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M-Polar Quadripartitioned Neutrosophic Graphs With Applications In Decision-Making For Mobile Network Selection, Basavaraj V Hiremath, Durga Nagarajan, Satham Hussain S, Hossein Rashmanlou, Farshid Mofidnakhaei May 2025

M-Polar Quadripartitioned Neutrosophic Graphs With Applications In Decision-Making For Mobile Network Selection, Basavaraj V Hiremath, Durga Nagarajan, Satham Hussain S, Hossein Rashmanlou, Farshid Mofidnakhaei

Neutrosophic Sets and Systems

No abstract provided.


A New Sdimsim Methods With Optimized Region Of Stability And Sustainable Development With Applications On Neutrosophic Data, A. Y. J. Almasoodi, Mohammed Kadhim Mohsin, Sarah A.Al-Ameedee, Mohammed Amer Shanyoor May 2025

A New Sdimsim Methods With Optimized Region Of Stability And Sustainable Development With Applications On Neutrosophic Data, A. Y. J. Almasoodi, Mohammed Kadhim Mohsin, Sarah A.Al-Ameedee, Mohammed Amer Shanyoor

Neutrosophic Sets and Systems

No abstract provided.


Neutrosophic Quasi-Xlindley Distribution With Applications Of Covid-19 Data, Rehab Alsultan, Amer Ibrahim Al-Omari May 2025

Neutrosophic Quasi-Xlindley Distribution With Applications Of Covid-19 Data, Rehab Alsultan, Amer Ibrahim Al-Omari

Neutrosophic Sets and Systems

No abstract provided.


Estimating And Testing Augmented Randomized Complete Block Designs: The Neutrosophic Approach, Abdulrahman Alaita, Hooshang Talebi, Yasser Al Zaim May 2025

Estimating And Testing Augmented Randomized Complete Block Designs: The Neutrosophic Approach, Abdulrahman Alaita, Hooshang Talebi, Yasser Al Zaim

Neutrosophic Sets and Systems

No abstract provided.


Statistical Characterization Of The Neutrosophic Moyal Distribution, Mansour F.Yassen, Adnan Amin May 2025

Statistical Characterization Of The Neutrosophic Moyal Distribution, Mansour F.Yassen, Adnan Amin

Neutrosophic Sets and Systems

No abstract provided.


Sea Turtles Sex & Survival, Bradley Walton, Nick Gorski May 2025

Sea Turtles Sex & Survival, Bradley Walton, Nick Gorski

Student Work

Sea turtles support the tourism industry in Playa Grande, Costa Rica. The expense of protecting the turtles against climate change is a challenge to saving the sea turtles.


Trophic Cascade, Nicole Callahan May 2025

Trophic Cascade, Nicole Callahan

Gandy Dancer Archives

No abstract provided.


Exploring The Relationship Between Suicidal Behavior And Obesity Among Young Hispanic Adults In The United States, Nadeen Salhadar May 2025

Exploring The Relationship Between Suicidal Behavior And Obesity Among Young Hispanic Adults In The United States, Nadeen Salhadar

Theses and Dissertations

The rates of obesity and suicidal behavior have continued to increase over the years among young adults in the United States. Previous research has indicated a relationship between obesity and suicidal behavior, primarily among women, yet minimal research has been done to examine factors that explain this relationship (i.e., mediators). This study investigated the role of depression, body dissatisfaction, body shame and guilt, insomnia, physical health, and social anxiety on obesity and suicidal ideation among 209 college-aged Latina women. The researcher hypothesized that there would be an indirect relationship between obesity and suicidal behavior through multiple variables. Mediation analyses via …


Emotional Outbursts In Latinx Autistic Youth With Intact Or Non-Intact Families; Frequency, Severity, And Socio-Demographic Correlates, Sandra Lucia Masso Hernandez May 2025

Emotional Outbursts In Latinx Autistic Youth With Intact Or Non-Intact Families; Frequency, Severity, And Socio-Demographic Correlates, Sandra Lucia Masso Hernandez

