Digital Commons Network^™

Examining Relationships Between Sediment Nutrients And Halodule Wrightii In The Southern Indian River Lagoon, Sarah Newton

Electronic Theses and Dissertations 2020 - Present

In the Indian River Lagoon (IRL), FL, seagrasses have declined 58% since 2009, largely due to eutrophication. Efforts to improve IRL water quality are ongoing, but there has been a lag in seagrass recovery, with Halodule wrightii being the focus of restoration efforts. Because seagrasses uptake nutrients through their rhizomes and blades, this lag may be associated with undocumented pore water nutrient pollution. Thus, deciphering relationships between sediment nutrients and H. wrightii is necessary. In this study, sampling at nine sites in the southern IRL (SIRL) was conducted in spring and summer 2024 during which H. wrightii tissue, sediment, and …

Wellness Among Bipoc Counselors-In-Training: Mediation Impact On Stress And Burnout, Javier E. Ponce

Electronic Theses and Dissertations 2020 - Present

The purpose of this research study was to gather data on stress, wellness, and burnout levels from counselors-in-training (CITs) who identify as Black, Indigenous, and people of color (BIPOC) to compare them to norm groups and assess the mediating effect of wellness on the association between stress and burnout. The researcher conducted this study to aid counselor educators in incorporating wellness into interventions that can help BIPOC CITs not only reduce their stress and burnout levels but also augment their overall wellness. The final sample consisted of 118 BIPOC CITs who thoroughly completed a demographic questionnaire, Perceived Stress Scale-10, Five …

Exploring Undergraduate Students’ Use Of Mental Health Applications: A Phenomenological Study, Chelsea D. Fullilove

Electronic Theses and Dissertations 2020 - Present

This phenomenological dissertation explored undergraduate students' lived experiences of using mental health mobile apps, AI, and other technology to manage mental health symptoms. The research focused on exploring three research questions: (a) perceptions of app effectiveness, usability, and features; (b) barriers and integration into mental health care routines; and (c) influences of privacy, peer influence, cultural backgrounds, and personal beliefs on app use.

Data were collected via purposive sampling through semi-structured interviews (N=12), each consisting of 15 open-ended questions, with students using a mental health app to improve their mental health. The interpretive data analysis was conducted by …

Exploring Mindfulness, Mindful Self-Care, And Perceived Burnout Among Professional Counselors: A Latent Profile Analysis, Sheria Kwok

Electronic Theses and Dissertations 2020 - Present

Promoting counselor well-being and burnout prevention through research efforts is necessary. This study explored the findings (emerging unobserved profiles) from a latent profile analysis (LPA) examining mindfulness, mindful self-care behaviors, and perceived burnout among licensed professional counselors and supervisors in Ohio (N = 328). The study evaluated the differences in individual demographic variables across the identified latent profile memberships derived from the LPA. As a result, we found two latent profile memberships: Low Mindfulness/Mindful Self-Care and High Burnout Group (n = 146; 44.5%), and High Mindfulness/Mindful Self-Care and Low Burnout Group (n = 182; 55.5%). Based …

Multiscale Modeling Of Infectious Diseases: Identifiability Framework For Parameter Estimation And Model Validation, Ambegoda Liyanage

Electronic Theses and Dissertations 2020 - Present

Understanding and controlling the spread of infectious diseases requires integrative mathematical models that connect biological processes across multiple scales, from individual-level transmission dynamics to population-level epidemic behavior. In this work, we develop and analyze multiscale mathematical models to investigate the transmission of emerging and re-emerging infectious diseases, with a strong focus on structural and practical identifiability to ensure model reliability.

We begin by investigating the transmission dynamics of the Usutu virus (USUV), an emerging mosquito-borne virus of growing concern in Europe and Africa. Understanding the epidemiology of such pathogens requires a systems-level approach that captures biological processes across multiple scales, …

Daily Movement Activities Are Associated With Within-Person Instability Of Cognitive Function In Older Adults: Evidence From An Ambulatory Assessment Study, Chih-Hsiang Yang, Donald Hedeker, Jongwon Lee, Halle Prine, Donna Coffman, Jingkai Wei, Jonathan George Hakun

Faculty, Staff and Student Publications

Background and objectives: Physical inactivity and excessive sedentary time (ST) are associated with poor cognitive health in older adults. However, current literature largely relies on cross-sectional designs or in-lab cognitive assessments, which do not adequately reflect cognitive function in naturalistic settings. Further, existing studies have largely overlooked the variability or the instability in daily cognitive function, which represents a critical marker of cognitive decline. This ambulatory assessment study examined the temporal associations of daily movement behaviors with the mean levels and the variability of cognition among older adults at risk of dementia.

