Digital Commons Network^™

Antibacterial Effect Of Moringa Oleifera Extract, Chitosan, And Calcium Hydroxide Against Porphyromonas Gingivalis: A Preliminary In Vitro Study, Adilah Zf. Djerman, Muhammad F. Sabirin, Erna A. Sutanto, Nisrina E. Nasrun, Maria Tanumiharja

Journal of Dentomaxillofacial Science

Objective: Given the role of Porphyromonas gingivalis in pulp inflammation and the potential of natural agents to enhance conventional medicaments, this study aimed to investigate the antibacterial activity of Moringa oleifera extract and chitosan, in combination with calcium hydroxide [Ca(OH)₂], against P. gingivalis

Material and Methods: The laboratory experiment used 12 groups with three replicates (36 samples in total). The groups included: (1) Moringa oleifera with Ca(OH)₂, (2) chitosan with Ca(OH)₂, and (3) M. oleifera, chitosan, and Ca(OH)₂ mixture. Each group had four subgroups: Ca(OH)₂ control and concentration ratios of 1:1, 1.5:1, and 2:1. Antibacterial activity was measured via disc …

Antibacterial Activity Of Ethanol Extract Of Cocoa Beans (Theobroma Cacao L): In Silico And In Vitro Study, Rudy Joelijanto, Rina Sutjiati

Journal of Dentomaxillofacial Science

Objective: This study was conducted to determine the minimum inhibitory concentration (MIC) of cocoa beans ethanol extract gel on Streptococcus mutans, and prediction interaction between the active compound of cocoa bean (Theobroma cacao L.) and the antibacterial protein in silico.

Various bioactive compounds including polyphenols have been found in cocoa beans, which have essential properties such as antibacterial effects. Material and Methods: The research was conducted in silico and in vitro study. The study was divided into 8 treatment groups and 4 repetitions. The sample group used was cocoa beans extract concentration of 25%; 12,5%; 6,25%; 3,12%; 1,56%; 0,78%; …

Comparative Analysis Of Groundwater Quality Based On Chemical Parameters Around Final Disposal Sites Using Open Dumping And Sanitary Landfill Methods, Shiesil Rizqia Amadia, Mika Vernicia Humairo

Preventia: The Indonesian Journal of Public Health

The main environmental issue at landfill sites is the seepage of leachate into the ground, which contaminates surrounding aquifers. Communities residing within one kilometer of landfill sites are at high risk of environmental pollution. This study aimed to analyze differences in groundwater quality around landfills applying open dumping and sanitary landfill methods, and to compare groundwater quality at safe and unsafe distances from these sites. The research was conducted around the Cipayung landfill in Depok (open dumping) and the Talangagung landfill in Kepanjen (sanitary landfill). The study adopted an analytical observational approach using a cross-sectional design. The independent variables included …

The Role Of Climate And Population Density In The Spread Of Dengue Fever: A Spatial Analysis Of Padang City 2022–2024, Nailul Hikmi, Aria Gusti

Preventia: The Indonesian Journal of Public Health

In 2023, Padang city had a dengue fever incidence rate of 46.5 per 100,000 population, an increase compared to the previous year. Climate change, with the transition from the dry to the rainy season, contributed to a surge in dengue fever cases. This study aims to determine the relationship between environmental factors and the incidence of dengue fever in Padang City from 2022 to 2024. This study uses an ecological study design with a sample of all dengue fever cases recorded by the Padang City Health Office. Climate data was obtained from the Indonesian Agency for Meteorological, Climatological, and Geophysical …

The Indonesian Guardianship And Indonesian Private International Law, Tiurma Mangihut Pitta Allagan, Dinda R. Himmah, Amirah Hisana

Indonesia Law Review

The increasing of number of cross-border legal relationships, especially family legal relationships, is inevitable. For instance, it is also commonly accepted for a foreign national to have a legal-bond with children from another country, which is also known as intercountry adoption, guardianship and fostership. This paper aims to analyze and classify guardianship involving international dimension within the jurisdiction of Indonesia. The examination of this legal question would be on the basis of Indonesian Private International Law (PIL). The choice of law and the choice of jurisdiction are the basic analysis, further, as to whether the guardianships are in line with …