Theses and Dissertations

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction, communication, and restricted repetitive behaviors. One of the core difficulties in individuals with ASD is related to emotional outbursts. Emotional outbursts (EO) are behavioral episodes in response to situations, environmental and physiological stimuli that occur in an extreme, unpleasant, sometimes aggressive way, often disproportionate to the context. Considering the impacts that EO’s can cause in populations with neurodevelopmental disorders and on the well-being and mental health of parents/caregivers, the need arises to evaluate these populations. Due to the core characteristics of ASD (such as a rigid mentality, …


Bile Acid And Microbiome Interactions In The Developing Child, Mary Elizabeth M Tessier, Benjamin L Shneider, Joseph F Petrosino, Geoffrey A Preidis May 2025

Bile Acid And Microbiome Interactions In The Developing Child, Mary Elizabeth M Tessier, Benjamin L Shneider, Joseph F Petrosino, Geoffrey A Preidis

Faculty, Staff and Students Publications

Interactions between the gut microbiome and bile acids are complex and are linked to outcomes in pediatric liver disease by mechanisms that are incompletely understood. In adults, primary bile acids are synthesized in the liver and secreted into the intestine, where complex communities of gut microbes deconjugate, oxidize, epimerize, and 7α-dehydroxylate bile acids into a diverse array of unconjugated, secondary, allo-, iso-, and oxo-bile acids. In contrast, the infant gut microbiota contains a simple, Bifidobacterium-dominant community that transitions to a more diverse, adult-like community as additional microbes colonize the gut. This microbial succession gradually confers deconjugation, oxidation, epimerization, and 7α-dehydroxylation …


First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon May 2025

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon

Biology Faculty Publications

The introduction of non-native fish species in the freshwater ecosystems of the Philippines presents a clear threat to native ichthyofauna, making verified reports of such introductions all the more critical. Through the examination of a collected specimen and anecdotes from fisherfolk and social media, we present here the first records of the occurrence of the tinfoil barb, Barbonymus schwanefeldii (Bleeker, 1854), in Laguna de Bay, Luzon Island, Philippines. This represents the addition of another non-native fish species in this lake, which is increasingly becoming dominated by non-native and invasive fishes that have been intentionally or accidentally introduced. Monitoring landed fish …


Tracing Clovis Landscapes: Chert Sourcing At The Copelin Valley Site In Kentucky., Shaylee Scott May 2025

Tracing Clovis Landscapes: Chert Sourcing At The Copelin Valley Site In Kentucky., Shaylee Scott

Electronic Theses and Dissertations

This study conducts a raw material sourcing analysis of Clovis lithic artifacts from Copelin Valley, Hart County, Kentucky, a key Clovis occupation site. Over a decade of documenting private collections and recent archaeological investigations confirm the site's significance within the Paleoindian landscape. Using reflectance spectroscopy, a non-destructive technique, this research assesses chert source probabilities for over 100 Clovis points and tools. By integrating spectral data with geological sourcing frameworks, this study examines raw material procurement strategies and their implications for Clovis mobility and settlement. The findings reveal patterns in material selection, shedding light on occupation intensity, technological organization, and landscape …


“Souls Cannot Rest In Contested Places”: An Ethnographic Case Study And Archeological Environmental Assessment Of The North Shore Cemeteries., Henrietta K. Ransdell May 2025

“Souls Cannot Rest In Contested Places”: An Ethnographic Case Study And Archeological Environmental Assessment Of The North Shore Cemeteries., Henrietta K. Ransdell

Electronic Theses and Dissertations

This thesis is an ethnographic case study and archeological-environmental assessment of the North Shore Cemeteries to derive condition commentary and care recommendations for the landscape, cultural resources, descendant community, and Great Smoky Mountains National Park. Framed by theories of space-place culture, dispossession, and public lands co-management, this multi-methods, interdisciplinary thesis combines historical context, environmental conditions, archeological documentation, participant observations, and ethnographic interviewing of NPS and community affiliates to derive applied strategies for cemetery repair, operational efficacy, and this specific, public lands “co-management” relationship. With data from 12 interviews, eight participant observations, and six condition assessment surveys, it’s argued that perceptions …


