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Articles 49081 - 49110 of 240206
Full-Text Articles in Entire DC Network
Thermal Stability And Decomposition Of Per- And Polyfluoroalkyl Substances (Pfas) Using Granular Activated Carbon And Other Porous Materials, Pavankumar Challa Sasi
Thermal Stability And Decomposition Of Per- And Polyfluoroalkyl Substances (Pfas) Using Granular Activated Carbon And Other Porous Materials, Pavankumar Challa Sasi
Theses and Dissertations
Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals that have been produced for decades as either processing aids or individual ingredients in many industrial and commercial products, including aqueous film-forming foams (AFFFs), non-stick cookware, and fast-food packaging. PFOA and PFOS have been reported in >95% of blood samples collected during multiple U.S. national surveys at concentrations that are a risk to human health. Thermal treatment is routinely used to reactivate the spent granular activated carbon (GAC) from water purification facilities. The aims of this study were: (1) to improve our understanding of the thermal stability of per- and polyfluoroalkyl substances; …
Juvenile Temperature Regulation In Apis Mellifera (Honey Bee) And The Impacts Of Brood Temperature Requirements On The Colony, Scott Debnam
Juvenile Temperature Regulation In Apis Mellifera (Honey Bee) And The Impacts Of Brood Temperature Requirements On The Colony, Scott Debnam
Graduate Student Theses, Dissertations, & Professional Papers
Little is known about the energetic costs to insects of raising young. Honey bees collectively raise young, or brood, through a series of complex behaviors that appear to accelerate and synchronize the timing of brood maturation. These include maintaining the brood nest at warmer and consistent temperatures and the exceptional activity of "heater bees." The temperature at which juvenile insects are raised can profoundly affect their development. Apis mellifera (Honey bees) cope with temperature-dependent development via social behavior that maintains the relatively high and constant temperatures within the nest where the brood are raised. Yet juvenile honey bee development is …
Effectiveness Of General Practitioner-Delivered Nutrition Care Interventions On Dietary And Health Outcomes In Adults With Diet-Related Chronic Conditions: A Systematic Review Protocol, Kathryn E. Asher, Mari Somerville, Shelley Doucet, Alison Luke, Lauren Ball, Stephan U. Dombrowski, Mary Hickson, Richelle Witherspoon
Effectiveness Of General Practitioner-Delivered Nutrition Care Interventions On Dietary And Health Outcomes In Adults With Diet-Related Chronic Conditions: A Systematic Review Protocol, Kathryn E. Asher, Mari Somerville, Shelley Doucet, Alison Luke, Lauren Ball, Stephan U. Dombrowski, Mary Hickson, Richelle Witherspoon
School of Health Professions
Objective: This systematic review will evaluate the effectiveness of nutrition care interventions delivered by general practitioners (GPs) versus usual care or no care on dietary and health outcomes in adults with diet-related chronic conditions or risk states. Introduction: GPs are usually the first contacts for patients with diet-related chronic conditions in the healthcare system. While there is some evidence that GPs can be effective in delivering nutrition care for a number of outcomes, an update to the evidence is required as well as an examination of which components are associated with positive outcomes in order to inform future care. Inclusion …
Contributions Of Agroforestry Systems To Food Provisioning Of Peasant Households: Conflicts And Synergies In Chiapas, Mexico, Lorena Soto-Pinto, Sandra Escobar Colmenares, Marina Benítez Kanter, Angelita López Cruz, Erin Estrada Lugo, Balente Herrera Hernández, Estelí Jiménez-Soto
Contributions Of Agroforestry Systems To Food Provisioning Of Peasant Households: Conflicts And Synergies In Chiapas, Mexico, Lorena Soto-Pinto, Sandra Escobar Colmenares, Marina Benítez Kanter, Angelita López Cruz, Erin Estrada Lugo, Balente Herrera Hernández, Estelí Jiménez-Soto
School of Geosciences Faculty and Staff Publications
Traditional agroforestry systems are widely recognized for their contributions to provisioning, support, regulation, and cultural services. However, because of the advancement of industrial agriculture and a corporative food system, peasants' food systems are rapidly undergoing transformation. We identify the contributions of four types of agroforestry systems (AFS)—shade cocoa agroforest, shade coffee agroforest, milpas and homegardens—to food provisioning in peasant families and discuss conflicts between traditional food systems and the contemporary industrial model of production and consumption confronted by peasants and semi-proletarian migrants. We carried out research in 17 peasant communities in Chiapas, Mexico, and conducted 97 semi-structured interviews and agroecological …
Implementing A Faith-Based Weight Loss Outreach Program For The Westside Community Of Jacksonville, Florida, Jonathan Peinado
Implementing A Faith-Based Weight Loss Outreach Program For The Westside Community Of Jacksonville, Florida, Jonathan Peinado
Doctor of Ministry Projects
Problem
Jacksonville, Florida’s adult population has an obesity rate of 65.4% which is slightly lower than both regional and national averages (66.1%) but higher than the state average (63.2%).
