Digital Commons Network^™

Functional Vs Anatomical Cortico-Striatal Connectivity In The Macaque Brain, Ana M G Manea, Fernando A Ortega, Damyan Hart, Jason Zhou, Jan Zimmermann, Sarah R Heilbronner

Faculty, Staff and Students Publications

The cerebral cortex provides the main input to the striatum, constituting the first step in cortico-basal ganglia loops. Decades of careful anatomical tract-tracing research have established the exquisite topography of each cortical region's projection to the striatum in nonhuman primates. In parallel, neuroimaging research has demonstrated the relationship between cortico-striatal resting-state functional connectivity and specific cognitive, behavioral, psychiatric, and neurological states in humans. However, still unclear is the extent to which functional connectivity recapitulates the specific topographies of cortico-striatal anatomical connectivity. Here, we combined datasets of cortico-striatal anatomical and functional connectivity in macaques to determine the degree of overlap between …

A Mouse Model Of Lipoatrophy Reveals Relationships Between Beige Fat Appearance And Female Fertility, Aaron R Cox, Evelyn De Groot, Avery A Ahmed, Jessica B Felix, Bokai Zhu, Stephanie A Pangas, Sean M Hartig

Faculty, Staff and Students Publications

White adipose tissue (WAT) performs vital metabolic and endocrine functions, but roles in female reproduction remain understudied and poorly understood. Here, we report that female mice experiencing progressive lipoatrophy after knockout of Ubc9 in adipocytes (Ubc9fKO) displayed disrupted estrous cycles, reduced ovarian reserve, and subfertility. During aging, female Ubc9fKO mice lose subcutaneous WAT more quickly than their male counterparts and weigh less than littermate controls. Subcutaneous WAT excised from female Ubc9fKO mice strongly enriched for thermogenesis genes generally associated with metabolic benefits. Female Ubc9fKO mice exhibited hypermetabolism and accumulated thermogenic, Uncoupling Protein 1-expressing beige fat cells in residual subcutaneous WAT …

Create @ State 2011, Arkansas State University - Jonesboro

Create@State

The proceedings book for 2011

Exploring The Intricate Relationship Between Automation And Performance In The Saudi Public Sector., Saleh Hamed Alharbi

UB Journal for Humanities

Office automation immensely enhances the working environment. Widespread technological revolution shapes Human Resource Management (HRM) practice. The most important factor in decision-making is the information on which the decision is based. Detailed and accurate information prevents erroneous decisions. This study explores the impact of the automation of HR processes on organizational performance in the public sector. Three hundred and sixteen (316) employees from the University of Tabuk participated in the study. The study used smart Partial Least Squares–Structural Equation Model (smart PLS-SEM) to estimate the relationships between constructs. The results reveal that office automation has a direct impact on organizational …

2025 Program Book, Kari Harris

Arkansas Liberal Arts and Humanities Day

The program book for the inaugural Arkansas Liberal Arts and Humanities Day held on November 13th, 2025 in the Arkansas State Capitol building in Little Rock.

Ancient Chivalry And Modern Masculinity, Henry Jones Jones

Arkansas Liberal Arts and Humanities Day

I’m dissecting toxic masculinity in society through the lens of chivalry, as shown in Sir Gawain and the Green Knight. Knights were held to a code of chivalry that they used to interact with others and to wage war, a code heavily on display within the text of Sir Gawain. I’ve expanded into the fields of psychology, biology, and warfare to determine if there is a link between ancient chivalry and how men act today.

Ecology Of Subaerial Algae: Photosynthetic Capacity As A Function Of Relative Humidity In A Naturally- Occurring Association, James A. Nienow

Georgia Journal of Science

Subaerial algae are defined by their ability to grow on surfaces exposed directly to the air. We are currently investigating the nature of the adaptations that allow these unicellular microorganisms to form rich growths in an environment subjected to repeated and prolonged periods without liquid water. It is well known from laboratory studies that at least some members of the group are able to sustain metabolic activity using water vapor at high relative humidity. However, data concerning the significance of this ability in natural populations are almost completely lacking. To help fill in this gap, we tracked the photosynthetic capacity …

'The Rest Is Silence': Reframing Stasis As Integral To Creative Practice, Corinna Di Niro, Pablo Muslera

