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Articles 24301 - 24330 of 818067
Full-Text Articles in Entire DC Network
Effect Of Vitamin D Supplementation During Pregnancy And Lactation On The Development Of Infants Born To Tanzanian Women Living With Hiv: A Secondary Analysis Of A Randomised Controlled Trial, Temiwunmi Shobanke, Alfa Muhihi, Nandita Perumal Phd, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Christopher P. Duggan, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld
Effect Of Vitamin D Supplementation During Pregnancy And Lactation On The Development Of Infants Born To Tanzanian Women Living With Hiv: A Secondary Analysis Of A Randomised Controlled Trial, Temiwunmi Shobanke, Alfa Muhihi, Nandita Perumal Phd, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Christopher P. Duggan, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld
Faculty Publications
Background Infants born to pregnant women living with HIV (WLHIV) are at greater risk for morbidity and mortality and may also have poorer developmental outcomes as compared with infants who are not exposed to HIV. Nutrition interventions in pregnancy may affect developmental outcomes.
Objectives This study evaluated the effect of maternal vitamin D supplementation on infant development outcomes.
Design We conducted a secondary analysis of a randomised, triple-blind, placebo-controlled trial of maternal vitamin D supplementation from June 2015 to October 2019.
Setting Antenatal care clinics in Dar es Salaam, Tanzania.
Participants Pregnant WLHIV and their offspring.
Interventions Daily 3000 IU …
The Chromosome Complement Of Male Chrysoperla Rufilabris (Burmeister, 1839), With Evidence Of Distance Segregation In Meiosis I, Valoria G. Maslin, Allison M. Eisenhauer, Leocadia V. Paliulis
The Chromosome Complement Of Male Chrysoperla Rufilabris (Burmeister, 1839), With Evidence Of Distance Segregation In Meiosis I, Valoria G. Maslin, Allison M. Eisenhauer, Leocadia V. Paliulis
Faculty Journal Articles
Neuropteran insects display a phenomenon called distance segregation during male meiosis I, where the X and Y chromosomes are unconnected from prometaphase I through anaphase I. Here we investigate chromosome number and patterns of chromosome segregation of a previously unstudied Neuropteran: the green lacewing, Chrysoperla rufilabris (Burmeister, 1839). Testes of male C. rufilabris were isolated and prepared following a chromosome squash method. Living meiosis I spermatocytes were also imaged. The data revealed a chromosome number of 2n=12 in males (2n=10+XY) and evidence of distance segregation of X and Y chromosomes in meiosis I spermatocytes.
Salvage Therapies For First Relapse Of Shh Medulloblastoma In Early Childhood., Craig Erker, Martin Mynarek, Marie Simbozel, Brandon T. Craig, Virginia L. Harrod, Andrea M. Cappellano, Kenneth J. Cohen, Vicente Santa-Maria Lopez, Andres Morales La Madrid, Chantel Cacciotti, Lorena Baroni, Ralph Salloum, Ashley S. Margol, George Michaiel, Dolly Aguilera, Claire M. Mazewski, Cassie N. Kline, Jonathan L. Finlay, Mohamed S. Abdelbaki, Jeffrey C. Murray, Kathleen Dorris, Bruce Crooks, Kevin Ginn, Nisreen Amayiri, Stephan Tippelt, Gudrun Fleischhack, Svenja Tonn, Nicolas U. Gerber, Alvaro Lassaletta, Jordan R. Hansford, Sara Khan, Stephen W. Gilheeney, Lindsey M. Hoffman, Michal Zapotocky, Valérie Larouche, Shafqat Shah, Vijay Ramaswamy, Amar Gajjar, Sébastien Perreault, Sabine Mueller, Juliette Hukin, Sylvia Cheng, Zhihong J. Wang, Kara Matheson, Simon Bailey, Eric Bouffet, Steven C. Clifford, Giles Robinson, Christelle Dufour, Stefan Rutkowski, Lucie Lafay-Cousin
Salvage Therapies For First Relapse Of Shh Medulloblastoma In Early Childhood., Craig Erker, Martin Mynarek, Marie Simbozel, Brandon T. Craig, Virginia L. Harrod, Andrea M. Cappellano, Kenneth J. Cohen, Vicente Santa-Maria Lopez, Andres Morales La Madrid, Chantel Cacciotti, Lorena Baroni, Ralph Salloum, Ashley S. Margol, George Michaiel, Dolly Aguilera, Claire M. Mazewski, Cassie N. Kline, Jonathan L. Finlay, Mohamed S. Abdelbaki, Jeffrey C. Murray, Kathleen Dorris, Bruce Crooks, Kevin Ginn, Nisreen Amayiri, Stephan Tippelt, Gudrun Fleischhack, Svenja Tonn, Nicolas U. Gerber, Alvaro Lassaletta, Jordan R. Hansford, Sara Khan, Stephen W. Gilheeney, Lindsey M. Hoffman, Michal Zapotocky, Valérie Larouche, Shafqat Shah, Vijay Ramaswamy, Amar Gajjar, Sébastien Perreault, Sabine Mueller, Juliette Hukin, Sylvia Cheng, Zhihong J. Wang, Kara Matheson, Simon Bailey, Eric Bouffet, Steven C. Clifford, Giles Robinson, Christelle Dufour, Stefan Rutkowski, Lucie Lafay-Cousin
