Digital Commons Network^™

Comparing Xr And Digital Flipped Methods To Meet Learning Objectives, Krys Bangert, Edward Browncross, Matteo Di Benedetti, Harry Day, Andrew Garrard

Research Papers

Digital learning has become increasingly important over the last decade as students and educators adopt new types of technology to keep up with emerging trends. The advent of the Covid-19 pandemic accelerated this rate of change in the higher education sector, leading to remote laboratory experiences and video conferencing becoming increasingly normal. In the wake of this transition, the priority is to understand how these technologies can be blended into existing teaching methodologies, in a complementary way, that enhances the student’s pedagogical experience. The upcoming study will compare three digital-based learning simulations to see which has the most beneficial effect …

Rethinking Evolution Of Active Learning In The Hybrid/Online Engineering Education In The Post-Covid-19 Era: A Quantitative Keyword Co-Occurrence Analysis, Yiwen Xu, Thitiwat Piyatamrong, Abel Nyamapfene

Research Papers

In response to COVID-19, education witnessed a rapid shift to online and virtual platforms. Our previous research has raised questions about the efficacy of these methods for hands-on practice and active learning experiences - crucial elements of engineering education. Emergent solutions like online laboratories and virtual field trips have led to the rise of a hybrid learning era in the post-pandemic context. This change necessitates a reassessment of active learning in hybrid/online engineering education. In this study, we examine recent literature on online and virtual education during and post-COVID-19 to redefine and reevaluate strategies for engaging students actively. We propose …

Rethinking The Nature Of Experimental Learning: Moving Beyond Conventional Laboratory Experiences, David Lowe

Research Papers

Laboratory experimentation is an important educational tool across many disciplines, providing a mechanism for students to enhance their understanding of the relationships between theoretical models and physical reality. However, whilst laboratories are used extensively, the existing approaches to experimental learning have evolved little in the last 100 years, the intended learning outcomes are often poorly articulated and the connection between the learning outcomes and the student experiences is unclear. These limitations hasve meant that the development of laboratory experiences has tended to be driven by a combination of history, the capability of physical laboratory environments, and technological opportunity (e.g. the …

The Role Of Earth System Literacy In Sustainability Education For Engineers, Sudeshna Basu

Research Papers

Engineers should be able to demonstrate sustainability competencies transcending their specialised discipline. But all cross-disciplinary sustainability competencies are not targeted adequately in engineering education and are often mismatched with competencies required by engineers in their professional roles. Future engineers should have an understanding of the environment alongside technical knowledge, with all engineering design and product showing consideration to sustainability. The study of the Earth system is relevant to the understanding of environmental issues and the interplay between the sub-systems of the Earth (atmosphere, geosphere, biosphere and hydrosphere) . Yet, integration of Earth system literacy in the engineering curriculum has received …

Study Success And Failure Of Stem Students And The Connection To Their Learning Habits, Fabian Mumenthaler, Patrick Jermann, Cécile Hardebolle, Roland Tormey

Research Papers

With the educational expansion, ever more students start a tertiary degree. At the École Polytechnique Fédérale de Lausanne, an engineering school, the number of bachelor students increased from 3’713 in 2010 to 6’330 in 2022. However, in Switzerland, a considerable number of students fail to achieve their first university degree – and failure rates are even higher at engineering schools. A weak mathematics background is often identified as the main reason for dropout. In this paper, we are interested to test whether inadequate learning habits are also responsible to some extent for first-year dropouts. To this end, we matched admission …

Sustainable Engineering Education Embedded Curricula Research Project, Anthony Edward Smith, Alfredo Soeiro, Ragna Ann Berge, Tamer Atabarut, John Atkinson, Patricia Caratozzolo

Research Papers

A previous conference paper with case study report findings began this research so as to inform and be of use to the International Association for Continuing Engineering Education (IACEE) institutions and its membership on the importance of embedding sustainability in all engineering education courses from the beginning to the end of the Degree and beyond into Continuing Engineering Education (CEE) . This present project continues to qualitatively research and investigate the extent to which and how Engineering Learning Curricula (ELC) incorporate and embed sustainability as central to the future work practice of all engineers. Specifically, as the project takes a …

College Faculty In The News: Oct. 10, 2023, University Of Dayton

College of Arts and Sciences Newsroom

News agencies across the region, the nation and throughout the world often reach out to our faculty experts for their perspectives on today's issues.

