Digital Commons Network^™

Ai-Powered Synthetic Biology: Current Situation, Challenges, And Future Perspectives, Izem Olcay Sahin, Nuriye Gokce, Duygu T. Yildirim, A. Baki Yildirim, Hilal Akalın, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert S. Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Kosi Gramatikoff, Ed Judge, Milica Markovic, Radka Kaneva, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Chiara Coppola, Matteo Bertelli

Research Outputs: 2025-Present

Synthetic biology has evolved from a set of engineering aspirations to an operationally sophisticated discipline, and artificial intelligence (AI) is its fastest-growing accelerant. This review traces that convergence across six interlocking domains: systems-level biological modeling, de novo protein engineering, metabolic and microbial programming, multi-omics data integration, regulatory element design, and clinical translation. For each domain, we survey established results, integrate findings from 2010–2026 literature, and articulate the trajectories that will define the next decade. Emerging themes include physics-informed neural networks for mechanistically constrained biological modeling, drug design, and federated learning architectures that allow global omics collaboration without centralizing sensitive data, …

Environmental Impact Of Preventative Fire-Retardant Products On Soil Chemistry, Elisabeth Kraycik

Master's Theses

Human-caused ignitions account for most wildfires in the United States, particularly along roadsides, utility corridors, and other high-risk infrastructure where fine fuels are abundant and ignition sources are concentrated. These settings are often embedded within grassland and shrubland ecosystems, where fires spread rapidly and can threaten nearby communities and assets. Preventative fire-retardant products (PFRPs) have emerged as a promising strategy for reducing ignition likelihood in these environments. Unlike traditional aerial retardants applied during active suppression, PFRPs are designed for annual, pre-season application to ignition-prone locations. Despite their growing use, the environmental consequences of repeated PFRP applications remain poorly understood, especially …

System Integration And Validation Of The Cal Poly Spacecraft Attitude Dynamics Simulator Mk. Iv, Bricen S. Rigby

Master's Theses

The Cal Poly Spacecraft Attitude Dynamics Simulator (SADS) is an ongoing project that seeks to enable the simulation and validation of sensors, actuators, and control logic related to spacecraft attitude control. The SADS platform rests atop a spher- ical air-bearing device which allows for nearly frictionless rotation in all three axes. The orientation of the platform is controlled by four reaction wheels arranged in a pyramidal configuration. Over the past few years, there have been significant updates to the reaction wheel subsystem, as well as requests for a more capable central com- puter. Therefore, a new system architecture for the …

2026 Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Feasibility Of Using Electronic Medical Records To Identify Postdischarge Mental Health Screening Documentation In Trauma Patients., Kellie Girardot, Julie L Otte

Emergency Medicine and Trauma

BACKGROUND: Injury leads to long-term physical and mental health challenges, yet inpatient screening for post-traumatic stress disorder and depression remains inconsistent, and postdischarge mental health is poorly understood, particularly in less resourced trauma centers where emerging symptoms may go unrecognized.

OBJECTIVE: To evaluate the feasibility of using the electronic medical record to identify postdischarge mental health screening documentation in adult trauma patients within 6 months after discharge.

METHODS: This retrospective descriptive feasibility study was conducted at a midwestern US regional Level II trauma center serving a predominantly rural catchment area. Adult trauma patients admitted between January 1 and December 31, …

Irene Calboli, Irene Calboli

Faculty CVs

No abstract provided.

Terri L. Helge, Terri Lynn Helge

Faculty CVs

No abstract provided.

Aric K. Short, Aric K. Short

Faculty CVs

No abstract provided.

Nh Ece Research Consortium State Government Stakeholder Map, Jess Carson, Evan England, Briana Ermanni

New Hampshire Early Care and Education Research Consortium

New Hampshire's early care and education (ECE) ecosystem is complex and includes a broad, dynamic community of people and organizations who contribute to and rely upon ECE research. This visual stakeholder "map" documents the areas of state government that support the NH ECE field. These maps rely on contributions, updates, and refinements from the field and are meant to be a shared resource reflecting the complexity of partnerships in NH's ECE ecosystem.

