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Unveiling Social Media Content Related To Adhd Treatment: Machine Learning Study Using X'S Posts Over 15 Years, Alba Gómez-Prieto, Alejandra Mercado-Rodriguez, Juan Pablo Chart-Pascual, Cesar I Fernandez-Lazaro, Francisco J Lara-Abelenda, María Montero-Torres, Claudia Aymerich, Javier Quintero, Melchor Alvarez-Mon, Ana Gonzalez-Pinto, Cesar A Soutullo, Miguel Angel Alvarez-Mon Sep 2025

Unveiling Social Media Content Related To Adhd Treatment: Machine Learning Study Using X'S Posts Over 15 Years, Alba Gómez-Prieto, Alejandra Mercado-Rodriguez, Juan Pablo Chart-Pascual, Cesar I Fernandez-Lazaro, Francisco J Lara-Abelenda, María Montero-Torres, Claudia Aymerich, Javier Quintero, Melchor Alvarez-Mon, Ana Gonzalez-Pinto, Cesar A Soutullo, Miguel Angel Alvarez-Mon

Faculty, Staff and Student Publications

No abstract provided.

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Statice Cut Flower Production In Utah, Kellie Webb, Melanie Stock, Benjamin Scow, Cheyenne Reid, Victoria Xiong, Ali Harrison, Lorin Harrison, Amanda Pratt, Claudia Nischwitz, Nick Volesky Sep 2025

Statice Cut Flower Production In Utah, Kellie Webb, Melanie Stock, Benjamin Scow, Cheyenne Reid, Victoria Xiong, Ali Harrison, Lorin Harrison, Amanda Pratt, Claudia Nischwitz, Nick Volesky

All Current Publications

Statice is a cut-and-come-again, full-sun annual with clustered, papery blooms. Plants have lower water needs and a moderate tolerance to salinity, making this crop a sustainable choice for cut flower production in Utah and other states with water and soil limitations. This fact sheet provides information on statice cultivars, site preparation, germination, transplanting and spacing, trellising, nutrient management, harvest, economics for producers, and pest and disease management.

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Biodiversity Performance Of Living Wall Systems In Temperate Urban Environments: Plant Selection And Substrate Effects On Multi-Taxa Communities: Biodiversity Performance Of Living Wall Systems In Urban Environments, Paul Lunt, Thomas Murphy, James Buckley Sep 2025

Biodiversity Performance Of Living Wall Systems In Temperate Urban Environments: Plant Selection And Substrate Effects On Multi-Taxa Communities: Biodiversity Performance Of Living Wall Systems In Urban Environments, Paul Lunt, Thomas Murphy, James Buckley

School of Geography, Earth and Environmental Sciences

Urban densification threatens biodiversity, yet conventional greenspace expansion is con-strained by limited land availability. Living wall systems (LWS) offer potential biodiversity enhancement through vertical green infrastructure, though their ecological value re-mains underexplored. This study evaluated the biodiversity performance of three LWS in Plymouth, UK, using multi-taxa surveys to assess invertebrate communities, bird assemblages, and bat activity. A scoping review of 2,638 publications revealed limited research on LWS biodiversity, with only 27% of biodiversity-focused papers referencing specific species. Field surveys employed standardized protocols including flower-visiting pollinator observations, spider assessments, soil invertebrate extraction using Tullgren funnels, acoustic bird monitoring, and bat emergence …

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Drawing On Uncertainty Methodologies Of Neutrosophic Hypersoft Sets In Cognitive Computing-Driven Healthcare Systems, Mona Mohamed, Nurhan Alaa Sep 2025

Drawing On Uncertainty Methodologies Of Neutrosophic Hypersoft Sets In Cognitive Computing-Driven Healthcare Systems, Mona Mohamed, Nurhan Alaa

Neutrosophic Systems with Applications

A new paradigm called cognitive computing simulates human reasoning and decision-making through integrating advanced techniques such as artificial intelligence (AI) and natural language processing (NLP). Cognitive computing systems, in contrast to traditional systems, can handle both structured and unstructured data, adjust to new information, and offer context-sensitive insights. This study examines how cognitive computing improves decision-making, personalization, and human-machine collaboration in various fields. Cognitive computing in the healthcare sector processes clinical notes, imaging data, and electronic health records to help physicians with diagnosis, treatment planning, and patient engagement. This study examines key applications, including their role in diagnostic support, where …

