Digital Commons Network^™

Injectable Ionic Hydrogel Conductors: Advancing Material Design To Transform Cardiac Pacing, Gabriel J Rodriguez-Rivera, Allison Post, Mathews John, Derek Bashe, Fei Xu, Trace Larue, Abbey Nkansah, Megan Wancura, Malgorzata Chwatko, Christina Waldron, Nikhith Kalkunte, Janet Zoldan, Mathieu Arseneault, Abdou Elgalad, Manuel K Rausch, Mehdi Razavi, Elizabeth Cosgriff-Hernandez

Faculty, Staff and Students Publications

Direct pacing of the mid myocardium where re-entry originates can be used to prevent ventricular arrhythmias and circumvent the need for painful defibrillation or cardiac ablation. However, there are no pacing electrodes small enough to navigate the coronary veins that cross these culprit scar regions. To address this need, we have developed an injectable ionically conductive hydrogel electrode that can fill the epicardial coronary veins and transform them into flexible electrodes. A new hydrogel chemistry based on a polyether urethane diacrylamide macromer was developed that matches myocardial stiffness and is resistant to hydrolysis. Conductivity was imparted using ionic precursor solutions …

A Sumo-Interacting Motif In The Guanine Nucleotide Exchange Factor Epac1 Is Required For Subcellular Targeting And Function, Wenli Yang, Fang Mei, Wei Lin, Jason E Lee, Si Nie, Christopher J Bley, André Hoelz, Xiaodong Cheng

The Brown Foundation: Institute of Molecular Medicine

Exchange protein directly activated by cAMP (EPAC1), a multifunctional intracellular cAMP receptor, dynamically localizes to various cellular loci, engaging with diverse molecular partners to maintain cellular homeostasis. The study investigates the role of the SUMO-interacting motif (SIM) in the subcellular targeting and cellular functions of EPAC1. It reveals that the SIM is a critical structural element for EPAC1's association with RanBP2/nucleoporin 358, a nucleoporin of the cytoplasmic filament component of the nuclear pore complex. Mutational disruption of EPAC1 SIM interferes with EPAC1's ability to activate its canonical effectors, small GTPases, Rap1 and Rap2, and noncanonical functions, such as the formation …

Visual Literacy Instruction At Scale: Developing Asynchronous Learning Objects For First-Year Art And Design Students, Jacqueline Huddle, Sarah Carter

Communications in Information Literacy

While learning modules are not new to academic librarianship, student-centered, asynchronous learning modules are an innovative approach not commonly considered within the academic librarianship literature. This article discusses the development and implementation of visual literacy asynchronous learning modules created by two librarians for a cohort of first-year studio art students. In creating these modules, the goal was to offer studio art students visual literacy instruction specific to their personal interests and future careers. Specifically, this article discusses the module design process and how student-centered learning can be incorporated into modules in order to offer deep learning opportunities.

Exploring Positional Knowledge: Using Theory To Teach Bias, Thomas C. Weeks, Melissa E. Johnson

Communications in Information Literacy

In this article, the authors explain how librarians can use positionality theory to understand how students produce value judgments around questions of bias, authority, and credibility. Librarians can help guide students to recognize the student’s own positionality when approaching issues of bias. Students are often instructed to choose credible sources for their research, which they often interpret as sources that avoid bias. Source evaluation tools and checklists, such as the CRAAP test and SIFT, also tell students to watch out for biased language. Unfortunately, many people, students and librarians alike, misunderstand bias and fail to recognize its significance in the …

Enditnow Impact Study Findings, Shannon M. Trecartin, René Drumm, Petr Cincala, Ellen Nogueira Rodrigues, Yazmik Cantillano, Kayla-Hope Bruno, Lalramliani Ralte

