Digital Commons Network^™

A Novel Neutrograph Model For Dynamic Systems: Advancing Neutrostructures With Partially False Axioms In Interactive Digital Installation Art Design, Ziyuan Liu, Yixi Peng

Neutrosophic Sets and Systems

No abstract provided.

A Neutrosophic Reversibility Tensor Model For Analyzing Quality Dynamics In Academic Discipline Construction At Local Application-Oriented Universities Based On Artificial Intelligence Technology, Chang Liu

Neutrosophic Sets and Systems

No abstract provided.

Advancing Breast Cancer Diagnosis: A Comprehensive Machine Learning Approach For Predicting Malignant And Benign Cases With Precision And Insight In A Neutrosophic Environment Using Neutrosophic Numbers, Nihar Ranjan Panda, R. Rajalakshmi, Surapati Pramanik, Mana Donganont, Prasanta Kumar Raut

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic-Based Cephalometric Analysis For Egyptian Population Using Novel Software, Nagham Ahmed Abdelmegeed, Amal F.Abdel-Gawad, Mohamed Alaa Fahmy El-Ghamry

Neutrosophic Sets and Systems

No abstract provided.

Multi-Valued Multi-Polar Neutrosophic Sets For Ideological And Political Education Quality In The New Media Environment, Xuchen Du

Neutrosophic Sets and Systems

No abstract provided.

Phl 523.01: Science And The Environment, Armond J. Duwell

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 588.01: School Psychology Internship, Anisa N. Goforth

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Nrsm 579.01: Practicum In Collaborative Conservation, Shawn M. Johnson, Nicolas T. Maya

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Consumption Of Negative Media Content Mediates The Association Between Levels Of Trauma Exposure And Insomnia Severity In Hispanic Young Adults, Michiyo Hirai, Laura L. Vernon

Psychological Science Faculty Publications

Research has shown that individuals who have experienced traumatic events are at greater risk of developing severe insomnia than those without trauma. Further, according to the stress sensitization hypothesis, victims of multiple traumas, compared to those who have experienced a single trauma, are particularly vulnerable to severe insomnia. One potential mechanism underlying the association between trauma experiences and insomnia is media exposure. Although avoidance behaviors are symptoms of posttraumatic stress, victims of traumas also demonstrate attentional bias toward threats and difficulty disengaging attention from threats. These cognitive tendencies may result in heightened vigilance to negative media content, particularly trauma-related content, …

Botulinum Neurotoxin Light Chain/A1 Uses Fast Synaptic Vesicle Cycling To Cleave Plasma Membrane Bound Snap-25, Alexander Gardner, Molly Sneller, William H. Tepp, Joseph T. Barbieri, Sabine Pellett

College of Nursing Faculty Research and Publications

Botulinum neurotoxins (BoNT) are the most potent protein toxins for humans, yet how BoNT-Light Chain/A1 (LC/A1) journeys to cleave intracellular SNAP-25 is understudied. Here we use a cell-based assay to measure cytosolic EGFP-LC/A1 intracellular trafficking and SNAP-25 cleavage in Neuro-2A cells. Intracellular LC/A1 associated on microtubules and co-localized with Rab GTPases involved in fast synaptic vesicles and endosome recycling. Multiple Dominant Negative (DN) Rabs GTPases involved in fast synaptic vesicles or endosome recycling inhibited LC/A1 trafficking to the intracellular plasma membrane and SNAP-25 cleavage. A cytosolic LC/A1 variant that bound the plasma membrane from the cytosol was insensitive to DNRab …

Synthetic Zfta Fusions Pinpoint Disordered Protein Domain Acquisition As A Mechanism Of Brain Tumorigenesis, A Arabzade, H K Shirnekhi, S Varadharajan, S M Ippagunta, A H Phillips, N Laboe, D W Baggett, Wahiduzzaman, M Jo, T Zheng, R Pathak, D Gee, D Bhimsaria, H Wu, X Gao, J Liu, E Emanus, A Bland, A Kardian, A Hancock, B Holcomb, T Wright, T Bugbee, H Sun, M Zhai, E Caesar, M Park, S Tripathi, A Shirinifard, K Lowe, A Khalighifar, R A Petersen, S King, D Stabley, A Pitre, G E Campbell, C-G Park, W T Freyaldenhoven, B Chandra, Y Xia, E Bonten, A Achari, S Kandikonda, A Carisey, S B Pounds, J Xu, D W Ellison, B Deneen, K C Bertrand, R W Kriwacki, S C Mack

