Digital Commons Network^™

The Effects Of Cannabis Use On Physical Activity, Nitya Chiru, Brionna L. Smith, Karen L. Cropsey, Elizabeth K. Lee

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Improving Cannabis Sativa's Phytoremediation Capabilities Of Forever Chemicals Through Microbial Inoculations, Tyler S. Jolin

All NMU Master's Theses

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that pose ecological and human health risks due to their resistance to degradation and potential for bioaccumulation. Phytoremediation has emerged as a potential strategy for mitigating PFAS contamination, and plant-microbe interactions may influence contaminant uptake and transport within plant systems. These studies investigated microbial inoculation methods and examined whether Bacillus subtilis could influence the uptake and distribution of perfluorooctane sulfonate (PFOS) in hydroponically grown hemp (Cannabis sativa L.). Plant height and stem diameter growth rates and biomass accumulation were compared across treatments with and without PFOS exposure and microbial inoculation. PFOS …

News From Hope College, Volume 57.3: Spring 2026, Hope College

News from Hope College

No abstract provided.

Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang

Chemistry Faculty Research & Creative Works

Cataract is a leading cause of vision impairment worldwide and are primarily caused by oxidative stress that damages and aggregates lens proteins, leading to lens opacification. However, the eye's anatomical barriers limit the penetration and bioavailability of antioxidant therapies. To address this challenge, a dendrimer-based nanogel with a built-in reactive oxygen species (ROS)-scavenging capability developed by us was employed to deliver the antioxidant N-acetylcysteine (NAC) to the lens. NAC was loaded into a generation-5 PEGylated poly(amidoamine) dendrimer (G5-PEG-TK, termed the GPT) nanogel. The resulting NAC-GPT was characterized for its ROS-scavenging activity, bioavailability, and corneal permeability. The efficacy of NAC-GPT was …

Altered Pruning In A Generative Neural Network, Sara Momen

Honors Theses

This study examines whether altered pruning in a generative neural network leads to more restricted or repetitive outputs, using Autism Spectrum Disorder (ASD) as a cautious computational analogy rather than as a biological equivalence. A compact denoising diffusion probabilistic model (DDPM) with a U-Net backbone was trained on CIFAR-10, and pruning percentage was treated as the primary structural variable. Instead of relying on a single assumed baseline, the final implemented study evaluated 0%, 10%, 15%, 20%, 35%, and 50% pruning under controlled conditions: the same dataset, the same epoch budget, the same random seed, and 1,000 generated samples per condition. …

Endocrine Roles Of Vitamin D In Female Reproduction: Mechanisms And Clinical Implications, Azza Alsuwaidi, Fatme Alanouti, Dimitrios Papandreou

All Works

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This review of studies from 2013-2025 found consistent associations between low vitamin D status and various disorders in women of childbearing age. In Premenstrual Syndrome (PMS), deficiency correlates with higher symptom severity, and evidence shows that supplementation significantly reduces total PMS scores, particularly improving mood-related domains. For uterine pathologies such as fibroids, endometriosis, and adenomyosis, low vitamin D status is linked to increased risk and severity. Repletion trials suggest antifibrotic and …

Monitoring Terrestrial Ecosystem Productivity Using Hyperspectral Satellite Data, Serge Tuyambaze

School of Natural Resources: Dissertations, Theses, and Student Research

Accurate estimation of terrestrial Gross Primary Productivity (GPP) is critical for quantifying global carbon sequestration and understanding the terrestrial carbon cycle. While eddy covariance (EC) towers provide standard flux measurements, upscaling these measurements to continuous global coverage remains challenging due to the sparse distribution of flux towers and their small footprints. Remote sensing (RS), especially coupled with eddy covariance data, has been used to estimate GPP at the global scale. Different RS derived productivity models have been developed, including vegetation indices, light use efficiency (LUE) models, solar-induced fluorescence (SIF), dynamic global vegetation models (DGVM), and machine learning. One widely adapted …

Birdshot Chorioretinopathy: A Review Of Diagnosis And Treatment, Jill Gottehrer Od, Steven Follansbee Od

Optometric Clinical Practice

Background: Birdshot chorioretinopathy is a rare, bilateral chronic uveitis resulting in choroidal and retinal inflammation in the form of vasculitis, papillitis, and/or macular edema. For an accurate diagnosis, a thorough patient history, fundoscopic exam, and appropriate ancillary testing are necessary.