Expert-Novice Differences In Electrical Circuit Analysis Based On The Order Of Attention, Amit Mahendra Paikrao, Ritayan Mitra

Research Papers

The difference between experts and novices during problem-solving has been established in several domains. However, in electrical engineering, studies are sparse. This study compares experts and novices in an introductory electrical engineering course. Four novices (students) and three experts (teachers) were made to solve eight circuit problems with a concurrent think-aloud protocol conducted remotely due to COVID restrictions in India at the time of the study. Experts predominantly followed the direction of the current showing a working-forward strategy. Conversely, Novices displayed a means-end approach by jumping to mathematical calculations more than anything else. In addition, the arrangement of complex circuits …

Northeast Tennessee Educators’ Perceptions Of Academic Outcomes Of High School Students Who Completed A Community-Based, Resilience-Informed Course Presented At School, Carla Whiles

Ed.D. Dissertations

Adverse childhood experiences negatively affected the mental and physical health of adults and children and were linked to cognitive difficulties and decreased academic outcomes at all levels of education. Resilience, the ability for one to bounce back from adversity, was widely accepted to mitigate the negative effects of adversities and resilience intervention programs were becoming more common in schools. The purpose of this qualitative interpretive study was to examine northeast Tennessee educators’ perceptions of the academic outcomes of high school students who completed a community-based, resilience-informed course presented at school. After conducting semi-structured interviews with 11 participants, I discovered the …

Nurturing Community: Using Community-Based Service Learning In Biopharmaceutical Engineering Education., Miriam I Jiménez-Pérez, Yocanxóchitl Perfecto-Avalos., Mariana C Orellana- Haro

Research Papers

This project evaluates the use of CBSL as a strategy for teaching clinical investigation in the development of biopharmaceutical products based on the nutritional needs of children of a low-income community. To achieve this purpose, our students formulated various functional foods that provided the necessary nutrients for the children in the target community. Afterwards, they drafted the corresponding clinical protocols for each formulation, considering possible ethical implications. The academic evaluation was based on the comparison of courses with and without CBSL. The study found that students showed a slight improvement in academic performance with CBSL. This suggests that CBSL can …

Can Oral Examinations Replace Written Examinations?, Zixuan Mu, Fred Marquis

Research Papers

The purpose of any assessment is to determine students’ learning. While oral examinations have been adopted in many education systems, such as the PhD thesis viva and medical assessments (Huxham, Campbell, and Westwood 2012), they are rarely used in undergraduate engineering courses (Baghdadchi et al. 2022) which traditionally rely on written papers. This is not surprising given, generally, the large cohort sizes and the need to efficiently conduct such examinations in a timely manner. It has been shown that widening the range of assessments that a student experiences can lead to a more comprehensive development of the student (Rust 2005) …

Emerging Trends, Approaches And Challenges In Engineering Education In The Uk, Stella Fowler, Ines Direito, Kate Bellingham, John Mitchell

Research Papers

Worldwide, engineering educators are searching for approaches, pedagogies and change strategies to develop programmes that will equip their graduates to be successful engineers, effective engineering leaders and catalysts for social 1 S. Fowler, [email protected] development. In the UK, focus largely rests on new pathway initiatives and new Higher Education (HE) institutions. There is little shared understanding of the established sector’s evolution from a maths and science heavy curricula to the innovative and world-leading models of engineering education found in the UK HE sector today.

Teaching Sustainability Through A Role-Play Case Study Of E-Scooter Use On College Campuses, Shruti Mehta, Ashish Hingle, Aditya Johri

Research Papers

Sustainability has developed into a pressing concern across disciplinary domains, and the need for teaching sustainability concepts to students has grown significantly. In this paper, we present a research study that assessed undergraduate students’ understanding of sustainability after participating in a case study discussion. We designed and implemented a role-play case study of e-scooters on a college campus. The case facilitated “near transfer,” as it focused on an issue most students have personally experienced. Furthermore, the role-play component simulated a real-world context and allowed students to take different perspectives related to the topic, resulting in a discussion of social, political, …

Inclusive Engineering Classrooms: Student Teaching Assistants’ Perspectives, Joelyn De Lima, Siara Isaac, Helena Kovacs

Research Papers

Inclusive teaching is the intentional practice of recognising biases, working to mitigate their impact, and ensuring that students have equitable learning opportunities. In addition to improving students' sense of belonging and self efficacy, inclusive teaching improves retention, improves academic performance, and reduces achievement gaps. In many large enrollment introductory classrooms, student teaching assistants (TAs) contribute to the classroom climate in addition to the teachers and the students. In this qualitative study, 262 TAs were asked about their teaching strengths, areas that need improvement, obstacles, and ideas about their role in reducing incidents of discrimination or harassment. We coded their open-ended …