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Evaluating And Ranking Genai Chatbots Under Uncertainty: A Type-2 Neutrosophic Rancom–Marcos Mcdm Framework, Hend Ahmed, Abduallah Gamal Sep 2025

Evaluating And Ranking Genai Chatbots Under Uncertainty: A Type-2 Neutrosophic Rancom–Marcos Mcdm Framework, Hend Ahmed, Abduallah Gamal

Neutrosophic Systems with Applications

Owing to integrate GenAI chatbots to enhance productivity across various tasks, this research presents T2NN-RANCOM-MARCOS multi-attribute decision-making model, which employs Type-2 Neutrosophic Number (T2NN) to handle uncertain data, the RANCOM method, distinguished by its easy, highly repeatable, less time consuming, more appropriate to deal with problems exceeds 5 criteria with expert errors to assign subjective weights to criteria and MARCOS method to evaluate and rank eight GenAI chatbots against six main criteria are included 23 sub-criteria: Quality of Information, Understanding and Reasoning, Expression Style and Persona, Safety and Harm, Trust and Confidence and Economic are primarily derived from QUEST evaluation …

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Public Perceptions Of Universities As Public Entities During The Covid-19 Pandemic Era, Jinho Jung, Laura Barrett, Nicole Olynk Widmar, Mario Ortez Sep 2025

Public Perceptions Of Universities As Public Entities During The Covid-19 Pandemic Era, Jinho Jung, Laura Barrett, Nicole Olynk Widmar, Mario Ortez

Department of Agricultural Economics Faculty Publications

Higher education institutions are facing challenges in navigating social, cultural, and political issues. The online presence of higher education presents a new set of opportunities and challenges; knowledge, news, and continuing education are increasingly disseminated online. Additionally, the public, student bodies and stakeholders are increasingly looking at reviews or seeking opinions via online and social media to form opinions on institutions. This analysis uses online and social media to analyze and compare perceptions of two public universities in Indiana, namely Purdue University and Indiana University. These two Indiana institutions are located in the same state, allowing for comparisons of public …

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Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo Sep 2025

Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The lymphatic system is critical to the body's immune and circulatory system, and lymphangiogenesis, the development of new lymphatic vessels from pre-existing ones, is a significant process capitalized upon by cancer during tumorigenesis. Decorin is a small leucine-rich proteoglycan which we have previously shown to be anti-tumorigenic and a suppressor of lymphangiogenesis. We have also shown that decorin exercises its anticancer properties through its ability to evoke autophagy. Through a comprehensive and unbiased proteomic analysis, we explored the implications of decorin exposure on protein expression within mouse lymphatic endothelial cells. We discovered that decorin enriches several protein pathways, notably proteasomal …

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Cookie-Pro: Covalent Inhibitor Binding Kinetics Profiling On The Proteome Scale, Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt, Sung Yun Jung, Bing Zhang, Meng C Wang, Jin Wang Sep 2025

Cookie-Pro: Covalent Inhibitor Binding Kinetics Profiling On The Proteome Scale, Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt, Sung Yun Jung, Bing Zhang, Meng C Wang, Jin Wang

Faculty, Staff and Students Publications

Covalent inhibitors are an emerging class of therapeutics, but methods to comprehensively profile their binding kinetics and selectivity across the proteome have been limited. Here we introduce COOKIE-Pro (COvalent Occupancy KInetic Enrichment via Proteomics), an unbiased method for quantifying irreversible covalent inhibitor binding kinetics on a proteome-wide scale. COOKIE-Pro uses a two-step incubation process with mass spectrometry-based proteomics to determine kinact and KI values for covalent inhibitors against both on-target and off-target proteins. We validated COOKIE-Pro using BTK inhibitors spebrutinib and ibrutinib, accurately reproducing known kinetic parameters and identifying both expected and unreported off-targets. The method revealed that …

