Digital Commons Network^™

Incidence Of Cancer, Depression, And Economic Burden Of Prescription Nsaids Among Older Adults With Osteoarthritis: Statistical And Machine Learning Approaches, Nazneen Fatima Mohammed Umer Shaikh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding the role of chronic inflammation among older adults is critical because of its implications on chronic inflammatory conditions as well as its interaction with anti-inflammatory medications. Osteoarthritis (OA) is a heterogeneous multi-faceted joint disease with multi-tissue involvement of varying severity, and increasing evidence demonstrates a key role of chronic inflammation in its pathogenesis. Approximately 30 million adults in the United States have OA, and it is reported that a large proportion (43%) of them are older than 65 years. OA is typically treated using non-steroidal anti-inflammatory drugs (NSAIDs) for minimizing pain and reducing inflammation. NSAIDs have consistently shown clinically …

Development Of A Transition Program For Young Adults With Type 1 Diabetes Progressing From Pediatric To Adult Care – A Feasibility Study, Elizabeth Ann Minchau

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Development of a Transition Program for Young Adults with Type 1 Diabetes Progressing from Pediatric to Adult Care – A Feasibility Study

Elizabeth A. Minchau

Background: Emerging adulthood requires a delicate balance of the competing social, educational, occupational, and financial demands typical of this developmental stage. This time period presents special challenges for adolescents with type 1 diabetes (T1D), who must also prioritize consistent medical follow-up and ongoing intensive self-care. Emerging adults with T1D struggle with glycemic control that is further exacerbated by an often-times disorganized transfer of care between pediatric and adult endocrinology practices. Substantial gaps in care …

Genetic Underpinnings Of Novel Trait Development In A Euwallacea-Fusarium Mutualism, Elaina J. Spahr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Evolutionary Developmental Biology seeks to answer fundamental questions about the mechanisms underlying the evolution and innovation towards increasing structural complexity within the body plan. The ambrosia symbiosis, a polyphyletic group of xylem-feeding beetles, provides a wealth of diversity in novel pouch-like structures called mycangia. This diversity could serve as a rich model for understanding how mutualisms may prompt structural innovation and diversification in a host organism. The ambrosia symbiosis has become a fast-growing research subject in entomology and forest pathology but has yet to experience the same attention under the lens of evolutionary developmental genetics.

Development of mycangia was examined …

Screen Media Use Among Children And Adolescents – Applications Of Supervised And Unsupervised Machine Learning And Sentiment Analysis, Yifan Zhang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Screen media has become increasingly pervasive in our everyday lives and has profoundly changed the way people communicate and interact with each other. However, we are still unclear about the long-term influence of screen media use on our physical health, mental health, and social wellbeing. Children and adolescents are in an important stage of brain development and are susceptible to the environmental influence that screen media possess. This dissertation pursued three aims to address research gaps related to screen media use among children and adolescents: 1) identify topics and knowledge gaps in screen media use research among children and adolescents …

States' Public Health Funding And Population Health Outcomes: An Examination Through A Socio-Ecological Lens, Maureen K. Akubu-Odero

College of Graduate Studies: Theses & Dissertations

The US public health system has been underfunded for decades, despite its significant mandate of improving overall population health outcomes. This ecological study evaluates the association between state public health funding and population health outcomes and the role of state public health funding in reducing state-level health disparities. The findings show that the relationships between public health investments and improvements in health outcomes and health disparity in states are moderated by socioeconomic contextual factors. The findings suggest a need for continued and increased public health investments, tailored to community needs and context

2021-2022 Georgia Southern University Women's Basketball Roster, Georgia Southern University

Women's Basketball Records

• 2021-22 Women's Basketball Roster

Practices Of Vitamin D Supplementation Leading To Vitamin D Toxicity: Experience From A Low-Middle Income Country, Siraj Muneer, Imran Siddiqui, Hafsa Majid, Nawazish Zehra, Lena Jafri, Aysha Habib

Department of Pathology and Laboratory Medicine

Introduction: The trend of prescribing VD preparations for nonspecific body aches and self-medication has increased significantly. The importance of vitamin D toxicity (VDT) has been underestimated and under recognized. This study was done to determine the frequency toxicity (>150 ng/ml) in subjects for 25-hydroxyvitamin D (25OHD) and evaluate the vitamin D (VD) supplements used by these subjects.
Methodology: This descriptive cross-sectional study was conducted at the Section of Chemical Pathology, Aga Khan University Hospital Karachi from April 2020 to March 2021. Subjects with 25OHD toxicity were contacted and information related to history of calcium and VD supplementation were collected. …