Case Report: A 49-year-old male presented to the eye clinic due to vitreous floaters in both eyes that had worsened over the last year. The patient was new to the clinic with no prior history of eye examinations. At presentation, a mild vitritis was noted along with small, multiple white dots in the posterior pole of both eyes. Ancillary testing, …

Hlt 101 Introduction To Public Health, Elyse Gruttadauria

Open Educational Resources

The syllabus, created by Professor Elyse Gruttadauria as part of the CUNY OER Initiatives for HLT 101 contains a course description, course objectives, course readings divided by week and a link to four OER textbooks.

Exposome In Relation To Psychopathology And Physical Pain In Adolescence, Alexsia E. Newman

Honors Scholar Theses

The overall well-being of adolescents is dependent on a variety of factors during development, including both mental and physical health. Mental health, or psychopathology, which includes internalizing and externalizing problems, represents a common and persistent concern among youth. Physical pain is another important aspect of adolescent well-being. Although prior research has examined associations between mental health and pain, less is known about how these relationships unfold over time, and few studies have considered the role of multilevel environmental factors. This honors thesis explores the predictability and bidirectionality of mental health and chronic pain in developing adolescents, and tests associations of …

The Cowl - V. 89 N. 17 - April 1, 2026

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 17 - April 1, 2026. 20 pages.

Audit Report For Self-Help Chatbot, Keith Porcaro, Carmela D'Antuono, Wilson Jeter, Bridgett Kohno, Alexander Mcelya, Nikolas Osoria, Melinda Xiaong, Demi Yang

Duke Center on Law & Technology

This audit report investigates a self-help chatbot designed for Nevada litigants with family law or probate cases. The audit was conducted in Spring 2026 as part of Duke’s AI Audits and Access to Justice practicum, in partnership with the Nevada Administrative Office of the Courts.

Dissecting The Genetic Basis Of Relevant Fruit Quality Traits In Interspecific Grapevines (Vitis Spp.), Venkateswara Rao Kadium, Ramesh Pilli, Andrej Svyentek, Zhuoyu Wang, John Stenger, Rajasekharreddy Bhoomireddy, Collin Auwarter, Xuehui Li, Harlene Hatterman-Valenti

APC Fund Awardees

Understanding the genetic control of fruit composition traits in interspecific grapevines (Vitis spp.) is crucial when breeding new cultivars with desirable fruit chemistry. To address this, a genome-wide association study (GWAS) was conducted using 587 genotypes derived from three elite selections. This study spanned 3 years (2020–2022) and with phenotyping conducted at three different timepoints within each season for a total of nine phenotyping events focused on nine fruit traits. Several strong and stable quantitative trait locus (QTL) associations were identified on chromosomes 6, 16, and 17 across multiple phenotyping events for most sugar- and acid-related traits. Notably, putative sugar …

Interventions For Reducing Barriers To Future Employment Success In First-Generation College Students., Kellie M. Burke

Doctor of Social Work Capstone Projects

First-generation college students (FGCS) comprise a significant and diverse segment of the U.S. undergraduate population, yet they remain disproportionately vulnerable to barriers that impede both academic achievement and career advancement. These challenges, rooted in intersecting factors (e.g., race & gender), are amplified by institutional structures that inadequately address the realities faced by FGCS. Despite the proliferation of career development programs, internship participation, and subsequent employment, among FGCS remains notably low, revealing persistent gaps in support, access, and program efficacy.

