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Spatiotemporal Expression Of Regulatory Kinases Directs The Transition From Mitosis To Cellular Morphogenesis In Drosophila, Shuo Yang, Jennifer Mcadow, Yingqiu Du, Jennifer Trigg, Paul H Taghert, Aaron N Johnson

Open Access Publications

Embryogenesis depends on a tightly regulated balance between mitosis, differentiation, and morphogenesis. Understanding how the embryo uses a relatively small number of proteins to transition between growth and morphogenesis is a central question of developmental biology, but the mechanisms controlling mitosis and differentiation are considered to be fundamentally distinct. Here we show the mitotic kinase Polo, which regulates all steps of mitosis in Drosophila, also directs cellular morphogenesis after cell cycle exit. In mitotic cells, the Aurora kinases activate Polo to control a cytoskeletal regulatory module that directs cytokinesis. We show that in the post-mitotic mesoderm, the control of Polo …

Implantable Devices For The Treatment Of Breast Cancer, Mohammad Mohtasim H Pial, Asahi Tomitaka, Nezih Pala, Upal Roy

Health & Biomedical Sciences Faculty Publications

Breast cancer is one of the leading causes of death in the female population worldwide. Standard treatments such as chemotherapy show noticeable results. However, along with killing cancer cells, it causes systemic toxicity and apoptosis of the nearby healthy cells, therefore patients must endure side effects during the treatment process. Implantable drug delivery devices that enhance therapeutic efficacy by allowing localized therapy with programmed or controlled drug release can overcome the shortcomings of conventional treatments. An implantable device can be composed of biopolymer materials, nanocomposite materials, or a combination of both. This review summarizes the recent research and current state-of-the …

Laser Capture Microdissection In The Spatial Analysis Of Epigenetic Modifications In Skin: A Comprehensive Review, Theja Bhamidipati, Mithun Sinha, Chandan K. Sen, Kenhaiya Singh

Student Publications

Each cell in the body contains an intricate regulation for the expression of its relevant DNA. While every cell in a multicellular organism contains identical DNA, each tissue-specific cell expresses a different set of active genes. This organizational property exists in a paradigm that is largely controlled by forces external to the DNA sequence via epigenetic regulation. DNA methylation and chromatin modifications represent some of the classical epigenetic modifications that control gene expression. Complex tissues like skin consist of heterogeneous cell types that are spatially distributed and mixed. Furthermore, each individual skin cell has a unique response to physiological and …

Subanesthetic Ketamine Infusion In Reducing Symptoms Of End-Of-Life Depression: A Case Report, Leanne Groban, Kavita Sharma

Aurora GME

No abstract provided.

Exploring Student Perceptions Of Behavioral, Cognitive, And Emotional Engagement At The Activity Level In General Chemistry, Nicole Naibert, Elizabeth Vaughan, Kylee M. Brevick, Jack Barbera

Chemistry Faculty Publications and Presentations

Although active learning strategies are being incorporated into many higher-education STEM courses, not all students benefit from these activities to the same extent. As these types of activities are designed to engage students in their learning, differences in student engagement may explain some of the differences in learning outcomes. However, before student engagement in active learning activities can be meaningfully measured using a self-report survey, it is important to evaluate if students perceive engagement similarly to the literature definitions on which these measures are based. Therefore, this study sought to explore students’ perceptions of the behavioral, cognitive, and emotional dimensions …

Development And Evaluation Of A Survey To Measure Student Engagement At The Activity Level In General Chemistry, Nicole Naibert, Jack Barbera

Chemistry Faculty Publications and Presentations

Student engagement is an important consideration when incorporating active learning activities into a classroom. To facilitate the large-scale assessment of students’ engagement in activities, a survey measure must first be developed and evaluated. Therefore, the goal of this study was to create a self-report measure of student engagement for use with active learning activities in general chemistry classes. The Activity Engagement Survey (AcES) was modified from an existing survey of engagement of middle and high school science students that contained behavioral, cognitive, emotional, and social engagement items. Multiple rounds of response process interviews and factor analyses were used to modify …

Complexes Of Ghrelin Ghs-R1a, Ghs-R1b, And Dopamine D1 Receptors Localized In The Ventral Tegmental Area As Main Mediators Of The Dopaminergic Effects Of Ghrelin, Gemma Navarro, William Rea, César Quiroz, Estefanía Moreno, Devan Gomez, Cody J. Wenthur, Vicent Casadó, Lorenzo Leggio, Matthew C. Hearing, Sergi Ferré

