Digital Commons Network^™

Creation Care, Human Wellness, And Sustainability, Omoike Eric Aizenofe

Electronic Theses and Dissertations

In this thesis, I argue that creation care contributes to human wellness and to sustainable living on earth. Within contemporary contexts, humans are suffering spiritually, mentally, and emotionally. This distress impairs wellness and reduces peoples’ capacity to contribute to sustainable solutions and earth-positive impacts. Creation care entails conscious and intentional activities that are carried out for the health of the created world. Creation care contributes to human wellness, spiritually, mentally, and emotionally by offering spaces, environments, co-habitations, and interdependency among its components that support human wellness and sustainable living. Creation care helps fight spiritual, mental, and emotional distress so that …

The Experience Of Music Therapists Working With The Parents Of Premature Infants In The Neonatal Intensive Care Unit (Nicu), Harria Kim

Theses & Dissertations

This study explored the lived experience of music therapists working with parents of premature infants in the neonatal intensive care unit (NICU). While there are many studies regarding the effects of music therapy on parents and premature infants in the NICU, few in-depth qualitative studies focus on the experiences and perspectives of music therapists working in the NICU. The present study aims to explore music therapists’ experiences of working with the parents of premature infants in the NICU and their perspectives on how music therapy can meet the needs of these parents. Data were collected through audio-video recording and transcription …

Subjective Well-Being And Bilateral Anterior Insula Functional Connectivity After Exercise Intervention In Older Adults With Mild Cognitive Impairment, Junyeon Won, Kristy A. Nielson, J. Smith Carson

Psychology Faculty Research and Publications

While it is well known that exercise training is associated with improvement in subjective well-being among older adults, it is unclear if individuals with cognitive impairment experience the same effects elicited by exercise on subjective well-being. We further explored whether the bilateral anterior insula network may be an underlying neural mechanism for the exercise training-related improvements in subjective well-being. We investigated the effects of exercise training on subjective well-being in older adults (78.4 ± 7.1 years) with mild cognitive impairment (MCI; n = 14) and a cognitively normal (CN; n = 14) control group. We specifically assessed the relationship between …

Sustainable Applications Of Biochar Derived From Food Waste And Paper Feedstocks, Steven T. Barber

Theses

There is general agreement in the scientific literature that carbon sequestration is an important tool to mitigate human-induced climate change, but current methods are lacking scalability and economic viability. Though charcoal has been a common fuel for millennia, it has only very recently been purposefully created to sequester carbon. This carbon dense material, called biochar, has been extensively studied as a soil amendment though less studied for industrial applications. Chapter 1 provides an in-depth overview and background discussion of the history and definitions of biochar, distinguishing it from closely related though often misconstrued terms like charcoal, activated carbon, and carbon …

The Restaurant Meals Program: A Guide For New York State’S Successful Implementation, Evan Cohen

Theses

In October 2021, New York State (NYS) Governor Kathy Hochul signed into law legislation enacting the Restaurant Meals Program (RMP) to the Supplemental Nutrition Assistance Program (SNAP). The RMP is an extension of SNAP, allowing eligible SNAP recipients to spend their benefits at restaurants. The goal of the RMP is to allow a targeted SNAP population—the elderly, disabled, and homeless—to have greater accessibility to purchase prepared, low-cost, hot meals that would otherwise be out of reach. Restaurant Meals Programs are currently enacted in just six states. Few analyses have evaluated its strengths and weaknesses. By identifying the RMP-eligible population’s food-related …

Watch Your Flavors: Augmenting People's Flavor Perceptions And Associated Emotions Based On Videos Watched While Eating, Meetha Nesam James, Nimesha Ranasinghe, Anthony Tang, Lora Oehlberg

Research Collection School Of Computing and Information Systems

People engage in different activities while eating alone, such as watching television or scrolling through social media on their phones. However, the impacts of these visual contents on human cognitive processes, particularly related to flavor perception and its attributes, are still not thoroughly explored. This paper presents a user study to evaluate the influence of six different types of video content (including nature, cooking, and a new food video genre known as mukbang) on people’s flavor perceptions in terms of taste sensations, liking, and emotions while eating plain white rice. Our findings revealed that the participants’ flavor perceptions are augmented …

