Digital Commons Network^™

Chemistry Education At The University Of Southern Mississippi Through Computation And Active Learning Methods, Sadie Pitre

Honors Theses

Education is one of the pillars of society. It evolves alongside scientific progress, shaping how students learn and engage with complex topics. The incorporation of new educational standards at The University of Southern Mississippi (USM) was implemented in two parts: through computational chemistry laboratory exercises for teaching laboratories and through the synthesis of organic molecules for research projects in an upper-level spectroscopy class. The goal of these projects is to improve learning of abstract and/or complex topics beyond the teaching methods traditionally utilized in the undergraduate laboratory and in the classroom.

Computational chemistry, which uses theoretical calculations to model molecular …

Smoking And Oral Health In The Tipu Maya: A Study Of Nicotine In Dental Calculus, Emily Byrd

Honors Theses

Tobacco smoking was a deeply rooted tradition in Maya society, often associated with ritual and daily life, and may have contributed to patterns of dental health. However, despite its cultural significance, direct biological evidence of tobacco use in ancient populations is rare. This study addresses that gap by analyzing nicotine residues preserved in dental calculus from the Tipu Maya, offering new insight into both cultural practices and potential health impacts.

Mass spectrometry identified molecular peaks corresponding to nicotine and its degradation products within the calculus samples.  Analysis revealed that over two-thirds of the individuals tested positive for nicotine, supporting the …

Mapping The Path Forward: A Dual Approach Using Ot Assessment & Mentorship To Support The Well-Being Of Youth In Dcf Custody, Kimberly T. Santos

OTD DEx Reports - College of Pharmacy and Health Sciences

This literature review investigates the external relationship needs of foster youth, with particular focus on the prevalence of attachment disorders and trauma-related symptoms resulting from adverse childhood experiences. The Doctoral Experiential (DEx) Capstone Project centers on the development of an occupational therapy-based assessment tool designed to evaluate emotional and environmental safety for youth in residential care. In collaboration with Gandara Mental Health Center and direct care staff, the project also includes the implementation of a training program aimed at enhancing staff understanding of trauma-informed care, youth development, and the role of meaningful mentorship. Foster youth often lack stable, supportive external …

Negotiating Food Security, Maria Cudowska

Journal of Food Law & Policy

In the United States and worldwide, nutrition and food emerge as both high-profile public policy targets and as fundamental aspects of the right to self-determination. This Article examines how national security impacts food security in the United States. It explores conflicts and synergies between municipal, state, and federal law developments related to the right to food and investigates recent developments in how those commitments have been negotiated. The challenge and nebulous justiciability of the right to food can be in part attributed to existing global and national systems, which include supply chains, welfare programs, and foreign investment in the U.S. …

Jtc 25: Inspired To Help Others, Pam Starling

University of Mississippi News

This story is part of the 2025 Journey to Commencement series, which celebrates the pinnacle of the academic year by highlighting University of Mississippi students and their outstanding academic and personal journeys from college student to college graduate.

Which Costimulatory Domains In Chimeric Antigen Receptor T Cells Induce Cytokine Responses That Are Linked To A More Toxic Car T Cell Therapy In Acute Lymphocytic Leukemia?, Elisabeth Cohen

Longwood Senior Thesis Proposal

No abstract provided.

Deciphering And Translating Bioinspired Structures For Engineering Materials Design Via Computational Modeling And Machine Learning, Zhangke Yang

All Dissertations

Nature has evolved extraordinary structural materials—such as nacre, bone, and the mantis shrimp’s dactyl club—that achieve remarkable combinations of strength, toughness, and impact resistance. These properties arise from sophisticated synergies between structure and composition. Inspired by these biological systems, this dissertation presents a comprehensive investigation into bioinspired materials, uncovering fundamental mechanisms and providing guidance on designing materials with superior mechanical properties.

This dissertation begins by examining the "brick-and-mortar" structure of nacre, which informs the design of layered polymer-graphene nanocomposite films. Using coarse-grained molecular dynamics simulations, I elucidate mechanisms of dynamic wave propagation and energy dissipation in these systems, providing critical …

Understanding Dimensional Stability Of Polymer Surgical Mesh, Simeon J. Mckelvey

All Dissertations

Polymer surgical mesh is a biomedical implant that has revolutionized the repair of the abdominal wall and pelvic floor. Each year, over 1.6 million Americans undergo surgical procedures using polymer surgical mesh to treat conditions where internal organs protrude through weakened tissues. This material is used in approximately 90% of hernia repairs, 80% of stress urinary incontinence procedures, and 30% of pelvic organ prolapse surgeries.

