Digital Commons Network^™

Characterization Of Exercise-Associated Skeletal Muscle Secreted Factors Through Aging, Dalton Chase Patterson

All ETDs from UAB

Exercise is a powerful behavioral intervention against Central Nervous System (CNS) aging1–3 and plays an essential role in maintaining healthy neurocognitive function and immune metabolism in the aging brain3. We have developed a new transgenic mouse model that moderately over-expresses transcription factor master regulator of proteostasis, Transcription Factor E-B (TFEB), in skeletal muscle (cTFEB;HSACre mice). Despite living sedentary lifestyles, our model of enhanced skeletal muscle proteostasis shows significantly ameliorated proteotoxicity, increased BDNF levels and neurogenesis while improving neurocognitive function and decreasing neuroinflammation in the aging CNS4,5. These neuroprotective effects are markedly reminiscent of those observed in the aging CNS post-exercise6,7, …

Labor Union Membership Tenure And Midlife Health: A Gendered Perspective, Clifford Ross

All ETDs from UAB

The benefits of labor unions have not gone unstudied. Individuals in labor unions have better access to lower cost/more substantial health insurance plans, higher quality pension plans, and better wages leading to increased lifetime earnings. Even though many of these benefits create important pathways that could lead to better health, unions have been paid little attention in health literature. Additionally, in the modern workplace Mothers are offered lower starting salaries, are perceived as less competent, and face a penalty regarding hiring, promotion, and workplace educational opportunities. Compared to men, women with children see an income gap 20 cents wider than …

The Role Ofbiomechanics In Vascular Endothelial Growth Factor Receptor-2 Signaling, Bronte Miller

All ETDs from UAB

Angiogenesis, or the growth of new vasculature from existing blood vessels, is widely considered a primary hallmark of cancer progression. When a tumor is small, diffusion is sufficient to receive essential nutrients; however, as the tumor grows a vascular supply is needed to deliver oxygen and nutrients into the increasing mass. Several anti-angiogenic cancer therapies target VEGF and its receptor VEGFR-2, which are major promoters of blood vessel development. Unfortunately, many of these cancer treatments fail to completely stop angiogenesis in the tumor microenvironment (TME). Since these therapies focus on the biochemical activation of VEGFR-2 via VEGF ligand binding, we …

Low-Dose Dextromethorphan For The Treatment Of Pain In Fibromyalgia: A Single-Blind Placebo-Controlled Crossover Trial, Stephanie Christina Mueller

All ETDs from UAB

Fibromyalgia (FM) is a debilitating chronic pain condition. Its pathophysiology is largely unknown, which has hindered the development of effective treatments. Central sensitization and neuroinflammation have been forwarded as models of FM pathophysiology, both of which indicate the antitussive drug dextromethorphan (DXM) as a potentially effective treatment. DXM is an N-Methyl-D-aspartic acid (NMDA)-receptor antagonist and microglial modulator with anti-neuroinflammatory properties at low doses. It is currently available for clinical use, but has not been tested as a treatment for FM at low dosages. The current study evaluated the effectiveness of DXM in treating FM-associated symptoms of pain, fatigue, cognitive problems, …

Eagle Executive Magazine, Georgia Southern University

College of Business: News & Publications

• From the Desk of Dean Amason
• College News
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• Feature: Parker College Welcomes Newest Carter Chair
• Graduate Programs
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Eagle Accountant, Parker College Of Business

College of Business: News & Publications

No abstract provided.

Assessing The Biological Performance Of Living Docks—A Citizen Science Initiative To Improve Coastal Water Quality Through Benthic Recruitment Within The Indian River Lagoon, Florida, Morgan Gilligan, Kelli Hunsucker, Sandra Rech, Alyssa Sharma, Ryan T. White, Robert Weaver

Mathematics and System Engineering Faculty Publications

Like many estuaries worldwide, the Indian River Lagoon (IRL), has seen a decline in resources and overall water quality due to human activities. One method to help restore water quality and benthic habitats is to construct and deploy oyster restoration mats on dock pilings, known as the Living Docks program. This community-driven program was founded to promote the growth of filter-feeding benthic organisms and improve local water quality. The purpose of this study was to assess the growth and performance at four of the Living Dock locations and to provide feedback to the citizens who were involved in the initial …

Epidemiological Models, Parameters, And Prediction Of The Covid-19 Outbreak In A Southwest Georgia Hotspot, Daniel F. Linder, William M. Sewell Iii, Jack D. Owens, Jim Franklin, Mark Miller, Casey Newton, Priyank Shah

Journal of the Georgia Public Health Association

Background: We investigate epidemiological models, their parameters, and the models’ predictive performance of daily new cases during the first three weeks of the SARS-CoV-2 outbreak in a southwest Georgia hotspot.

