Digital Commons Network^™

Learning Curve For Endoscopic Submucosal Dissection (Esd) In The United States: Large, Untutored, Single-Operator Experience, Mai A Khalaf, Fares Ayoub, Kristen A Staggers, Johanna W El-Haj, Salmaan Jawaid, Mohamed O Othman

Faculty, Staff and Students Publications

Background and study aims Endoscopic submucosal dissection (ESD) allows removal of tumors en-bloc. Western adoption of ESD has been hindered by its steep learning curve. Western data regarding ESD learning curve are limited. We analyzed the learning curve of a single endoscopist at a tertiary referral center in the United States.

Patients and methods All consecutive ESDs performed by a single endoscopist at a tertiary referral center in the United States from 2015 through 2022 were identified. Descriptive statistics and CUSUM analysis were used to describe the learning curve for en-bloc, R0 resection, and resection speed.\

Results In our study, …

Anticoagulant Medications: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Collaborative Consensus Conference, Katherine Cashen, Arun Saini, Leonardo R Brandão, Jennifer Le, Paul Monagle, Katie M Moynihan, Lindsay M Ryerson, Alison Gehred, Elizabeth Lyman, Jennifer A Muszynski, Peta M A Alexander, Heidi J Dalton

Faculty, Staff and Students Publications

OBJECTIVES: To derive systematic-review informed, modified Delphi consensus regarding the medications used for anticoagulation for pediatric extracorporeal membrane oxygenation (ECMO) for the Pediatric ECMO Anticoagulation CollaborativE (PEACE).

DATA SOURCES: A structured literature search was performed using PubMed, EMBASE, and Cochrane Library (CENTRAL) databases from January 1988 to May 2021.

STUDY SELECTION: Included studies assessed anticoagulation used in pediatric ECMO.

DATA EXTRACTION: Two authors reviewed all citations independently, with a third reviewer adjudicating any conflicts. Eighteen references were used for data extraction as well as for creation of recommendations. Evidence tables were constructed using a standardized data extraction form.

DATA SYNTHESIS: …

Management Of Extracorporeal Membrane Oxygenation Anticoagulation In The Perioperative Period: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Collaborative Consensus Conference, Ariane Willems, Marc M Anders, Alejandro V Garcia, Adam M Vogel, Andrew R Yates, Jennifer A Muszynski, Peta M A Alexander, Katherine Steffen, Sitaram Emani, Alison Gehred, Elizabeth Lyman, Lakshmi Raman

Faculty, Staff and Students Publications

OBJECTIVES: To derive systematic review-informed, modified Delphi consensus regarding the management of children on extracorporeal membrane oxygenation (ECMO) undergoing invasive procedures or interventions developed by the Pediatric Anticoagulation on ECMO CollaborativE (PEACE) Consensus Conference.

DATA SOURCES: A structured literature search was performed using PubMed, EMBASE, and Cochrane Library (CENTRAL) databases from January 1988 to May 2021.

STUDY SELECTION: ECMO anticoagulation and hemostasis management in the perioperative period and during procedures.

DATA EXTRACTION: Two authors reviewed all citations independently, with a third independent reviewer resolving any conflicts. Seventeen references were used for data extraction and informed recommendations. Evidence tables were constructed …

Priorities For Clinical Research In Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Collaborative Consensus Conference, Jennifer A Muszynski, Melania M Bembea, Alison Gehred, Elizabeth Lyman, Katherine Cashen, Ira M Cheifetz, Heidi J Dalton, Adam S Himebauch, Oliver Karam, Katie M Moynihan, Marianne E Nellis, Caroline Ozment, Lakshmi Raman, Natalie E Rintoul, Ahmed Said, Arun Saini, Marie E Steiner, Ravi R Thiagarajan, Kevin Watt, Ariane Willems, Nicole D Zantek, Ryan P Barbaro, Katherine Steffen, Adam M Vogel, Peta M A Alexander

Faculty, Staff and Students Publications

OBJECTIVES: To identify and prioritize research questions for anticoagulation and hemostasis management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation CollaborativE (PEACE) consensus.

