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Pilot Fatigue And Required Rest Period For Korean Air Force Pilots Flying High-Performance Aircraft, Mijin Hong Aug 2025

Pilot Fatigue And Required Rest Period For Korean Air Force Pilots Flying High-Performance Aircraft, Mijin Hong

Graduate Thesis and Dissertation post-2024

Over the years, significant advancements have been made in aircraft technology and in understanding the detrimental effects of fatigue on flight performance. However, integrating these advancements into crew rest regulations, particularly for the Republic of Korea Air Force (ROKAF) operating high-performance jets, requires further review. This study employs a systematic review with thematic analysis to assess whether ROKAF’s current rest regulations are sufficient. Relevant studies were identified from English-language databases (e.g., FAA, ICAO, Google Scholar) and Korean-language databases (e.g., RISS, KCI). Titles and abstracts were initially reviewed, followed by full-text assessments based on inclusion and exclusion criteria focusing on military …


Tail-Imbalance Diffusion Equalizer For Class-Balanced Generation, Chinmay Dhanraj Nehate Aug 2025

Tail-Imbalance Diffusion Equalizer For Class-Balanced Generation, Chinmay Dhanraj Nehate

Graduate Thesis and Dissertation post-2024

Real-world image corpora are often imbalanced. On long-tailed datasets, the head class can outnumber the tail by a large margin, and a vanilla diffusion probabilistic model (DPM) consequently loses fidelity and diversity on rare categories, undermining controllable generation. To address this gap, we present Tail Imbalance Diffusion Equalizer (TIDE), a training framework that restores class balance without discarding data or adding extra training stages. Our contribution is threefold: (i) score field rebalancing, where we embed class-prior knowledge into a mixing matrix that routes gradients toward minority classes, with this class-prior knowledge consisting of the empirical label frequencies in the training …


Sex Estimation Using Linear And Geometric Morphometric Analyses Of The Adult Human Talus, Melissa N. Marks Aug 2025

Sex Estimation Using Linear And Geometric Morphometric Analyses Of The Adult Human Talus, Melissa N. Marks

Graduate Thesis and Dissertation post-2024

Estimating biological sex is an essential first step when analyzing human remains in both forensic and archaeological contexts. While the pelvis and skull are traditionally used for this purpose, they are not always present or sufficiently preserved to permit analysis. The talus is sexually dimorphic and can yield highly accurate sex estimates, making it a promising alternative skeletal element for sex estimation. As there is currently no accepted protocol for sex estimation using the talus, the present study attempts to replicate and validate existing methods using linear and three-dimensional landmark data, while comparing data from ancient Maya (n=16), ancient Egyptian …


Differential Interferon Synthesis And Signaling Between Parainfluenza Virus Acute And Persistently Infected Cells, Vonisha Kaigler Aug 2025

Differential Interferon Synthesis And Signaling Between Parainfluenza Virus Acute And Persistently Infected Cells, Vonisha Kaigler

Graduate Thesis and Dissertation post-2024

RNA virus infections can transition from an initial acute infection to a prolonged or persistent infection, in which infected cells survive and continue to produce progeny virus. This presents a major clinical problem as persistently infected (PI) cells extend viral shedding, maintain inflammation, and provide potential sources for new viral variants. The RNA virus, Parainfluenza virus 5 (PIV5), with mutations in the P/V gene region (P/V mutant) is a strong inducer of antiviral responses. Interestingly, over time, there is an emergence of cells that survive as P/V mutant PI cells. Given that changes in innate immune signaling pathways can occur …


'How To Mother': Televisual Reimaginings Of Black Matriarchy In The Real Housewives Of Potomac, Kalijah Rahming Aug 2025

'How To Mother': Televisual Reimaginings Of Black Matriarchy In The Real Housewives Of Potomac, Kalijah Rahming

