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Impacts Of Covid-19 On Global Healthcare Management And Research, Stephanie Autore, Santanu De

Biology Faculty Articles

The Coronavirus Infectious Disease 2019 (COVID-19) pandemic has affected most nations at all levels of functioning, individual to governmental. Therefore, it is imperative to evaluate the effects the virus has had on one of the most important socioeconomic global sectors, healthcare. This literature review explores key, recent research and management strategies that have been undertaken in healthcare systems around the world in order to make meaningful attempts at identifying the etiology, diagnosis, and treatment of the disease, and combating the spread of this deadly virus. Healthcare facilities have implemented a variety of changes, all geared towards reducing non-emergency patient visits …

Mechanisms And Consequences Of Cross-Generational Acclimatization In Reef-Building Corals, Kevin Harrison Wong

Open Access Dissertations

Coral reefs are valued over trillions of dollars and are becoming increasingly degraded due to global climate change. Ocean warming disrupts the symbiotic relationship between corals and their algal symbiont, Symbiodinaceae, leading to severe energetic reduction and increased mortality. Recent studies have identified the potential for beneficial within-generational and cross-generational acclimatization to mitigate the impacts of future environmental change, however the mechanisms and outcomes remain understudied in tropical corals. Here, I present three manuscripts testing different mechanisms of within- and cross-generational acclimatization in corals to understand the long-term consequences of ocean warming. First, we tested the hypothesis that the survival …

มาตรการทางกฎหมายในการคุ้มครองสิทธิของผู้บริโภคจากผลิตภัณฑ์อาหารที่มีโซเดียมสูง, ชนิสร เจียมเจือจันทร์

Chulalongkorn University Theses and Dissertations (Chula ETD)

วิจัยนี้มีวัตถุประสงค์เพื่อศึกษาแนวคิดพื้นฐานและความเป็นมาของการคุ้มครองผู้บริโภคในการได้รับข้อมูลข่าวสารและความปลอดภัย รวมถึงมาตรการในการคุ้มครองสิทธิของผู้บริโภคจากผลิตภัณฑ์อาหารที่มีโซเดียมสูงของประเทศไทย ทั้งตาม พระราชบัญญัติคุ้มครองผู้บริโภค พ.ศ. 2522 พระราชบัญญัติอาหาร พ.ศ. 2522 และประกาศกระทรวงสาธารณสุข เปรียบเทียบกับมาตรการของต่างประเทศ ได้แก่ ประเทศชิลี ประเทศสหราชอาณาจักร และประเทศสหรัฐอเมริกา เพื่อใช้เป็นแนวทางในการวิเคราะห์ปัญหาที่เกี่ยวข้องกับการคุ้มครองสิทธิของผู้บริโภคจากผลิตภัณฑ์อาหารที่มีโซเดียมสูงตามกฎหมายไทย และสามารถเสนอแนวทางแก้ไขปัญหาการคุ้มครองสิทธิของผู้บริโภคได้อย่างเหมาะสม ทั้งนี้จากการวิจัยพบว่า สิทธิที่จะได้รับข้อมูลข่าวสารและความปลอดภัยเป็นสิทธิขั้นพื้นฐานที่ผู้บริโภคควรจะได้รับจากการบริโภคผลิตภัณฑ์อาหาร และเป็นหนึ่งในสิทธิมนุษยชนที่ภาครัฐเข้ามามีบทบาทในการป้องกันอันตรายที่มีต่อความปลอดภัยและสุขภาพของผู้บริโภค ซึ่งจากการศึกษามาตรการฉลากโภชนาการและมาตรการปรับสูตรในภาคอุตสาหกรรมของประเทศไทยและต่างประเทศพบว่า มาตรการของประเทศไทยยังไม่เหมาะสมเท่าที่ควรที่จะคุ้มครองสิทธิของผู้บริโภคในการได้รับข้อมูลข่าวสารและความปลอดภัยจากผลิตภัณฑ์อาหารที่มีโซเดียมสูงได้อย่างครอบคลุม ทั้งมาตรการทางฉลากโภชนาการ ในเรื่องรูปแบบฉลากโภชนาการ ขอบเขตของผลิตภัณฑ์ที่ใช้บังคับ และมาตรการปรับสูตรในภาคอุตสาหกรรม ในเรื่องรูปแบบการใช้บังคับ รวมไปถึงมาตรการอื่นที่นำมาใช้ร่วมกับมาตรการปรับสูตรในภาคอุตสาหกรรม ผู้เขียนจึงเสนอให้แก้ไขเพิ่มเติมประกาศกระทรวงสาธารณสุขและออกมาตรการอื่นเพิ่มเติม เพื่อคุ้มครองสิทธิของผู้บริโภค ตลอดจนสิทธิผู้ป่วยได้อย่างครอบคลุม

