GBS) being the leading cause, along with Escherichia coli, and coagulase negative staphylococci (CoNS). Neonatal infections caused by antibiotic resistant bacteria is now a worldwide concern, further increasing mortality rates and associated healthcare costs. Therefore, there is an urgent need to develop alternative antimicrobial strategies to combat resistance and/or enhance the efficacy of existing antibiotics. The overall aim of this thesis was to investigate alternative antimicrobial strategies for treating and …


Electro-Oxidative Deoxyfluorination Of Arenes With Net3·3hf, En Chih Liu, Sabrina M. Reich, Mayank Tanwar, Matthew Neurock, Long Luo, Melanie S. Sanford Feb 2025

Electro-Oxidative Deoxyfluorination Of Arenes With Net3·3hf, En Chih Liu, Sabrina M. Reich, Mayank Tanwar, Matthew Neurock, Long Luo, Melanie S. Sanford

Chemistry Faculty Research & Creative Works

This report describes the design, development, and optimization of an electrochemical deoxyfluorination of arenes using a tetrafluoropyridine-derived leaving group. NEt3·3HF serves as the fluoride source, and the reactions are conducted using either constant potential or constant current electrolysis in an undivided electrochemical cell. Mechanistic studies support a net oxidative pathway, in which initial single-electron oxidation generates a radical cation intermediate that is trapped by fluoride. The resulting radical undergoes a second oxidation reaction, followed by the loss of the leaving group to yield the fluoroarene product.


The Ethical Governance Of Artificial Intelligence: Using The Ai Integrative Risk-Based (Airb) Model To Achieve Compliance Risk Management, Miriam Weismann Feb 2025

The Ethical Governance Of Artificial Intelligence: Using The Ai Integrative Risk-Based (Airb) Model To Achieve Compliance Risk Management, Miriam Weismann

University of Miami Business Law Review

While undeniably powerful, artificial intelligence algorithms also pose significant risks. The ethical, legal, social, and scientific implications of various AI models can be profound, as demonstrated by the subprime mortgage crisis. This crisis, worsened by the unregulated use of derivative algorithms, is a stark reminder of the pivotal role of individual accountability, ethical responsibility, and regulation in preventing future “catastrophic harm.”1 This Article ventures into the uncharted territory of AI ethical governance and aims to advance AI scholarship and address the unresolved issue of ethical compliance management in AI. Employing a risk-based assessment tool is critical for developing regulatory and …


Monroe Work's Contributions To Public Sociology, Leonard A. Steverson, Gabrielle S. Kelly, Emma R. Torres Feb 2025

Monroe Work's Contributions To Public Sociology, Leonard A. Steverson, Gabrielle S. Kelly, Emma R. Torres

The Journal of Public and Professional Sociology

Abstract

Monroe Work was a Chicago School trained sociologist, criminologist, and researcher who, despite not being well-known in the social sciences, produced a body of research that is exemplified in what is now known as public sociology. Work was associated with prominent sociologist and activist W.E.B. Du Bois while working in Savannah, Georgia, and later with Booker T. Washington, with whom he worked at the Tuskegee Institute, heading the records and research department. Work was a talented researcher who worked behind the scenes with both Du Bois and Washington to provide needed research in a time of intense racial conflict. …


Opioid Use Disorder In Region 9 Of Louisiana: Using Labeling Theory To Understand The Layperson's Perception, Sara Elizabeth Dupree-Wolf Feb 2025

Opioid Use Disorder In Region 9 Of Louisiana: Using Labeling Theory To Understand The Layperson's Perception, Sara Elizabeth Dupree-Wolf

Walden Dissertations and Doctoral Studies

The overall research problem in this research study was that there were no current data related to the layperson's perception of opioid use disorder using labeling theory in Region 9 of Louisiana. This study is essential because opioid use disorder affects people worldwide, and the number of people diagnosed with opioid use disorder rises annually. Annually, thousands of people overdose, with a plethora of these overdoses resulting in death, due to opiate use. These deaths are unnecessary because there are treatment options and resources available. However, stigma and fear keep people from accessing potentially lifesaving resources. The purpose was to …


Ecological Influences On Informal Property Rights: Experimental Evidence, Erik O. Kimbrough Feb 2025

Ecological Influences On Informal Property Rights: Experimental Evidence, Erik O. Kimbrough

Economics Faculty Articles and Research

This paper explores the possibility that informal property right systems evolve unique features as a function of the characteristics of the resources over which they are established. We develop an experimental environment that allows us to test this hypothesis by comparing the emergence of property in (virtual) land when resource yields are either high- or low-variance and renewable or non-renewable. Previous research suggests that high-variance resources may lead to relatively insecure claims to property. Intuition suggests that this may be amplified when those resources are renewable. The experiments confirm that informal property rights adapt to resource characteristics in a manner …


