Digital Commons Network^™

Reducing Influenza Virus Transmission: The Potential Value Of Antiviral Treatment, Frederick G Hayden, Jason Asher, Benjamin J Cowling, Aeron C Hurt, Hideyuki Ikematsu, Klaus Kuhlbusch, Annabelle Lemenuel-Diot, Zhanwei Du, Lauren Ancel Meyers, Pedro A Piedra, Takahiro Takazono, Hui-Ling Yen, Arnold S Monto

Faculty, Staff and Students Publications

Prompt antiviral treatment has the potential to reduce influenza virus transmission to close contacts, but rigorous data on the magnitude of treatment effects on transmission are limited. Animal model data indicate that rapid reductions in viral replication after antiviral treatment reduce the risk of transmission. Observational and clinical trial data with oseltamivir and other neuraminidase inhibitors indicate that prompt treatment of household index patients seems to reduce the risk of illness in contacts, although the magnitude of the reported effects has varied widely across studies. In addition, the potential risk of transmitting drug-resistant variants exists with all approved classes of …

Sars-Cov-2 Infection Increases Risk Of Acute Kidney Injury In A Bimodal Age Distribution, Erica C Bjornstad, Gary Cutter, Pramod Guru, Shina Menon, Isabella Aldana, Scott House, Nancy M Tofil, Catherine A St Hill, Yasir Tarabichi, Valerie M Banner-Goodspeed, Amy B Christie, Surapaneni Krishna Mohan, Devang Sanghavi, Jarrod M Mosier, Girish Vadgaonkar, Allan J Walkey, Rahul Kashyap, Vishakha K Kumar, Vikas Bansal, Karen Boman, Mayank Sharma, Marija Bogojevic, Neha Deo, Lynn Retford, Ognjen Gajic, Katja M Gist, Sccm Discovery Virus Investigators Group

Faculty, Staff and Students Publications

BACKGROUND: Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared to children. Our objectives were to evaluate the epidemiology of SARS-CoV2-related AKI across the age spectrum and determine if known risk factors such as illness severity contribute to its pattern.

METHODS: Secondary analysis of ongoing prospective international cohort registry. AKI was defined by KDIGO-creatinine only criteria. Log-linear, logistic and generalized estimating equations assessed odds ratios (OR), risk differences (RD), and 95% confidence intervals (CIs) for AKI and mortality adjusting for sex, pre-existing comorbidities, race/ethnicity, illness severity, …

Potential Of C4 Tropical Grasses To Contribute In Carbon Sequestration, Environmental Security And Livelihood Opportunities Through Increased Fodder Availability, D. R. Malaviya, A. K. Roy, P. Kaushal

IGC Proceedings (1977-2023)

The world grasslands/rangeland ecosystems comprise 26% of earth’s surface and have immense ecological and economic significance. Diversity of grasslands had been a key element for their sustainability. Grasslands in India have existed as natural ecosystems for millions of years. It is a major source of income, employment and livelihood to the rural families. Owing to heavy grazing pressure, coupled with other social/anthropogenic factors, the grazing resources have fast deteriorated. The country has many old and natural grasslands with ethnic and economic value. Comprehensive ecological studies including floristic compositions, dominant species, grazing pressure and the climax/sub-climax stages of ecological succession will …

Linking Ground, Space And Knowledge: The Role Of Weather Forecasting In Pastoralists' Decision-Making, E. L. Mulder, V. C. Wright, S. C. Steele-Dunne, P. H. A. J. M. Van Gelder, H. C. Winsemius

IGC Proceedings (1977-2023)

Changing weather patterns and decreasing land availability continue to challenge the livelihood of the pastoralists in northern Tanzania. The increasing variability of expected rains has complicated livestock management, often jeopardizing household resilience. Drought Early Warning Systems are being set up to contribute to decision-making processes at national and international levels. Nevertheless, due to the large spatial- and temporal resolution of these systems and their high uncertainties, these systems have limited value at a pastoral household level.