Graduate Thesis and Dissertation post-2024

Since the initial launch of The Real Housewives of Orange County in 2006, Bravo’s The Real Housewives franchise has soared to previously unimaginable heights. With 11 American installments, 30 international adaptations, and 25 current spin-offs, it is clear that even viewers who are relatively unfamiliar with The Real Housewives franchise may find themselves inadvertently swept up in their world due to the popularization of their catchphrases and gifs on social media platforms like Instagram, Twitter, and Facebook. In addition to carefully shaping popular culture, members of this franchise have even altered the conditions of the entertainment industry’s practices for the …


A Forgotten Kairos: Rhetorical Memory In 16th Century Europe, Phillip Martin Aug 2025

A Forgotten Kairos: Rhetorical Memory In 16th Century Europe, Phillip Martin

Graduate Thesis and Dissertation post-2024

In 16th century Europe the nearly 2000-year-old discipline of rhetoric, still a pillar of education, underwent significant change. One of the more curious changes occurred in rhetoric’s subdivision known as memory, memoria, that is, memory’s “artificial” cultivation. During the 16th century rhetorical memory was paradoxically both maximized and marginalized as a discipline. And by the early 17th century memoria was all but extinct as a branch of rhetoric. The causal mechanisms of this transformation remain underexamined, particularly by rhetoric and composition scholars, and most explanations remain unclear and uncompelling. Accordingly, this thesis attempts a new approach …


The Impact Of Alternatives To Incarceration And The Motherhood Identity On Mothers And Their Children: A Qualitative Study, Chloe Blau Aug 2025

The Impact Of Alternatives To Incarceration And The Motherhood Identity On Mothers And Their Children: A Qualitative Study, Chloe Blau

Seton Hall University Dissertations and Theses (ETDs)

The U.S. prison system population increasingly includes women, a significant proportion of whom are mothers, often incarcerated for non-violent crimes. Some research suggests that alternative to incarceration (ATI) programs can help these women to continue supporting their children while serving their sentences and receiving services that may decrease recidivism. However, few studies have explored the lived experiences of women in these programs. This dissertation investigates the impact of participating in ATI programs on mothers and their relationship to their motherhood identity, their ability to mother, and their relationship with their children. Using a qualitative approach to better understand how women …


A Thematic Analysis Of The Perceived Impact Of Nil Policy On Athletic Identity, Career Maturity, And Black Male Student-Athletes’ Experience Of Transitioning Away From Football, Jesse Merise Aug 2025

A Thematic Analysis Of The Perceived Impact Of Nil Policy On Athletic Identity, Career Maturity, And Black Male Student-Athletes’ Experience Of Transitioning Away From Football, Jesse Merise

Seton Hall University Dissertations and Theses (ETDs)

In 2007 the NCAA launched the widely recognized slogan, “There are over 380,000 student-athletes, and most of us will go pro in something other than sports.” Today, that figure has risen to over 540,000 and continues grow. Among them, Black male student-athletes (BMSAs) comprise 40% of collegiate football participation across all three divisions, a notable increase from 36% in 2012. Since only a small percentage of college football players go on to play professionally, it means that a large number of Black student-athletes will eventually have to leave sports and pursue other career paths.

This study examined the perceived impact …


A Community-Based Wellness Program To Increase Exercise Adherence For Menopausal And Postmenopausal Women: A Mixed-Methods Pilot Study, Kristin M. Badillo Aug 2025

A Community-Based Wellness Program To Increase Exercise Adherence For Menopausal And Postmenopausal Women: A Mixed-Methods Pilot Study, Kristin M. Badillo

Graduate Thesis and Dissertation post-2024

Evidence exists that long-term commitment to an exercise routine is beneficial. Contrarily, there is a notable lack in exercise adherence among menopausal and postmenopausal women. Though research has thoroughly examined the reasons why menopausal and postmenopausal women may not be committed to an exercise routine, it remains unclear what motivates those who are adherent. This pilot study employed a mixed-methods design through administering surveys and conducting in-person focus group interviews. Additionally, an 8-week buddy system was implemented to assess the role of social support and its effect on exercise adherence. For quantitative data collection, a total of 7 participants enrolled …