Childhood Mortality During And After Acute Illness In Africa And South Asia: A Prospective Cohort Study, Childhood Acute Illness And Nutrition (Chain) Network, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Ali Fazal Khan, Ali Faisal Saleem, Benson O. Singa, Blaise Siezanga Gnoumou, Caroline Tigoi, Syed Asad Ali, Zaubina Kazi

Department of Paediatrics and Child Health

Background: Mortality among children with acute illness in low-income and middle-income settings remains unacceptably high and the importance of post-discharge mortality is increasingly recognised. We aimed to explore the epidemiology of deaths among young children with acute illness across sub-Saharan Africa and south Asia to inform the development of interventions and improved guidelines.
Methods: In this prospective cohort study, we enrolled children aged 2-23 months with acute illness, stratified by nutritional status defined by anthropometry (ie, no wasting, moderate wasting, or severe wasting or kwashiorkor), who were admitted to one of nine hospitals in six countries across sub-Saharan Africa and …

Characterization Of Folic Acid, 5-Methyltetrahydrofolate And Synthetic Folinic Acid In The High-Affinity Folate Transporters: Impact On Pregnancy And Development, Ana M. Palacios, Rachel A. Feiner, Robert M. Cabrera

Health Policy & Community Health: Faculty Publications

Objectives:

Folates are B vitamins that are essential for several molecular, cellular, and biological processes, including nucleotide synthesis, methylation, and methionine cycling. The physiological impacts of these processes on health also extend to cell proliferation, folate deficiency anemia, and reduction of the risk of birth defects during pregnancy. The primary objective of this study was to characterize the binding affinities of different folate forms, folic acid (FA), 5-methyltetrahydrofolate (5MTHF), and folinic acid, to the folate receptors α and β, and to the bovine milk folate binding protein. These three dietary forms of folate are found in enriched grains (FA), various …

Sarcoid Myelitis Masking As Multiple Sclerosis In An Otherwise Healthy 45-Year-Old: A Case Report, Jesse Lou, Brandon Trivax

Posters

No abstract provided.

The Impact Of Professional Development On Trauma-Informed Practices (Tips) In A Teacher's Feeling Of Self-Efficacy, Christina Kay Cumbest

Doctoral Dissertations and Projects

The purpose of this quantitative, quasi-experimental, static-group comparison design study was to determine the increase or decrease of self-efficacy for elementary and secondary teachers regarding instructional strategies, student engagement, and classroom management after professional development in TIPs. TIPs in the school setting provide comprehensive interventions to address childhood trauma that could promote positive academic progress. There has been little research provided on the impact of TIPs regarding instructional strategies, student engagement, and classroom management as it relates to teacher-efficacy. The results of this study found significant differences in survey responses from teachers in two school districts. The Teachers’ Sense of …

The Effects Of Remote Learning On Slife Students From Central America During The Covid-19 Pandemic, Sarah Katherine Richter

Doctoral Dissertations and Projects

The Covid pandemic caused changes in education of which we may never know or understand all its repercussions to the public education system. One group of vulnerable students, newcomers from Guatemala and Honduras with limited or interrupted formal education (SLIFE), were negatively affected. Due to the COVID-19 pandemic, one SLIFE program sent its students home in the spring of 2020 to quarantine and did not return to in-person learning again until a year later. The purpose of this quantitative, causal comparative study is to investigate the effects of remote learning during the Covid-19 pandemic on SLIFE students’ education while attending …

Fatigue, Schedules, Sleep, And Sleepiness In U.S. Commercial Pilots During Covid-19, Cassie J. Hilditch, Erin E. Flynn-Evans

Faculty Research, Scholarly, and Creative Activity

cOViD-19 has had a significant impact on the aviation industry. While reduced flying capacity may intuitively translate to reduced fatigue risk by way of fewer flights and duty hours, the actual impact of the pandemic on pilot fatigue is unknown. methods: We surveyed U.S. commercial airline pilots in late 2020 (N = 669) and early 2021 (N = 156) to assess the impact of COViD-19 on schedules and fatigue during the pandemic. results: Overall, pilots reported reduced flight and duty hours compared to prepandemic. Average sleep on workdays was slightly shorter in late 2020 (6.87 ± 1.14 h) and recovered …

