Digital Commons Network^™

A Vacuolar Proton Pump Controls The Post-Germinative Growth Of Rice (Oryza Sativa Ssp. Japonica), Peter James Icalia Gann, Soumen Nandy, Rodrigo Botelho, Kari Vinzant, Mariya Khodakovskaya, Vibha Srivastava

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Post-germinative growth in plants is controlled by sucrose mobilization from the endosperm. Regulation of this process, however, is not fully understood. Transcriptional suppression of the rice vacuolar H+ translocating pyrophosphatase (V-PPase) referred to as VPP5 led to enhanced starch content in mature grains. However, vpp5 suppressed lines displayed a slower post-germinative growth rescuable by sucrose, indicating inefficient sucrose mobilization from the endosperm. Biochemical and gene expression analyses showed a slower rate of starch to sucrose conversion and altered expression of the key starch utilization pathway genes. We hypothesized that the modulation of metabolic activities in the vpp5 lines was based …

In Place Of Prison, Grace Y. Li

UC Law Journal

A new, previously unstudied institution is addressing felonies, including violent felonies of the highest levels, without imposing incarceration as the sanction. Attempts to abolish prisons, or at least reduce racialized mass incarceration, must consider how to respond to serious and violent crimes. This Article offers an analysis of a real-world, ongoing experiment in doing so.

The Manhattan Felony Alternative-to-Incarceration Court (“ATI Court”) is the first and, thus far, the only court in the country that systematically offers defendants of any demographic and any charge the opportunity to be diverted from the traditional criminal legal system and to avoid prison. Defendants …

The Law Of Killing For Biodiversity, David Takacs

UC Law Journal

In the United States, Australia, New Zealand, and elsewhere, people kill sentient creatures—by the millions every year—in the crusade to conserve biodiversity.

I explain how laws permit, and in some instances require, killing to save nonhuman species and to keep ecosystems functioning. In Australia, the nation with the worst record of mammalian extinctions, the government has tagged various invaders as “Key Threatening Processes.” In 2023, it laid out elaborate plans to rid the nation of as many feral cats as poison and hunters could kill. Similarly, “Predator Free New Zealand 2050” is the New Zealand government’s elaborate plan to trap …

Artificial Intelligence & Defamation Law: An Excuse To Do Away With The Infamously Controversial Section 230?, Kathryn Binder

UC Law Journal

With the growing prevalence of artificial intelligence (AI) in various aspects of our lives, it is not surprising that it has become a subject of legal disputes and controversy. In 2023, an individual filed the first defamation lawsuit against AI company, OpenAI, for its ChatGPT service, leaving many to speculate how the court will proceed. This Note assesses the viability of defamation actions against generative AI platforms and their broader effect on defamation law. Particularly, this Note considers how courts may characterize these platforms and how specific characterizations could further the controversy over an already polarizing and hotly debated piece …

2025 Annual V.E.S.T Hackathon: Renovating Safety Harnesses, Mason P. Chamberlin

Construction Management

This paper presents the organizational framework and logistical planning involved in executing the 2025 Verifying Everyone’s Safety Together (V.E.S.T.) Hackathon, an annual innovation workshop hosted by the Construction Management Department at California Polytechnic State University, San Luis Obispo. The event brings together students, faculty, and industry professionals to reimagine and redesign common construction equipment with a focus on safety, usability, comfort, and inclusivity across diverse user profiles. The 2025 hackathon, held April 15–16, concentrated on safety harnesses, an essential component of personal protective equipment (PPE) in the construction industry. Participants engaged in the two-day event that included conceptualization, prototyping, and …

Poa Annua Ecology, Biology, And Integrated Weed Management Practices In Turfgrass, David Ervin

Environmental Science and Management Faculty Publications and Presentations

Poa annua L. is one of the most widespread and troublesome weeds of turfgrass. It persists as both an annual and perennial and is adaptable to almost any static maintenance regime, including adaptation to mowing heights and evolution of herbicide resistance. This management guide is intended to provide stakeholders with a summary of new and existing knowledge on integrated Poa annua management. Here we review the basic biology and ecology, as well as practical integrated weed management (IWM) strategies developed for its control.