Staff Scholarship - Australia & Dubai

This duoethnographic study examines the relationship between motion and stasis in creative practice through the lens of two creative educators working in postgraduate and undergraduate Creative Industries. Drawing on our combined experiences as practitioners and educators at SAE University College, we explore how creative blockages can be reframed as productive rather than problematic, challenging dominant productivity paradigms in contemporary creative industries and education. Through structured dialogic exchange, we investigate three interconnected themes: the rhythmic nature of creative practice, the pedagogical value of embracing productive stasis, and the tension between institutional timelines and creative development. We consider how encouraging SAE creative …

Conquer And Prevail Issue 202 December 4 2025, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

Protein-Protein Interaction–Interfering Peptide Rescues Dysregulated Nmda Receptor Signaling, Robert E. Featherstone, Hongbin Li, Ameet S. Sengar, Karin E. Borgmann-Winter, Olya Melnychenko, Lindsey M. Crown, Ray L. Gifford, Felix Amirfathi, Anamika Banerjee, Aivi Tran, Krishna Parekh, Margaret Heller, Wenyu Zhang, Robert J. Gallop, Adam D. Marc, Pragya Komal, Michael W. Salter, Steven J. Siegel, Chang-Gyu Hahn

Farber Institute for Neuroscience Faculty Papers

The complex and heterogeneous genetic architecture of neuropsychiatric illnesses compels us to look beyond individual risk genes for therapeutic strategies and target the interactive dynamics and convergence of their protein products. A mechanistic substrate for convergence of synaptic neuropsychiatric risk genes are protein-protein interactions (PPIs) in the N-methyl-D-aspartate receptor (NMDAR) complex. NMDAR hypofunction in schizophrenia is associated with hypoactivity of Src kinase, resulting from convergent alterations in PPIs of Src with its partners. Of these, the association of Src with PSD-95, which inhibits the activity of this kinase in the NMDAR complex, is known to be increased in schizophrenia. Here, …

December 2025 General Education Council Minutes, University Of Nebraska At Kearney General Education Council

General Education Council

No abstract provided.

Toward Understanding Multi-Agent Decision Making In Complex Societies, Jonathan Skaggs

Theses and Dissertations

This dissertation investigates Multi Agent Decision Making (MADM) within Complex Societies (CS), systems of interdependent agents whose collective behaviors emerge from local interactions. Such emergent dynamics are nonlinear and difficult to predict, posing significant challenges towards understanding how individual decisions scale to societal outcomes. Existing approaches often fall short of capturing the combined attributes of CS, including asymmetry, decentralization, and adaptivity. To address this gap, we introduce new models and analyses of agent strategies that explain how cooperation and stability can arise in CS. Structured around three interrelated projects, this dissertation enhances our comprehension of MADM in CS. The research …

Curriculum Subcommittee Agenda December 4, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes - November 6, 2025
• R401 - Program Proposals
• Other Business
• Catalog Updates
• CIP Codes
• Adjourn 3:00 pm

Educational Policies Committee Minutes December 4, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes - November 6, 2025
• Subcommittee Reports
• Center for Civic Excellence Updates
• Other Business
• Adjourn: 3:15 pm

Curriculum Subcommittee Minutes December 4, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes - November 6, 2025
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:02 pm

Educational Policies Committee Agenda December 4, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes - November 6, 2025
• Subcommittee Reports
• Other Business
• Adjourn: 4:00 pm

Facility Usage On The International Space Station, Justin St. P. Walsh, Rao Hamza Ali, Ryan Shihabi, Erik Linstead

Art Faculty Articles and Research

Science experiments on the International Space Station (ISS) and in future space habitats require “facilities,” as they are known to space agencies, as the core building blocks of the research capabilities they provide. Facilities are experimental apparatus that enable research, often (but not always) used for more than one experiment, such as centrifuges, furnaces, gloveboxes, freezers, and more. The US Orbital Segment of the ISS has been home to 191 such facilities, belonging to four of the five ISS international partner agencies as well as private companies, in its 25 years of continuous operation. Until now, there has been no …

Parental Uncertainty And Information Needs For Children With Developmental Disabilities, Heejung Choi

Biennial Convention (CONV)

Background: Parents of children with developmental disabilities experience persistent and multifaceted uncertainty, starting with the initial recognition of developmental issues and continuing throughout their child’s life (Chao et al., 2018; Sartore et al., 2021; Scherr et al., 2020). Understanding what information can reduce uncertainty is crucial for alleviating stress and improving the well-being of both parents and their children with developmental disabilities (Smythe et al., 2021).