Despite this widespread use of polymer surgical mesh, post-implantation complications have prompted regulatory investigation and scrutiny. These complications stem from the mesh's behavior within the human body, including wrinkling, contraction, and loss of fixation, which …

The Interplay Of Housing Instability And Mathematics During Adolescence: A Retrospective Study Of Black Stem Folx, Sharetta M. W. Bufford

All Dissertations

Few studies have delved into the delicate nuances that impact Black students’ mathematics performance, nor have they paid much attention to the resources students leverage to overcome systems that perpetuate negative stereotypes about Black youth. For decades, studies about Black youth have been explored from a deficit perspective, shedding negative light on circumstances typically beyond the control of those being studied. Even more, some studies have placed blame on parents and parental figures in the lives of Black children for unacceptable school behavior and poor academic progress (Cobb II & Russell, 2015). Black youth have been portrayed as problematic, disruptive, …

Associations Between Retinopathy Of Prematurity And The Risks Of Hearing Loss: A Propensity Matched Analysis, Hejin Jeong, Todd Otteson

Student Scholarship

Purpose: While retinopathy of prematurity (ROP) and hearing loss (HL) share many risk factors, whether patients with ROP have a higher risk of HL remains largely unknown. Therefore, this study aimed to explore the association between ROP and the risk of having HL. Methods: The electronic medical records contained in a United States national database were retrospectively reviewed. Patients younger than 18 years old with a record of receiving hearing screening were included. Eligible patients with a history of ROP were assigned to the ROP cohort, while those without ROP diagnosis after vision screening served as controls. After adjusting for …

Global Multi-Specialty Clinician Perspectives On The Implementation Of Alzheimer's Disease Blood Biomarkers, Joanne Rodda, Lindsey A. Kuchenbecker, Wyllians V. Borelli, Mari L. Demarco, Raphael M. Castilhos, Erin E. Cawston, Tinatin Chabrashvili, Melissa M. Budelier, Claudia Duran Aniotz, Chinedu Momoh

Brain and Mind Institute

Introduction: Clinicians' views on the clinical readiness of Alzheimer's disease (AD) blood biomarkers (BBMs) are not well understood.

Methods: The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment Biofluid-Based Biomarkers Professional Interest Area conducted a survey to elicit clinician opinions on AD BBM implementation, including contexts of use, assay selection, reporting, and result interpretation.

Results: Clinician respondents (n = 212) practiced in Europe (56%), North America (24%), the Caribbean and Central/South America (11%), and other continents (9%). Most respondents were medical doctors (80%) practicing in secondary or tertiary care (88%). For 56%, cerebrospinal fluid AD …

California Middle And High School Students Report Wanting Fresh And Healthy School Lunch In The Context Of Universal School Meals, Carolyn Chelius, Kassandra A. Bacon, Dania Orta-Aleman, Monica D. Zuercher, Lorrene D. Ritchie, Juliana Cohen, Christina A. Hecht, Kenneth Hecht, Wendi Gosliner

Health Sciences Faculty Publications

Objective

Design

Setting

Participants

Main Outcome Measure

Analysis

Results

Synthetic Modification Of Agrobacterium To Inhibit Plant Pathogenesis, Rosemala Agarwala

Honors Theses

Crown Gall disease caused by Agrobacterium is a leading cause of plant damage and current solutions used to prevent the disease are not as effective. This research aims to use a synthetic biology approach to design a plasmid that upregulates Curdlan, a molecule that activates plant defenses, when the bacteria senses a wounded plant. Thus this research uses a synthetic biology approach to develop a biocontrol agent for Crown Gall disease. This research also looks at the transferability of the sugar phenol sensing mechanism in Agrobacterium, which is needed for plant pathogenesis.

An Ethical Defense Of Puberty Blockers As Gender Affirming Care For Adolescents, Alexander Konigsberg

Honors Theses

In this paper, I give an overview of the varying perspectives on gender affirming care, which disagree on who has the right to decide for the adolescent. I offer the psychological model as the perspective providers should take to avoid imposing their own morals on the patient. Next, I explore adolescent wellbeing and determine that since no adolescent specific goods exist, we should treat adolescents by child or adult wellbeing if you believe child wellbeing exists). I find that with these arguments, physicians should prescribe puberty blockers to adolescents as it gives more access to wellbeing. Finally, I explore objections …

Substrate Complexity Is Not Correlated With Skin Pattern Complexity In Callistoctopus Furvus, Emily Lekas

Honors Theses

Callistoctopus furvus is an understudied, nocturnal octopus that inhabits shallow, subtropical waters in the western Atlantic. This species relies on camouflage to blend in to diverse environments to escape predators. To understand the relationship between substrate and skin patterning in this species, we used second-by-second analysis of video data recorded in the field. We compared frequencies of four substrate types (sand, rock, algae, and seagrass) ranked by contrast across ten skin patterns displayed by C. furvus. Chi-squared analyses showed significant results that the four substrates were unevenly represented in every skin pattern. However, the data did not support our hypothesis …