Biomedical Sciences Faculty Research and Publications

Ghrelin receptor, also known as growth hormone secretagogue receptor (GHS-R1a), is coexpressed with its truncated isoform GHS-R1b, which does not bind ghrelin or signal, but oligomerizes with GHS-R1a, exerting a complex modulatory role that depends on its relative expression. D₁ dopamine receptor (D1R) and D5R constitute the two D₁-like receptor subtypes. Previous studies showed that GHS-R1b also facilitates oligomerization of GHS-R1a with D1R, conferring GHS-R1a distinctive pharmacological properties. Those include a switch in the preferred coupling of GHS-R1a from Gq to Gs and the ability of D1R/D5R agonists and antagonists to counteract GHS-R1a signaling. Activation of ghrelin …

Lymphoma With Tuberculous Granulomas, Jyoti Mohan Lal, Anila Rashid

Department of Pathology and Laboratory Medicine

Chronic granulomatous inflammation is a common finding in lymphoproliferative disorders (LPDs), but it is important to exclude coexisting mycobacterium tuberculosis (MTB) especially in patients from areas of high endemicity. This case emphasizes the relevance of performing MTB culture on bone marrow exhibiting LPD and concomitant granulomas

Considering Natural Baselines When Calculating Livestock Impacts Point To A Negligible Role Of Grass-Fed Livestock Systems In Climate Change, P. Manzano, S. R. White

IGC Proceedings (1977-2023)

The use of baselines is common in a variety of academic disciplines, including environmental science, but they are subjected to relativity depending on the geographical or historical reference considered. Such considerations are illustrated by how invasive species are evaluated or what reference baselines are considered in biodiversity assessments.

The measurement of livestock effects on climate change has, however, disregarded the use of baselines. Current methodology is based exclusively on greenhouse gas emissions by individual animals, without putting them in their ecological context. As a consequence, current analyses of livestock impacts put grass-fed ruminant systems in the spotlight, because of their …

Comparative Soil Organic Carbon Dynamics In Tropical And Subtropical Grassland Ecosystems, N. S. Pasricha, P. K. Ghosh

IGC Proceedings (1977-2023)

Grassland ecosystems play significant role in mitigating the climate change by sequestering atmospheric CO₂. One fifth of the total terrestrial C is stored in the root zone of grasslands as soil organic carbon. However, because of lack of proper management, overgrazing, and conversion to crop lands, these grasslands are becoming a source of CO₂ emissions. It has been observed that in Imperata grasslands of Northeast India, a third of total C captured annually is lost though CO₂ emissions. In the absence of intensified grazing and burning, these grasslands exhibit significantly high capacity to store SOC stocks. …

Climate Change Threats To Semi-Arid Transhumance Grazing Systems: Proposals For Adaptation In Cabo Verde, J. F. Castro, S. Tavares, M. Castro

IGC Proceedings (1977-2023)

Global warming has changed the rainfall regime in the Sahelian region, endangering and widespread poverty and chronic famines in Cape Verde, where rural communities' well-being and food security depend on rainy agriculture. Local responses to rainfall new patterns and scarcity have been livestock reduction with significant revenue losses. Together with dry mist occurrences, these environmental constraints demand to define priority actions to adapt and mitigate climate change's direct impacts. According to fifty household inquiries, this work explains the transhumant grazing practices on a semi-arid plateau in Tarrafal (Santiago, Cabo Verde), prospecting adaptation alternatives for sustainability. We related grazing patterns and …

Wild Red Deer Benefit The Conservation Of European Semi-Natural Open Habitats, F. Riesch, Bettina Tonn, Marcus Meißner, Sven Herzog, Niko Balkenhol, J. Isselstein

IGC Proceedings (1977-2023)

Traditional land use practices have shaped European landscapes for millennia. Agricultural intensification and declining popularity of pastoral farming in the past century have resulted in a tremendous loss of extensively used open landscapes and associated biodiversity. Today, conservation management needs to prevent secondary succession of many open habitats. Large or inaccessible target areas unsuitable for conventional conservation measures might benefit from grazing by wild herbivores, which do not require fencing nor regular welfare monitoring. In a military training area in Germany, we studied the quantitative and qualitative effects of wild red deer in two protected open habitat types (lowland hay …

Protecting Mixed-Status Families: Equal Protection Analysis Of The Dual Social Security Number Requirement, Nena Gallegos

University of Chicago Legal Forum

No abstract provided.