Development Of An Extraction Method Of Mucuna Pruriens Seeds For A Chemically And Physically Stable Extract, Chayarit Vilairat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Levodopa (L-DOPA) is a drug for the treatment of Parkinson's disease (PD). Currently, it derives from chemical synthesis and plants, especially Mucuna Pruriens (MP) seeds. The results of clinical studies found using the L-DOPA-containing MP for the treatment of PD could reduce side effects more than the synthetic one but patients must take MP powder in high amounts per a single dose which may cause inconvenience. Therefore, using the extract can help in the reduction of the dose. Unfortunately, the water extract from the MP seeds can be easily degraded physically and chemically; especially the physical appearance e.g., darkening color, …

Production And Biological Activities Of Oligo Pectin From Early Immature Fruit Of Durio Zibethinus L., Aunchiya Pitaksa

Chulalongkorn University Theses and Dissertations (Chula ETD)

Early immature durian (EID) fruits, 30-45 days after anthesis with 6-12 cm in length, are considered agricultural waste from cultivation. It is known that durian rinds of mature fruits contain pectin, but there have been no reports on the pectin content of early immature durian (EID) fruits. Therefore, the objective of this study was to determine the pectin content in EID fruits. We extracted pectin from EID fruits using distilled water at different temperatures (25°C, 50°C, and 75°C) for 1 h to investigate pectin content. Instrumental analyses, including X-ray diffraction (XRD) and Fourier Transform Infrared Spectrometer (FT-IR), confirmed the presence …

Anti-Neuroinflammatory Effects Of Auricularia Polytricha Extracts On Bisphenol A (Bpa)-Induced Microglial Cell Activation And Reduction Of Hippocampal Cell Damage, Chanin Sillapachaiyaporn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Bisphenol A (BPA) is widely used in the production of polycarbonate plastics, it has been reported that BPA can activate neuroinflammation. Neuroinflammation is a brain pathology that involves the high levels of pro-inflammatory mediators, including tumor necrosis factor-alpha (TNF-α). An excessive TNF-α expression could result in neuronal cell death and subsequently lead to neurodegeneration. Auricularia polytricha (AP) is an edible mushroom with several medicinal properties. Herein, the anti-neuroinflammatory effects of AP extracts against BPA-induced BV2 microglial inflammation were investigated. Hexane (APH) and ethanol (APE) extracts of AP inhibited BPA-induced neuroinflammation in BV2 cells by reducing the expression of pro-inflammatory cytokines. …

Take It With A Grain (Or More) Of Salt: Why Industry-Backed Dietary Guidelines Fail Americans And How To Fix Them, Caroline Farrington

University of Michigan Journal of Law Reform

The U.S. Dietary Guidelines lack oversight and accountability. The result: Guidelines that reflect food industry interests instead of modern science. This deleterious guidance goes on to govern federally-subsidized food assistance programs and to influence dietary choices throughout the private sector and private life. Ultimately, the Guidelines significantly contribute to the endemic chronic disease they seek to address.