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Sonic hedgehog (SHH) medulloblastoma is the most common molecular group of infant and early childhood medulloblastoma (iMB) and has no standard of care at relapse. This work aimed to evaluate the post-relapse survival (PRS) and explore prognostic factors of patients with nodular desmoplastic (ND) and/or SHH iMB.
METHODS: This international retrospective study included 147 subjects diagnosed with relapsed ND/SHH iMB between 1995 and 2017, < 6 years old at original diagnosis, and treated without initial craniospinal irradiation (CSI). Univariable and multivariable Cox models with propensity score analyses were used to assess PRS for those in the curative intent cohort.
RESULTS: The 3-year PRS was 61.6% (95% confidence interval [CI], 52.2-69.6). The median age at relapse was 3.4 years (interquartile range [IQR], 2.6-4.1). Those with local relapse (40.8%) more often received salvage treatment with surgery …
On Good Terms: Pathways To Decolonizing Science-Appropriated Indigenous Terminologies In Arctic Research, Stanislav Saas Ksenofontov, Vera Kuklina, Alexander Kholodov, Andrey Petrov
On Good Terms: Pathways To Decolonizing Science-Appropriated Indigenous Terminologies In Arctic Research, Stanislav Saas Ksenofontov, Vera Kuklina, Alexander Kholodov, Andrey Petrov
Faculty Publications
Many western scientific disciplines adopted Indigenous Knowledge and terminology without deference to or understanding of the original meanings and values attached to Indigenous terms and concepts. This form of scientific appropriation has become a serious barrier to efforts of decolonizing Arctic research. The notion of Alaas is an example of such appropriation by the western science-based system of Indigenous knowledge about human–nature relations. This paper aims to discuss the term Alaas as it is conceptualized in both western science and Indigenous knowledge. The paper will explore the development of “alas” as an international permafrost science term and Alaas as an …
Bard1: A Friend Or Foe In Pancreatic Ductal Adenocarcinoma?, Lily Zekavat, Aditi Jain
Bard1: A Friend Or Foe In Pancreatic Ductal Adenocarcinoma?, Lily Zekavat, Aditi Jain
Department of Surgery Faculty Papers
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive solid malignancy with poor overall prognosis and limited response to standard treatments. Growing interest in the modulation of DNA repair mechanisms, including the homologous recombination (HR) repair pathway, has opened new avenues for therapeutic development. BARD1 (BRCA1-Associated RING Domain 1) plays a complex role in tumor biology, functioning either as a tumor suppressor or as an oncogenic driver, depending on isoform expression, cellular context, and regulatory environment. In this review, we examine the dual roles of BARD1, focusing on its regulation and paradoxical activities in PDAC. We summarize evidence that BARD1 and BARD1 …
Effect Of Gingival Pigmentations And Anterior Crown Heights On Smile Attractiveness Regarding Gingival Exposure Assed By Orthodontists, Dentists, And Laypeople: A Randomized Controlled Trial, Ziad Tannoury, Marianne Moussallem, Joseph Ghoubril, Adib Kassis, Elie Khoury
Effect Of Gingival Pigmentations And Anterior Crown Heights On Smile Attractiveness Regarding Gingival Exposure Assed By Orthodontists, Dentists, And Laypeople: A Randomized Controlled Trial, Ziad Tannoury, Marianne Moussallem, Joseph Ghoubril, Adib Kassis, Elie Khoury
International Arab Journal of Dentistry
Objectives: The purpose of this study was to evaluate the effect of gingival pigmentations and anterior crown heights in conjunction with the maxillary gingival display on the perception of smile attractiveness assessed by orthodontists, dentists, and laypersons.
