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Human Activity Recognition And Identification Driven Automated Deep Learning For Time-Series Classification, Justin Alan Gamble

Engineering Management & Systems Engineering Theses & Dissertations

The growing emphasis on Digital Engineering (DE) within the U.S. Department of Defense (DoD) demands advanced methods for leveraging vast time-series data generated by sensor-rich environments. Deep learning models offer promising solutions for complex timeseries classification tasks, however their design and optimization remain highly resource intensive, requiring specialized expertise. This dissertation addresses this challenge by developing and evaluating an Automated Machine Learning (AutoML) framework specifically tailored for the time-series classification task of Human Activity Recognition and Identification (HARI).

A systematic investigation was conducted using the Design Science Research Methodology (DSRM) comparing traditional search strategies of grid search and random search …

The Inside Scoop: Elucidating The Three-Way Relationship Between Schistosoma Mansoni, The Gut, And Vaccines, Mariam A. Mhanna

Biomedical Sciences Theses & Dissertations

Schistosomiasis is a neglected tropical disease that affects over 250 million people worldwide. This blood fluke infection burdens communities and areas with limited to no access to clean fresh water. When a host is exposed to cercariae, the infectious agent, in a body of water, it matures in the host’s circulation into adult female and male worms. Copulated adult worms migrate to the mesentery, in the case of Schistosoma mansoni, and produce eggs that can cross the intestinal barrier and get excreted in the feces to continue the lifecycle. The effects of S. mansoni infection on the host …

Biojardineras In Monteverde: A Mixed Method Approach To Examine Greywater Treatment, Elyssa Allen, Jackson Anderson, Brayden Dostal, Alan Hernandez, Kacy Moe, Facundo Pereya-Kluser

Monteverde Institute: Tropical Ecology and Conservation

Rural and semi-rural regions around the globe often struggle with inadequate wastewater treatment infrastructure, thereby negatively impacting the public and environmental health of the region. Due to its rural nature and current infrastructure, the Monteverde Zone (MVZ) in Costa Rica lacks a centralized wastewater system, with many homes relying on septic tanks for wastewater treatment. To prevent overloaded flows to septic tanks, greywater from kitchens, laundry, showers, and sinks is often discharged separately to the environment with no treatment. This pollutes the surrounding water bodies and streets with pathogens, soap, excess nutrients, as well as fats, oils, and grease (FOG). …

The Lived Experiences Of Fathers With Postpartum Depression: A Qualitative Study, Rachael Elizabeth Schmitz

Nursing and Health Sciences

Background:

Although parents may joyfully anticipate the birth of a child, it's impossible for them to know ahead of time just how profoundly their lives will change. Postpartum depression (PPD) can result. While there is a substantial body of research regarding maternal PPD, paternal PPD has received far less attention and is neither adequately understood nor diagnosed. This is exacerbated by outdated but persistent sociocultural masculinity norms and the stigmas around mental health issues.

Purpose:

This study sought to explore the lived experiences of new fathers with PPD in order to provide greater insight into their experiences.

Methods:

This qualitative …

Identifying And Examining Stressors In The Secondary And Post-Secondary Classroom, Benjamin S. Alter

All NMU Master's Theses

Students in secondary and post-secondary classrooms are openly exposed to stressors that can be considered impactful in their day-to-day lives.These stressors can be categorized as either “positive,” which serve as motivators, or “negative,” which often cause anxiety. In order to understand the stressors that students experience, students in a rural teacher education program at Northern Michigan University were asked to respond anonymously to a survey asking about stressors at the secondary and post-secondary levels. The survey was given to students enrolled in the Winter & Fall semesters of 2023, and the Winter semester of 2024. Students identified stressors from their …

The Effect Of An Acute Bout Of Rock Climbing On Cognitive Functioning And Cortisol Levels, Vanessa Steigauf

