Digital Commons Network^™

Redshift Wrangler: Conducting A Citizen Science Study Of Extragalactic Spectroscopy, Sadie C. Coffin

Theses

I present the citizen science project Redshift Wrangler, designed to use the contributions of volunteers to analyze large samples of galaxy data and build a repository of spectroscopic measurements for various analyses. When we know how to read it, the spectrum of a galaxy can tell the story of its stellar population, distance, and interactions with any close companion galaxies. Through Redshift Wrangler, citizen science measurements become our main tool for extracting information from enormous quantities of collected spectra. Several main goals motivate this work: first, designing and launching Redshift Wrangler on citizen science platform Zooniverse to bring more people …

The Parthenon, October 11, 2023, Evan Green, Conner Woodruff, Matt Schaffer, Chayce Matheny, Victoria Ware, Shauntelle Thompson, Rafael Alfonso, Scott Price

The Parthenon

No abstract provided.

Neuronal Nadph Oxidase Is Required For Neurite Regeneration Of Aplysia Bag Cell Neurons, S.M. Sabbir Alam, Yuichiro Watanabe, Brooke L. Steeno, Soumyajit Dutta, Halie A. Szilagyi, Alexander Wei, Daniel M. Suter

Department of Chemistry Faculty Publications

NADPH oxidase (Nox), a major source of reactive oxygen species (ROS), is involved in neurodegeneration after injury and disease. Nox is expressed in both neuronal and non-neuronal cells and contributes to an elevated ROS level after injury. Contrary to the well-known damaging effect of Nox-derived ROS in neurodegeneration, recently a physiological role of Nox in nervous system development including neurogenesis, neuronal polarity, and axonal growth has been revealed. Here, we tested a role for neuronal Nox in neurite regeneration following mechanical transection in cultured Aplysia bag cell neurons. Using a novel hydrogen peroxide (H2O2)-sensing dye, 5′-(p-borophenyl)-2′-pyridylthiazole pinacol ester (BPPT), we …

Bill Bargeman Oral History, Bill Bargeman, Lorenzo Spaccarelli

Raymond College

No abstract provided.

Blood Biomarker-Based Classification Study For Neurodegenerative Diseases, Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li

Peninsula Medical School

As the population ages, neurodegenerative diseases are becoming more prevalent, making it crucial to comprehend the underlying disease mechanisms and identify biomarkers to allow for early diagnosis and effective screening for clinical trials. Thanks to advancements in gene expression profiling, it is now possible to search for disease biomarkers on an unprecedented scale.Here we applied a selection of five machine learning (ML) approaches to identify blood-based biomarkers for Alzheimer's (AD) and Parkinson's disease (PD) with the application of multiple feature selection methods. Based on ROC AUC performance, one optimal random forest (RF) model was discovered for AD with 159 gene …

Usp1 Promotes Cholangiocarcinoma Progression By Deubiquitinating Parp1 To Prevent Its Proteasomal Degradation, Deng Yong Zhang, Yan Zhu, Qiong Wu, Shuoshuo Ma, Yang Ma, Zheng Chao Shen, Zhonglin Wang, Wanliang Sun, Yong Chun Zhou, Dongdong Wang, Shuo Zhou, Zhong Liu, Lawrence N Kwong, Zheng Lu

Faculty, Staff and Student Publications

Despite its involvement in various cancers, the function of the deubiquitinase USP1 (ubiquitin-specific protease 1) is unexplored in cholangiocarcinoma (CCA). In this study, we provide evidence that USP1 promotes CCA progression through the stabilization of Poly (ADP-ribose) polymerase 1 (PARP1), consistent with the observation that both USP1 and PARP1 are upregulated in human CCA. Proteomics and ubiquitylome analysis of USP1-overexpressing CCA cells nominated PARP1 as a top USP1 substrate. Indeed, their direct interaction was validated by a series of immunofluorescence, co-immunoprecipitation (CO-IP), and GST pull-down assays, and their interaction regions were identified using deletion mutants. Mechanistically, USP1 removes the ubiquitin …

The Effects Of Immediate Static Stretching On Exercise Induced Inflammation And Doms Following An Acute Bout Of Eccentric Exercise Of The Triceps, Valarie R. Dimartino

Seton Hall University Dissertations and Theses (ETDs)

Introduction: Delayed onset muscle soreness (DOMS) is caused by the body's immune system attempting to heal damaged muscles, creating exercise induced inflammation. DOMS impacts exercise performance and adherence. Treatments provide temporary relief yet fail to inhibit the mechanism of inflammation. Purpose: The purpose of this quantitative investigation was to explore the effect of immediate static stretching on the inflammatory response and subsequent DOMS following an acute bout of eccentric triceps dips. Inflammation was measured via triceps girth (cm) and self-reported Visual Analog Scale (VAS) ratings of DOMS. Methods: 24 healthy adult participants (27.4 ± 7.5 yrs., 80 ± …

Nrg/Rtog 0837: Randomized, Phase Ii, Double-Blind, Placebo-Controlled Trial Of Chemoradiation With Or Without Cediranib In Newly Diagnosed Glioblastoma, Minesh Mehta

All Publications

Background: A randomized, phase II, placebo-controlled, and blinded clinical trial (NCT01062425) was conducted to determine the efficacy of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, versus placebo in combination with radiation and temozolomide in newly diagnosed glioblastoma.

