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Articles 93091 - 93120 of 941121
Full-Text Articles in Entire DC Network
Data Sovereignty And Trade Agreements: Three Digital Kingdoms, Henry S. Gao
Data Sovereignty And Trade Agreements: Three Digital Kingdoms, Henry S. Gao
Research Collection Yong Pung How School Of Law
For centuries, international lawyers have wrestled with the relationship between national sovereignty and international law. This is also the case of international trade law, where the tension between trade liberalization and national sovereignty culminated in the famous “Great 1994 Sovereignty Debate” between the late Prof. John Jackson and other leading scholars when the WTO came into being. As we enter the digital age, the issue of sovereignty resurfaced once again in the form of data sovereignty. In this paper, I will examine provisions in trade agreements which deal with data sovereignty issues, such as restrictions on data flow such as …
Regulating Online Hate Speech: The Singapore Experiment, Siyuan Chen
Regulating Online Hate Speech: The Singapore Experiment, Siyuan Chen
Research Collection Yong Pung How School Of Law
In Singapore, the introduction of the Protection from Online Falsehoods and Manipulation Act 2019 (POFMA) generated considerable debate and feedback. One of the main concerns was whether the law would unduly restrict the freedom of expression. In focusing on the provisions of POFMA that could possibly apply to hate speech, this paper situates the criticisms within the larger framework of international human rights law and international practices and proposes some ways forward to improve the regulatory framework for online hate speech.
In Vitro Assessment Of Protamine Toxicity With Neural Cells, Its Therapeutic Potential To Counter Chondroitin Sulfate Mediated Neuron Inhibition, And Its Effects On Reactive Astrocytes, Derek W. Nelson, Jessica L. Funnell, Conrad H. Cheung, Geraldine B. Quinones, Christina S. Mendoza, Marvin Bentley, Ryan J. Gilbert
In Vitro Assessment Of Protamine Toxicity With Neural Cells, Its Therapeutic Potential To Counter Chondroitin Sulfate Mediated Neuron Inhibition, And Its Effects On Reactive Astrocytes, Derek W. Nelson, Jessica L. Funnell, Conrad H. Cheung, Geraldine B. Quinones, Christina S. Mendoza, Marvin Bentley, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
Multiple therapies have been studied to ameliorate the neuroinhibitory cues present after traumatic injury to the central nervous system. Two previous in vitro studies have demonstrated the efficacy of the Food and Drug Administration-approved cardiovascular therapeutic, protamine (PRM), to overcome neuroinhibitory cues presented by chondroitin sulfates; however, the effect of a wide range of PRM concentrations on neuronal and glial cells has not been evaluated. In this study, we investigate the therapeutic efficacy of PRM with primary cortical neurons, hippocampal neurons, mixed glial cultures, and astrocytes. The threshold for PRM toxicity is shown to be at or above 10 µg …
Positioning Podcasting As Legal Scholarship, Sara Gras
Positioning Podcasting As Legal Scholarship, Sara Gras
Utah Law Review
Technology has revolutionized legal practice, education, and societygenerally, yet the availability of new forms of digital media has notsignificantly changed the locus of legal scholarship. This Article examineswhether our collective understanding of where scholarship can existshould expand to include podcasting as a formally acknowledged mediumfor legal scholarship. Student-edited law journals remain the primaryvehicle for disseminating law faculty scholarship, as well as an importantmeasure of faculty productivity and success as scholars, even though mostlegal research is conducted online. Despite acknowledged structurallimitations and biases inherent in the academic law review system,traditional print law journals continue to be more highly placed on thehierarchy …
Democratic Erosion And The United States Supreme Court, Jenny Breen
Democratic Erosion And The United States Supreme Court, Jenny Breen
Utah Law Review
For many decades, confidence in American institutions and political culture consistently led scholars to sideline questions about “regime change” in the United States. And for many years, that approach seemed justified. Democratic institutions were firmly rooted and stable, and American voters participated in free and fair elections that resulted in the peaceful transfer of power between parties and candidates. Then came the campaign of Donald Trump and all that has followed since, including open challenges to the most basic and fundamental democratic norms. These changes have led many voters, commentators, and scholars to ask: Is democracy eroding in the United …
Introduction: Special Issue: The Pandemic Of Covid-19 In Latin America And The Caribbean Higher Education: An Invitation To Remember And Reflect Into The Future
Journal of Comparative & International Higher Education
No abstract provided.