The Accidental Entrepreneur: How Military Spouses Take Their Careers Into Their Own Hands, Jennifer Barnhill, Rosalinda Maury, Jeanette Harvie

Institute for Veterans and Military Families

The Accidental Entrepreneur is the second narrative profile in the Reimagining Military Spouse Employment series, a companion to the initiative's data briefs. Through the story of a mid-career military spouse who builds a business after repeated career disruptions, it examines why many spouses turn to entrepreneurship and what stands in their way. The profile covers the barriers spouses face when starting a business, including access to funding, certifications, and grants, along with the reality that self-employment does not eliminate the military spouse earnings penalty. It offers guidance for military spouses considering entrepreneurship and for the community leaders positioned to support …

Colonial Futures: Ngaio Marsh, War, And The End Of Empire, Heather M. Robinson

Publications and Research

Between the years of 1941 and 1945, Ngaio Marsh published three New Zealand-focused whodunnits; all three of these stories explore the impacts of the Second World War to some degree. What is curious is not that Marsh wrote about the war, but her sustained focus on New Zealand and New Zealanders, given that Marsh’s fiction usually took place in London or its surrounding counties. It marks the impact on Marsh of the global conflict that was changing the world, and shaking the foundations of colonialism and modernity as they had been known before 1939. In this essay, I explore how …

Vehicle Autonomy To Ecosystem Intelligence: A Systematic Review Of Dynamic Vision Architectures In Surface Mining Operations, Nana Yaa Damtewaa Anti, Samuel Frimpong, Muhammad Azeem Raza

Mining Engineering Faculty Research & Creative Works

Autonomous Haulage Systems (AHS) have significantly transformed surface mining operations by improving safety, productivity, and operational consistency. Currently, AHS predominantly rely on vehicle-centric perception architectures. Onboard LiDAR, radar, cameras, and Global Navigation Satellite Systems (GNSS) perform sensing, interpretation, and decision-making within individual systems. These processes enable collision avoidance and path tracking. However, they are limited in their ability to consider the broader, dynamic mining environment characterized by dust, terrain degradation, geotechnical instability, heterogeneous traffic, and rapidly evolving operational conditions. This paper presents a systematic review of dynamic vision systems of AHS in surface mining. It critically analyzes the transition from …

A System Dynamics Model For Analyzing Customer Satisfaction Drivers In A Manufacturing Context, Mahnaz Asgari Sooran, Venkat Allada, Adewole Adegbola

Engineering Management and Systems Engineering Faculty Research & Creative Works

Customer satisfaction offers economic benefits and competitive advantage to manufacturing enterprises. However, a gap exists in understanding how to achieve customer satisfaction due to the complexities involved in coordinating various subsystems of an enterprise in an efficient manner. In this paper, we identified four internal and external-to-the-firm customer satisfaction drivers which include: government policies, supply chain reliability, knowledge management, and manufacturing performance criteria such as on-time delivery, quality and cost. We then developed a conceptual framework to define the non-linear mathematical relationships between drivers using system dynamics modeling. We conducted "what-if "scenario analyses for a base case, optimistic case and …

Thiol-Based Neuroprotective Copolymers Acutely Restore Redox Metabolism And Mediate Vasogenic Edema In A Mouse Model Of Traumatic Brain Injury, Evan T. Curtis, Brandon Z. Mcdonald, Aria W. Tarudji, Aaron M. Priester, Anthony J. Convertine, Forrest M. Kievit

Materials Science and Engineering Faculty Research & Creative Works

Effective pharmaceutical interventions for treating the secondary damage associated with traumatic brain injury (TBI) are limited due to poor delivery into the brain, insufficient target engagement, and an incomplete understanding of the pathophysiological changes that occur post-impact. Thus, nanoparticles (NP), which have an enhanced permeation and retention-like effect within the perturbed blood-brain barrier, have grown as a potential candidate for treating TBI. We have investigated the antioxidant capacity of thiol-based NP, termed neuroprotective copolymers (NPC3), and their ability to neutralize reactive oxygen species (ROS) and lipid peroxidation products (LPOx). Here, we assessed the efficacy of NPC3 for alleviating the secondary …

An Orally Available Pfpkg Inhibitor Blocks Plasmodium's Infection Of The Liver, Hanna Dhiyebi, Aminata Mbaye, Anusha Thaniana, John Gilleran, Tyler Eck, Kutub Ashraf, Karl Kudyba, Howard Fan, Steve Seibold, Kevin P. Battaile, John Siekierka, Evan Johnson, Alison Roth, Amy De Rocher, Scott Lovell, Edward B. Miller, Jacques Y. Roberge, Purnima Bhanot

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

Malaria remains a global health threat exacerbated by emerging resistance to antimalarial therapies and insecticides, climate-driven outbreaks, and limited chemoprotective options. Here, we report the characterization of RUPB-61, the first orally bioavailable inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG). RUPB-61 prevents infection by P. falciparum and P. cynomolgi sporozoites, including the formation of hypnozoites by the latter. A single oral dose blocks liver infection by P. berghei sporozoites in vivo, demonstrating efficacy consistent with further development as a once-weekly prophylaxis based on pharmacokinetic modeling. The compound retains activity against field isolates resistant to chloroquine, mefloquine, cycloguanil, sulfadoxine and pyrimethamine, …

J Mich Dent Assoc July 2026

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200-plus members. It remains the main publication reaching Michigan dentists and is available worldwide through ADA Commons.