DATA SOURCES: Systematic review was performed using PubMed, EMBASE, and Cochrane Library (CENTRAL) databases from January 1988 to May 2021, followed by serial consensus conferences of international, interprofessional experts in the management of ECMO for critically ill neonates and children.

STUDY SELECTION: The management of ECMO anticoagulation for critically ill neonates and children.

DATA EXTRACTION: Within each of the eight subgroups, two authors reviewed all citations independently, with a third …

Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation Collaborative (Peace) Consensus Conference, Peta M A Alexander, Melania M Bembea, Katherine Cashen, Ira M Cheifetz, Heidi J Dalton, Adam S Himebauch, Oliver Karam, Katie M Moynihan, Marianne E Nellis, Caroline Ozment, Lakshmi Raman, Natalie E Rintoul, Ahmed S Said, Arun Saini, Marie E Steiner, Ravi R Thiagarajan, Kevin Watt, Ariane Willems, Nicole D Zantek, Ryan P Barbaro, Katherine Steffen, Adam M Vogel, Christopher Almond, Marc M Anders, Gail M Annich, Leonardo R Brandão, Wayne Chandler, Megan Delaney, Robert Digeronimo, Sitaram Emani, Samir K Gadepalli, Alejandro V Garcia, Bereketeab Haileselassie, Robert Hyslop, Martin C J Kneyber, Lisa Baumann Kreuziger, Jennifer Le, Laura Loftis, Ali B V Mcmichael, D Michael Mcmullan, Paul Monagle, Kathleen Nicol, Matthew L Paden, Jason Patregnani, John Priest, Leslie Raffini, Lindsay M Ryerson, Steven R Sloan, Jun Teruya, Andrew R Yates, Alison Gehred, Elizabeth Lyman, Jennifer A Muszynski

Faculty, Staff and Students Publications

OBJECTIVES: To present recommendations and consensus statements with supporting literature for the clinical management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation CollaborativE (PEACE) consensus conference.

DATA SOURCES: Systematic review was performed using PubMed, Embase, and Cochrane Library (CENTRAL) databases from January 1988 to May 2021, followed by serial meetings of international, interprofessional experts in the management ECMO for critically ill children.

STUDY SELECTION: The management of ECMO anticoagulation for critically ill children.

DATA EXTRACTION: Within each of eight subgroup, two authors reviewed all citations independently, with a third independent reviewer resolving any …

Progressive Thrombocytopenia, Splenomegaly, And Abnormal Tone In An Infant With Growth Faltering, Gal Barak, Gail Demmler-Harrison, Linda Rossetti, Venée N Tubman, Ameya S Walimbe, Rathi Asaithambi

Faculty, Staff and Students Publications

A 4-month-old full-term female presented with growth faltering associated with progressive feeding difficulty, rash, abdominal distension, and developmental delays. She was found to have disconjugate gaze, abnormal visual tracking, mixed tone, bruising, and splenomegaly on examination. Initial workup was notable for thrombocytopenia and positive cytomegalovirus (CMV) immunoglobulin G and immunoglobulin M antibodies. She initially presented to the infectious diseases CMV clinic, where she was noted to have severe malnutrition, prompting referral to the emergency department for hospital admission to optimize nutrition with nasogastric tube feeding and facilitate additional evaluation. An active CMV infection with viruria and viremia was confirmed, but …

Subspecialty Choices Among Medicine-Pediatrics Graduates: Results From A Four-Year National Program Director Survey, Anoop Agrawal, Daniel Wells, Michael Kisielewski, Savita Misra, Benjamin Doolittle

Faculty, Staff and Students Publications

Background and objectives Dual-trained medicine-pediatrics physicians (med-peds) play an important role in the healthcare ecosystem. Little is known about the subspecialty choices of med-peds residency graduates. This study aims to characterize the subspecialty choices of med-peds residency graduates. Methods The Medicine-Pediatrics Program Directors Association (MPPDA) administers an annual survey to the program directors of all med-peds residency programs accredited by the Accreditation Council for Graduate Medical Education (ACGME). This project represents aggregate survey data from 2020-2023. Results The number of program directors responding to the survey ranged from 80.8% (63/78) to 85.7% (66/77; mean response rate: 82.8%). About 465 of …

Dyspneic And Pink, Christian Inchaustegui, Sarvari Yellapragada, Jack Badawy, Ameer Ahmed, Andrew White, Zaven Sargsyan

Faculty, Staff and Students Publications

No abstract provided.

