Digital Commons Network^™

Do Chaperones Promote Protein Splicing?, Christopher Powell, Christopher Lennon Dr

Scholars Week

Intervening proteins (inteins) are translated within host proteins and removed by protein splicing. Inteins are abundant in the microbial world and are often found within essential genes involved in DNA replications, recombination, and repair. Recent studies have made efforts to understand conditional proteins splicing, whereby intein removal and subsequent host protein activation is regulated by environmental factors. However, within the cellular context, factors influencing protein splicing are still largely unknown. In this work, we probe whether the chaperonin system GroEL/ES promotes protein splicing in vivo. Chaperonins, a family of chaperone proteins, help proteins fold under normal and stressed conditions. …

Comparing Thermal Imaging Of New York City From 1988 To 2025, Amelia R. Slaton

Scholars Week

My project compared the urban heat island effect on New York City from 1988 to 2025. After looking at the risks associated with the heat island effect on local life I compared Landsat 5 imaging from 1988 and 1989 to Landsat 9 imaging from 2025 to find any differences between the thermal output of New York City. I then used images from both inner and long island area of New York from both time periods. As well as, the reason for New York's large thermal output compared to other surrounding areas and what the city is doing to combat the …

Rewilding: Native Gardening For The Pacific Northwest And North Coast, Peter Haggard, Jane Monroe

Textbooks and Manuals Series

Think of this book as a tool that will guide you through the journey of transforming your yard or lawn into a resilient garden landscape filled with vibrant native plants and endemic wildlife. Dig into a new way of gardening—one that nurtures not just your plants, but the planet. This book is for gardeners who want to get their hands dirty while creating thriving habitats for native wildlife. Whether you’re replacing bird feeders with natural food sources, growing your own produce while boosting biodiversity, or transforming urban and suburban spaces into havens for indigenous species, this guide will inspire you …

Detection Of Co2 Locally Generated By Formate Dehydrogenase Using Carbonate Ion-Selective Micropipette Electrodes, Seol Baek, Salvador Gutierrez-Portocarrero, Rokas Gerulskis, Shelley D. Minteer, Sean R. German, Henry S. White

Chemistry Faculty Research & Creative Works

Many technologies involve immobilizing catalysts such as enzymes on surfaces, and the catalytic activities or functional efficiencies of these surface-bound catalysts can vary depending on orientations, localized binding sites, active sites, and intrinsic molecular nature. Accurate and rapid quantification of reaction products from surface-immobilized catalysts is crucial for understanding the selectivity, mechanisms, and reaction dynamics of catalytic systems and for revealing heterogeneous catalytic activities and reaction sites for applications such as biosensors and energy conversion/generation systems. Here, we demonstrate the feasibility of localized enzymatic activity measurements using microscale carbon dioxide (CO₂)-sensitive ion-selective electrode (ISE) pipettes (0.5-2.5 μm tip …

Prenatal Exposure To Pm2.5 Concentration And Risk Of Preterm Birth In New Mexico; A Seasonal Pattern And Spatio-Temporal Modeling., Onyedikachi J. Okeke

Mathematics & Statistics ETDs

This study investigates the association between prenatal PM2.5 exposure and preterm birth risk in New Mexico (2014–2021). Using descriptive statistics, time series models, and spatial analyses, findings show an average preterm birth rate of 14.87 per 1,000 live births, with moderate correlation (r = 0.727) between PM2.5 levels and very preterm births. While traditional models revealed no significant global effect, spatial methods such as Geographically Weighted Regression (GWR) and Multiscale GWR uncovered strong spatial heterogeneity. PM2.5 effects varied by county (coefficients: -0.00154 to 0.00150), with clustering evident in 2018–2019 (Moran’s I = 0.155–0.174). Results highlight the limitations of global models …

Eric Malone V. Toyota Motor Sales

2025 Decisions

USDC for the Western District of Pennsylvania

Successful Leadership Strategies For Reducing Staff Turnover In Clinical Research Organizations, Tamala Burden