The Guidelines Advisory Committee is notoriously rife with conflicts of interest, and thus most Guidelines scholarship has focused on reforming the Committee. But the 2015 and 2020 Guidelines show that these reforms are insufficient and agency-level change is necessary. In 2015, the Committee …

Project H.O.M.E: A Novel Nature-Based Therapy Approach For The Treatment Of Veterans With Trauma, Jenny L. Laverdure

Psychology Doctoral Specialization Projects

Around the world, trauma disorders such as post-traumatic stress disorder (PTSD) are on the rise. Evidence-based treatment protocols, such as cognitive processing therapy (CPT) and prolonged exposure (PE) are effective in treatment. However, high dropout rates, stigma, and other barriers to treatment are driving the exploration of alternative treatment options. Nature-based interventions, such as wilderness or adventure therapy, forest bathing, and horticulture therapy, have been utilized for a variety of medical and psychological disorders for several years. There are limited formal programs, but research generally supports positive outcomes with specified interventions. However, there are several challenges to studying the effectiveness …

The Secret Life Of Staghorn Ferns: Social Organization And Labor Division In A Eusocial Plant, Isabelle Small

The Synapse: Intercollegiate science magazine

No abstract provided.

Magical Mushrooms: The Role Of Fungi In Our Past And Future, Ella Erdahl

The Synapse: Intercollegiate science magazine

No abstract provided.

The Regulation Of Stress Steroid Release In Freshwater Turtles, Yoke Tassent

Honors Program Theses

The goal of this study is to characterize the Hypothalamic-Pituitary-Adrenal (HPA) axis regulators of the stress response in a turtle species, the Red-Eared slider, Trachemys scripta elegans and to determine if NPY acts as a secretagogue for adrenal steroids in reptilian species, as it does in mammals. Here, I caught turtles using baited hoop traps. Then, I used pharmacological injections of ACTH (intermediate in HPA axis), dexamethasone (DEX, a synthetic steroid that blocks ACTH release and induces HPA negative feedback), NPY (starvation hormone), and NPY receptor agonists. Each turtle received a single injection upon capture, and I recorded whether adrenal …

Synthesis And Evaluation Of Novel Tyrosinase Inhibitors, Virginia Bailey

Honors Program Theses

Melanin is responsible for the protection against ultraviolet light and the pigmentation of mammalian skin, hair, and eyes.1–3 This indolic polymer is located in the epidermis of mammals and is produced through melanogenesis in specialized cells called melanocytes. Over production of melanin in humans can produce unwanted aesthetic products such as dark spots, freckles, solar lentigo (age spots), melasma, and even cancer.2,4,5 The overproduction of melanin during post-harvest handling causes enzymatic browning of produce resulting in a loss of nutritional value, a decrease in shelf life, and a decline flavor.2,6–8 Tyrosinase is an oxidoreductase, type-3, copper-containing glycoprotein located in the …

Decarceration Means Funding The Incarcerated, David Campbell

City University of New York Law Review

While there are varied assertions as to what “defunding the police” and “reinvesting in communities” mean, I propose that one step towards this goal would be to redistribute the funds from Corrections Offices and bureaucratic management to incarcerated workers to ensure they are paid a suitable wage. If an increase in inmate pay appears outrageous to some, it is only because it entails beginning to treat inmates as full-fledged human beings and, in doing so, upsets the power dynamic between the incarcerated and their keepers.

Association Of Diet Qualitymeasured By Three A Priori-Defined Dietary Patterns With Gut Microbiota And Intestinal Permeability Among Obese Individuals, Sarah Eaton, Heather Rasmussen, Weiwen Chai

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: The human gastrointestinal tract (GI)may play a critical role in the prevention of obesity and metabolic diseases. Considering the importance of a healthy diet for optimal health, this study examined associations of diet quality assessed by three a priori-defined dietary patterns (Healthy Eating Index 2010 [HEI-2010],Mediterranean Eating Pattern for Americans [MEPA], and Dietary Approaches to Stop Hypertension [DASH] with gut microbiota, short-chain fatty acids (SCFA) and intestinal permeabilitymarkers in adult obese participants.