Faculty Publications

In January 2025, researchers at Andrews University (AU) initiated a study to evaluate Seventh-day Adventist churches’ engagement with the 2024 Abuse Prevention or enditnow Sabbath. The purpose of the study was initially to assess visibility and participation through the publicly available digital platforms of the sampled churches. The findings from that investigation were reported to the Departments of Archives and Statistics and Women’s Ministries in June 2025. The study’s scope expanded when researchers received a faculty research grant from Andrews University’s Office of Research to further investigate how Adventist churches across the NAD participate in the enditnow Sabbath. This report …

Raising The Roof For All: Integrating Companion Planting Ecology, Policy And Community In Portland's Green Roof Future, Zoe Edelman

University Honors Theses

Green roofs, or ecoroofs, provide environmental and social benefits in urban areas. Ecoroofs manage stormwater by absorbing rainfall, reducing rooftop temperatures, supporting pollinators, and offering green space in densely developed cities. Portland, Oregon has adopted progressive policies that encourage green roof installation through incentives and building requirements. However, many ecoroofs in the city are underperforming due to poor maintenance, low public awareness, and limited access to rooftop spaces. This thesis explores whether companion planting can improve the ecological performance and long- term viability of extensive green roofs. A rooftop experiment at Portland State University tested the growth of radishes, with …

More Than Hormones: Psychological Consequences Of The Medicalized Menopausal Experience, Haley Derrickson

University Honors Theses

Menopause, a transitional period that roughly half the population may experience, has a high degree of variability in onset and intensity of symptoms, one of which is depression. It is also a period in which the lives of those transitioning are highly medicalized. This literature review investigates how medicalization has increased since the term was created, and how it impacts perimenopause, menopause, and mental health.

American Consumer Culture And Social Media Polarization: Analyzing Twentieth Century Trends And Their Effects On Twenty First Century Politics, Max Lally

University Honors Theses

The emergence of social media as a mainstream communication technology during the early twenty first century has had an outsized impact on the United States' political system. By analyzing trends in American culture and economics beginning in the decades following the end of World War Two, the circumstances that shaped social media during its development can be tied to long term historical changes. Shifts away from traditional models of community and towards rising individualism reshaped communication with both political allies and opponents. Generational shifts in political attitudes have heightened these divisions as well, as younger and liberal perspectives challenge traditional, …

Cultural Shadows: Vampires And The Shifting Fears Of The West, A Creative Exploration Of Vampire Media And Its Reflection Of Evolving Social Anxieties, Tasha Sayre

University Honors Theses

Cultural Shadows: Vampires and the Shifting Fears of the West is a creative-critical thesis that explores vampire media as a reflection of evolving social anxieties in Western culture. Focusing primarily on film and television, with reference to key literary texts, this study examines how the vampire figure is used to articulate and dramatize recurring societal fears—particularly those surrounding women's sexuality and autonomy, queer identity, and class-based inequality. Through close readings of influential vampire narratives, the thesis demonstrates how these stories mirror cultural tensions and moral panics, transforming the vampire into a symbol of both fear and fascination. Drawing on gender …

Early-Stage Detection Of Copper Ion Release From Bronze Corrosion Using Uv/Vis Spectroscopy And Hydrogel Sensing, Hibah Khan

University Honors Theses

Detecting copper(I) (Cu⁺) release at early corrosion stages is important for preserving bronze heritage materials. This study investigated the use of neocuproine (NC), a Cu⁺-specific ligand, for simple and selective colorimetric detection of Cu⁺ in solution. NC reacts with Cu⁺ to form a Cu(NC)₂ complex, which produces a distinct orange-red color with peak absorbance at 455 nm. Solutions were prepared with varying concentrations of Cu⁺ generated by reducing Cu²⁺ with excess ascorbic acid. Ultraviolet/Visible (UV/Vis) spectroscopy was used to quantify absorbance changes. The absorbance at 455 nm increased linearly across the tested Cu⁺ concentration range (6.25–200 µM) with an R² …