Research design and methods: 96 older adults from …

Parent And Family Guide, 2025-2026, Illinois State University, Dean Of Students Office, Parent And Family Services

Parent and Family Guide

Campus guide prepared by the Illinois State University Dean of Students Office's Parent and Family Services Department

Parent & Family Newsletter, May 2025, Illinois State University, Parent And Family Services

Parent & Family Newsletter

Parent and Family Newsletter

Parent & Family Newsletter, February 2025, Illinois State University, Parent And Family Services

Parent & Family Newsletter

Parent and Family Newsletter

A Novel D-Peptide Modulates Dclk1 Gelsolin Interactions, Reducing Pdac Tumor Growth, Landon L. Moore, Dongfeng Qu, Parthasarathy Chandrekesan, Kamille Pitts, Randal May, Byron E. Anderson, Milton L. Brown, Courtney W. Houchen

Department of Medicine Faculty Publications

What drives inflammation-associated tumorigenesis and progression in pancreatic ductal adenocarcinoma (PDAC)? Doublecortin-like kinase 1 (DCLK1) is a central driver of inflammation-associated tumorigenesis, with elevated expression linked to worse clinical outcomes. Two isoforms of DCLK1 possess a unique extracellular domain (ECD). DCLK1 isoform 2 contains two microtubule-binding domains, while isoform 4, lacks the microtubule-binding domains but, plays a pivotal role in tumor progression. We identified novel D-peptides that selectively target this ECD, significantly suppressing PDAC cell proliferation in vitro and tumor growth in xenograft models without inducing cell death. In silico modeling and binding assays revealed DCLK1 isoform 4 interacts with …

Exploring The Role Of 5-Hydroxymethyl-2-Furfural And Sumiki's Acid In Beta-Cell Metabolism, Daiwik Munjwani, Demitrius Hill, David Regan, David Lee, Mike Muehlbauer, Hans-Ewald Hohmeier, Mette Jensen, Neolle E. Younge, James Bain

Department of Medicine Faculty Publications

Type 1 diabetes (T1D), a leading cause of mortality in the United States, is associated with heart disease, nephropathy, neuropathy, retinopathy, and stroke. While management of T1D with medications and healthy lifestyle choices is critical, recent research highlights the contributory role of environmental diabetogens in the pathogenesis of T1D. Here, we propose that the furan compound, 5-hydroxymethyl-2-furfural (HMF), which forms when hexoses such as glucose or fructose lose three water molecules during thermal food processing, might be an unrecognized dietary diabetogen. HMF is a suspected mutagen and carcinogen. In a previous experiment in the rat 832/13 beta-cell line, when cultures …

Multisociety Guidance For Infection Prevention And Control In Nursing Homes, Lona Mody, Sonali D. Advani, Muhammad Salman Ashraf, Allison H. Bartlett, Suzanne F. Bradley, Deborah P. Burdsall, Jennifer A. Hanrahan, Susan S. Huang, Robert L.P. Jump, Lindsay Nicolle, Mary-Claire Roghmann, Patricia Stone, Rekha K. Murthy

Department of Medicine Faculty Publications

This multisociety guidance was endorsed by SHEA, APIC, IDSA, PALTmed, and AGS. It provides recommendations for infection prevention and control (IPC) in the context of the complexity of nursing home care in the United States: increased medical acuity of residents, the spread of multidrug-resistant organisms, and the threat of emerging pathogens. Recommendations and implementation suggestions address IPC leadership, staffing, and resources, healthcare personnel and residents‘ adherence to precautions and effective hand hygiene, outbreak preparedness, training, occupational health, cleaning and disinfection in the care environment, and the involvement of IPC in the facility. The guidance also addresses the challenges of maintaining …