Impact Of Developmental State, P53 Status, And Interferon Signaling On Glioblastoma Cell Response To Radiation And Temozolomide Treatment, Artem D. Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais S. Sabedot, Katherine Gurdziel, Susan M. Irtenkauf, Laura A. Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen L. Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila M. Poisson, Houtan Noushmehr, Douglas Ruden, Ana C. De Carvalho Feb 2025

Impact Of Developmental State, P53 Status, And Interferon Signaling On Glioblastoma Cell Response To Radiation And Temozolomide Treatment, Artem D. Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais S. Sabedot, Katherine Gurdziel, Susan M. Irtenkauf, Laura A. Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen L. Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila M. Poisson, Houtan Noushmehr, Douglas Ruden, Ana C. De Carvalho

Neurosurgery Articles

Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). In this study, we employed an integrative multi-omics approach, including targeted proteomics, transcriptomics, genomics, and DNA methylation profiling, to investigate the response of a representative panel of GBM patient-derived cancer stem cells (CSCs) to astrocytic differentiation and RT and TMZ treatments. Differentiated CSC progenies retained the expression of key stemness genes and survival pathways, while activating the BMP-Smad signaling pathway and upregulating extracellular matrix components. This was associated with increased resistance to TMZ, …


A Statistical Framework For Multi-Trait Rare Variant Analysis In Large-Scale Whole-Genome Sequencing Studies, Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, John Blangero, Joanne E. Curran, Michael C. Mahaney, Ravi Duggirala, Juan M. Peralta, Harald Hh Goring Feb 2025

A Statistical Framework For Multi-Trait Rare Variant Analysis In Large-Scale Whole-Genome Sequencing Studies, Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, John Blangero, Joanne E. Curran, Michael C. Mahaney, Ravi Duggirala, Juan M. Peralta, Harald Hh Goring

School of Medicine Publications

Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in WGS rare variant association analysis can improve statistical power over single-trait analysis, and also detect pleiotropic genes and regions. Existing multi-trait methods have limited ability to perform rare variant analysis of large-scale WGS data. We propose MultiSTAAR, a statistical framework and computationally scalable analytical pipeline for functionally informed multi-trait rare variant analysis in large-scale WGS studies. MultiSTAAR accounts for relatedness, population structure and correlation among phenotypes by jointly analyzing multiple …


Implementation Of Resiliency Training In The Biomedical Science Graduate Program First Year Curriculum, Kathryn M. Frietze Feb 2025

Implementation Of Resiliency Training In The Biomedical Science Graduate Program First Year Curriculum, Kathryn M. Frietze

HSC Education Days

No abstract provided.


A Pilot Academic Support Mechanism For Biomedical Sciences Graduate Program Students, Julie G. In, Kathryn M. Frietze Feb 2025

A Pilot Academic Support Mechanism For Biomedical Sciences Graduate Program Students, Julie G. In, Kathryn M. Frietze

HSC Education Days

No abstract provided.


A Mechanistic Exploration Of How Neighborhood Crime Exposure Relates To Neonatal Brain Function, Early Externalizing Behaviors, And Callous-Unemotional Traits, Rebecca Brady Feb 2025

A Mechanistic Exploration Of How Neighborhood Crime Exposure Relates To Neonatal Brain Function, Early Externalizing Behaviors, And Callous-Unemotional Traits, Rebecca Brady

Arts & Sciences Graduate Student Theses and Dissertations

Pregnancy through early childhood is a period of tremendous neural and behavioral development. Neuronal birth and migration occur prenatally and result in the formation of neonatal functional and structural networks. These early brain networks are a building block for postnatal development wherein infants rapidly learn a variety of new skills, including socioemotional skills such as emotion regulation and moral understanding. During the acquisition of these skills, even typically developing toddlers can act aggressively or impulsively; however, toddlers with high levels of externalizing behaviors are more likely to develop clinical externalizing disorders later in childhood and adolescence. As such, it is …


Predictors Of Treatment Adherence Among Individuals With Bipolar Disorder And Comorbid Substance Use Disorders, Monique Dawn Romeo Feb 2025

Predictors Of Treatment Adherence Among Individuals With Bipolar Disorder And Comorbid Substance Use Disorders, Monique Dawn Romeo

Walden Dissertations and Doctoral Studies

Individuals with bipolar disorder (BD) require lifelong treatment to manage their symptoms, and many also struggle with comorbid substance use disorders (BD-SUD) that complicate treatment adherence. Despite these challenges, there has been limited research on what factors predict successful treatment adherence in this population. This study was thus conducted to identify key predictors of adherence among individuals with BD-SUD. Several factors were examined, including age, gender, type of substance used at admission, opioid medication-assisted therapy, length of stay in inpatient psychiatric care, type of discharge service, and participation in self-help groups before discharge. The study applied a donut model framework …


The Impacts Of Software Development Methodologies On New Model Success Rate In The U.S. Automotive Industry, Marquita Aleatrice Tucker Feb 2025