Methods: We fit stochastic versions of the classical SIR, a network-based SIR, an SEIR model with two different priors on the latent period rate parameter, and a simple doubling time model to SARS-CoV-2 patients’ date of hospital admission and length of symptoms data from the Phoebe Putney Health System.

Results: The estimated basic reproductive numbers and 95% Bayesian credible intervals for each of the models were: 1.98 (1.63, 2.45) for …

¿Tú Qué Sabes?: Latina Doctoral Women Disrupting And Resisting Dominant Knowledge, Sendy Ramos Madsen

Doctoral Dissertations

Education environments have systematically excluded, silenced, and erroneously spoken on behalf of Women of Color. Linear forms of scholarship and research practices propagate the dominant perspective and fail to address systems of oppression that result in epistemic suppression and academic hostility towards brown minds. Historically, Latina women have not been seen as creators of knowledge, and their access to educational spaces has been restricted. According to census projections, in 2036, Latinas/os will account for the largest minority group in the United States and one-third of the American educational system. Therefore, academic spaces must establish practices to include Latina women as …

Near-Infrared Spectroscopy Estimation Of Combined Skeletal Muscle Oxidative Capacity And O2 Diffusion Capacity In Humans, Andrea M. Pilotto, Alessandra Adami, Raffaele Mazzolari, Lorenza Brocca, Emanuela Crea, Lucrezia Zuccarelli, Maria A. Pellegrino, Roberto Bottinelli, Bruno Grassi, Harry B. Rossiter, Simone Porcelli

Kinesiology Faculty Publications

The final steps of the O2 cascade during exercise depend on the product of the microvascular-tointramyocyte PO2 difference and muscle O2 diffusing capacity (DmO2). Non-invasive methods to determine DmO2 in humans are currently unavailable. Muscle oxygen uptake (mVO2) recovery rate constant (k), measured by near-infrared spectroscopy (NIRS) using intermittent arterial occlusions, is associated with muscle oxidative capacity in vivo. We reasoned that k would be limited by DmO2 when muscle oxygenation is low (kLOW), and hypothesized that: i) k in well-oxygenated muscle (kHIGH) is associated with maximal O2 flux in fiber bundles; and ii) Δk (kHIGH-kLOW) is associated with capillary …

A Crew-Operated Data Recording System For Length-Based Stock Assessment Of Indonesia’S Deep Demersal Fisheries, Elle Wibisono, Peter Mous, Edwison Firmana, Austin T. Humphries

Fisheries, Animal and Veterinary Sciences Faculty Publications

Deep demersal fisheries in Indonesia yielded close to 90,000 metric tons of snapper and grouper in 2019, landed by a fleet of approximately 10,000 fishing boats. Prior to the present study, information on these multi-species, dispersed, small- to medium-scale fisheries was scarce, while reliable species-specific data on catch and effort were non-existent. This data-deficiency made stock assessments and design of harvest control rules impossible. We developed a new data collection method, the Crew Operated Data Recording System (CODRS), to collect verifiable species- and length-composition data from catches across all segments of the fleet. CODRS engaged crews of 579 fishing vessels …

Diversity And Distribution Of Symbiodiniaceae Detected On Coral Reefs Of Lombok, Indonesia Using Environmental Dna Metabarcoding, Arief Pratomo, Dietriech G. Bengen, Neviaty P. Zamani, Christopher E. Lane, Austin T. Humphries, Erin Borbee, Beginer Subhan, Hawis Madduppa

Fisheries, Animal and Veterinary Sciences Faculty Publications

Background

Dinoflagellates of family Symbiodiniaceae are important to coral reef ecosystems because of their contribution to coral health and growth; however, only a few studies have investigated the function and distribution of Symbiodiniaceae in Indonesia. Understanding the distribution of different kinds of Symbiodiniaceae can improve forecasting of future responses of various coral reef systems to climate change. This study aimed to determine the diversity of Symbiodiniaceae around Lombok using environmental DNA (eDNA).

Methods

Seawater and sediment samples were collected from 18 locations and filtered to obtain fractions of 0.4–12 and >12 µm. After extraction, molecular barcoding polymerase chain reaction was …

Nutrient Capture And Sustainable Yield Maximized By A Gear Modification In Artisanal Fishing Traps, Bryan P. Galligan, Timothy R. Mcclanahan, Austin T. Humphries

Fisheries, Animal and Veterinary Sciences Faculty Publications

Coral reef artisanal fisheries are an important source of nutrition and economic wellbeing for coastal communities, but their management is subject to conflicts and tradeoffs between short-term food security benefits and long-term ecological function. One potential tradeoff is between nutrient capture and fish yields, where targeting small, nutrient-dense species may be more valuable for food security than maximizing fish yields, which is more closely aligned with supporting biodiversity and ecological function. We explored these potential tradeoffs by comparing two similar gears: traditional African basket traps and traps modified with an escape gap. Traps without escape gaps captured a higher frequency …