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Engineered Exosomes With Krasg12d Specific Sirna In Pancreatic Cancer: A Phase I Study With Immunological Correlates, Valerie S Kalluri, Brandon G Smaglo, Krishnan K Mahadevan, Michelle L Kirtley, Kathleen M Mcandrews, Mayela Mendt, Sujuan Yang, Ana S Maldonado, Hikaru Sugimoto, Maria E Salvatierra, Luisa M Solis Soto, Cara Haymaker, Rick Finch, Mihai Gagea, Adam C Fluty, Steven J Ludtke, J Jack Lee, Abhinav K Jain, Gauri Varadhachary, Rachna T Shroff, Anirban Maitra, Elizabeth Shpall, Shubham Pant, Raghu Kalluri Sep 2025

Engineered Exosomes With Krasg12d Specific Sirna In Pancreatic Cancer: A Phase I Study With Immunological Correlates, Valerie S Kalluri, Brandon G Smaglo, Krishnan K Mahadevan, Michelle L Kirtley, Kathleen M Mcandrews, Mayela Mendt, Sujuan Yang, Ana S Maldonado, Hikaru Sugimoto, Maria E Salvatierra, Luisa M Solis Soto, Cara Haymaker, Rick Finch, Mihai Gagea, Adam C Fluty, Steven J Ludtke, J Jack Lee, Abhinav K Jain, Gauri Varadhachary, Rachna T Shroff, Anirban Maitra, Elizabeth Shpall, Shubham Pant, Raghu Kalluri

Faculty, Staff and Students Publications

Oncogenic KRAS is amongst the key genetic drivers for initiation and maintenance of pancreatic ductal adenocarcinoma (PDAC). Here, we show that engineered exosomes with KrasG12D specific siRNA (iExoKrasG12D) reveal a biodistribution in pancreas with negligible toxicity in preclinical studies in mice and Rhesus macaques. Clinical testing of iExoKrasG12D in the iEXPLORE (iExoKrasG12D in Pancreatic Cancer) Phase I study employed a non-randomized single-arm classical 3 + 3 dose escalation design (Phase Ia), followed by an accelerated titration design (Phase Ib) (NCT03608631). The primary outcomes included safety, tolerability and target engagement, and the secondary outcomes aimed to assess disease control. …

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The Effect Of Pesticide Exposure On Metabolic Syndrome: An Epidemiological Analysis In An Agricultural Population, Putri Arida Ipmawati, Rusmiati Rusmiati, Suharno Suharno, Tommy Denie Irianto, Alfino Validita Sidiq, Abentin Estim, Slamet Wardoyo Sep 2025

The Effect Of Pesticide Exposure On Metabolic Syndrome: An Epidemiological Analysis In An Agricultural Population, Putri Arida Ipmawati, Rusmiati Rusmiati, Suharno Suharno, Tommy Denie Irianto, Alfino Validita Sidiq, Abentin Estim, Slamet Wardoyo

Media Kesehatan Masyarakat Indonesia

Metabolic syndrome, characterised by hyperglycaemia, dyslipi-daemia, hypertension, and central obesity, is a global health problem, and exposure to pesticides is an important risk factor for agricultural workers. This study aims to analyse the effects of pesticide exposure, sociodemographic factors, and Personal Protective Equipment (PPE) usage behaviour on glucose levels, HDL, and LDL in farmers in Kubu Raya District, West Kalimantan. A cross-sectional study was conducted on 60 farmers selected using stratified random sampling. Data were collected through structured interviews, fasting blood tests, and analysed using the chi-square test with a significance level of 95%. The results showed a high prevalence …

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Rethinking School Nutrition Via Community Engagement: A Review With Implications For Indonesia’S Mbg Program, Adnan Achiruddin Saleh, Suparman Abdullah, Rahmat Muhammad, Muhammad Yusran Amir, Sulvinajayanti Sulvinajayanti Sep 2025

Rethinking School Nutrition Via Community Engagement: A Review With Implications For Indonesia’S Mbg Program, Adnan Achiruddin Saleh, Suparman Abdullah, Rahmat Muhammad, Muhammad Yusran Amir, Sulvinajayanti Sulvinajayanti

Media Kesehatan Masyarakat Indonesia

Community engagement has become a growing concern in the implementation of school nutrition programs, particularly in addressing issues of child malnutrition, food insecurity, and educational outcomes. However, definitions and levels of participation remain conceptually fragmented across various studies. This study aims to systematically review the scope, forms, and implications of community engagement in school-based nutrition programs. A Systematic Literature Review (SLR) was conducted on 89 Scopus-indexed publications from 1984 to 2025 using the PRISMA 2020 protocol. Thematic analysis was employed to identify the conceptual, methodological, and contextual variations of community involvement. Data were collected through document analysis of peer-reviewed journal …