This qualitative study evaluates the Rising Leaders Program, an agency-driven intervention designed to promote career readiness for FGCS at Kentucky universities …

Alternative Anticoagulation Strategies For Heparin-Intolerant Patients Undergoing Cardiopulmonary Bypass: A Scoping Review Of Patient Outcomes, Zachary Nelson

Student Works

Background/Introduction: Heparin intolerance, most notably heparin-induced thrombocytopenia (HIT), presents a major clinical challenge during cardiopulmonary bypass (CPB), where systemic anticoagulation is essential for safe circulation through the extracorporeal circuit. While several alternative anticoagulants have been described, there is limited consensus regarding their safety, dosing, and outcomes. The objective of this study was to map existing evidence describing alternative anticoagulation strategies for heparin-intolerant adult patients undergoing CPB and to summarize reported patient outcomes, dosing strategies, and intraoperative management considerations.

Methodology: This scoping review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) …

Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley

Markey Cancer Center Faculty Publications

Background: Almost all correlation measures currently available are unable to directly handle missing values. Typically, missing values are either ignored completely by removing them or are imputed and used in the calculation of the correlation coefficient. In either case, the correlation value will be impacted based on the perspective that the missing data represents no useful information. However, missing values occur in real datasets for a variety of reasons. In metabolomics datasets a major reason for missing values is that a specific measurable phenomenon falls below the detection limits of the analytical instrumentation (left-censored values). These missing data are not …

Mapping The Polar Neuro-Interactome Of Garcinia Mangostana Against The Ad-Pd-Als Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, Jitbanjong Tangpong

Markey Cancer Center Faculty Publications

Background/Objectives: Neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Amyotrophic lateral sclerosis (ALS) share common molecular pathways, including neuroinflammation and oxidative stress, which complicate the effectiveness of single-target treatments. Garcinia mangostana L. (mangosteen) has shown neuroprotective properties, but previous studies focused on lipophilic xanthones, which have poor bioavailability and uncertain blood–brain barrier permeability. Methods: In the current study, polar metabolites from G. mangostana peel aqueous extract (GMPE) were assessed for potential multi-target interactions via UHPLC-QTOF-MS-based metabolomics, systems pharmacology, and molecular docking analysis. Further, in silico ADMET screening and network-based analyses assessed for overlap between GMPE compounds and genes associated with neurodegeneration (AD, …

Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath

Markey Cancer Center Faculty Publications

Age-related cellular changes negatively impact CD4⁺ T cell function. Our prior work showed that mitochondrial complex II (succinate dehydrogenase [SDH]) expression was upregulated in T cells from older (O) adults (60–80 years old). T cells from older adults also produced higher amounts of cytokines generally considered proinflammatory, such as Th17 cytokines IL-17A/F and IL-21, and the Th-17-supportive cytokine IL-6, compared to T cells from younger (Y) adults (25–40 years old). The objective of our study is to evaluate whether hyperactivation of SDH is required for the induction of proinflammatory cytokines and the mechanistic link between SDH and Th17 cytokine …

Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann

Markey Cancer Center Faculty Publications

Chronic ethanol (EtOH) consumption is a major contributor to multi-organ dysfunction, yet its systemic effects remain incompletely understood. To address this, we utilized a physiologically relevant long-term mouse model, administering 20% EtOH in drinking water for 60 weeks, to investigate the integrated consequences of chronic exposure. EtOH-consuming mice (0.4–0.5 mL/day) exhibited > 30% reductions in chow and fluid intake, resulting in a 12% decrease in total caloric intake compared to controls (p < 0.001). Body mass remained similar until Week 52, after which EtOH-treated mice had lower body mass due to reductions in both lean and fat mass (p ≤ 0.004). Functional assessments revealed impaired treadmill endurance (−17%) and grip strength (−11%) (p ≤ 0.037), while motor coordination remained unaffected (p = 0.203). Chronic EtOH exposure significantly altered gut microbiota composition, reducing Lactobacillus and enriching Faecalibaculum, Clostridium, and Bifidobacterium at the genus level. These changes were accompanied by marked depletion of short-chain fatty acids (p ≤ 0.05). Indirect markers of gut permeability (serum LPS & zonulin) and liver injury (serum ALT & AST, hepatic amyloid content) were elevated, alongside increased total cholesterol and > 62% upregulation of hepatic TNFα, IL-6 & serum amyloid A (p ≤ 0.046). EtOH also induced dyslipidemia and glucose intolerance (p ≤ 0.041), although transcriptomic changes in white adipose …