Organic Farmers Face Persistent Barriers To Adopting Diversification Practices In California’S Central Coast, Liz Carlisle, Kenzo Esquivel, Patrick Baur, Nina F. Ichikawa, Elissa M. Olimpi, Joanna Ory, Hannah Waterhouse, Alastair Iles, Daniel S. Karp, Claire Kremen, Timothy M. Bowles

Fisheries, Animal and Veterinary Sciences Faculty Publications

In the face of myriad environmental challenges associated with industrial agriculture, some farmers and researchers have looked to diversified farming systems as a promising alternative. Despite well-documented ecological benefits, diversification practices remain rare in many regions of the U.S, even amongst organic farmers. Our study focuses on organic farmers in the Central Coast region of California, an area that has played a crucial role in the rise of organic agriculture over the last several decades. Through 20 interviews with farmers who all grow lettuce and 8 interviews with technical assistance providers, we investigate the persistent barriers that growers in this …

Let’S Get R.E.A.L.: Developing A Shared Definition Of Structural Racism Is The First Step Towards Health Equity, Deann Butler

MUSC Theses and Dissertations

Recent events bought to the forefront the need to address structural racism in the US, specifically within the institution of healthcare. Organizations such as the American Public Health Association (APHA, 2021), American Medical Association (AMA) (O’Reilly, 2020), Center for Disease Control and Prevention (CDC) (Walensky, 2021) recognize racism as a fundamental driver of persistent health disparities in minority populations. Additionally, healthcare accreditation organizations such as National Council on Quality Assurance (NCQA, 2022) launched initiatives that strategically work to achieve health equity. More so, organizations across healthcare are creating roles such as Chief Health Equity Officer or Chief Diversity Officer to …

Interviews With Farmers Suggest Negative Direct And Indirect Effects Of The Invasive Green Iguana (Iguana Iguana) On Agriculture In Puerto Rico, Christina N. De Jesús Villanueva, Gabriela P. Massanet Prado, William Gould, Carlos G. Garcia-Quijano

Sociology and Anthropology Faculty Publications

Agricultural communities and crop production are negatively impacted by invasive species, with the effects of pathogenic fungi, parasitic insects and weedy plants being well studied. Mammals and birds are also recognized as impacting crops, but reptiles, such as non-native green iguanas (Iguana iguana), are typically not considered agricultural pests. Research on non-native green iguanas has largely focused on the lizard’s interactions with native species with little attention given to its impact in the agricultural landscape. We conducted semi-structured interviews with farmers from 20 farms in Puerto Rico to explore the effect of the invasive green iguana on the production of …

The Effect Of Covid-19 Infection On The Oral Manifestations, Asmawati, Bahruddin Thalib, Alqarama M. Thalib, Nurlindah Hamrun, Nabilah A. Putri, Eshin Un. Rahman

Journal of Dentomaxillofacial Science

No abstract provided.

Comparison Of Effectiveness Of Normal Saline, Aquades And Mineral Water As An Irrigation Solution In Odontectomy Of Impacted Mandibular Third Molar In University Of Sumatera Utara Hospital, Ahyar Riza, Geby Ak. Bukit

Journal of Dentomaxillofacial Science

No abstract provided.

Minimum Inhibitory Concentration (Mic) And Minimum Bactericidal Concentration Of Beluntas Leaf Ethanol Extract Against Streptococcus Mutans, Elin Septiani, Natallia Pranata, Vinna K. Sugiaman

Journal of Dentomaxillofacial Science

No abstract provided.

The Use Of Teledentistry And Artificial Intelligence (Ai) In Dental And Oral Health Services For The Elderly In The Era Of The Covid-19 Pandemic: A Systematic Review, Bahruddin Thalib, Rifaat Nurrahma, Asmawati, Alqarama M. Thalib, Mohammad Nf. Taufik

Journal of Dentomaxillofacial Science

No abstract provided.

The Effectiveness Of Watermelon Rind Extracts Waste (Citrullus Lanatus L.) In Removing Free Radical In Oral Leukoplakia Patients, Shafira N. Khaera, Ainiyyah F. Zaizafun, Andi N. Anisa, Acing H. Mude

Journal of Dentomaxillofacial Science

No abstract provided.