Green Bonds As A Green Investment To Prevent Greenwashing And Green Financial Crime In Indonesia, Cita Yustisia Serfiyani

Indonesia Law Review

Overcoming the climate crisis should not only be pursued from the aspect of technological invention but also from the financial aspect through issuing securities instruments that align with the green economy mission. Unfortunately, irresponsible parties such as corporations still use the green economy concept for personal gain through greenwashing and green financial crime. The presence of green bonds as green instruments shows a positive trend towards improving the quality of environmentally friendly technological innovations, building green infrastructure, and increasing income in line with increasing public participation in climate issues. However, its application in Indonesia is constrained by the complexity of …

Floating Nuclear Power Plants On The Horizon. Do We Need A Revised Brussels Convention On The Liability Of The Operators Of Nuclear Ships?, Jakub Handrlica

Indonesia Law Review

Adopted in 1962, the Brussels Convention on the Liability of the Operators of Nuclear Ships has been considered an obsolete instrument for the last 60 years. In light of renewed interest in floating nuclear power plants (FNPPs), this article revisits the regime of this half-forgotten Convention and calls for its modernisation. The fact is that a robust legal framework for liability and compensation must accompany any prospective deployment of FNPPs. This article argues that adopting a Revised Brussels Convention will help address these challenges. This article aims to identify the reasons for this modernisation and to outline its significant features. …

Penerapan Media Card Education Output Untuk Meningkatkan Keterlibatan Aktif Siswa Smp Pada Materi Mengapresiasi Kebudayaan Lokal, Thania Carolline, Abd. Mu'id Aris Shofa

Journal of Innovation and Teacher Professionalism

This study aimed to explore the use of various instructional media to support effective classroom learning. A qualitative descriptive case-study approach was employed. The participants were 30 Grade X students at SMP Muhammadiyah 01 Malang. Data were collected through classroom observations, interviews with teachers and students, and analysis of learning documents. Data were analyzed using the Miles and Huberman interactive model, which includes data reduction, data display, and conclusion drawing. The findings showed that the use of varied instructional media, including social media and digital technology, increased student engagement and enriched their learning experiences. Traditional instructional media also continued to …

Green Tea (Camellia Sinensis) And Cognitive Health: A Systematic Review Of Mechanisms, Clinical Evidence, And Neuroprotective Potential, Elisha Rosalyn Rosdah, Eka Febri Zulissetiana, Irfannuddin Irfannuddin

Folia Medica Indonesiana

Cognitive decline, often a precursor to neurodegenerative diseases like Alzheimer's, is a growing global health challenge. Green tea (Camellia sinensis), rich in bioactive compounds such as epigallocatechin-3-gallate (EGCG) and L-theanine, has demonstrated promise in supporting cognitive function and reducing cognitive decline. This systematic review evaluated the recent evidence on the effects of green tea on cognition and its underlying mechanisms. The authors conducted a comprehensive search of PubMed, SpringerLink, and ScienceDirect for open-access articles published between January 2020 and April 2025. This systematic review included studies examining the impact of green tea on cognitive function in humans and …

Kegagalan Kepastian: Membingkai Ulang Manajemen Strategis Melalui Kompleksitas, Brian Hoffni

Jurnal Manajemen dan Usahawan Indonesia

This paper explores the integration of complexity theory into the field of strategic management, arguing that traditional, positivist-based models—such as the planning school, positioning school, and resource-based view—are increasingly inadequate for addressing the volatility, uncertainty, complexity, and ambiguity (VUCA) of contemporary business environments. While classical theories emphasize linearity, stability, and top-down control, complexity theory reconceptualizes organizations as complex adaptive systems (CAS) characterized by emergence, nonlinearity, and continuous learning. Drawing on insights from both historical and contemporary strategic paradigms, this study proposes that complexity theory does not replace but rather extends classical frameworks by enabling more adaptive, iterative, and resilient approaches …