Embedding Competencies In Sustainability And Authentic Learning Experiences In Food Science Education Through A Study Program-Driven Approach, Anita Nordeng Jakobsen, Sunniva Hoel, Ida-Johanne Jensen

Research Papers

The food sector is experiencing a substantial shift towards Industry 4.0 regarding technological solutions to ensure efficient and sustainable food production. To face the required changes and be able to influence and change existing systems, future candidates must have solid capabilities in their respective subject areas as well as generic skills such as critical thinking, reflection, communication, and teamwork skills. At NTNU, a program-driven approach for embedding sustainability and authentic learning experiences in the bachelor program of Food Science, technology and sustainability was conducted. Thematic groups of staff members developed learning outcomes and learning- and assessment methods to ensure coherence …

Is “Improving The Quality Of Life” The Only Sustainability Issue That Is Related To Engineering? - Exploring Engineering Students’ Conceptions Of Sustainability, Lillian Yun Yung Luk, Inês Direito, John Mitchell, Kate Roach

Research Papers

UNESCO’s (2021) report on engineering for sustainable development has emphasized the critical role of engineers in achieving the 17 Sustainable Development Goals (SDGs). Yet, there is a lack of clarity about the conceptualization or definition of sustainability (Moore et al., 2017), which makes it difficult to integrate sustainability into the curriculum. While Walshe (2008) conducted a study on high school students’ conceptions of sustainability in the UK, there appears to be a lack of research conducted in the context of higher education. The study presented in this paper explores engineering students’ understanding of sustainability in engineering and how it is …

The Stability Of Pre-Enrolment Prediction Of Academic Achievement: Criterion-Referencing Versus Norm-Referencing, Jolan Hanssens, Carolien Van Soom, Greet Langie

Research Papers

Positioning tests are organized in Flanders for prospective STEM students. They provide a low-stakes opportunity to assess their level of starting competences before enrolment. Predictive validity for subsequent academic achievement is an important quality measure of these positioning tests. However, the content of the tests varies over the years. This could be problematic for making accurate predictions based on data from previous years. Therefore, the objective of this study is to compare the stability over time of the predictions of academic achievement using either criterionreferenced (absolute grading) or norm-referenced (relative grading) positioning test grades of engineering and science students. Comparisons …

Trauma-Informed Educational Leadership: A Case Study, Robyn Scott

Doctor of Education in Educational Leadership Dissertations

This research study offers an exploratory examination into the lived experiences of educational leaders managing the implementation and facilitation of Trauma-Skilled Schools (TSS) in the post-COVID-19 pandemic context. This study details the unique challenges and opportunities experienced while planning and executing TSS, aiming to equip school staff to better address trauma-affected behaviors. Utilizing case study methods, including in-depth interviews and document analysis, this research uncovers practices, strategies, and challenges, offering an insider's perspective on leading TSS initiatives. Findings indicate a necessity for comprehensive, job-embedded professional learning, continuous support from educational leadership, and organizational change in school policy, practice, and mindset, …

Paired Liver:Plasma Pfas Concentration Ratios From Adolescents In The Teen-Labs Study And Derivation Of Empirical And Mass Balance Models To Predict And Explain Liver Pfas Accumulationn, Brittney O Baumert, Fabian C Fischer, Flemming Nielsen, Philippe Grandjean, Scott Bartell, Nikos Stratakis, Douglas I Walker, Damaskini Valvi, Rohit Kohli, Thomas Inge, Justin Ryder, Todd Jenkins, Stephanie Sisley, Stavra Xanthakos, Sarah Rock, Michele A La Merrill, David Conti, Rob Mcconnell, Lida Chatzi

Faculty, Staff and Students Publications

Animal studies have pointed at the liver as a hotspot for per- and polyfluoroalkyl substances (PFAS) accumulation and toxicity, however, these findings have not been replicated in human populations. We measured concentrations of seven PFAS in matched liver and plasma samples collected at the time of bariatric surgery from 64 adolescents in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study. Liver:plasma concentrations ratios were perfectly explained (r2 > 0.99) in a multi-linear regression (MLR) model based on toxicokinetic (TK) descriptors consisting of binding to tissue constituents and membrane permeabilities. Of the seven matched plasma and liver PFAS concentrations compared in this …

Antithrombotic Nanoparticles And Methods For Treating Necrotizing Enterocolitis, Akhil Maheshwari, Samuel Wickline, Kopperuncholan Namachivayam, Hua Pan

USF Patents

The present disclosure is directed to antithrombotic nanoparticles and methods of treating necrotizing enterocolitis.

