Digital Commons Network^™

Immunohistochemical Expression Of Estrogen Receptor In Papillary Thyroid Carcinoma With Lymph Node Metastasis, Furqan J. Albderi, Kaswer M. Altoriahi

Iraqi Postgraduate Medical Journal

Background: Papillary thyroid carcinoma (PTC) is the most common well-differentiated thyroid malignancy. The female predominance of PTC suggests a potential role for estrogen signaling, mediated through estrogen receptors (ER), in thyroid carcinogenesis and progression.Objective: This study aimed to evaluate estrogen receptor protein expression in papillary thyroid carcinoma with lymph node metastasis and to analyze its association with clinicopathological parameters.Methods: A retrospective study was conducted on 50 formalin-fixed, paraffin-embedded thyroid and corresponding lymph node tissue specimens from Iraqi patients with PTC and lymph node metastasis. ER expression was assessed by immunohistochemistry. Associations between ER expression and clinicopathological variables were analyzed using …

Family Medicine In Iraq: Bridging The Gap Between Training And Practice For Health System Reform, Eman A. Al-Kaseer

Iraqi Postgraduate Medical Journal

No abstract provided.

Evaluating The Usefulness Of 24-Hour Video Eeg Monitoring In Dr. Sa’Ad Alwitry’S Hospital, Baghdad, Iraq, Ebtehal Dhiyaa, Akram Mohammad Al-Mahdawi, Muataz Fairooz Abd

Iraqi Postgraduate Medical Journal

Background: Video electroencephalography (VEEG) monitoring, which combines EEG with synchronized video recording, is a valuable but resource-intensive tool for evaluating seizure disorders. While its role in diagnosis and classification is established, its specific impact on altering provisional diagnoses and guiding treatment remains underexplored.Objective: To assess the diagnostic utility of 24-hour inpatient VEEG monitoring in confirming or modifying provisional diagnoses and reducing misdiagnosis in patients with paroxysmal events.Methods: A retrospective analysis was conducted on 192 patients who underwent VEEG monitoring at Dr. Saad Alwitry Hospital between January and December 2018. Patient records were reviewed to assess the impact of VEEG on …

Esophageal Stricture Post Congenital Tracheoesophageal Fistula Repair, Zaid A. Zaid, Momtaz Al-Nima

Iraqi Postgraduate Medical Journal

Background: It’s a narrowing of > 50% of the esophagus lumen or as a narrowing detected on a contrast study , or at esophagostomy in combination with symptomsTracheoesophageal fistula (TEF) is a relatively rare congenital anomaly occurring in one in 2500-3000 live births (3)Moreover, the life expectancy of the patients without proper treatment may be measured in weeksAim of study: evaluation of the demographics, surgical details, and postoperative outcomes of pediatric patients undergoing surgery for Tracheoesophageal Fistula (TEF) repair.Methods: The study was conducted at Pediatric Teaching Hospital/Medical City from December, 2022, to November , 2023. A total of 35 cases post …

Evaluation Of Peripheral Nerves In Patients With Acromegaly By Electrodiagnostic Study, Taiseer Saad Musa, Farqad Bader Hamdan, Abbas Mahdi Rahmah

Iraqi Postgraduate Medical Journal

Background: Acromegaly is a rare multisystem disorder caused by excess growth hormone (GH) and insulin-like growth factor 1 (IGF-1), typically from a pituitary somatotroph adenoma. Neurological complications, particularly peripheral neuropathies, are common but under-investigated.Objectives: To evaluate peripheral nerve involvement in Iraqi patients with acromegaly and assess the impact of IGF-1 levels, disease duration, adenoma size, and other clinical variables on nerve function.Methods: A cross-sectional study included 41 acromegalic patients (≥25 years) who underwent detailed neurophysiological testing. Patients were classified as metabolically controlled or uncontrolled based on IGF-1 levels.Results: IGF-1 and GH levels were significantly lower in the controlled group (p<0.001), while other clinical variables showed no significant differences. Neurophysiological findings revealed significantly reduced sensory and motor amplitudes, prolonged latencies, and slower conduction velocities in the uncontrolled group. IGF-1 levels correlated positively with sensory and motor latencies and negatively with conduction velocities and CMAP amplitudes. Larger adenoma size and presence of diabetes were also associated with worse nerve parameters. Deep X-ray therapy and surgical excision showed beneficial associations with median nerve conduction velocity.Conclusion: Peripheral nerve dysfunction, including carpal tunnel syndrome and polyneuropathy, is more severe in metabolically uncontrolled acromegaly. Macroadenomas and poor biochemical control are linked with worse neurophysiological outcomes.