All NMU Master's Theses

Rock climbing is an understudied physical activity (PA) that demands active decision-making, integration of sensory and visual input, and continuous regulation of nervous system activity to produce complex motor outputs. The unique psychological demands of climbing warrant studying its effect on cognition and brain health. I recruited 26 generally healthy adults for a randomized-controlled study. Climbing experience, PA and perceived stress were self-reported. Each participant was randomly assigned to a climbing (10x2 minutes climb, moderate intensity) or control group (seated, watching climbing-related video). The primary outcomes, cognitive performance and salivary cortisol levels were assessed by the Stroop test. A linear …

Opportunistic Short-Term Water Uptake Dynamics By Subalpine Trees Observed Via In Situ Water Isotope Measurements, Matthias Sprenger, Stefan Seeger, Max Berkelhammer, Nathaniel A. Bogie, Raymond J. Hess, Wendy S. Brown, Sylvain Kuppel, James Knighton

Faculty Research, Scholarly, and Creative Activity

Variations in tree water sources are important to understand in semi-arid ecosystems because climatic shifts towards lower snowpack and increased drought affect water availability in subalpine forests of the western US. Here, we use daily in situ measurements of stable isotopes (²H & ¹⁸O) in soil and tree stem water, soil matric potential and sap flow to study tree water uptake dynamics. We instrumented three soil profiles down to 90 cm, as well as three aspen and engelmann spruce trees near Gothic, Colorado, in the East River watershed. We observed the fate of natural isotopic variations in …

Mathematical Modeling Of Effects Of Tumor Location On Lung Function., Lamargaret Temukisa Johnson

Master of Engineering Theses

Lung cancer has the highest rates of incidence and mortality of all cancers. Most lung cancer tumors are Non-Small Cell Lung Cancer (NSCLC). NSCLC patients with lesions in the upper lobes are found to have better prognosis compared to those with lesions in the middle and lower lobes. Previous studies have suggested various causes for this discrepancy at both the organ-scale and tissue-scale. To model NSCLC growth in different locations within the lung, an organ scale lung model and tissue scale tumor model were coupled through the tissue pressure, and oxygen and carbon dioxide partial pressures. The coupling was used …

Enhancing Postpartum Depression Screening Rates: An Educational Intervention For Primary Care Pediatric Providers: A Quality Improvement Project, Jasmine Shaterra Jones

Doctor of Nursing Practice Projects

This quality improvement (QI) project sought to increase postpartum depression (PPD) screening rates at a single pediatric primary care practice setting by implementing an educational intervention for pediatric providers. Postpartum depression is a common and debilitating mental health condition affecting many mothers worldwide. Postpartum depression impacts many women in the United States and affects all ethnicities, although rates may vary based on demographic and socioeconomic factors. Despite the American Academy of Pediatrics' recommendations for maternal PPD screening at one, two, four, and six months, well-child visits, national screening rates remain low, with a large number of cases undiagnosed. The current …

Climate Drives Genetic Diversity Loss In American Pika (Ochotona Princeps) Populations In The Great Basin, Emily N. Kulig, Jane Van Gunst, Michael J. Hernandez, Yvonne Luong, Monica Villaseñor, Rachel S. Crowhurst, Clinton W. Epps, Jessica A.Castillo Vardaro

Faculty Research, Scholarly, and Creative Activity

American pikas (Ochotona princeps) are small, thermally sensitive mammals that primarily live in montane and alpine environments. The Sierra Nevada lineage (O. p. schisticeps) has experienced numerous local extinctions, most of which occurred in hotter, drier regions such as the Great Basin. Few genetic studies have assessed these at-risk populations. This study aims to fill that gap by conducting fine-scale genetic analyses on populations in low-elevation Great Basin habitat in northwestern Nevada. Specifically, we: (i) quantified genetic diversity and structure among populations within O. p schisticeps, with particular focus on northwestern Nevada; and (ii) assessed the influence of primary productivity …