Method
A faith-based weight loss program was developed for the residents of the west side of Jacksonville. The intervention incorporated behavioral, spiritual, and psychological modules. The program lasted a total of 10 weeks from beginning to end, with the main segment taking place over a 40-day (6-week) period. Participants underwent two biometric screenings, one at the beginning of the program and one at the end. They had daily health challenges such …
Inverse Association Between Yogurt Consumption And Metabolic Syndrome Prevalence In United States Adult Males, But Not In Females Or In The Total Population: Nhanes 2017-2018, Diana K. Lee
Master's Theses
Metabolic syndrome (MetS) is prevalent in the United States (US) population andconcerns lie in related chronic diseases and financial burdens. To mitigate MetS, modifying the diet is a possible solution. Yogurt is known for its nutrient density and is a possible health food. The growing interests in yogurt and the growing concerns for MetS are met with the gap of unraveling the yogurt consumption status and MetS prevalence in the US. We evaluated the association between yogurt consumption and MetS using the National Health and Nutrition Examination Survey (NHANES) 2017-2018 and Food and Nutrient Database for Dietary Studies data. The …
No Association Between Macronutrient Intake And Body Composition Indices In Collegiate Athletes, Bryan Singharaj
No Association Between Macronutrient Intake And Body Composition Indices In Collegiate Athletes, Bryan Singharaj
Master's Theses
A scarcity of literature follows the relationship between macronutrient intake and bodycomposition indices within an athletic population. Therefore, the primary aims of the present study were to evaluate the relationship between the percent intake of carbohydrates, dietary fat, and protein with fat-free mass percentage (FFM %), fat mass percentage (FM %), fat mass index (FMI), and lean mass index (LMI). In addition, a secondary objective was to determine if there were any sex differences in the relationship between macronutrient intake and body composition indices. A total of 58 San José State University student-athletes from multiple sports were included in the …
Evaluating Schizochytrium Sp. As An Alternative Ingredient In Fish-Free Feeds For Sablefish (Anoplopoma Fimbria) Aquaculture, Katherine A. Neylan
Evaluating Schizochytrium Sp. As An Alternative Ingredient In Fish-Free Feeds For Sablefish (Anoplopoma Fimbria) Aquaculture, Katherine A. Neylan
Master's Theses
Alternative feeds for marine finfish aquaculture are critical for the sustainable expansionof the aquaculture industry. Fish that are farmed for human consumption are often carnivorous; therefore, the industry uses wild-caught forage fish as a primary ingredient in feeds in the form of fishmeal and fish oil. As the aquaculture industry grows, it is important to identify alternative feed ingredients with high omega-3 polyunsaturated fatty acid (PUFA) concentrations. This study was designed to test a microalga, Schizochytrium sp., as an alternative feed ingredient for sablefish (Anoplopoma fimbria) using six test diets. The first diet (+FM+FO) contained both fishmeal and fish oil. …
Prenatal And Pediatric Oral Health Education Among Dental Hygiene Programs In The United States, Denise M. Claiborne, Shillpa Naavaal
Prenatal And Pediatric Oral Health Education Among Dental Hygiene Programs In The United States, Denise M. Claiborne, Shillpa Naavaal
Dental Hygiene Faculty Publications
Purpose: Health care and dental providers must be prepared to address the oral health needs of mothers and children in order to reduce the burden of dental disease in these populations. The purpose of this study was to describe the curriculum and clinical experiences related to prenatal and pediatric oral health in the university and community college dental hygiene programs in the United States (US).