Increasing Soil Respiration In A Northern Hardwood Forest Indicates Symptoms Of A Changing Carbon Cycle, Angela R. Possinger, Charles T. Driscoll, Mark B. Green, Timothy J. Fahey, Chris E. Johnson, Mary Margaret K. Koppers, Lisa D. Martel, Jennifer L. Morse, Pamela H. Templer, Angelina M. Uribe, Geoffrey F. Wilson, Peter M. Groffman

Environmental Science and Management Faculty Publications and Presentations

Soil carbon dioxide (CO2) flux, or soil respiration, is a critical control on net ecosystem carbon (C) balance. Using long-term (2002-2020) measurements at the Hubbard Brook Experimental Forest (New Hampshire, U.S.), we show that soil respiration rates have notably increased since ~2015. In 2020, cumulative summer respiration flux was approximately 90% higher than the average summer flux over the 2002–2015 period. The increase in soil respiration cannot be explained directly by temperature or pH change alone. We also found that heterotrophic microbial C mineralization and microbial biomass C have also increased rapidly since ~2015, pointing towards an increase in the …

Construction Clothing Development Project, Reed A. Kellar, Noah R. Maytum

Construction Management

Relative to other industries, the construction market is slow to innovate. One clear example of this is in the clothing worn by its workers. Over the past 100 years, construction clothing and top brands have remained largely similar, even as workwear has begun marketing to larger, non-construction audiences. Construction clothing has become increasingly fashionable in popular culture, and we see this as an opportunity. To adapt to a modern world, this entrepreneurial project seeks to research which areas of construction clothing are lacking according to those in the industry and use this data to create a competitive product/brand that capitalizes …

Speech Delay And Hearing Rehabilitation Disparities In Children With Hearing Loss, Lacey C Magee, Malek Bouzaher, Mihika Thapliyal, Yi-Chun Liu, Samantha Anne

Faculty, Staff and Students Publications

Objectives: To investigate the influence of race and insurance type on speech delay rates and hearing rehabilitation access in children with bilateral hearing loss (HL).

Study design: Retrospective cross-sectional study of pediatric patients with bilateral HL who received cochlear implants (CIs) or hearing aids (HAs).

Setting: This study used the national Pediatric Health Information System (PHIS) database to identify patients with HL across 52 tertiary care pediatric hospitals in the United States.

Methods: Data collected included demographics, CI/HA use, speech delay/disorders, and type of insurance coverage.

Results: This study identified 18,422 patients with bilateral HL (40.1% female, 66.3% white, 66.3% …

Stress, Employment Changes, And Psychological Distress Among Caregivers Of Patients With Head And Neck Cancer, Lama Abdurrahman, Vlad C Sandulache, Cielito Reyes-Gibby, Erich M Sturgis, Pavan Jhaveri, Hoda Badr

Faculty, Staff and Students Publications

Importance: Patients undergoing external beam radiation therapy (EBRT) for head and neck cancer (HNC) often experience adverse effects that require substantial caregiving. The burdens of caregiving can impact caregiver employment and mental health over time, yet this topic remains underexplored.

Objective: To examine the associations between caregiving for patients with HNC who undergo EBRT and caregiver stress, employment status, and psychological distress.

Design, setting, and participants: This was a secondary analysis of data from a longitudinal survey study that surveyed caregivers at baseline (ie, at initiation of EBRT) and at 4-month and 12-month follow-ups. The study was conducted at 2 …

Norovirus Replication, Host Interactions And Vaccine Advances, B V Venkataram Prasad, Robert L Atmar, Sasirekha Ramani, Timothy Palzkill, Yongcheng Song, Sue E Crawford, Mary K Estes

Faculty, Staff and Students Publications

Human noroviruses (HuNoVs) are the leading cause of acute gastroenteritis worldwide in all age groups and cause significant disease and economic burden globally. To date, no approved vaccines or antiviral therapies are available to treat or prevent HuNoV illness. Several candidate vaccines are in clinical trials, although potential barriers to successful development must be overcome. Recently, significant advances have been made in understanding HuNoV biology owing to breakthroughs in virus cultivation using human intestinal tissue-derived organoid (or enteroid) cultures, advances in structural biology technology combined with epitope mapping and increased metagenomic sequencing. New and unexpected strain-specific differences in pandemic versus …