Methods: Patients with newly diagnosed glioblastoma were randomly assigned 2:1 to receive (1) cediranib (20 mg) in combination with radiation and temozolomide; (2) placebo in combination with radiation and temozolomide. The primary endpoint was 6-month progression-free survival (PFS) based on blinded, independent radiographic assessment of postcontrast T1-weighted and noncontrast T2-weighted MRI brain scans and was tested using …

Exploring Low-Income, Black Fathers' Strengths And Barriers To Positive Change Using Qualitative Methods, Katie N. Russell, Ashley Withrow, Laura A. Voith, Carmen Vernon, Hyunjune Lee, Sherise Mckinney

Faculty Scholarship

Objective: The goal was to explore low-income, Black fathers' personal strengths and barriers to engaged fatherhood, healthy relationships, and economic stability. Background: Fatherhood programs often rely on case management and education to promote positive fathering, healthy relationships, and economic stability. However, methods should be tailored to fit the strengths and needs of participating fathers. Low-income, Black fathers face additional challenges related to systemic discrimination and structural violence that can hinder their success. To effectively serve this group, research is required to understand their relevant strengths and barriers. Methods: Semistructured focus groups explored fathers' personal strengths and barriers specific to the …

Rosuvastatin Calcium And Tissue Engineering; An Introductory Overview, Islam M. Adel, Mohamed F. Elmeligy, Nermeen A. Elkasabgy

Bulletin of Faculty of Pharmacy Cairo University

All tissues are subjected to the risk of tissue damage. Tissue damage refers to any alteration to the structure and/or the function of that tissue. To counter tissue damage, our bodies are equipped with a self-healing mechanism aiming at restoring tissue structure and function. The underlying mechanism, however, is rather poor and slow in mammalians. Moreover, in cases of severe damage, the mechanism is insufficient to repair the damage and usually, surgical intervention is mandated. For that and more, tissue engineering was conceptualized as a multidisciplinary science field in which an implantable scaffold, loaded with cells, biological cues and/or chemical …

Deconstructing Social Constructs: Exploring Teachers’ Positionality When Teaching Race And Human Diversity In The Science Classroom, Uchenna Emenaha

Journal of Multicultural Affairs

This article reports on how four urban high school biology teachers’ positionality impacts their experiences when teaching culturally responsive lessons on race and human diversity. Teachers in the study taught a two-week genetics intervention lesson on race and human diversity, then participated in individual and focus group interviews. Interview transcripts were analyzed using thematic analysis. Results reveal that teachers who were empowered by their racial positionality and had prior professional development in culturally responsive pedagogy (CRP) were more likely to believe that science instruction can be used to address unscientific misconceptions amongst high school students. These findings give credence to …

Graduate Student Instructors Coping Strategies And Concurrent Impact On Learning, Teaching, And Research, Razak K. Dwomoh, Boatemaa Tawiah-Sarpong

Journal of Multicultural Affairs

Acculturation stress is ubiquitous among international students. There is a preponderance of the use of social support in dealing with stressors by international students. This paper investigates Ghanaian graduate student instructors’ (GGSIs) coping strategies for mitigating stress in learning, teaching, and research. Primary data collection was in-depth semi-structured interviews. Focus group discussions served as complementary data. Seven participants were purposefully selected using a criterion-based selection from a midwestern U.S. public university. Thematic analysis yielded substantial results. The results show that GGSIs use social support for learning, not teaching or research. Preferable strategies for teaching are professional work ethics and setting …

The Animal In The Wild In Hwang Sun-Mi’S The Hen Who Dreamed She Could Fly, Sarah Yoon

CLCWeb: Comparative Literature and Culture

Hwang Sun-mi’s The Hen Who Dreamed She Could Fly has become a contemporary classic children’s story in Korea since its original publication in 2000. Since then, the story has been translated and redesigned with new illustrations in almost thirty different countries (Y. Kim). The Hen Who Dreamed She Could Fly centers on a hen that raises a duckling as her “baby,” with the story drawing upon a rich reservoir of cultural associations between humans and nature in East Asian traditions. In this story, the hen leaves the human-dominated barnyard, based on profit, exploitation, and competition, for a reconnection with moral …

Recent Advances In Crispr/Cas9-Assisted Gene Therapy, Apeksha Srivastava, Shikha Chauhan, Vishal Ahuja