Walden Dissertations and Doctoral Studies

High employee turnover in clinical research organizations (CROs) disrupts research continuity, increases operational costs, and threatens the timely execution of clinical trials. High employee turnover is a critical concern to CRO leaders, as excessive employee attrition can delay developing and delivering new patient therapies and threaten organizational performance. Grounded in social exchange theory, the purpose of this qualitative pragmatic inquiry was to identify and explore employee-focused strategies that CRO leaders use to reduce employee turnover successfully. Data collection included semistructured interviews with six purposively selected CRO leaders, supplemented by publicly available records to triangulate findings. Following Braun and Clarke’s 6-step …

April 8, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Global Leaders Must Be Systems Thinkers. This Is A Problem. What To Do About It., Larry M. Starr, Phd

School of Business Faculty Papers

Two cognitive approaches are described about how people including global organizational leaders understand, formulate and try to intervene and solve problems. The prevailing, conventional approach is based on analytic thinking, established 400 years ago. A second approach is systemic thinking which is less than 100 years old, and unlikely to be taught, learned or applied. Increasing evidence about the nature of problems experienced by global leaders is that the context in which problems are occurring is volatile, uncertain, complex, ambiguous and hyperconnected (VUCAH). While analytic thinking, methods and tools are appropriate and effective for problems in contexts that are stable, …

Examining Physiological Responses To Misophonic Triggers, Christian O'Reilly, Xuan Yang, Sewon Oh, Doug Wedell, Svetlana Shinkareva

Faculty Publications

We collected and analyzed an array of biosignals (face electromyogram, skin electrodermal activity, peripheral temperature, and electrocardiogram) in 60 participants with and without misophonia, a condition characterized by decreased tolerance to innocuous sounds. Our goal was to objectively characterize the physiological response to misophonia triggering sounds. We found that misophonic responses can be objectively identified in some cases through atypical physiological reactions to triggering stimuli, though not all participants exhibited this response. Our analyses suggest a large interindividual variability in response to misophonic triggers and highlights the need for methodological adjustments in future experiments to increase the detectability of misophonic …

A Reliable And Efficient Detection Pipeline For Rodent Ultrasonic Vocalizations, Sabah Shahnoor Anis, Devin Mark Kellis, Kris Ford Kaigler, Marlene A. Wilson, Christian O'Reilly

Faculty Publications

Analyzing ultrasonic vocalizations (USVs) is crucial for understanding rodents' affective states and social behaviors, but the manual analysis is time-consuming and prone to errors. Automated USV detection systems have been developed to address these challenges. Yet, these systems often rely on machine learning and fail to generalize effectively to new datasets. To tackle these shortcomings, we introduce ContourUSV, an efficient automated system for detecting USVs from audio recordings. Our pipeline includes spectrogram generation, cleaning, pre-processing, contour detection, post-processing, and evaluation against manual annotations. To ensure robustness and reliability, we compared ContourUSV with three state-of-the-art systems using an existing open-access USV …

Deep Jansen-Rit Parameter Inference For Model-Driven Analysis Of Brain Activity, Deepa Tilwani, Christian O'Reilly

Faculty Publications

Accurately modeling effective connectivity (EC) is critical for understanding how the brain processes and integrates sensory information. Yet, it remains a formidable challenge due to complex neural dynamics and noisy measurements such as those obtained from the electroencephalogram (EEG). Model-driven EC infers local (within a brain region) and global (between brain regions) EC parameters by fitting a generative model of neural activity onto experimental data. This approach offers a promising route for various applications, including investigating neurodevel- opmental disorders. However, current approaches fail to scale to whole-brain analyses and are highly noise-sensitive. In this work, we employ three deep-learning architectures—a …

Disentangling Effects Of The Dr And Dq Isomers Encoded By The Hla Class Ii Haplotype Drb1*15:01/Dqb1*06:02 To Help Establish The True Risk Allele For Fviii Inhibitor Development In Hemophilia A, Vincent P. Diego, Bernadette W. Luu, Marcio A. Almeida, Jacob Galan, Eron G. Manusov, Juan M. Peralta, Satish Kumar, Joanne E. Curran, Harald H. H. Goring, Sarah Williams-Blangero, John Blangero, Tom Howard

School of Medicine Publications

Introduction: Hemophilia A (HA) patients (HAPs) with the human leukocyte antigen (HLA)-class-II (HLAII) haplotype DRB1*15:01/DQB1*06:02, and thus antigen presenting cells which express HLAII β-polypeptide chains that form heterodimers of DR15- and DQ6-serotypes, respectively, have an increased risk of developing factor (F)VIII inhibitors (FEIs)—neutralizing antibodies against the therapeutic-FVIII-proteins (tFVIIIs) infused to prevent/arrest bleeding. As DRB1*15:01 and DQB1*06:02 exist in strong linkage disequilibrium, association analysis cannot determine which is the actual risk allele.

