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Healthcare Screenings In The Occupational And Workplace Setting: Taking Control Over Blood Pressure, Darryl W. Horton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Undiagnosed hypertension continues to be a growing concern worldwide leading to cardiovascular disease and other chronic illnesses and can contribute to death. The prevalence of hypertension continues to increase even with guidelines on screening, hypertension education, disease prevention, disease maintenance, and management. The purpose of this project was to determine if the implementation of a workplace blood pressure screening program would improve hypertension knowledge and reduce the burden of hypertension within workplace. A descriptive, cross-sectional design using convenience sampling was conducted. Participants were screened by measuring blood pressures, and the Hypertension Evaluation of Lifestyle Management scale (HELM) was utilized to …

Egypt’S Pediatric Oncology Hospital 57357: A Case Study Analysis, Ashley A. Clegg

Honors Program: Senior Projects (Public)

Hospital 57357 is the foremost pediatric oncology hospital in Egypt and provides treatment free of charge to children with cancer. Since its establishment in 2007, the hospital has grown to a capacity of 380 patient beds across three locations. Its quest for continuous improvement led to the development of a new performance management system emphasizing the tracking and measurement of a multitude of Key Performance Indicators across all departments. While this new system enables objective and perpetual monitoring of key patient care metrics, its integration into the existing structure introduces challenges that must be addressed. To analyze the external environment …

Impact Of School Lunches On Elementary School Students' Academics, Yudbeth Coronel

Capstone Projects and Master's Theses

The focus of this senior capstone is to analyze the impact of school lunches on elementary student’s academic performance. It is obvious to note that the nutrition a student consumes can have a huge impact on their academics; whereas students who do not, students who do not receive the correct number of calories per day may adversely have the opposite outcome during class time. The finding indicates that school lunches with a healthy diet could impact students’ academic performance as opposed to those unhealthy diets that could result in student’s poor academic achievement.

Benefits Of School Gardening Programs In Education: Opportunities And Challenges Towards Sustainability, Alyssa Conte

Capstone Projects and Master's Theses

The benefits of school gardening programs in education are numerous; yet, there is still no formal inclusion of these practices into the California State curriculum. Currently, school gardening programs are generated through community effort. The benefits of these programs are limited by their challenges, but when these programs are effective, they enhance the entire curriculum. This senior capstone study takes a look at what school gardening programs have done to be successful, and what benefits may be gained from further funding these programs. Through the use of qualitative research and interviews with local teachers along with CSUMB students, the results …

Calcium Intake Among Parents And Caregivers Of Children With A Milk Allergy Or Intolerance : A Comparative Analysis, Ilana Dubrovsky-Razam

Theses, Dissertations and Culminating Projects

Food allergies have become a global epidemic, affecting over 10% of the general population and 8% of children worldwide. Eliminating or limiting a food group from the diet can have adverse effects on micronutrient consumption. Milk allergies, for instance, can influence the amount of calcium consumed in the diet, particularly when limiting or excluding milk/milk-containing products from the diet. As milk products tend to be a primary source of dietary calcium, a milk allergy can serve as a barrier to meeting daily calcium needs.

Previous literature has analyzed the influence parents and caregivers have on their children’s diet, however, there …

Home Cooking Quality Assessment Tool Validation Using Community Science And Crowdsourcing Approaches, Margaret Raber, Nalini Ranjit, Larkin L Strong, Karen Basen-Engquist

Faculty, Staff and Student Publications

Objective: To refine a measure of home cooking quality (defined as the usage level of practices with the potential to influence the nutrient content of prepared foods) and conduct a construct validation of the revised tool, the Healthy Cooking Questionnaire 2 (HCQ2).

Design: Two validation approaches are described: (1) a community science approach used to refine and validate Healthy Cooking Questionnaire (HCQ) constructs, and (2) responses to the revised HCQ (HCQ2) in a sample of Amazon Mechanical Turk (MTurk) workers to determine questionnaire comprehension.