Mitochondrial Sirtuin-3 (Sirt3) Prevents Doxorubicin-Induced Dilated Cardiomyopathy By Modulating Protein Acetylation And Oxidative Stress, Mateusz M Tomczyk, Kyle G Cheung, Bo Xiang, Nahid Tamanna, Ana L Fonseca Teixeira, Prasoon Agarwal, Stephanie M Kereliuk, Victor Spicer, Ligen Lin, Jason Treberg, Qiang Tong, Vernon W Dolinsky

Faculty, Staff and Students Publications

BACKGROUND: High doses of doxorubicin put cancer patients at risk for developing dilated cardiomyopathy. Previously, we showed that doxorubicin treatment decreases SIRT3 (sirtuin 3), the main mitochondrial deacetylase and increases protein acetylation in rat cardiomyocytes. Here, we hypothesize that SIRT3 expression can attenuate doxorubicin induced dilated cardiomyopathy in vivo by preventing the acetylation of mitochondrial proteins.

METHODS: Nontransgenic, M3-SIRT3 (truncated SIRT3; short isoform), and M1-SIRT3 (full-length SIRT3; mitochondrial localized) transgenic mice were treated with doxorubicin for 4 weeks (8 mg/kg body weight per week). Echocardiography was performed to assess cardiac structure and function and validated by immunohistochemistry and immunofluorescence (n=4-10). …

A Study On The Impact Of Diet On Unified Fire Authority Firefighter Performance, Marin Easton

Undergraduate Honors Capstone Projects

Objective: This project aimed to examine the impact of nutrition knowledge, dietary intake, and physical activity on firefighters’ performance on their routine physical assessment (RPA).

Methodology: Members of the Unified Fire Authority, the largest fire agency in Utah with more than 400 sworn firefighters serving 15 communities representing 440,000 residents, were invited via email to participate in this cross-sectional study. Participants (N=92) completed a 40- question survey that assessed specialized diet adherence, dietary intake, nutrition knowledge (using questions from the General Nutrition Knowledge Questionnaire;1 point for each correct answer [26 points possible]), regular physical activity (International Physical Activity Questionnaire), and …

A Sentiment And Content Analysis Of Facebook Posts Regarding Wild Horse Management, Libbie G. Anderson

Undergraduate Honors Capstone Projects

The purpose of this study was to better understand public sentiment and current conversations on Facebook regarding wild horse management practices, including adoption, roundups, and contraception, in the timeframe between the June 2021 BLM Wild Horse Advisory Board meeting and January 31, 2022. Social media monitoring and quantitative content analysis were used to examine the Facebook posts of four organizations communicating about the wild horse controversy. The research questions guiding this study included: (1) How many total mentions of “fertility control,” “contraception,” “roundup,” “gather,” “adoption,” and “management” as they pertained to wild horses occurred across Facebook from June 1, 2021 …

The Effects Of Strength And Conditioning Training On The Health Of College Students, Brynli Bleak

Undergraduate Honors Capstone Projects

Does participation in Strength and Conditioning (S&C) classes have a positive effect on the physical, emotional, mental, and social health of college students? This study was designed to measure and explore different markers of physical, mental, emotional, and social health from participants in Strength and Conditioning classes. Class participants were asked to complete a survey to self report the effects of the training on various aspects of their life. Data were analyzed and compared to national averages for college students, and correlation tests were conducted to identify relationships in the reported effects. The study found that no significant correlations existed …

Effect Of Basal Diet And Black Raspberry Supplementation On Gene Biomarkers Of "Leaky Gut" In A Mouse Model Of Colitis-Associated Colorectal Cancer, Eliza Catherine Stewart

Undergraduate Honors Capstone Projects

Colorectal cancer is currently the second leading cause of cancer death in the world. The risk of developing colorectal cancer increases significantly in individuals who suffer from colitis, which is inflammation of the colon lining, seen in Irritable Bowel Disease. The term “leaky gut” is often used to describe increased intestinal permeability and is closely related to colitis. Leaky gut is associated with dysbiosis of the gut microbiota, which can occur through diet. This dysbiosis leads to prolonged inflammation and affects genes that encode for proteins involved in the tight junctions between cells. Compromised intestinal integrity allows for translocation of …