Who's Included? A Systematic Review Of Socio-Demographics And Participant Recruitment Within The Investigation Of Periodontal Disease And Its Treatment Effect On Hemoglobin A1c, Jaclyn L. Johnson

All Master's Theses

Diabetes mellitus and periodontal disease are major global public health concerns. Within the United States (U.S.) over 34 million adults have diagnosed diabetes (Centers for Disease Control and Prevention [CDC], 2020a), and 64 million U.S. adults have periodontitis (American Academy of Periodontology [AAP], 2021a). Research has shown that persons with diabetes have a coinfection with periodontal disease at a rate between 2.6 and 2.9 times higher than persons without diabetes (Wang et al., 2014). Diabetes and periodontal disease collectively and disproportionately affect persons of low socioeconomic status (SES), age, and particular racial/ethnic identities (AAP, n.d.b; CDC, 2021; Connolly et al., …

Investigating The Effects Of Body Weight Fluctuations On Insulin Resistance In Adults: A Nhanes Study, Jessica Claire Burke

All Master's Theses

The aim of this study was to investigate the effects of a history of weight cycling on insulin resistance (IR) utilizing the 2015-2020 NHANES database. A value greater than 3.2 for homeostatic model assessment of insulin resistance (HOMA-IR) was used to define IR. No study to date has examined the weight cycling question since its application in the NHANES 2015-2016 cycle year. RESULTS 53% of the total 4100 participants reported weight cycling at least once and 33% of the total were classified as having IR. Prevalence of IR and obesity were highest amongst those who weight cycled 3 times or …

Associations Between Atherogenic Markers And Hearing Loss: National Health And Nutrition Examination Survey: 2011-2012, 2015-2016, Anna Anya Rombakh

All Master's Theses

Importance Hearing loss (HL) is a major public health problem that has been previously found to be associated with abnormal atherogenic markers.

Objective To investigate the associations between such atherogenic markers and the degree of HL using continuous NHANES data from cycle years 2011-2012 and 2015-2016.

Design, Study, and Participants This observational study used data from two National Health and Nutrition Examination Survey (NHANES) cycle years 2011-2012 and 2015-2016. NHANES continuously conducts data collection via home interviews and physical exams completed in their Mobile Examination Centers. NHANES participants ages 20-69 who partook in audiometry, anthropometric and laboratory testing were included. …

Factors Influencing Intestinal Parasite In Black-And-White Ruffed Lemurs (Varecia Variegata), Eliette Noromalala

All Master's Theses

Ecological factors, such as feeding behavior and climatic seasonality, might influence intestinal parasite infection and patterns in non-human primates. Here, we examined if frugivory levels and climate (i.e., temperature and rainfall) were associated with parasite patterns in black-and-white ruffed lemurs (Varecia variegata). Feeding data using 5-min focal sampling, climate data, and fecal samples from V. variegata (n = 23) at the “Mangevo” site were collected from February through May 2019. Microscopic examinations of fecal flotation and sedimentation were done to identify and count parasites. Nematoda (Callistoura vauceli, and Strongyloides sp.) Ciliophora (Balantidium sp.), Coccidia ( …

Development Of Novel Pyridazine Derivatives And Drug Delivery Systems Against Dengue, Janae A. Culmer

College of Graduate Studies: Theses & Dissertations

The lack of approved vaccines, medications and treatment regimens has significantly contributed to the rapid spread of mosquito-borne viruses such as Dengue and Zika virus. The complex immunopathology of these viruses presents limitations for the development and implementation of a definitive, safe and effective approach to combat infections.Previous research has demonstrated that vector control strategies such as the elimination of larval habitats, larviciding with insecticides, the use of biological agents and the application of adulticides have been unsuccessful in the reduction of viral transmission leading to the need for the continued development of antivirals. This research proposes an approach for …

Effects Of Unpaved Roads On Relative Abundance And Epigenetics Of Early Successional Lizards, David Tevs

College of Graduate Studies: Theses & Dissertations

Unpaved roads may provide uniform microhabitat characteristics and impart edge effects in the adjacent landscape that mediate environmental pressures acting on small vertebrates. These features may allow species that are associated with recent disturbance to persist in aging forest patches. Further, epigenetic mechanisms such as DNA methylation may provide these species the phenotypic plasticity necessary to occupy multiple habitats with different environmental conditions. To understand how small vertebrates use unpaved roads, the relative abundance and occurrence of Florida scrub lizards (Sceloporus woodi) and six-lined racerunners (Aspidoscelis sexlineata) were quantified using visual encounter surveys along unpaved roads …

Implied Warranties V. Express Specifications Under The Uniform Commercial Code, David S. Coale, Michael P. Lynn

Oklahoma Law Review

No abstract provided.