Setting: The Community Scientist Program at the University of Texas MD Anderson Cancer Center facilitated discussion …

Nonviral Approaches For Delivery Of Crispr-Cas9 Into Hepatocytes For Treatment Of Inherited Metabolic Disease, Tanner R. Rathbone

All Dissertations

Inherited metabolic diseases (IMDs) of the liver have a collective occurrence of about 1 in 800 births. Current therapies for IMDs of the liver are limited, and the only curative option for patients is orthotopic liver transplantation. Due to shortages of organ donors, immunosuppression following the transplantation, and mortality risks associated with the procedure, alternative treatment options are necessary for curing IMDs of the liver. Therapeutic gene editing has been proposed as a potential strategy for treating IMDs of the liver. Adeno-associated viral vectors (AAVs) are the most widely used delivery method for liver-targeted gene therapies. Although widely used for …

Developing Implantable Hydrogel-Based Sensors To Measure Biomarkers In Synovial Joint Fluid Using Plain Radiography, Uthpala N. Wijayaratna

All Dissertations

The goal of my dissertation research is to develop implantable sensors that attach to prosthesis prior to implantation and measures biomarkers of infection in joint fluid in order to detect, monitor, and study infection using plain radiography. Joint replacement surgeries are common procedures improving the mobility and lives of millions of people worldwide. Although the surgeries are generally successful, about 1% of prosthetic hips become infected. If the infections are not detected and treated promptly with antibiotics and surgical debridement, device removal is almost always required to treat the infections. Therefore, it’s important to detect post-surgery infections early and monitor …

Evaluation Of Grazing Techniques As A Nutrition Source For Horses In A Pasture Environment, Brittany Perron

All Dissertations

Horses require daily access to forage in order to support their gastrointestinal tract function as well as natural grazing behaviors. Well-managed pasture provides horses with a consistent forage source and diminishes health risks such as colic, ulcers and stereotypies. However, equine grazing behaviors are more intense than other livestock and may be detrimental to plant and soil health. A grazing management technique specifically for horses is necessary to prevent both health and environmental issues. The following dissertation explores both the movement of required maintenance elements, such as feed, shelter, and water, as well as the manipulation of feeding frequency and …

Essays On Economics Of The Family, Yinlin Dai

All Dissertations

In the first chapter, I explore the role of gender discrimination in children’s investments by parents. I specifically examine whether parents in urban China devote more household resources, specifically education, health, and total expenditures, to girls than to boys. The empirical literature has extensively examined trends in the sex ratio at birth and the effect of gender on the extensive margin of fertility. Much less of the existing literature has explored the impact of gender on the intensive margin of parental inputs mainly because of lack of individual child-level data, especially in urban China. This is an important area for …

Variations In Consumer Rejection Thresholds Of Water Samples Including Mixed-Berries Flavors, Kathryn Mccullough

Graduate Theses and Dissertations

Functional flavored water has emerged as a major space in the beverage industry in recent years. However, no research has explored the point that consumers begin to reject a specific flavor concentration within a flavored water matrix (i.e., a consumer rejection threshold). The first part of this thesis aimed to determine the consumer rejection thresholds of mixed-berry flavors in both sweetened and unsweetened water samples and examine the effects of demographics, food neophobia status, and personality traits on the consumer rejection thresholds. The second part of this thesis aimed to distinguish and compare consumer rejection threshold methodologies with and without …

Telling The Story: Diabetes Prevention And Management, Brandi Caitlyn Frizzell

Masters Theses

Diabetes has been studied for thousands of years, however the root cause of this disease is still unknown. Although there are have been many disoveries for treatment options for this disease, there has yet to be a discovery of a cure. Diabetes is a worldwide epidemic that currently affects millions of people and is expected to affect millions more in the future. This disease often results in fatal health complications which contribute to years of life lost and mortality rates. The project proposes a solution for individuals affected by diabetes and those that are currently undiagnosed. The expected outcome of …

Phytochemical And Synthetic Ahr Ligands As Novel Therapy For Refractory Breast Cancer, Jonathan V. Wooten

Loma Linda University Electronic Theses, Dissertations & Projects

Patients with triple-negative breast cancer (TNBC) possess tumors that lack estrogen receptor, progesterone receptor, and human growth factor receptor 2 expression. Such patients have lower survival rates than those diagnosed with other breast cancer subtypes in part, due to the scarcity of targeted therapy for TNBC. In addition to chemotherapy, patients with TNBC often consume natural remedies, which has led us and others to evaluate the ability of plant isolates to confer anticancer and chemopreventive actions. Poly-ADP ribose polymerase (PARP) is an enzyme that promotes DNA single-strand break repair. PARP inhibitor olaparib exploits DNA repair enzyme deficiency in tumors to …

