Digital Commons Network^™

Gene-Educational Attainment Interactions In A Multi-Population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa De Las Fuentes, Karen L. Schwander, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Yun Ju Sung, Patricia B. Munroe, Clint L. Miller, Hugo Aschard, Stella Aslibekyan, Traci M. Bartz, Lawrence F. Bielak, Jin Fang Chai, Ching Yu Cheng, Rajkumar Dorajoo, Mary F. Feitosa, Xiuqing Guo, Fernando P. Hartwig, Andrea Horimoto, Ivana Kolčić, Elise Lim, Yongmei Liu, Alisa K. Manning, Jonathan Marten, Solomon K. Musani, Raymond Noordam, Sandosh Padmanabhan, Tuomo Rankinen, Melissa A. Richard, Paul M. Ridker, Albert V. Smith, Dina Vojinovic, Alan B. Zonderman

Faculty Publications

Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. Methods: A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment interactions in up to 226,315 individuals from five population groups. We considered two educational attainment variables: “Some College” (yes/no, for any education beyond high school) and “Graduated College” (yes/no, for completing a 4-year college degree). Genome-wide significant (p < 5 × 10−8) and suggestive (p < 1 × 10−6) variants were identified in Stage 1 (in up to 108,784 individuals) through genome-wide analysis, and those variants were followed up in Stage 2 studies (in up to 117,531 individuals). Results: In combined analysis of Stages 1 and 2, we identified 18 novel lipid loci (nine for LDL, seven for HDL, and two for TG) by two degree-of-freedom (2 DF) joint tests of main and interaction effects. Four loci showed significant interaction with educational attainment. Two loci were significant only in cross-population analyses. Several loci include genes with known or suggested roles in adipose (FOXP1, MBOAT4, SKP2, STIM1, STX4), brain (BRI3, FILIP1, FOXP1, LINC00290, LMTK2, MBOAT4, MYO6, SENP6, SRGAP3, STIM1, TMEM167A, TMEM30A), and liver (BRI3, FOXP1) biology, highlighting the potential importance of brain-adipose-liver communication in the regulation of lipid metabolism. An investigation of the potential druggability of genes in identified loci resulted in five gene targets shown to interact with drugs approved by the Food and Drug Administration, including genes with roles in adipose and brain tissue. Discussion: Genome-wide interaction analysis of educational attainment identified novel lipid loci not previously detected by analyses limited to main genetic effects.

Charting The Course To Advance Dei In The Ocean Sciences A Case Study, Christopher F. D’Elia, Katherine Falls, Sibel Bargu, Linda Hooper-Bùi

Faculty Publications

The Louisiana State University College of the Coast & Environment (LSU CC&E) developed a multi-faceted strategic initiative to increase its diversity, equity, and inclusion. Elements of this initiative began one-by-one over the last decade and were aggregated into a comprehensive implementation plan—the 2020 CC&E Diversity, Equity, and Inclusion Action Plan. Based on best practices in the “physical sciences” (i.e., geosciences, including oceanography), the plan aims to augment recruitment and retention using limited resources and personnel. The long-range goal is to increase the number of PhD graduates from underrepresented groups by employing strategies that start at the 6–12th grade level. The …

Understanding The Developments In The Business Perspective Of Cloud Computing: A Multidimensional Scaling Analysis, Harsh Parekh, Huai Tzu Cheng, Andrew Schwarz

Faculty Publications

Research on cloud computing (CC) has gained a lot of momentum owing to its massive adoption. It has moved beyond the exploration of inherent capabilities to understand its disruptiveness and transformative value. In this vein, the authors conducted a comparative literature review of 101 articles to better understand the developments from previous reviews. This article serves as a replication study to evaluate the growth of the business perspective of CC. The authors identify 126 factors guiding the characteristics, adoption, governance, and business impact of the cloud. Further, they employ a rigorous analysis that situates our review at the intersection of …

Lsu General Catalog 2023-2024, Louisiana State University And Agricultural And Mechanical College

LSU General Catalog

The LSU General Catalog describes all undergraduate and graduate departments and programs with degree requirements and courses offered for each one. The LSU General Catalog includes information on registration and financial aid as well as academic services offered to all students.