Functional Mobility And Pain Are Improved For 6 Years After Adolescent Bariatric Surgery, Neil Thivalapill, Todd M Jenkins, Thomas H Inge, Changchun Xie, Anita P Courcoulas, Carroll M Harmon, Michael A Helmrath, Stephanie Sisley, Marc P Michalsky, Justin R Ryder, Teen‐Longitudinal Assessment Of Bariatric Surgery (Teen‐Labs) Consortium

Faculty, Staff and Students Publications

Objective: The long-term durability of improvements in functional mobility and musculoskeletal pain for adolescents after metabolic and bariatric surgery (MBS) is unknown.

Methods: We used the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study to determine the change in mobility and pain among adolescents who underwent MBS. From standardized 400-m walk tests, we analyzed walk time, heart rate (HR) parameters, and musculoskeletal pain.

Results: The mean walk time improved from 383 s (95% CI: 368-399) prior to surgery to 351 s (95% CI: 330-372) by 6 years. The mean resting HR was 90 beats per minute (bpm; 95% CI: 87-93) preoperatively …

Why Democracy Has Lost The Trust Of Modern People In The Modern Era, Erica Rubel

University Honors Theses

This thesis examines the growing crisis of democratic legitimacy among young people in the 21st century. Across the United States and globally, young people are increasingly disillusioned with formal democratic systems, not because they are disengaged or apathetic, but because they feel systematically excluded from structures that claim to represent them. Through an interdisciplinary framework rooted in political theory, affect studies, intersectionality, and critical media analysis, this research argues that democratic trust cannot be repaired without emotional truth, structural accountability, and reimagined participation.

Drawing on the work of Lipset (1959), Crenshaw (1989), Cohen (2020), Papacharissi (2015), and Spade (2020), this …

Exploring Natural Competence Of Escherichia Coli Through Biofilm Formation, Thulni Liyanaarachchi

University Honors Theses

Escherichia coli is a species not known for natural competence; however, specific growth conditions can induce the process in this bacterium due to the presence of homologous competence genes. These conditions could be met with biofilm formation through an active growth phase in the two-layer architecture. Therefore, my thesis examined whether natural competence is exhibited in E. coli during biofilm formation as determined by the genetic transfer of ampicillin and chloramphenicol-resistance genes between two separate strains. The experiments were broken into three aims to determine the morphology of the biofilm in inter-strain co-cultures and cell-DNA mixes, the effect of …

Penicillin: The Burdensome Physiology Of Β-Lactamase, Lena Uyen-Thi Ngo

University Honors Theses

This thesis is a literature review investigating the effects of overusing penicillin and the nonadherence to proper treatment on the evolutionary changes in a bacterium's resistance. Drawing upon the history, present, and future of penicillin research, the examination analyzes how penicillin came to be, how bacteria developed their resistance, and how scientists are combating this issue. In doing so, the study investigates the historical timeline regarding the discovery of penicillin as an antibiotic. Furthermore, the review will examine the scientific changes within a bacterium's physiology to develop its antibiotic resistance. Finally, the review will delve into what scientists are currently …

Buddy Team 9: The Legacies Of Hiv/Aids Caregiving (New York City, 1990-1993), Jeff Donaldson-Forbes

University Honors Theses

An autoethnographic thesis asks, How were the volunteers of Gay Men's Health Crisis (GMHC) Buddy Team 9 (NYC, circa 1990-1993) impacted by HIV/AIDS caregiving? The author, a former member of GMHC Buddy Team 9, provides context to the HIV/AIDS crisis in a particular era (1990-1993), place (New York City), and cultural setting (via volunteer work supporting a major AIDS service organization).