The Dynamic Role Of Hyaluronan In Acute Cardiac Wound Healing., Danielle T. Little May 2025

The Dynamic Role Of Hyaluronan In Acute Cardiac Wound Healing., Danielle T. Little

Electronic Theses and Dissertations

During acute myocardial infarction (MI), the composition of the extracellular matrix (ECM) undergoes significant changes. While collagen accumulation is one of the most well-documented ECM alterations, hyaluronan (HA) is equally abundant. However, the cellular sources, enzymatic regulation, and functional significance of HA accumulation remain largely unexplored. Here, we hypothesized that activated cardiac fibroblasts produce HA via hyaluronan synthase 2 (HAS2), facilitating scar formation and stability. Our findings demonstrate that HA accumulates post-MI and persists for at least four weeks. Through HA sizing techniques, we determined the molecular weight of this persistent HA. Additionally, RNA sequencing analysis of failing human hearts …


Women And Gender Non-Conforming Introductory Stem Students Navigating Gender, Faculty Expectations, And College Support Systems., Trisha A. Douin-Manning May 2025

Women And Gender Non-Conforming Introductory Stem Students Navigating Gender, Faculty Expectations, And College Support Systems., Trisha A. Douin-Manning

Electronic Theses and Dissertations

Women and gender non-conforming students remain underrepresented in Science, Technology, Engineering, and Math (STEM) majors within higher education, and gender disparities persist in advancement to high-paying STEM careers (Maloy et al., 2021; NSF, 2015; Riegle-Crumb et al., 2018). This three-article style dissertation uses qualitative interviews with 29 women and gender non-conforming introductory STEM students and 11 STEM faculty to investigate how these students navigate through their introductory STEM courses. Women and gender non-conforming students in this study faced academic, familial, and gendered pressures to succeed in introductory STEM courses. Many of the students in this study described feelings of oppression …


Teacher Perspectives On A Teacher Mentorship Program And Its Influence On A Sense Of Belonging And Professional Growth., Hyun Kang Wilson May 2025

Teacher Perspectives On A Teacher Mentorship Program And Its Influence On A Sense Of Belonging And Professional Growth., Hyun Kang Wilson

Electronic Theses and Dissertations

Teacher retention is crisis in the U.S. and globally. Literature suggests the first five years of teaching is a crucial time range to determine if teachers stay in the profession or quit. Teachers will leave the profession due to lack of support, poor school culture, feeling isolated, high work-related stress, poor compensation, and challenging student behaviors. Research suggests that new teacher mentorship programs are effective in addressing teacher support, ultimately improving teacher retention. Literature also suggests that employees are more likely to stay with a company if they feel belonged. To explore the further into a new teacher mentorship program …


“Nothing Can Prepare You For It”: An Interpretative Phenomenological Analysis Of The Lived Experiences, Well-Being, And Relational Connections Of First-Time Mothers Navigating Intensive Mothering Ideals And Expectations., Mona A. Dajani May 2025

“Nothing Can Prepare You For It”: An Interpretative Phenomenological Analysis Of The Lived Experiences, Well-Being, And Relational Connections Of First-Time Mothers Navigating Intensive Mothering Ideals And Expectations., Mona A. Dajani

Electronic Theses and Dissertations

Becoming a mother is a life-changing experience that alters how mothers view and experience their emotional, familial, occupational, and relational worlds. As mothering stories tend to be underrepresented and largely absent from the field of social work, this qualitative study utilized Interpretative Phenomenological Analysis (IPA) to center the voices of eleven first-time mothers navigating a culture of intensive mothering ideals and expectations. As a result, the main research questions of this study are: 1) What are the lived experiences of mothers navigating a culture with deep-rooted intensive mothering expectations and ideals? 2) How is well-being experienced and described in the …