Patient Perspectives On Using Telemedicine During In-Center Hemodialysis: A Qualitative Study, Trenton M Haltom, Susie Q Lew, Wolfgang C Winkelmayer, Glenn M Chertow, Allison Jaure, Kevin F Erickson

Faculty, Staff and Students Publications

RATIONALE & OBJECTIVE: In the wake of the coronavirus disease 2019 (COVID-19) pandemic, the United States federal government expanded originating telemedicine sites to include outpatient dialysis units. For the first time, nephrology practitioners across the United States could replace face-to-face visits with telemedicine for patients receiving in-center hemodialysis. This study describes patients' perspectives on the use of telemedicine during in-center hemodialysis.

STUDY DESIGN: A qualitative study.

SETTING & PARTICIPANTS: Thirty-two patients from underserved populations (older, less educated, unemployed, persons of color) receiving in-center hemodialysis who used telemedicine with their nephrologist during the COVID-19 pandemic.

ANALYTICAL APPROACH: Telephone semistructured interviews were …

Clinical Mycology Today: Emerging Challenges And Opportunities, Jessica Little, Adriana M Rauseo, Julio C Zuniga-Moya, Andrej Spec, Peter Pappas, John Perfect, Todd Mccarthy, Ilan S Schwartz

2020-Current year OA Pubs

The Mycoses Study Group Education and Research Consortium is a collective of clinicians, researchers, and educators with the common goal to advance awareness, diagnosis, and management of invasive fungal diseases. Clinical Mycology Today, the Mycoses Study Group Education and Research Consortium's biennial meeting, is dedicated to discussing the most pressing contemporary issues facing the field of clinical mycology, promoting clinical, translational, and basic science collaborations, and mentoring the next generation of clinical mycologists. Here, we review the current opportunities and challenges facing the field of mycology that arose from discussions at the 2022 meeting, with emphasis on novel host risk …

Implementation Strategies To Improve Hiv Care Cascade Outcomes In Low- And Middle-Income Countries: A Systematic Review From 2014 To 2021, Sita Lujintanon, Ingrid Eshun-Wilson, Noelle Le Tourneau, Laura Beres, Sheree Schwartz, Stefan Baral, Ryan Thompson, Ashley Underwood, Branson Fox, Elvin H Geng, Christopher G Kemp

2020-Current year OA Pubs

INTRODUCTION: In low- and middle-income countries (LMICs), which are disproportionately affected by the HIV epidemic and manage limited resources, optimized implementation strategies are needed to enhance the efficiency of the HIV response. Assessing strategy usage to date could identify research gaps and inform future implementation efforts. We conducted a systematic review to describe the features and distributions of published implementation strategies attempting to improve HIV treatment service delivery and outcomes.

METHODS: We searched PubMed, Embase, and CINAHL and screened abstracts and full texts published between 1 January 2014 and 27 August 2021, for English-language studies conducted in LMICs that described …

Diagnostic Efficacy And Clinical Impact Of Image-Guided Core Needle Biopsy Of Suspected Vertebral Osteomyelitis, Winston L Winkler, Ige A George, Sumanth Gandra, Jonathan C Baker, Anderanik Tomasian, Benjamin Northrup, Theodore L Vander Velde, Travis J Hillen, Chongliang Luo, Resten Imaoka, Gino M Dettorre, Jack W Jennings

2020-Current year OA Pubs

OBJECTIVES: The diagnostic yield and clinical impact of image-guided core needle biopsy (ICNB) of suspected vertebral osteomyelitis in adults is heterogenous in published studies owing to small sample sizes, indicating the need for large cohort studies.