Aim: This qualitative study aimed to address the gap in identifying the most effective information for reducing parental uncertainty across different life stages of such children.

Method: This study employed a qualitative design. In-depth …

The Effects Of Emotional Valence On Memory In Garden-Path Sentences, William Banks Mangold

Honors Capstone Projects and Theses

No abstract provided.

What My Church Mother Taught Me: A Phenomenological Exploration Of The Maternal Messages Given To Black Christian Women On How To Cope With Trauma, Melanie Joyce Coates

Doctoral Dissertations and Projects

The purpose of this qualitative phenomenological study was to explore the lived experiences of Black women in Churches of Christ as they perceive and interpret maternal messages about coping with and managing the effects of traumatic experiences. For this study, maternal messages was defined as advice, support, mentorship, or guidance from older Black Christian women to younger Black Christian women. It was important to understand the ways in which older Black women teach younger Black women in navigating mental health challenges within the context of a complex trauma history among African Americans. The first theory that guided this study was …

Academic Opportunities: A Phenomenological Study Of The Lived Experiences Of Principals That Foster Academic Achievement Of Students That Attend Secondary Title I Schools, Loretta O'Nita Speller

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study is to explore the lived experiences of principals fostering the academic achievement of students in grades six through twelve who attend public secondary, Title I schools. The theory guiding this study was Maslow’s Hierarchy of needs. Maslow’s theory posits that if a person’s lower-level deficiency needs are not met, ascension to higher levels cannot happen. The central research question is: “What are the lived experiences of principals that lead secondary Title I schools and how do they foster academic achievement of their students?” Purposeful sampling was used in this study, and participants in …

The Divine Disciplinarian: God As The Model Father, Jacob Daniel Jones

Doctoral Dissertations and Projects

A pastor is responsible for instructing a congregation regarding biblical information and instruction. When a person is unsure of what the Bible teaches on a topic, the pastor can preach sermons and teach lessons that convey biblical truth. The growing congregation of Nevada Free Will Baptist Church consisted of believers who had been away from church for some time and new converts, resulting in a lack of biblical literacy due to their limited exposure to biblical truth. One area where congregants were uninformed was biblical parenting. This study addressed the problem of biblical illiteracy regarding parenting. It informed participants about …

Exploring The Experience Of East African Immigrants With Accents In Michigan Mental Health Counseling, Ermias Kebede Tessema

Doctoral Dissertations and Projects

This qualitative phenomenological study explored the lived experiences of East African immigrants with accented English in Michigan mental health counseling context. The purpose was to understand how accented speech shaped communication, emotional safety, and therapeutic connection between clients and counselors. Grounded in B.F. Skinner’s theory of language learning, along with the language transfer and critical period hypothesis frameworks, the study employed semi-structured interviews with ten East African immigrant adults who had received mental health counseling in Michigan. Data analysis produced five overarching themes: (1) Accent as a Communication Barrier, (2) Counselor’s Cultural Competence, (3) Emotional Experience of Counseling with an …

Comprehensive Analysis Platform To Understand, Remedy, And Eliminate Amyotrophic Lateral Sclerosis (Capture Als): Study Protocol For A Canadian Multicenter, Multimodal, Longitudinal Observational Study, Natalie Saunders, Claire Magnussen, Hyungmo Kang, Mathieu Blais, Harpreet Bhinder, Gerald Pfeffer, Shelagh K. Genuis, Liziane Bouvier, Tanushka Anand, Tania M. Bubela

Office of the Provost

Background: The marked heterogeneity of Amyotrophic Lateral Sclerosis (ALS) combined with a lack of biomarkers are key contributing factors to the lack of disease-modifying treatments. The Comprehensive Analysis Platform to Understand Remedy and Eliminate ALS (CAPTURE ALS) is a Canadian platform designed to create the most comprehensive picture of people living with ALS with the objective of facilitating ALS research initiatives worldwide.
Objectives: The main aims of CAPTURE ALS include: (1) to characterize ALS and healthy controls with biosamples and data in order to provide the most comprehensive picture of individuals living with ALS to date; (2) to create a …