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Cost-Effectiveness And Feasibility Of Anemia Management In Pregnant Women: A Systematic Review, Della Winanti, Isra Yanti, Nurul Fitriyah, Sirajul Munira, Mufdlillah Mufdlillah, Firdaus Hafidz Sep 2025

Cost-Effectiveness And Feasibility Of Anemia Management In Pregnant Women: A Systematic Review, Della Winanti, Isra Yanti, Nurul Fitriyah, Sirajul Munira, Mufdlillah Mufdlillah, Firdaus Hafidz

Media Kesehatan Masyarakat Indonesia

Anemia among expectant mothers is a major health issue worldwide, especially in developing countries, where prevalence reaches 37%. Various interventions, such as micronutrient supplementation and intravenous iron administration, have been widely implemented. However, limited systematic reviews have comprehensively evaluated both the cost-effectiveness and feasibility of such interventions in low- and middle-income countries (LMICs). This study aims to systematically evaluate recent evidence on the feasibility and cost-effectiveness of anemia management interventions for pregnant women in developing countries. The review followed the 2020 PRISMA guidelines and was registered in PROSPERO (CRD420251089753). Article searches were conducted across five primary databases (CINAHL, CENTRAL, PubMed, …

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Multivariate Analysis Of Risk Factors For Destructive Behavior In Children In Indonesia, Nany Hairunisa, Husnun Amalia, Agnes Tineke Waney Rorong, Yasmine Mashabi, Muhammad Amru Hammam El Putra, Asrenee Ab. Razak Sep 2025

Multivariate Analysis Of Risk Factors For Destructive Behavior In Children In Indonesia, Nany Hairunisa, Husnun Amalia, Agnes Tineke Waney Rorong, Yasmine Mashabi, Muhammad Amru Hammam El Putra, Asrenee Ab. Razak

Media Kesehatan Masyarakat Indonesia

Conduct disorders pose a significant global burden, affecting an estimated 5.75 million children and adolescents, especially boys. Conduct disorders involve repetitive behaviors that violate others rights and can jeopardize normal relationships between children and those around them. Major behavioral issues in children often occur in both school and family settings and are closely linked to the roles of parents and teachers as educators and guides. Additionally, children at a young age are highly curious and eager to explore new things; the rapid growth of technology introduces new challenges for them. Without parental guidance, considering factors such as parenting styles, education …

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Clustering Community Risk Behaviors For Non-Communicable Diseases In Indonesia: Based On Indonesian Health Survey Data, Hanif Pandu Suhito, Mahalul Azam, Dina Nur Anggraini Ningrum, Sholikun Sholikun Sep 2025

Clustering Community Risk Behaviors For Non-Communicable Diseases In Indonesia: Based On Indonesian Health Survey Data, Hanif Pandu Suhito, Mahalul Azam, Dina Nur Anggraini Ningrum, Sholikun Sholikun

Media Kesehatan Masyarakat Indonesia

Non-communicable Diseases (NCDs) such as hypertension, stroke, diabetes mellitus, and heart disease are major causes of morbidity and mortality in Indonesia. Community behaviors, including smoking, low physical activity, and unhealthy diets, significantly influence NCD incidence. To analyze associations between behavioral risk factors (daily smoking, physical inactivity, consumption of sugary foods and drinks, salty foods, fatty foods, soft drinks, and inadequate fruit intake) and the prevalence of NCDs, and to classify regions based on risk factors and disease prevalence. A cross-sectional study was conducted using secondary data from the 2023 Indonesian Health Survey (IHS), encompassing 345,000 households across 39 provinces. The …

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Indoor Air Quality And Sick Building Syndrome In Selected Public Buildings In Shah Alam, Selangor, Ismaniza Ismail, Mohamad Solehin Zulkarnain, Ilyas Syafiq Darul Ridzuan, Yahya Thamrin, Nasrul Hamidin Sep 2025

Indoor Air Quality And Sick Building Syndrome In Selected Public Buildings In Shah Alam, Selangor, Ismaniza Ismail, Mohamad Solehin Zulkarnain, Ilyas Syafiq Darul Ridzuan, Yahya Thamrin, Nasrul Hamidin