The July 2026 (Volume 108, No. 7) issue of the Journal is published in print format to provide updates and insights for Michigan's oral health community and MDA members. Print editions occur every other month beginning with January.

The July 2026 issue of the Journal of the Michigan Dental Association celebrates the 40th anniversary of the association's …

Research Nexus : Volume 39 – 2026, Office Of Research And Graduate Studies

Office of Research and Graduate Studies Archives

• Researcher Spotlight
• Research Milestones & News
• Capacity Building Initiatives
• Celebrating New Beginnings
• NIH Updates & Other Resources
• Explore New Grant Opportunities

Persistent Gaps In Management And Risk Factor Control Among Patients With Atherosclerotic Cardiovascular Disease: All Of Us Research Program, Yakubu Bene-Alhasan, Soad Al Osta, Yussif Issaka, Isaac Acquah, Ahmad Alkhatib, Leen Othman, Samuel Mensah, Ato Howard, Christie Ballantyne, Salim S. Virani

Population Health, East Africa

Background

Methods

Deepfakes As Crisis Triggers: Experimental Evidence On Response Strategy Effectiveness, Responsibility Attributions, And Sharing Intentions, Alicia Mason, Mariah Laman, Tanner Glenn, Treyton Meyers

Faculty Submissions

The term deepfake refers to falsified media content created using artificial intelligence (AI) technologies to manipulate audio, video, or images. Deepfake news fabrications are designed to appear highly realistic, making it difficult for audiences to distinguish them from authentic content. Responding to deepfake-induced  reputational threats therefore presents a unique challenge for organizations. Despite the growing prevalence of deepfake technology, little experimental research has examined how different crisis communication strategies perform in mitigating the reputational and relational harm posed by deepfake-induced crises. Accordingly, this study seeks to (1) examine how exposure to deepfake news relates to public perceptions and affect toward …

Development And Implementation Of Educational Modules On Management Of Neonates With Critical Congenital Heart Disease In The Delivery Room (Learn-Chd)., Noorjahan Ali, Brenda Law, Alyssa R. Thomas, Philip T. Levy, Ruby Gupta, Summer Elshenawy, Danielle Reed, Leeann R. Pavlek, Jennifer Shepherd, Sharada H. Gowda, Molly K. Ball, Beth Ann Johnson, Chloe Joynt

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Neonates with congenital heart disease may require delivery room interventions beyond standard care. Because existing guidelines and educational programs rarely address these needs, we developed and evaluated targeted educational modules.

METHODS: Teams were randomized to online eLearning modules or directed readings. Individual pre-/post-knowledge scores were compared. Team performance was tested in simulated delivery scenarios including abruption, hypoplastic left heart syndrome, d-transposition of great arteries and congenital complete heart block.

RESULTS: 32 teams from 9 centers participated. The module group had improved knowledge scores (mean change 6% vs -0.3% e-Learning group, p = 0.01). Simulation performance was similar between groups …

Immediate Postoperative Pacing Dependency Is Not Associated With Worse Mid-Term Survival In Redo Mitral Valve Surgery, Devon Kelley, Joyce Ho, Andrew Belec, Takahiro Tashima, Victoria Li, James Lao, Varun Kathawate, Kazuhiro Ueno, Amit Iyengar, Jessica Dominic, Pavan Atluri

Division of Cardiology Faculty Papers

Risk factors (RF) for permanent pacemaker (PPM) placement in cardiac surgery include valvular operations and redo operations. We aim to identify RF for PPM placement prior to discharge (DC) specifically among redo mitral valvular operations, and to analyze outcomes in this population. Our retrospective review considered 943 patients undergoing redo MV operations between 01/2002 and 12/2021, excluding patients experiencing in-hospital death within 48 hours of their operation and patients with existing PPM or implanted cardiac defibrillator (ICD). Patients (n = 742) were categorized based on whether they received a PPM before DC or not. Of the 742 patients analyzed, 47 …

Learning Across Borders Through Outbreak Investigation: A Mixed-Methods Evaluation Of An International Collaborative Workshop For Medical Students, Maysa Falah, Michael Dillon, Delphine Kayem, James Edwards, Jonah Fox, Latifa Adarmouch

Faculty of Health Datasets

Public Data set

Permanent Winter Hay-Feeding Stations Concentrate Soil Nutrients In Kentucky Pastures, Alan J. Franzluebbers, Jeffrey W. Lehmkuhler, Matt H. Poore, Arjun Kafle, Rodolfo Zentella, Tommy Yankey, S. Ray Smith, Gregory Halich