Karbala International Journal of Modern Science

CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) is an exponentially growing tool with wide-spread applications in therapeutics like gene modifications that focus on altering the hereditary material to repair or eliminate any defective gene-causing diseases like cancer, AIDS (Acquired immunodeficiency syndrome), etc. It also includes the identification of the target sequence with the help of sgRNA followed by the substitution of a malfunction-ing gene with a normal version. It offers high efficiency, specificity, and post-gene-editing efficacy, but have also some off-target impressions, and immunogenic effects. The contribution of CRISPR/Cas9 has already been proved primarily in in-vitro studies using animal germ …

Optical, Structural, And Electrochemical Properties Of P3ht:Y6 Photoactive Layer For Organic Photovoltaics, Hassan Tarikhum B., Furqan Almyahi, Basil Ali

Karbala International Journal of Modern Science

Recently, organic photovoltaics (OPV) have emerged as a promising technology for environmentally friendly energy production. Achieving high performance in OPV requires the discovery of novel compounds. This article aims to study the optical, structural, electrochemical, and electrical properties of a P3HT:Y6 blend. The UV-visible spectra of the blend provided insight into how composition affects the optoelectronic properties of OPV devices. The optimised P3HT:Y6 ratio (0.6:1) resulted in the largest redshift and the highest absorption intensity. Raman and X-ray diffraction tests showed low aggregation and low crystallinity of the polymer P3HT as Y6 content increased. In the OPV devices, the best …

Estimation Of Water Quality Of Dikhu River Of Nagaland Through A Combination Of Water Quality Index And Principal Component Analysis Techniques., Lanuyanger Longchar, Wati Temjen, Khikeya Semy, Wati Lemla

Karbala International Journal of Modern Science

Monitoring the physico-chemical attributes of water is essential for determining water quality. The present study explores the effect of various anthropogenic factors on the quality of Dikhu River, Nagaland. Water samples from three sampling stations were compared against three standards: Indian Council of Medical Research, Bureau of Indian Standards, and World Health Organization. Although all parameters were within the permissible limits, the Water Quality Index categorized all sites during the rainy season as "poor quality", highlighting anthropogenic impacts. A principal component analysis created a Minimum Data Set (MDS) explaining 100%, 93.27%, and 96.26% of the total variance for the three …

Icc Agenda 10-10-23, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Programs Agenda 10-10-23, Angela Brock

Programs Committee (PC)

No abstract provided.

Approved Courses 10-10-23, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Engineering Students Emotional Intelligence And Neuro-Linguistics Programming (Nlp) As Developmental Tool, Ahlem Khefacha, Beatrix Séllei

Research Papers

This article investigates the strengths and weaknesses of engineering students' emotional intelligence (EI) and the possibility of using neurolinguistics programming (NLP) as a developmental tool. Students' emotional intelligence was assessed using the Bar-On Emotional Quotient Inventory (EQ-I) with 5 points Likert scale. Firstsemester engineering students were approached by part of a broader study at the Budapest University of Technology during 2018-2022. In the article, we describe the emotional intelligence profile of more than 3600 students in various fields of engineering. NLP professionals around the world filled out the second questionnaire. We got answers from 35 professionals based in Tunisia, Hungary, …

Why Do Students Dislike Peer Feedback?, Becky Selwyn, Joel Ross, Sean Lancastle

Research Papers

Engineers are required to communicate in a range of formats, including written reports, but this skill does not come naturally to undergraduates. Typical approaches to teaching writing skills require small class sizes, expert staff, and multiple cycles of feedback. These approaches, while successful, are difficult to scale and do not always result in students being able to transfer their writing skills to other units/topics.

The School of Civil, Aerospace, and Mechanical Engineering at the University of Bristol teaches writing skills mainly within a single 20-credit first-year unit, delivered to 550-650 students per year. Students are required to complete a number …

Comparing Xr And Digital Flipped Methods To Meet Learning Objectives, Krys Bangert, Edward Browncross, Matteo Di Benedetti, Harry Day, Andrew Garrard

Research Papers

Digital learning has become increasingly important over the last decade as students and educators adopt new types of technology to keep up with emerging trends. The advent of the Covid-19 pandemic accelerated this rate of change in the higher education sector, leading to remote laboratory experiences and video conferencing becoming increasingly normal. In the wake of this transition, the priority is to understand how these technologies can be blended into existing teaching methodologies, in a complementary way, that enhances the student’s pedagogical experience. The upcoming study will compare three digital-based learning simulations to see which has the most beneficial effect …

Rethinking Evolution Of Active Learning In The Hybrid/Online Engineering Education In The Post-Covid-19 Era: A Quantitative Keyword Co-Occurrence Analysis, Yiwen Xu, Thitiwat Piyatamrong, Abel Nyamapfene