Healing On Their Own Terms: Self-Guided Attuning And Mental Health Among Chinese “Youth”, Ziran (Ted) Zhou

Honors Theses

This thesis explores how Chinese “youth” experiencing emotional distress pursue healing outside formal psychiatric frameworks. Drawing on thirteen qualitative interviews and guided by theories from medical anthropology, this study examines how young people engage Traditional Chinese Medicine (TCM) practices and everyday bodily adjustments to manage suffering. Rather than rejecting care altogether, participants turned toward culturally resonant practices that emphasized gradual self-attuning (自我调节, zìwǒ tiáojié) to internal rhythms. Healing was framed not as rupture or diagnosis, but as a relational and moral process: one that preserved emotional dignity, protected family honor, and maintained social harmony. The findings challenge assumptions that psychiatric …

A Multi-Scale Compartmental Model For Glucose Regulation And Diabetes Treatment, Andrew M. Watts

Honors Theses

Glucose is a fundamental energy source for cellular function, and its regulation is critical for maintaining metabolic stability in the human body. Glucose homeostasis is governed by a network of biochemical processes involving multiple organ systems that coordinate glucose production, storage, and uptake. Disruptions in this regulation contribute to metabolic disorders such as diabetes mellitus, underscoring the need for mathematical models that provide a mechanistic understanding of systemic glucose dynamics. Herein, we report a multi-time scale discrete-time dynamical systems model using compartmental difference equations to describe glucose concentrations across key physiological compartments. By quantitatively modeling glucose transport and metabolism, this …

Dean's Research Newsletter, May 2025, Neil W. Schluger

SOM Dean's Research Newsletter

No abstract provided.

Deviant Trajectories Of Black Girls In Adolescent Romantic Relationships, Anna I. Fondren

All Dissertations

This quantitative study explored whether involvement in adolescent romantic relationships among Black females influenced juvenile delinquency and later criminal behavior. While prior research has examined how peers, family, and romantic partners impact delinquency and substance use, the unique intersection of being both Black and female in this context remains underexplored. The study used data from the National Longitudinal Study of Adolescent to Adult Health (Add Health), which follows U.S. adolescents from middle and high school into adulthood (ages 24–32). The dataset included variables related to peer and family relationships, romantic and sexual involvement, substance use, victimization, delinquency, and criminal behavior. …

Patulin As A Negative Regulator Of Wild-Type Elp1 Splicing In Familial Dysautonomia-Derived Cells, Katherine P. Cáceres Bravo

FCRH Honors Program Theses

Although the human genome has a limited number of genes, alternative splicing allows the production of thousands of proteins. Alternative splicing is a regulated mechanism in which a messenger RNA (mRNA) synthesizes different proteins called isoforms, variants of the same protein that may have different cellular functions [1]. The unspliced sequence, also known as the primary transcript, results from the transcription of a genetic sequence by RNA Polymerase II, which produces an mRNA containing introns (non-coding regions) and exons (coding regions) [2]. The splicing process is catalyzed by the spliceosome, a ribonucleoprotein mega-particle composed of small nuclear ribonucleoproteins (snRNPs), U1, …

The Narrative Effects Of Cure On Representations Of Disability In The Medical Procedural And Body Horror Genres, Will Schuessler

FCRH Honors Program Theses

In disability studies, “cure” can refer both to literal cures and to the cultural belief that disabilities are problems with the body that can and should be solved through these medical interventions. In recent years, disability scholars have written about this topic of cure critically, but an academic media analysis approach to cure has yet to be taken, despite the prevalence of narratives where disabled characters are cured. This thesis explores how cure shapes disabled stories that are told through film and television, by viewing a sample of over 50 films and 70 episodes of television focused on disabled characters …

Optimum Volume Of Serious Fluid For The Detection Of Malignancy: A Systematic Review, Sarah Atieno Okech

Master of Medicine in Anatomic Pathology

No abstract provided.

Assessing The Effect Of Prolonged Saltwater Exposure On Dna Recovery In Submerged Skeletal Remains From Sus Scrofa Domesticus (Erxleben, 1777), Malia Wellens

Master's Theses

Both water-related and mass disasters occurring over or in water (e.g., boating disasters, commercial plane crashes, and natural disasters) result in multiple deaths every year. Due to the ocean's vastness and lack of equipment, remains may not be recovered for some time, resulting in soft tissue decomposition, leaving bone as the last repository of recoverable DNA for identification purposes. Skeletal remains' physical and chemical components protect them from environmental deterioration and biological attack and preserve DNA well. Therefore, identifying an individual may depend on DNA obtained from skeletal remains. However, there is limited research on how long DNA can be …

From Guns To Scalpels: Reproductive Violence And The (In)Visibility Of Non-Lethal Genocidal Acts, Anthony Ghaly

Vanderbilt Journal of Transnational Law

No abstract provided.