Efektivitas Pendekatan Teaching At The Right Level (Tarl) Dalam Meningkatkan Hasil Belajar Siswa Kelas V Sekolah Dasar, Nur Azlina, Putri Rohadatul Aisy, Siti Mas'ula

Journal of Innovation and Teacher Professionalism

This study aimed to analyze the effectiveness of the Teaching at the Right Level (TaRL) approach in improving learning outcomes in Natural and Social Sciences among Grade V students at SDN Sawojajar 5 Malang. It used a quantitative pre-experimental method with a One-Group Pretest–Posttest design. The participants were 28 students from Grade V-A selected through purposive sampling. Data were collected using pretest and posttest instruments as well as observation. The average pretest score was 60.36, while the average posttest score after the TaRL intervention was 91.43. Hypothesis testing produced a Sig. (2-tailed) value of 0.000, lower than 0.05, indicating that …

Pemanfaatan Nearpod Sebagai Media Pembelajaran Matematika Berbasis Gamifikasi Pada Materi Segitiga Dan Segi Empat Kelas Viii Smp, Intan Faraminda Putri, Erry Hidayanto, Sri Indayani

Journal of Innovation and Teacher Professionalism

Low student motivation is a major challenge in education today, particularly in mathematics. One solution is to use gamification-based instructional media such as Nearpod. The application offers interactive features, including quizzes, polls, simulations, and dynamic presentations, which can create an enjoyable and engaging learning environment. This study employed a qualitative approach to explore the benefits of using Nearpod in mathematics instruction. The participants were 32 students in Grade VIII-H at SMPN 18 Malang. Data were collected through open-ended surveys and observations of student activities during lessons. The findings showed that Nearpod improved students’ understanding of triangles and quadrilaterals, created a …

Characterization And Biocompatibility Test Of Chitosan-Alginate-Fucoidan Hydrogel As Potential Socket Preservation Material: In Vitro Study, Ainiyyah F. Zaizafun, Nurlindah Hamrun, Erni Marlina, Lenni Indriani, Nurhayaty Natsir, Asdar Gani, Arifin

Journal of Dentomaxillofacial Science

Objective: This study aimed to characterize and evaluate the in vitro biocompatibility of chitosan-alginate-fucoidan hydrogel at different concentrations as a potential socket preservation material.

Material and Methods: Hydrogels were prepared using various concentrations of chitosan-alginate-fucoidan formulas. Alginate and fucoidan which were extracted from brown algae, were dissolved in purified water with stirring, then mixed with chitosan from white shrimp skin, which was prepared in 2% acetic acid. The hydrogels were characterized using scanning electron microscopy (SEM) and Fourier transform-infrared spectroscopy (FTIR). Biocompatibility was assessed using KUSA cells through cell viability, cytotoxicity, and cell adhesion. Data were analyzed using a one-way …

Serum Level Of Il-4 And Il-13 And Their Association With Disease Pathogenesis In Patients With Eczema, Shurooq Salim Murad, Heyam Qaid Mohammad

Al-Qadisiyah Medical Journal

Background: As the most common chronic skin illness with a genetic foundation, eczema is an inflammatory skin condition driven by cytokines. People with AD suffer from a significant burden that affects their physical, mental, social, and financial well-being.  The cytokines are important in eczema disease. Interleukins regulate immunity. Lack impairs immunity or causes autoimmune disorders. Objectives: This study is aiming to investigate whether inflammatory cytokine (IL-4, IL-13) levels in the blood correlate with eczema disorder. Methods: This case-control study is based on 60 patients who have been diagnosed with eczema disorder with a 60-person apparently healthy control group. 4 ml …

Investigating The Role Of Cornichon-Homolog 3 (Cnih3) In Opioid Use, Contributing Risk Factors, And Associated Neural Substrates, Tania Lintz

Arts & Sciences Graduate Student Theses and Dissertations

Opioid misuse remains rampant as potent synthetic opioids such as fentanyl flood the market. Large-scale genetic tools like the GWAS identify previously unrecognized targets and biomarkers in opioid misuse with the hopes of combating the opioid epidemic and opioid use disorder (OUD). One such target is the AMPA receptor (AMPAR) auxiliary protein Cornichon Homolog-3 (CNIH3), which determines AMPAR subunit composition and kinetics. Though CNIH3 was identified as a gene of interest in OUD, its role in opioid use and accompanying risk factors has not been studied. Using mice with a CNIH3 deletion, we assess the role of CNIH3 in risk …