Children’s Nutrition Research Center Staff Publications

Over 95% of ependymomas that arise in the cortex are driven by a gene fusion involving the zinc finger translocation-associated (ZFTA) protein. Here, using super-resolution and lattice light-sheet microscopy, we demonstrate that the most frequent fusion variant, ZFTA-RELA (ZR), forms dynamic nuclear condensates that are required for oncogene expression and tumorigenesis. Mutagenesis studies of ZR reveal a key intrinsically disordered region (IDR) in RELA that governs condensate formation. Condensate-modulating IDR mutations introduced into ZR impaired its genomic occupancy at oncogenic loci and inhibited the recruitment of transcriptional effector proteins, such as MED1, BRD4 and RNA polymerase II. Using nuclear magnetic …

A Consensus Guide To Preclinical Indirect Calorimetry Experiments, Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Johan Auwerx, Julio E Ayala, Joseph A Baur, Stefania Carobbio, Gary A Churchill, Morten Dall, Rafael De Cabo, Jose Donato, Nathalia R V Dragano, Carol F Elias, Anthony W Ferrante, Brian N Finck, Jose E Galgani, Zachary Gerhart-Hines, Laurie J Goodyear, Justin L Grobe, Rana K Gupta, Kirk M Habegger, Sean M Hartig, Andrea L Hevener, Steven B Heymsfield, Corey D Holman, Martin Hrabě De Angelis, David E James, Lawrence Kazak, Jae Bum Kim, Martin Klingenspor, Xingxing Kong, Sander Kooijman, Louise Lantier, K C Kent Lloyd, James C Lo, Irfan J Lodhi, Paul S Maclean, Owen P Mcguinness, Gema Medina-Gómez, Raghavendra G Mirmira, Christopher D Morrison, Gregory J Morton, Timo D Müller, Yoshihiro Ogawa, David Pajuelo-Reguera, Matthew J Potthoff, Nathan Qi, Marc L Reitman, Patrick C N Rensen, Jan Rozman, Jennifer M Rutkowsky, Kei Sakamoto, Philipp E Scherer, Gary J Schwartz, Radislav Sedlacek, Mohammed Selloum, Saame Raza Shaikh, Shuai Chen, Gerald I Shulman, Vojtěch Škop, Alexander A Soukas, John R Speakman, Bruce M Spiegelman, Gregory R Steinberg, Katrin J Svensson, John P Thyfault, Tony Tiganis, Paul M Titchenell, Nigel Turner, Licio A Velloso, Antonio Vidal-Puig, Christopher S Ward, Ashley S Williams, Christian Wolfrum, Allison W Xu, Ying Xu, Juleen R Zierath, International Indirect Calorimetry Consensus Committee (Iiccc)

Children’s Nutrition Research Center Staff Publications

Understanding the complex factors influencing mammalian metabolism and body weight homeostasis is a long-standing challenge requiring knowledge of energy intake, absorption and expenditure. Using measurements of respiratory gas exchange, indirect calorimetry can provide non-invasive estimates of whole-body energy expenditure. However, inconsistent measurement units and flawed data normalization methods have slowed progress in this field. This guide aims to establish consensus standards to unify indirect calorimetry experiments and their analysis for more consistent, meaningful and reproducible results. By establishing community-driven standards, we hope to facilitate data comparison across research datasets. This advance will allow the creation of an in-depth, machine-readable data …

Randomized Trial: Peppermint Oil (Menthol) Pharmacokinetics In Children And Effects On Gut Motility In Children With Functional Abdominal Pain: 540 Mg Vs. 900 Mg Dose Comparison, Robert J Shulman, Bruno P Chumpitazi, Daniel Gonzalez, Uttam Garg, Salma Musaad, Jiali Wen, Gregory L Kearns

Children’s Nutrition Research Center Staff Publications

Aims: There is a paucity of information on the pharmacokinetics (PK) and pharmacodynamics (PD) of menthol, the active ingredient in peppermint oil (PMO). We studied the PK of menthol (540 and 900 mg) in children and measured their effects on gut transit/contractility.