Methods: Frontal intraoral photograph of ideally aligned teeth was modified to generate 3 levels of gingival smile exposure (2 mm, 3 mm, and 4 mm) with 4 different degrees of gingival pigmentation index according to DOPI and 5 different central incisors crown heights (7.7 mm, 8.7 mm, 9.7 mm, 10.7 mm, and 11.7 mm). Attractiveness of these 24 smiles was evaluated by orthodontists …
Concomitant Anterior Cruciate Ligament And Medial Collateral Ligament Reconstruction: A Systematic Review, Daniel C Touhey, Francisco N Garcia, Sina Tartibi, Robert H Brophy, Matthew J Matava, Matthew V Smith, Derrick M Knapik
Concomitant Anterior Cruciate Ligament And Medial Collateral Ligament Reconstruction: A Systematic Review, Daniel C Touhey, Francisco N Garcia, Sina Tartibi, Robert H Brophy, Matthew J Matava, Matthew V Smith, Derrick M Knapik
2020-Current year OA Pubs
BACKGROUND: Concomitant anterior cruciate ligament (ACL) and medial collateral ligament (MCL) injuries are among the most commonly reported injury patterns in high-energy knee injuries. Concomitant ACL and MCL reconstruction (ACLR + MCLR) is indicated in patients with full-thickness tears and persistent valgus laxity.
PURPOSE: To systematically review the literature to identify studies reporting on patients undergoing concurrent primary ACLR + MCLR to better understand current indications, surgical techniques, complications, and outcomes.
STUDY DESIGN: Systematic review; Level of evidence, 4.
METHODS: Under the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, 702 studies published in PubMed, EMBASE, and the …
Inside Awamc, September 2009, Advocate Health - Midwest
Inside Awamc, September 2009, Advocate Health - Midwest
Historical Documents - Combined
Aurora West Allis Medical Center, West Allis, WI: Inside AWAMC is a monthly newsletter for employees, volunteers, and guests of the hospital. This issue announces the hospital was recognized by Press Ganey Associates for patient loyalty.
Inside Wamh, July 2006, Advocate Health - Midwest
Inside Wamh, July 2006, Advocate Health - Midwest
Historical Documents - Combined
West Allis Memorial Hospital, West Allis, WI: Inside WAMH is a monthly newsletter for employees, volunteers, and guests of the hospital. This issue includes a list of events the hospital sponsored for the West Allis Centennial.