METHODS: A retrospective analysis of ICNBs was performed from 2010 to 2021 for patients with imaging findings consistent with vertebral osteomyelitis. For each biopsy, a series of factors were analyzed, as well as if histopathology was diagnostic of osteomyelitis and if microbiological cultures were positive. In addition, it was recorded in what way biopsy influenced clinical management regarding antimicrobial treatment. A multivariate statistical analysis …

Pengaruh Covid-19 Terhadap Imbal Hasil Saham Perusahaan Sektor Kesehatan, Teknologi, Keuangan, Transportasi Dan Logistik Yang Terdaftar Di Bursa Efek Indonesia Periode Januari – Mei 2020, Ghina Salsabila, Eko Rizkianto

Jurnal Manajemen dan Usahawan Indonesia

This study aims to explore the impact of Covid-19 confirmed cases and Covid-19 death cases on stock return of healthcare, technology, finance, transportation, and logistic sector companies listed on Indonesia Stock Exchange in January – May 2020. Using panel data regression method, the study found that Covid-19 confirmed cases significantly affect stock return of healthcare, technology, finance, transportation, and logistic sector companies. However, there are no significant impact of Covid-19 death cases on stock return of healthcare, technology, finance, transportation, and logistic sector companies.

Detection Of Tuberculosis Using 2-D Photonic Crystal-Based Biosensor, Markov Vladimir, Skobelev Maksim, Neeraja Patil, Prathap P B, Saara K

Manipal Journal of Science and Technology

While there has been a significant increase in healthcare demands and the need for precise clinical judgment, it is important to note that the performance enhancement of photonic crystal sensors is not solely attributed to this surge in demand. Instead, photonic crystal-based biosensors have demonstrated improved performance over conventional biosensors. In this study, a 2-D photonic crystal-based biosensor with a square lattice structure, measuring 6 x 6 µm in length and width respectively, was proposed. The biosensor utilizes Titanium Dioxide (TiO2) as a sensing material, where TiO2 is employed to attract target molecules present in the sample. The proposed biosensor …

An Ecological Study Of Determinants Of The Incidence Of Tuberculosis In Malang Raya Area, Lucky Radita Alma, Vita Olivionita, Hartati Eko Wardani

Preventia: The Indonesian Journal of Public Health

The Malang Raya area (Batu City, Malang City, and Malang Regency) is one of the areas in East Java where the TB rate remains quite high. It is 3,461 cases in 2020. This study aimed to find out the correlation between coverage of healthy houses, coverage of households with healthy lifestyle, population density, air temperature, humidity, and rainfall with the incidence of tuberculosis in Malang Raya in 2021. The study used an ecological study design approach. Secondary data were collected from the Health Office and the Central Bureau of Statistics (Badan Pusat Statistika/BPS) of Malang City, Malang Regency and Batu …

Determinan Kegagalan Pengobatan Pada Pasien Tuberkulosis Sensitif Obat Dewasa Di Provinsi Jawa Tengah Tahun 2022, Elizabeth Wulandari, Sudarto Ronoatmodjo

Jurnal Epidemiologi Kesehatan Indonesia

Tuberkulosis (TB) adalah salah satu penyakit menular penyebab kematian tertinggi di dunia. Pada populasi pasien TB, terdapat banyak faktor yang dapat meningkatkan risiko kejadian yang tidak diharapkan dari pengobatan. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor-faktor yang berhubungan dengan kegagalan pengobatan pada pasien TB dewasa di Provinsi Jawa Tengah pada tahun 2022. Studi cross-sectional ini menganalisis data sekunder dari Sistem Informasi TB (SITB), menggunakan 14.542 sampel yang memenuhi kriteria inklusi dan eksklusi. Pasien TB berusia >15 tahun dan terdapat hasil pengobatan merupakan kriteria inklusi dalam penelitian ini. Kegagalan pengobatan merupakan variabel dependen dan variabel independennya adalah usia, jenis kelamin, …

Assessing The Impact Of Tuberculosis On Economic Growth In Asean Countries: A Conceptual Framework And Panel Data Analysis, Agus Fitriangga, Alex Alex