Relationships Between Larval Fish Drift, Time Of Day And Discharge In An Ozark Stream, Daniel D. Magoulick, Christy L. Graham

Biological Sciences Faculty Publications and Presentations

We examined the relationship between larval fish numbers and discharge during a high flow event in Bear Creek, Arkansas, a small Ozark stream. Additionally, we examined the relationship between fish numbers and time of day, and the spatial distribution of families and size classes. A total of 3,083 fish from five families were collected. Leuciscidae was the dominant family collected, followed by Percidae, and Catostomidae. Larval fish in Bear Creek were not susceptible to increased discharge from the flood event, as all three families exhibited strong significant negative relationships to discharge at night when discharge began to decline. Larval fish …

Centering Ai Literacy: Exploring Brazilian International Students’ Perceptions Of Chatgpt And Peer Tutoring, Leigh Ann Dunning, Raissa Borges De Oliveira Leal

The Writing Center Journal

For English as an Additional Language (EAL) students, generative AI (GenAI) offers meaningful support for writing in English, while also introducing a new set of challenges. Supporting EAL students in developing AI literacy is crucial to their growth as confident, adaptable writers, and writing center tutors are uniquely positioned to facilitate this development. This case study explores the experiences of undergraduate Brazilian international students at a small liberal arts college who received writing feedback from both peer writing center tutors and ChatGPT. Findings indicate that students valued the human connection, contextual understanding, and rhetorical support offered by peer tutors, while …

The Landscape Of Silver Diamine Uoride Research In Dentistry: A Bibliometric Analysis Of Trends And Future Directions, Wong F. Jak, Tengku Nnt. Hamzah, Thaddius H. Maling, Nor Am. Nor

Journal of Dentomaxillofacial Science

Objective: To update the bibliometric profile of global SDF literature, focusing on publication trends, contributing countries, study designs and mapping thematic research evolution.

Material & Method: Publications were searched in the Scopus database from inception to 20 April 2025. Data were extracted and cleaned using biblioMagika® and OpenRefine. Study designs were manually classified through abstract review. Publication trends were analysed using SPSS software. Data visualisations were generated using VOSviewer and Biblioshiny.

Results: Of 727 records identified, 659 publications were included in the analysis. Laboratory studies (45.83%) dominated, followed by clinical trials (19.58%) and reviews/guidelines (15.78%). Publication output rose modestly until …

Post–Tooth Extraction Supportive Therapy With Limosilactobacillus Reuteri Probiotic And Hyaluronic Acid Gel Combination On Collagen Density, Desak Mh. Wijayanti, Armelia S. Widyarman, Melanie H. Sadono, Firstine K. Hartanto, Komariah, Wiwiek Poedjiastuti

Journal of Dentomaxillofacial Science

Objective: Tooth extraction is a common medical procedure that can be classified classified as simple or complex, depending on the condition of the tooth. Supportive therapies are being explored to  accelerate wound healing after tooth extraction. Hyaluronic Acid (HA) and Limosilactobacillus reuteri (L. reuteri) are known to have positive effects on overall body and oral health. This study aimed to analyze the differences in collagen density during wound healing process after tooth extraction with the administration of supportive therapy by combining HA and probiotic L. reuteri in Wistar rats (Rattus norvegicus).