Conclusions: Blautia abundance and inversely associated with intestinal permeability markers such as urinary 24-h sucralose levels suggesting diet quality may have positive impact on the human GI …

Intracellular Fate Of Bovine Milk Exosomes In Murine Bone Marrow-Derived Macrophages, Afsana Khanam, Janos Zempleni

Department of Nutrition and Health Sciences: Faculty Publications

Milk exosomes (MEs) and their microRNA cargos constitute novel bioactive food compounds, and bovine MEs (BMEs) are being considered for use in drug delivery. The internalization of MEs by macrophages and degradation in lysosomes (in all cells) limit biological activities. Here, we determined whether BMEs internalized by murine bone marrow-derived macrophages (BMDMs) retrofuse with the intralumenal membrane in the multivesicular body (MVB) for subsequent release into the extracellular space or whether BMEs are destined for degradation in lysosomes.

Conclusions: The retrofusion of BME-derived intralumenal MVBs and secretion of BME into the extracellular space is quantitatively minor in BMDMs. The majority …

Genetically Altered Bovine Milk Exosomes (Bmes) Evade Elimination Bymurine Bone Marrow-Derived Macrophages (Bmdms), Alice Ngu, Janos Zempleni

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: To develop BMEs that evade elimination by BMDMs.

Conclusions: The elimination of BMEs UNL1 and UNL2 is significantly reduced compared unmodified BMEs in BMDM cultures. This is of great importance when using BMEs for delivering therapeutics.

Factors Associated With Accidental Drug Exposure In U.S. Adults Over 65 Years Of Age, Edwin Raj

Walden Dissertations and Doctoral Studies

Medication errors are a major public health issue and a leading cause of fatalities in the United States and globally. Older adults who rely on medications to address age-related health issues are at higher risk of medication errors. Accidental exposure to drugs is a major type of medication error that impacts older people more than other age groups. The purpose of this quantitative correlational study was to examine the association between patient gender, age group, and reporter type and accidental exposure to drugs in older people. The ecological model was used to guide the study. Logistic regression analysis was used …

Rising Cost Of Medicare And Its Effect On Recipients 65 And Older, Williesa Toomer

Walden Dissertations and Doctoral Studies

The rising cost of Medicare is a growing concern for recipients. Beneficiaries are often forced to implement a host of strategies to meet rising out-of-pocket expenses. This qualitative study was conducted to address a research gap in methods used by senior citizens to manage rising Medicare coverage costs. Garmezy’s resilience theory was used to contextualize the rising costs of Medicare premiums and copays and strategies used to manage healthcare needs. The purposive sample of 12 socioeconomically diverse respondents included eight women and four men ranging in age between 65 and 77, for an average age of 70.2 years. Participants completed …

Improving Advance Care Planning Among Native Americans, Jasjit Kaur Pataria

Walden Dissertations and Doctoral Studies

A staff education project was created in a tribal health system of primary care clinics to improve advance care planning (ACP) conversations between care providers and Native American tribal patients. ACP conversations and advance directive documentation occurrences were found to be low or negligible in the project site despite primary care clinics being an ideal place to start these conversations. The purpose of the staff education project was to improve the knowledge and attitudes of providers toward initiating ACP conversations in a rural underserved community of Native Americans. The knowledge-to-action model was used to frame the project. Pretests and posttests …

Influence Of Landscape Attributes On Virginia Opossum Density, David A. Bernasconi, Wesley C. Dixon, Matthew T. Hamilton, James L. Helton, Richard B. Chipman, Amy T. Gilbert, James C. Beasley, Olin E. Rhodes Jr., Guha Dharmarajan

United States Department of Agriculture Wildlife Services: Staff Publications

TheVirginia opossum (Didelphis virginiana), North America's only marsupial, has a range extending from southern Ontario, Canada, to the Yucatan Peninsula, Mexico, and from the Atlantic seaboard to the Pacific. Despite the Virginia opossum's taxonomic uniqueness in relation to other mammals in North America and rapidly expanding distribution, its ecology remains relatively understudied. Our poor understanding of the ecology of this important mesopredator is especially pronounced in the rural southeastern United States. Our goal was to estimate effects of habitat on opossum density within an extensive multiyear spatial capture‐recapture study. Additionally, we compared the results of this spatial capture‐recapture …