Parenteral Nutritional Support In Surgical Patients: Expert Consensus Statements Regarding Intravenous Lipid Emulsions Containing Omega-3 Fatty Acids., Robert G Martindale, David C Evans, Dan Waitzberg, Malissa Warren, Manpreet S Mundi, Stanislaw Klek, Paul E Wischmeyer, Martin D Rosenthal

Surgery Articles

OBJECTIVES: The International Lipids in Parenteral Nutrition (PN) Summit was convened to offer practical guidance and expert consensus opinion regarding the use of intravenous lipid emulsions (ILEs) in various clinical settings. Herein, we briefly review aspects from this summit that are of particular importance for surgical/hospitalized patients.

METHODS: Summit participants identified and discussed new evidence, data, and analyses, that potentially influence the benefits and risks of ILEs in PN or their use in clinical practice. The summit meeting consisted of expert presentations that assessed recent clinical data and best practice, followed by periodic panel discussions to formulate consensus statements. Consensus …

Predictive Modeling For Healthcare Data Using Nonlinear Bayesian Methods, Prince Kofi Asare

Theses and Dissertations

Unplanned hospital readmissions represent a significant challenge for healthcare systems, contributing to substantial financial burdens and highlighting gaps in patient care coordination. In the U.S., approximately 20% of Medicare beneficiaries are readmitted within 30 days, costing billions annually. Social determinants of health, such as income, housing stability, and social support, account for up to 80% of health outcomes, yet their integration into predictive models remains underexplored. This study introduces a novel Bayesian framework for predicting 30-day readmission risk, combining Gaussian Process models with spike-and-slab priors and Bayesian Lasso regression with Laplace priors. Utilizing Markov Chain Monte Carlo methods, the approach …

Exploring Childcare Leaders’ Perspectives On Program Philosophies At The Intersection Of Care, Education, And Business: A Multi-Method (Qual + Qual) Study Using Simon Sinek’S Golden Circle, Megan Kybartas

Theses and Dissertations

This multi-method (QUAL + qual) study explores childcare leaders’ perspectives on program philosophies at the intersection of care, education, and business, which I call The Childcare Tripartite. Recognizing the significant dependency on high-quality childcare services and the foundational role of program philosophies in achieving this quality, this research addresses a notable gap in the literature regarding how early childhood leaders communicate and prioritize their program philosophies within the complex American childcare landscape. Employing semi-structured interviews, documentary materials, and demographic forms, and analyzed through both thematic and deductive content analysis, drawing on Simon Sinek’s Golden Circle, the study uncovers how philosophical …

Converting Cover Crop Biomass To Biogas And Volatile Fatty Acids, Tuba Yasmin Lubna

Theses and Dissertations

Cover crops are commonly used for their environmental benefits, including improved soil health and reduced soil erosion. However, there is limited use for the aboveground biomass, except for oilseed crops. The objectives of this study were to (1) characterize the selected winter cover crop biomass at three growth stages, (2) evaluate the biogas and volatile fatty acids (VFAs) yield, and (3) examine the concurrent alkali pretreatment and ensiling effects on biogas yield. Wild pennycress, golden pennycress, CoverCress^TM, annual ryegrass, cereal rye, pea, and clover biomass were harvested at three growth stages. Results showed that biogas yield increased with …

American Society For Gastrointestinal Endoscopy Guideline On Gastrostomy Feeding Tubes: Methodology And Review Of Evidence, Divyanshoo Rai Kohli, Natalie Cosgrove, Wasif M Abidi, Jorge D Machicado, Madhav Desai, Nauzer Forbes, Neil B Marya, Nikhil R Thiruvengadam, Nirav C Thosani, Omeed Alipour, Saowanee Ngamruengphong, Sherif E Elhanafi, Sunil G Sheth, Wenly Ruan, John C Fang, Stephen A Mcclave, Rodrick C Zvavanjanja, Dhruvil K Radadiya, Amir Y Kamel, Bashar J Qumseya