Media Kesehatan Masyarakat Indonesia

Indoor Air Quality (IAQ) is always associated with Sick Building Syndromes (SBS) despite the age of the buildings, particularly in buildings where indoor air pollutants may affect occupants’ health and productivity. This study assessed IAQ parameters and SBS symptoms in five selected public buildings aged 10 and above in Shah Alam, Selangor. Physical, chemical and biological parameters were measured, while structured questionnaires were completed by 87 respondents occupying the buildings. Most IAQ parameters were within the ranges of the Industry Code of Practice on IAQ (ICOP IAQ 2010), except for air velocity, formaldehyde and Total Volatile Organic Compound (TVOC) in …

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Understanding Cardiovascular Risk: Insights From Coastal Communities In Southeast Sulawesi, Syahrianti Syahrianti, Lilin Rosyanti, Reni Revianti Usman, Ismail Ismail, Agus Bintara Birawida, Sumarheni Sumarheni, Muhammad Fahmi Aziz Sep 2025

Understanding Cardiovascular Risk: Insights From Coastal Communities In Southeast Sulawesi, Syahrianti Syahrianti, Lilin Rosyanti, Reni Revianti Usman, Ismail Ismail, Agus Bintara Birawida, Sumarheni Sumarheni, Muhammad Fahmi Aziz

Media Kesehatan Masyarakat Indonesia

Cardiovascular Disease (CVD) remains the leading cause of death worldwide, with a greater impact on low- and middle-income countries, particularly coastal communities that depend on fragile ecosystems. This study explores the effects of sociodemographic, behavioral, and metabolic factors on CVD incidence among the coastal population of Soropia, Konawe, Southeast Sulawesi. This research employs a quantitative approach with a cross-sectional design and applies Structural Equation Modeling (SEM) using Smart PLS software. Data collection was conducted through standardized questionnaires and physical examinations. The findings reveal that age significantly reduces CVD risk (p = 0.043, Exp(B) = 0.378), while gender and occupation show …

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Understanding The Impact Of Pictorial Health Warnings On Smoking Behavior Among Adolescents, Pandji Winata Nurikhwan, Hadrianti Haji Darise Lasari, Dessy Maulina, Mustafa Mustafa, Abdillah Ahsan, Anis Kamila Saleha, Indra Haryanto Ali Sep 2025

Understanding The Impact Of Pictorial Health Warnings On Smoking Behavior Among Adolescents, Pandji Winata Nurikhwan, Hadrianti Haji Darise Lasari, Dessy Maulina, Mustafa Mustafa, Abdillah Ahsan, Anis Kamila Saleha, Indra Haryanto Ali

Media Kesehatan Masyarakat Indonesia

Smoking behavior remains a health challenge in Indonesian society. Riskesdas data shows an increase in smoking prevalence in adolescent groups. One of the control efforts is the implementation of PHW (Pictorial Health Warnings) on cigarette packs in accordance with Permenkes RI No. 28 of 2013. This study aims to determine the effectiveness of cigarette packs in influencing smoking intention and behavior PHW among adolescents in Tanah Bumbu Regency, Banjarbaru City and Banjarmasin City. The study used a quantitative method with a cross-sectional design. Samples were obtained through an accidental sampling technique, obtaining 315 smoking adolescents and 62 non-smoking adolescents. The …

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Relationship Between Cadres Knowledge And Ability To Document Arumdalu Integrated Service Posts (Posyandu) Information System Reports, Devi Pramita Sari, Andi Zulkifli Sep 2025

Relationship Between Cadres Knowledge And Ability To Document Arumdalu Integrated Service Posts (Posyandu) Information System Reports, Devi Pramita Sari, Andi Zulkifli

Media Kesehatan Masyarakat Indonesia

The high demands of administration and activities report at Integrated Service Posts (Posyandu) requiring cadres skills in documenting data accurately. In this field, the reality shows that many cadres lack adequate knowledge regarding. The Posyandu information system, especially the Arumdalu Posyandu. Therefore, this study aimed to determine the relationship between cadres' knowledge and ability to document reports on the Arumdalu Posyandu information system. The quantitative analytical research design used a cross-sectional, longitudinal (pre-post digital training), and mixed methods approach, complemented by Social Network Analysis (SNA). The research sample consisted of 60 Posyandu cadres at the Arumdalu Posyandu …