Material and Methods: Collagen density …

Combined Effects Of Physical Activity And Uv-B Light On Bdnf In Brain And Oral Function: A Wistar Rat Model Study, Zahreni Hamzah, Tantin Ermawati, I-Dar. Dewanti, Sari Setyaningsih, Yohana M. Penga, Julia Yp. Ariyo

Journal of Dentomaxillofacial Science

Objective: To evaluate the combination effects of physical activity (structured training) and UV-B exposure on serum brain-derived neurotrophic factor (BDNF) levels and assess their association with oral health and cognitive function.
Materials and methods: This study utilized male Wistar rats (3-4 months old, average body weight 250-350 g). The rats were divided into three groups: (K) control group and (P) exercise groups with or without ultraviolet B (UV-B) exposure. The exercise-treated groups underwent treadmill running for 30 minutes per session, divided into three sessions. Following the intervention, the rats were euthanized, and intracardiac blood samples (5 mL serum per rat) …

Quality Evaluation Of Ecological Experience Resources And Optimization Of Resource Management Policies In National Parks: Taking The Laohegou Area Of Giant Panda National Park As An Example, Baorong Huang

Double Helix Methodology

National parks are the core carriers for implementing the concept of “ecological protection first, public welfare for all”. This study used the fuzzy comprehensive evaluation method to evaluate the ecological experience resource quality of the Laohegou area in Giant Panda National Park of China. Based on the standardized psychological assessment scale and the Kessler Psychological Distress Scale, we have established an evaluation model for the psychological health benefits, quantifying the psychological health benefits of tourists in the ecological experience of national parks. At the same time, the relationship between the demographic characteristics, ecological experience characteristics, psychological health level, and psychological …

A Novel Rheological Technique To Measure The Yield Stress In Equibiaxial Elongation, Asher Segal

Theses

Yield stress measurement in non-Newtonian fluids, particularly under complex flow conditions such as equibiaxial elongation, remains a significant challenge in experimental rheology. This work presents the development of a novel method, Continuous Lubricated Squeezing Flow (CLSF), designed to quantify the normal yield stress of viscoelastic materials while minimizing boundary artifacts.

The CLSF method was implemented and validated using Carbopol 940, a model yield-stress gel, at concentrations of 1 wt% and 2 wt%. Comparative shear rheology was first performed to establish baseline yield stresses and verify sample integrity. CLSF experiments were then conducted over controlled flow rate increments and gap distances …

Construction And Data-Driven Analysis Of A Stochastic, Individual-Based Opioid Epidemiology Network Model, Leigh Bennett Pearcy, Owen Queen, Vincent Jodoin, Suzanne Lenhart, Christopher Strickland

Mathematical Modelling and Numerical Simulation with Applications

While substance use epidemiology has been an active area of mathematical research in recent years, the social and mental processes that are involved in the development of substance use disorders have presented challenges to advancing the epidemiological theory and how they differ from the contraction of pathogenic disease. Such distinction is especially pertinent in the context of the current United States opioid epidemic and its intersection with the recent COVID-19 pandemic, as both prescription drugs and social influence play major roles in the development of opioid use disorder. In this paper, we construct a stochastic network model capturing how individual …

Analysis And Numerical Investigation Of A Breast Cancer Treatment Model Incorporating Ketogenic Diet And Immune Boosters Via Optimal Control Theory, Kunnisai Muniroh, Ummu Habibah, Wuryansari Muharini Kusumawinahyu, Nur’Izzati Hamdan

Mathematical Modelling and Numerical Simulation with Applications

This paper develops a mathematical model to investigate breast cancer dynamics by incorporating tumor–immune interactions, ketogenic diet effects, and medical treatment. The model is formulated as a system of nonlinear ordinary differential equations and analyzed within an optimal control framework. Time-dependent control variables are introduced to represent treatment strategies aimed at minimizing tumor progression while reducing therapeutic costs. The model’s well-posedness is established through positivity and boundedness analysis. The necessary conditions for optimality are derived using Pontryagin’s Minimum Principle, resulting in a coupled system of state and adjoint equations. Numerical solutions are obtained using the fourth-order Runge–Kutta method combined with …

Opening Paths: Subjective And Professional Trajectories In Psychosocial Intervention For Victims Of The Armed Conflict In Colombia, Edwin Alexander Hernandez Zapata, Diana Vanessa Vivares Porras, Juan David Soto-Fadul