Methods: To establish the true risk allele of this haplotype, we analyzed the tFVIII-derived peptides (tFVIII-dPs) bound to either the DR or DQ molecules that comprise the individual HLAII …

Living Nondirected Kidney Donation: A Psychoanalytic Case-Based Investigation Of Altruism And Its Implications For Psychosocial Evaluation Guidelines, Robert M. Guerin

Faculty Scholarship

Why donate a kidney to a stranger? The history of living nondirected kidney donation, so-called altruistic or Good Samaritan donation, is notable for its associated skepticism if not outright rejection. Since its possibility, transplantation institutes have been concerned over the motives of individuals who present to their clinics with the wish to donate a kidney to a stranger. Are these motives pure? Might there be ulterior motives or secondary gain? Or might these motives be pathological, derivative from a psychiatric disease or syndrome? Although attitudes toward the nondirected donor have improved, skepticism remains: Why, after all, benefit another in this …

Protpen: A Pipeline That Combines Sequence- And Structure-Based Approaches To Predict Protein Functions, Diya Mathai

Theses

Proteins of unknown function represent a significant gap in our understanding of biological processes, with many organisms, especially prokaryotes, harboring large portions of their proteomes that remain uncharacterized. For example, in Pseudomonas aeruginosa, a major human pathogen, a large proportion of proteins are categorized as unknown or hypothetical in function. The precise number varies across species, but studies have shown that up to 30–50% of proteins in bacterial proteomes can lack functional annotations. Addressing this gap is critical to understanding the biology and pathogenicity of such organisms. Recent advancements in computational tools, particularly those in sequence and structure-based prediction, offer …

Re-Framing The Master Narratives Of Learning Dis/Abilities Through An Emotion And Intersectional Lens, David I. Hernández-Saca

Faculty Publications

In this conceptual framework paper, I critically chronicle the historiography, policy, and scientific literatures of learning disabilities (ld) and provide a conceptual framework for reframing these as master narratives. I defined master narratives as the pre-existent sociocultural forms of interpretation. I interrogated the a) cultural-historical; b) the federal definition of ld within idea, c) the educational-professional academic and focused on, the d) social and emotional literature of ld. The master narratives from these literatures included: a) ld as a boy who struggles with reading, ld as a symbolic complex, and the legacy of the term "feebleminded", d) assumptions about learning, …

The Impacts Of Media Richness, Blurriness, And Beautification Of Online Dating Profile Visual Elements On Dating Outcomes, Minhao Dai, Shilin Xia

Faculty Articles

Introduction: Online dating is a popular way for individuals to connect today, and the visual elements of an online dating profile have become an essential part of online dating. The current study examined how media richness, visual blurriness, and beautification of an online dating profile’s visual elements would influence online dating outcomes.

Methods: We conducted an online dating experiment with 10 different conditions with younger adults between 18 and 35 (n = 389).

Results: The results showed that the richer visual elements and the beautified selfie in an online dating profile predicted a number of dating outcomes, including stronger …

The Fear Of Yahweh: Introducing Scripture’S Wisdom Literature For Biblical Counseling, Alexander Lee

Senior Honors Theses

Biblical wisdom literature is one of the most neglected areas of Scripture related to biblical counseling. Biblical counseling is formulated on the sufficiency of Scripture, so a deeper examination of any area of Scripture is sure to enlighten the biblical counselor. Wisdom in biblical counseling was introduced through an examination of the fear of Yahweh. A proper fear of Yahweh connects the counselee with the revelation of Jesus Christ in the New Testament, leading to a transformation of the client’s character toward a flourishing life. An existing case study was examined, highlighting how these findings can be implemented in the …

Topics In Knot, Quandle, And Quiver Theory, Brooke Jones

USF Tampa Graduate Theses and Dissertations

This dissertation explores the algebraic and combinatorial structures arising from the study of knot theory through the lens of quandles, their colorings, and associated quiver and ring constructions. It is organized around three central themes: the analysis of quandle coloring quivers for torus links, the development of polynomial invariants and quiver invariants for stuck knots and links, and the algebraic and graphical study of quandle rings. The first chapter begins with an introduction to relevant concepts throughout the dissertation.