Congenital Heart Disease In Infants Of Diabetic Mothers (Pediatrics Hospital Based Study), Esraa Ali Mathboob Mahdi, Basil M. Hanudi

Iraqi Postgraduate Medical Journal

Background: Infants born to diabetic mothers are at elevated risk for neonatal complications, including metabolic, hematologic, respiratory, cardiac, and neurological disorders. Notably, insulin-dependent diabetes increases the likelihood of congenital heart diseases (CHDs). Aim: This study aimed to determine the incidence and associated factors of cardiac complications among neonates born to diabetic mothers and to identify the prevalent patterns of congenital heart defects in this population. Methods: An analytical cross-sectional study was conducted over a 10-month period (July 1, 2020 to April 30, 2021) at the Neonatal Care Unit of Child’s Central Teaching Hospital. The study included 100 neonates admitted within …

Examining Data Richness In Undergraduate Students’ Reflections: A Linguistic Analysis Of Three Data Collection Methods, Kirsten A. Davis, Anne Wrobetz

School of Engineering Education Faculty Publications

Researchers select data collection methods for a variety of reasons. In our research on experiential education programs, we perceived that when we collected students’ reflections using different methods, the data we received was different. However, we found few existing studies to help us characterize what was different across our data sets to inform our decisions about which methods to use. Thus, the purpose of our study was to compare data richness across three data sets from previous studies of engineering students studying abroad, each collected using a different method (written diaries, interviews, video diaries). We used linguistic inquiry as a …

Thromboelastography-Guided Laparoscopic Splenectomy In A Patient With Immune Thrombocytopenia And Recent Drug-Eluting Stent Placement: A Case Report, Josue Gaona, Janki Patel

School of Medicine Student Publications and Presentations

Background

Perioperative management of patients with immune thrombocytopenia (ITP) is particularly challenging when complicated by recent coronary stenting requiring dual antiplatelet therapy (DAPT), due to competing risks of bleeding and thrombosis.

Case Presentation

We report the case of an 80-year-old male with refractory ITP and recent drug-eluting stent placement who underwent elective laparoscopic splenectomy. Although preoperative optimization with corticosteroids and intravenous immunoglobulin increased platelet count from <  20 × 109/L to 177 × 109/L, functional hemostatic adequacy remained uncertain given concurrent ITP and ongoing antiplatelet therapy. Thromboelastography (TEG) was performed using the TEG 6s system with a Global Hemostasis Cartridge. Standard TEG parameters demonstrated preserved clot initiation, formation, and strength across multiple channels, supporting progression to surgery. Laparoscopic splenectomy was completed under general anesthesia without complications or need for transfusion. The patient recovered on the general surgical ward and was discharged on Postoperative Day 3 with a platelet count of 139 × 109/L. Platelet count 2 weeks postoperatively was 343 × 109/L.

Conclusion

This case highlights the utility of TEG as a tool to guide perioperative decision-making in patients with ITP receiving antiplatelet therapy. By providing a functional assessment of coagulation, TEG can help individualize perioperative …

Ai-Powered Synthetic Biology: Current Situation, Challenges, And Future Perspectives, Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli

Research Outputs: 2025-Present

Synthetic biology has evolved from a set of engineering aspirations to an operationally sophisticated discipline, and artificial intelligence (AI) is its fastest-growing accelerant. This review traces that convergence across six interlocking domains: systems-level biological modeling, de novo protein engineering, metabolic and microbial programming, multi-omics data integration, regulatory element design, and clinical translation. For each domain, we survey established results, integrate findings from 2010–2026 literature, and articulate the trajectories that will define the next decade. Emerging themes include physics-informed neural networks for mechanistically constrained biological modeling, drug design, and federated learning architectures that allow global omics collaboration without centralizing sensitive data, …