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Adaptation Of Moringa Leaf Extract On Hemoglobin And Arm Circumference In Adolescent Girls Semarang, Sri Achadi Nugraheni, Ari Yuniastuti, Suryani As’Ad, Pingkan Fristiwi, Fatimah Asri Fadhilah Aulia, Shafa Alya Kamila Sep 2025

Adaptation Of Moringa Leaf Extract On Hemoglobin And Arm Circumference In Adolescent Girls Semarang, Sri Achadi Nugraheni, Ari Yuniastuti, Suryani As’Ad, Pingkan Fristiwi, Fatimah Asri Fadhilah Aulia, Shafa Alya Kamila

Media Kesehatan Masyarakat Indonesia

Adolescent malnutrition, particularly anemia, remains a major public health challenge in developing countries, including Indonesia, as it increases the risk of growth retardation, developmental disorders, poor pregnancy outcomes, and infectious diseases. Nutritional interventions during adolescence are crutial for improving health and breaking the intergenerational cycle of malnutrition. This study aimed to analyze the effect of Moringa oleifera capsules on hemoglobin (Hb) levels and Mid-Upper Arm Circumference (MUAC) among adolescent girls in Semarang. A quasi-experimental study with a pretest–posttest control group design was conducted in two junior high schools in Semarang (SMPN 39 and SMPN 8), involving 102 female students aged …

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Ebola Virus Vp35 Nnlns Motif Modulates Viral Rna Synthesis And Mib2-Mediated Signaling, Grace Uwase, Priya Luthra, Olivia A Vogel, Jyoti Batra, Bruno A La Rosa, Kathleen C F Sheehan, Oam Khatavkar, Jacqueline E Payton, Robert A Davey, Nevan J Krogan, Christopher F Basler, Daisy W Leung, Gaya K Amarasinghe Sep 2025

Ebola Virus Vp35 Nnlns Motif Modulates Viral Rna Synthesis And Mib2-Mediated Signaling, Grace Uwase, Priya Luthra, Olivia A Vogel, Jyoti Batra, Bruno A La Rosa, Kathleen C F Sheehan, Oam Khatavkar, Jacqueline E Payton, Robert A Davey, Nevan J Krogan, Christopher F Basler, Daisy W Leung, Gaya K Amarasinghe

2020-Current year OA Pubs

Ebola virus (EBOV) is a nonsegmented, negative-sense virus (NNSV) with a single-stranded RNA genome. EBOV encodes for a limited number of proteins and thus depends on host factors to facilitate viral replication and pathogenesis. Of the virus-encoded proteins, multifunctional EBOV VP35 (eVP35) is necessary for host immune evasion and viral RNA synthesis. Previous proteomics studies identified an interaction between eVP35 and the host E3 ubiquitin ligase Mindbomb 2 (MIB2). Here, we show how an NNLNS (Asn-Asn-Leu-Asn-Ser) motif (residues 201 to 205) within eVP35 serves as a binding site for MIB2. This motif is critical for eVP35-dependent inhibition of MIB2-mediated interferon …

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Long-Acting Recombinant Il-7 (Rhil-7-Hyfc) Enhances The Primary And Memory Neoantigen-Specific Immune Response To Breast Cancer Personalized Cancer Vaccines, Michael Chen, Thomas Kane, Ina Chen, Suangson Supabphol, Xiuli Zhang, Alexandra A Wolfarth, Donghoon Choi, Lijin Li, S Peter Goedegebuure, William E Gillanders Sep 2025

Long-Acting Recombinant Il-7 (Rhil-7-Hyfc) Enhances The Primary And Memory Neoantigen-Specific Immune Response To Breast Cancer Personalized Cancer Vaccines, Michael Chen, Thomas Kane, Ina Chen, Suangson Supabphol, Xiuli Zhang, Alexandra A Wolfarth, Donghoon Choi, Lijin Li, S Peter Goedegebuure, William E Gillanders

2020-Current year OA Pubs

No abstract provided.