In the second chapter, we classify quandle coloring quivers of torus links using dihedral quandles. We describe these quivers as weighted …

The Lynmouth Flood Disaster As A ‘Rural Enterprise Metabolic Rift’ And Securitising Rural Regions Against Future Hazards Of Planetary Collapse, Orlando Goodall

School of Law, Humanities and Social Sciences

This article advances a novel synthesis of two critical theoretical positions to reinterpret the Lynmouth flood disaster of 1952 – an event which caused the deaths of 34 people. Rural enterprise criminology and the metabolic rift concept are brought into dialogue to elaborate a foundation from which to articulate the multifactorial process that eventuated in the flood. The article fills an absence in the social sciences on the significant loss of life that moves beyond descriptive narratives of the tragedy and dated positivist epistemology. The article displaces determinist explanations of natural science and popular invocations of ‘acts of God’ and …

Ai Foundations And Applications: Summary Of A Panel Discussion At Loyola University Chicago, George K. Thiruvathukal, Dmitry Dligach, Shilpika, Michael B. Burns, Joseph Vukov, Fraser Turner, Mary Usher

Computer Science: Faculty Publications and Other Works

This document summarizes the panel discussion titled "AI Foundations and Applications," held at Loyola University Chicago as part of the "Forum on Global Affairs: Artificial Intelligence in a Globalized World" series. The panel brought together interdisciplinary experts to discuss the foundational aspects of artificial intelligence (AI), its applications, ethical considerations, and implications for education and society.

The Cardiovascular Care Of The Pediatric Athlete, Eli Friedman

All Publications

Sports cardiology broadly encompasses the cardiovascular care of individuals who place a high premium on habitual exercise, sports performance, and/or sports competition. Some of the essential aspects within sports cardiology include the preparticipation cardiac evaluation and the management of cardiac diseases in athletes. Although most sports cardiology practitioners are trained in adult cardiology, a significant number of individuals who participate in sports are pediatric-aged, < 18 years old. Up to two-thirds of children in middle and high school participate in organized sports or are involved in nonorganized recreational sports. The cardiovascular care of pediatric-aged athletes can be challenging because many of the classic tenets and principles in adult sports cardiology do not fully generalize to pediatrics, and there is a lack of the evidence base that may be present for adult athletes. The epidemiology, presentation, and progression of cardiovascular diseases can be significantly different between pediatric and adult athletes. The evaluation of potential diseases and management considerations may also differ between pediatric and adult athletes. Similar to adults, there are "gray zones" where it is difficult to differentiate between normal exercise-induced cardiac remodeling and true cardiac pathology, but the additional lack of normative standards further complicates assessments in pediatric athletes. Management decisions for pediatric athletes are generally based on limited data but carry substantial short- and long-term implications. Thus, shared decision-making as part of the determination of clinical management strategies and for sports participation is critical and requires the participation of the parents or guardian(s). In this state-of-the-art review, key differences between pediatric and adult-aged athletes are highlighted. Specifically, how to define the "pediatric athlete," consider cardiovascular adaptations observed among pediatric athletes, determine preparticipation screening options and optimal symptom-driven evaluations in children, and consider best practices for pediatric athletes with several key cardiac conditions are detailed. The purpose of this document is to represent the first primary reference available to providers who care for pediatric athletes with cardiovascular concerns.

Metabolite Analysis To Understand Factors Limiting Microbial Fermentation At High Substrate Concentrations, Bishal D. Sharma

Dartmouth College Ph.D Dissertations

Clostridium thermocellum, a thermophilic anaerobic bacterium, holds promise as a biocatalyst for conversion of lignocellulosic biomass into biofuels. This microbe has been subjected to various metabolic engineering strategies, including the deletion of genes encoding secondary fermentation products such as H₂, formate, acetate, and lactate, as well as the expression of heterologous genes to redirect carbon flux toward ethanol production. Despite these efforts, achieving economically viable ethanol titers remains a challenge. We hypothesized that studying how intracellular metabolite concentrations change as fermentation stops could reveal metabolic bottlenecks or regulatory mechanisms limiting ethanol production at high titers. However, metabolomics studies at …