Environmental Impact Of Preventative Fire-Retardant Products On Soil Chemistry, Elisabeth Kraycik

Master's Theses

Human-caused ignitions account for most wildfires in the United States, particularly along roadsides, utility corridors, and other high-risk infrastructure where fine fuels are abundant and ignition sources are concentrated. These settings are often embedded within grassland and shrubland ecosystems, where fires spread rapidly and can threaten nearby communities and assets. Preventative fire-retardant products (PFRPs) have emerged as a promising strategy for reducing ignition likelihood in these environments. Unlike traditional aerial retardants applied during active suppression, PFRPs are designed for annual, pre-season application to ignition-prone locations. Despite their growing use, the environmental consequences of repeated PFRP applications remain poorly understood, especially …

System Integration And Validation Of The Cal Poly Spacecraft Attitude Dynamics Simulator Mk. Iv, Bricen S. Rigby

Master's Theses

The Cal Poly Spacecraft Attitude Dynamics Simulator (SADS) is an ongoing project that seeks to enable the simulation and validation of sensors, actuators, and control logic related to spacecraft attitude control. The SADS platform rests atop a spher- ical air-bearing device which allows for nearly frictionless rotation in all three axes. The orientation of the platform is controlled by four reaction wheels arranged in a pyramidal configuration. Over the past few years, there have been significant updates to the reaction wheel subsystem, as well as requests for a more capable central com- puter. Therefore, a new system architecture for the …

2026 Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Feasibility Of Using Electronic Medical Records To Identify Postdischarge Mental Health Screening Documentation In Trauma Patients., Kellie Girardot, Julie L Otte

Emergency Medicine and Trauma

BACKGROUND: Injury leads to long-term physical and mental health challenges, yet inpatient screening for post-traumatic stress disorder and depression remains inconsistent, and postdischarge mental health is poorly understood, particularly in less resourced trauma centers where emerging symptoms may go unrecognized.

OBJECTIVE: To evaluate the feasibility of using the electronic medical record to identify postdischarge mental health screening documentation in adult trauma patients within 6 months after discharge.

METHODS: This retrospective descriptive feasibility study was conducted at a midwestern US regional Level II trauma center serving a predominantly rural catchment area. Adult trauma patients admitted between January 1 and December 31, …

Irene Calboli, Irene Calboli

Faculty CVs

No abstract provided.

Terri L. Helge, Terri Lynn Helge

Faculty CVs

No abstract provided.

Aric K. Short, Aric K. Short

Faculty CVs

No abstract provided.

Nh Ece Research Consortium State Government Stakeholder Map, Jess Carson, Evan England, Briana Ermanni

New Hampshire Early Care and Education Research Consortium

New Hampshire's early care and education (ECE) ecosystem is complex and includes a broad, dynamic community of people and organizations who contribute to and rely upon ECE research. This visual stakeholder "map" documents the areas of state government that support the NH ECE field. These maps rely on contributions, updates, and refinements from the field and are meant to be a shared resource reflecting the complexity of partnerships in NH's ECE ecosystem.

The Accidental Entrepreneur: How Military Spouses Take Their Careers Into Their Own Hands, Jennifer Barnhill, Rosalinda Maury, Jeanette Harvie

Institute for Veterans and Military Families

The Accidental Entrepreneur is the second narrative profile in the Reimagining Military Spouse Employment series, a companion to the initiative's data briefs. Through the story of a mid-career military spouse who builds a business after repeated career disruptions, it examines why many spouses turn to entrepreneurship and what stands in their way. The profile covers the barriers spouses face when starting a business, including access to funding, certifications, and grants, along with the reality that self-employment does not eliminate the military spouse earnings penalty. It offers guidance for military spouses considering entrepreneurship and for the community leaders positioned to support …

Colonial Futures: Ngaio Marsh, War, And The End Of Empire, Heather M. Robinson

Publications and Research

Between the years of 1941 and 1945, Ngaio Marsh published three New Zealand-focused whodunnits; all three of these stories explore the impacts of the Second World War to some degree. What is curious is not that Marsh wrote about the war, but her sustained focus on New Zealand and New Zealanders, given that Marsh’s fiction usually took place in London or its surrounding counties. It marks the impact on Marsh of the global conflict that was changing the world, and shaking the foundations of colonialism and modernity as they had been known before 1939. In this essay, I explore how …