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Development Of A Leucine-Rich Repeat-Containing Protein 15-Targeted Radio-Immunotheranostic Approach To Deplete Pro-Tumorigenic Mechanisms And Immunotherapy Resistance, Claire M Storey, Abbie Hasson, Diane Abou, Daniel Thorek, Et Al. Sep 2025

Development Of A Leucine-Rich Repeat-Containing Protein 15-Targeted Radio-Immunotheranostic Approach To Deplete Pro-Tumorigenic Mechanisms And Immunotherapy Resistance, Claire M Storey, Abbie Hasson, Diane Abou, Daniel Thorek, Et Al.

2020-Current year OA Pubs

Leucine-rich repeat containing 15 (LRRC15) has emerged as an attractive biomarker and target for cancer therapy. Transforming growth factor-β (TGFβ) induces the expression of this plasma membrane protein specifically in aggressive and treatment resistant tumor cells derived from mesenchymal stem cells, with minimal expression observed in non-neoplastic tissues. We have developed a humanized monoclonal antibody, DUNP19, that specifically binds with high affinity to a phylogenetically conserved LRRC15 epitope and is rapidly internalized upon LRRC15 binding. In multiple subcutaneous and orthotopic tumor xenograft mouse models, Lutetium-177 labeled DUNP19 ([

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“Better Safe Than Sorry”: Exploring The Experiences Of Malaysian Parents On Sharenting, Ireena Nasiha Ibnu, Tengku Elena Tengku Mahamad, Zaridah Abdullah Dollah, Massila Hamzah, Nor Hazlina Binti Hashim Sep 2025

“Better Safe Than Sorry”: Exploring The Experiences Of Malaysian Parents On Sharenting, Ireena Nasiha Ibnu, Tengku Elena Tengku Mahamad, Zaridah Abdullah Dollah, Massila Hamzah, Nor Hazlina Binti Hashim

Asia-Pacific Social Science Review

This research explores the experiences of Malaysian parents concerning their children’s privacy and their sharenting habits in the digital age. Sharenting, the practice of sharing information about one’s children on social media, has become prevalent, raising concerns about privacy and potential risks. Through qualitative exploration, this study investigates how Malaysian parents strike a balance between sharing meaningful moments online and ensuring the safety and privacy of their children. Two focus group discussions were conducted via Zoom with 15 Malaysian parents. The central theme that emerges from this study revolves around the delicate balance between parental expression and safeguarding children’s privacy. …

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Ethical Technology Assessment Of Artificial Intelligence (Ai) And The Internet Of Things (Iot) Among Gen Z Population In Thailand And The Philippines, Melvin Jabar, Penchan Pradubmook Sherer, Seung Chun Paek, Elena Chiong-Javier Sep 2025

Ethical Technology Assessment Of Artificial Intelligence (Ai) And The Internet Of Things (Iot) Among Gen Z Population In Thailand And The Philippines, Melvin Jabar, Penchan Pradubmook Sherer, Seung Chun Paek, Elena Chiong-Javier

Asia-Pacific Social Science Review

With the use of the ethical technology assessment model by Palm and Hansson (2006), this paper examines the knowledge and perceptions about the ethics of and experiences with artificial intelligence (AI) and the internet of things (IoT) among the Generation Z population in Thailand and the Philippines. A total of 1,060 Thai and 1,499 Filipino Gen Z students participated in the online survey. Results revealed that Gen Z respondents from Thailand and the Philippines muse heavily on privacy, social contact, autonomy and control, as well as human reproduction and health issues. Moreover, both groups are most bothered by the potential …

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Electronic Device Usage During Covid-19 And Suspected Developmental Delay In Rural Thai Children: A Case-Control Study, Kunnara Maneekunwong, Pimkanabhon Trakooltorwong, Salisa Kodyee, Nathamon Wutthipan, Chompunut Sopajaree, Katemanee Moonpanane Sep 2025

Electronic Device Usage During Covid-19 And Suspected Developmental Delay In Rural Thai Children: A Case-Control Study, Kunnara Maneekunwong, Pimkanabhon Trakooltorwong, Salisa Kodyee, Nathamon Wutthipan, Chompunut Sopajaree, Katemanee Moonpanane