Tooth Agenesis, Thomas Labarias

Graduate Student Dissertations, Theses, Capstones, and Portfolios

In this literature review, I will discuss tooth agenesis, which is a congenital absence of one tooth or more, and the terminology associated. I will then discuss and compare the studies regarding the etiology and the prevalences of tooth agenesis throughout the world population. The second half of the paper will cover tooth agenesis from a clinical standpoint. I will describe the capital different complications and phenotypes that tooth agenesis creates. In the last section, I will explain how tooth agenesis is medically treated, and the multidisciplinary management needed to improve the patient’s quality of life.

Covid-19 In Sub-Saharan Africa: Monitoring Impacts On Learning Outcomes: Kenya Report, Australian Council For Educational Research (Acer), Unesco Institute For Statistics

Monitoring Learning

Six African countries participated in the COVID-19: Monitoring Impacts on Learning Outcomes (MILO) project in 2021 – Burundi, Burkina Faso, Côte d’Ivoire, Kenya, Senegal and Zambia. This report presents the key findings from the MILO project for Kenya. The MILO study was designed to provide information on the impact of the pandemic on learning outcomes. As countries work towards achieving Sustainable Development Goal (SDG) 4.1.1b, it is essential that progress towards this goal continues to be monitored. The MILO project was implemented to provide a way for countries to measure learning progress against Sustainable Development Goal (SDG) 4.1.1b prior to, …

Associations Between Handgrip Strength Asymmetry And Health Related Quality Of Life Among Canadian Adults: An Analysis Of The Canadian Health Measures Survey, Jessica Lembke

Theses and Dissertations

Background: Health related quality of life (HRQOL), a measure of perceived quality of health is significantly related to current and future health. Handgrip strength (HGS) asymmetry is an aspect of muscle function that can be measured using handheld dynamometry. While several studies have examined relationships between HGS asymmetry and HRQOL, few have used nationally-representative data, and none have used Canadian data. The aim of this study, therefore, was to examine the association between HGS asymmetry and HRQOL in a nationally-representative sample of Canadian adults.

Methods: A secondary analysis of cross-sectional data from cycles 5 and 6 (2016–17 and 2018–19) of …

Thermal Stability And Decomposition Of Per- And Polyfluoroalkyl Substances (Pfas) Using Granular Activated Carbon And Other Porous Materials, Pavankumar Challa Sasi

Theses and Dissertations

Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals that have been produced for decades as either processing aids or individual ingredients in many industrial and commercial products, including aqueous film-forming foams (AFFFs), non-stick cookware, and fast-food packaging. PFOA and PFOS have been reported in >95% of blood samples collected during multiple U.S. national surveys at concentrations that are a risk to human health. Thermal treatment is routinely used to reactivate the spent granular activated carbon (GAC) from water purification facilities. The aims of this study were: (1) to improve our understanding of the thermal stability of per- and polyfluoroalkyl substances; …

Juvenile Temperature Regulation In Apis Mellifera (Honey Bee) And The Impacts Of Brood Temperature Requirements On The Colony, Scott Debnam

Graduate Student Theses, Dissertations, & Professional Papers

Little is known about the energetic costs to insects of raising young. Honey bees collectively raise young, or brood, through a series of complex behaviors that appear to accelerate and synchronize the timing of brood maturation. These include maintaining the brood nest at warmer and consistent temperatures and the exceptional activity of "heater bees." The temperature at which juvenile insects are raised can profoundly affect their development. Apis mellifera (Honey bees) cope with temperature-dependent development via social behavior that maintains the relatively high and constant temperatures within the nest where the brood are raised. Yet juvenile honey bee development is …