Hubungan Kesadaran Metakognisi Dan Literasi Digital Dengan Hasil Belajar Ipa Siswa Smp Kelas Viii, Kansa Nur Annisa, Riezky Maya Probosari, Sri Yamtinah
Hubungan Kesadaran Metakognisi Dan Literasi Digital Dengan Hasil Belajar Ipa Siswa Smp Kelas Viii, Kansa Nur Annisa, Riezky Maya Probosari, Sri Yamtinah
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
The research aims to analyze relationship between metacognitive awareness and digital literacy with science learning outcomes. This research is a correlational study with a quantitative approach. The research sample used the entire population, amounting to 232 class VIII students. Data was collected using a metacognitive awareness and digital literacy questionnaire, also documentation of science learning outcomes. The results of the questionnaire data were changed with Measurement Sucsessive Interval. The results showed that there was a significant relationship between metacognitive awareness and science learning outcomes, digital literacy with science learning outcomes, and metacognitive awareness and digital literacy with science learning outcomes. …
Efektivitas Media Interaktif Berbasis Nearpod Terhadap Hasil Belajar Siswa Pada Materi Sistem Ekskresi, Rofiana Kusuma Pinawadhani, Kurnia Ningsih, Ruqiah Ganda Putri Panjaitan
Efektivitas Media Interaktif Berbasis Nearpod Terhadap Hasil Belajar Siswa Pada Materi Sistem Ekskresi, Rofiana Kusuma Pinawadhani, Kurnia Ningsih, Ruqiah Ganda Putri Panjaitan
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to determine the effectiveness of nearpod-based interactive media on student learning outcomes on excretory system material for class XI SMAN 8 Pontianak. This study used a Quasi-Experimental method with a Pre-test Post-test Control Group Design. The average post-test for the experimental class is 79.29, which is higher than the control class, which is 72.06. Data on learning outcomes were analyzed using the Independent Sample t-test and obtained 0.001 <0.05 so that there is differences in learning outcomes between the experimental and control classes. The effect size value is 0.76 in the high category and contributes 27.64% to learning, so it can be concluded that nearpod-based interactive media affects learning outcomes.
Retracted: The Relationship Between Explanatory Ability And Collegiate Learning Assessment Task, Monika Lintang Laksmi, Baskoro Adi Prayitno, Meti Indrowati
Retracted: The Relationship Between Explanatory Ability And Collegiate Learning Assessment Task, Monika Lintang Laksmi, Baskoro Adi Prayitno, Meti Indrowati
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
RETRACTED: The editorial board of JPtpp has officially retracted the article "The Relationship between Explanatory Ability and Collegiate Learning Assessment Task" (Vol. 9, No.9, pp.398-409, September, 2024), due to a violation of publication ethics.
Following a thorough review, the editor confirmed that this paper represents a duplicate publication. It contains redundant material previously published in JPtpp Vol. 8, No.2, pp.100-107, February 2023, URL: https://citeus.um.ac.id/jptpp/vol8/iss2/5/, under the title "The Relationship between Explanatory Ability and Collegiate Learning Assessment Task".
In accordance with institutional policies, the digital version of this document has been removed from previously published, and all citations or references …
Penerapan Model Problem Based Learning Pada Materi Pembelajaran Ipa Siswa Kelas V Kurikulum 2013, Muhammad Feri, Mohamad Agung Rokhimawan
Penerapan Model Problem Based Learning Pada Materi Pembelajaran Ipa Siswa Kelas V Kurikulum 2013, Muhammad Feri, Mohamad Agung Rokhimawan
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study means to decide the impact of the Problem Based Learning (PBL) model on the learning results of Science class V understudies in the 2013 educational program. The methodology utilized in this study is a quantitative methodology utilizing numbers and factual examination of information. This exploration configuration utilizes Quasi-Experimental Design, which is a control group that isn't completely practical to control outside factors. The type of exploration is Nonequivalent Control Group Design which is practically equivalent to Pretest-posttest Control Group Design however here, the exploratory gathering and control bunch are not arbitrarily chosen. The subject of this review is …
The Effect Of Open-Ended Worksheets In Interactive Demonstration Learning On Students’ Conceptual Understanding Of Harmonic Motion And Scientific Reasoning, Abdur Rohman Wahid Arrosyid, Sentot Kusairi, Hari Wisodo
The Effect Of Open-Ended Worksheets In Interactive Demonstration Learning On Students’ Conceptual Understanding Of Harmonic Motion And Scientific Reasoning, Abdur Rohman Wahid Arrosyid, Sentot Kusairi, Hari Wisodo
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This research explores the influence of using open-ended worksheets in interactive demonstration learning on students' understanding of harmonic motion and scientific reasoning. It is a quasi-experimental study with a pretest-posttest control group design. Data were obtained from conceptual understanding and scientific reasoning tests and analyzed using parametric and non-parametric tests. The results show that open-ended worksheets enhance students' concept comprehension and scientific reasoning. There was a significant difference in conceptual understanding between the two classes. However, there was no difference in scientific reasoning. These findings hold valuable implications for improving learning with open-ended worksheets and interactive demonstration models.