Asia-Pacific Social Science Review

The COVID-19 pandemic has significantly altered the way in which people interact with and use technology, particularly in early childhood. This study investigated the relationship between electronic device usage during the COVID-19 pandemic in rural Thailand and suspected developmental delay (SDD) in early childhood. A case-control study aimed to investigate the relationship between suspected SDD and electronic device usage among children aged 2–5 and their primary caregivers in Chiang Rai province, Thailand. The cases were children with SDD, whereas the controls were children with age-appropriate development. The Developmental Surveillance and Promotion Manual (DSPM) and the Screen Media Exposure (SME) questionnaire …

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(Gendered) Transcultural Capital And Memory In Zahid Hussain’S The Curry Mile (2006), Dhanya V. Sankar, Sarbani Banerjee Sep 2025

(Gendered) Transcultural Capital And Memory In Zahid Hussain’S The Curry Mile (2006), Dhanya V. Sankar, Sarbani Banerjee

Asia-Pacific Social Science Review

Transcultural memory intertwines with transnationality, integrating decolonial paradigms into the making of a plurality of cultures. Drawing from Astrid Erll’s conceptualization of “travelling memory,” the “migrant memories” are always in kinesis and cannot be pinned down to a singular geographic location or culture. Instead, they facilitate active engagement with the host nation. Zahid Hussain, a British Pakistani author, captures this dynamic in his novel, The Curry Mile (2006), which portrays the aspirations of second-generation migrant Sorayah Butt, a woman in her 20s battling several personal and cultural issues when she decides to step in for her father, who is losing …

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Characteristics And Frequency Of Use Of People Who Use Cannabis In Thailand: Results From A Web-Based Survey, Francois R. Lamy, Seung Chun Paek, Natthani Meemon Sep 2025

Characteristics And Frequency Of Use Of People Who Use Cannabis In Thailand: Results From A Web-Based Survey, Francois R. Lamy, Seung Chun Paek, Natthani Meemon

Asia-Pacific Social Science Review

In the past two decades, the medical and recreational use of cannabis has been linked to an increase in cannabis- related harms, especially among frequent cannabis users. Amid the recent legalization of recreational use of cannabis in Thailand, this paper provides initial information regarding the frequency of usage, sociodemographic characteristics, reasons and patterns of cannabis use, as well as the characteristics associated with frequent usage among people who use cannabis. A cross-sectional anonymous online survey was conducted (July-August 2022) with 476 Thais who use cannabis recruited via the Line and Facebook apps. Descriptive statistics and multiple logistic regression analysis were …

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Automated Video Production Workflow Using Textual Source Documents, Kumar Dhanagopal Sep 2025

Automated Video Production Workflow Using Textual Source Documents, Kumar Dhanagopal

Defensive Publications Series

This disclosure describes a multi-stage workflow to facilitate automated video production from textual source documents. A system may process source documents to generate a narrative audio track. This audio can then be analyzed by a computing system to produce a corresponding visual storyboard, for example, by identifying concepts and scenes. Based on information from this storyboard, generative tools may be used to create multimedia assets, such as graphics and video clips. The generated audio and visual components may then be assembled into a video. This integrated method provides a process for converting text to video that can potentially reduce manual …

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Automatic Integration Of Temporal Context For Large Language Models, Na Sep 2025

Automatic Integration Of Temporal Context For Large Language Models, Na

Defensive Publications Series

Current LLMs struggle with real-time knowledge, tracking elapsed time, chronological context, and generating time-sensitive responses, leading to user burden and limited applicability in time-sensitive domains. This disclosures describes techniques for integrating real-time temporal context into large language model (LLM) processing of user queries, addressing their inherent lack of temporal awareness. The techniques described herein automatically obtain current time from a reliable time source as well as relevant temporal context such as conversation history between an LLM-powered chatbot and a user that provides a query. The time information together with the user query is provided to the LLM which can thereby …

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Target Markets 2024–2030 For Ai Products, Xavier Pillet Sep 2025

Target Markets 2024–2030 For Ai Products, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of ChatGPT o3 and ChatGPT 5 Thinking, is released under the Apache 2.0 licence. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes: (art. L 611-11 CPI / art. 54(2) CBE), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (中华人民共和国专利法), and Japanese Patent Act Art. 29(1) (特許法). It consolidates 80 reproducible technical contributions across software, sensors, hardware, AI, protocols, materials, manufacturing, imaging, delivery, therapies, data/privacy, UX/workflows, supply chain and business processes. Each item is described in an enabling …

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