The Graduating International Undergraduate Class Of 2020—Counterintuitive Graduation Rate And Time To Degree During Onset Of The Coronavirus Pandemic
Journal of Comparative & International Higher Education
No abstract provided.
Dataset Of Arabic Spam And Ham Tweets, Sanaa Kaddoura, Safaa Henno
Dataset Of Arabic Spam And Ham Tweets, Sanaa Kaddoura, Safaa Henno
All Works
This data article provides a dataset of 132421 posts and their corresponding information collected from Twitter social media. The data has two classes, ham or spam, where ham indicates non-spam clean tweets. The main target of this dataset is to study a way to classify whether a post is a spam or not automatically. The data is in Arabic language only, which makes the data essential to the researchers in Arabic natural language processing (NLP) due to the lack of resources in this language. The data is made publicly available to allow researchers to use it as a benchmark for …
Developing A Success Model Of A Social Student Relationship Management System, Wasef Mater, Monther Aldwairi, Nasim Matar, Waleed Al-Rahmi
Developing A Success Model Of A Social Student Relationship Management System, Wasef Mater, Monther Aldwairi, Nasim Matar, Waleed Al-Rahmi
All Works
Social media's significance in higher education has increased due to its capacity to enhance participation, communication, teamwork, and information sharing. Important notifications, updates, and reminders can be promptly received by all members of the university community, assuring that information is shared with everyone. The objective of this study is to develop a model for a Customer Relationship Management (CRM) system in higher education that is based on social media and intends to increase student satisfaction, loyalty, and profitability. It blends the idea of trust with Delone Mclean success model. Partial Least Squares-Structural Equation Modeling (PLS-SEM) was used to evaluate the …
Professionalizing A Student’S Library Employment Through Experiential Learning Workshops, Marissa Anne Bischoff, Matt Armstrong, David Waddell
Professionalizing A Student’S Library Employment Through Experiential Learning Workshops, Marissa Anne Bischoff, Matt Armstrong, David Waddell
Faculty Publications
If intentional, college students in campus jobs can develop professional skills valued in the post-college workforce. However, many students are not likely to realize the potential of their experience without advisement or instruction that teaches them how to reflect on experience and articulate its value, usually in the form of a resume or in an interview. This study examines the value of three workshops to help students reflect on their development of NACE career readiness competencies as a result of their library work experience. Survey and focus group data suggest students’ confidence in their ability to articulate and apply their …
Men Are From Mars And Women Are From Venus: Dyadic Collaboration In The Metaverse, Shu Schiller, Fiona Fui-Hoon Nah, Andy Luse, Keng Siau
Men Are From Mars And Women Are From Venus: Dyadic Collaboration In The Metaverse, Shu Schiller, Fiona Fui-Hoon Nah, Andy Luse, Keng Siau
Research Collection School Of Computing and Information Systems
Purpose: The gender composition of teams remains an important yet complex element in unlocking the success of collaboration and performance in the metaverse. In this study, the authors examined the collaborations of same- and mixed-gender dyads to investigate how gender composition influences perceptions of the dyadic collaboration process and outcomes at both the individual and team levels in the metaverse. Design/methodology/approach: Drawing on expectation states theory and social role theory, the authors hypothesized differences between dyads of different gender compositions. A blocked design was utilized where 432 subjects were randomly assigned to teams of different gender compositions: 101 male dyads, …
Lebanon Needs Food, Water, Medicine And Social Media, Elisabeth Croese
Lebanon Needs Food, Water, Medicine And Social Media, Elisabeth Croese
Theses and Dissertations
Lebanon has a history of instability, weak governance, and a strong civil society. The country has been in a state of crisis for decades and currently, the state is experiencing multiple crises at once. Political tensions, an economic crisis, and plummeting of the Lebanese Lira, together with the COVID-19 crisis have amounted to the instability of the state. All these tensions escalated even further when Beirut experienced a huge explosion in the port on 4 August 2020, killing over two hundred people and injuring thousands.