The Influence Of Learning Models (Pjbl & Pbl) And Learning Styles (Visual & Auditory) On Biology Learning Outcomes, I Gede Ratnaya, Rosalina S.S. Son, Agsen H.S. Billik, Adam Smith Bago
The Influence Of Learning Models (Pjbl & Pbl) And Learning Styles (Visual & Auditory) On Biology Learning Outcomes, I Gede Ratnaya, Rosalina S.S. Son, Agsen H.S. Billik, Adam Smith Bago
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to determine: (1) Differences in biology learning outcomes between students taught with PJBL (project based learning) learning model and biology learning outcomes of students taught with PBL (problem based learning) learning model (2) Differences in biology learning outcomes between students who have a visual learning style and who have an auditorial learning style, (3) interaction between learning models and learning styles on biology learning outcomes. The research method used a quasi- experimental method with a research design = faktorial 2 x 2. The data analysis technique used two-way ANOVA at a significant level of 0.05. The results …
Penerapan Strategi Reframing Dengan Pendidikan Karakter Islami Bagi Siswa Kelas Vii Mts Negeri 1 Pontianak, Wahab Wahab, Yulisa Rizki Nurmadinah, Nurul Huda
Penerapan Strategi Reframing Dengan Pendidikan Karakter Islami Bagi Siswa Kelas Vii Mts Negeri 1 Pontianak, Wahab Wahab, Yulisa Rizki Nurmadinah, Nurul Huda
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Changes in the form or pattern of thinking and behavior of most children today are not something that is easy to study. From the observations obtained, there are very few children who display good behavior, especially at the Mts level, especially at MTs Negeri 1 Pontianak. With this, the technique of reframing words or reframing is present in destroying negative behavior and morals in this day and age. The aim of this research is to be able to emphasize the reframing strategy in the implementation or application process, apart from that, the reframing strategy can also be said to be …
Implementation Of Professional Development Programs For Science Teachers And Education Personnel In Stem Learning (Case Study In Indonesia), Lintang Ratri Prastika, Reza Setiawan, Zuhe Safitra, Ayu Intan Harisbaya
Implementation Of Professional Development Programs For Science Teachers And Education Personnel In Stem Learning (Case Study In Indonesia), Lintang Ratri Prastika, Reza Setiawan, Zuhe Safitra, Ayu Intan Harisbaya
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
As a SEAMEO Centre with a mandate to enhance the competence of science teachers and educational personnel in Southeast Asia, SEAMEO QITEP in Science (SEAQIS) consistently develops programs in line with the current trends in education, one of which is STEM Education. Using a descriptive method, this article aims to provide an overview of the STEM program developed by SEAQIS and its implementation in Indonesia from 2016 to 2023. There are 92 SEAQIS programs related to enhancing the competence of science teachers and educational personnel in STEM learning in Indonesia, with a total of 8,388 participants. Overall, from 2016 to …
Biodiversity-Based Learning Citizen Science Project To Stimulus Product Variations In Students' Learning Res, Utari Akhir Gusti, Topik Hidayat, Siti Sriyati, Nur Hamidah
Biodiversity-Based Learning Citizen Science Project To Stimulus Product Variations In Students' Learning Res, Utari Akhir Gusti, Topik Hidayat, Siti Sriyati, Nur Hamidah
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This research aims to explore variations in student learning outcomes in Citizen Science Project (CSP) based biodiversity learning. The research method uses qualitative with a phenomenological approach to detail students' holistic experiences and understand the essence of the products produced. This research design was carried out by combining interviews, observation, and analysis of student products as the main data sources. The research was carried out in one of the schools in Bandung City. The research results showed that students produced a variety of products, including herbariums, posters, posts on the PlantNet application, and inventory books. The overall product reflects a …
Peran Keluarga Dalam Mendidik Anak Menurut Abdurrahman An Nahlawi, Ulli Tiyas Rachmawati, Ummi Khariroh, Basuki Basuki
Peran Keluarga Dalam Mendidik Anak Menurut Abdurrahman An Nahlawi, Ulli Tiyas Rachmawati, Ummi Khariroh, Basuki Basuki
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Family education places the responsibility of parents as the first educators. The family environment is the smallest unit in society because children from birth to adulthood are educated in the family. The purpose research is to examine the influence and role of parents in educating children so that character to build character. The research method is a literature review that uses two sources, namely the primary source of the book Usul at-Tarbiyyah Al-Islamiyyah wa Asalibiha fi al-Bait wa al-Madrasah wa al-Mujtama'. Research procedures with data input, data processing, data analysis and conclusions. The results of the research is upholding the …
Cv: Mallory Havens (Biology), Mallory Havens
Cv: Mallory Havens (Biology), Mallory Havens
Biology Department Faculty Curricula Vitae
No abstract provided.
