Digital Commons Network^™

Incidence Of And Risk Factors For Hyperoxemia Among Potentially Critically Ill Patients Treated In The Wards: A Retrospective Study, Mehmet Nuri̇ Yakar, Doğukan Şenberber, Ozan Balkabak, Nurgazy Shermatov, Kaan Köşker, Seli̇n Elden, Emel İbi̇şoğlu, Begüm Ergan, Volkan Hanci, Necati̇ Gökmen

Turkish Journal of Medical Sciences

Background/aim: The literature shows a link between hyperoxemia and poor outcomes, whereas this association remains unclear in hospital wards. This study aims to determine the incidence of hyperoxemia in hospital wards and its risk factors.

Materials and methods: Patients aged ≥ 18 years who underwent an evaluation by an intensivist between 1 January 2020 and 31 December 2020, while receiving treatment in hospital wards, were included in the study following ethics committee approval. Patients with hypoxemia (partial pressure of oxygen [PaO2] < 60 mmHg), a condition related to Coronavirus disease 2019, a hospital stay < 1 day, or missing data were excluded. Patients were divided into two groups: normoxemia (60 mmHg ≤ PaO2 < 120 mmHg) and hyperoxemia.

Results: The incidence of hyperoxemia was 42.2%. Patients with hyperoxemia had longer hospital stays and higher intensive care unit …

Prognostic Role Of Systemic Immune-Inflammation Index And Pan-Immune-Inflammation Value In Acute Methanol Poisoning, Hati̇ce Şahi̇n, Gülay Ulusal Okyay, Fatma Ayerden Ebi̇nç, Fevzi̇ Coşkun Sökmen, Emre Yaşar, Gülşen Akçay, Mehmet Deni̇z Ayli

Turkish Journal of Medical Sciences

Background/aim: Acute methanol poisoning (MP) poses a significant public health challenge, with inflammation increasingly recognized as a key factor in its pathophysiology. Identifying accessible and reliable prognostic biomarkers could help enhance clinical outcomes. This study aimed to assess the prognostic value of the Systemic Immune-Inflammation Index (SII) and the Pan-Immune-Inflammation Value (PIV), measured upon emergency department admission, in predicting in-hospital mortality in patients with acute MP.Material and methods: This retrospective study included patients diagnosed with acute MP at two tertiary care centers in Ankara, Türkiye [University of Health Sciences Dışkapı Yıldırım Beyazıt Education and Research Hospital (January 1, 2015–October 1, …

Comparison Of Novel Diard-Hbv Dna Qpcr Kit With The Artus Hbv Qs-Rgq Kit For Quantification Of Hbv Dna In Clinical Samples, Ülker Çuhaci, Hande Toptan, Bengül Durmaz, Mehmet Köroğlu, Riza Durmaz

Turkish Journal of Medical Sciences

Background/aim: Hepatitis B virus (HBV) leads to widespread chronic infections that may result in long-term complications such as cirrhosis and hepatocellular carcinoma. The use of sensitive molecular methods for HBV DNA quantitation has provided significant contributions for diagnosis and monitoring of disease. The current study aimed to evaluate the diagnostic performances of a novel DiaRD HBV qPCR kit (novel kit) in comparison with the artus HBV QS-RGQ kit (comparator kit).

Materials and methods: A total of 288 plasma samples—105 HBV DNA-positive and 183 HBV DNA-negative—were tested using both kits. The diagnostic and quantitative results of the novel kit were compared …

Mirna-Target Gene Network Analysis In Siblings With Cystic Fibrosis And Phenotypic Variability, Ayberk Mustafaoğlu, Senem Noyan, Yeli̇z Z. Akkaya Ulum, Bala Gür Dedeoğlu, Nagehan Emi̇rali̇oğlu, Uğur Özçeli̇k, Ebru Yalçin, Deni̇z Doğru, Nural Ki̇per, Di̇dem Dayangaç Erden