Exploring Variability Of The Cg18562578 Methylquant Assay For The Forensic Discrimination Of Monozygotic Twins, Sydney E. Arnold

Student Theses

Monozygotic (MZ) twins possess identical DNA sequences, posing a problem for forensic scientists, as they are incapable of distinguishing MZ twins from each other using traditional DNA identification methods. However, the epigenomes of MZ twins will differ and might be used for their forensic discrimination. Here, we explored the variability of an assay previously developed by our laboratory that showed high discrimination potential for MZ twins using buccal swab DNA, cg18562578 MethylQuant. We measured precision at each step: bisulfite conversion, nested PCR, and qPCR, reproducibility, and repeatability. DNA methylation ratios were compared between two analysts carrying each step using the …

Cg18562578 Methylquant Assay For The Discrimination Of Monozygotic Twins, Amber P. Chauca

Student Theses

Monozygotic (MZ) twins have identical DNA, making traditional profiling methods insufficient in their discrimination. However, MZ twins can be differentiated by their levels of DNA methylation. Our research group previously developed a methodology to detect cg18562578 DNA methylation levels in MZ twins based on a two- step PCR approach and a cg18562578 MethylQuant Assay. That study generated data for only 64% of the samples it investigated, and showed a discrimination power of 77% to discriminate between MZ twins. Here, we used the same methodology but a different approach to determine DNA methylation in 73 previously unsuccessful twin pairs. We diluted …

Further Investigation Of Environmental Factors On Rapid Shear In Fibers Of A Polyester-Cotton Blend, Daniel K. Oh

Student Theses

Rapid shear is a process that occurs in thermoplastic materials when they interact with a high-velocity impact. In forensics, these interactions would typically be from a bullet interacting with clothing that consisted of synthetic fibers. When the interaction occurs, bulb-like shapes appear on damaged fiber ends, distinguishing them from other kinds of damage. The reason why these shapes occur is varied, but one prevailing factor seems to be the heat generated by the impact.

In prior experiments, the factor of temperature being important to the formation of the phenomenon, different environmental simulations that affected the sample’s temperature were done on …

Prevalence And Risk Factors Of Gastroesophageal Reflux Disease Among Population Of Saudi Arabia: A Meta-Analysis, Waleed D. Khubzan, Dana O. Kaddah, Ola E. Alkhoshiban, Mirza H. Alkhater, Botool A. Alshahrani, Rama A. Alhatlani, Muntaha S. Alsulaimani, Dalal A. Elyas, Majed A. Almourgi

Saudi Medical Journal

ABSTRACT Objectives: To find how common gastroesophageal reflux disease (GERD) is in Saudi Arabia and to identify the main risk factors linked to it. Methods: We followed PRISMA guidelines and registered the study on PROSPERO (CRD42025637142). A full literature search was done across PubMed, MEDLINE, and Google Scholar up to December 2024. Two reviewers independently reviewed the results. We assessed the risk of bias using the JBI critical appraisal tool and evaluated potential reporting bias through Egger’s test. To determine the overall prevalence and key contributing risk factors, we conducted a meta-analysis utilizing a random-effects approach. We also did subgroup …

Unified Mathematical Modeling, Analysis And Simulation Of Covid-19 And Ecological Processes, Jacob Derrick

Masters Theses and Doctoral Dissertations

This dissertation is concerned with the modeling, simulation, and analysis of complex population dynamics using compartmental modeling frameworks based on ordinary differential equations (ODEs). First, we propose a mechanistic model to investigate the transmission dynamics of COVID-19, particularly focusing on the emergence and population-level impact of a post-acute sequela referred to as long COVID and vaccination effects. We then move forward with a model that incorporates multiple strains and reinfection dynamics. By fitting these models to epidemiological data from the United States and the United Kingdom, we conduct both mathematical analyses and numerical simulations to better understand the factors driving …