The Link Between Marine Thermal Discharges And Nemopilema Nomurai Blooms Around Nuclear Power Plants, Jiawei Wu, Jie Kong, Edward A. Laws, Xin Liu, Changyun Wang, Jixin Chen, Mianrun Chen, Qingzhen Yao, Yantao Wang, Yu Zhen, Chaolun Li, Bangqin Huang

Faculty Publications

Recent research has shown that jellyfish blooms occur more frequently near nuclear power plants (NPPs), and a relationship between thermal discharges from the NPPs and the blooms has been hypothesized. There is, however, no direct evidence that links the thermal discharges with jellyfish blooms. In this study, we conducted 3 cruises (pre-bloom, bloom, and post-bloom) during July to September 2017 in the area surrounding the largest NPP in northern China. The water temperature near the cooling water outfall rose by 2 °C. Although we found no significant impact on phytoplankton abundance or community composition near the outfall, a broader analysis …

Acute Exercise Induces Distinct Quantitative And Phenotypical T Cell Profiles In Men With Prostate Cancer, Erik D. Hanson, Samy Sakkal, Lauren C. Bates-Fraser, Shadney Que, Eunhan Cho, Guillaume Spielmann, Elif Kadife, John A. Violet, Claudio L. Battaglini, Lee Stoner, David B. Bartlett, Glenn K. Mcconell, Alan Hayes

Faculty Publications

Background: Reduced testosterone levels can influence immune system function, particularly T cells. Exercise during cancer reduces treatment-related side effects and provide a stimulus to mobilize and redistribute immune cells. However, it is unclear how conventional and unconventional T cells (UTC) respond to acute exercise in prostate cancer survivors compared to healthy controls. Methods: Age-matched prostate cancer survivors on androgen deprivation therapy (ADT) and those without ADT (PCa) along with non-cancer controls (CON) completed ∼45 min of intermittent cycling with 3 min at 60% of peak power interspersed by 1.5 min of rest. Fresh, unstimulated immune cell populations and intracellular perforin …

Leaky Gut And The Ingredients That Help Treat It: A Review, Ricardo Santos Aleman, Marvin Moncada, Kayanush J. Aryana

Faculty Publications

The human body is in daily contact with potentially toxic and infectious substances in the gastrointestinal tract (GIT). The GIT has the most significant load of antigens. The GIT can protect the intestinal integrity by allowing the passage of beneficial agents and blocking the path of harmful substances. Under normal conditions, a healthy intestinal barrier prevents toxic elements from entering the blood stream. However, factors such as stress, an unhealthy diet, excessive alcohol, antibiotics, and drug consumption can compromise the composition of the intestinal microbiota and the homeostasis of the intestinal barrier function of the intestine, leading to increased intestinal …

In-Vision : Issue 11 - Jan - Dec 2023, Department Of Education Development

IN-VISION – Department of Educational Development Archives

• Message from Dr Naveed Yousuf Chair, Department of Education Development
• Faculty in Focus Dr. Sana Saeed
• Hallmark of the Year 2023
• Education Grand Rounds (EGR)
• Introductory Short Course in Health Professions Education (ISC-HPE)
• Master of Health Professions Education (MHPE)
• MHPE Elective Course
• Meet the MHPE Graduates - 2023
• Continuous Faculty Development Programme in Health Professions Education
• Other Faculty Development Initiatives
• Mega Question Review
• Faculty & Staff Highlights
• Awards & Appointments
• Meet the new DED members
• Publications
• Learning Resources
• Upcoming events
• Med Ed How to Increasing the Impact of Teaching Presentations
• Med Ed How to: Case Based Learning

Cross-Language Generalization In Language Treatment Of Multilingual Aphasia: A Meta-Analysis, Mira Goral, Monica I. Norvik, Jan Antfolk, Ioulia Agrotou, Minna Lehtonen

Publications and Research

Studies on the efficacy of language treatment for multilingual people with post-stroke aphasia and its generalization to untreated languages have produced mixed results. We conducted a systematic review and a meta- analysis to examine within- and cross-language treatment effects and the variables that affect them. We searched PubMed, PsycINFO, CINAHL, and Google Scholar (February 2020; January 2023), identifying 40 studies reporting on 1573 effect sizes from 85 individuals. We synthesized effect sizes for treatment outcomes using a multi-level model to correct for multiple observations from the same individuals. The results showed significant treatment effects, with robust within-language treatment effects and …

Brief Relationship Support As A Selective Suicide Prevention Intervention: Piloting The Relationship Checkup In Veteran Couples With Relationship And Mental Health Concerns, Dev Crasta, Jennifer S. Funderburk, Tatiana D. Gray, James Cordova, Peter Britton

Psychology

Introduction: Close relationship problems play a key role in many contemporary theories of suicide. However, the potential of relationship support in suicide prevention is understudied. This study explores the feasibility, safety, acceptability, and promise of utilizing the 3-session Relationship Checkup (RC) in veterans with mental health and romantic relationship concerns. Methods: We conducted a single-arm pilot of telehealth RC in veterans with a positive mental health screen and their romantic partners. Couples completed baseline and post-treatment assessments of study outcomes. Results: Feasibility analyses showed we were able to recruit an elevated-risk sample (30% history of attempts or interrupted attempts), take …