The Need For The Tort Law Necessity Defense In Intellectual Property Law, Yaniv Heled, Ana Santos Rutschman, Liza Vertinsky

University of Chicago Legal Forum

No abstract provided.

Wills Formalities In A Post-Pandemic World: A Research Agenda, Bridget J. Crawford, Kelly Purser, Tina Cockburn

University of Chicago Legal Forum

No abstract provided.

General Adversarial Networks In Tumor-Related Research: A Review And Agenda For Moving Forward, Andrew James Behrens, Cherie Noteboom

SDSU Data Science Symposium

Recent advances in Generative Adversarial Networks (GANs) have led to many new variants and uses of GANs. The latest advancements have allowed researchers and practitioners to apply this technique to tumor-related problems with limited data. One of the trends in this problem domain is to develop different variants of GANs suited explicitly to particular problems. The variants of GANs are numerous but share a common characteristic of expanding the dataset by creating synthetic data from the original dataset. This paper aims to develop a research agenda through a systematic literature review that investigates practitioners' and researchers' emerging issues and current …

Relationships Between Exposure, Knowledge, And Concern In Regards To A Rat Zoonotic Disease As Determined By A Survey Of Chicago Residents., Ashriya Ashik Patel

Undergraduate Research and Engagement Symposium

The threat of increased human and rat population density coupled with the high probability of flooding, based on future climate predictions, could put the Chicago Metropolitan area at risk for a Leptospirosis outbreak. Understanding the relationship between residents' knowledge, concern, and exposure to rat-associated diseases can help monitor and mitigate at-risk behavior that increases the likelihood of spillover events. Using survey data from The Chicago Rat Project, partners with the Lincoln Park Zoo, this study identifies residents' lack of knowledge surrounding Leptospirosis is independent of possible exposure risk or concern regarding rat zoonotic diseases.

Session 2: Datasets For Precision Agriculture Practices, Jiyul Chang

SDSU Data Science Symposium

Precision agriculture practices as a data-based agriculture require many types of data. In data side of view, precision agriculture practices can be explained in three steps which are 1) data acquisition, 2) data processing, and 3) implementation of final decisions. Producers and agronomists collect data from fields and apply the final decisions to farming. Data scientists need to analyze the big data to make a best decision for maximum benefits. However many different types and formats of data cause difficulties of data analysis. This presentation will talk about types and formats of data that are actually using in precision agriculture …

Session 2: A Vision Guidance System On Agricultural Sprayers Reduces Operator Stress, Travis Burgers, Kelly Vanderwerff

SDSU Data Science Symposium

Manually operating an agricultural sprayer is a stressful activity. Operators work an average of 15 hrs/day in peak season [1], navigating 38-cm (15-in) tires in 76-cm (30-in) rows. Guidance systems can relieve operator fatigue [2]. A commercially-available vision guidance system (VSN®, Raven Industries) is available for agricultural vehicles.

Human subject protocols were approved by the IRB. Three experienced male operators drove manually and with VSN in the same field. Each wore an Empatica E4 wristband to measure their electrodermal activity (EDA). Sprayer steering status was recorded from the sprayer guidance system (RS1TM, Raven Industries). EDA data was filtered with a …

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.

2022 Sdsu Data Science Symposium Speaker Information, Department Of Mathematics & Statistics

SDSU Data Science Symposium

This document provides information on the speakers and workshop instructors for the 2022 SDSU Data Science Symposium.

2022 Sdsu Data Science Symposium Presentation Abstracts, Department Of Mathematics & Statistics

SDSU Data Science Symposium

This document contains abstracts for presentations and posters 2022 SDSU Data Science Symposium.

Causal Factors Of Breeding Success And Frequency In Threatened Grassland Birds On The Ingula Nature Reserve, South Africa, R. B. Colyn, C. Pienaar, H. Smit-Robinson, K. Chetty

IGC Proceedings (1977-2023)

The high-altitude grasslands covering the eastern escarpment of South Africa is one of the country’s most valuable habitats for biodiversity, livestock and water production. The habitat hosts several threatened bird species including endangered species such as the Rudd's Lark (Heteromirafra ruddi) and Grey Crowned Crane (Balearica regulorum), and vulnerable species such as the Blue Crane (Grus paradisea), Wattled Crane (Bugeranus carunculatus), Southern Bald Ibis (Geronticus calvus), and Yellow-breasted Pipit (Anthus chloris). Avian research and monitoring have been ongoing within the recently declared Ingula Nature Reserve for more than …