Reducing Administrative Burdens To Protect Taxpayer Rights, Leslie Book, T. Keith Fogg, Nina E. Olson

Oklahoma Law Review

No abstract provided.

Calculating “Income” For Domestic Support Obligations In The Wake Of The Covid-19 Pandemic, Kimberly S. Krieg, Stephanie L. Tang

Oklahoma Law Review

No abstract provided.

A Contraction Based Approach To Tensor Isomorphism, Anh Kieu

Honors Theses

Tensor isomorphism is a hard problem in computational complexity theory. Tensor isomorphism arises not just in mathematics, but also in other applied fields like Machine Learning, Cryptography, and Quantum Information Theory (QIT). In this thesis, we develop a new approach to testing (non)-isomorphism of tensors that uses local information from "contractions" of a tensor to detect differences in global structures. Specifically, we use projective geometry and tensor contractions to create a labelling data structure for a given tensor, which can be used to compare and distinguish tensors. This contraction labelling isomorphism test is quite general, and its practical potential remains …

The Fifth Vital Sign: An Anthropological Analysis Of Productive And Unproductive Pain, Kathleen Meerscheidt

Honors Theses

Throughout my time as a Division I rower, I have struggled to understand the ways that I understand my own normalization of pain within a broader cultural environment that portrays pain as a mostly negative aspect of life. This moral quandary inspired me to start researching the role of pain in different socio-cultural contexts. For my thesis, I conducted original research, in the form of participant observation and semi-structured interviews, to build on what I found through an extensive literature review. First, I looked at the ways in which pain is understood within Western biomedicine and, subsequently, “Western” culture. Within …

Nurses’ Perceptions Of Their Role Utilizing Eat, Sleep, Console, In The Management Of Neonatal Abstinence Syndrome, Cerys Eldred

Honors Theses and Capstones

Background: There is a rising prominence of infants being born and diagnosed with Neonatal Abstinence Syndrome (NAS) in the United States. In recent years, a new non-pharmacological method of managing these infants called Eat, Sleep, Console (ESC) has emerged. While there is mounting evidence demonstrating the positive outcomes for infants treated with this method, there is limited research regarding nurses’ perceptions of this new intervention. This study seeks to understand the nurse’s experience and role during caring for infants with NAS utilizing the ESC method in comparison to the past practices.

Methods: This study used a qualitative descriptive design to …

Does Pesticide Regulation Impact The Export Competitiveness Of Major Global Cocoa Producers?, Olaide Akin-Olagunju, Abiodun Falusi, Sulaiman Yusuf, Victor Okoruwa

Journal of African Trade

Abstract Several methods are used to evaluate competitiveness, but the non-inclusion of quality measures, despite their importance in international product markets, gives less credence to such assessments. This study evaluates export competitiveness in the cocoa sector from the context of pesticide regulations. Such regulations are now increasingly common, due to their perceived benefits for humans, animals, and the environment. The results of our study show that cocoa-exporting countries stand to derive more earnings if standards are harmonized at the Codex level. Adherence to international standards, as reflected in large standard-scaled trade values, enhances competitiveness: yet compliance capacity must be matched …

The Effect Of Administration Of Siamese Catfish (Pangasius Hypophthalmus) Extract On Fibroblast Cells After Tooth Extraction In Wistar Rats, Veny Larasati, Trisnawaty, Angelina N. Ricardo

Journal of Dentomaxillofacial Science

No abstract provided.