Methods: Dental hygiene program directors (PDs) from across the US were invited to participate in a cross-sectional electronic survey regarding the prenatal and pediatric oral health curriculum at their institution. In addition to program characteristics, …
Cultivation Of Industrial Hemp On And Near Airports: Implications For Wildlife Use And Risk To Aviation Safety, Bradley F. Blackwell, Page E. Klug, Lee A. Humberg, Zachary T. Brym, Bryan M. Kluever, Jennifer M. Edwards
Cultivation Of Industrial Hemp On And Near Airports: Implications For Wildlife Use And Risk To Aviation Safety, Bradley F. Blackwell, Page E. Klug, Lee A. Humberg, Zachary T. Brym, Bryan M. Kluever, Jennifer M. Edwards
Human–Wildlife Interactions
Land-use planning on and near airports should consider possible revenue from land covers, associated maintenance costs, and potential for land covers to attract vertebrate species recognized as hazardous to aviation safety. The U.S. Federal Aviation Administration has expressed interest in recent attention given to industrial hemp (Cannabis sativa L.; hemp) as a revenue-producing land cover that might be cultivated on or near airports. Our purpose was to better understand the potential production value of hemp as well as its possible role in affecting aviation safety if cultivated on or near airports. Our objectives were to: (1) review the literature …
Industrial Hemp As A Resource For Birds In Agroecosystems: Human–Wildlife Conflict Or Conservation Opportunity?, Emily A. Kotten, Iona Hennessy, Bryan M. Kluever, Zachary T. Brym, Bradley F. Blackwell, Lee A. Humberg, Page E. Klug
Industrial Hemp As A Resource For Birds In Agroecosystems: Human–Wildlife Conflict Or Conservation Opportunity?, Emily A. Kotten, Iona Hennessy, Bryan M. Kluever, Zachary T. Brym, Bradley F. Blackwell, Lee A. Humberg, Page E. Klug
Human–Wildlife Interactions
Industrial hemp (Cannabis sativa L.; hemp) is an emerging crop in the United States with little known about bird use or the potential for birds to become an agricultural pest. We identified birds associated with hemp fields, using repeated visits to oilseed plots in North Dakota, USA (n = 6) and cannabinoid (CBD) plots in Florida, USA (n = 4) from August to November 2020. We did not control for plot area or density; our observations were descriptive only. We observed 10 species in hemp, 12 species flying over hemp, and 11 species both foraging in and …
Appraisal Of Institutional Antimicrobial Stewardship In Selected Public Health Facilities In Nigeria, Joshua Olusegun Obasanya
Appraisal Of Institutional Antimicrobial Stewardship In Selected Public Health Facilities In Nigeria, Joshua Olusegun Obasanya
Walden Dissertations and Doctoral Studies
The misuse of antimicrobials (AM) constitutes a huge problem in developing countries, including Nigeria, posing severe public health threats to the populace’s health. Misuse contributes to the high consumption of AM, driving the emergence and spread of antimicrobial resistance (AMR). Establishing functional antimicrobial stewardship (AMS) programs at the health facility levels is recognized as an effective and efficient strategies to tackle AMR. Literature is replete with evidence of poor prescription practices, but few studies assessing the factors contributing to inappropriate use of AM in Nigeria exist. The purpose of this study was to improve the understanding of AMS practice at …
Exploring Parent Support For School-Based Health Programs To Reduce Childhood, Alaphiah Delaney Campbell Byfield
Exploring Parent Support For School-Based Health Programs To Reduce Childhood, Alaphiah Delaney Campbell Byfield
Walden Dissertations and Doctoral Studies
The rise in childhood obesity rates continues globally despite the design and implementation of social programs aimed at curtailing that phenomenon. The government of Jamaica has indicated that a whole-of-government, whole-of-society approach is needed to control obesity. The literature has shown that in Jamaica, support for being fluffy impedes progress toward addressing the problem of childhood obesity; being fluffy is considered attractive and a sign that one has a good life. Studies have shown that obese or overweight children are at risk for developing psychosocial (e.g., having low self-esteem, and underperforming academically) and medical problems (e.g., noncommunicable diseases such as …
Health Educators’ Perspectives On Black And Latin@ College Students’ Health Literacy, Desiree Williams Brown
Health Educators’ Perspectives On Black And Latin@ College Students’ Health Literacy, Desiree Williams Brown