The Impacts Of Software Development Methodologies On New Model Success Rate In The U.S. Automotive Industry, Marquita Aleatrice Tucker

Walden Dissertations and Doctoral Studies

Since 2017, the U.S. automotive industry has experienced a decrease in new-model launch success rate. A single 12-month delay in a new vehicle launch may cost a manufacturer up to $200 million. One component of automotive product development is software development. The research problem was a lack of understanding of the challenges with software development methodologies from the perspective of software developers, preventing managers from implementing methodologies, policies, and processes to improve the rates of successful new model launches. The purpose and the research questions were focused on exploring the lived experiences of software developers in the U.S. automotive industry …


Understanding The Relationship Between Food And Connection To God, Angela M. Hall Feb 2025

Understanding The Relationship Between Food And Connection To God, Angela M. Hall

Doctoral Dissertations and Projects

A person’s relationship with God is a personal one, as is the choice of the food we eat. Today we see more and more people struggle with unhealthy relationships with food. And our relationship with food affects more than just our physical health. Food and diet can play a role in how we hear from God. The present qualitative study aimed to understand the relationship between food and connection to God. Specifically, this study aimed to explain lived experiences with food and if diet affected connection to God. A total of twelve Christian, adult men and women participated in 1:1 …


Child Sexual Abuse And Mental Health: The Role Of Intrusive Thoughts And Spiritual Warfare, Sheriese S. Sanchez Feb 2025

Child Sexual Abuse And Mental Health: The Role Of Intrusive Thoughts And Spiritual Warfare, Sheriese S. Sanchez

Doctoral Dissertations and Projects

A number of psychological issues are experienced by individuals who have experienced CSA, including depression, anxiety, and bipolar disorder, as well as intrusive thoughts contribute to the perpetuation of the mental health problem. Studies have shown that spiritual practices, such as prayer, meditation, reading the Bible, and reciting scripture affirmations, can improve mental health, improving one’s psychological well-being. Further, intrusive thoughts may be initiated by dark spiritual influences. Despite ongoing research, there is a lack of integration between disciplines of science and biblical truth concerning the impact of immaterial spiritual dimensions on psychological states. To understand intrusive thoughts, one must …


The Communication Theory Of Argumentativeness: A Study Analyzing Argumentativeness And Demographics, Monika Joanna Yates Feb 2025

The Communication Theory Of Argumentativeness: A Study Analyzing Argumentativeness And Demographics, Monika Joanna Yates

Doctoral Dissertations and Projects

Quantitative research regarding the communication theory of argumentativeness is presented. The communication theory of argumentativeness, with its established argumentativeness conceptualization, scale, and measure, is central. The argumentativeness conceptualization, scale, and measure are used to posit argumentativeness groupings, which are then analyzed along with demographics within argumentativeness groupings. The following research questions are posed and answered: What is the distribution of argumentativeness within the general population? Are there identifiable segments/groupings of argumentativeness within the general population? Are there certain demographic characteristics that accompany the argumentativeness groupings of low, middle, and high argumentativeness measures? The conclusion finds: there are identifiable argumentativeness groupings; …


Worldview And Moral Injury: An Exploratory Multiple Case Study On Behavioral Health Providers’ Descriptions Of Moral Injury, Mark C. Lane Jr Feb 2025

Worldview And Moral Injury: An Exploratory Multiple Case Study On Behavioral Health Providers’ Descriptions Of Moral Injury, Mark C. Lane Jr

Doctoral Dissertations and Projects

The concept of Moral Injury continues to gain research traction in the helping professional fields. Researchers continue to debate different components of Moral Injury. Defining, assessing, and treating Moral Injury captures much of the psychological literature. Despite this, standardized holistic conceptualization and treatment have yet to be realized. Worldview influences all aspects of every endeavor in human life. As such, this qualitative exploratory multiple case study from a Christian post-positivist position explored how Department of Defense or Veteran Affairs behavioral health providers’ worldview influences their descriptions of the construct of Moral Injury, its morbidity, and how behavioral health providers choose …


Ontological Overtones Of Participatory Soteriology In Romans 8:1-17, Derek E. Wilder Feb 2025

Ontological Overtones Of Participatory Soteriology In Romans 8:1-17, Derek E. Wilder

Doctoral Dissertations and Projects

The burgeoning scholarly interest in the concepts of deification and Paul’s “in Christ” participatory soteriology necessitates a deeper exploration of their interrelation with the indwelling of the Holy Spirit. Regardless of the increase in recent scholarship, the connection between participation in Christ and the indwelling of the Holy Spirit remains underexplored. This study examines the relationship between deification, Pauline participatory soteriology, and pneumatology through an exegetical analysis of Romans 8:1–17. This exegetical framework posits that the believer’s union with Christ initiates a profound ontological metamorphosis, actualized through the Holy Spirit’s immanent indwelling and transcendent relational dynamic. The pneumatological dimension of …