Is Sharing Always Caring: Critical Discourse Analysis On The Parasociality Of Family Influencing Content On Tiktok, Riley Brown

University Honors Theses

Sharenting, the practice of parents sharing images and information about their children on social media, is a growing, cross-platform phenomenon threatening the privacy and safety of children, especially on TikTok. As this content gained popularity it became monetizable through influencer marketing, or paid partnerships with brands, and created a form of sharenting referred to as family influencing. Influencer marketing encourages the development of parasocial relationships (PSRs) to build a loyal audience for financial success. PSRs develop when a viewer forms a non-reciprocal relationship with a figure through a series of one-sided, mediated interactions simulating face-to-face or intimate interactions. The present …

Playing Makes Believing: Narrative Creation In Tabletop Role-Playing Games, Evan Salthouse

University Honors Theses

Tabletop role-playing games (TTRPGs) are a medium of narrative creation that combine collaborative improvisation, dice rolling, and game mechanics to allow players to tell mythical stories of fantasy and adventure. How are TTRPG systems used to create such memorable, evocative narratives? This research paper analyses Dungeons & Dragons (D&D) 5th Edition, examining its multifaceted system of narrative creation and the forces of influence at play, and outlining how narrative emerges from each aspect of the game. It highlights the act of play as the catalyst for these narratives supported by scholarship of role-playing game studies, and suggests future research investigating …

Not Just An Ad: Exploring Exposure, Persuasion Knowledge, And Health Misinformation On Social Media, Danielle Murray

University Honors Theses

This study explores how exposure to sponsored health and fitness content on social media influences users' perceptions of influencer motivation and belief in health-related misinformation. Drawing on parasocial interaction (PSR), attribution theory, and influencer marketing research, this study investigates two hypotheses: that frequent exposure to branded content is positively associated with (1) perceptions of influencers as commercially motivated and (2) belief in pseudoscientific health myths. A cross-sectional online survey (N = 104) was conducted using convenience sampling of adult social media users. Results partially supported the first hypothesis: exposure frequency was positively correlated with recognition of persuasive intent, but …

Rebellion In The Streets: Activist Art As A Tool For Resistance, Anika Nichols

University Honors Theses

This paper explores the connection between art, anarchism, and Black liberation through the works of Emory Douglas, the AfriCOBRA collective, and Betye Saar. It argues that these artists create a visual language as an expressive form of resistance. One that challenges state violence, capitalist exploitation, and the cultural distortion and marginalization of Black individuals. Framed through anarchist theory, including April Carter's The Political Theory of Anarchism along with writings by Emma Goldman and Lucy Parsons, the project places activist art within a broader tradition of anti-authoritarian ideology. Therefore, by staying rooted in community and rejecting centralized control, these creative practices …

"I Just Kind Of Wish People Knew We Existed:" Rethinking Queer Visibility, Identity, And Belonging In Rural America, Alyson C. Hagen

University Honors Theses

This thesis explores how LGBTQ+ individuals in rural America navigate identity, visibility, and belonging amid the pressures of metronormativity--the dominant cultural narrative that equates queerness with urban life. Through qualitative interviews with five queer adults who lived in rural settings, the study shows that rural queer life is shaped by not only structural erasure and limited resources but also adaptive strategies, emotional labor, and creative community-building. Participants described environments where queerness was often unspoken or denied, yet they developed contingent forms of visibility, online belonging, and grassroots kinship to survive and thrive. Although all participants had migrated to urban areas, …

Alloparenting And Male Infant Care Behaviors In Varecia Rubra (Red-Ruffed Lemur), Noelle Wilcox

University Honors Theses

Nonhuman primates are known for their complex social structures that sometimes includes cooperative breeding strategies. In recent years there has been an increase in investigating alloparenting (infant care provided by an adult or subadult that is not a genetic parent) and male infant care, and how such behaviors contribute to the overall assistance to the extreme energetic investment and costs of the mother for the rearing of offspring. There is also debate to how male care has evolved in the primate clade, be it through the theory of kin selection or theory of mutualism. However, there is not enough research …