Therefore, this paper explores what type of weather and climate information is deemed valuable for pastoral households in Longido District, Tanzania. It is based …

Microbiome Of The Cool Season Forage Grass Timothy (Phleum Pratense L.) And Its Potential Role In Stress Tolerance, Dina Saleh, Suha Jabaji, Philippe Seguin

IGC Proceedings (1977-2023)

The functional attributes of the microbiome associated with timothy for growth promotion properties, antimicrobial and biosurfactant capacities were characterized. A total of 254 culturable bacteria were identified by 16S rRNA sequencing and grouped into 16 taxa that shared high homology of 98–99% with other known sequences. The majority of bacterial isolates exhibited multifunctional growth promotion attributes and plant stress improvement. The selection of competent and compatible strains for application in forage production is dependent on the recognition of root exudates and motility towards the roots, attachment to the root surface, formation of biofilm, penetration, and colonization of internal tissues. We …

Improving The Functionality Of Water Investments In The Drylands: Learning From Kenya’S County Climate Change Fund, C. Bedelian, M. Bonaya, A. Ibrahim, F. Ngarachu, C. Hesse

IGC Proceedings (1977-2023)

Kenya’s County Climate Change Fund (CCCF) is financing public good investments focused on the water sector to increase the resilience of communities to climate change. In the drylands, investments in water are critical for water and food security, yet ensuring the functionality and sustainability of water investments remains an ongoing challenge. This paper assesses the functionality and sustainability of 62 CCCF water investments in five dryland counties (Isiolo, Wajir, Garissa, Kitui and Makueni) in Kenya through a functionality survey and stakeholder workshops. The survey was designed based on a review of studies assessing the functionality of water supply systems. Across …

Language And Betrayal: Posthuman Ethics In Kazuo Ishiguro’S Never Let Me Go, Netty Mattar

CLCWeb: Comparative Literature and Culture

Netty Mattar discusses in her article “Language and Betrayal: Posthuman Ethics in Kazuo Ishiguro’s Never Let Me Go” the complexities of ethical compassion in this biotechnological age. Mattar highlights how genetic technology creates new forms of life that dissolve the line between ‘human’ and ‘technology.’ In spite of this, contemporary ethical discussions do not take into account changing conceptions of human subjectivity and instead reinstate older assumptions about what ‘human’ is. Mattar argues that speculative fiction (SF), as a self-conscious play on signs and signification, can draw attention to how ethical responses are determined by the language we use. …

The Symbolism Of Clothing: The Naked Truth About Jacques Lacan, Peter D. Mathews

CLCWeb: Comparative Literature and Culture

In the work of Jacques Lacan there exists an extended metaphor of clothing, whereby the ‘naked’ truth is always ‘clothed’ in deception. For Lacan, clothing functions at the intersection of the symbolic and the imaginary, with outward appearance shaping what we imagine to be underneath in order to determine the landscape of symbolic desire. Joan Copjec considers the political implications of this metaphor, arguing that utilitarianism, in particular, divides desire into a false dichotomy of rational, naked desire, and the ornamental clothing of irrationality, a mindset woven into both capitalism and French colonialism. The article then examines two examples from …

Tituba, “Dark Eve” In The Origins Of The American Myth: The Subject Of History And Writing About Salem, Junghyun Hwang

CLCWeb: Comparative Literature and Culture

Recasting the Salem witchcraft trials in light of Walter Benjamin’s theses on historiography, this paper revisits the question of history by examining ways in which Tituba is dis/con-figured as the subject of American history in Arthur Miller’s The Crucible and Maryse Condé’s I, Tituba, Black Witch of Salem. Both stories of persecution revolve around the figure of Tituba, a slave from the Caribbean to whom the beginning of the witch trials is attributed, as the nodal point of different modes of representing the Salem history. The telos in Miller’s drama coincides with the subject-formation of Proctor as the legitimate …