The Evolution And Unraveling Of The American Eugenics Movement, Anneka Walton

Undergraduate Honors Capstone Projects

While the evolution of American eugenics surrounding the time of Nazi Germany has been well-documented, the periods before the explosion of American eugenics and the result of the movement in the wake of the Holocaust are not so well known. Many historically-based works have described the path and growth of eugenics from the time the term was coined to the public acknowledgement of World War II and the point where Americans ended eugenic euthanasia and slowed eugenic sterilizations. There are also many works within the realm of disability history that document these events from the more common social viewpoint. This …

Sirolimus (Rapamycin) Induced Mucosal Healing In Anti-Tumor Necrosis Factor Refractory Pediatric Ulcerative Colitis, Richard Kellermayer, Andrew Chang, Kalyani Patel

Faculty, Staff and Students Publications

Sirolimus (rapamycin) has been sparsely reported in the treatment of pediatric ulcerative colitis (PUC). Mucosal healing has not been examined in responders to the drug. We describe a case of infliximab refractory PUC where rapamycin induced sustained clinical remission along with mucosal healing. We conclude that rapamycin should be positioned into the expanding treatment repertoire of PUC.

Prevalence And Clinical Correlates Of Antinuclear Antibody In Patients With Gastroparesis, Henry P Parkman, Mark L Van Natta, Ashima Makol, Madhusudan Grover, Richard W Mccallum, Zubair Malik, Kenneth L Koch, Irene Sarosiek, Braden Kuo, Robert J Shulman, Gianrico Farrugia, Laura Miriel, James Tonascia, Frank Hamilton, Pankaj J Pasricha, Thomas L Abell, Niddk Gastroparesis Clinical Research Consortium

Faculty, Staff and Students Publications

BACKGROUND: Autoimmunity may play a role in the pathogenesis of gastroparesis in a subset of patients. Antinuclear antibody (ANA) testing is often used to screen for autoimmune disorders.

AIMS: 1) Determine prevalence of a positive ANA in patients with gastroparesis; 2) Describe characteristics of idiopathic gastroparesis patients with positive ANA.

METHODS: Patients were assessed with gastric emptying scintigraphy (GES), symptom assessment via Patient Assessment of Upper GI Symptoms [PAGI-SYM], and blood tests-ANA, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP).

RESULTS: Positive ANA was seen in 148 of 893 (17%) patients with gastroparesis, being similar in idiopathic (16% of 536 patients), …

Evaluating Eosinophilic Colitis As A Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study, Tetsuo Shoda, Margaret H Collins, Mark Rochman, Ting Wen, Julie M Caldwell, Lydia E Mack, Garrett A Osswald, John A Besse, Yael Haberman, Seema S Aceves, Nicoleta C Arva, Kelley E Capocelli, Mirna Chehade, Carla M Davis, Evan S Dellon, Gary W Falk, Nirmala Gonsalves, Sandeep K Gupta, Ikuo Hirano, Paneez Khoury, Amy Klion, Calies Menard-Katcher, John Leung, Vincent A Mukkada, Philip E Putnam, Jonathan M Spergel, Joshua B Wechsler, Guang-Yu Yang, Glenn T Furuta, Lee A Denson, Marc E Rothenberg, Consortium Of Eosinophilic Gastrointestinal Diseases Researchers (Cegir)

Faculty, Staff and Students Publications

BACKGROUND & AIMS: Colonic eosinophilia, an enigmatic finding often referred to as eosinophilic colitis (EoC), is a poorly understood condition. Whether EoC is a distinct disease or a colonic manifestation of eosinophilic gastrointestinal diseases (EGIDs) or inflammatory bowel disease (IBD) is undetermined.