Psychometric Properties Of The Spanish Yale-Brown Obsessive-Compulsive Scale - Second Edition, Eric A Storch, Jessica Sc Cheng, Miranda Higham, Josselyn S Muñoz, Vanessa Zavala Cruz, Dayan Berrones, Diana P Obando, Jacey L Anderberg, Renee M Frederick, Vissente Tapia-Cuevas, Macarena Churruca Muñoz, Constanza Uribe Villar, Pablo R Moya, Marcos E Ochoa-Panaifo, Mayra C Martinez Mallen, Andrew D Wiese, Caitlin M Pinciotti, Melisa N Sagarnaga, Joseph F Mcguire, Ogechi C Onyeka, María B Moyano, Latin American Trans-Ancestry Initiative For Ocd Genomics (Latino), Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (Gttoc), Wayne K Goodman, James J Crowley

Faculty, Staff and Students Publications

The Yale-Brown Obsessive-Compulsive Scale, Second Edition (Y-BOCS-II) is an evidence-based clinician-rated measure for assessing the presence and severity of obsessive-compulsive symptoms. The Spanish version of the Y-BOCS-II has not yet been validated. The present study examines the psychometric properties of the Spanish Y-BOCS-II (Spanish-Y-BOCS-II) in adults with obsessive-compulsive disorder (OCD) who are of Hispanic/Latino ancestry. The Spanish-Y-BOCS-II was administered to 1805 adults with OCD. Participants also completed a battery of measures assessing OCD, depression, and anxiety symptoms. The internal consistency for the Symptom Checklist (Kuder-Richardson-20=0.92), Obsession Severity (α=0.87), Compulsion Severity (α=0.86), and Total Severity (α=0.92) were high. The inter-rater reliability …

Interactions Between Adgrf1 (Gpr110) And Extracellular Matrix Proteins Govern Its Effects On Tumorigenesis In Her2-Positive Breast Cancer, Noor Mazin Abdulkareem, Raksha Bhat, Micah Castillo, Sung Yun Jung, Suhas Vasaikar, Sarmistha Nanda, Alexis Ruiz, Martin Shea, Wangjia Cao, Jamunarani Veeraraghavan, Hee-Yong Kim, Tasneem Bawa-Khalfe, Tahir Hussain, Xinli Liu, Preethi Gunaratne, Rachel Schiff, Meghana V Trivedi

Faculty, Staff and Students Publications

Background and purpose: We and others have previously shown that ADGRF1, an adhesion G protein-coupled receptor, is overexpressed and associated with poor survival in many cancers, including human epidermal growth factor receptor-2 (HER2) breast cancer (BC). Also, we have reported the tumour-promoting function of ADGRF1 using preclinical models of HER2+ BC. In this study, we investigated the effect of ADGRF1 overexpression in an orthotopic in vivo model as well as downstream signalling of ADGRF1 in HER2+ BC.

Experimental approach: We utilized a doxycycline (Dox)-induced ADGRF1 overexpression system in HER2+ BC cell lines and performed various in vitro and in vivo …

East Portland Grid: Supporting Clean Industry And Residents, Allison Kirkpatrick, Andrew Azar, Diego Joao Murphy-Mendez, Evan Howington, Kate Carroll, Maura Paxton

Master of Urban and Regional Planning Workshop Projects

Supporting clean industry and residents in ways that are mutually beneficial requires a diversity of efforts. The Columbia Salmonry Group, working for the Portland Bureau of Planning and Sustainability, finds that designating the Sumner-Parkrose-Argay Terrace neighborhoods as a Green Resilient Industrial District (GRID) can, with the following recommendations, build on the work of community and city partners to sustain and grow clean industry in Portland. This area is well suited to be a GRID due to the close proximity of industry and residents, a history of over-planning and under-delivering of investment, and the engaged community. Focusing on the needs of …

A Phenotypic Screen Identifies Xanthohumol And Other Flavonoids As Killers Of Bladder Cancer, Michael J Bolt, Jessica Oceguera, Alejandra Rivera Tostado, Christopher D Candler, Elina Mosa, Kazem Safari, Maureen G Mancini, Michael A Mancini

Faculty, Staff and Students Publications

Bladder cancer accounts for 4 % of cancer diagnoses in the US. Current treatments primarily involve trans-urethral resection of bladder tumors (TURBT) and immunotherapy with Bacille Calmette-Guerin (BCG). Despite the efficacy of TURBT, issues with residual tumors persist. We chose to utilize Cell Painting to screen a set of 244 flavonoid compounds for bladder cancer cell toxicity. Using multiparametric high content analysis termed SPACe, we discover promising candidates underscoring the potential of flavonoids in targeting bladder cancer cells and elucidating their mechanisms of action. Notably, compounds such as xanthohumol show promise in reducing cancer cell viability by altering lipid metabolism. …