A Brief Cognitive-Behavioral Intervention For Emotion Regulationand Aggression In Justice-Involved Adolescents: Preliminary Outcomes From A Non-Randomized Trial In Short-Term Juvenile Detention, Cassidy L. Tennity

Dissertations

Justice-involved youth are at risk for a variety of psychosocial difficulties, including anger, aggression, and emotion regulation challenges. Short-term juvenile detention settings offer a unique opportunity to provide psychological interventions to youth before they are returned to the community or sentenced to long-term placements. However, implementation barriers within these settings often hinder the delivery of evidence-based care. This study developed and tested a brief, two-session anger management intervention for adolescents detained in a short-term juvenile detention center in the Southeastern United States, drawing on evidence-based practices from prior work with justice-involved youth. The present study examined implementation outcomes (i.e., feasibility, …

The Impact Of Gender, Training Year, Medical Specialty And The Covid-19 Pandemic On Resident Wellness, Sara Beachy, Jessica Luzier, Chantel Weisenmuller, Kathleen Bors, Mary Ann Maurer, Amna Anees, Tiffany Lasky, Lisa Calderwood

Department of Family & Community Medicine Faculty Papers

INTRODUCTION: Data are limited as to which factors most strongly impact medical trainees' well-being, and few studies have assessed trainee's wellness at multiple time points during the COVID-19 pandemic. Additionally, much research has not taken an intersectional approach to understanding the ways in which different facets of a resident's identity impact their wellness. Thus, more person-centred, probability-driven statistical approaches that can produce distinct heterogenous groups of individuals are warranted to understand the way in which different identities are associated with resident wellness scores.

METHODS: A latent profile analysis was conducted using institutional data from resident surveys administered from 2019 to …

Optimal Hypergraph Connectivity With Cut Queries, Hang Liao

Dartmouth College Ph.D Dissertations

Finding connected components in undirected hypergraphs—hypergraph connectivity—is a fundamental problem in computer science. It can be framed as a special case of Symmetric Submodular Function Minimization (SSFM), where the objective is to determine if the non-trivial minimizer is zero. This thesis develops an optimal algorithm for hypergraph connectivity within the $\CUT$ query model, where an algorithm probes a subset of vertices to learn the weight of the hyperedges ``cut" by that partition.

Our approach is constructive, culminating in an optimal algorithm for the general problem by first developing the necessary tools for two foundational subproblems. The main contributions of this …

Exploring Intra- And Interpersonal Connection Through Mindful Moments At A Hispanic-Serving Institution, Yvette Angeline

Theses and Dissertations

The demands of contemporary education have contributed to high levels of stress, anxiety, and burnout among educators (Barton, 2019; Hidajat et al., 2023; Walker, 2022), uncovering a need for pedagogical approaches that prioritize holistic well-being and humanize the learning experience (Palmer, 2009; Salazar, 2013; Wong & Mishra, 2020). This qualitative case study investigates how moments of mindfulness, integrated as curricular practice within a teacher education program at a Hispanic-Serving Institution (HSI), nurtures pre-service teachers’ awareness of the self and world. This study explores aspects of mindfulness from its Eastern origins (Thich Nhat Hanh, 1975) and its Western secular applications (Jon …

Assessment Of Floral Resources From Three Tamaulipan Thornscrub Communities Of The Lower Rio Grande Valley, Gracie Makenna Granados

Theses and Dissertations

The Tamaulipan thornscrub is a transition zone between the neotropics and the temperate regions, harboring high biodiversity. This habitat supports a diverse insect community, including many pollinators of native and cultivated plants in Texas and northeastern Mexico. This ecosystem has been extensively degraded and lost; only 5% of its original cover remains north of the Rio Grande. Restoration of the Tamaulipan thornscrub has been ongoing for over three decades, but the important roles of pollinators in the success of such efforts and the functioning of the restored ecosystem have rarely been considered in restoration efforts. The purpose of this study …