Program Review Report 10-10-23, Angela Brock

Program Review Committee

No abstract provided.

Leveraging The Strengths Of Citizen Science And Structured Surveys To Achieve Scalable Inference On Population Size, Andrew N. Stillman, Paige E. Howell, Guthrie S. Zimmerman, Emily R. Bjerre, Brian A. Millsap, Orin J. Robinson, Daniel Fink, Erica F. Stuber, Viviana Ruiz-Gutierrez

Wildland Resources Faculty Publications

1. Population size is a key metric for management and policy decisions, yet wildlife monitoring programmes are often limited by the spatial and temporal scope of surveys. In these cases, citizen science data may provide complementary information at higher resolution and greater extent.

2. We present a case study demonstrating how data from the eBird citizen science programme can be combined with regional monitoring efforts by the US Fish and Wildlife Service to produce high-resolution estimates of golden eagle abundance. We developed a model that uses aerial survey data from the western United States to calibrate high-resolution annual estimates of …

Characteristics And Prognostic Impact Of Idh Mutations In Aml: A Cog, Swog, And Ecog Analysis., Sara Zarnegar-Lumley, Todd A. Alonzo, Robert B. Gerbing, Megan Othus, Zhuoxin Sun, Rhonda E. Ries, Jim Wang, Amanda Leonti, Matthew A. Kutny, Fabiana Ostronoff, Jerald P. Radich, Frederick R. Appelbaum, Era L. Pogosova-Agadjanyan, Kristen O'Dwyer, Martin S. Tallman, Mark Litzow, Ehab Atallah, Todd M. Cooper, Richard A. Aplenc, Omar Abdel-Wahab, Alan S. Gamis, Selina Luger, Harry Erba, Ross Levine, E Anders Kolb, Derek L. Stirewalt, Soheil Meshinchi, Katherine Tarlock

Manuscripts, Articles, Book Chapters and Other Papers

Somatic mutations in isocitrate dehydrogenase (IDH) genes occur frequently in adult acute myeloid leukemia (AML) and less commonly in pediatric AML. The objective of this study was to describe the prevalence, mutational profile, and prognostic significance of IDH mutations in AML across age. Our cohort included 3141 patients aged betweenChildren's Cancer Group/Children's Oncology Group (n = 1872), Southwest Oncology Group (n = 359), Eastern Cooperative Oncology Group (n = 397) trials, and in Beat AML (n = 333) and The Cancer Genome Atlas (n = 180) genomic characterization cohorts. We retrospectively analyzed patients in 4 age groups (age range, n): …

Inducing Mitotic Catastrophe As A Therapeutic Approach To Improve Outcomes In Ewing Sarcoma., Soumya M. Turaga, Vikalp Vishwakarma, Stacey L. Hembruff, Benjamin K. Gibbs, Priya Sabu, Rajni V. Puri, Harsh B. Pathak, Glenson Samuel, Andrew K. Godwin

Manuscripts, Articles, Book Chapters and Other Papers

Ewing sarcoma (EWS) is an aggressive pediatric malignancy of the bone and soft tissues in need of novel therapeutic options. To identify potential therapeutic targets, we focused on essential biological pathways that are upregulated by EWS-FLI1, the primary oncogenic driver of EWS, including mitotic proteins such as Aurora kinase A (AURKA) and kinesin family member 15 (KIF15) and its binding partner, targeting protein for Xklp2 (TPX2). KIF15/TPX2 cooperates with KIF11, a key mitotic kinesin essential for mitotic spindle orientation. Given the lack of clinical-grade KIF15/TPX2 inhibitors, we chose to target KIF11 (using SB-743921) in combination with AURKA (using VIC-1911) given …

A Thermodynamic Analysis Of Clc Transporter Dimerization In Lipid Bilayers, Rahul Chadda, Taeho Lee, Robyn Mahoney-Kruszka, Elizabeth G Kelley, Nathan Bernhardt, Priyanka Sandal, Janice L Robertson

2020-Current year OA Pubs

The CLC-ec1 chloride/proton antiporter is a membrane-embedded homodimer with subunits that can dissociate and associate, but the thermodynamic driving forces favor the assembled dimer at biological densities. Yet, the physical reasons for this stability are confounding as dimerization occurs via the burial of hydrophobic interfaces away from the lipid solvent. For binding of nonpolar surfaces in aqueous solution, the driving force is often attributed to the hydrophobic effect, but this should not apply in the membrane since there is very little water. To investigate this further, we quantified the thermodynamic changes associated with CLC dimerization in membranes by carrying out …