Methods: Children 7-12 years of age with functional abdominal pain underwent wireless motility capsule (WMC) testing. One week later, they were randomized to 540 mg or 900 mg of oral enteric-coated PMO. Blood was sampled over 24 h to determine menthol PK. The WMC test was repeated while they took their respective dose (180 mg thrice or 180 …

Beyond Brushing: Can Toothpaste Cure Your Child’S Peanut Allergy?, Michael J. Heiss D.D.S., Benjamin Solomowitz Dmd

The New York State Dental Journal

Peanut allergies pose significant health risks globally, with an increasing prevalence observed over the past two decades. Accidental exposures to peanuts can lead to severe allergic reactions, including anaphylaxis, prompting the exploration of innovative therapeutic approaches to mitigate these risks. This literature review examines the potential use of peanut proteins embedded within toothpaste formulations as a novel avenue for inducing tolerance in individuals with peanut allergies. It includes recent studies and clinical trials in oral immunotherapy, focusing on mechanisms of action, safety profiles and long-term outcomes associated with controlled allergen exposure. Key findings suggest that oral mucosal therapy, particularly sublingual …

Gorlin-Goltz Syndrome With Familial Manifestation: A Case Report With Emphasis On Early Diagnosis, Ravinder Singh, Deepak Gupta, Aashna Garg, Aanchal Gupta, Sushruh Nayak

The New York State Dental Journal

Gorlin-Goltz syndrome is a hereditary autosomal dominant disorder. It has multiple clinical manifestations caused by mutation in the patched gene (PTCH), which is responsible for the growth and development of healthy tissue and for regulating the cell cycle. Early diagnosis of the condition and an extended duration of follow-up are essential to prevent complications, such as basal cell carcinomas and facial deformities, leading to a more favorable prognosis. This case was diagnosed with the presence of three major and two minor criteria, which confirmed the condition. We hereby report a case of a young male patient diagnosed by clinical, radiological …

Exploring The Contextual Antecedents Of Nonfamilial Aggression In Women Arrested For Aggressive Behavior, Tatiana Pouncy

Walden Dissertations and Doctoral Studies

The prevalence of physical aggression among women has increased, challenging traditional gender norms that portray women as nurturing and nonviolent. While most research on aggression has focused on men, children, or intimate partner violence, research is sparse concerning female aggression outside familial contexts. In this qualitative multiple-case study, the contextual antecedents of nonfamilial aggression in women arrested for aggressive behavior were explored using the general aggression model as the theoretical framework. Data were obtained from 20 publicly documented cases using archival sources such as media stories, court documents, and video recordings. According to thematic and document analysis, aggressive behavior was …

Anty 515.01: Theories And Methods In Bioanthropology, Elizabeth A. Bews

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ad-150: Color And Composition, Section 009, Thomas Carlson

School of Art and Design Syllabi

No abstract provided.

Ad-150: Color And Composition, Section 001, Martin Short

School of Art and Design Syllabi

No abstract provided.

Ad-150: Color And Composition, Section 011, Glenn Goldman

School of Art and Design Syllabi

No abstract provided.

Ad-150: Color And Composition, Section 005, Sophia Sobers

School of Art and Design Syllabi

No abstract provided.

Hss 404-H01: Health, Justice, & Capitalism, Stephen Pemberton

History Syllabi

No abstract provided.

A Metabolomics Study Of Cardiac Dysfunction In Hyperglycemia: Findings From The Atherosclerosis Risk In Communities (Aric) Study And The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Yilin Yoshida, Ngoc Quynh Nguyen, Eun Hye Moon, Casey Rebholz, Hicham Skali, Victoria Arthur, Justin B Echouffo-Tcheugui, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J Rodriguez, Qibin Qi, Susan Cheng, Bing Yu

Faculty, Staff and Student Publications

Objective: Hyperglycemic states (prediabetes and diabetes) are associated with heart failure (HF) risk. We aimed to identify distinct metabolites for subclinical cardiac dysfunction, a precursor of HF, in hyperglycemic or euglycemic individuals.

Research design and methods: We conducted cross-sectional and prospective analyses of 2,492 HF-free participants from the Atherosclerosis Risk in Communities (ARIC) study visit 5, 2011-2013. A total of 1,297 participants were hyperglycemic (assessed on the basis of hemoglobin A1c >5.7%, fasting glucose >100 mg/dL, use of diabetes medication, or diagnosis), and 1,195 were euglycemic. We used logistic regression for analysis of association between 790 metabolites and cardiac dysfunction, …

Anty 101h.50: Anthropology And The Human Experience, Erin D. Rosenkrance

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Bioh 291.01: Human Gross Anatomy – Cadaver Dissection, Lucas Whitcher

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Wild 346.00: Wildlife Physiological Ecology, Creagh W. Breuner

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Anty 122s.01: Race And Minorities, Gregory R. Campbell

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Anty 213n.00: Biological Anthropology Lab, Elizabeth A. Bews, Courtney C. Manthey

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Comx 380.01: Gender And Communication, Sara E. Hayden

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Phl 101l.01: Introduction To Philosophy, Jeffrey E. Stephenson

University of Montana Course Syllabi, 2021-2025

No abstract provided.