The Role Of Tgfβ-Activated Kinase 1 In Fibroblast Differentiation And Cardiac Remodeling After Injury., Daniel Chien Nguyen May 2025

The Role Of Tgfβ-Activated Kinase 1 In Fibroblast Differentiation And Cardiac Remodeling After Injury., Daniel Chien Nguyen

Electronic Theses and Dissertations

Immediately following myocardial injury, a robust reparative response is orchestrated through intercellular communication. While various cell populations play critical roles in this process, cardiac fibroblasts have long been recognized as essential mediators of collagen synthesis and scar maturation; however, recent investigations have uncovered significant heterogeneity within the cardiac fibroblast population, revealing distinct subpopulations with roles that extend beyond their traditional functions. Notably, after tissue injury, fibroblasts exposed to damage signals can transition to an inflammatory phenotype, utilizing paracrine and autocrine signaling to coordinate immune cell recruitment and activation. Yet, the mechanisms underlying inflammatory cardiac fibroblast differentiation and their influence on …


Black Women Under The White Gaze: Resistance From Enslavement To Incarceration And Reentry., Barbie C. Parker May 2025

Black Women Under The White Gaze: Resistance From Enslavement To Incarceration And Reentry., Barbie C. Parker

Electronic Theses and Dissertations

Black women in the United States who are currently incarcerated or have previously served time in prison have a particular need for protection as they move through the criminal “injustice” system because they frequently act as the primary caregivers for their families. Consequently, Black female convicts have historically had to create their social networks inside and outside carceral spaces as a form of resistance to white supremacist ideologies and as a site of protection. By highlighting Black women’s history of enslavement and incarceration, the different forms of resistance, and centering their narratives, we can paint a more complex picture of …


The Impacts Of Management Practices On Industrial Hemp Chemistry, Physiology, And Microbiome Ecology., Allison Marie Rietman May 2025

The Impacts Of Management Practices On Industrial Hemp Chemistry, Physiology, And Microbiome Ecology., Allison Marie Rietman

Electronic Theses and Dissertations

Agroecology incorporates ecology and agronomy to inform crop management. Industrial hemp (Cannabis sativa L.) is a prime system to investigate agroecological questions because it has only recently been authorized for commercial cultivation and its sensitivity to biotic and abiotic stressors is unresolved. Here, I investigate how some conventional management choices, including the application of fungicide, plastic mulch, and irrigation, impact the physiology, chemistry, and microbial ecology of industrial hemp. Overall, I found that industrial hemp can be both resilient and resistant to these stressors, an important development for the industry. In Chapter II, I tested the impacts of fungicide application …


Volatile Organic Compounds And Their Relation To Sympathetic Activation And Autonomic Balance In Humans., Cameron Kyle Stopforth May 2025

Volatile Organic Compounds And Their Relation To Sympathetic Activation And Autonomic Balance In Humans., Cameron Kyle Stopforth

Electronic Theses and Dissertations

Cardiovascular disease (CVD) is a multifaceted pathology that affects almost half of Americans ≥20 years old. One modifiable risk factor associated with CVD is air pollution exposure. The intricacy of air pollution exposure and CVD can make it difficult to elucidate on the multitude of mechanisms underpinning these associations. In this dissertation, we selected a relevant exposure (i.e., volatile organic compounds (VOC)) and an intermediate outcome (i.e., autonomic balance) that may represent one of these pertinent mechanisms. We tested the central hypothesis that higher VOC exposures would lead to increased sympathetic activation and autonomic imbalance. Aim 1 (Chapter III …


What Happens To Soil And Native Plant Life After Removal Of Lonicera Maackii In An Urban Temperate Forest?, Sheryl A. Gipson Hammond May 2025