Civil society organizations play a crucial role in the development and survival of Lebanon. In …
Rethinking Female Genital Cutting Through Postcolonial Lens, Erika Carvalho
Rethinking Female Genital Cutting Through Postcolonial Lens, Erika Carvalho
Theses and Dissertations
Due to global instabilities, the resulting international displacement and rising inter- cultural tensions within Western societies have relocated gendered cultural practices at the center of contemporary debates on multiculturalism, social cohesion and migration. In this context, female genital cutting (FGC) has re-emerged as a symbol of savagery, portrayed as a symbol of “otherness”, a true global violation of women’s rights. While the increasing attention given to these practices is a testament to reinvigorated feminist activism, FGC has also been harnessed for the purposes of reproducing colonial discourses about the “Third World”, which have been integral to the revival of many …
Influencers Of Resident Attitudes Towards Tourism: The Shortfall In Our Assessment Methods, Christopher S. Dutt
Influencers Of Resident Attitudes Towards Tourism: The Shortfall In Our Assessment Methods, Christopher S. Dutt
Journal of Global Hospitality and Tourism
The study of residents’ perceptions and attitudes towards tourism has received considerable interest over the years. While much agreement has been found, there are also several areas of disagreement and noteworthy gaps that affect our understanding of residents’ attitudes toward tourism. This discussion reviews some of the existing findings of past studies, before considering some of the significant gaps. These include the dominance of social exchange theory (SET) as the principal model, the lack of distinction between tourists and tourism, and the impact of tourist typologies on perceptions of tourism.
Tourist Engagement Model Of Regenerative Tourism Destinations: A Case Study Of Egon Buluk Tourism Village, Sikka Regency, East Nusa Tenggara Province, Michael Rudolfus Sawu, Muhammad Ridla
Tourist Engagement Model Of Regenerative Tourism Destinations: A Case Study Of Egon Buluk Tourism Village, Sikka Regency, East Nusa Tenggara Province, Michael Rudolfus Sawu, Muhammad Ridla
Journal of Global Hospitality and Tourism
The research aims to analyze regenerative tourism components products, tourists’ perceptions, tourists’ experiences, and regenerative tourism development policies while involving tourists as co-creators. The research utilizes a qualitative method with a phenomenological approach. In-depth interviews were conducted with 27 stakeholders related to the tourist engagement model in the development of tourism destinations at the village scale. This research found that the development of regenerative tourism product components showcases uniqueness and beauty on a massive scale due to being situated in conservation areas. However, there is a need for improvement in other components to provide a sense of safety, comfort, and …
Generative Artificial Intelligence (Gai) In Hospitality And Tourism Marketing: Perceptions, Risks, Benefits, And Policy Implications, Usman Khan, Kashif Ali Khan
Generative Artificial Intelligence (Gai) In Hospitality And Tourism Marketing: Perceptions, Risks, Benefits, And Policy Implications, Usman Khan, Kashif Ali Khan
Journal of Global Hospitality and Tourism
This study investigates the integration of generative artificial intelligence (GAI) into hospitality and tourism marketing and its implications for industry professionals in the United States. This study employed a mixed methods approach, gathering qualitative insights from 20 professionals and quantitative data from a sample of 163 participants. The qualitative study revealed concerns about data privacy, customer trust, and ethical considerations regarding GAI implementation. However, participants acknowledged its potential to enhance personalization, engagement, and operational efficiency. The quantitative study supported these findings by showing a level of concern about risks but agreement on the benefits of GAI. Additionally, the participants were …
A Finite Element Model For Hydro-Thermal Convective Flow In A Porous Medium: Effects Of Hydraulic Resistivity And Thermal Diffusivity, S. M. Mallikarjunaiah, Dambaru Bhatta
A Finite Element Model For Hydro-Thermal Convective Flow In A Porous Medium: Effects Of Hydraulic Resistivity And Thermal Diffusivity, S. M. Mallikarjunaiah, Dambaru Bhatta
School of Mathematical & Statistical Sciences Faculty Publications
In this article, a finite element model is implemented to analyze hydro-thermal convective flow in a porous medium. The mathematical model encompasses Darcy’s law for incompressible fluid behavior, which is coupled with a convection-diffusion-type energy equation to characterize the temperature in the porous medium. The current investigation presents an efficient, stable, and accurate finite element discretization for the hydro-thermal convective flow model. The well-posedness of the proposed discrete Galerkin finite element formulation is guaranteed due to the decoupling property and the linearity of the numerical method. Computational experiments confirm the optimal convergence rates for a manufactured solution. Several numerical results …
Uab Department Of Music Presents Performances For Spring 2024, Shannon Thomason
Uab Department Of Music Presents Performances For Spring 2024, Shannon Thomason
Browse All News
No abstract provided.