Animal and Food Sciences Faculty Publications

Distribution of soil nutrients as a function of centralized winter hay-feeding stations can lead to inefficient nutrient utilization and environmental quality concerns, but distributions have not been adequately characterized across a diversity of soils. We investigated spatial distribution of soil nutrients and organic matter fractions on three farms with concrete feeding pads for winter hay feeding. Soils were silt loam at the Princeton and Oran Little Research Stations and silty clay loam and silty clay at the Eden Shale Farm in ≥20-year-old tall fescue (Lolium arundinaceum) pastures in Kentucky. An anticipated impact zone of 0.7–1.0 ha around the winter hay-feeding …

Draft Final 2023 Unreclaimed Sites Sampling: Ur-42 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

From Evolution To Revolution: Narrowing The Technological Skills Gap Of Accounting Graduates, Geraldo Vasquez, Frank Manzi, Mark Martinelli, Cynthia Scarinci

Journal of Global Education and Research

A growing number of firms have cited the lack of technological skills that college graduates entering the accounting profession exhibit, raising concerns about their ability to serve clients effectively. Yet accounting graduates are not exposed to new technologies in the classroom or on the Certified Public Accountant (CPA) exam. The CPA Evolution initiative aims to restructure the CPA Exam to ensure that graduates have the technological skills to enter the profession and assist educators with transitioning to the new exam through the development of the CPA Evolution Model Curriculum. We argue that although the redesigned CPA exam and the Model …

Religious Higher Education In Prison In The United States: The Importance Of Well-Being, Robin L. Labarbera

Journal of Global Education and Research

A growing body of scholarship suggests that incarcerated individuals who participate in education programs, particularly those grounded in faith, are better positioned for lasting community reintegration and positive long-term outcomes. Using a mixed-methods evaluation design, the author examines two interrelated questions: whether faith-based higher education is associated with enhanced well-being among current participants and whether program graduates carry those well-being gains into post-release life. Drawing on group interviews with 109 incarcerated men and women across six U.S. facilities and surveys from 157 participants in four states, the study found that participation in a prison-based theological education program was associated with …

Bridging The Gap: Addressing Challenges And Enhancing Support For Learners Transitioning From Primary To Secondary School, Redson Nkosi, Precious Nyoni, Philogene Manirahari

Journal of Global Education and Research

This study explored the challenges students face during the transition from primary to secondary school, particularly in their final year of primary and first year of secondary school. Common concerns include bullying, making new friends, increased workload, unfriendly teachers, teasing, new subjects, and adjusting to the secondary school environment. Conducted in Malawi, Mzimba North education district at two secondary schools and one primary school, the research used a qualitative methodology, employing documentary review, interviews, focus group discussions, and observations for data collection. Findings revealed that many of the students’ fears were either confirmed, such as bullying and teacher strictness, proving …

Broadband Diffusion And Digital Preparedness In Tanzania: Harnessing The Role Of Technology In Formal Education, George Matto, John J. Iwata

Journal of Global Education and Research

Broadband, as a high-speed Internet connectivity, is an essential enabler for digital preparedness. However, little is known, in the case of Tanzania, about the nexus between broadband diffusion and digital preparedness, particularly in the facilitation of the teaching and learning process. This study, therefore, aimed at investigating the nexus between broadband diffusion and digital preparedness in Tanzania by focusing on the country’s readiness to leverage the same for formal education. The study employed a systematic review, guided by the PRISMA framework, to obtain the empirical evidence from existing literature. Thematic analysis was used to identify themes, analyze, and interpret qualitative …

Who Lives In Ambulance Deserts? Demographic And Geographic Differences In Accessing Ambulance Services, Yvonne Jonk Phd, Heidi O'Connor, Brianna Holston Bsph, Celia Jewell Rn, Mph, Tyler Deangelis

All Maine Rural Health Research Center Publications

Building upon the original May 2023 Ambulance Deserts Chartbook, this study characterizes who lives in ambulance deserts (AD), defined as populated areas that are more than 25 minutes from an ambulance station. Using ambulance location data obtained from 41 states (2021-2022) and the 2016- 2020 American Community Survey (ACS) five year estimates, this study identifies systemic gaps in access to ambulance services by analyzing differences in the following characteristics of AD and nonAD populations: age, sex, race/ethnicity, education, household income, poverty levels, employment, health insurance status, and rural-urban county location.

Peaks Island Star : July 2026, Vol. 46, Issue 7, Service Agencies Of The Island

Peaks Island Star, 2026

The Peaks Island Star is the newsletter of the island's service agencies and other community news.