Allegations Of Human Rights Abuses In Tsumeb, Namibia, Sarah Dávila A.
Allegations Of Human Rights Abuses In Tsumeb, Namibia, Sarah Dávila A.
Faculty White Papers
No abstract provided.
Parameters Autumn 2025, Usawc Press
Parameters Autumn 2025, Usawc Press
The US Army War College Quarterly: Parameters
No abstract provided.
Disinformation As Ground-Shifting In Great-Power Competition, Sorin Adam Matei
Disinformation As Ground-Shifting In Great-Power Competition, Sorin Adam Matei
The US Army War College Quarterly: Parameters
Disinformation, distinct from misinformation, replaces accepted principles of objectivity and verifiability with novelty, framing, authority, self-reference, and conformity to create a new “truth paradigm.” This article introduces a novel definition and framework for understanding disinformation as a strategic tool in great-power competition. It includes a review of case studies, such as Russian disinformation campaigns during the Russia-Ukraine War and analyzes cognitive biases and social behaviors that facilitate the spread of disinformation. Policy and military practitioners will find actionable insights into countering disinformation, including its sociopsychological mechanisms and proposed targeted counterstrategies to protect the integrity of information flows in defense and …
04. Equilibrium Thermodynamics Iv: Applications, Gerhard Müller
04. Equilibrium Thermodynamics Iv: Applications, Gerhard Müller
Equilibrium Statistical Physics
Part four of course materials for Statistical Physics I: PHY525, taught by Gerhard Müller at the University of Rhode Island. Documents will be updated periodically as more entries become presentable.
Updated with version 2 on 1/8/2026.
Artificial Intelligence In Head And Neck Cancer: Towards Precision Medicine., Jacob Hagen, Logan Hornung, William Barham, Supratik Mukhopadhyay, Ada Bess, Kevin Contrera, Kevin Contrera, Devraj Basu, Vlad Sandulache, Guillaume Spielmann, Sagar Kansara
Artificial Intelligence In Head And Neck Cancer: Towards Precision Medicine., Jacob Hagen, Logan Hornung, William Barham, Supratik Mukhopadhyay, Ada Bess, Kevin Contrera, Kevin Contrera, Devraj Basu, Vlad Sandulache, Guillaume Spielmann, Sagar Kansara
School of Medicine Faculty Publications
Simple Summary: This review was conducted to highlight current and potential applications of artificial intelligence (AI) in the care of patients with head and neck cancer, the barriers to its clinical implementation, and the relative scarcity of research in this field. While AI has demonstrated success in other areas of oncology, its role in head and neck cancer remains limited, with progress slowed by technical, ethical, and logistical challenges. Nevertheless, integrating AI with multiomics approaches presents a promising opportunity to advance precision medicine in this patient population. The findings presented in this manuscript may encourage further multi-institutional studies aimed at …
B-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction Inhibiting Peptidomimetics, Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang
B-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction Inhibiting Peptidomimetics, Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang
USF Patents
Disclosed herein is a series of helical sulfono-γ-AApeptides that mimic the binding mode of the α-helical HD2 domain of B-Cell Lymphoma 9 (BCL9). As disclosed herein, sulfono-γ-AApeptides can structurally and functionally mimic the α-helical domain of BCL9, and selectively disrupt β-catenin/BCL9 PPIs with even higher potency. More intriguingly, these sulfono-γ-AApeptides can enter cancer cells, bind with β-catenin and disrupt β-catenin/BCL PPI, and exhibit excellent cellular activity, which is much more potent than the BCL9 peptide. Furthermore, enzymatic stability studies demonstrated the remarkable stability of the helical sulfono-γ-AApeptides, with no degradation in the presence of pronase for 24 h, augmenting their …