Metabolism, Fibrosis, And Apoptosis: The Effect Of Lipids And Their Derivatives On Keloid Formation, Chen-Yu Li, Ru-Xin Xie, Shi-Wei Zhang, Jiao Yun, Ai Zhong, Ying Cen, Jun-Jie Chen
Metabolism, Fibrosis, And Apoptosis: The Effect Of Lipids And Their Derivatives On Keloid Formation, Chen-Yu Li, Ru-Xin Xie, Shi-Wei Zhang, Jiao Yun, Ai Zhong, Ying Cen, Jun-Jie Chen
Faculty, Staff and Student Publications
Keloids, pathological scars resulting from skin trauma, have traditionally posed significant clinical management challenges due to their persistence and high recurrence rates. Our research elucidates the pivotal roles of lipids and their derivatives in keloid development, driven by underlying mechanisms of abnormal cell proliferation, apoptosis, and extracellular matrix deposition. Key findings suggest that abnormalities in arachidonic acid (AA) synthesis and non-essential fatty acid synthesis are integral to keloid formation. Further, a complex interplay exists between lipid derivatives, notably butyric acid (BA), prostaglandin E2 (PGE2), prostaglandin D2 (PGD2), and the regulation of hyperfibrosis. Additionally, combinations of docosahexaenoic acid (DHA) with BA …
Anatomy Of The Female Reproductive Tract Organs Of The Brown Anole (Anolis Sagrei), Bonnie K Kircher, Edward L Stanley, Richard R Behringer
Anatomy Of The Female Reproductive Tract Organs Of The Brown Anole (Anolis Sagrei), Bonnie K Kircher, Edward L Stanley, Richard R Behringer
Faculty, Staff and Student Publications
Female reproduction in squamate reptiles (lizards and snakes) is highly diverse and mode of reproduction, clutch size, and reproductive tract morphology all vary widely across this group of ~11,000 species. Recently, CRISPR genome editing techniques that require manipulation of the female reproductive anatomy have been developed in this group, making a more complete understanding of this anatomy essential. We describe the adult female reproductive anatomy of the model reptile the brown anole (Anolis sagrei). We show that the brown anole female reproductive tract has three distinct anterior-to-posterior regions, the infundibulum, the glandular uterus, and the nonglandular uterus. The infundibulum has …
Vietnam War Through The Lens, Caitlyn Mccranie, Abby Noonan, Sutton Patterson
Vietnam War Through The Lens, Caitlyn Mccranie, Abby Noonan, Sutton Patterson
Armstrong Undergraduate Journal of History
No abstract provided.