METHODS: Subjects with EoC (n = 27) and controls (normal [NL, n = 20], Crohn's disease [CD, n = 14]) were enrolled across sites associated with the Consortium of Eosinophilic Gastrointestinal Disease Researchers. EoC was diagnosed as colonic eosinophilia (ascending ≥100, descending ≥85, sigmoid ≥65 eosinophils/high-power field) with related symptoms. Colon biopsies were subjected to RNA sequencing. Associations …

Regulation Of C-C Chemokine Receptor 7 (Ccr7) Ligand-Mediated Internalization And Chemotaxis By G Protein-Coupled Receptor Kinase Family 4 (Grk-4, 5, 6) In Human Pediatric T-Cell Acute Lymphoblastic Leukemia (T-All), Eduardo Elias Chaib

Open Access Theses & Dissertations

Background and Significance: The Hispanic population is disproportionally affected by T-ALL (T-cell acute lymphoblastic leukemia) when compared to other races in the US. C-C Chemokine Receptor 7 (CCR7) in T-ALL is used during disease progression, and may lead to migration of cancerous cells into the Central Nervous System (CNS) of patients. Goals and Objectives: This project aims to find relevant rates and risk factors for T-ALL for the Hispanic population in the US/Mexico border region. The other aim is to assess the effect of the G protein-coupled Receptor Kinase 4 (GRK-4) family proteins on migration and receptor internalization through CCR7 …

Understanding Depressive Symptoms Among Emerging Adults, Salvador Dominguez

Open Access Theses & Dissertations

As societies have progressed following the industrial revolution, the transitioning into adulthood has undergone constant changes. This shift has resulted in young adults delaying traditional roles such as marriage and parenthood to pursue tertiary education and other opportunities. Emerging adulthood (ages 18-25) is a phase during an individual's life where they undergo constant changes because of newfound independence, new relationships, and other life-changing events. Currently, it has transitioned into a period where symptoms of depression are commonly experienced more than any other time in life. Given the negative impacts that depressive symptoms can have on individuals' well-being, two studies were …

The Role Of Map Kinase Phosphatase-5 In Cardiac Adaptations To Endurance Exercise, Jaime Alfredo Perales

Open Access Theses & Dissertations

Endurance Exercise is a form of exercise that provides many benefits to the human body. Primarily, the cardiac muscle endures many cardiac adaptations in response to Endurance Exercise. But the mechanisms that are involved within these adaptations remains to be fully understood. MAPK or mitogen-activated protein kinase is a well know signaling pathway that promotes many cardiac benefits such as cell proliferation, protein synthesis and cell differentiation. Although this pathway is activated due to its upstream kinase (MKKs), the research presented focuses on the relationship and mechanisms involved in mitogen kinase phosphatase (MKPs) specifically (MKP-5). The research presented hopes to …

Contribution Of A Higher Educational Institution Towards Advancing Sustainability In The West Texas Paso Del Norte Region, Anand Raj

Open Access Theses & Dissertations

Sustainability comprises primarily three elements; environmental, social, and economic, which can be considered the keys to humanityâ??s survival and wellbeing. The pillars can alternately be given informal names: planet, people, and profit. Sustainability is achieved by effectively utilizing available resources through different sustainable development efforts. Generally, groups or entities come together to create sustainable impact in the three primary elements discussed here. City councils, businesses, and higher education institutions are just a few of the entities that engage in sustainability efforts. It is valuable to appraise the role played by a higher education institution in advancing sustainability in the context …

Understanding Mental Health Related Factors And High-Risk Behaviors Among Emerging Adults Through The Lens Of The Social-Ecological Model, Sheralyn Sanchez

Open Access Theses & Dissertations

Emerging adulthood is a transitional period where young adults are faced with new challenges while exploring their identity and experimenting with life choices. However, during this time, young adults are more at risk of engaging in risky behaviors. The focus on emerging adults is important since the health and development of young adults can influence their health and life outcomes. The social-ecological model was used to understand the relationship between mental health and high-risk behaviors, in addition to the influence from different ecological factors (individual, relationship, and community). This study examined the relationship between the presence of mental health issues …

Berberine Remodels Adipose Tissue To Attenuate Metabolic Disorders By Activating Sirtuin 3, Dan Li, Chao Yang, Jian-Zhong Zhu, Eduardo Lopez, Tian Zhang, Qiang Tong, Cheng Peng, Li-Gen Lin