Turkish Journal of Medical Sciences

Background/aim: Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CF is characterized by respiratory tract infections, pancreatic insufficiency, meconium ileus, intestinal obstruction, and male infertility. A genotype to phenotype correlation is difficult to establish because of the heterogeneity of disease severity. Even patients with the same CFTR mutation can have varying clinical severities. In recent years, studies have explored the role of microRNA (miRNA) expression in the regulation of respiratory diseases. However, no research has been conducted to date on miRNAs in siblings with the same CFTR mutation. …

Metabolic And Genotypic Characterization Of Meropenem Susceptible And Resistant Serratia Marcescens Isolates, Şeyma Ni̇gi̇z, Gülşen Hazirolan, Gülşen Altinkanat Gelmez, Ceren Özkul Koçak, Engi̇n Koçak, Sevi̇lay Erdoğan Kablan, Emi̇rhan Nemutlu, Aycan Gündoğdu, Fatma Bayrakdar, Ufuk Hasdemi̇r, Deni̇z Gür

Turkish Journal of Medical Sciences

Background/aim: Serratia marcescens which is a nosocomial pathogen, is naturally resistant to a wide spectrum of antibiotics, which makes the management of infections difficult. The aim of this study was to determine the in vitro susceptibilities of S. marcescens to ceftriaxone, ceftazidime, meropenem, amikacin, gentamicin, ciprofloxacin, and to compare the metabolic profiles of meropenemresistant isolates under basal conditions and after exposure to sublethal concentrations of meropenem.

Materials and methods: A total of 84 S. marcescens isolates were included from various samples. Genes for meropenem resistance were determined by polymerase chain reaction (PCR). Genetic similarities among isolates of S. marcescens were …

Letter To The Editor Regarding “Kılıçarslan A, Kurt Çevik G, Doğan M, Aksoy Altınboğa A, Ceran F, Et Al. Does Cd47 Expression Have Prognostic Significance In Classical Hodgkin Lymphoma? Turkish Journal Of Medical Sciences: 2025; 55 (1): 22”, Burcu Baba, Ayşegül Akbay

Turkish Journal of Medical Sciences

No abstract provided.

The Impact Of The Doctor-Patient Relationship In Bipoc Women Suffering From Benign Gynecological Conditions, Gabriela Baez

Seton Hall University Dissertations and Theses (ETDs)

This study sought to gain a better understanding of the impact of the doctor-patient relationship on BIPOC women with benign gynecological conditions. The current study explored how wellbeing is impacted in BIPOC cis-gender women with benign gynecological conditions by measuring the quality of the relationship. General racism experience was also explored as a moderator on the impact of doctor-patient relationship on wellbeing. A total of 169 participant responses were included in this study. Hierarchical regression analysis demonstrated that there was a significant relationship between gynecological conditions and wellbeing. In addition, there was a significant negative relationship between racism experience and …

Sexual Intervention Self-Efficacy In Clinical And Counseling Psychology Doctoral Trainees: Examining Education, Family Sexual Communication, And Sex Positivity, Sara Aigen

Seton Hall University Dissertations and Theses (ETDs)

Sexual wellbeing is a critical yet often overlooked aspect of psychological health. Despite its significance, many psychologists report discomfort and low self-efficacy in addressing clients’ sexual concerns. The current study examined factors associated with sexual intervention self-efficacy among doctoral trainees in clinical and counseling psychology. Specifically, it investigated whether family communication about sex and didactic education in sexuality predicted sexual intervention self-efficacy and whether sex positivity moderated these relationships. A cross-sectional survey design was employed with 166 doctoral students enrolled in APA-accredited programs across the United States. Participants completed a demographic questionnaire and measures assessing family sexual communication, sex positivity, …

Transcriptomic And Epigenomic Profiling Of Immune Cells Responses To Simian Immunodeficiency Virus Infection In The Brain, Xiaoke Xu