Comparison Of The Different Isoforms Of Vitamin E Against Amyloid Beta-Induced Neurodegeneration, Alp Yi̇ği̇t Özdemi̇r, Esi̇n Çeti̇n, Mehmet Ali̇ Onur

Turkish Journal of Biology

Neurodegeneration is the progressive loss of structure or function of neurons. Amyloid beta oligomers and aggregates have been linked to neurodegeneration. While previous studies have suggested that dietary α-tocopherol intake can prevent amyloid beta aggregation and protect the brain against neurotoxicity, other research, however, indicated that tocotrienol forms might be used as an alternate agent against this kind of degeneration. In the presented research, we compared the in vitro protective effects of α-tocopherol and α-tocotrienol. In this context, we formed an in vitro neurodegeneration model with primary isolated neurons and measured α-tocopherol's and α-tocotrienol's protective effects. As a result, α-tocopherol …

A Relational Understanding Of Human Rights: Human Dignity In Social Solidarity, David Hollenbach

Emory Law Journal

No abstract provided.

Higher Education And Food Access: A Case Study Of Food Access Initiatives And Their Community Impact, Rebecca Wheaton

All Master's Theses

Food security issues are being prioritized across college campuses and among student communities in the wake of the COVID-19 pandemic. While basic needs services are typically available on campuses, there is still a discrepancy between availability and accessibility. Ellensburg, Washington, has vulnerable food-insecure populations, including Central Washington University (CWU) students, whose access issues involve not only social, cultural, and political dimensions, but also practical considerations like transportation, distance to grocery stores, and affordability of food resources. A central concern of this research is to understand food as constitutive of different forms of symbolic, cultural, and economic capital following Bourdieu’s Theory …

An Extreme Preterm Infant With Multiple Complications: A Case Study, Yashoda Sathish

Manipal Journal of Nursing and Health Sciences

Extreme preterm birth is the most critical risk factor, which leads to adverse effects on medical and developmental outcomes. We report a case of an extremely preterm infant admitted to NICU and had a prolonged period of non-invasive ventilation. The neonate had hepatosplenomegaly and antibiotic, antifungal, and antiviral treatment. She was recovered and shown significant improvement in her health status and growth and development were assessed until five years of corrected age.

Annual Report Of The President, Memphis State University, 1986-1987

Other Publications

1986-1987 Annual Report of the President.

Interoception Toolkit: A Resource For Occupational Therapy Practitioners To Use With Children And Their Families, Heidi Lynn Janssen

Occupational Therapy Capstones

Purpose: Interoception refers to one’s ability to sense the internal condition of the body, including sensory messages from body parts and internal organs (Craig, 2002). In the past 30 years, scientists and researchers have discovered a powerful connection between interoceptive appraisal skills and self-regulation, emotional identification, emotional regulation, social skills, and nearly every task in daily life (Mahler, 2017). The purpose of this project is to provide practitioners with an educational platform that describes the sensorimotor skill of interoception applied throughout the occupational therapy process.

Methods: The development of this product was initiated with a thorough review of literature to …

2022-2023 Undergraduate Bulletin, Rochester Institute Of Technology

RIT Digital Archives

No abstract provided.

Metabolic Alterations For Increased Glycogen And Poly(3-Hydroxybutyrate) Production In Cyanobacterium Synechocystis Sp. Pcc 6803, Nannaphat Sukkasam

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cyanobacteria are a potential biofactory for biopolymer production because they can convert greenhouse gas carbon dioxide and light to useful biopolymers. Synechocystis sp. PCC 6803 is a widely used model cyanobacterium due to its simple genetic information and known biochemistry metabolism. This research aims to develop strategies to increase the accumulation and productivity of biopolymers, poly(3-hydroxybutyrate) (PHB) and glycogen, which are required in current and future industries. Three strategies, namely genetic engineering, metabolic inhibition using chemical treatment, and culture media optimization (regarding nitrogen supply), were studied, as well as their combination to increase the PHB and/or glycogen production. Genetic engineering …

Effects Of Articular Knee Injections On Cartilage Of Knee Osteoarthritis Patients And Development Of Rapid Decalcification Method For Articular Cartilage And Subchondral Bone, Pattaranatcha Charnwichai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Osteoarthritis (OA) is the most common degenerative joint disease that affects articular cartilage. Intra-articular injection (IA) is one of the treatments that is used to reduce pain and relieve symptoms. Triamcinolone acetonide (TA) and hyaluronic acid (HA) are frequently used in IA injections for OA treatment. Several publications have reported effects of TA, but some of HA, on articular cartilage. Moreover, for histopathological studies, articular cartilage and subchondral bones are commonly used as samples, but the decalcification process is time consuming. Thus, this study aims to compare effects of drugs used in IA injections on cartilage and chondrocytes of osteoarthritis …