Research Papers

In response to COVID-19, education witnessed a rapid shift to online and virtual platforms. Our previous research has raised questions about the efficacy of these methods for hands-on practice and active learning experiences - crucial elements of engineering education. Emergent solutions like online laboratories and virtual field trips have led to the rise of a hybrid learning era in the post-pandemic context. This change necessitates a reassessment of active learning in hybrid/online engineering education. In this study, we examine recent literature on online and virtual education during and post-COVID-19 to redefine and reevaluate strategies for engaging students actively. We propose …

Rethinking The Nature Of Experimental Learning: Moving Beyond Conventional Laboratory Experiences, David Lowe

Research Papers

Laboratory experimentation is an important educational tool across many disciplines, providing a mechanism for students to enhance their understanding of the relationships between theoretical models and physical reality. However, whilst laboratories are used extensively, the existing approaches to experimental learning have evolved little in the last 100 years, the intended learning outcomes are often poorly articulated and the connection between the learning outcomes and the student experiences is unclear. These limitations hasve meant that the development of laboratory experiences has tended to be driven by a combination of history, the capability of physical laboratory environments, and technological opportunity (e.g. the …

The Role Of Earth System Literacy In Sustainability Education For Engineers, Sudeshna Basu

Research Papers

Engineers should be able to demonstrate sustainability competencies transcending their specialised discipline. But all cross-disciplinary sustainability competencies are not targeted adequately in engineering education and are often mismatched with competencies required by engineers in their professional roles. Future engineers should have an understanding of the environment alongside technical knowledge, with all engineering design and product showing consideration to sustainability. The study of the Earth system is relevant to the understanding of environmental issues and the interplay between the sub-systems of the Earth (atmosphere, geosphere, biosphere and hydrosphere) . Yet, integration of Earth system literacy in the engineering curriculum has received …

Study Success And Failure Of Stem Students And The Connection To Their Learning Habits, Fabian Mumenthaler, Patrick Jermann, Cécile Hardebolle, Roland Tormey

Research Papers

With the educational expansion, ever more students start a tertiary degree. At the École Polytechnique Fédérale de Lausanne, an engineering school, the number of bachelor students increased from 3’713 in 2010 to 6’330 in 2022. However, in Switzerland, a considerable number of students fail to achieve their first university degree – and failure rates are even higher at engineering schools. A weak mathematics background is often identified as the main reason for dropout. In this paper, we are interested to test whether inadequate learning habits are also responsible to some extent for first-year dropouts. To this end, we matched admission …

Sustainable Engineering Education Embedded Curricula Research Project, Anthony Edward Smith, Alfredo Soeiro, Ragna Ann Berge, Tamer Atabarut, John Atkinson, Patricia Caratozzolo

Research Papers

A previous conference paper with case study report findings began this research so as to inform and be of use to the International Association for Continuing Engineering Education (IACEE) institutions and its membership on the importance of embedding sustainability in all engineering education courses from the beginning to the end of the Degree and beyond into Continuing Engineering Education (CEE) . This present project continues to qualitatively research and investigate the extent to which and how Engineering Learning Curricula (ELC) incorporate and embed sustainability as central to the future work practice of all engineers. Specifically, as the project takes a …

College Faculty In The News: Oct. 10, 2023, University Of Dayton

College of Arts and Sciences Newsroom

News agencies across the region, the nation and throughout the world often reach out to our faculty experts for their perspectives on today's issues.

Expert-Novice Differences In Electrical Circuit Analysis Based On The Order Of Attention, Amit Mahendra Paikrao, Ritayan Mitra

Research Papers

The difference between experts and novices during problem-solving has been established in several domains. However, in electrical engineering, studies are sparse. This study compares experts and novices in an introductory electrical engineering course. Four novices (students) and three experts (teachers) were made to solve eight circuit problems with a concurrent think-aloud protocol conducted remotely due to COVID restrictions in India at the time of the study. Experts predominantly followed the direction of the current showing a working-forward strategy. Conversely, Novices displayed a means-end approach by jumping to mathematical calculations more than anything else. In addition, the arrangement of complex circuits …

Northeast Tennessee Educators’ Perceptions Of Academic Outcomes Of High School Students Who Completed A Community-Based, Resilience-Informed Course Presented At School, Carla Whiles

Ed.D. Dissertations

Adverse childhood experiences negatively affected the mental and physical health of adults and children and were linked to cognitive difficulties and decreased academic outcomes at all levels of education. Resilience, the ability for one to bounce back from adversity, was widely accepted to mitigate the negative effects of adversities and resilience intervention programs were becoming more common in schools. The purpose of this qualitative interpretive study was to examine northeast Tennessee educators’ perceptions of the academic outcomes of high school students who completed a community-based, resilience-informed course presented at school. After conducting semi-structured interviews with 11 participants, I discovered the …