Tumor-Derived Arachidonic Acid Reprograms Neutrophils To Promote Immune Suppression And Therapy Resistance In Triple-Negative Breast Cancer, Liqun Yu, Keziah Liebenberg, Yichao Shen, Fengshuo Liu, Zhan Xu, Xiaoxin Hao, Ling Wu, Weijie Zhang, Hilda L Chan, Bo Wei, Philip L Lorenzi, Yang Gao, Igor Bado, Luis Becerra-Dominguez, Charlotte Helena Rivas, Sergio Aguirre, Bradley C Pingel, Yi-Hsuan Wu, Yunfeng Ding, Jun Liu, David G Edwards, Livia S Eberlin, Xiang H-F Zhang

Faculty, Staff and Students Publications

The combination of immune checkpoint blockade and chemotherapies is the standard of care for triple-negative breast cancer (TNBC). However, initially, responsive tumors can still develop recurrences, suggesting acquired resistance mechanisms that remain poorly understood. Herein, we discover that TNBC cells surviving anti-programmed cell death protein-1 (anti-PD-1) and chemotherapy treatment accumulate neutral lipids. Disrupting lipid droplet formation in cancer cells reverses resistance and mitigates the immunosuppressive microenvironment. Single-cell RNA sequencing reveals a subset of neutrophils exhibiting a lipid-laden phenotype similar to adjacent tumor cells. Mechanistically, tumor-derived extracellular vesicles carrying lipids, including arachidonic acid (AA), mediate neutrophil reprogramming. Blocking dietary intake of …

The Cardiovascular Care Of The Pediatric Athlete, Peter N Dean, Julie A Brothers, Kristin Burns, Jonathan B Edelson, Susan Etheridge, Dermot M Phelan, Keri Shafer, Chris Snyder, Silvana Molossi, Alfred Danielian, Eli M Friedman, Jeff Hsu, Mustafa Husaini, Eugene H Chung, Matthew W Martinez, Aaron L Baggish, Benjamin D Levine, Jonathan H Kim, American College Of Cardiology Sports & Exercise Cardiology Council

Faculty, Staff and Students Publications

Sports cardiology broadly encompasses the cardiovascular care of individuals who place a high premium on habitual exercise, sports performance, and/or sports competition. Some of the essential aspects within sports cardiology include the preparticipation cardiac evaluation and the management of cardiac diseases in athletes. Although most sports cardiology practitioners are trained in adult cardiology, a significant number of individuals who participate in sports are pediatric-aged, < 18 years old. Up to two-thirds of children in middle and high school participate in organized sports or are involved in nonorganized recreational sports. The cardiovascular care of pediatric-aged athletes can be challenging because many of the classic tenets and principles in adult sports cardiology do not fully generalize to pediatrics, and there is a lack of the evidence base that may be present for adult athletes. The epidemiology, presentation, and progression of cardiovascular diseases can be significantly different between pediatric and adult athletes. The evaluation of potential diseases and management considerations may also differ between pediatric and adult athletes. Similar to adults, there are "gray zones" where it is difficult to differentiate between normal exercise-induced cardiac remodeling and true cardiac pathology, but the additional lack of normative standards further complicates assessments in pediatric athletes. Management decisions for pediatric athletes are generally based on limited data but carry substantial short- and long-term implications. Thus, shared decision-making as part of the determination of clinical management strategies and for sports participation is critical and requires the participation of the parents or guardian(s). In this state-of-the-art review, key differences between pediatric and adult-aged athletes are highlighted. Specifically, how to define the "pediatric athlete," consider cardiovascular adaptations observed among pediatric athletes, determine preparticipation screening options and optimal symptom-driven evaluations in children, and consider best practices for pediatric athletes with several key cardiac conditions are detailed. The purpose of this document is to represent the first primary reference available to providers who care for pediatric athletes with cardiovascular concerns.