Effectiveness Of General Practitioner-Delivered Nutrition Care Interventions On Dietary And Health Outcomes In Adults With Diet-Related Chronic Conditions: A Systematic Review Protocol, Kathryn E. Asher, Mari Somerville, Shelley Doucet, Alison Luke, Lauren Ball, Stephan U. Dombrowski, Mary Hickson, Richelle Witherspoon

School of Health Professions

Objective: This systematic review will evaluate the effectiveness of nutrition care interventions delivered by general practitioners (GPs) versus usual care or no care on dietary and health outcomes in adults with diet-related chronic conditions or risk states. Introduction: GPs are usually the first contacts for patients with diet-related chronic conditions in the healthcare system. While there is some evidence that GPs can be effective in delivering nutrition care for a number of outcomes, an update to the evidence is required as well as an examination of which components are associated with positive outcomes in order to inform future care. Inclusion …

Contributions Of Agroforestry Systems To Food Provisioning Of Peasant Households: Conflicts And Synergies In Chiapas, Mexico, Lorena Soto-Pinto, Sandra Escobar Colmenares, Marina Benítez Kanter, Angelita López Cruz, Erin Estrada Lugo, Balente Herrera Hernández, Estelí Jiménez-Soto

School of Geosciences Faculty and Staff Publications

Traditional agroforestry systems are widely recognized for their contributions to provisioning, support, regulation, and cultural services. However, because of the advancement of industrial agriculture and a corporative food system, peasants' food systems are rapidly undergoing transformation. We identify the contributions of four types of agroforestry systems (AFS)—shade cocoa agroforest, shade coffee agroforest, milpas and homegardens—to food provisioning in peasant families and discuss conflicts between traditional food systems and the contemporary industrial model of production and consumption confronted by peasants and semi-proletarian migrants. We carried out research in 17 peasant communities in Chiapas, Mexico, and conducted 97 semi-structured interviews and agroecological …

Implementing A Faith-Based Weight Loss Outreach Program For The Westside Community Of Jacksonville, Florida, Jonathan Peinado

Doctor of Ministry Projects

Problem

Jacksonville, Florida’s adult population has an obesity rate of 65.4% which is slightly lower than both regional and national averages (66.1%) but higher than the state average (63.2%).

Method

A faith-based weight loss program was developed for the residents of the west side of Jacksonville. The intervention incorporated behavioral, spiritual, and psychological modules. The program lasted a total of 10 weeks from beginning to end, with the main segment taking place over a 40-day (6-week) period. Participants underwent two biometric screenings, one at the beginning of the program and one at the end. They had daily health challenges such …

Inverse Association Between Yogurt Consumption And Metabolic Syndrome Prevalence In United States Adult Males, But Not In Females Or In The Total Population: Nhanes 2017-2018, Diana K. Lee

Master's Theses

Metabolic syndrome (MetS) is prevalent in the United States (US) population andconcerns lie in related chronic diseases and financial burdens. To mitigate MetS, modifying the diet is a possible solution. Yogurt is known for its nutrient density and is a possible health food. The growing interests in yogurt and the growing concerns for MetS are met with the gap of unraveling the yogurt consumption status and MetS prevalence in the US. We evaluated the association between yogurt consumption and MetS using the National Health and Nutrition Examination Survey (NHANES) 2017-2018 and Food and Nutrient Database for Dietary Studies data. The …

No Association Between Macronutrient Intake And Body Composition Indices In Collegiate Athletes, Bryan Singharaj

Master's Theses

A scarcity of literature follows the relationship between macronutrient intake and bodycomposition indices within an athletic population. Therefore, the primary aims of the present study were to evaluate the relationship between the percent intake of carbohydrates, dietary fat, and protein with fat-free mass percentage (FFM %), fat mass percentage (FM %), fat mass index (FMI), and lean mass index (LMI). In addition, a secondary objective was to determine if there were any sex differences in the relationship between macronutrient intake and body composition indices. A total of 58 San José State University student-athletes from multiple sports were included in the …