Walden Dissertations and Doctoral Studies
AbstractEmerging adulthood is a critical life stage when participation in higher education can facilitate the transition of young individuals into adulthood and independence. The barriers associated with low health literacy levels are higher among racial or ethnic groups facing health inequalities, including those enrolled in higher education institutions. The purpose of this basic qualitative study was to explore how health educators promoted the health literacy of Black and Latino emerging adult college students. The theoretical framework was based on Bandura’s social cognitive theory. Eight health professionals who served to promote health literacy across diverse college campuses and different states in …
Chronic Kidney Disease And Depressive Disorders Among Adult Non-Hispanic African Americans And Whites In Georgia, Omatola Gordon-Rose
Chronic Kidney Disease And Depressive Disorders Among Adult Non-Hispanic African Americans And Whites In Georgia, Omatola Gordon-Rose
Walden Dissertations and Doctoral Studies
Chronic kidney disease (CKD), depressive disorders, and mental health are significant health issues in the United States. The purpose of this study was to examine the association of CKD and depressive disorders and days of poor mental health in adults living in Georgia, controlling for race/ethnicity, socioeconomic status, gender, age, diabetes mellitus status, high blood pressure status, marital status, and number of adults in the household. The study was a descriptive, quantitative, cross-sectional design with secondary data analysis, and the framework used was Wilson and Cleary health-related quality of life measures. The 2019 Behavioral Risk Factor Surveillance System Survey weighted …
Fat Rights, Public Health Oppression And Prejudice, And The “Obesity Epidemic”, Nicholas D. Lawson
Fat Rights, Public Health Oppression And Prejudice, And The “Obesity Epidemic”, Nicholas D. Lawson
Touro Law Review
The pervasiveness, frequency, and intensity of fat shaming, bullying, and harassment experienced by fat people is well-documented, and three quarters of the American public support antidiscrimination protections for fat people. Yet fat people generally remain unprotected from discrimination under federal and state law in all but two jurisdictions. This Article traces these problems to the agendas of public health leaders, organizations (the Centers for Disease Control and Prevention and the World Health Organization), and associated industries, which are fighting an “obesity epidemic.” It describes some of their fat-shaming strategies and persistent public-health-crisis framings, as well as sensationalized presentations of research …
The Effect Of Parental Socialization On The Postsecondary Plans Of Latino/Hispanic Students, Nilda Ivette Rosario
The Effect Of Parental Socialization On The Postsecondary Plans Of Latino/Hispanic Students, Nilda Ivette Rosario
Walden Dissertations and Doctoral Studies
Latino/Hispanics are one of the largest ethnic minority groups in the United States, yet they are underrepresented in higher education. Grounded on the social cognitive theory and the Hoover-Dempsey and Sandler model, the purpose of this study was to examine the relationship between parental expectations, parental involvement, parental self-efficacy, and postsecondary planning of Latino/Hispanic students. The research questions were formulated to determine whether parental factors among Latino/Hispanic parents can predict postsecondary educational outcomes among Latino/Hispanic students. A quantitative correlational research study design was used. The target population was Latino/Hispanic parents residing in the United States with at least one child …
Disparities In Caregiver-Reported Dental Cavities And Toothaches Among Children In The Special Supplemental Nutrition For Women, Infants, And Children (Wic) Program, Denise M. Claiborne, Chun Chen, Qi Zhang
Disparities In Caregiver-Reported Dental Cavities And Toothaches Among Children In The Special Supplemental Nutrition For Women, Infants, And Children (Wic) Program, Denise M. Claiborne, Chun Chen, Qi Zhang
Dental Hygiene Faculty Publications
Purpose: Dental caries is prevalent among low-income and minority children despite oral health promotion programs. The purpose of this study was to examine disparities associated with caregiver-reported cavities and toothaches among children in the United States aged 2-4 years by their eligibility for and participation in the Special Supplemental Nutrition for Women, Infants, and Children (WIC) program.