Vehicle Autonomy To Ecosystem Intelligence: A Systematic Review Of Dynamic Vision Architectures In Surface Mining Operations, Nana Yaa Damtewaa Anti, Samuel Frimpong, Muhammad Azeem Raza

Mining Engineering Faculty Research & Creative Works

Autonomous Haulage Systems (AHS) have significantly transformed surface mining operations by improving safety, productivity, and operational consistency. Currently, AHS predominantly rely on vehicle-centric perception architectures. Onboard LiDAR, radar, cameras, and Global Navigation Satellite Systems (GNSS) perform sensing, interpretation, and decision-making within individual systems. These processes enable collision avoidance and path tracking. However, they are limited in their ability to consider the broader, dynamic mining environment characterized by dust, terrain degradation, geotechnical instability, heterogeneous traffic, and rapidly evolving operational conditions. This paper presents a systematic review of dynamic vision systems of AHS in surface mining. It critically analyzes the transition from …

A System Dynamics Model For Analyzing Customer Satisfaction Drivers In A Manufacturing Context, Mahnaz Asgari Sooran, Venkat Allada, Adewole Adegbola

Engineering Management and Systems Engineering Faculty Research & Creative Works

Customer satisfaction offers economic benefits and competitive advantage to manufacturing enterprises. However, a gap exists in understanding how to achieve customer satisfaction due to the complexities involved in coordinating various subsystems of an enterprise in an efficient manner. In this paper, we identified four internal and external-to-the-firm customer satisfaction drivers which include: government policies, supply chain reliability, knowledge management, and manufacturing performance criteria such as on-time delivery, quality and cost. We then developed a conceptual framework to define the non-linear mathematical relationships between drivers using system dynamics modeling. We conducted "what-if "scenario analyses for a base case, optimistic case and …

Thiol-Based Neuroprotective Copolymers Acutely Restore Redox Metabolism And Mediate Vasogenic Edema In A Mouse Model Of Traumatic Brain Injury, Evan T. Curtis, Brandon Z. Mcdonald, Aria W. Tarudji, Aaron M. Priester, Anthony J. Convertine, Forrest M. Kievit

Materials Science and Engineering Faculty Research & Creative Works

Effective pharmaceutical interventions for treating the secondary damage associated with traumatic brain injury (TBI) are limited due to poor delivery into the brain, insufficient target engagement, and an incomplete understanding of the pathophysiological changes that occur post-impact. Thus, nanoparticles (NP), which have an enhanced permeation and retention-like effect within the perturbed blood-brain barrier, have grown as a potential candidate for treating TBI. We have investigated the antioxidant capacity of thiol-based NP, termed neuroprotective copolymers (NPC3), and their ability to neutralize reactive oxygen species (ROS) and lipid peroxidation products (LPOx). Here, we assessed the efficacy of NPC3 for alleviating the secondary …

An Orally Available Pfpkg Inhibitor Blocks Plasmodium's Infection Of The Liver, Hanna Dhiyebi, Aminata Mbaye, Anusha Thaniana, John Gilleran, Tyler Eck, Kutub Ashraf, Karl Kudyba, Howard Fan, Steve Seibold, Kevin P. Battaile, John Siekierka, Evan Johnson, Alison Roth, Amy De Rocher, Scott Lovell, Edward B. Miller, Jacques Y. Roberge, Purnima Bhanot

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

Malaria remains a global health threat exacerbated by emerging resistance to antimalarial therapies and insecticides, climate-driven outbreaks, and limited chemoprotective options. Here, we report the characterization of RUPB-61, the first orally bioavailable inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG). RUPB-61 prevents infection by P. falciparum and P. cynomolgi sporozoites, including the formation of hypnozoites by the latter. A single oral dose blocks liver infection by P. berghei sporozoites in vivo, demonstrating efficacy consistent with further development as a once-weekly prophylaxis based on pharmacokinetic modeling. The compound retains activity against field isolates resistant to chloroquine, mefloquine, cycloguanil, sulfadoxine and pyrimethamine, …

J Mich Dent Assoc July 2026

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200-plus members. It remains the main publication reaching Michigan dentists and is available worldwide through ADA Commons.