Impact Of Delaying Irrigation On Wilting, Seed Yield, And Other Agronomic Traits Of Determinate Mg5 Soybean, Francia Ravelombola, Andrea Acuna, Liliana Florez-Palacios, Chengjun Wu, Derrick Harrison, Maria De Oliveira, Joshua Winter, Marcos Da Silva, Trenton Roberts, Christopher Henry, Fernando Grignola, Ehsanollah Shakiba, Leandro Mozzoni

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Soybean production in the U.S. Mid-South relies heavily on irrigation with 85% of soybean surfaces irrigated in Arkansas. Reduction in irrigation due to water quantity restrictions will significantly affect soybean seed yield, making variety selection increasingly important. The objective of the study was to assess if irrigation onsets at different reproductive stages affect wilting, seed yield, and key agronomic traits on determinate maturity group 5 (MG 5) soybean. One-hundred sixty-five F₄-derived populations of recombinant inbred lines with determinate growth habit, similar maturity, and contrasting wilting potential were planted in an augmented strip-plot design in four environments as a …

The Occupational Therapy Approach To Pain Treatment: A Pain Curriculum, Rosalee Howell

UNLV Theses, Dissertations, Professional Papers, and Capstones

It is within the scope of the occupational therapy profession to treat patients experiencing pain. The holistic approach used to assess and treat patients to improve functional performance is vital in treating pain. The focus is to decrease the detrimental impact of pain on the patient’s mental health, enhancing their ability to function in social and vocational roles. However, education is not adequately addressed in occupational therapy programs and is vital in preparing clinicians to meet the patient’s needs effectively.

This Doctoral Capstone was developed to highlight the importance and the benefit of education in preparing clinicians to treat patients …

A Wearable Electronic Monitoring Device For Low Pressure Garment Applications And Temperature Analysis For Prevention Of Ulceration And Infection, Francisco Mata Carlos

UNLV Theses, Dissertations, Professional Papers, and Capstones

The healing process of several medical conditions related to venous insufficiency and burn scar management can be improved by the proper application of pressure. Current practices for applying pressure to an extremity do not guarantee the consensus ideal interface pressures for such medical conditions. Applying a low pressure range (within 15 – 40 mm Hg) is challenging due to many factors, but especially because the actual pressure applied by a compression garment used on a patient is unknown. The proposed device, used to sense and display low pressure values, is described in detail throughout the chapters of this thesis.An electronic …

The Effects Of Transcranial Direct Current Stimulation On Motor Learning In Complex Motor Tasks, Milan Pantovic

UNLV Theses, Dissertations, Professional Papers, and Capstones

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has emerged over the past 10-12 years as safe, affordable, portable, easy to use, and potentially efficacious adjuvant training intervention in several aspects of human performance. tDCS has been shown to be able to improve both cognitive and motor function in a wide variety of populations such as young adults, older adults, stroke, Parkinson’s disease, and many others. However, the majority of tDCS research has been conducted in the motor system of healthy young adults, which will also be the focus of this dissertation.The basic effects of tDCS …

Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Diabetic peripheral neuropathy is one of the common complications of type-2 diabetes mellitus (DM). Changes in the intrinsic plantar tissue coupled with repetitive mechanical loads and loss of sensation may lead to foot related complications (skin break down, ulcerations, and amputations) in persons with neuropathy if left untreated. The purpose of this dissertation was to stratify individuals with pre-diabetes, diabetes with and without neuropathy using dynamic plantar pressure parameters during walking, using machine learning algorithms.Methods: Plantar pressure data was collected from one hundred participants during walking with pressure measuring insoles fixed between the feet and thin socks. Simultaneously high-definition …

Investigating The Impact Of Hypoxia On Reactive Oxygen Species Generation Within Murine Breast Cancer Cells, Jared Mcpeake