The Qualitative Report

In this study, we analyzed the affective experiences and labor subjectivation processes of community psychologists working in intervention programs implemented by state institutions in Colombia for victims of the armed conflict, a conflict that remains ongoing in various regions of the country. By labor subjectivation processes, we refer (drawing on Foucault) to the ways in which individuals come to relate to themselves and to others through the norms, discourses, and practices that shape their roles within a given historical and institutional context—in this case, the field of psychosocial labor. To conduct this research, we used discourse analysis and semi-structured interviews …

Associations Between Health-Seeking Behaviors And Social Support For Adult Black Women In The United States, Patricia Saint Cyr-Hager

Walden Dissertations and Doctoral Studies

A persistent gap exists involving health outcomes for Black women in the United States, regardless of socioeconomic status when compared to Black men and White women. This qualitative case study involved exploring the influence of social support on health-seeking behaviors among Black women. Sixteen participants, between ages 22 to 49 from nine states, were recruited. Data was collected using semi-structured interviews based on the social support theory. An analysis of the network composition showed that family members (including mothers, fathers, sisters, and partners), friends, community support groups not connected to social media, and online community support groups were the most …

The Association Between E-Cigarette Use And Community Mattering Among Adolescents In Maine, April Hughes

Walden Dissertations and Doctoral Studies

E-cigarette use among U.S. high school students is a significant public health issue. Factors such as mattering, sexual orientation, and gender identity (SOGI) influence e-cigarette use among adolescents, yet few studies have explored the relationship between mattering and e-cigarette use when considering SOGI. This quantitative study explored the association between past 30-day e-cigarette use and mattering among Maine high schoolers while controlling for SOGI and grade level. This correlational cross-sectional study used the 2023 Maine Integrated Youth Health Survey data, and the socioecological model served as the theoretical foundation. A multivariate binary logistic regression analysis indicated a significant association between …

Future Teachers’ Views On Their Science Teachers: A Case Of Turkey, Mehmet Karakaş

The Qualitative Report

Here future elementary and middle school teachers reflect on their experiences with science teachers encountered throughout their education and highlight their characteristics. The aim of the study was to create a program where teachers were given the explicit opportunity to reflect on their experiences through journaling that promoted reflective thought. Participants were 173 non-science and 120 science major prospective teachers enrolled in a small university in northeastern Turkey. Data were collected using document analysis. Findings show that effective science teachers do experiments, use teaching materials, and show special interest in students; also, their positive personality affected students’ positive attitude towards …

Investigation On The Effects Of Hypoxia-Mimicking Agents In Cancer Progression And Oxidative Stress In Hepatocellular Carcinoma, June Wong Xin Ni

Student Works (2020-2029)

Hypoxia, or oxygen deprivation, is a common pathological feature found in hepatocellular carcinoma (HCC). Hypoxia-inducible factor (HIF) is the master transcription factor of oxygen homeostasis, eliciting a wide range of cellular adaptive responses to either enhance oxygen delivery or reduce oxygen consumption. HIF is primarily regulated by two types of oxygen sensors, the prolyl hydroxylase domain-containing proteins (PHDs) and factor-inhibiting HIF (FIH). In tumours, HIF functions as a double-edged sword whereby it could either promote or hinder tumour progression. This is mainly contributed by the pleiotropic nature of hypoxia and tumour heterogeneity. Recently, there is a growing interest in the …

Gut Microbiome Metagenomics In Clinical Practice: Bridging The Gap Between Research And Precision Medicine, Henok Ayalew Tegegne, Tor C Savidge

Faculty, Staff and Students Publications

Gut microbiome metagenomics is emerging as a cornerstone of precision medicine, offering exceptional opportunities for improved diagnostics, risk stratification, and therapeutic development. Advances in high-throughput sequencing have uncovered robust microbial signatures linked to infectious, inflammatory, metabolic, and neoplastic diseases. Clinical applications now include pathogen detection, antimicrobial resistance profiling, microbiota-based therapies, and enterotype-guided patient stratification. However, translation into routine care is hindered by significant barriers including methodological variability, limited functional annotation, lack of bioinformatics standardization, and underrepresentation of global populations. This review synthesizes current translational strategies, emphasizing the need for hypothesis-driven designs, multi-omic integration, longitudinal and multi-center cohorts, and mechanistic validation. …