Sparse Bayesian Variable Selection In High‐Dimensional Logistic Regression Models With Correlated Priors, Zhuanzhuan Ma, Zifei Han, Souparno Ghosh, Liucang Wu, Min Wang
Sparse Bayesian Variable Selection In High‐Dimensional Logistic Regression Models With Correlated Priors, Zhuanzhuan Ma, Zifei Han, Souparno Ghosh, Liucang Wu, Min Wang
School of Mathematical & Statistical Sciences Faculty Publications
In this paper, we propose a sparse Bayesian procedure with global and local(GL) shrinkage priors for the problems of variable selection and classification in high-dimensional logistic regression models. In particular, we consider two types of GL shrinkage priors for the regression coefficients, the horseshoe (HS)prior and the normal-gamma (NG) prior, and then specify a correlated prior for the binary vector to distinguish models with the same size. The GL priors are then combined with mixture representations of logistic distribution to construct a hierarchical Bayes model that allows efficient implementation of a Markov chain Monte Carlo (MCMC) to generate samples from …
The Buzz Within: The Role Of The Gut Microbiome In Honeybee Social Behavior, J. B. Nguyen, Christopher Marshall, Chelsea N. Cook
The Buzz Within: The Role Of The Gut Microbiome In Honeybee Social Behavior, J. B. Nguyen, Christopher Marshall, Chelsea N. Cook
Biological Sciences Faculty Research and Publications
Gut symbionts influence the physiology and behavior of their host, but the extent to which these effects scale to social behaviors is an emerging area of research. The use of the western honeybee (Apis mellifera) as a model enables researchers to investigate the gut microbiome and behavior at several levels of social organization. Insight into gut microbial effects at the societal level is critical for our understanding of how involved microbial symbionts are in host biology. In this Commentary, we discuss recent findings in honeybee gut microbiome research and synthesize these with knowledge of the physiology and behavior …
Us Public Opinion About The Safety Of Gene Editing In The Agriculture And Medical Fields And The Amount Of Evidence Needed To Improve Opinions, Brandon R. Mcfadden, Joy N. Rumble, Kathryn A. Stofer, Kevin M. Folta
Us Public Opinion About The Safety Of Gene Editing In The Agriculture And Medical Fields And The Amount Of Evidence Needed To Improve Opinions, Brandon R. Mcfadden, Joy N. Rumble, Kathryn A. Stofer, Kevin M. Folta
Agricultural Economics and Agribusiness Faculty Publications and Presentations
Introduction: Implementation of gene editing in agriculture and medicine hinges on public acceptance. The objectives of this study were to explore U.S. public opinion about gene editing in agricultural and medical fields and to provide more insight into the relationship between opinions about the safety of gene editing and the potential impact of evidence to improve opinions about safety.
Methods: Data were from two samples of U.S. respondents: 1,442 respondents in 2021 and 3,125 respondents in 2022. Survey respondents provided their opinions about the safety of gene editing in the agricultural and medical fields and answered questions about the number …
Broadening Participation Of Teachers In Computing: Examining Postsecondary Educational Experiences And Prospective Educators’ Cs Teaching Interests, Robert Schwarzhaupt, Alexsandra Galanis, Joanna Goode, Kate Blanchard, Jill Bowdon, Joseph P. Wilson
Broadening Participation Of Teachers In Computing: Examining Postsecondary Educational Experiences And Prospective Educators’ Cs Teaching Interests, Robert Schwarzhaupt, Alexsandra Galanis, Joanna Goode, Kate Blanchard, Jill Bowdon, Joseph P. Wilson
Journal of Computer Science Integration