Theses & Dissertations

Human immunodeficiency virus type 1 (HIV-1) is an enveloped retrovirus that significantly impairs the human immune system. A common complication of HIV-1 infection is HIV-associated neurocognitive disorder (HAND), which, prior to the introduction of antiretroviral therapy (ART), led to considerable morbidity and mortality due to untreated neuropsychiatric manifestations. Although ART has substantially reduced the incidence of HIV-associated dementia (HAD), approximately 50% of people living with HIV (PLWH) continue to experience milder forms of HAND. The CNS is seeded by HIV during the acute phase of infection. Once in the brain, HIV targets and activates resident immune cells, primarily microglia and …

Morphology, Evolution And Host-Driven Convergence In Ichneumonidae (Hymenoptera, Ichneumonoidea), Davide Dal Pos

Graduate Thesis and Dissertation post-2024

Understanding the functional and evolutionary significance of morphology is fundamental to interpreting the tree of life. In recent years, emerging tools have enabled broad-scale analysis of discrete morphological data and facilitated the study of entire phenomes, helping to re-establish morphology as a central component of evolutionary research. These advances allow us not only to examine individual traits in detail but also to compare them across taxa and explore their evolutionary trajectories. This approach is particularly critical when studying hyperdiverse groups that exhibit both high levels of morphological convergence and complex life cycles intricately tied to host use. A prime example …

Marine Ecosystem Services Disruption And Social Violence, Rafael Hurtado-Valdivieso

Graduate Thesis and Dissertation post-2024

Over the past century, human activities have profoundly altered ocean and coastal ecosystems, significantly impacting communities whose livelihoods depend on these environments. This dissertation explores how disruptions in marine ecosystem services contribute to the emergence of social violence in coastal communities, with a specific focus on the Colombian Caribbean. While prior research suggests a potential link between environmental degradation and conflict, empirical evidence remains limited and inconclusive. This study addresses that gap through a multi-method, interdisciplinary approach that integrates environmental science, political science, and computational modeling to examine the mechanisms linking ecosystem disruption to social violence.

The research follows a …

Bridging Data Gaps And Forecasting Challenges In Water Quality Monitoring Using Deep Learning, Rohan Gudla

Graduate Thesis and Dissertation post-2024

Reliable water quality monitoring is critical for protecting public health and enabling sustainable environmental management. However, high rates of missing data often exceed 40% due to sensor failures and operational disruptions severely undermine the utility of environmental monitoring systems. To address this challenge, this thesis presents a three-stage deep learning framework designed to enhance the accuracy and resilience of water quality forecasting. First, a Bidirectional Long Short-Term Memory model with Attention and Autoencoder Modules (BiLSTM-AAM) is introduced to impute long, irregular gaps in multivariate time series. Applied to real-world data from the St. Lucie River Basin, the model achieved a …

Computational Approaches For Rna Structural Motif Analysis: Similarities, Variations, And Spatial Relationships, Md Mahfuzur Rahaman

Graduate Thesis and Dissertation post-2024

The three-dimensional structures of RNA play a critical role in understanding their functions. One way to study the RNA 3D structure is by analyzing recurrent segments within the loop regions of RNAs, known as RNA structural motifs. These motifs can be grouped into families based on their structural features. However, the inherent structural diversity presents challenges in characterizing the similarities, variations, and spatial relationships within RNA motif families. This dissertation presents three computational methods that together provide a comprehensive framework for RNA structural motif analysis. First, RNAMotifComp establishes and visualizes relational networks among structural motif families. By analyzing instances of …

"Please Hold Space For Them": The Role Of Mental Health Professionals In Supporting Bipoc Female Survivors Of Campus Sexual Assault, Brianna Josefine Ortega

Doctoral Dissertations

Campus sexual assault (CSA) remains a pervasive issue in the United States, disproportionately affecting women. Despite this, the experiences of Black, Indigenous, and other Persons of Color (BIPOC) women are often underrepresented in the literature, limiting understanding of how best to support them. Based on intersectionality theory, this qualitative study explores how mental health professionals (MHPs) support BIPOC female survivors of CSA. Semi-structured interviews were conducted with six MHPs, and a thematic analysis framework uncovered seven key themes: disclosure (subtheme: barriers to disclosure), impacts of campus culture, fear and distrust, impact of campus sexual assault, coping, resources available for survivors, …