The Competitive Advantage Of Storytelling, Jennifer V. Carroll

University Honors Theses

Ava Roasteria Company, a family-owned coffee business in Washington County, Oregon, faces the challenge of expanding in a saturated market. Despite a compelling origin story rooted in environmental remediation and community revitalization, Ava has not utilized this narrative in its branding. This capstone project applied strategic business and marketing frameworks to identify narrative storytelling as a key competitive advantage. Research shows that authentic, narrative origin stories of small businesses that align with stakeholder's values and beliefs can foster emotional connection, loyalty, and brand differentiation. Ava's history and alignment with the Portland culture of sustainability and social responsibility is an untapped …

Assessing The Challenges Latin Immigrant Populations Face In Accessing Healthcare And Proposing Solutions To Improve Accessibility, Melina Khiabani

University Honors Theses

Access to healthcare is considered a basic human right, yet many Hispanic and Latin immigrant populations in the United States, especially those living in rural areas, face significant barriers that prevent them from receiving the care they need. These barriers include language differences, cultural misunderstandings, financial hardship, fear of legal consequences, and geographic isolation. This literature review explores the challenges that Hispanic/Latin immigrants aged 19-25 in rural areas encounter when trying to access healthcare, particularly preventative services.

Drawing from a wide range of existing research, this thesis identifies how policy restrictions, social determinants of health, and systemic discrimination contribute to …

Nf2 Loss-Of-Function And Hypoxia Drive Radiation Resistance In Grade 2 Meningiomas, Bhuvic Patel, Sangami Pugazenthi, Shree S Pari, Tatenda Mahlokozera, William A Leidig, Hsiang-Chih Lu, Alicia Yang, Kaleigh Roberts, Patrick Desouza, Kyle P Mcgeehan, Diane D Mao, Namita Sinha, Joseph E Ippolito, Sonika Dahiya, Hiroko Yano, Albert H Kim, Et Al.

2020-Current year OA Pubs

BACKGROUND: World Health Organization Grade 2 meningiomas (G2Ms) often recur and resist therapies. Grade 2 meningiomas with histopathological necrosis have been associated with worse local control (LC) after radiation therapy, but the drivers and biomarkers of radiation resistance in G2Ms remain unknown.

METHODS: We performed genetic sequencing and histopathological analysis of 113 G2Ms and investigated the role of genetic and microenvironmental factors on clonogenic survival after ionizing radiation. We performed transcriptional profiling of our in vitro model and 18 human G2M tumors by bulk RNA sequencing as well as 8 G2Ms by single nuclei RNA sequencing.

RESULTS: NF2 loss-of-function (LOF) …

Telemedicine In Nerve Surgery: An Effective Method To Determine Indications For Surgery, Noah S. Llaneras, Ruby L. Taylor, Jonah P. M. Orr, Rachel Alessio, Carolyn Carper, Brendan M. Patterson, Susan E. Mackinnon

2020-Current year OA Pubs

BACKGROUND: The COVID-19 pandemic accelerated the adoption of telemedicine for surgical consultations. Although patient satisfaction has been well documented, limited research exists regarding telemedicine's effectiveness in determining the ability to indicate for surgical care compared with in-office visits. We conducted a retrospective review comparing surgical decision-making via telemedicine versus in-person consultations, hypothesizing that in-office visits would be more effective in establishing a surgical plan than telemedicine.

METHODS: A retrospective review of the medical records of all new patients presenting to the senior author's nerve surgery clinic at a high-volume quaternary referral center between June 2020 and January 2023 was performed. …

Correlation Of Ultrasound And Electrodiagnostic Evaluation In Ballistic Peripheral Nerve Injuries, Mitchell S. Mologne, Zachary D. Randall, Nathan P. Olafsen, David M. Brogan, Christopher J. Dy

2020-Current year OA Pubs

BACKGROUND: Evaluation and management of ballistic peripheral nerve injuries remain controversial, and recent series have suggested higher rates of nerve discontinuity than previously appreciated. Ultrasound (US) may aid clinicians in the management of ballistic injuries. The goal of this study was to compare US findings to electrodiagnostic and intraoperative findings to assess its accuracy in ballistic injuries.