Performance Of Stool-Based Molecular Tests And Processing Methods For Paediatric Tuberculosis Diagnosis: A Systematic Review And Meta-Analysis, Lucía Carratalà-Castro, Shilzia Munguambe, Belén Saavedra-Cervera, Petra De Haas, Alexander Kay, Olivier Marcy, Pamela Nabeta, Willy Ssengooba, Elisabetta Ghimenton-Walters, Sozinho Acácio, Maryline Bonnet, Joanna Ehrlich, Andrew R Dinardo, Anca Vasiliu, Christoph Lange, Sabine Hermans, Anna M Mandalakas, Elisa López-Varela, Alberto L García-Basteiro

Faculty, Staff and Students Publications

Background: There has been a global pursuit to improve the diagnosis of tuberculosis in young children by applying diagnostic methods on accessible biospecimens such as stool. We aimed to conduct a systematic review on the accuracy of stool-based molecular tests for tuberculosis diagnosis in children and to assess the impact of the available pre-processing methods and other design characteristics.

Methods: In this systematic review and meta-analysis, we evaluated studies in children younger than 16 years with presumptive tuberculosis that were published in English, Spanish, French, and Portuguese from Jan 1, 2000, to May 3, 2024, in MEDLINE, Embase, and Embase …

Nf2 Loss-Of-Function And Hypoxia Drive Radiation Resistance In Grade 2 Meningiomas, Bhuvic Patel, Sangami Pugazenthi, Collin W English, Vijay Nitturi, Shree S Pari, Tatenda Mahlokozera, William A Leidig, Hsiang-Chih Lu, Alicia Yang, Kaleigh Roberts, Patrick Desouza, Kyle P Mcgeehan, Diane D Mao, Namita Sinha, Joseph E Ippolito, Sonika Dahiya, Allegra Petti, Hiroko Yano, Tiemo J Klisch, Akdes S Harmanci, Akash J Patel, Albert H Kim

Duncan NRI Faculty and Staff Publications

Background: World Health Organization Grade 2 meningiomas (G2Ms) often recur and resist therapies. Grade 2 meningiomas with histopathological necrosis have been associated with worse local control (LC) after radiation therapy, but the drivers and biomarkers of radiation resistance in G2Ms remain unknown.

Methods: We performed genetic sequencing and histopathological analysis of 113 G2Ms and investigated the role of genetic and microenvironmental factors on clonogenic survival after ionizing radiation. We performed transcriptional profiling of our in vitro model and 18 human G2M tumors by bulk RNA sequencing as well as 8 G2Ms by single nuclei RNA sequencing.

Results: NF2 loss-of-function (LOF) …

What Language Are We Speaking?: Marketing Information Literacy On University Library Websites, Aleksandar Golijanin

Communications in Information Literacy

This study investigates how Canadian university libraries communicate information literacy (IL) to non-library faculty members on faculty-facing web pages. A content analysis was conducted of websites from institutions affiliated with the Canadian Association of Research Libraries (n = 25) to identify trends in the terminology used to describe IL. The findings reveal that the term "information literacy" appears with varying frequency across website headings, subheadings and body text, while terms like “research skills” and “critical information use” may appear in its stead. University libraries may intentionally be employing these terms to enhance faculty engagement in response to the existing …

Constraining Nuclear Data Uncertainty Requirements For The 19F(A, N)22Na Reaction For Non-Proliferation Applications, Tyler R. M. Smith

Theses and Dissertations

This thesis explores the requirements on nuclear data uncertainties needed for the use of the ¹⁹F(α, n)²²Na reaction for nuclear non-proliferation applications. An overview of how neutrons are produced from alpha decays in a UF₆ medium is discussed. Calculation demonstrate the role nuclear data uncertainties effect the neutron yield and energy spectra as a function of enrichment.