Mind Matters : Vol 1, Issue 2 - 2023, Department Of Psychiatry

Department of Psychiatry Archives

• Message from the Chair
• Message from the Quality Improvement Representative
• Comprehensive Unit-Based Safety Program (CUSP)
• Empowering Multi-Disciplinary Care: Success Stories in Catatonia Management
• Impact of CARR Attributes Workshop
• Movements of Meeting for CUSP and Quality Initiatives: A Year Review
• Where Quality Begins: From Brainstorming to Brilliant Ideas, Every Thought Matters
• Educational sessions on International Patient Safety Goals
• From Approval: Key to Enhanced Quality and Effective Care
• Innovations and Improvements in Outpatient Psychiatric Services
• Improving Clinic Appointment Booking Capacity of Psychiatry Department
• Online Advanced Payment Module Enhances Patient Convenience …

Mind Matters : Vol 1, Issue 1 - 2023, Department Of Psychiatry

Department of Psychiatry Archives

• Message from the Chair
• Meet our Faculty Members
• Non-full-time Faculty Members
• Professor Emeritus
• Visiting Faculty
• Psychiatry Services
• Allied Services
• Occupational Therapists
• Outreach Services
• Education Activities / CME
• Conferences & Workshops
• Quality Improvement Initiatives
• PGME Activities/Achievements
• Meet Our Residents & Fellows
• UGME Activities
• Research Activities
• Key Achievements
• Upcoming Event
• Newsletter Editors

Comparison Of Self-Reported Depression And Anxiety Scores Between U.S. Households With And Without Children At Early And Later Stages Of The Covid-19 Pandemic, Hanan Mohammed Eissa Jamali

Electronic Theses and Dissertations

Parents in particular, are disproportionately affected by the 2019 coronavirus pandemic and the lockdowns that followed. Parents had to find a way to balance work, teaching, and taking care of their kids when schools were forced to close for safety reasons. While changes in parents' mental health have been the subject of a number of studies, there have been no studies comparing the level of depression and anxiety experienced by parents with and without children below the age of 18 years in the United States. Data for this study came from Households Pulse Survey (HPS) (week 2 N = 41,996; …

Health Monitoring From Home: Legal Considerations Of Wearable Technology In Telemedicine, Polina Declue

SMU Science and Technology Law Review

The COVID-19 pandemic created the necessity to access medical care from one’s home, giving rise to a new standard of healthcare through “telemedicine.” However, although efficient in many ways, the most significant limitation of telemedicine was the inability of doctors to monitor their patients’ conditions remotely. Wearable devices, also known as “wearables,” provide a way to bridge the gap. Over the last five years, wearables grew to be one of the fastest-growing industries in healthcare, seeing over $5 billion in growth. However, this also came with a myriad of legal concerns that may prevent wearables from being utilized efficiently. This …

Adaptive Learning Gain In Asset Pricing, Sedealy Juste Lokossou

Electronic Theses and Dissertations

This paper delves into the complexities of asset pricing, emphasizing the need to go beyond prevailing paradigms and constant learning gain assumptions. We examine the influence of personal experiences, adaptive learning processes, and subjective return expectations on asset pricing. By incorporating the concept of time-varying learning gain, we provide a more realistic portrayal of asset pricing. Empirical analysis reveals a consistent negative correlation between experienced real payout growth and subsequent returns, indicating counter-cyclical behavior. Our findings also support the mean-reversion hypothesis in stock returns, although caution is needed due to some scenarios lacking statistical significance. Theoretical exploration uncovers that higher …

Employee Monitoring: As Technology Advances Yet The Electronic Communications Privacy Act Stays In The Past, Isabela Possino

SMU Science and Technology Law Review

Since the Electronic Communications Privacy Act of 1986 was enacted, the United States has endured an evolution of technology. While progressive at its inception, the ECPA has since been met with a tumultuous response from scholars, courts, and others trying to understand its purpose and application regarding privacy rights and the monitoring of communications. Specifically, since the COVID-19 pandemic, the ECPA has remained at the forefront of debate with respect to employee monitoring and surveillance practices. This article provides an overview of the ECPA and explains why today’s technological advancements have surpassed the protections afforded by the Act, leaving employees …

Preventing Intimate Image Abuse Via Privacy-Preserving Credentials, Janet Zhang, Steven M. Bellovin

SMU Science and Technology Law Review

The problem of non-consensual pornography (“NCP”), sometimes known as intimate image abuse or revenge porn, is well known. Despite its distribution being illegal in most states, it remains a serious problem, if only because it is often difficult to prove who uploaded the pictures. Furthermore, the Federal statute commonly known as Section 230 generally protects Internet sites, such as PornHub, from liability for content created by their users; only the users are liable, not the sites.