Biomedical Engineering Undergraduate Honors Theses

When cancer metastasizes from a primary tumor site to secondary site through the bloodstream or lymph, the cancer becomes more difficult to treat. For this reason, it is vital to study what indicates the metastatic potential of a tumor. Current research has shown that cell lines with high metastatic potential display increased levels of metabolic adaptability over their nonmetastatic counterparts after undergoing hypoxic conditions. One method of assessing this adaptability is to measure the concentration of reactive oxygen species (ROS) produced by the cells while undergoing oxidative stress. In highly adaptable metastatic cells, an increase of ROS buildup within the …

Effects Of A Leucine Supplementation On Mitochondrial Markers In Pre-Cachectic Female Mice, Breanna Williams

Biological Sciences Undergraduate Honors Theses

Cancer cachexia is a wasting syndrome characterized by extreme weight and skeletal muscle loss that results in death in many tumor bearing individuals. Because skeletal muscle requires a high amount of energy to function, skeletal muscle fiber cells need healthy mitochondria to function. When skeletal muscle loss atrophy occurs, the mitochondrial network is degraded. Different treatments for this muscle atrophy are being studied, one of which is a leucine supplementation since leucine has been found to stimulate skeletal muscle growth in other studies. However, current data suggests that a leucine supplementation in cachexic individuals exacerbates this atrophy. PURPOSE: This study …

The Effects Of Time Restricted Feeding On Markers Of Type 2 Diabetes, Brooke Martin

Biological Sciences Undergraduate Honors Theses

Type 2 diabetes is one of the fastest growing chronic diseases in the country, comprising 10% of the American population. Obesity rates are at an all-time high and greatly increase risk factors for developing diabetes. Insulin resistance is the main feature of type 2 diabetes and causes management of the disease to be extremely difficult. Currently there are different possible treatments for type 2 diabetes including medication and dieting. However, diets involving fasting, though high in popularity, do not have a lot of evidence regarding their ability to prevent the development of type 2 diabetes.

Time restricted feeding (TRF) is …

Utilizing A Themed Workbook To Capture Insights To Young Women In Science, Technology, Engineering, Arts, And Mathematics (Steam/Stem) Using The Internet Of Things (Iot), Systems Engineering, And Data Science, Robert John Konczynski Jr.

Theses and Dissertations

Young women may not realize that many of their cell phones, computers, TVs, cars, airplanes, and the technology around them, for the most part, have been designed by men. Men have been fundamental in designing these devices because women only account for a quarter of the workers in STEAM jobs. Because many women choose jobs and careers unrelated to STEAM, they are not part of the inclusive design and Engineering efforts that go into today’s products and technology. Given the underrepresentation of women as part of the design phase of Science, Technology, Engineering, Arts, and Mathematics, society is missing out …

Assessing Nutritional Health Knowledge In Sharing Clinic Patients With Diabetes, Minden Huntrods

Capstone Experience: Master of Public Health

Effective diabetes prevention and management relies on nutritional behaviors, thus a basic level of health knowledge is important for patients with diabetes and their caregivers in their quest to acquire acute glycemic control and minimize negative health outcomes (Ley et al., 2014). The purpose of this study was to assess the nutrition-related health knowledge of patients living with diabetes who are seen at the UNMC Sharing Clinic by use of a verbal questionnaire. This nutritional health knowledge assessment was a quantitative, prospective, survey-based study utilizing descriptive statistics. Approximately 86% of patients were proficient in food group and nutritious foods knowledge …

The Art Of Nutrition, Kylanna Hardaway

Human Nutrition and Hospitality Management Undergraduate Honors Theses

Many colleges and universities offer students access to on-campus food pantries, yet very few students utilize these services despite reporting high rates of food insecurity. Considering the importance of a healthy diet on the developing minds of young adults, it is pertinent that colleges and universities find innovative ways to reach food insecure students. The purpose of this hybrid creative-research project was to creatively address commonly cited barriers of seeking food assistance (i.e., negative stigma, embarrassment, unknown location, awareness of resource, etc.) using public art. A mural was designed to encourage healthy eating behaviors and provide signage for the Jane …

Exploring The Role Of Metabolites In Cancer And The Associated Nerve Crosstalk, Inah Gu, Emory A. Gregory, Casey Atwood, Sun-Ok Lee, Young Hye Song