Human Origin Probiotic Lactobacillus Rhamnosus Hl-200 To Reduce Leaky Gut By Metabolizing Ethanolamine, Hariom Yadav, Shalini Jain, Sidharth Mishra
Human Origin Probiotic Lactobacillus Rhamnosus Hl-200 To Reduce Leaky Gut By Metabolizing Ethanolamine, Hariom Yadav, Shalini Jain, Sidharth Mishra
USF Patents
The present disclosure provides for a method of treating increased gut permeability, including administering a therapeutically effective amount of a human-derived probiotic to a patient in need thereof. Further provided herein is a method of increasing a patient's metabolism of ethanolamine, including administering a therapeutically effective amount of human derived probiotics to the patient in need thereof. Also provided herein is a pharmaceutical composition, including a first strain of Lactobacillus and a second probiotic strain. The present disclosure also provides for a pharmaceutical composition, including Lactobacillus and an antidiabetic drug. Additionally, provided herein is a pharmaceutical composition, including Lactobacillus and …
Be Your Own Brain Advocate: Why Older People Should Request Routine Cognitive Testing, Josey M. Batura, Elizabeth B. Fauth
Be Your Own Brain Advocate: Why Older People Should Request Routine Cognitive Testing, Josey M. Batura, Elizabeth B. Fauth
All Current Publications
Your primary care physician can conduct regular screenings and track cognitive changes; however, patients may need to advocate for and request testing. If there is noticeable loss in cognitive function, you may benefit from a more accurate diagnosis and a treatment plan or care plan from a medical specialist. Detecting cognitive changes early is better than knowing too late.
Tissue-Like Fracture Toughness And Stress–Relaxation Ability In Pva-Agar-Based Hydrogels For Biomedical Applications, Ismael Lamas Jr., Bhuvana L. Chandrashekar, Cláudia C. Biguetti, Mohammad R. Islam
Tissue-Like Fracture Toughness And Stress–Relaxation Ability In Pva-Agar-Based Hydrogels For Biomedical Applications, Ismael Lamas Jr., Bhuvana L. Chandrashekar, Cláudia C. Biguetti, Mohammad R. Islam
Mechanical Engineering Faculty Publications
Soft tissues exhibit remarkable stretchability, fracture toughness, and stress–relaxation ability. They possess a large water content to support cellular processes. Mimicking such a combination of mechanical and physical properties in hydrogels is important for tissue engineering applications but remains challenging. This work aims to develop a hydrogel that can combine excellent mechanical properties with cellular viability. The research focused on polyvinyl alcohol (PVA)/agar double-network (DN) hydrogels, fabricated by thermal gelation and freeze–thawing methods. Their mechanical properties were characterized through tension, compression, fracture, and stress–relaxation tests, and their cellular viability was measured through cytotoxicity tests. The results show that the PVA/agar …
Russian Arctic Land Forces And Defense Trends Redefined By Nato And Ukraine, Troy J. Bouffard, Lester W. Grau, Charles K. Bartles, Mathieu Boulègue
Russian Arctic Land Forces And Defense Trends Redefined By Nato And Ukraine, Troy J. Bouffard, Lester W. Grau, Charles K. Bartles, Mathieu Boulègue
The US Army War College Quarterly: Parameters
This article argues that Russia’s Arctic land forces have been weakened by the Russia-Ukraine War and NATO’s northern expansion, creating a strategic window for Western militaries to bolster their Arctic capabilities. Unlike existing studies that focus on maritime operations and the Northern Sea Route, it integrates technical assessments of ground-based Arctic platforms with analysis of military-district reforms. Using a mixed methodology that incorporates equipment specifications, Russian government documents, media reports, and NATO strategic-response evaluations, this article constructs a comprehensive baseline understanding of Russia’s Arctic land-force potential and readiness. Policy and military practitioners will benefit from actionable insights into Arctic force-design …