The Colonisation Of The Tyrrhenian Islands By Hydraena Water Beetles, With Hydraena Reflexa Rey, 1884 Reinstated As A Valid Species Endemic To Corsica And Sardinia (Coleoptera, Hydraenidae), David T. Bilton, Ignacio Ribera, Adrián Villastrigo

School of Biological and Marine Sciences

The biotas of old islands formed from continental terranes usually have a more complex biogeographical history than those of young oceanic islands, including taxa which have originated by vicariance and/or colonisation, over a variety of timescales. The Tyrrhenian Islands of Corsica, Sardinia and the Tuscan Archipelago in the Mediterranean have a complex geological history, shaped by interac-tions between the African and Eurasian plates since the Mesozoic. Our understanding of the historical biogeography of Tyrrhenian endemics remains limited for many groups, including freshwater invertebrates. Here we use a time-calibrated phylogeny, derived from mitochondrial and nuclear DNA sequence data, to explore the …

Academic Senate - Agenda, 10/10/2023, Academic Senate

Academic Senate Agendas

No abstract provided.

Phase Shift Between Joint Rotation And Actuation Reflects Dominant Forces And Predicts Muscle Activation Patterns, R. D. Quinn, Hillel J. Chiel

Faculty Scholarship

During behavior, the work done by actuators on the body can be resisted by the body's inertia, elastic forces, gravity, or viscosity. The dominant forces that resist actuation have major consequences on the control of that behavior. In the literature, features and actuation of locomotion, for example, have been successfully predicted by nondimensional numbers (e.g. Froude number and Reynolds number) that generally express the ratio between two of these forces (gravitational, inertial, elastic, and viscous). However, animals of different sizes or motions at different speeds may not share the same dominant forces within a behavior, making ratios of just two …

Integrated Molecular Characterization Of Intraductal Papillary Mucinous Neoplasms: An Nci Cancer Moonshot Precancer Atlas Pilot Project, Alexander Semaan, Vincent Bernard, Justin Wong, Yuki Makino, Daniel B Swartzlander, Kimal I Rajapakshe, Jaewon J Lee, Adam Officer, Christian Max Schmidt, Howard H Wu, Courtney L Scaife, Kajsa E Affolter, Daniela Nachmanson, Matthew A Firpo, Michele Yip-Schneider, Andrew M Lowy, Olivier Harismendy, Subrata Sen, Anirban Maitra, Yasminka A Jakubek, Paola A Guerrero

Faculty, Staff and Student Publications

Intraductal papillary mucinous neoplasms (IPMN) are cystic precursor lesions to pancreatic ductal adenocarcinoma (PDAC). IPMNs undergo multistep progression from low-grade (LG) to high-grade (HG) dysplasia, culminating in invasive neoplasia. While patterns of IPMN progression have been analyzed using multiregion sequencing for somatic mutations, there is no integrated assessment of molecular events, including copy-number alterations (CNA) and transcriptional changes that accompany IPMN progression. We performed laser capture microdissection on surgically resected IPMNs of varying grades of histologic dysplasia obtained from 23 patients, followed by whole-exome and whole-transcriptome sequencing. Overall, HG IPMNs displayed a significantly greater aneuploidy score than LG lesions, with …

First-In-Human, Phase I Dose-Escalation And Dose-Expansion Study Of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan In Non-Small-Cell Lung Cancer: Tropion-Pantumor01, Toshio Shimizu, Jacob Sands, Kiyotaka Yoh, Alexander Spira, Edward B Garon, Satoru Kitazono, Melissa L Johnson, Funda Meric-Bernstam, Anthony W Tolcher, Noboru Yamamoto, Jon Greenberg, Yui Kawasaki, Hong Zebger-Gong, Fumiaki Kobayashi, Penny Phillips, Aaron E Lisberg, Rebecca S Heist

Faculty, Staff and Student Publications

PURPOSE: This first-in-human, dose-escalation and dose-expansion study evaluated the safety, tolerability, and antitumor activity of datopotamab deruxtecan (Dato-DXd), a novel trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugate in solid tumors, including advanced non-small-cell lung cancer (NSCLC).

PATIENTS AND METHODS: Adults with locally advanced/metastatic NSCLC received 0.27-10 mg/kg Dato-DXd once every 3 weeks during escalation or 4, 6, or 8 mg/kg Dato-DXd once every 3 weeks during expansion. Primary end points were safety and tolerability. Secondary end points included objective response rate (ORR), survival, and pharmacokinetics.

RESULTS: Two hundred ten patients received Dato-DXd, including 180 in the 4-8 mg/kg dose-expansion cohorts. …