Beyond Victimhood: Female Agency In Nigerian Civil War Novels, Enajite E. Ojaruega

CLCWeb: Comparative Literature and Culture

Enajite E. Ojaruega discusses in her “Beyond Victimhood: Female Agency in Nigerian Civil War Novels” the agential roles women played during the Nigeria-Biafra war as reflected in selected fictional narratives. Female characters are generally impacted negatively by their individual and collective war-time experiences. However, there is another important aspect of women's war-time experiences that has largely been underplayed in most historical or literary accounts on war. Female agency recognizes this gender’s participatory roles during the conflict as they reconstruct their subjectivity in more beneficial ways in the unfolding circumstances of war. Women are depicted as being able to explore their …

Size Estimates Of The Extinct Marine Snake Pterosphenus Schucherti From Eocene-Aged Sediments Of Central Georgia, Colin J. Calvert, Alfred J. Mead, Dennis Parmley

Georgia Journal of Science

Fossil snakes are most often identified from isolated vertebrae, complicating estimations of total body lengths of extinct taxa. Here we estimate the range of total body length of the late Eocene North American palaeophiid marine snake Pterosphenus schucherti based on 29 recently collected fossil vertebrae from Wilkinson County, Georgia, USA. Previous research suggests that the palaeophiids are most closely related to modern boids. Total body length estimates here are based on family-specific regressions of centrum length versus known total body length in extant members of Boidae, Pythonidae, and Colubridae. The high correlation coefficients for the family specific regressions supports previous …

University Curriculum Committee Meeting Minutes - February 10, 2022, University Curriculum Committee

University Curriculum Committee Meeting Materials

Minutes for the Governors State University Curriculum Committee Meeting held February 10, 2022.

Strange Fruit, Office Of Arts + Cultural Programming, Peak Performances At Montclair State University

2021-2022 Join Us in Engaging with the Imaginations of Unparalleled Visionaries

Strange Fruit draws its title from the 1937 poem and song of the same name by Abel Meeropol and made famous by the great jazz singer Billie Holiday—which metaphorically addresses lynching as a tool of racial terrorism during the Jim Crow Era. For this dance/theater work, the facts of lynching act as springboards into a highly personal interior space and state of mind. Abstract yet grounded in a brutal reality, Strange Fruit tracks choreographer Donald Byrd’s feelings as a response to lynching and plays out as a series of dance/theater vignettes.

Applications Of Data Science In Biological Science Dsp 569, Harrison Dekker

Collection Development Reports and Documents

No abstract provided.

University Curriculum Committee Meeting Minutes - February 10, 2022, University Curriculum Committee

Faculty Senate Minutes

Minutes for the Governors State University Curriculum Committee Meeting held February 10, 2022.

Long-Read Sequencing Of The Zebrafish Genome Reorganizes Genomic Architecture, Yelena Chernyavskaya, Xiaofei Zhang, Jinze Liu, Jessica S. Blackburn

Molecular and Cellular Biochemistry Faculty Publications

BACKGROUND: Nanopore sequencing technology has revolutionized the field of genome biology with its ability to generate extra-long reads that can resolve regions of the genome that were previously inaccessible to short-read sequencing platforms. Over 50% of the zebrafish genome consists of difficult to map, highly repetitive, low complexity elements that pose inherent problems for short-read sequencers and assemblers.

RESULTS: We used long-read nanopore sequencing to generate a de novo assembly of the zebrafish genome and compared our assembly to the current reference genome, GRCz11. The new assembly identified 1697 novel insertions and deletions over one kilobase in length and placed …

Insecticide Resistance In Australian Spodoptera Frugiperda (J.E. Smith) And Development Of Testing Procedures For Resistance Surveillance, Lisa Bird, Melina M. Miles, Adam Quade, Helen Spafford