Predicting Past And Future Anthropogenic Global Harvest And Land Use, Michelle Bardales Cruz Aug 2025

Predicting Past And Future Anthropogenic Global Harvest And Land Use, Michelle Bardales Cruz

Graduate Thesis and Dissertation post-2024

Anthropogenic appropriation of natural lands has long sustained human populations and activities. Human use of the environment has resulted in the degradation of green spaces and depletion of natural, particularly plant-based, resources. Human appropriation of net primary production (HANPP) is a globally available, spatially explicit measure of this human-driven extraction and diversion of plant biomass through harvesting (HANPPharv) and land use change (HANPPluc). Models for HANPP have been limited temporally (e.g., a year) or in terms of complexity (e.g., one predictor). In this study, I predict HANPPharv and HANPPluc from 1960 to 2010 at …


Student-Athlete Vs Athlete-Student: Differences In Athletic Retirement Expectations, Terrie L. Bradshaw Aug 2025

Student-Athlete Vs Athlete-Student: Differences In Athletic Retirement Expectations, Terrie L. Bradshaw

Graduate Thesis and Dissertation post-2024

The purpose of this qualitative, phenomenological Dissertation in Practice was to define the terms student-athletes and athlete-student by discovering any differences in non-cognitive variables between the two groups. Additionally, this study attempted to identify any differences in career transition expectations between student-athletes and athlete-students. Thirteen NCAA athletes from various universities across the United States were included. With the use of one-on-one semi structured interviews, five themes emerged. The themes that emerged were 1) Both types of athletes attend college for different reasons. 2) Differences in level of commitment. 3) Both types of athletes strive for academic success. 4) Different expectations …


Instructional And Motivational Factors Predicting Deep Learning Approaches In Pre-Clinical Medical Students, Kenneth L. Dearman Aug 2025

Instructional And Motivational Factors Predicting Deep Learning Approaches In Pre-Clinical Medical Students, Kenneth L. Dearman

Graduate Thesis and Dissertation post-2024

Pre-clinical medical students predominantly employ surface learning approaches, focusing on memorization and exam preparation rather than developing a deep understanding of medical knowledge. This study employed a correlational design comparing two courses with different instructional approaches using expectancy-value theory to examine how instructional methods and motivational factors predict deep learning approaches among 148 pre-clinical medical students at a College of Medicine in the Southeastern United States. Initial results showed that the three separate constructs in task motivation (expectancy beliefs, values, and cost) did not mediate the relationship between active instructional methods and deep learning strategies. Instead, active learning was a …


Investigating The Role Of Selenium-Dependent Stickland Reactions In Clostridioides Difficile Bioenergetics, Dominika Dzurny Aug 2025

Investigating The Role Of Selenium-Dependent Stickland Reactions In Clostridioides Difficile Bioenergetics, Dominika Dzurny

Graduate Thesis and Dissertation post-2024

Clostridioides difficile is an anaerobic, spore-forming bacterium and one of the leading causes of antibiotic- associated diarrhea. Colonization depends on the metabolism of certain nutrients in the host gut, namely amino acids and carbohydrates. C. difficile ferments amino acids as an integral part of its metabolism via Stickland reactions, utilizing the selenoproteins D-proline reductase (Prd) and glycine reductase (Grd) to generate energy. Specificity of selenocysteine incorporation reflects the intracellular levels of selenophosphate, the activated selenium donor synthesized by selenophosphate synthetase (SelD). SelD is coincidentally a selenoprotein itself, containing a UGA codon at position 17 (Sec-17). The functional and physiological importance …


Interactions Of Anti-Viral Ceria Nanoparticles With An Enveloped Rna Virus, Muhammad Hassan Mehmood Kalyar Aug 2025

Interactions Of Anti-Viral Ceria Nanoparticles With An Enveloped Rna Virus, Muhammad Hassan Mehmood Kalyar