The Association Between The Social Determinants Of Health And Shared Decision Making: An Investigation Of The National Survey Of Children's Health, Vernon T. Headley

Graduate Thesis and Dissertation post-2024

Objective: Shared decision-making (SDM) is defined as a clinical approach that allows both physicians and patients to communicate on the best treatment options that will improve the patient's overall health outcomes. Shared decision-making plays a vital role in how parents engage with their physicians regarding the healthcare needs of their children. This dissertation assessed the association between the social determinants of health and shared decision-making regarding children’s health-related issues.

Methods: The data for the current research were the National Survey of Children’s Health (NSCH), combined 2017-2020. The dependent variable was shared decision-making and included discussing treatment options, raising concerns regarding …

Nueva Metodología De Análisis Para Determinar El Delito Ambiental De Ecocidio Por Glifosato En Cultivos Permanentes De Coca En Colombia, Rosalina González Forero, Jerry H. Kavouras, Érika González Ruiz

Biology Department Faculty Articles

El crimen organizado transnacional ha sido nefasto para el territorio colombiano, en especial el asociado a la producción de coca en la última década, lo que ha generado impactos económicos y sociales debido al aumento del conflicto e inseguridad en las zonas de influencia del cultivo. Esto se debe a que en el 2023 se tenían 230 000 hectáreas sembradas, lo que representa el 20 % de la superficie del país, con un impacto ambiental no cuantificado en términos penales. Este requiere de acciones de entidades estatales, así como de cooperación internacional, para adaptar estrategias y poder judicializar estos delitos …

A Comparative Subnational Policy Analysis Of State Covid-19 Vaccine Policies And Application Of The Political Determinants Of Health Model, Demetrius Cianci Chapman

Nursing ETDs

A COMPARATIVE SUBNATIONAL POLICY ANALYSIS OF STATE COVID-19 VACCINE POLICIES AND APPLICATION OF THE POLITICAL DETERMINANTS OF HEALTH MODEL

By

Demetrius Cianci Chapman

Associate of Science Nursing, Jewish Hospital College of Nursing and Allied Health, 1998

Bachelor of Science of Nursing, Saint Louis University, 2000

Master of Public Health, Saint Louis University, 2004

Master of Science Nursing (Research), Saint Louis University, 2004

Doctor of Philosophy, Nursing, University of New Mexico, 2025

ABSTRACT

This study uses the political determinants of health (PDoH) framework to analyze state-level COVID-19 vaccine policies and their impact on population health. The PDoH model examines how structured …

Multimodal Characterization Of Systems-Level Robustness In The Cellular Organelle Network, Aline Arra

Arts & Sciences Graduate Student Theses and Dissertations

Eukaryotic cells house mesoscopic and macroscopic complex systems that work in tandem for proper cellular function. A defining feature of eukaryotic cells is their mesoscopic network of membrane bound compartments called organelles. While each type of organelle has their own individual functions, there are vital cellular processes that come from the interactions between them, such as organelle biogenesis and metabolic regulation. A central question in cellular biophysics is to what degree is cellular function robust or fragile to breaks in the organelle network. These interactions can be explored by genetically deleting inter-organelle protein tethers called organelle contact sites. Here we …

Diverse Cell Types Establish A Pathogenic Immune Environment In Peripheral Neuropathy, Julie Choi