Methods: A secondary data analysis was performed using the 2016 National Survey of Children's Health (NSCH) data on children aged 2-4 years (n=7,719) with complete WIC participation information. Three groups were formed based on WIC eligibility and participation status: WIC participants, income-eligible non-participants, …
Oral Health Literacy Inventories For Caregivers Of Preschool-Aged Children: A Systematic Review, Melissa L. Sullivan, Denise M. Claiborne, Deanne Shuman
Oral Health Literacy Inventories For Caregivers Of Preschool-Aged Children: A Systematic Review, Melissa L. Sullivan, Denise M. Claiborne, Deanne Shuman
Dental Hygiene Faculty Publications
Purpose: The purpose of this systematic review was to describe the oral health literacy (OHL) inventories that have been used among caregivers of preschool-aged children.
Methods: Four databases were searched (CINAHL, Cochrane Database of Systematic Reviews, Dentistry & Oral Sciences Source, PubMed), to identify peer-reviewed, full-text studies published in English on the oral health literacy among caregivers of preschool-aged children from 2010-2021. All studies were assessed for eligibility using PRISMA guidelines. Inclusion criteria were experimental, non-experimental, or mixed methods peer-reviewed studies, conducted in the United States. Eligible studies were independently evaluated using the Effective Public Health Practice Project's Quality Assessment …
The Association Between Early Enteral Nutrition And Various Outcomes In Patients Undergoing Ecmo Therapy At Loma Linda University Medical Center, Torrey Mitsunga, Lauren Wheeler
The Association Between Early Enteral Nutrition And Various Outcomes In Patients Undergoing Ecmo Therapy At Loma Linda University Medical Center, Torrey Mitsunga, Lauren Wheeler
Loma Linda University Research Reports
Introduction:
Extracorporeal membrane oxygenation (ECMO) therapy is a life-saving option for critically ill patients who require either pulmonary and hemodynamic support. ECMO has only been widely adapted for usage in adults over the last few years, and recently at higher rates due to Covid-19. Though ECMO has the potential to save lives, it presents many challenges related to feeding and nourishment of the patients. Currently, data is lacking on how enteral nutrition during ECMO affects outcomes such as the duration of hospitalization, ability to meet calorie and protein goals, and patient survival.
Consistency Of Noncommercial Based Thickening Agents On Llumc Dysphagia Menu Items, Andreena Lopez, Briana Tran, Janelle Tse
Consistency Of Noncommercial Based Thickening Agents On Llumc Dysphagia Menu Items, Andreena Lopez, Briana Tran, Janelle Tse
Loma Linda University Research Reports
Introduction:
More than 60% of the population 60 years and above experience some level of dysphagia. Patients with a medical history such as stroke, Alzheimer’s disease, autoimmune diseases, and gastroesophageal reflux may also have an increased risk for dysphagia. The International Dysphagia Diet Standardization Initiative (IDDSI) is a framework covering the global standards for dysphagia modified food texture descriptions. Current literature related to food thickeners in dysphagia management observe the suitability of various thickeners on all levels of dysphagia. However, many of these studies may or may not compare their findings with the current IDDSI guidelines.
The Effect Of A Four Week Nutrition Education Program On Knowledge & Behavioral Changes In The East La/Boyle Heights Community, Manuel Rodriquez, Santiago Melendez
The Effect Of A Four Week Nutrition Education Program On Knowledge & Behavioral Changes In The East La/Boyle Heights Community, Manuel Rodriquez, Santiago Melendez
Loma Linda University Research Reports
Introduction:
Over the past three decades, obesity rates in the United States have doubled among adults and tripled amongst children. According to a Los Angeles County Public Health report, overweight and obesity cases account for 3.43 billion dollars annually of county expenses. Despite all this capital being spent on obesity, preventative plans, obesity rates continue to rise. The most affected areas in Los Angeles County are Compton, La Puente, and East Los Angeles. This is where most African American and Latino communities reside. Of the obese population in LA County, Latinos make up the largest percentage with 29.4% .