The Distribution Of Spinal Cord Injury Severity Across Age And Injury Location In Frontal Impact Automobile Collisions, Alyssa Teixeira

Master's Theses

Automobile collisions are a leading cause of spinal cord injuries (SCIs) worldwide, accounting for about 42% of SCIs in the United States alone (McDonald & Sadowsky, 2002; Roberts et al., 2017). The World Health Organization (WHO) identifies road traffic injuries as the leading cause of death for individuals aged 5-29 years, emphasizing the urgent need for effective prevention strategies (World Health Organization, 2023). The primary aim of this study was to identify differences in spinal column injury severity and location (cervical, thoracic, or lumbar) across multiple age groups to identify any discrepancies or similarities. A total of 302 traffic accidents …

Medical Device Sterilization As A Public Health Paradox, Paradise, Jordan

Santa Clara Law Review

Medical device sterilization processes are a public health paradox. Sterility is necessary to assure product safety, yet emissions from the most common form of industrial sterilization, ethylene oxide (EtO), cause cancer. The connection between ethylene oxide and health risks has existed for decades, though recent litigation, state legislation, and advocacy efforts have illuminated the risks. This Article explores the large-scale EtO emissions in Willowbrook, Illinois caused by a facility run by Sterigenics, a corporate entity with facilities across the United States. The Sterigenics case study will be utilized to examine the scope of adverse health and environmental effects; the local, …

Assessing Chatgpt's Capability As A New Age Standardized Patient: Qualitative Study, Joseph Cross, Tarron Kayalackakom, Raymond E. Robinson, Andrea Vaughans, Roopa Sebastian, Ricardo Hood, Courtney Lewis, Sumanth Devaraju, Prasanna Honnavar, Nikhilesh Anand

School of Medicine Publications

Background: Standardized patients (SPs) have been crucial in medical education, offering realistic patient interactions to students. Despite their benefits, SP training is resource-intensive and access can be limited. Advances in artificial intelligence (AI), particularly with large language models such as ChatGPT, present new opportunities for virtual SPs, potentially addressing these limitations.

Objectives: This study aims to assess medical students' perceptions and experiences of using ChatGPT as an SP and to evaluate ChatGPT's effectiveness in performing as a virtual SP in a medical school setting.

Methods: This qualitative study, approved by the American University of Antigua Institutional Review Board, involved 9 …

Introducing Social Determinants Of Health To The Alzheimer's Disease Research Center Network: Development And Implementation In The Uniform Data Set, Megan Zuelsdorff, Erin L. Abner, Joyce E. Balls-Berry, Gregory A. Jicha, Serggio Lanata, Gladys Maestre, Monica Rosselli, Shana D. Stites, Rachel A. Whitmer, Consuelo H. Wilkins

School of Medicine Publications

The Alzheimer's Disease Research Centers (ADRCs) consortium represents a critical locus of research on Alzheimer's disease and related disorders (ADRD) prevention, diagnosis, and intervention. Through the National Alzheimer's Coordinating Center's (NACC) standardized protocol, the Uniform Data Set (UDS), ADRCs have collected rich, harmonizable clinical and cognitive data. However, the collection of social data has been sparse and Center specific, constraining ADRD science that addresses research priorities on social determinants of health (SDOH) and health equity. Capitalizing on the transition to a revised UDS version 4, an interdisciplinary committee representing 10 ADRCs reviewed the literature and instrumentation, ultimately creating a brief …

A Bishnoi Woman’S Odhani: Gendered Labor, Environmental Ethics, And Textile Traditions In Rajasthan, Nidhi Patel

Department of Anthropology

This report examines an embroidered odhani (woman’s shawl) attributed to a Bishnoi artisan from Rajasthan, India. The odhani is housed in the May Weber Ethnographic Study Collection at Loyola University Chicago. Close analysis of technique and contextual evidence is used to reattribute the textile, which was originally mislabeled and situates it within the contexts of gendered labor and environmental ethics within the Bishnoi community. Utilizing the frameworks of materialist and eco-spiritual feminism, the report argues that the odhani functions as a site of ecological resistance, cultural transmission, and women’s embodied knowledge, as well as a garment.

Development And Validation Of An Adolescent Sleep Algorithm For Pediatric Primary Care, Holly Hink

Doctoral Scholarly Projects & Capstones

Poor sleep quality is a common challenge for many adolescents due to various developmental, environmental, and social factors. Nearly half of all adolescents reported regularly experiencing sleep disruptions. Poor sleep quality among adolescents might have severe mental, emotional, and cognitive consequences including an increased risk for several psychiatric conditions, obesity, and poor academic performance. However, sleep disorders among this population frequently go unreported and are rarely screened during annual well-child exams with primary care providers. The purpose of this project was to develop an evidence-based sleep algorithm for pediatric primary care providers designed to improve screening and treatment of adolescent …