Jurnal Ekonomi Kesehatan Indonesia

Tuberculosis (TB) remains a major global health issue, particularly in Southeast Asia, where its impact extends beyond public health to affect economic performance. This study evaluates the economic implications of TB incidence on gross domestic product (GDP) growth across eight ASEAN countries from 2000 to 2020. We employed a panel data regression approach, utilizing Common Effect Model (CEM), Fixed Effects Model (FEM), and Random Effects Model (REM) to analyze the relationship between TB incidence and economic growth. The dataset included annual GDP figures, TB incidence rates, foreign direct investment (FDI), labor force size, and trade openness, sourced from international databases. …

Knowledge And Attitudes Of Food Hosters Towards Personal Hygiene And Description Of The Existence Of E. Coli And Salmonella Sp In Pesantren, Siti Muthi’Ah Azzahro, Milliyantri Elvandari, Eka Andriani

Bulletin of Culinary Art and Hospitality

Personal hygiene is a health practice carried out when processing food. Lack of implementation of personal hygiene will have an impact on a person's health, such as experiencing food poisoning. The growth of a person's personal hygiene practices can be influenced by knowledge and attitudes. This research explores the knowledge and attitudes of food handlers towards personal hygiene using qualitative and quantitative approaches. A quantitative approach was performed with a cross-sectional design and a qualitative with a descriptive design. Sampling was taken using a total sampling technique, thereby, all food handlers were sampled, resulting in 30 respondents. Data analysis was …

Impact Of Infancy Conditions On Physical Growth Of Children Under-Five, Claudia Azhari, Yeni Mahwati, Yeni Suryamah, Arfian Hikmat Ramdan

Preventia: The Indonesian Journal of Public Health

Children under five years old is the age group most vulnerable to several health problems. It is important to evaluate the impact of infancy condition on their physical growth. This research aimed to examine the impact of infancy condition on the physical growth of children under-five years old. The unmatched case-control study was conducted in Puskesmas Griya Antapani areas, Bandung from May to July, 2023. A total of 112 children aged under 5 years were included in this study (56 cases and 56 control). The analysis used multivariate logistic regression to determine adjusted odds ratios (OR). The results showed that …

Knowledge Of Tour Guides In The Sekumpul Waterfall Regarding Occupational Health And Safety, Made Adhyatma Prawira Natha Kusuma, Ni Luh Gede Aris Maytadewi, Luh Putu Wulandari Artha, Rut Wiratami

Preventia: The Indonesian Journal of Public Health

Occupational health and safety is an important thing to pay attention to in any activity, one of which is in the tourism sector. In the world of tourism, many tourism activities are offered by tourism business actors, which must pay attention to the health and safety of the tourism offered. The purpose of this study was to see the level of knowledge, attitudes, and behavior of tour guides at the Sekumpul Waterfall tour, Buleleng Regency, Bali regarding occupational health and safety. This research is a cross-sectional study using a descriptive-analytic approach with a one-group pretest-posttest research design. The sampling technique …

Immunomodulators In Leprosy: A Narrative Review, Kesya Kimberly, Siti Aisha Nabila Ferina, Prima Kartika Esti

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Current therapeutic regimen, like the multidrug therapy (MDT), are effective in treating most cases, but new cases continue to emerge in Indonesia every year. While multidrug therapy alone is adequate for treating leprosy, there is a need for adjuvant treatment options to boost the host’s immune system to prevent the worsening of leprosy and reduce the activation of M. leprae, such as immunomodulators.

Discussion: Immunomodulators are drugs that can stimulate the body’s natural and adaptive defense mechanisms, acting as either immunosuppressants or immunostimulants. To understand …

Contribution To Hair And Skin Science In Indonesia Through A Research Grant Program, Michele Verschoore, Rhadeya Setiawan, Muhammad Yulianto Listiawan, Nurtami Nurtami, Eloïse Moreau De Montcheuil

Journal of General - Procedural Dermatology and Venereology Indonesia

To foster scientific advances in basic and clinical research projects, a philanthropic "hair & skin research grant" program was launched in 2021 through a partnership between University of Indonesia, Perdoski, and L’Oreal Research and Innovation. The aim of the program is to empower Indonesian scientists to generate research data on general skin and hair issues that affect the Indonesian population. We have grouped the eight grant projects awarded between 2021 and 2022 into five main themes: skin type characterization; skin microbiota; botanical extracts; photoaging therapies; and hair loss. The various studies are evaluating potential therapies for acne, skin aging, photoaging …