A Comparative Study Of Online Art History Information Literacy Instruction: A Tale Of Two Platforms, Elsa Loftis

Library Faculty and Staff Publications and Presentations

In a collaborative effort between three departments at Portland State University, investigators designed and created Information Literacy (IL) modules tailored to the needs of Art History students utilizing two delivery platforms. One platform employed adaptive software (in this study, the product is called Realizeit), and the other was a static environment called Pressbooks. Students were randomly divided into cohorts based on these delivery methods. The author compared results of pre and post information literacy assessments and completed an analysis of students’ preliminary bibliographies to measure the success of the IL instruction. But the core investigation was to determine whether the …

Functional Implications Of Dale's Law In Balanced Neuronal Network Dynamics And Decision Making, Victor J. Barranca, Asha Bhuiyan , '23, Max Sundgren , '22, Fangzhou Xing , '22

Mathematics & Statistics Faculty Works

The notion that a neuron transmits the same set of neurotransmitters at all of its post-synaptic connections, typically known as Dale's law, is well supported throughout the majority of the brain and is assumed in almost all theoretical studies investigating the mechanisms for computation in neuronal networks. Dale's law has numerous functional implications in fundamental sensory processing and decision-making tasks, and it plays a key role in the current understanding of the structure-function relationship in the brain. However, since exceptions to Dale's law have been discovered for certain neurons and because other biological systems with complex network structure incorporate individual …

Think-Aloud Interviews: A Tool For Exploring Student Statistical Reasoning, A. Reinhart, C. Evans, Amanda Luby, J. Orellana, M. Meyer, J. Wieczorek, P. Elliott, P. Burckhardt, R. Nugent

Mathematics & Statistics Faculty Works

Think-aloud interviews have been a valuable but underused tool in statistics education research. Think-alouds, in which students narrate their reasoning in real time while solving problems, differ in important ways from other types of cognitive interviews and related education research methods. Beyond the uses already found in the statistics literature—mostly validating the wording of statistical concept inventory questions and studying student misconceptions—we suggest other possible use cases for think-alouds and summarize best-practice guidelines for designing think-aloud interview studies. Using examples from our own experiences studying the local student body for our introductory statistics courses, we illustrate how research goals should …

Maximal And Minimal Weak Solutions For Elliptic Problems With Nonlinearity On The Boundary, S. Bandyopadhyay, M. Chhetri, B. B. Delgado, Nsoki Mavinga, R. Pardo

Mathematics & Statistics Faculty Works

This paper deals with the existence of weak solutions for semilinear elliptic equation with nonlinearity on the boundary. We establish the existence of a maximal and a minimal weak solution between an ordered pair of sub- and supersolution for both monotone and nonmonotone nonlinearities. We use iteration argument when the nonlinearity is monotone. For the nonmonotone case, we utilize the surjectivity of a pseudomonotone and coercive operator, Zorn's lemma and a version of Kato's inequality.

Ba Economics, 2022-23, Arkansas State University - Jonesboro

Bachelor of Arts and others

No abstract provided.

Ba Econ, Pre-Law 2022-23, Arkansas State University - Jonesboro

Bachelor of Arts and others

No abstract provided.

A Simple Algorithm For Generating A New Two Sample Type-Ii Progressive Censoring With Applications, E. M. Shokr, Rashad Mohamed El-Sagheer, Mahmoud Mansour, H. M. Faied, B. S. El-Desouky

Basic Science Engineering

In this article, we introduce a simple algorithm to generating a new type-II progressive censoring scheme for two samples. It is observed that the proposed algorithm can be applied for any continues probability distribution. Moreover, the description model and necessary assumptions are discussed. In addition, the steps of simple generation algorithm along with programming steps are also constructed on real example. The inference of two Weibull Frechet populations are discussed under the proposed algorithm. Both classical and Bayesian inferential approaches of the distribution parameters are discussed. Furthermore, approximate confidence intervals are constructed based on the asymptotic distribution of the maximum …

Incorporating Hemodynamic Cognitive Neuromarkers For Personalized Assistive Communication Technology, Seyyed Bahram Borgheai

Open Access Dissertations

A Brain computer interface (BCI) for communication bypasses standard efferent neural pathways towards peripheral nerves and muscles and directly translates brain activity into symbolic commands to facilitate communication in people with motor impairments. Although a range of access options have been developed, there are still many challenges, particularly for those with severe motor-control limitations. Limitations in availability of access options and the accuracy they provide may lead to patient frustration. Hence, many conventional non-invasive BCIs that rely on eye-gaze control and alternative communicative solutions, such as eye-tracking systems, fail to provide successful and efficient communication in people with severe motor …

Probiotics For Eastern Oyster Hatcheries: Commercial Formulations And Effect On Microbial Communities, Evelyn Takyi

Open Access Dissertations

In the United States of America, oyster production is an important component of the seafood industry in many coastal communities. Oysters provide ecological, economic, and cultural services. Several hatcheries providing eastern oyster, C. virginica, seed to oyster farms face significant losses owing to Vibrio spp. infections causing massive larval mortalities. Probiotics have been proposed as a potential preventive measure to limit the impact of bacterial diseases in shellfish hatcheries. The probiotic bacterium Phaeobacter inhibens S4 has been shown to protect C. virginica larvae from Vibrio coralliilyticus RE22 (RE22) infection. A liquid formulation of this probiotic has been developed for …