The July 2026 (Volume 108, No. 7) issue of the Journal is published in print format to provide updates and insights for Michigan's oral health community and MDA members. Print editions occur every other month beginning with January.

The July 2026 issue of the Journal of the Michigan Dental Association celebrates the 40th anniversary of the association's …

Research Nexus : Volume 39 – 2026, Office Of Research And Graduate Studies

Office of Research and Graduate Studies Archives

• Researcher Spotlight
• Research Milestones & News
• Capacity Building Initiatives
• Celebrating New Beginnings
• NIH Updates & Other Resources
• Explore New Grant Opportunities

Persistent Gaps In Management And Risk Factor Control Among Patients With Atherosclerotic Cardiovascular Disease: All Of Us Research Program, Yakubu Bene-Alhasan, Soad Al Osta, Yussif Issaka, Isaac Acquah, Ahmad Alkhatib, Leen Othman, Samuel Mensah, Ato Howard, Christie Ballantyne, Salim S. Virani

Population Health, East Africa

Background

Methods

Deepfakes As Crisis Triggers: Experimental Evidence On Response Strategy Effectiveness, Responsibility Attributions, And Sharing Intentions, Alicia Mason, Mariah Laman, Tanner Glenn, Treyton Meyers

Faculty Submissions

The term deepfake refers to falsified media content created using artificial intelligence (AI) technologies to manipulate audio, video, or images. Deepfake news fabrications are designed to appear highly realistic, making it difficult for audiences to distinguish them from authentic content. Responding to deepfake-induced  reputational threats therefore presents a unique challenge for organizations. Despite the growing prevalence of deepfake technology, little experimental research has examined how different crisis communication strategies perform in mitigating the reputational and relational harm posed by deepfake-induced crises. Accordingly, this study seeks to (1) examine how exposure to deepfake news relates to public perceptions and affect toward …

Development And Implementation Of Educational Modules On Management Of Neonates With Critical Congenital Heart Disease In The Delivery Room (Learn-Chd)., Noorjahan Ali, Brenda Law, Alyssa R. Thomas, Philip T. Levy, Ruby Gupta, Summer Elshenawy, Danielle Reed, Leeann R. Pavlek, Jennifer Shepherd, Sharada H. Gowda, Molly K. Ball, Beth Ann Johnson, Chloe Joynt

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Neonates with congenital heart disease may require delivery room interventions beyond standard care. Because existing guidelines and educational programs rarely address these needs, we developed and evaluated targeted educational modules.

METHODS: Teams were randomized to online eLearning modules or directed readings. Individual pre-/post-knowledge scores were compared. Team performance was tested in simulated delivery scenarios including abruption, hypoplastic left heart syndrome, d-transposition of great arteries and congenital complete heart block.

RESULTS: 32 teams from 9 centers participated. The module group had improved knowledge scores (mean change 6% vs -0.3% e-Learning group, p = 0.01). Simulation performance was similar between groups …

Immediate Postoperative Pacing Dependency Is Not Associated With Worse Mid-Term Survival In Redo Mitral Valve Surgery, Devon Kelley, Joyce Ho, Andrew Belec, Takahiro Tashima, Victoria Li, James Lao, Varun Kathawate, Kazuhiro Ueno, Amit Iyengar, Jessica Dominic, Pavan Atluri

Division of Cardiology Faculty Papers

Risk factors (RF) for permanent pacemaker (PPM) placement in cardiac surgery include valvular operations and redo operations. We aim to identify RF for PPM placement prior to discharge (DC) specifically among redo mitral valvular operations, and to analyze outcomes in this population. Our retrospective review considered 943 patients undergoing redo MV operations between 01/2002 and 12/2021, excluding patients experiencing in-hospital death within 48 hours of their operation and patients with existing PPM or implanted cardiac defibrillator (ICD). Patients (n = 742) were categorized based on whether they received a PPM before DC or not. Of the 742 patients analyzed, 47 …

Learning Across Borders Through Outbreak Investigation: A Mixed-Methods Evaluation Of An International Collaborative Workshop For Medical Students, Maysa Falah, Michael Dillon, Delphine Kayem, James Edwards, Jonah Fox, Latifa Adarmouch

Faculty of Health Datasets

Public Data set