Graduate Thesis and Dissertation post-2024

There is growing interest in developing durable and broad-spectrum antiviral nanomaterials for surface disinfection. Silver-modified ceria nanoparticles (AgCNPs) are regenerative materials capable of inactivating a wide range of viruses through generation of reactive oxygen species (ROS). We hypothesized that for enveloped RNA viruses, the lipid bilayer and viral spike glycoproteins are determinants of sensitivity to inactivation of infectivity by AgCNPs. This hypothesis was tested using Vesicular Stomatitis Virus (VSV), a model enveloped negative-sense single strand RNA virus containing a single spike glycoprotein G. Five rounds of serial passage of VSV in the presence of suboptimal AgCNP concentrations led to the …


Exploring The Role Of Fatty Acid Signaling In Macrophages, Ayomide Ogunsanmi Aug 2025

Exploring The Role Of Fatty Acid Signaling In Macrophages, Ayomide Ogunsanmi

Graduate Thesis and Dissertation post-2024

Dietary fatty acids play critical roles in both the gustatory and immune systems. In taste, they serve as the sapid molecules that underlie the ability to taste fat, whereas in the immune system, they serve as messengers that help facilitate the fuel-based reprogramming of macrophages (MΦ) that underlie optimal immune function. It has become clear in recent years that there is a functional interaction between the taste and immune system, and fatty acid signaling pathways serve as one focus of this overlap. Similar to taste receptor cells (TRCs), MΦ express G protein-coupled fatty acid receptors GPR120 and GPR84, and our …


Techno-Enviro-Economic Approach For Electrification Of Rural And Shrimp Farming Regional Development Of An Isolated Island In Indonesia By Utilizing Hybrid Renewable Energy Systems, Fiqih Akbar Wijaya, Mohammad Akita Indianto Aug 2025

Techno-Enviro-Economic Approach For Electrification Of Rural And Shrimp Farming Regional Development Of An Isolated Island In Indonesia By Utilizing Hybrid Renewable Energy Systems, Fiqih Akbar Wijaya, Mohammad Akita Indianto

Journal of Materials Exploration and Findings

One of the challenges in developing and archipelagic countries such as Indonesia is maintaining energy demand in rural and isolated areas due to difficulties in electrical distribution. For instance, in areas like Bawean Island, no additional electricity capacity has been introduced in the past year, leading to an unmet potential customer demand. One of the possible options is by utilizing Hybrid Renewable Energy Systems (HRES) that are integrated with existing fossil fuel-based energy systems to support the growing energy demand in the remote island. A case study in Bawean Island is conducted with the projected energy demand covers the energy …


Sinapic Acid Alleviates Renal Ischemia-Reperfusion Injury By Regulating Oxidative Stress, Apoptosis, And Inflammation, Mustafa Can Güler, Fazi̇le Nur Eki̇nci̇ Akdemi̇r, Ersen Eraslan, Ayhan Tanyeli̇, Derya Güzel Erdoğan, Behzat Tebri̇zi̇ Aug 2025

Sinapic Acid Alleviates Renal Ischemia-Reperfusion Injury By Regulating Oxidative Stress, Apoptosis, And Inflammation, Mustafa Can Güler, Fazi̇le Nur Eki̇nci̇ Akdemi̇r, Ersen Eraslan, Ayhan Tanyeli̇, Derya Güzel Erdoğan, Behzat Tebri̇zi̇

Turkish Journal of Medical Sciences

Background/aim: Acute kidney injury (AKI) is a major clinical issue, frequently resulting from ischemia-reperfusion (I/R) injury. Sinapic acid (SA), a natural phenolic molecule included in numerous plant-based foods, exhibits antiapoptotic, antioxidant, and antiinflammatory properties. This study aimed to investigate the renoprotective effects of SA in an I/R-induced acute kidney injury (AKI) model.