Biosecurity Research Articles

Spodoptera frugiperda (J.E. Smith) is a highly invasive noctuid pest first reported in northern Australia during early 2020. To document current status of resistance in S. frugiperda in Australia, insecticide toxicity was tested in field populations collected during the first year of establishment, between March 2020 and March 2021. Dose-response was measured by larval bioassay in 11 populations of S. frugiperda and a susceptible laboratory strain of Helicoverpa armigera. Emamectin benzoate was the most efficacious insecticide (LC50 0.023μg/ml) followed by chlorantraniliprole (LC50 0.055μg/ml), spinetoram (LC50 0.098μg/ml), spinosad (LC50 0.526μg/ml), and methoxyfenozide (1.413μg/ml). Indoxacarb was the least toxic …

Cilia Proteins Are Biomarkers Of Altered Flow In The Vasculature, Ankan Gupta, Karthikeyan Thirugnanam, Madhan Thamilarasan, Ashraf M. Mohieldin, Hadeel T. Zedan, Shubhangi Prabhudesai, Meghan R. Griffin, Andrew D. Spearman, Amy Pan, Sean P. Palecek, Huseyin C. Yalcin, Surya M. Nauli, Kevin R. Rarick, Rahima Zennadi, Ramani Ramchandran

Pharmacy Faculty Articles and Research

Cilia, microtubule-based organelles that project from the apical luminal surface of endothelial cells (ECs), are widely regarded as low-flow sensors. Previous reports suggest that upon high shear stress, cilia on the EC surface are lost, and more recent evidence suggests that deciliation—the physical removal of cilia from the cell surface—is a predominant mechanism for cilia loss in mammalian cells. Thus, we hypothesized that EC deciliation facilitated by changes in shear stress would manifest in increased abundance of cilia-related proteins in circulation. To test this hypothesis, we performed shear stress experiments that mimicked flow conditions from low to high shear stress …

Sex Differences In Desiccation Tolerance Varies By Colony In The Mesic Liverwort Plagiochila Porelloides, Juliana Da C. Silva-E-Costa, Andrea P. Luizi-Ponzo, David Nicholas Mcletchie

Biology Faculty Publications

Water scarcity, a common stress factor, negatively impacts plant performance. Strategies to cope with it, such as desiccation tolerance, are becoming increasingly important to investigate. However, phenomena, such as intraspecific variation in stress responses have not received much attention. Knowledge of this variability and the environmental drivers can be leveraged to further investigate the mechanisms of desiccation tolerance. Here we tested for variation in desiccation tolerance in Plagiochila porelloides among colonies and sexes within the same riparian zone. Field-collected dehardened plants were subjected to a desiccation event, under controlled conditions and then rehydrated. Plant water status, photosynthetic rates, net carbon …

Hydrological Seasonality And Nutrient Stoichiometry Control Dissolved Organic Matter Characterization In A Headwater Stream, Siyue Li, Jiachen Luo, Y. Jun Xu, Liuqing Zhang, Chen Ye

Faculty Publications

Dissolved organic matter (DOM) is a diverse and highly complex mixture of organic macromolecules, and thus plays a central role in aquatic ecosystems. However, responses of components and sources of DOM to hydrological processes and trophic levels (nutrient stoichiometric ratios) are poorly understood, particularly in monsoonal headwater streams of Asia that are vulnerable to catchment physical characteristics. In this study, the excitation - emission matrix florescence spectroscopy coupled with parallel factor analysis (EEM-PARAFAC) was used to explore the DOM characters in a headwater stream, where seasonal rainfalls and nutrient levels vary largely. The EEM-PARAFAC modelling identified one autochthonous protein-like fluorescence …

Optimizing Graminoid Composition In Cost-Effective Seed Mixes For Prairie Strips, Justin Meissen

Tallgrass Prairie Publications and Reports

In order to reduce nutrient loss and increase other ecological benefits, there is growing interest in integrating reconstructed tallgrass prairie stands within and around crop fields. The most recent Farm Bill creates a new conservation practice (CP-43, Prairie Strips) to encourage prairie vegetation in and around farmed fields for the Conservation Reserve Program (CRP). Because this practice is flexible and easy to integrate into conventionally farmed fields, Prairie Strips have proven very popular, and nearly 15,000 acres have been enrolled in less than 2 years (Farm Service Agency 2021).