What Happens To Soil And Native Plant Life After Removal Of Lonicera Maackii In An Urban Temperate Forest?, Sheryl A. Gipson Hammond

Electronic Theses and Dissertations

In evaluating the potential effects of nitrogen cycles and pH on plant diversity and richness after the removal of Lonicera maackii in a temperate urban forest in Louisville, Kentucky, data was collected including nitrogen, pH, canopy, stem count, and plant surveys. The cutting and treatment with chemicals to remove L. maackii were successful one year after the treatments, but legacy effects ensued about five years thereafter. Native diversity waned as monoculture proliferated in some areas, including second invasions of the invasive. It was expected that nitrogen and pH would explain the success (or lack thereof) of native plant response as …


The Effects Of Ethanol And Tributyrin On Alzheimer's Disease Pathogenesis In 3×Tg-Ad Mice., Lucy June Sloan May 2025

The Effects Of Ethanol And Tributyrin On Alzheimer's Disease Pathogenesis In 3×Tg-Ad Mice., Lucy June Sloan

Electronic Theses and Dissertations

Alzheimer’s disease (AD) is a complex progressive neurodegenerative dementia with clinical hallmarks of amyloid-β plaques, hyper-phosphorylated tau in neurofibrillary tangles (NFTs), and neurodegeneration. Chronic, excessive alcohol consumption is associated with an increased risk for developing AD and other dementias. Both AD and chronic alcohol consumption are associated with dysbiosis in the gut microbiome (GM) characterized by a significant loss of beneficial butyrate-producing bacteria within the Firmicutes phylum. Previous studies demonstrate that chronic alcohol consumption accelerates AD pathogenesis in the 3×Tg-AD mouse model and that oral tributyrin (TB) supplementation in 3×Tg-AD mice reduces age-associated GM dysbiosis and AD-associated neurobehavioral deficits and …


Applying Residence Time Distribution Theory To Coronary Thermodilution Curves., Jacob Michael Miller May 2025

Applying Residence Time Distribution Theory To Coronary Thermodilution Curves., Jacob Michael Miller

Electronic Theses and Dissertations

Cardiovascular diseases remain the leading cause of death worldwide and coronary microvascular dysfunction is one cardiovascular disease which is particularly challenging to diagnose and treat. Coronary thermodilution is a widely used, invasive procedure to evaluate microvascular function by generating physiological indices such as coronary flow reserve and the index of microvascular resistance. Although commonly cited as an indicator dilution method in the cardiovascular literature, current coronary thermodilution techniques lack rigorous application of the accompanying mathematical framework, thereby leaving potentially valuable diagnostic information unexploited. This study bridges that gap by demonstrating the equivalence between indicator-dilution theory and residence time distribution theory …


The Impact Of Consensus Decision Making On Creating Conditions For Psychological Safety In Sbdm Councils., Rachel Ann Klein May 2025

The Impact Of Consensus Decision Making On Creating Conditions For Psychological Safety In Sbdm Councils., Rachel Ann Klein

Electronic Theses and Dissertations

This study reflects an examination of the forces and factors that impact effective decision-making on a Site-Based Decision Making council (SBDM) in Kentucky. It explores the relationship between consensus decision-making, the leader of a school, and the stakeholders who sit on an SBDM council as it relates to members’ feelings of inclusion, value, and belonging. A qualitative case study was designed to capture observational data gathered during SBDM meetings, as well as data gathered during member interviews. This data was analyzed through a relativist theoretical lens, which revealed that when open, trusting relationships are established among council members, decision-making flourishes. …


Investigating Mental Health Outcomes Of National Collegiate Athletic Association (Ncaa) Division I Student-Athletes At The University Of Louisville, 2019-2023., Paul Harvey May 2025

Investigating Mental Health Outcomes Of National Collegiate Athletic Association (Ncaa) Division I Student-Athletes At The University Of Louisville, 2019-2023., Paul Harvey