Faculty, Staff and Student Publications

This article from the American Society for Gastrointestinal Endoscopy (ASGE) provides a full description of the methodology used to inform the final guidance outlined in the accompanying summary and recommendations article for strategies to manage endoscopically placed gastrostomy tubes. This article was developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework and specifically addresses the utility of PEG versus interventional radiology-guided gastrostomy (IR-G), the need for withholding antiplatelet and anticoagulant medications, appropriate timing to initiate tube feedings, and appropriate selection of the gastrostomy technique in patients with malignant dysphagia. In patients needing enteral access, the ASGE suggests …

Radiographic Axial Spondyloarthritis (Ankylosing Spondylitis) Commencing Late In Life, Mark C Hwang, Karim Doughem, Minjae Lee, Lianne S Gensler, Mariko L Ishimori, Michael M Ward, Matthew A Brown, Amirali Tahanan, Michael H Weisman, Mohammad H Rahbar, John D Reveille

Faculty, Staff and Student Publications

No abstract provided.

Use Of Hookah And Age Of Asthma Onset Among Us Adults, Adriana Pérez, Sarah Valencia, Pushan P Jani, Melissa B Harrell

Faculty, Staff and Student Publications

Objective: To explore the association of hookah use on the age of asthma onset among adults who were asthma/COPD free and who did not use cigarettes, cigars, electronic cigarettes or smokeless tobacco prior to asthma onset.

Methods: Secondary data analyses were conducted of the waves 1-6 (2013-2021) of the US nationally representative Population Assessment of Tobacco and Health Study among adults (>18 years). The four hookahs use exposures evaluated were (1) past 30-day (P30D) hookah use at the first wave of participation, (2) total number of waves before asthma onset in which adults reported P30D hookah use, (3) total …

An Ontology-Based Method For Formalizing And Encoding Patient Colonoscopy Preparation Using Bpmn And Owl2 For Automated Tool Development, Muhammad Amith, Yue Yu, Yuheng Shi, Brooks Cash, Barani Mayilvaganan, Anirudh Babu, Yang Gong

Faculty, Staff and Student Publications

Colonoscopy is a proven procedure for mitigating the incidence of colorectal cancers in late adulthood. Despite its effectiveness, colonoscopy preparation presents several challenges for patients, including issues with adherence and misunderstanding. Information and communication technology (ICT) tools may offer valuable support for modern patients. To enable such tools, computable knowledge bases are essential. In this paper, we describe the development of an ontology-based knowledge graph representing four laxative-based pre-colonoscopy procedures. We used the business process modeling and notation and OWL2 formalisms to manifest machine-readable artifacts that model processes of colonoscopy preparation. Future work will focus on integrating extended knowledge bases …

Oral Microbiome Brain Axis And Cognitive Performance In Older Adults, Darbaz Adnan, Phillip A Engen, Michelle Villanueva, Shohreh Raeisi, Vivian Ramirez, Ankur Naqib, Stefan J Green, Faraz Bishehsari, Lisa L Barnes, Ali Keshavarzian, Klodian Dhana, Robin M Voigt

Faculty, Staff and Student Publications

The human oral microbiota is a community of microorganisms that reside in the oral cavity, including lingual, buccal, and saliva, each niche with a distinct microbial composition. Alterations in oral microbiota have been associated with an increased risk of Alzheimer’s disease (AD). This study used data from 143 older adults in the MIND trial to evaluate the association between oral microbiome and cognitive function. Oral niche-specific differences (saliva, buccal, and lingual), as well as the microbiome composition differences (α and β diversity), were associated with cognitive function. A lower abundance of Gemella and a higher abundance of anaerobic pro-inflammatory bacteria …

Revisiting Cytomegalovirus In Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: Current Strategies For Prevention And Management In The Letermovir Era, Lisa Hiskey, Diego R Hijano, Ramia Zakhour

Faculty, Staff and Student Publications

CMV infection remains the most common clinically significant infection in pediatric allogeneic hematopoietic stem cell (HCT) recipients, with seropositive recipients of transplants from seronegative donors at the highest risk for complications. In recent years, letermovir, a novel antiviral with a favorable toxicity profile, was approved first for adults and more recently for pediatric patients for the primary prophylaxis of CMV infection and disease in high-risk HCT recipients. Growing evidence from real-life data regarding the safety and efficacy of letermovir has transformed the landscape of CMV disease in HCT transplant recipients and led to a paradigm shift from a preemptive approach …