Animal Performance In Signalgrass Monoculture Or In Silvopastoral Systems, I. A. Gomes Da Silva, José C. B. Dubeux Jr., A. C. L. De Melo, Márcio V. Da Cunha, Mércia V. F. Dos Santos, V. X. O. Apolinário, Erinaldo Viana De Freitas, S. B. M. Costa

IGC Proceedings (1977-2023)

Silvopastoral systems (SPS) can increase overall productivity and long-term income due to the simultaneous production of trees, forage, and livestock. This 2-yr study evaluated animal performance and herbage responses in C4-grass monoculture or in SPS in the sub-humid tropical region of Brazil. The experimental design was randomized complete block with three replications. Treatments were: Urochloa decumbens (Stapf.) R. Webster (Signalgrass) + Mimosa caesalpiniifolia Benth (SPS-Mimosa); Signalgrass + Gliricidia sepium (Jacq.) Kunth ex Walp (SPS-Gliricidia); and Signalgrass monoculture (SM). Response variables included herbage and livestock responses. Cattle were managed under continuous stocking with variable stocking rate. There was interaction between treatment …

Legume And Nitrogen Fertilization Affect Animal Performance And Enteric Methane Emission Of Nellore Heifers, B. G. C. Homem, I. B. G. Lima, P. P. Spasiani, José C. B. Dubeux Jr., A. Berndt, D. R. Casagrande

IGC Proceedings (1977-2023)

Methane emission from livestock operation is an important source of greenhouse gas and contributes to global warming. Forage legume secondary compounds may mitigate methane emissions by reducing methanogenic population in the rumen. This study evaluated animal performance and methane emission from beef cattle grazing either a mixed pasture [Brachiaria brizantha cv. Marandu (palisadegrass) and Arachis pintoi (forage peanut) cv. BRS Mandobi] or a palisadegrass monoculture with or without nitrogen (N) fertilisation. A 2.5-yr continuous stocking experiment was carried out in southeast Brazil, on a randomized complete block design with three treatments and four replicates. Two Nellore heifers were used …

People-Environment Trade-Offs In Managing Communal Rangelands Of South Africa, J. E. Bennett, S. Lemke, T. Marandure

IGC Proceedings (1977-2023)

Communal rangelands in South Africa support a range of ecosystem services including water provision, carbon sequestration and livestock production for different stakeholders. Delivering these in a sustainable and socially appropriate manner necessarily requires trade-offs to be made between the different environmental and social outcomes required. We draw on empirical fieldwork and a two-day participatory stakeholder workshop to report on the early stages of a project evaluating these trade-offs in communal rangelands of the uMzimvubu catchment in Eastern Cape Province. Our findings suggest that trade-offs will be necessary at a variety of different levels within this system. For example, a key …

Faculty Senate Meeting, 56th Senate Agenda (2/8/2022), Csusb Faculty Senate

CSUSB Faculty Senate records

No abstract provided.

Harnessing The Four-Dimensional Ecology Education Framework To Redesign An Introductory Ecology Course In A Changing Higher Education Landscape, Nathan Ruhl, Patrick Crumrine, Jennifer Oberle, Courtney Richmond, Shelly Thomas, Sara Wright

School of Earth & Environment Departmental Research

As higher education undergoes rapid and fundamental change, eco-educators need to be prepared to promote the inclusion of the ecological sciences in the biological sciences curriculum of the future. Here, we present an instructional alignment for an introductory ecology course, which is informed by and integrated with the Four-Dimensional Ecology Education (4DEE) Framework. Our instructional alignment was created collaboratively among faculty involved in teaching the course and emphasizes the relevance and utility of the ecological sciences. We believe that this approach positions the ecological sciences for continued success and inclusion in the biological sciences curriculum of tomorrow.

Faculty Senate Meeting, 56th Senate Minutes (2/8/2022), Csusb Faculty Senate

CSUSB Faculty Senate records

No abstract provided.

How To Improve Legal Representation Of Children In America's Child Welfare System, Donald Duquette

Law & Economics Working Papers

From 2009 to 2016 the University of Michigan Law School served as the National Quality Improvement Center on the Representation of Children in the Child Welfare System (QIC-ChildRep). This article provides the final recommendations of this project. These recommendations have not yet been published in the academic literature. This article first summarizes the research findings of the QIC-ChildRep project. Then it sets out QIC-ChildRep recommendations for: 1) Training and supervision of lawyers; 2) State statutes and rules governing lawyers for children; 3) State organizational structure to support child representation; 4) Strategies for recruiting lawyers in this specialty; 5) Caseload size; …