Electronic Theses and Dissertations

Mental health outcomes among collegiate student-athletes, has become a broader concern in the 21st century. This study examines prevalence and incidence of anxiety and depression amongst student-athletes at the University of Louisville from 2019-2023 across different Sports Groups. The prevalence of anxiety was found to be 20.22% and risk of anxiety was 15.65%. The prevalence of depression was found to be 13.11% and risk of depression was 18.75%. Logistic regression was used to estimate the association between sports groups and anxiety/depression. There was a borderline association between sports groups and prevalence of anxiety after confounder adjustment (OR=1.86, 95% CI: …


A Black Sherlock Holmes: An Exploration Of Nonconforming Characterization., Faith Janaye Artis May 2025

A Black Sherlock Holmes: An Exploration Of Nonconforming Characterization., Faith Janaye Artis

Electronic Theses and Dissertations

In the wake of diversity initiatives in the greater American theatre landscape, we are now including more Black actors than ever. Whether that be through the inclusion of diverse playwrights or implementing new casting protocols, we now have Black people in the room. However, when portraying the Black “version” of a character (i.e. Black Annie, Black Ariel, Black Juliet) a question still plagues the Black Actor’s mind: how am I meant to fit here? I evaluate my process of portraying Sherlock Holmes as my thesis role. By challenging the implied white perspective in this “universal” story (despite its feminist retelling), …


Student Perceptions Of School Climate And Safety After The Collective Trauma Of Covid-19 And Racial Injustice Syndemic., Amy Catherine Lyons May 2025

Student Perceptions Of School Climate And Safety After The Collective Trauma Of Covid-19 And Racial Injustice Syndemic., Amy Catherine Lyons

Electronic Theses and Dissertations

For people in marginalized communities, particularly the Black and African American community, the combined, disproportionate damage and loss from of the pandemic and a cacophony of racial injustices offer cause for labeling the phenomenon a syndemic. Syndemic is defined as “a conceptual framework for understanding diseases or health conditions that arise in populations and that are exacerbated by the social, economic, environmental, and political milieu in which a population is immersed” (Singer et al., 2017, p. 881). The purpose of this study is to explore, describe, and analyze Kentucky students’ perceptions of school climate and safety by demographic groups, racial …


Studies Of Pathways To T2d And Interventions Through A Dynamical System Model., Rafiqul Islam May 2025

Studies Of Pathways To T2d And Interventions Through A Dynamical System Model., Rafiqul Islam

Electronic Theses and Dissertations

Existing mathematical models investigating the progression of type 2 diabetes (T2D) over time primarily focus on glucose, insulin, β-cell mass, and other related factors, while often omitting fatty acids (FA) as an explicit variable—despite FA being a major energy source for the body. There exists a complex network of dynamical interactions among glucose, insulin, FA, and β-cell mass. To gain deeper insights into the metabolic dynamics and pathophysiology of T2D, it is essential to incorporate FA into such models. In this study, we extend the classic Topp’s GIβ model by explicitly incorporating FA and exploring its interactions with glucose, insulin, …


Cns-Specific Hiv Reservoir Characterization In Humans: Advancing Our Understanding Through Novel Genomics Methods., Ghazal Sadri May 2025

Cns-Specific Hiv Reservoir Characterization In Humans: Advancing Our Understanding Through Novel Genomics Methods., Ghazal Sadri

Electronic Theses and Dissertations

The persistence of the human immunodeficiency virus (HIV) reservoir despite years of suppressive antiretroviral therapy (ART) represents the principal obstacle to achieving a functional cure. Because the intact, replication-competent portion of the reservoir drives viral rebound after treatment interruption, HIV cure strategies must specifically identify and target cells harboring these proviruses. Conventional reservoir‐characterization techniques typically require separate assays to capture integration sites, assess proviral integrity, and quantify clonal proliferation and they rely on short‐read sequencing. These limitations hinder our ability to understand how integration landscapes, the integrity of the HIV genome, and cell‐division dynamics intersect to maintain viral persistence in …