Embodied Horror: Women And Medical Authority In Video Games, Jocilynn Denise Colombo

Comparative Literature M.A. Essays

Through a critical analysis of interactive horror, this paper argues that video games can function as ethical diagnostic narratives that uniquely expose systemic failures surrounding women’s bodies and medical authority. Focusing on Silent Hill 3 (2003) and Alice: Madness Returns (2011), I examine how these games render harm legible through player participation. By requiring players to move characters through hostile environments and make decisions within systems that simultaneously grant and restrict control, these games foster identification and complicity by positioning players directly within the structures they critique.

While feminist horror scholarship—notably from Julia Kristeva and Barbara Creed—has explored societal anxieties …

The Transparent Crypt: Temporal Stratification, Materiality, And The Affective Archive In Jenny Erpenbeck’S "Kairos", Mallory Wooldridge

Comparative Literature M.A. Essays

For Germany, the process of reckoning with the past is not a new one. Termed Vergangenheitsbewältigung in the post-war period and envisioned as a project extending beyond the academy into public consciousness, “dealing with the past” was first envisioned in response to the Nazi regime and its horrors. While already a disjointed project in the Nazi context, the question of how reunified Germany reckons with the former German Democratic Republic’s past remains unresolved.

In her 2021 novel Kairos, Jenny Erpenbeck proposes a different model of historical consciousness. Drawing on Theodor Adorno’s post-war theory of working through the past ( …

World Health Organization Classification Of Tumours Of The Breast 6th Edition 2026, Cecily Quinn, Puay Tan, Kimberly Allison, Edi Brogi, Sunil Lakhani, Stuart Schnitt, Stephen Fox, Shabnam Jaffer, Aysegul Sahin, Shahin Sayed

Pathology, East Africa

The 6th edition of the WHO Classification of Breast Tumours introduces both major and minor changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimens necessitating modifications to pathology reporting and tumour biomarker categorisation. This review summarises the main changes that strive towards a classification of global relevance. In invasive carcinoma, predictive factors increasingly inform modern breast cancer treatment. The 6th edition provides an update on HER2 reporting categories following the DESTINY-Breast 04 and 06 trials. Terminologies used to classify invasive tumours are clarified, with the …

Technostress, Worker Wellbeing, And Ethics: An Integrative Review, Mackenzie Moreno

Theses and Dissertations from DePaul University

Rapid advances in workplace technologies have led to increasing concerns about technostress and its implications for worker health and wellbeing. While the technostress literature has at times addressed psychological and physiological wellbeing outcomes, these outcomes have not been examined consistently, and explicit integration of ethics is largely absent. This integrative review addresses these gaps by synthesizing empirical findings on how technostress impacts worker health and wellbeing, and by examining the extent to which ethical considerations are integrated into the extant literature. Drawing on these findings, the review proposes a theoretical model of technostress mechanisms. Finally, it summarizes organizational recommendations for …

Exploring The Roles Of Grit And Health Anxiety In The Relationship Between Discrimination And Pain-Coping Among Adolescents And Young Adults, Giselle Mcpherson Isbell

Theses and Dissertations from DePaul University

Chronic pain is a complex and highly prevalent concern that can significantly disrupt functioning during adolescence and emerging adulthood. Pain during this developmental period may interfere with academic engagement, social relationships, emotional functioning, and the transition toward independence. Psychosocial stressors such as discrimination and heightened health anxiety may negatively influence pain experiences and coping, whereas protective psychological characteristics such as grit may buffer these effects. The present study examined the relationships between discrimination, health anxiety, grit, pain outcomes, and coping strategies in emerging adults with chronic pain. Participants completed self-report measures assessing discrimination, health anxiety, grit, pain intensity and frequency, …