Faktor Risiko Kejadian Hipertensi Dalam Kehamilan Pada Ibu Hamil Di Provinsi Jawa Timur (Analisis Data Riset Kesehatan Dasar Tahun 2018), Putri Amalia Firjatillah, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Hypertension during pregnancy is one of the most common pregnancy complications and the leading cause of maternal mortality in Indonesia. One of the regions in Indonesia with a high number of hypertension-related pregnancy complications is East-Java Province with a prevalence rate of 17,8%. This study aims to analyze the risk factors associated with hypertension during pregnancy among pregnant women in East Java. The study adopts a cross-sectional design using secondary data from 758 pregnant women aged 15-54 years in East Java Province who participated in 2018 Riskesdas Survey during which blood pressure measurements were taken. The dependent variable analyzed in …

Determinan Faktor Dengan Ketidakpatuhan Dalam Mengonsumsi Obat Antiretroviral Pada Orang Dengan Hiv(Odhiv) Di Rumah Sakit Umum Daerah Kabupaten Tangerang Tahun 2023, Dessi Marantika Nilam Sari, Mondastri Korib Sudaryo, Syahrizal Syarif, Helwiah Umniyati, Suyono .

Jurnal Epidemiologi Kesehatan Indonesia

Ketidakpatuhan alasan utama Pasien HIV tidak menerima pengobatan ARV sehingga harus selalu dipantau dan dinilai secara teratur serta didorong pada setiap kunjungan. Penelitian ini bertujuan untuk mengamati determinan faktor terjadinya ketidakpatuhan dalam mengonsumsi obat ARV pada ODHIV yang mendapatkan terapi ARV di Rumah Sakit Umum Daerah Kabupaten Tangerang. Jenis penelitian ini menggunakan penelitian observasional dengan rancangan cross sectional. Penelitian dilakukan di poli HIV RSUD Kabupaten pada bulan November 2023 menggunakan data laporan HIV pada SIHA. Populasi penelitian berjumlah 1.337 ODHIV aktif menjalani pengobatan antiretroviral di RSUD Kabupaten Tangerang dengan menggunakan total sampling sesuai dengan kriteria inklusi dan ekslusi sehingga sampel …

The Changes In Health-Related Quality Of Life After Attending Cardiac Rehabilitation: A Qualitative Systematic Review Of The Perspective Of Patients Living With Heart Disease, Amineh Rashidi, Lisa Whitehead, Helena Halton, Lisa Munro, Ian Jones, Lisa Newson

Research outputs 2022 to 2026

Background Although the benefits of engaging in cardiac rehabilitation are well established, patient perceptions of the changes in their health-related quality of life are poorly documented. This systematic review synthesized qualitative studies on patients’ perspectives of change in their health-related quality of life after attending cardiac rehabilitation. Objective To identify and synthesize the best available evidence on the perspective of patients living with heart disease about the changes in their health-related quality of life after attending cardiac rehabilitation. Methods Eight databases were used to identify relevant papers published in English and peer-reviewed, and no date restrictions were considered for the …

Associations Between Flavonoid-Rich Food And Flavonoid Intakes And Incident Unhealthy Aging Outcomes In Older United States Males And Females, Nicola P. Bondonno, Yan Lydia Liu, Francine Grodstein, Eric B. Rimm, Aedín Cassidy

Research outputs 2022 to 2026

Background: Our knowledge of the importance of flavonoid-rich foods in preventing unhealthy aging across its different domains is limited. Objectives: This study aimed to examine prospective associations between flavonoid-rich food and flavonoid intakes and indicators of unhealthy aging, namely frailty, impaired physical function, and poor mental health. Methods: We followed up 62,743 females and 23,687 males, all aged ≥60 y, from the Nurses’ Health Study (1990–2014) and Health Professionals Follow-up Study (2006–2018), respectively. Both time-updated and change in intakes of a flavodiet score (an aggregate of intakes of major flavonoid-rich foods and beverages) and individual flavonoid-rich foods and beverages and …