The Efficacy Of Probiotics On Overall Quality Of Life By Gender, Melissa Kalman, Kirsten Soderblom
The Efficacy Of Probiotics On Overall Quality Of Life By Gender, Melissa Kalman, Kirsten Soderblom
Loma Linda University Research Reports
Introduction:
In the 1950s, German scientist Werner Kollath coined the term probiotic, which is Latin for, “for life”. To be considered a probiotic, a product must consist of live microorganisms and provide health benefits to the host when ingested in sufficient amounts. The microorganisms in probiotics provide numerous health benefits through immunologic mechanisms. Recent research shows probiotics may provide benefits to those experiencing stress, including general anxiety and stressors, as well as improve human immunity and overall quality of life. There is a lack of research concerning probiotics and the differences in physiological responses comparing males and females.
Comparison Of Student Dietary Patterns In The School Of Allied Health Professions' Departments, Randy Song, Sonya Fargo, Jaime Scolastico
Comparison Of Student Dietary Patterns In The School Of Allied Health Professions' Departments, Randy Song, Sonya Fargo, Jaime Scolastico
Loma Linda University Research Reports
Introduction:
Dietary habits influence many risk factors for cardiometabolic health, including heart disease, stroke, and type 2 diabetes, which collectively pose substantial health and economic burdens. College students may struggle to get access to or understand how to prepare healthy foods. Students with more nutritional knowledge consume less unhealthful fats and cholesterol, but as independence increases, students are continuously challenged to make healthful food choices. Assessing dietary patterns can be complex and time consuming, though it is a worthwhile endeavor as it sheds light on diet quality and areas of excess and deficiency.
Thinking, Faster And Slower: Toward A Dynamic View Of Organizational Cognition, Joseph Vukov, Charles Lassiter
Thinking, Faster And Slower: Toward A Dynamic View Of Organizational Cognition, Joseph Vukov, Charles Lassiter
Philosophy Faculty Scholarship
Our abilities as humans—i.e. our powers—aren’t always stable across contexts. In particular, sociocultural contexts can amplify or dampen manifestations of our powers. In particular, the same sociocultural intervention can catalyze a manifestation for one sort of individual and inhibit it for another. We develop these insights within the conceptual framework of causal powers realism: An ontological theory built on the idea that causal influences and processes should ultimately be understood as the manifestation of powers. Developing capacities’ dynamism in this framework enables articulation of novel insights. First, that our psychological capacities are context-sensitive and dynamic all the way down. Second, …
Conservation Value Of Working Landscapes In Mesoamerica For Nearctic-Neotropical Migratory Birds, Samuel L. Oliveira
Conservation Value Of Working Landscapes In Mesoamerica For Nearctic-Neotropical Migratory Birds, Samuel L. Oliveira
Dissertations, Master's Theses and Master's Reports