Arts & Sciences Graduate Student Theses and Dissertations

Neuroinflammation plays a complex and context-dependent role in many neurodegenerative diseases. We identified a key pathogenic function of macrophages in a mouse model of a rare human congenital neuropathy in which SARM1, the central executioner of axon degeneration, is activated by hypomorphic mutations in the axon survival factor NMNAT2. Macrophage depletion blocked and reversed neuropathic phenotypes in this sarmopathy model, revealing SARM1-dependent neuroimmune mechanisms as key drivers of disease pathogenesis. In this study, we investigated the impact of chronic subacute SARM1 activation on the peripheral nerve milieu using single cell/nucleus RNA-sequencing (sc/snRNA-seq). Our analyses reveal an expansion of immune cells …

Structure And Function Of Type 1 Pilus Assembly Machinery In Uropathogenic Escherichia Coli, Ryan Bitter

Arts & Sciences Graduate Student Theses and Dissertations

Gram-negative bacteria produce chaperone-usher pathway (CUP) pili, which are extracellular adhesive protein fibers critical for host-pathogen interactions. An outer-membrane usher protein, together with a periplasmic chaperone, assembles thousands of pilin subunits into a pilus fiber. Each pilus is tipped by an adhesin that mediates host and tissue tropisms by binding to receptors with stereochemical specificity. Type 1 pili expressed by uropathogenic Escherichia coli (UPEC) are essential virulence factors in urinary tract infections (UTIs) and facilitate attachment to mannosylated glycoproteins on bladder epithelial cells. Although type 1 pili have been extensively studied, critical gaps remain in our understanding of the molecular …

From Sim To 6dof: Deep Learning For Real-Time Satellite Pose Estimation From Resolved Ground-Based Imagery, Thomas W.N. Dickinson

Theses

This dissertation presents the first practical system for automated six degrees of freedom (6DOF) satellite pose estimation from resolved ground-based adaptive optics (AO) imagery. Addressing a key challenge in Space Domain Awareness (SDA), the proposed approach eliminates the need for human labeling by directly regressing satellite orientation and position from blurry, noisy, and deeply-shadowed imagery. The architecture consists of a multi-stage deep neural network pipeline that localizes the satellite, predicts pose, and optionally smooths predictions over time. Networks are trained exclusively on fully synthetic imagery generated from a 3D CAD model. Despite this, the model generalizes effectively, bridging the Sim2Real …

Flowing Progress: Transforming The Danube Through Infrastructure, Stefan Dorondel, Luminita Gatejel

Central European Studies

Flowing Progress: Transforming the Danube Through Infrastructure focuses on how different political regimes and forms of governance have imagined and technologically transformed the most international river in the world. Multidisciplinary and drawing on methodologies of history, anthropology of infrastructure, and science, technology, and society, this collection explores the tensions between the river and its natural pulses, the humans that populate its floodplains, state agencies, and infrastructure. The book engages the concept of disturbance to point out the circular and spiraling dynamics between hydrological processes and technopolitical and economic practices. Disturbance denotes a specific type of long-term dynamic between human attempts …

Professional Portfolio, Grace E. Lowder

Graduate Student Portfolios, Professional Papers, and Capstone Projects

No abstract provided.

Normal And Reverse Flow Injection- Spectrophotometric Determination Of Doxycycline Hyclate In Bulk And Pharmaceutical Samples, Tabarak Mohammed, Hind Hadi

Baghdad Science Journal

The present paper reports the development and validation of an analytical method for doxycycline hyclate (DOX) quantification in pure and dosage forms by normal and reverse flow injection analysis (FIA) techniques. Two types of FIA approaches were employed to automate a diazotization coupling reaction of DOX with diazotized benzidine dihydrochloride. Red azo dye was formed rapidly and measured at maximum wavelength of 488 nm. Calibration curves were prepared over different DOX concentrations with linearity ranges of 10-250 and 1-180 µg/mL for normal and reverse FIA systems respectively with the limits of detection of 2.95 and 0.46 µg/mL and limits of …

Synthesis, Characterization, Biological Activity And Antioxidant Studies Of New Metal Ion Complexes Based On (E)-4-((Benzo[D]Thiazol-2-Ylimino)Methyl)-1,5-Dimethyl-2-Phenylpyrazolidin-3-One, Rafah Saad Talib, Naser Shaalan