To optimize the potential value of this popular nutrient reduction practice, …

Second Heart Field–Derived Cells Contribute To Angiotensin Ii–Mediated Ascending Aortopathies, Hisashi Sawada, Yuriko Katsumata, Hideyuki Higashi, Chen Zhang, Yanming Li, Stephanie Morgan, Lang H. Lee, Sasha A. Singh, Jeff Z. Chen, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Debra L. Rateri, Ying H. Shen, Scott A. Lemaire, Masanori Aikawa, Mark W. Majesky, Hong S. Lu, Alan Daugherty

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: The ascending aorta is a common location for aneurysm and dissection. This aortic region is populated by a mosaic of medial and adventitial cells that are embryonically derived from either the second heart field (SHF) or the cardiac neural crest. SHF-derived cells populate areas that coincide with the spatial specificity of thoracic aortopathies. The purpose of this study was to determine whether and how SHF-derived cells contribute to ascending aortopathies.

METHODS: Ascending aortic pathologies were examined in patients with sporadic thoracic aortopathies and angiotensin II (AngII)–infused mice. Ascending aortas without overt pathology from AngII-infused mice were subjected …

Curriculum Minutes 02/10/2022, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.

Antibody Response To Sars-Cov-2 Infection And Vaccination In Covid-19-Naive And Experienced Individuals, Susan L. Uprichard, Amornrat O'Brien, Monika Evdokimova, Cynthia L. Rowe, Cara Joyce, Matthew Hackbart, Yazmin Edith Cruz Pulido, Courtney A. Cohen, Michelle L. Rock, John M. Dye, Paul Kuehnert, Keersten M. Ricks, Marybeth Casper, Lori Linhart, Katrina Anderson, Laura Kirk, Jack A. Maggiore, Andrew S. Herbert, Nina M. Clark, Gail E. Reid, Susan C. Baker

Biostatistics Collaborative Core: Faculty Publications and Other Works

Understanding the magnitude of responses to vaccination during the ongoing SARS-CoV-2 pandemic is essential for ultimate mitigation of the disease. Here, we describe a cohort of 102 subjects (70 COVID-19-naïve, 32 COVID-19-experienced) who received two doses of one of the mRNA vaccines (BNT162b2 (Pfizer–BioNTech) and mRNA-1273 (Moderna)). We document that a single exposure to antigen via infection or vaccination induces a variable antibody response which is affected by age, gender, race, and co-morbidities. In response to a second antigen dose, both COVID-19-naïve and experienced subjects exhibited elevated levels of anti-spike and SARS-CoV-2 neutralizing activity; however, COVID-19-experienced individuals achieved higher antibody …

Faculty Senate Chronicle February 10, 2022, Heather M. Loughney

The University of Akron Faculty Senate Chronicle

Minutes for the regular meeting of The University of Akron Faculty Senate on February 10, 2022

Detection Of Methicillin-Resistant Staphylococcus Aureus Infections Using Molecular Methods, Fred C. Tenover, Isabella A. Tickler

Biology Faculty Publications

The application of molecular detection methods for bacterial pathogens has dramatically improved the outcomes of septic patients, including those with methicillin-resistant Staphylococcus aureus (MRSA) infections. Molecular methods can be applied to a variety of clinical specimens including nasal swabs, growth in blood culture bottles, and wounds. While data show that the overall accuracy of molecular tests for MRSA is high, results can be confounded by the presence of multiple staphylococcal species in a specimen, insertions and deletions of DNA in and around the Staphylococcal Cassette Chromosome mec (SCCmec) element, and point mutations in mecA. Herein, we explore the complexities of …