Populations of many of Nearctic-neotropical migratory birds have declined in the past several decades, recent estimates suggested a dramatic loss of 2.5 billion birds over the past 50 years in North America. Habitat loss and degradation represent a major threat in the tropics. Managed agroecosystems have the potential to mitigate some impacts of land conversion, however, little is known regarding the habitat quality provided by working landscapes in the overwintering range. In this research, we surveyed the migratory bird community in the rapidly expanding oil palm plantations in southern Mexico; and also the declining population of the Wood Thrush ( …
การศึกษาแบบสุ่มของการให้วิตามินดีขนาดคงที่เปรียบเทียบกับการปรับขนาดตามระดับวิตามินดีในเลือดในผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไต, สรัลชนา เจียมพจมาน
การศึกษาแบบสุ่มของการให้วิตามินดีขนาดคงที่เปรียบเทียบกับการปรับขนาดตามระดับวิตามินดีในเลือดในผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไต, สรัลชนา เจียมพจมาน
Chulalongkorn University Theses and Dissertations (Chula ETD)
ที่มาของงานวิจัย: ภาวะพร่องวิตามินดีสัมพันธ์กับมวลกล้ามเนื้อที่น้อย เสียการทำงานของกล้ามเนื้อ ระบบหัวใจและหลอดเลือด ระบบภูมิคุ้มกันและอัตราการเสียชีวิตในผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไต แต่อย่างไรก็ตามยังไม่มีข้อสรุปว่าควรแก้ไขภาวะพร่องวิตามินดีในผู้ป่วยกลุ่มนี้อย่างไรจึงจะดีที่สุด วัตถุประสงค์งานวิจัย: งานวิจัยนี้จัดทำขึ้นเพื่อประเมินผลของการให้วิตามินดีสูตรที่แตกต่างกันต่อร้อยละของผู้ป่วยที่มีภาวะวิตามินดีเพียงพอ (ระดับวิตามินดีในเลือดมากกว่าหรือเท่ากับ 30 นาโนกรัมต่อมิลลิลิตร) ในผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไต ระเบียบวิธีวิจัย: การศึกษานี้เป็น randomized, controlled trial (ClinicalTrial.gov NCT05434377) โดยผู้วิจัยได้สุ่มผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไตโดยการฟอกเลือดหรือล้างไตทางช่องท้องร่วมกับมีภาวะพร่องวิตามีนดีซึ่งหมายถึงระดับวิตามินดีในเลือดน้อยกว่า 30 นาโนกรัมต่อมิลลิลิตร เป็นสองกลุ่มด้วยอัตราส่วน 1:1 คือกลุ่มแรกให้ ergocalciferol รับประทานขนาดคงที่ 20,000 ยูนิตต่อสัปดาห์ และกลุ่มที่สองให้แบบปรับขนาดตามระดับวิตามินดีในเลือดเป็นกลุ่มควบคุม การวิจัยนี้ได้ศึกษา primary outcome เป็นการเปรียบเทียบร้อยละของผู้ป่วยที่มีภาวะวิตามินดีเพียงพอในแต่ละกลุ่มภายหลังได้รับ ergocalciferol เป็นระยะเวลา 24 สัปดาห์ ผลการศึกษา: ผู้เข้าร่วมวิจัยทั้งหมด 71 คนที่ติดตามจนครบ 24 สัปดาห์โดยมีสัดส่วนของผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไตด้วยการฟอกเลือดร้อยละ 45 โดยไม่มีความแตกต่างกันของอายุ โรคประจำตัว ระดับวิตามินดีในเลือด มวลกล้ามเนื้อ ความแข็งแรงของกล้ามเนื้อ ระดับแคลเซียมและฟอสฟอรัสในเลือด และระยะเวลาการบำบัดทดแทนไตไม่มีความแตกต่างกันในทั้งสองกลุ่ม หลังจากได้รับวิตามินดีพบว่าไม่มีความแตกต่างของร้อยละของผู้ป่วยที่มีภาวะวิตามินดีเพียงพอระหว่างกลุ่มที่ได้รับวิตามินดีขนาดคงที่ (49%) และแบบปรับขนาดตามระดับวิตามินดีในเลือด (39%) (p=0.41) แต่พบว่าค่าเฉลี่ยของระดับวิตามินดีในเลือดเพิ่มขึ้นอย่างมีนัยยะสำคัญทางสถิติในทั้งสองกลุ่ม ค่าเฉลี่ยของมวลกล้ามเนื้อ (BIS-derived total-body muscle mass normalized to height squared) เพิ่มขึ้นอย่างมีนัยยะสำคัญที่ 24 สัปดาห์ ในกลุ่มได้รับวิตามินดีขนาดคงที่ (14.4±3.4 เป็น 15.3±3.0 kg/m2, p=0.03) เปรียบเทียบกับกลุ่มปรับขนาดตามระดับวิตามินดีในเลือด (13.6±2.7 เป็น 13.7±3.0 kg/m2, p=0.58) โดยได้รับพลังงานและโปรตีนใกล้เคียงกัน แต่อย่างไรก็ตามความแข็งแรงของกล้ามเนื้อและความเร็วในการเดิน (gait speed) ไม่มีความแตกต่างกันระหว่างสองกลุ่ม (p>0.05) สรุปผลการศึกษา: การให้วิตามินดีในผู้ป่วยโรคไตระยะสุดท้ายที่ได้รับการบำบัดทดแทนไตสามารถเพิ่มระดับวิตามินดีในเลือดได้อย่างมีนัยยะสำคัญ ผลของการให้วิตามินดีระหว่างการให้ขนาดคงที่และการปรับขนาดตามระดับวิตามินดีในเลือดไม่พบความแตกต่างในร้อยละของผู้ป่วยที่มีระดับวิตามินดีเพียงพอที่ 24 สัปดาห์ แต่การให้วิตามินดีขนาดคงที่พบว่ามีมวลกล้ามเนื้อเพิ่มขึ้นกว่าการให้แบบปรับขนาดตามระดับวิตามินดีในเลือด