Behavioural Distributions Of Macrophytes In An Oxbow Lake, Dhir Beel With Reference To Its Water Quality In Assam, India, Arup Nama Das, D. K. Sharma

Journal of Bioresource Management

An Oxbow lake, Dhir Beel, situated in Western Assam, India, stands as a habitat for a plethora of plant and animal species, nurturing a vibrant ecosystem within its freshwater environs. This study sought to address concerns surrounding pollution, encroachment, siltation, and overfishing within Dhir Beel. Over a span of three years (2016-2019), samples were meticulously collected from five distinct sites to analyze both water quality and macrophyte populations. Employing the APHA method, the physico-chemical parameters of the water were evaluated, while a comprehensive identification process was undertaken to categorize the macrophytes. These aquatic plants, spanning dicots, monocots, and pteridophytes, were …

Trypanosomiasis And Its Diagnostic Techniques In Camel: A Comprehensive Review, Muhammad Aqeel, Amjad Hussain Mirani, Parvez Ahmed Khoso, Jam Kashif Sahito, Abdul Latif Bhutto, Riaz Ahmed Leghari, Muhammad Mohsen Rahimoon, Nuzhat Parveen Junejo

Journal of Bioresource Management

Trypanosomiasis, a parasitic disease caused by protozoan parasites of the genus Trypanosoma, poses a significant threat to camel populations worldwide. This study designed for the diagnostic techniques used for detecting Trypanosoma infections specifically in camels. The disease, commonly known as camel trypanosomiasis or surra, adversely impacts the health and productivity of camels, thereby affecting livelihoods dependent on these animals. Various diagnostic methods are employed for the detection of Trypanosoma infection in camels, including microscopic examination of blood smears, serological tests like ELISA (Enzyme-Linked Immunosorbent Assay), and molecular techniques such as PCR (Polymerase Chain Reaction). Each method has its strengths and …

Hubungan Campak Dengan Berat Badan Kurang Pada Anak Usia 24-59 Bulan Di Indonesia (Analisis Data Survei Status Gizi Indonesia 2021), Wiandhari Esa Gautami, Mondastri Korib Sudaryo

Jurnal Epidemiologi Kesehatan Indonesia

Berat badan kurang atau underweight merupakan masalah gizi kurang yang diukur dengan perbandingan berat badan dan umur. Berat badan kurang pada balita akan mempengaruhi pertumbuhan fisik, kemampuan kognitif, meningkatkan risiko kematian dan penularan infeksi penyakit, salah satu penyakit infeksi yang umum terjadi pada balita adalah campak. Tujuan penelitian ini adalah mengetahui hubungan infeksi campak dengan berat badan kurang pada balita usia 24-59 bulan di Indonesia, dengan mengontrol variabel kovariat diantaranya jenis kelamin, usia, pendidikan ibu BBLR, riwayat TB paru, riwayat diare, riwayat ISPA, riwayat imunisasi campak dan pola makan. Studi ini menggunakan data Survei Status Gizi Indonesia (SSGI) di 34 …

The Behavioral Contagion Effect Of Tourists’ Risk Decision-Making, Jiangchi Zhang, Chaowu Xie, Feifei Lai, Songshan Huang

Research outputs 2022 to 2026

This study investigated the contagion effect of other tourists' risk-seeking behavior on tourists' risk decision-making. It further examined the mediation of two contrasting motivational systems (approach-avoidance), and the moderation of destination management deterrence. Four experiments were conducted focusing on the risk decision-making of tourists in the context of undeveloped natural areas and tidal-bore watching settings. Independent samples t-tests, regression, and multivariate analysis of covariance were utilized to examine the proposed conceptual model. The results of Experiment 1 (n = 226) demonstrated that seeing other tourists' risk-seeking behavior had a contagion effect on tourists' risk decisions; specifically, other tourists' risk-seeking behavior …

أثر منحنيات التعلم في تقليص فترة علاج كوفيد-19 وتخفيض التكاليف المباشرة لعلاجه دراسة ميدانية: مستشفى ابن الخطيب, مخلد فؤاد شجاع