Biomedical Engineering Faculty Publications and Presentations

Since Otto Warburg's first report on the increased uptake of glucose and lactate release by cancer cells, dysregulated metabolism has been acknowledged as a hallmark of cancer that promotes proliferation and metastasis. Over the last century, studies have shown that cancer metabolism is complex, and by-products of glucose and glutamine catabolism induce a cascade of both pro- and antitumorigenic processes. Some vitamins, which have traditionally been praised for preventing and inhibiting the proliferation of cancer cells, have also been proven to cause cancer progression in a dose-dependent manner. Importantly, recent findings have shown that the nervous system is a key …

Biomarkers And Factors Related To Risk Of Acute Kidney Injury, Mary Ann David

Dissertations

Background: Acute kidney injury (AKI) is associated with increased mortality, morbidity, length of hospital stay, and in-hospital cost. Timely intervention is needed to prevent disease progression, but the delay in diagnostic process often results in delayed treatment. Recent studies show a significant increase in novel urine biomarkers (UB), TIMP-2 and IGFBP7, has been linked to an increased risk of AKI.

Objectives: The purpose of this study was to examine the relationships among participants’ sociodemographic and clinical characteristics, including select biomarkers, care management processes, treatments, and patient outcomes in a sample of hospitalized critically ill patients in southern California.

Findings: Study …

Multiple Metals In Children’S Deciduous Teeth: Results From A Community-Initiated Pilot Study, Alexa Friedman, Julia Anglen Bauer, Christine Austin, Timothy Downs, Yorghos Tripodis, Wendy Heiger-Bernays, Roberta White, Manish Arora, Birgit Claus Henn

Sustainability and Social Justice

Background: Characterizing retrospective exposure to toxicants during multiple early-life developmental periods is challenging, yet critical for understanding developmental effects. Objective: To characterize early-life metal exposure using deciduous teeth in a community concerned about past exposures. Methods: Naturally shed teeth were collected from 30 children ages 5–13 years who resided in Holliston, Massachusetts since conception. We estimated weekly prenatal and postnatal (up to 1 year of age) exposure to 12 metals by measuring dentine concentrations using laser ablation-inductively coupled plasma-mass spectrometry. Multivariable linear mixed models were used to explore sociodemographic, dietary, and behavioral correlates of dentine metal concentrations. Results: Temporal trends …

Perceived Benefits Of Upskilling And Reskilling By Persons Who Are Among The Employed, Underemployed, And Unemployed, Rosalind Marie Evans

Electronic Theses and Dissertations

ABSTRACT The purpose of this research study is to explore the perceived influence, potential impact, and benefits that upskilling, and reskilling have on the employed, underemployed, and unemployed worker. In addition, this study seeks to explore whether the perceived benefits of upskilling and reskilling include moving above the poverty line and therefore, out of poverty in real and sustainable ways. This resulting new position and potential increase in pay could have the positive impact of moving them and their families above the poverty line. The results of this study indicate that participants perceive upskilling and reskilling to be an option …

Creation Care, Human Wellness, And Sustainability, Omoike Eric Aizenofe

Electronic Theses and Dissertations

In this thesis, I argue that creation care contributes to human wellness and to sustainable living on earth. Within contemporary contexts, humans are suffering spiritually, mentally, and emotionally. This distress impairs wellness and reduces peoples’ capacity to contribute to sustainable solutions and earth-positive impacts. Creation care entails conscious and intentional activities that are carried out for the health of the created world. Creation care contributes to human wellness, spiritually, mentally, and emotionally by offering spaces, environments, co-habitations, and interdependency among its components that support human wellness and sustainable living. Creation care helps fight spiritual, mental, and emotional distress so that …

The Experience Of Music Therapists Working With The Parents Of Premature Infants In The Neonatal Intensive Care Unit (Nicu), Harria Kim

Theses & Dissertations

This study explored the lived experience of music therapists working with parents of premature infants in the neonatal intensive care unit (NICU). While there are many studies regarding the effects of music therapy on parents and premature infants in the NICU, few in-depth qualitative studies focus on the experiences and perspectives of music therapists working in the NICU. The present study aims to explore music therapists’ experiences of working with the parents of premature infants in the NICU and their perspectives on how music therapy can meet the needs of these parents. Data were collected through audio-video recording and transcription …