Faculty, Staff and Students Publications

Adipose tissue remodelling is considered a critical pathophysiological hallmark of obesity and related metabolic diseases. Berberine (BBR), a natural isoquinoline alkaloid, has potent anti-hyperlipidaemic and anti-hyperglycaemic effects. This study aimed to explore the role of BBR in modulating adipose tissue remodelling and the underlying mechanisms. BBR protected high fat diet (HFD)-fed mice against adiposity, insulin resistance and hyperlipidemia. BBR alleviated adipose tissue inflammation and fibrosis by inhibiting macrophage infiltration, pro-inflammatory macrophage polarization and the abnormal deposition of extracellular matrix, and the effect was mediated by BBR directly binding and activating the deacetylase Sirtuin 3 (SIRT3) and suppressing the activation of …

A D2 To D1 Shift In Dopaminergic Inputs To Midbrain 5-Ht Neurons Causes Anorexia In Mice, Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong Xu

Faculty, Staff and Students Publications

Midbrain dopamine (DA) and serotonin (5-HT) neurons regulate motivated behaviors, including feeding, but less is known about how these circuits may interact. In this study, we found that DA neurons in the mouse ventral tegmental area bidirectionally regulate the activity of 5-HT neurons in the dorsal raphe nucleus (DRN), with weaker stimulation causing DRD2-dependent inhibition and overeating, while stronger stimulation causing DRD1-dependent activation and anorexia. Furthermore, in the activity-based anorexia (ABA) paradigm, which is a mouse model mimicking some clinical features of human anorexia nervosa (AN), we observed a DRD2 to DRD1 shift of DA neurotransmission on 5-HT

Association Of Physical Activity, Sports, And Screen Time With Adolescent Behaviors In Youth Who Visit The Pediatric Emergency Department, Rohit P Shenoi, James G Linakis, Julie R Bromberg, T Charles Casper, Rachel Richards, Thomas H Chun, Victor M Gonzalez, Michael J Mello, Anthony Spirito

Faculty, Staff and Students Publications

Moderate to vigorous physical activity (MVPA), sports, and reduced screen time are associated with favorable youth risk profiles. We evaluated the association of MVPA, sports, and screen time with adolescent behaviors among pediatric emergency department youth. Adolescents were assessed for alcohol/drug use, risky behavior, conduct disorder, and depressive mood. MVPA was activity for ≥5 days/week and ≥60 minutes/day. Increased screen time was ≥3 hours/day computer/TV use for non-schoolwork. Multivariable regression studied association between MVPA, sports, and increased screen time and outcomes adjusting for demographics and academic achievement. Older age and lower academic achievement were significantly associated with risky behaviors, conduct …

Health-Related Quality Of Life In Pediatric Acute Recurrent Or Chronic Pancreatitis: Association With Biopsychosocial Risk Factors, See Wan Tham, Fuchenchu Wang, Cheryl E Gariepy, Gretchen A Cress, Maisam A Abu-El-Haija, Melena D Bellin, Kate M Ellery, Douglas S Fishman, Tanja Gonska, Melvin B Heyman, Tom K Lin, Asim Maqbool, Brian A Mcferron, Veronique D Morinville, Jaimie D Nathan, Chee Y Ooi, Emily R Perito, Sarah Jane Schwarzenberg, Zachary M Sellers, Uzma Shah, David M Troendle, Michael Wilschanski, Yuhua Zheng, Ying Yuan, Mark E Lowe, Aliye Uc, Tonya M Palermo, International Study Group Of Pediatric Pancreatitis: In Search For A Cure (Insppire) And Consortium For The Study Of Chronic Pancreatitis, Diabetes And Pancreatic Cancer (Cpdpc)

Faculty, Staff and Students Publications

OBJECTIVES: Abdominal pain, emergency department visits, and hospitalizations impact lives of children with acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP). Data on health-related quality of life (HRQOL) in this population, however, remains limited. We aimed to evaluate HRQOL in children with ARP or CP; and test biopsychosocial risk factors associated with low HRQOL.

METHODS: Data were acquired from the INternational Study Group of Pediatric Pancreatitis: In search for a cuRE registry. Baseline demographic and clinical questionnaires, the Child Health Questionnaire (measures HRQOL) and Child Behavior Checklist (measures emotional and behavioral functioning) were completed at enrollment.

RESULTS: The sample included …