Materials and methods: Sprague–Dawley male rats (n = 32) were randomly assigned to four groups: sham, I/R, SA 20 mg/kg, and SA 40 mg/kg. SA was administered intraperitoneally before reperfusion. Renal tissues were examined using biochemical, histopathological, and immunohistochemical methods, focusing on oxidative stress, cytokine expression, and apoptosis …


Analysis Of Leak Testing Planning For Carbon Dioxide Piping Systems In The Development Of Carbon Capture, Utilization, And Storage Facilities In The Bintuni Basin, Devi Sentiani, Akhmad Herman Yuwono Professor Aug 2025

Analysis Of Leak Testing Planning For Carbon Dioxide Piping Systems In The Development Of Carbon Capture, Utilization, And Storage Facilities In The Bintuni Basin, Devi Sentiani, Akhmad Herman Yuwono Professor

Journal of Materials Exploration and Findings

Carbon Capture, Utilization, and Storage (CCUS) technologies have become a key strategic response to global efforts to reduce CO2 emissions. This study presents a leak testing strategy designed for a carbon dioxide (CO₂) piping system as part of a Carbon Capture, Utilization, and Storage (CCUS) project in the Bintuni Basin, West Papua, Indonesia. This study aims to ensure the system is properly prepared before commissioning by designing a leak test plan that is both practical and technical, based on ASME B31.3, ASME PCC-2, and API STD 520 Part 1. We conducted the process, which involves identifying the system boundaries, …


Chromatographic Developments For The Analysis Of Toxic Organic Chemicals In The Environment And Food Samples, Stephanie Devi Nauth Aug 2025

Chromatographic Developments For The Analysis Of Toxic Organic Chemicals In The Environment And Food Samples, Stephanie Devi Nauth

Graduate Thesis and Dissertation post-2024

As awareness grows about compounds harmful to human health, the need for sensitive detection methods at low concentration levels becomes increasingly critical. Chromatography is a powerful analytical technique that enables the separation of complex mixtures, allowing for the simultaneous analysis of multiple analytes—even at trace levels. This dissertation applies chromatography in two distinct contexts: (1) Investigating the sorption of polycyclic aromatic sulfur heterocycles (PASHs) onto nylon microplastics; and (2) Detecting illegal dyes in various food matrices.

Microplastics have emerged as significant vectors for transporting pollutants into aquatic ecosystems. Due to their hydrophobic nature, many organic pollutants readily sorb onto microplastics …


Advancing Ground-Based Instrumentation With Astrophotonics For Stellar Astrophysics And Time-Domain Spectroscopy, Christina D. Moraitis Aug 2025

Advancing Ground-Based Instrumentation With Astrophotonics For Stellar Astrophysics And Time-Domain Spectroscopy, Christina D. Moraitis

Graduate Thesis and Dissertation post-2024

This dissertation presents advancements in Astrophotonics with a focus on PolyOculus technology - a novel, scalable approach to astronomical instrumentation designed to enhance observational capabilities in a cost-effective manner. It details the development of the Original PolyOculus Array (OPA), its integrated light-combining device (the photonic lantern), and its dedicated spectrograph, OPASpec. In parallel, the final commissioning of the MIRADAS Near-Infrared spectrograph is described. These instrumental innovations are applied to key astrophysical investigations, including the search for coronal mass ejections on M-dwarfs and time-resolved spectroscopic monitoring of T Coronae Borealis during its pre-eruption phase. By combining cutting-edge instrument design with cross-institutional …


Preparing For The Habitable Worlds Observatory: Spectropolarimetric Radiative Transfer Models Of Terrestrial (Exo)Planets, Kenneth E. Goodis Gordon Aug 2025

Preparing For The Habitable Worlds Observatory: Spectropolarimetric Radiative Transfer Models Of Terrestrial (Exo)Planets, Kenneth E. Goodis Gordon