One obvious countermeasure would be to require Internet sites to strongly authenticate their users, but this is not an easy problem to solve. Furthermore, …

Clinical Evaluation Of Gingival Healing Following Gingivectomy With Application Of Human Placental Extracts (Placentrex Gel), Rana M. Al Ashmawy, Ayman A. Elkashty, Mohammed M. El Shennawi

Mansoura Journal of Dentistry

Objective

To evaluate the adjunctive application of human placental extracts (placentrex gel) on the healing of gingival tissue after gingivectomy.

Materials and methods

The present study was made on twenty patients who were suffering from gingival enlargement and seeking for gingivectomy procedures. Ten patients were treated with gingivectomy with application of placentrex gel after surgery for a month as study group. The other ten patients were treated with gingivectomy without the application of placentrex gel after surgery as control group. Different clinical periodontal parameters were recorded including the scores of Plaque index, Postoperative pain index, Wound-Healing index and Degree of …

“With Friends Like These . . . .” Doctors And Nurses Criticizing Co-Employed Colleagues. Are These Criticisms Admissible As Vicarious Opposing Party’S Statements?, Marc D. Ginsberg

Saint Louis University Law Journal

Healthcare provider incivility includes non-collegial conduct such as physicians criticizing co-employed physicians when speaking with patients. This conduct is, obviously, disruptive, and does not help to establish productive, collegial, employee relationships.

Additionally, this incivility may have evidentiary consequences in medical/hospital negligence litigation. If the healthcare providers are employed by a hospital or other healthcare organization, the criticisms of co-employed colleagues which are communicated to patients may be admissible against the employer in medical/hospital negligence litigation as vicarious opposing party’s statements. This paper explores this evidentiary curiosity.

A New Tool In Police-Civilian Mediations: Conflict Coaching And Its Potential Benefits, Beatrice Connaghan

Saint Louis University Law Journal

Communities across the country have implemented mediation programs as an alternative dispute resolution process for civilian complaints against police officers. These programs vary from state to state, but certain challenges exist in each, such as ensuring neutrality, encouraging participants to engage fully in the mediation, and navigating subconscious biases held by officers and civilians. In response to these issues, this article considers whether conflict coaching opportunities within these programs have the potential to improve their effectiveness in resolving disputes and better support mediation participants. Conflict coaching is an emerging conflict navigation tool and thus there is limited research on its …

The Ethics Of Assisting Incarcerated People With Collective Action, Daniel J. Canon

Saint Louis University Law Journal

No abstract provided.

How Do You Teach Immoral Laws?, Nicole Hallett

Saint Louis University Law Journal

No abstract provided.

On Teaching Crimmigration Law, Philip L. Torrey

Saint Louis University Law Journal

No abstract provided.

Seeing The Supreme Court As A Whole Institution: Law And Social Science, Morgan L. W. Hazelton

Saint Louis University Law Journal

No abstract provided.

Moving Beyond The Basics Of The Ada And Section 504: Opportunities For Equitable And Inclusive Access To Law Libraries, Collections, And Services, Jessica De Perrio Wittman

Faculty Articles and Papers

No abstract provided.

Law's Credibility Problem, Julia Simon-Kerr

Faculty Articles and Papers

Credibility determinations often seal people's fates. They can determine outcomes at trial; they condition the provision of benefits, like social security; and they play an increasingly dispositive role in immigration proceedings. Yet there is no stable definition of credibility in the law. Courts and agencies diverge at the most basic definitional level in their use of the category.

Consider a real-world example. An immigration judge denies asylum despite the applicant's plausible and unrefuted account of persecution in their country of origin. The applicant appeals, pointing to the fact that Congress enacted a "rebuttable presumption of credibility" for asylum-seekers "on appeal." …

Reforming Prior Conviction Impeachment, Julia Simon-Kerr, Anna Roberts

Faculty Articles and Papers

No abstract provided.

Building My Professional Identity, The University Of Texas Rio Grande Valley. College Of Health Professions Student Success Team, Suad Ghaddar, Keri Gonzalez, Murat Karabulut, Amparo Jaramillo, Fidencio Mercado, Zelma D. Mata, Blanca Robles, Sonya Salinas, Manuel Zavala, Lin Wang

Open Educational Resources - Books

No abstract provided.

Engl 6360 - Descriptive Linguistics For Teachers, Ramsés Ortín

Open Educational Resources - Books

No abstract provided.

Student Handbook- 2023-2024, Student Activities Staff

Student Handbooks

Sudent handbook