Muthanna Journal of Administrative and Economics Sciences

هدف البحث الى بيان أثر منحنيات التعلم في تقليص فترة علاج كوفيد-19 وتخفيض تكاليف المباشرة من علاجه، ومنحنيات التعلم؛ واحدة من وظائف التكلفة غير الخطية، كونه عبارة عن دالة تقيس كيفية تخفيض ساعات العمل المطلوبة لإنجاز الوحدة المنتجة من خلال تراكم خبرة العاملين وتحسين أدائهم، إذ تعتمد منحنيات التعلم على فكرة مؤداها أن أداء أي عمل بشكل متكرر يؤدي الى اكتساب خبرة وهو الأمر الذي يؤدي الى تخفيض الوقت اللازم لإنجاز الوحدة المنتجة كلما استمر العمل، وقد توصل البحث الى مجموعة من الاستنتاجات كان أهمها؛ يمكن استخدام منحنيات التعلم لتقليل تكاليف علاج كوفيد-19 وتحسين الكفاءة الإنتاجية للعامين في المستشفيات من …

Severe Febrile Neutropenia And Pancytopenia In A Patient With Advanced Hepatocellular Carcinoma Treated With Atezolizumab And Bevacizumab: A Case Report, Shadi Chamseddine, Michael Lapelusa, Kristen Carter, Van Nguyen, Yehia I Mohamed, Yara Sakr, Cristhiam M Rojas-Hernandez, Rikita I Hatia, Manal Hassan, John A Goss, Khaled M Elsayes, Asif Rashid, Ryan Sun, Hop Sanderson Tran Cao, Hesham M Amin, Ahmed O Kaseb

Faculty, Staff and Student Publications

BACKGROUND: Immune checkpoint inhibitors (ICIs), agents that stimulate T-cell function, have become the standard first-line treatment for unresectable hepatocellular carcinoma (HCC). However, they may also cause immune-related adverse events (irAEs), which are rare and have not been extensively reported. Here, we describe a case of severe febrile neutropenia and pancytopenia after atezolizumab plus bevacizumab (atezo/bev) therapy and its treatment course.

CASE DESCRIPTION: The combination of atezo/bev was initiated as the first-line treatment for a man in his early 50s, who was diagnosed with unresectable HCC. The first treatment cycle was administered in the outpatient setting, and the patient developed a …

Problems Scanning Related To Stunting Using Iceberg Theory Model In Salakbrojo Village Central Java, Yuniarti Yuniarti, Ristiawati Ristiawati, Dewi Nugraheni Restu Mastuti, Muhammad Fatih

Media Kesehatan Masyarakat Indonesia

The prevalence of stunting to date is 21,6%, which is far from target which is 14%. Research aimed to elaborate on problem of stunting using iceberg method model analysis. The research is a qualitative study with a phenomenological approach to obtain idea of stunting occurrence pattern as well as the root of problem. Data was collected by assigning focused group discussion. Correspondents were ten mothers of toddlers, five health cadres, a secretary of rural, and a rural midwife. Validity test was done by doing data source triangulation during focused group discussions. Mental model analysis was taken using directly elicited mental …

Factors Affecting The Success Of Exclusive Breastfeeding Among Mothers Recovered From Covid-19, Ulfatul Latifah, Nora Rahmanindar, Ardhi Henda Karmandika

Media Kesehatan Masyarakat Indonesia

Exclusive breastfeeding for the first 6 months and continued breastfeeding with complementary foods up to 2 years are emphasized by the World Health Organization. Amid the COVID-19 pandemic, maternal concerns about virus transmission through breastfeeding have surfaced. Despite these concerns, breastfeeding remains the primary recommendation due to its manifold health benefits. This research, conducted in Tegal City's Margadana sub-district, investigates factors influencing exclusive breastfeeding success among mothers recovered from COVID-19. Using an analytical observational design with a cross-sectional approach, the study explores the link between COVID-19 symptoms in infants and exclusive breastfeeding success, revealing a significant correlation (p-value=0.042). Conversely, breast …