Post-Termination Effects Of Cover Crop Monocultures And Mixtures On Soil Inorganic Nitrogen And Microbial Communities On Two Organic Farms In Illinois, Eleanor E. Lucadamo, Ashley A. Holmes, Samuel E. Wortman, Anthony C. Yannarell

Department of Agronomy and Horticulture: Faculty Publications

Cover crops can continue to affect agricultural systems even after they have been terminated by influencing nitrogen dynamics and by altering soil microbial communities. These post-termination effects can influence soil fertility, weed pressure, and the dynamics of potential plant pathogens in the narrow window of time between cover crop termination and cash crop emergence. We evaluated the post-termination effects of 12 different spring-sown cover crop mixtures and monocultures on soil nitrogen and microbial communities on two different organic farms in Central Illinois (on Lawson silt loam soil) and Northern Illinois (on Virgil silt loam soil). In comparison to control plots …

Palaeoecological Data Indicates Land-Use Changes Across Europe Linked To Spatial Heterogeneity In Mortality During The Black Death Pandemic, A. Izdebski, P. Guzowski, R. Poniat, L. Masci, J. Palli, C. Vignola, M. Bauch, C. Cocozza, R. Fernandes, F. C. Ljungqvist, T. Newfield, A. Seim, D. Abel-Schaad, F. Alba-Sánchez, L. Björkman, A. Brauer, A. Brown, S. Czerwiński, A. Ejarque, M. Fiłoc, A. Florenzano, E. D. Fredh, R. Fyfe, N. Jasiunas, P. Kołaczek, K. Kouli, R. Kozáková, M. Kupryjanowicz, P. Lagerås, P. Lagerås, M. Lindbladh, J. A. López-Sáez, R. Luelmo-Lautenschlaeger, K. Marcisz, F. Mazier, S. Mensing, A. M. Mercuri, K. Milecka, Y. Miras, A. M. Noryśkiewicz, E. Novenko, M. Obremska, S. Panajiotidis, M. L. Papadopoulou, A. Pędziszewska, S. Pérez-Díaz, G. Piovesan, A. Pluskowski, P. Pokorny, A. Poska, T. Reitalu, M. Rösch, L. Sadori, Ferreira C Sá, D. Sebag, M. Słowiński, M. Stančikaitė, N. Stivrins, I. Tunno, S. Veski, A. Wacnik, A. Masi

School of Geography, Earth and Environmental Sciences

AbstractThe Black Death (1347–1352 ce) is the most renowned pandemic in human history, believed by many to have killed half of Europe’s population. However, despite advances in ancient DNA research that conclusively identified the pandemic’s causative agent (bacterium Yersinia pestis), our knowledge of the Black Death remains limited, based primarily on qualitative remarks in medieval written sources available for some areas of Western Europe. Here, we remedy this situation by applying a pioneering new approach, ‘big data palaeoecology’, which, starting from palynological data, evaluates the scale of the Black Death’s mortality on a regional scale across Europe. We collected pollen …

The Cowl - V. 86 N. 12 - Feb 10, 2022

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 12 - February 10, 2022. 28 pages.

Post-Termination Effects Of Cover Crop Monocultures And Mixtures On Soil Inorganic Nitrogen And Microbial Communities On Two Organic Farms In Illinois, Eleanor E. Lucadamo, Ashley A. Holmes, Samuel E. Wortman, Anthony C. Yannarell

Department of Agronomy and Horticulture: Faculty Publications

Cover crops can continue to affect agricultural systems even after they have been terminated by influencing nitrogen dynamics and by altering soil microbial communities. These post-termination effects can influence soil fertility, weed pressure, and the dynamics of potential plant pathogens in the narrow window of time between cover crop termination and cash crop emergence. We evaluated the post-termination effects of 12 different spring-sown cover crop mixtures and monocultures on soil nitrogen and microbial communities on two different organic farms in Central Illinois (on Lawson silt loam soil) and Northern Illinois (on Virgil silt loam soil). In comparison to control plots …