Bilateral Leading Edges With Tubercle Modifications: An Experimental Study, Roberto Sanchez

Theses and Dissertations

The increasing demand for better performance and maneuverability from airfoils to sustain superior performance over a wide range of platforms, including vehicles, propellers, and wing designs, continues to grow. Researchers have drawn inspiration from nature, looking at birds of prey, dragonflies, and humpback whales for aerodynamic improvements. Among these, tubercle airfoils, inspired by the humpback whale’s flipper, have gained increasing interest. This experimental study presents the results of bilateral tubercle leading-edge airfoils based on a modified NACA 0018 design with a chord length of 1.82 inches, a span width of 7.5 inches, and an amplitude of 6.3c%. Five configurations were …

Development Of A Wearable Biosensor For Cortisol Detection In Human Sweat Utilizing Pani/Peo Polymer Blend And Nitrogen-Doped Graphene Quantum Dots, Cesar Sanchez

Theses and Dissertations

Since the development of the first biosensor in 1962, the evolution of commercially available wearable biosensors has been driven by an increasing consumer interest in real-time health tracking. However, challenges related to sensor sensitivity and cost have hindered progress. Deploying a novel approach, the biosensor integrates a blend of Polyaniline (PANi) and Polyethylene Oxide (PEO) along with Nitrogen-doped Graphene Quantum Dots (N-GQDs) to enhance sensitivity and electroactivity, crucial for cortisol detection. To optimize performance, three distinct synthesis methods for N-GQDs; hydrothermal, microwave, and hot plate synthesis were compared employing a bottom-up approach utilizing citric acid (CA) as the primary reactant …

The Impact Of Positive Psychology Use Upon Gls Outcomes For People With Chronic Pain Syndromes, Timothy Michael Curtis

Theses and Dissertations

The essence of being human is realized by our discovery of meaningful purpose throughout each important stage of our lives. If we perceive that we lack this meaningful purpose in our lives, it could become a distressful source of suffering to our sense of well-being emotionally, cognitively and perhaps, spiritually. A strong indicator of well-being comes from a good evaluation we ascertain as to how well we believe outcomes in our lives are consistent with our goals and values, which is also known as satisfaction with life. Research findings indicate that the more someone experiences repeated negative life events, the …

Arginine Vasotocin And Corticosterone In Nesting And Non-Nesting Loggerhead Sea Turtles In X’Cacel-X’Cacelito Sanctuary, Krista Blair Reed

Theses and Dissertations

Sea turtles exhibit distinct behaviors before and after egg laying, however, not all individuals successfully oviposit. Some females display disruptions in their typical nesting behavior, returning to the water without laying eggs, which is referred to as a non-nesting emergence (NNE). NNEs can be due to external disturbances on the beach, but why they occur is often unclear. Arginine vasotocin (AVT) is a neuropeptide involved in various physiological processes, including stimulating smooth muscle contraction of the oviduct to facilitate egg deposition in nesting sea turtles. On the other hand, corticosterone is the primary stress hormone in sea turtles and is …

Exploring Transcriptional Stress Responses In Sorghum And Evolutionary Insights Into Yth Domain Proteins Across Plants, Shikha Bharti

Theses and Dissertations

Understanding how plants respond to abiotic stress is crucial for enhancing crop resilience in the face of climate change. This thesis explores plant stress adaptation mechanisms through two interlinked studies that address different aspects of gene regulation. The first study investigates the transcriptional dynamics of Sorghum bicolor under drought and heat stress at 1-hour and 6-hour time points. By employing 3'-end RNA sequencing, this study provides a comprehensive temporal view of gene expression changes, revealing stress-responsive transcription factors, hormone-associated pathways, and chromatin regulators. The comparative analysis highlights both common and distinct molecular responses between drought and heat stress, providing insights …

Biological, Histological, And Immunohistochemical Responses To Heat Stress In Common Goldfish, Carassius Auratus, Ngozichukwu Francis Ngozichukwu