Molecular Subtyping Of Hypertensive Disorders Of Pregnancy, Michal Elovitz, Elaine Gee, Nathaniel Delaney-Busch, Alison Moe, Mitsu Reddy, Arkady Khodursky, Johnny La, Ilma Abbas, Kay Mekaru, Hunter Collins, Farooq Siddiqui, Rory Nolan, Rupsa Boelig, Daniel Kiefer, Pamela Simmons, George Saade, Antonio Saad, Ebony Carter, Thomas Mcelrath, Stephen Quake, Mark Depristo, Carrie Haverty, Manfred Lee, Eugeni Namsaraev, Vincenzo Berghella, Ai-Ris Collier, Antonia Frolova, Esther Park-Hwang, Luis Pacheco, Elizabeth Sutton, Maneesh Jain, Kara Rood, William A Grobman, Joseph Biggio, Cynthia Gyamfi-Bannerman, Arun Jeyabalan, Morten Rasmussen

Department of Obstetrics and Gynecology Faculty Papers

Hypertensive disorders of pregnancy (HDP), including preeclampsia, affect 1 in 6 pregnancies, are major contributors to maternal morbidity and mortality, yet lack precision medicine strategies. Analyzing transcriptomic data from a prospectively-collected diverse cohort (n = 9102), this study reveals distinct RNA subtypes in maternal blood, reclassifying clinical HDP phenotypes like early/late-onset preeclampsia. The placental gene PAPPA2 strongly predicts the most severe forms of preeclampsia in individuals without pre-existing high risk factors, months before symptoms, and its overexpression correlates with earlier delivery in a dose-dependent manner. Further, molecular subtypes characterized by immune genes are upregulated in less severe forms of HDP. …

Assessment Of Heavy Metal Concentration In Blue Swimming Crabs From Dubai And Sharjah Fish Markets In Uae, Nehmat Elias Kharrat

Thesis/ Dissertation Defenses

Growing urbanization and industrialization along the UAE's coastline exposes human health and marine life at risk of increasing heavy metal pollution in marine ecosystems. This study evaluated the levels of 19 essential and non-essential elements in blue swimming crabs (Portunus pelagicus) collected from fish markets in Dubai and Sharjah. Among these, potentially harmful heavy metals included arsenic (As), copper (Cu), cadmium (Cd), nickel (Ni), lead (Pb) and mercury (Hg). The main goals of the study were (i) to evaluate whether the concentrations of these metals exceeded maximum permissible limits and (ii) to investigate if there were male and female specific …

Abstract Title: What Is Chaga? Unique Biochemistry Of The Sterile Conk., Anna Kreynes

Oxford ICSB

Fungal based supplements or functional mushrooms are growing in popularity worldwide. Among them, Chaga is attracting increasing attention for its broad immune-modulatory and anti-inflammatory properties. Chaga is unique among “mushroom” supplements as it is technically neither a mushroom (fruiting body), nor a sclerotia, as some researchers assert, but rather a sterile conk or canker that forms on trees, infected and colonized by mycelia of the pathogenic fungus Inonotus obliquus. Commonly associated with birch (Betula spp.), I. obliquus also parasitizes other hardwood species such as alder (Alnus), beech (Fagus), and ash (Fraxinus), found in boreal forests of northern Europe, Asia and …

Sample Storage Method And Collection Time Effects On Horse Hair Cortisol Concentrations, Grace Robertson

Scholars Week

Serum cortisol concentration is the gold standard for evaluating stress in horses. However, it can be affected by circadian rhythms, environmental factors, and other excitatory events. Hair cortisol is less subject to these variables and is less invasive to collect, but there is a lack of published information on hair cortisol concentrations in horses. The objectives of this study were to examine 1) the impact of sample storage (Room temperature vs. Frozen) and 2) the effect of collection date (spring vs. fall), on cortisol concentration in equine hair. It was hypothesized that Frozen samples would yield higher concentrations than Room …

Understanding Challenges To Breast Cancer Screening For African American Women In Detroit: A Study Of Social And Healthcare Inequities, Miranda Goodson, Whitney Bowyer, Erika Lopez, Anna Lundh

Medical Student Research Symposium

African American (AA) women have lower adherence to breast cancer screening guidelines, which may contribute to delayed diagnoses and reduced survival rates. These disparities are often influenced by limited access to quality healthcare and persistent inequities faced within Michigan. With Detroit's population being 77% AA, examining studies focused on the experiences of Black women within urban healthcare networks is essential to understanding the connections between demographic, socioeconomic factors, and breast cancer outcomes. To assess these studies, a literature search was conducted using Ovid Medline yielding 24 associated articles.

Mammogram rates among AA women in Detroit remain low, reflecting a complex …