Snapshot Usa 2024: Year 6 Of The Coordinated National Camera Trap Survey Of The United States, Brigit Rooney, Roland Kays, Michael V. Cove, Alex Jensen, Daniel J. Herrera, Camilla Price, Phuong-Thao Nguyen-Nu, Katrina Adamczyk, Peter D. Alexander, Drew R. Davis

School of Integrative Biological & Chemical Sciences Faculty Publications

Motivation: SNAPSHOT USA is an annual, multi-contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of species interactions on daily activity patterns.

Main Types of Variables Contained: SNAPSHOT USA 2024 contains 377,427 records of camera trap image sequence data and 3127 records of camera trap deployment metadata.

Spatial Location …

Connecting Children To Urban Environments Through Picture Books, Sophie Taylor

School of Education and Leadership Student Capstone Projects

More children than ever before live in urban locations, and many do not see their city streets and natural environments represented in picture books. In the midst of a climate crisis, educators and parents may be seeking environmental books and activities that seek to connect children to their natural communities. The purpose of this capstone project was to explore the importance of picture books in connecting children with their environment through the creation of an urban-based children’s book with embedded environmental terminology and concepts, as well as associated activities. A review of relevant literature uncovered five central themes: illustrated books’ …

Rooted In Wonder: Cultivating A Connection To The Environment Through Nature-Based Learning In Central Mexico, Mikaela Tennis

School of Education and Leadership Student Capstone Projects

Children are spending less time outdoors and feeling increasingly disconnected from the natural world. This reduced exposure and lack of interaction limits opportunities to form early connections with nature, which have lasting benefits into adulthood. Nature-based learning approaches have been proven to increase a sense of nature connectedness, which in turn strengthens one’s environmental attitudes and behaviors while supporting mental health and well-being. To address limited access to nature-based learning experiences in Central Mexico, this capstone draws from research on nature connectedness, nature-based learning, and nature center design to answer the question, How can a nature-based learning center be designed …

Implementing Outdoor And Nature-Based Learning For Infants And Toddlers, Kelly Kazeck

School of Education and Leadership Student Capstone Projects

Many early childhood educators in Minnesota are expanding outdoor and nature-based learning opportunities because of the positive developmental benefits they offer children. Time spent outdoors supports social, emotional, cognitive, and physical learning while promoting positive relationships with peers and the natural world. This capstone research found that implementing outdoor and nature-based learning requires more specialized training, safety precautions, equipment, planning, and preparation than typical indoor programming. However, much of the research focuses on preschool-aged children, although implementation with infants and toddlers presents additional challenges and requires specific supports. Therefore, this capstone project answered the question, “What can infant and toddler …

Social Emotional Learning In A High School Setting, Aaron Stack

School of Education and Leadership Student Capstone Projects

This project examined the capstone question: How can one design and implement a Social Emotional Learning (SEL) program for high school students? This topic is important as more and more students are exhibiting less desirable behaviors inside the classroom. While exploring this question, several key findings emerged. First, SEL programming in a high school setting may have a positive impact on students’ academic performance and behaviors. Second, there is no clear distinction between the effectiveness of the program as long as the SEL ideas are consistently explored. Based on these two findings, an SEL program was developed for high school …

The Causes, Effects Of, And Solutions To A Nation-Wide Reading Comprehension Decline And Answers To The Question Of What Can Teachers Do About It?, Otto Harris

School of Education and Leadership Student Capstone Projects

The purpose of this project was to research the causes and effects of the reading comprehension decline in America. The research question: What is causing this decline, and how can we combat it? stemmed from personal interest in this topic and its relevancy in the school district I taught in. Research into this topic revealed factors such as texts lacking relevance to student lives, inaccurate comprehension measurement tools being used year after year, and the lifelong effects of lowered reading comprehension on adults’ lives after high school. In response to this need, a capstone project was developed that would provide …