Theses and Dissertations

Global climate change has led to rising temperatures, posing significant challenges to aquatic ecosystems and the health of ectothermic species such as goldfish (Carassius auratus) This thesis investigated the effects of heat stress on growth performance, histological alterations, and molecular stress responses in the gill and kidney tissues of goldfish Fish were exposed to control (24°C), medium (28°C), and high (32°C) temperatures for two weeks Growth parameters, including instantaneous growth rate (IGR), absolute growth rate (AGR), body value gain (BVG), and condition factor, were evaluated alongside histological and immunohistochemical markers of stress Results revealed that high temperature significantly reduced AGR …

Analyzing How Taste And Nutrition Impact Learning And Memory In Honey Bees Through Olfactory Associative Conditioning, Alessandra Elizabeth Perry

Theses and Dissertations

Honey bees detect sweet nectar, but not all sweet-tasting sugars provide nutrition. Unlike fruit flies, which can learn to avoid non-nutritious sweet foods, bees may lack this ability. To test if bees form caloric frustration memory (CFM), we conditioned them using odors paired with L-glucose (sweet but non-nutritious) or D-glucose (sweet and nutritious). Bees rewarded with L-glucose showed lower learning and long-term memory compared to D-glucose. Bees cannot differentiate between an odor associated with rewards containing malaise-causing compounds and an odor associated with a reward alone during differential conditioning. Therefore, we used differential conditioning to determine if lower acquisition in …

Transcriptomic Study On The Effect Of Salt Stress In Sorghum Bicolor Seedlings, Joshwa A. Gandy

Theses and Dissertations

The global impact and reliance on cereal crops, and sorghum in particular, is paramount for worldwide food security and for the livelihood of hundreds of millions of people. The detrimental effects of salt stress on crop plants and the huge economic losses it causes by affecting agricultural output worldwide is a devastating issue with huge impacts, which have prompted research to combat salinity in numerous ways. Understanding how cereals respond to the negative effects of salt stress is crucial for enhancing their salt tolerance. In this study of sorghum, we used a 3’-end RNA sequencing approach to elucidate major salt …

Interdigitated Gear-Shaped Screen-Printed Electrode Using G-Pani Ink For Sensitive Electrochemical Detection Of Stress Related Hormones Dopamine And Cortisol, Pritu Parna Sarkar

Theses and Dissertations

This research introduces a novel interdigitated gear-shaped graphene-based electrochemical biosensor for the simultaneous detection of dopamine (DA) and cortisol. Modified with graphene–polyaniline (G–PANI) conductive ink, the sensor increased active surface area—94.52% and 57% higher than Metrohm DropSens 110 and circular printed sensors, respectively. Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) Spectroscopy and X-ray diffraction (XRD) were employed for physicochemical characterization. The sensor detects dopamine and cortisol over a linear range of 0.1–100 µM, with limits of detection of 0.043 µM (R² = 0.98) and 0.0577 µg/mL (R² = 0.976), respectively, in phosphate-buffered saline (PBS) using redox probe. Electrochemical performance …

Opa1-Mediated Mitochondrial Dynamics In Myogenic Differentiation Of C2c12 Myoblasts, Daniel Eloy Bazan

Theses and Dissertations

Mitochondria play a pivotal role in metabolic energy production, cellular signaling, and apoptosis. To carry out these key cellular roles, mitochondria dynamically balance their organization through opposing including fusion and fission processes. The balance between mitochondrial fusion and fission is regulated by key proteins such as OPA1 (optic atrophy 1) and OMA1 (overlapping activity with metalloprotease). More recently, mitochondria have been increasingly revealed to play key roles in cellular differentiation, where metabolic demands are reprogrammed. This study aims to elucidate the specific roles of OPA1 and OMA1 in the differentiation of C2C12 myoblast cells into myotubes.

Our data demonstrates that …