Good Arts, Good Mental Health®: The Effectiveness Of An Australian Health Promotion Media Campaign In Promoting Community Mental Wellbeing Via The Arts, Christina R. Davies, Melanie T. Pescud, Rhonda Clifford, Richard Mcgrath, Annie Thomson, Mia Jeffrey, Melissa Stoneham, Terri Pikora, Peter Wright, Sonya Girdler, Loretta Baldassar, Stephen Clift

Research outputs 2022 to 2026

Introduction: This study describes and evaluates Good Arts, Good Mental Health^® (GAGMH), a groundbreaking, population-level, arts-mental health promotion media campaign. The objectives of the campaign (Wave 1) were to increase brand awareness, comprehension, and agreement with the tagline Good Arts, Good Mental Health^® and empower the general population to form an intention to engage in the Arts for their mental wellbeing. Methods: The campaign ran from August to September 2024 (4 weeks), cost AUD$198,965 (23% creative and 77% media/advertising distribution), and targeted the Western Australian (WA) general population aged 18–65 years, all genders, in both metropolitan and regional …

Postharvest Aqueous Ozonation Alleviates Chilling Injury By Upregulating Ascorbate-Glutathione (Asa-Gsh) Cycle And Associated Antioxidant Enzymes In Cold-Stored ‘Kensington Pride’ Mango Fruit, Mekhala Dinushi Kananke Vithana, Mahmood Ul Hasan, Hafiz Muhammad Shoaib Shah, Zora Singh

Research outputs 2022 to 2026

Chilling injury (CI) hinders prolonged cold storage of mangoes (Mangifera indica L.). Hence, the influence of postharvest aqueous ozonation (PAO) (1 mg ozone s^{− 1}) of mature green ‘Kensington Pride’ mangoes for 10, 20 and 30 min preceding storage at 5 °C for 21 and 28 d on modulating CI, cell membrane integrity, ascorbate-glutathione (AsA-GSH) cycle, antioxidant enzymes and fruit quality were investigated. Compared to control, 10 min PAO significantly reduced CI index (62.5% and 42.9%), CI incidence (40.5% and 41.4%), weight loss (18.4% and 21.8%) and malondialdehyde (MDA) in peel (61.8% and 71.7%) in 21 and 28 …

Establishment Of Reference Intervals For Serum Immunoglobulin G N-Glycosylation Features In Healthy Chinese Adults: A Nationwide Survey In The Framework Of Predictive, Preventive, And Personalized Medicine, Changyu Liu, Yinghao Wang, Xingang Li, Xiaojia Xu, Ruirui Xu, Cuihong Tian, Zhixian Chen, Xinxia Lu, Yuejin Li, Meng Wang, Zhaoyang Tang, Xueyu Chen, Guoyong Ding, Xuerui Tan, Dong Li, Haifeng Hou, Wei Wang

Research outputs 2022 to 2026

Background: Immunoglobulin G (IgG) N-glycosylation plays a vital role in the pathogenesis of autoimmune disorders, inflammatory diseases, and viral infections. While various models of serum IgG N-glycosylation have been developed to identify individuals at high risk for relevant diseases, reference intervals (RIs) for the levels of IgG N-glycans have not been established yet. Identifying RIs for serum IgG N-glycans closely associated with biological aging and disease risk contributes to predictive, preventive, and personalized medicine (PPPM/3PM), which results in improvement of patients’ outcomes, enhancement of healthcare efficiency, and in reducing burden of chronic diseases. This study is aimed at defining the …

Multifactorial Fall Interventions For People Over 65 Years In The Acute Hospital Setting: Pre–Post-Test Design, Allison Wallis, Christina Aggar, Deb Massey

Research outputs 2022 to 2026

Background: Falls are the most reported patient safety incident for patients >65 years in acute hospital settings worldwide. While multifactorial fall interventions reduce the number of falls in subacute and rehabilitation settings, fall interventions in acute hospital settings are unknown. Aim: To evaluate the effectiveness of multifactorial fall interventions on the number of falls using codesigned education targeting staff and the patient and review the environment in acute hospital settings in NSW, Australia for patients over 65 years of age. Method: A pre–post-test design with a non-equivalent group was conducted. All acute hospital inpatient falls occurring both pre- and post-intervention …