Graduate Thesis and Dissertation post-2024

The next major step for the exoplanet community lies in the characterization of terrestrial exoplanets, especially when it comes to identifying biosignatures and determining the habitability of these worlds. In response to this, NASA has proposed the Habitable Worlds Observatory (HWO), with the primary goal of searching for and characterizing Earth-sized planets in the habitable zones (HZ) of their stars. However, current characterization strategies that only rely on the unpolarized flux from the planets lose some of the informational content of the observed light and therefore suffer from degeneracies in the calculated planetary parameters. The sensitivity of polarization to the …


Analysis Of Numerical Methods For Spdes, And Applications Of Free Boundary Problems In Financial Mathematics, Corey A. Prachniak Aug 2025

Analysis Of Numerical Methods For Spdes, And Applications Of Free Boundary Problems In Financial Mathematics, Corey A. Prachniak

Graduate Thesis and Dissertation post-2024

This dissertation studies the key properties of a fully discrete finite element method for a class of stochastic moving boundary problems. Then, free boundary problems and their applications in finance are explored.

The first part of this thesis studies the properties of a proposed fully discrete finite element method scheme with an interpolation operator for stochastic Cahn-Hilliard equations with functional-type noise. These solutions cannot be differentiated in time, so we provide Holder continuity results to aid in the scheme’s error analysis. We further derive the uniform boundedness of higher-order L2-norm moment for use in the analysis. Then nearly …


"Identity (Change) Is Not A Joke, Jim!": The Role Of Change In Responsible Drinking Identity On Behavioral Change In College Alcohol Interventions, Angelina V. Leary Aug 2025

"Identity (Change) Is Not A Joke, Jim!": The Role Of Change In Responsible Drinking Identity On Behavioral Change In College Alcohol Interventions, Angelina V. Leary

Graduate Thesis and Dissertation post-2024

Identity has long fascinated humans, and recent research has explored its role in behavioral change. Identity change may explain why some behavioral interventions are more effective than others. This dissertation examined this idea within the context of college student alcohol interventions. While numerous interventions exist for college students, only some appear to yield long-term effects. It was hypothesized that the key differentiator in effectiveness is how an intervention reshapes an individual’s responsible drinking identity. Participants (71.93% White, 59.40% Female) from a Southeastern university were randomly assigned to one of four intervention conditions: Deviance Regulation Theory (DRT), Personalized Normative Feedback (BASICS), …


It's In My Nature: A Look At The Individual Differences That Influence Perceptions Of Work Stress Recovery With Nature Breaks, Nathaly Rayo Aug 2025

It's In My Nature: A Look At The Individual Differences That Influence Perceptions Of Work Stress Recovery With Nature Breaks, Nathaly Rayo

Graduate Thesis and Dissertation post-2024

The purpose of this study was to explore how individual differences influence employee

perceptions of nature breaks at work. While nature provides restorative benefits to employees such

as reduced fatigue and feelings of recovery and awe, individual differences may impact the fit

between an employee and nature as a desirable work break location. We adopted a person-centered

approach and conducted a Latent Profile Analysis (LPA) using the indicators of nature

connectedness, regulatory focus, uncertainty intolerance, and openness to experience. Results

supported the emergence of four distinct profiles: break under-regulating nature adventurers,

nature-adverse break-takers, nature-loving break self-regulators, and reserved nature-neutral

break-takers. …


Pride Or Prejudice: An Examination Of Queer Content In Florida High Schools, Niamh L. Harrop Aug 2025

Pride Or Prejudice: An Examination Of Queer Content In Florida High Schools, Niamh L. Harrop

Graduate Thesis and Dissertation post-2024

This thesis explores how queer individuals reflect on the presence—or more often, the absence—of queer content in their high school education. Despite increasing visibility of LGBTQ+ people in popular culture and legal reform, formal educational spaces remain largely heteronormative and cisnormative structured from a heterosexual and cisgender standpoint. Through a critical qualitative approach, this study draws on semi-structured interviews with 13 queer participants who attended high school in Florida in the years between the legalization of same-sex marriage in 2015 and the passage of Florida’s H.B. 1557 (“Don’t Say Gay” law) in 2022. Using thematic analysis, four key themes were …