Effects Of Azadirachta Indica Extract On Inhibition Of Glutamate-Induced Neuronal Cell Apoptosis Via Preventing Excessive Mitophagy Activation And Inhibiting Endoplasmic Reticulum Stress In Ht-22 Cells, Kuljira Mongkolpobsin
Effects Of Azadirachta Indica Extract On Inhibition Of Glutamate-Induced Neuronal Cell Apoptosis Via Preventing Excessive Mitophagy Activation And Inhibiting Endoplasmic Reticulum Stress In Ht-22 Cells, Kuljira Mongkolpobsin
Chulalongkorn University Theses and Dissertations (Chula ETD)
Neurodegenerative diseases (NDs) are the age-related diseases which represent a major cause of mortality in aging population nowadays. Previous studies have shown that glutamate, the most abundant excitatory neurotransmitter, significantly increases in extracellular fluid of the patient’s brain and is the cause of neurodegeneration in NDs. The increase of extracellular glutamate elevates reactive oxygen species (ROS) accumulation and calcium (Ca2+) which exacerbate mitochondrial function, followed by inducing MAPK pathway and endoplasmic reticulum (ER) stress, respectively. In addition, Ca2+ overload also triggers calpain, a Ca2+ dependent protease, activity which further stimulates Cdk5/p35/p25 signaling leading to neuronal apoptosis. Azadirachta indica A. Juss. …
Arlington: An Age And Dementia Friendly Action Plan, Caitlin Coyle, Beth Rouleau, Nidya Velasco-Roldán, Rebecca Mailman
Arlington: An Age And Dementia Friendly Action Plan, Caitlin Coyle, Beth Rouleau, Nidya Velasco-Roldán, Rebecca Mailman
Center for Social and Demographic Research on Aging Publications
This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA) within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Town of Arlington and the Arlington Council on Aging. This plan was created uniquely for Arlington, with input from residents, community partners, local businesses, government leaders and aging experts. Surveys were conducted, focus groups were held and feedback was collected both pre and post-pandemic to create a plan that reflects the dynamic environment that we are all living in. Using collected data, survey results, feedback and input, this plan was …
Immersive Expereince For Wellness Tourism Within Thailand Context, Natnisha Kongtaveesawas
Immersive Expereince For Wellness Tourism Within Thailand Context, Natnisha Kongtaveesawas
Chulalongkorn University Theses and Dissertations (Chula ETD)
The emerging immersive tourism technology has contributed to development of the tourism field since it provides an interactive computer-generated medium that allows participants to create simulated experiences of both real and unreal situations. Immersive tourism technology provides travelers with the unique experience of the destination and can play a significant role in encouraging actual visitation and engaging both travelers and destinations in particular travel activities. The previous research on a theoretically integrated PMSE experience framework and immersive tourism technology within Thailand context has not previously been conducted with respect to wellness tourism. To address this gap, this study develops and …