Teacher shortages in K–12 computer science (CS) education negatively impact students’ access to CS courses, exposure to CS concepts, and interest in CS-related careers. To address CS teacher shortages, this study seeks to understand factors related to expressing a preference to teach CS among prospective teachers. The study team analyzed data from 27,700 prospective teacher applications accepted into the 2016–2020 Teach For America (TFA) corps (cohorts). The TFA corps is an alternative teacher development program that recruits and prepares participants to obtain their teaching certification while they work for at least two years in underserved communities on a temporary teaching …
Pluripotency Of A Founding Field: Rebranding Developmental Biology, Crystal D Rogers, Chris Amemiya, Swathi Arur, Leslie Babonis, Michael Barresi, Madelaine Bartlett, Richard Behringer, Blair Benham-Pyle, Dominique Bergmann, Ben Blackman, C Titus Brown, Bill Browne, Jasmin Camacho, Chiswili Yves Chabu, Ida Chow, Ondine Cleaver, Jonah Cool, Megan Y Dennis, Alexandra Jazz Dickinson, Stefano Di Talia, Margaret Frank, Stewart Gillmor, Eric S Haag, Iswar Hariharan, Richard Harland, Aman Husbands, Loydie Jerome-Majewska, Kristen Koenig, Carole Labonne, Michael Layden, Chris Lowe, Madhav Mani, Megan Martik, Katelyn Mckown, Cecilia Moens, Christian Mosimann, Joyce Onyenedum, Robert Reed, Ajna Rivera, Dan Rokhsar, Loic Royer, Flora Rutaganira, Rachel Shahan, Neelima Sinha, Billie Swalla, Jaimie M Van Norman, Daniel E Wagner, Athula Wikramanayake, Sophia Zebell, Siobhán M Brady
Pluripotency Of A Founding Field: Rebranding Developmental Biology, Crystal D Rogers, Chris Amemiya, Swathi Arur, Leslie Babonis, Michael Barresi, Madelaine Bartlett, Richard Behringer, Blair Benham-Pyle, Dominique Bergmann, Ben Blackman, C Titus Brown, Bill Browne, Jasmin Camacho, Chiswili Yves Chabu, Ida Chow, Ondine Cleaver, Jonah Cool, Megan Y Dennis, Alexandra Jazz Dickinson, Stefano Di Talia, Margaret Frank, Stewart Gillmor, Eric S Haag, Iswar Hariharan, Richard Harland, Aman Husbands, Loydie Jerome-Majewska, Kristen Koenig, Carole Labonne, Michael Layden, Chris Lowe, Madhav Mani, Megan Martik, Katelyn Mckown, Cecilia Moens, Christian Mosimann, Joyce Onyenedum, Robert Reed, Ajna Rivera, Dan Rokhsar, Loic Royer, Flora Rutaganira, Rachel Shahan, Neelima Sinha, Billie Swalla, Jaimie M Van Norman, Daniel E Wagner, Athula Wikramanayake, Sophia Zebell, Siobhán M Brady
Faculty, Staff and Student Publications
The field of developmental biology has declined in prominence in recent decades, with off-shoots from the field becoming more fashionable and highly funded. This has created inequity in discovery and opportunity, partly due to the perception that the field is antiquated or not cutting edge. A 'think tank' of scientists from multiple developmental biology-related disciplines came together to define specific challenges in the field that may have inhibited innovation, and to provide tangible solutions to some of the issues facing developmental biology. The community suggestions include a call to the community to help 'rebrand' the field, alongside proposals for additional …
Novel Hemizygous Single-Nucleotide Duplication In Rpgr In A Patient With Retinal Dystrophy And Sensorineural Hearing Loss, Ryan J German, Blake Vuocolo, Liesbeth Vossaert, Nichole Owen, Richard A Lewis, Lisa Saba, Texome Project, Michael F Wangler, Sandesh Nagamani
Novel Hemizygous Single-Nucleotide Duplication In Rpgr In A Patient With Retinal Dystrophy And Sensorineural Hearing Loss, Ryan J German, Blake Vuocolo, Liesbeth Vossaert, Nichole Owen, Richard A Lewis, Lisa Saba, Texome Project, Michael F Wangler, Sandesh Nagamani
Duncan NRI Faculty and Staff Publications
Background: The RPGR gene has been associated with X-linked cone-rod dystrophy. This report describes a variant in RPGR detected with exome sequencing (ES). Genes like RPGR have not always been included in panel-based testing and thus genome-wide tests such as ES may be required for accurate diagnosis.