Examining Educational Inequalities And Driving Science’S Next Generation Forward: Geobus Program Theory Evaluation, Elise M. Lorenzo Aug 2025

Examining Educational Inequalities And Driving Science’S Next Generation Forward: Geobus Program Theory Evaluation, Elise M. Lorenzo

Graduate Thesis and Dissertation post-2024

This study presents a theory-driven evaluation of GeoBus, a mobile science lab designed to deliver hands-on, “fun learning experiences” via a solar powered, technology-rich learning environment brought directly to K-12 students in Central Florida Title 1 schools. While STEM education is widely recognized as essential for promoting equity, many schools, particularly in under-resourced communities, continue to face barriers to accessing meaningful and inclusive science learning opportunities. GeoBus was created in response to this need, offering students an informal learning environment with exposure to geospatial technologies and interactive science content.

Drawing on mixed-methods data, including content from the GeoBus website and …


Experiencing Race, Racism And Racialization In Transnational Contexts: Racial Literacies Of First-Year International Asian Students., Nasiba Norova Aug 2025

Experiencing Race, Racism And Racialization In Transnational Contexts: Racial Literacies Of First-Year International Asian Students., Nasiba Norova

Graduate Doctoral Dissertations

This research focused on exploring the racial literacies of first-year international East Asian (EA) students, specifically examining their perceptions of and experiences with race, racism, and racialized groups in various social and educational contexts in both their home countries and the United States. The study used critical ethnography to examine the perspectives of EA international students and composition faculty. It involved multiple semi-structured interviews, journal entries, racial literacy autobiographies, site document analysis, and class observations to understand how students perceived exposure to race, racism, and racialized groups and how faculty viewed the importance of racial education for international students in …


Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez Aug 2025

Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez

Publications and Research

The Southwestern US and northern Mexico continue to serve as ideal regions to elucidate the suite of ecological and evolutionary processes influencing lineage diversification. The complex geological history of arid North America, coupled with paleoclimate change during the Pleistocene and diverse ecoregions makes a multipronged approach to hypothesis testing necessary. We combine thousands of loci from a genotyping-by-sequencing (GBS) approach along with mitochondrial DNA (mtDNA) sequences from the Greater Earless Lizard (Cophosaurus texanus) to examine diversity and test for cryptic population structure. We also apply recently developed coalescent approaches in a Bayesian framework to estimate migration rates. Population …


Hot Spring Associated Infectious Diseases In The Great Basin And Southwest, Matthew Bentz Aug 2025

Hot Spring Associated Infectious Diseases In The Great Basin And Southwest, Matthew Bentz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Like all bodies of freshwater, natural hot springs can harbor pathogenic microorganisms that carry the threat of infectious disease. The unique chemistry, increased temperature, and popularity for bathing may alter the risk profile of hot springs compared to other natural bodies of water. Despite this risk, the role of hot springs as a reservoir for infectious diseases remains understudied, particularly within the context of regional public health. Nevada and the Great Basin/Southwest have increasingly promoted hot springs for the purposes of tourism, and they share a strong link to the cultural heritage of the region. The unknown risk profile and …


Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto Aug 2025

Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto

UNLV Theses, Dissertations, Professional Papers, and Capstones

Understanding the functional consequences of genetic mutations remains a central challenge in modern biology, with far-reaching implications for human health and disease. While early systematic methods like alanine scanning and phage display provided foundational insights into protein structure and function, the emergence of high-throughput approaches—such as Multiplexed Assays of Variant Effect (MAVEs)—and predictive tools powered by artificial intelligence have vastly expanded our ability to profile mutational landscapes. However, these methods are often constrained by trade-offs between accuracy, scalability, and biological relevance.This dissertation presents the development and application of the GigaAssay, the world’s first high-throughput functional assay capable of delivering both …