Baghdad Science Journal

The study involved synthesis of four new complexes involving bidentate ligand [(E)-4-((benzo[d]thiazol-2-ylimino) methyl)-1,5-dimethyl-2-phenylpyrazolidin-3-one] with the general formula [M(L)₂Cl₂].xH₂O or [MLCl₂]. xH₂O, where M represents Mn²⁺, Co²⁺, Ni²⁺ and Cu²⁺. The ligand was synthesized by treating the 4-Antipyrinecarboxaldehyde and 2-aminobenzothiazoles in an alcoholic solution. The structural characteristics of ligand and complexes were characterized quantitatively and qualitatively by using various techniques including elemental analyses, magnetic susceptibility measurement, molar conductivity, infrared, ultraviolet absorption, Gc-Mass, and ¹H-NMR spectroscopy studies. The physical measurements indicated that the prepared …

Ability Of Staphylococcus Epidermidis And Escherichia Coli To Eliminate Cadmium, Lead And Copper From Tigris River In Mosul City, May A. Abdul Kader, Ghada A. Mohammad

Baghdad Science Journal

The heavy metals are non-biodegradable and could be toxic and carcinogenic, thus, their improper concentration in water could result in critical health issues for living organisms. Therefore, this study aimed to remove three heavy metals (Cadmium, lead and copper) by biological treatment especially using environmental nonpathogenic bacteria such as Staphylococcus epidermidis and Escherichia coli. Eight samples were collected from Tigris River from different regions of Mosul city. Two containers were used for each sample to measure the concentration of minerals before and after treatment by bacteria. The results showed that E. coli was more efficient in removing two heavy …

Nitrogen Fertilizer Equivalence Of Red Clover When Inter-Seeded Into Corn, Hannah R. Francis, Ting Fung Ma, Rodrigo Werle, Chelsea H. Zegler, Daniel H. Smith, Douglas J. Soldat, Erika Marin-Spiotta, Matthew D. Ruark

Faculty Publications

Inter-seeding red clover (Trifolium pratense L.) provides an alternative method toincorporate cover crops into continuous corn (Zea mays L.) in the Upper US Midwest. Red clover is a leguminous cover crop that can grow in low-radiation environments and is winter hardy. Systems with red clover have demonstrated improved corn yield and a fertilizer N equivalence but understanding these effects with inter-seeding war-rants further investigation. The objectives of this study were to determine the effect of inter-seeding red clover on (i) plant-available N during and after red clover decomposition, (ii) optimum N rates for corn, and (iii) corn yields. The …

Nitrogen Fertilizer Equivalence Of Red Clover When Inter-Seeded Into Corn, Hannah R. Francis, Ting Fung Ma, Rodrigo Werle, Chelsea H. Zegler, Daniel H. Smith, Douglas J. Soldat, Erika Marin-Spiotta, Matthew D. Ruark

Faculty Publications

Inter-seeding red clover (Trifolium pratense L.) provides an alternative method to incorporate cover crops into continuous corn (Zea mays L.) in the Upper US Midwest. Red clover is a leguminous cover crop that can grow in low-radiation environments and is winter hardy. Systems with red clover have demonstrated improved corn yield and a fertilizer N equivalence but understanding these effects with inter-seeding warrants further investigation. The objectives of this study were to determine the effect of inter-seeding red clover on (i) plant-available N during and after red clover decomposition, (ii) optimum N rates for corn, and (iii) corn …

Master Of Social Work Portfolio, Julia Volner

Graduate Student Portfolios, Professional Papers, and Capstone Projects

No abstract provided.

Msw Portfolio, Julia Marie Sweeney

Graduate Student Portfolios, Professional Papers, and Capstone Projects

This portfolio reflects my personal and professional growth throughout the University of Montana’s MSW program. Grounded in lived experience, child advocacy work, and academic learning, it highlights my development across core competencies and advanced integrated practice.