Methods: The Texome Project is studying the impact of ES in medically underserved patients who are in need of genomic testing to guide diagnosis and medical management. The hypothesis is that ES could uncover diagnoses not made by standard medical care.
Results: A 58-year-old male presented with retinitis pigmentosa, sensorineural hearing loss, and …
Matr3 Pathogenic Variants Differentially Impair Its Cryptic Splicing Repression Function, Mashiat Khan, Xiao Xiao Lily Chen, Michelle Dias, Jhune Rizsan Santos, Sukhleen Kour, Justin You, Rebekah Van Bruggen, Mohieldin M M Youssef, Ying-Wooi Wan, Zhandong Liu, Jill A Rosenfeld, Qiumin Tan, Udai Bhan Pandey, Hari Krishna Yalamanchili, Jeehye Park
Matr3 Pathogenic Variants Differentially Impair Its Cryptic Splicing Repression Function, Mashiat Khan, Xiao Xiao Lily Chen, Michelle Dias, Jhune Rizsan Santos, Sukhleen Kour, Justin You, Rebekah Van Bruggen, Mohieldin M M Youssef, Ying-Wooi Wan, Zhandong Liu, Jill A Rosenfeld, Qiumin Tan, Udai Bhan Pandey, Hari Krishna Yalamanchili, Jeehye Park
Duncan NRI Faculty and Staff Publications
Matrin-3 (MATR3) is an RNA-binding protein implicated in neurodegenerative and neurodevelopmental diseases. However, little is known regarding the role of MATR3 in cryptic splicing within the context of functional genes and how disease-associated variants impact this function. We show that loss of MATR3 leads to cryptic exon inclusion in many transcripts. We reveal that ALS-linked S85C pathogenic variant reduces MATR3 solubility but does not impair RNA binding. In parallel, we report a novel neurodevelopmental disease-associated M548T variant, located in the RRM2 domain, which reduces protein solubility and impairs RNA binding and cryptic splicing repression functions of MATR3. Altogether, our research …
Covid-19 Vaccine Perspective From Adolescents' Lens In The Us, Meher Garg, Arnav A. Nagrecha, Ruchi Gupta, Makeba Williams
Covid-19 Vaccine Perspective From Adolescents' Lens In The Us, Meher Garg, Arnav A. Nagrecha, Ruchi Gupta, Makeba Williams
2020-Current year OA Pubs
Introduction The COVID-19 pandemic has presented an unprecedented global health issue. The World Health Organization estimates 773 million confirmed cases and 7 million deaths. Vaccination continues to be the most effective way to prevent COVID-19 and has demonstrated safety and efficacy in all age groups. Though a lot of studies have looked at COVID-19 vaccination acceptance and hesitancy in adults, there is scarce research addressing adolescent vaccination readiness. COVID-19 infection in this age group may result in lost school days, school and community transmission, and loss of productivity for parents. Aim This study aims to determine COVID-19 vaccination rates and …
High-Dimensional Quantile Mediation Analysis With Application To A Birth Cohort Study Of Mother-Newborn Pairs, Haixiang Zhang, Xiumei Hong, Yinan Zheng, Lifang Hou, Cheng Zheng, Xiaobin Wang, Lei Liu
High-Dimensional Quantile Mediation Analysis With Application To A Birth Cohort Study Of Mother-Newborn Pairs, Haixiang Zhang, Xiumei Hong, Yinan Zheng, Lifang Hou, Cheng Zheng, Xiaobin Wang, Lei Liu
2020-Current year OA Pubs
MOTIVATION: There has been substantial recent interest in developing methodology for high-dimensional mediation analysis. Yet, the majority of mediation statistical methods lean heavily on mean regression, which limits their ability to fully capture the complex mediating effects across the outcome distribution. To bridge this gap, we propose a novel approach for selecting and testing mediators throughout the full range of the outcome distribution spectrum.
RESULTS: The proposed high-dimensional quantile mediation model provides a comprehensive insight into how potential mediators impact outcomes via their mediation pathways. This method's efficacy is demonstrated through extensive simulations. The study presents a real-world data application …