Discovery Of A Small Molecule Tlr3 Agonist Adjuvant, Branden Lee, Danica Dong, Etsuro Nanishi, John Mark Awad, Kimia Abedi, Yoshine Saito, Francesco Borriello, Soumik Barman, Byron Brook, Aisling Kelly, Manisha Menon, Constance Marques-Mourlet, Maansi Gupta, Ida Lister, Chiwoo Oh, Kevin Lyskawa, Morgan Goetz, Kristina Walker, Wing Ki Cheng, Spencer Brightman, Pankaj Sharma, Timothy O'Meara, Katherine Chew, Daniel Vieira, Kevin Ryff, Cali Sweitzer, Sanya Thomas, Simon Van Haren, Matthew Pettengill, Hyuk-Soo Seo, Sirano Dhe-Paganon, Wei Zhang, Ofer Levy, David Dowling

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Pattern-recognition receptor (PRR) agonists are valuable agents across multiple medical applications, from vaccinology to immune-oncology. However, well-defined and potent small molecule agonists for many PRRs still await discovery and development. Screening of chemical libraries of ~200,000 small molecules for maturation of human monocytic cells by quantifying NF-κB activation and cell adherence was completed. From this screen, we selected a thiazole benzamide derivative, PVP-057, for its robust immunomodulatory properties, low toxicity profile, and concentration-dependent activity. In vitro investigation of pathway and receptor activation reveals that PVP-057 is a Toll-like receptor 3 (TLR3) agonist. As a single-component adjuvant, administered intramuscularly or intradermally …

The Divided Self: Gothic Duality In Literature, Sarah Anna Meeks

Masters Theses

Gothic literature of the nineteenth century is haunting due to its frequent use of ghosts and monsters. However, the true terror lies in a deeper horror, one that is more intimate and destabilizing– a fright that leaps out of the text, looking into the heart of the reader: the fractured mind of the self torn between reality and repression, haunted by its own, newly manifested internal disunity rather than external monsters. The characters of Gothic fiction are typically caught in a psychological turmoil. They battle with split morals between duty and desire, morality and madness, and science and spirituality. Specifically, …

A Concept Analysis Of Entrenched Toxic Cultures In Nursing Academia, Becky Good, Kristen Kirby, Karen J. Foli

Biennial Convention (CONV)

Introduction: Toxic cultures in nursing academia are environments characterized by incivility, bullying, and harassment, all concepts well defined in the literature (Beckmann et al., 2013; Clark, 2013; Fry & Schmer, 2021). While some toxic cultures can be addressed with targeted interventions, others are more widespread, established, and difficult to dismantle (Beitz & Beckmann, 2023; Clark & Ritter, 2018; Coates, 2024; Goldberg et al., 2013; Olsen et al., 2020). Specific data are scarce; however, as negative behaviors persist and intensify, we believe the unexplored phenomenon of entrenched toxic culture (ETC) emerges.

Purpose: This concept analysis aims to define ETCs in nursing …

Automated Detection Of Kinky Back In Broiler Chickens Using Optimized Deep Learning Techniques, Ramesh Bahadur Bist, Andi Asnayanti, Anh Dang Trieu Do, Yang Tian, Chaitanya Palleria, Dongyi Wang, Adnan Alrubaye

Food Science Faculty Publications and Presentations

The global poultry industry faces growing challenges from skeletal disorders, with Kinky Back (KB) significantly impacting broiler welfare and production. KB causes spinal deformities that reduce mobility, feed access, and increase mortality. It often remains undetected in early subclinical stages. Traditional KB diagnosis methods are slow and subjective, and highlighting the need for an automated and objective detection. This study develops a machine learning approach for detecting KB in broilers using image data. Male Cobb 500 broilers were raised under controlled conditions and monitored over 7 weeks using overhead 4K video cameras. Behavioral and posture data related to KB were …

Spartan Daily, December 4, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 42

Historical Review: More Than Two Decades Understanding The Genetic Architecture Of Hemostasis And Thrombosis, Alisa S Wolberg, Andrew D Johnson, Nicholas L Smith

Faculty, Staff and Student Publications

From the beginning of the millennium and the development of genome-wide analyses, the technical advances and remarkable increase in research sample sizes have led to an escalating number of discoveries revealing genetic determinants of levels of the main factors regulating hemostasis and thrombosis and demonstrating a clear polygenic complex regulation of most coagulation factors. These discoveries have been useful to understand the biology underlying hemostasis regulation and to understand risk of associated thrombotic disease, such as venous thromboembolism, coronary artery disease, and ischemic stroke. In this historical review, we outline the main discoveries in genetic studies of coagulation factors (fibrinogen …