METHODS: We conducted a retrospective review of patients with the following criteria: (1) ballistic injury to the upper or lower extremity with suspected mixed or motor peripheral nerve injury; (2) underwent electrodiagnostic studies (EDX) and peripheral nerve ultrasound. US findings were categorized as …

Genetically Encoded Biosensors Of Metabolic Function For The Study Of Neurodegeneration, A Review And Perspective, Minglei Zhao, Saman Behboudi Tanourlouee, Sean Mccracken, Philip R Williams

2020-Current year OA Pubs

Nervous system tissue is the most metabolically active in the body and neurons are the primary consumers of oxygen and metabolites in nervous tissue. Many processes support neuronal metabolism, and dysregulation of these processes or intrinsic neuronal metabolism is often tied to neurodegenerative diseases. While many techniques are available to query metabolic function and disease (e.g. Seahorse XF, histology, immunostaining), almost all of these approaches are destructive and few offer cellular resolution. However, genetically encoded biosensors can optically measure metabolic features in any tissue with optical access. Biosensors represent an approach to non-destructively monitor metabolic components and regulatory signaling repeatedly …

Mitigating Nonlinear Impairments In High-Speed Optical Communication Systems Via Volterra Nonlinear Equalizer, Safa Jabbar Mohammed, Jalil A. Hamadamin

Polytechnic Journal

This paper presents an in-depth investigation into applying a frequency domain Volterra series nonlinear equalizer (FD-VNLE) to mitigate nonlinear impairments in optical communication systems operating at high speeds. The study aims to address the issues presented by nonlinear effects, specifically self-phase modulation (SPM), which significantly degrades system performance at higher power levels. A comprehensive mathematical model of the FD-VNLE was developed to provide theoretical insight, while its implementation was carried out using MATLAB co-simulated with OptiSystem. The performance of the 40 Gbps dual-polarization quadrature phase shift keying (DP-QPSK) system was rigorously evaluated, focusing on critical performance metrics like bit error …

Contributors, Michaela Velleno

.RAW Journal of Art and Design

No abstract provided.

'The Heart Is A Lonely Hunter' & 'She Burns Quietly', Noir Campbell, Kiana Lee

.RAW Journal of Art and Design

No abstract provided.

'The Cauldron Of Resilience And Doubt' & 'Hopes And Dreams', María Belén Luzuriaga Abad, Samarra Sanders

.RAW Journal of Art and Design

No abstract provided.

'Merry Christmas' & 'Leper's Coil', Grace Franklin, Theo Milner-Hansen

.RAW Journal of Art and Design

No abstract provided.

'Chromatic Dissonance' & 'Tendrils Whisper Me Home', Josh Hakman, Lillie Turinsky

.RAW Journal of Art and Design

No abstract provided.

'The Five Boroughs: A New Yorker's Guide' & 'Here Be Dragons', Teia Kornienko, Jolina Chen

.RAW Journal of Art and Design

No abstract provided.

'Strike Gold' & 'Orpheus Pro', Jenni Martinez, Michaela Velleno

.RAW Journal of Art and Design

No abstract provided.

'Marich Pancrafted Chocolates', Kelli Ayon

.RAW Journal of Art and Design

No abstract provided.

'Labor. (Construcción)' & 'Signs Of Life', Itzel Camarillo-Gonzalez, Owen Isachsen

.RAW Journal of Art and Design

No abstract provided.

'Uchu' & 'Canon Grained', Isabela Cordovez, Savannah Nyulassie

.RAW Journal of Art and Design

No abstract provided.

'Intertwine' & 'The One You Call', Ilona Alves-Denes, Joshua Mahlow

.RAW Journal of Art and Design

No abstract provided.

'Tyler, The Creator' & 'Dots Thrift Store', Nikki Nittianandan, Taz Fruhauf

.RAW Journal of Art and Design

No abstract provided.

'Poly Rodeo '25', Claire Hughes

.RAW Journal of Art and Design

No abstract provided.