Digital Commons Network^™

Effects Of Auricularia Auricula Polysaccharides On Its Rehydration Characteristics, Su Xin, Lu Huiwei, Liu Zhou, Chai Zhenyu

Food and Machinery

[Objective] To explore the effects of Auricularia auricula polysaccharides on its rehydration characteristics. [Methods] Auricularia auricula polysaccharides are extracted by the hot water-ultrasonic-assisted extraction method. The polysaccharide-removed Auricularia auricula residue is dried to a constant weight and rehydrated. Then, the water content, swelling, rehydration ratio, texture characteristics, and water distribution state of the rehydrated Auricularia auricula are determined to explore the effects of Auricularia auricula polysaccharide content on its rehydration characteristics. [Results] The crushing degree of Auricularia auricula is proportional to the polysaccharide removal rate. Compared with Auricularia auricula and polysaccharide-removed Auricularia auricula of 20~16 mesh, the polysaccharide-removed Auricularia auricula …

An Analytical Review Of Brainwave Analysis For Mind-Controlled Drones: Utilizing Hybrid Neural Networks And Motor Imagery, Ather Salah Hadi Al-Isawi, Sufri Muhammad, Novia Indriaty Admodisastro, Siti Anom Ahmad, Raihani Mohamed

Baghdad Science Journal

Brain-computer interfaces (BCIs) provide direct drone control by interpreting motor imagery brain impulses. This review paper critically assesses the progress made in using hybrid neural networks and motor imagery to operate mind-controlled drones and addresses the challenges of encoding and decoding complex brain signals for precise and reliable drone control. In this review paper, the primary objective is to analyze and synthesize the latest brainwave analysis technologies, focusing on hybrid neural networks and motor imagery tasks for drone control via brain-computer interfaces. This study aims to provide insights into the effectiveness of these technologies in enhancing the accuracy and reliability …

Prevalence And Molecular Characterization Of Non-Typhoidal Salmonella In Poultry Of Dar Es Salaam, Tanzania, Tumwi T. Salah, Paulo S. Joseph, Bishop I. Magidanga, Richard S. Mwakapuja, Victor A. Makene

Tanzania Journal of Science

Poultry is one of the common source of non-typhoidal Salmonella and poultry products are the major sources of human and animal infections with the Salmonella. A cross-sectional study was conducted to determine the prevalence of non-typhoidal Salmonella in live commercial and backyard chickens from retail markets and farms in Dar es Salaam city, Tanzania. The study was conducted in four districts; Ubungo, Kinondoni, Temeke and Ilala. A total of 400 chickens (120 broilers, 120 layers and 160 backyard chickens) were tested for Salmonella. Salmonella isolation and identification was carried out using bacteriological standard methods and polymerase chain reaction (PCR) …

Development Trends And Priority Research Fields Of Electrochemical Discipline In The 15th Five Year Plan Period, Lin Zhuang, Wen-Bin Cai, Heng-Xing Ji, Qing Li, Gong-Wei Wang, Sen Xin, Qing Zhao, Fang-Yi Cheng, Yu-Guo Guo, Lan-Qun Mao, Yang Tian, Fei Wu, Li-Min Zhang, Yan Xiang, Jin-Song Hu, Rui Cao, Li Xiao, Hua-Bing Tao, Wei Xing, Dong-Ping Zhan, Hong-Gang Liao, Mei-Ling Xiao, Bin Ren, Zhang-Quan Peng, Rui Wen, Xiang Wang, Yue-Feng Song, Hou-Fu Lv, Bao-Yu Xia, Guo-Xiong Wang, Jun Cheng, Zhi-Pan Liu, Min Zhou, Bing Huang, Cun-Pu Li, Yu-Qin Zou, Shuang-Yin Wang, Hai-Bo Lin, Zi-Dong Wei

Journal of Electrochemistry

In fulfillment of the national science-and-technology development agenda, the Department of Chemical Sciences of the National Natural Science Foundation of China (NSFC) convened the Strategic Symposium on the Fifteenth Five-Year (2026–2030) Development Plan for Electrochemistry held in Xiamen on 29 August, 2025—the culminating year of the Fourteenth Five-Year (2021–2025) Development Plan. More than forty leading experts in the field of electrochemistry participated with spanning nine thematic fronts: Interfacial Electrocatalysis, Interfacial Electrochemistry for Energy Storage, Bioelectrochemistry, Electrochemistry of Hydrogen Energy, Electrochemical Micro-/Nano-Manufacturing, Operando Electrochemical Characterization, Electro-Thermal Coupling Catalysis, Theoretical and Computational Electrochemistry, and Electrochemical Synthesis. The forum assembled China’s foremost electrochemical …

Produce Flow Food Safety Plan With Wash Pack Flow Template, Mary S. Choate

UNH Cooperative Extension

No abstract provided.

The Roles Of Sirt1 In Breast And Gynecologic Malignancies, Jianmin Ding, Matthew T Ye, Songlin Zhang

Faculty, Staff and Students Publications

Sirtuin 1 (SIRT1), an NAD+-dependent histone deacetylase, exerts complex and context-dependent effects in breast and gynecological cancers. By deacetylating histone and non-histone proteins such as p53, FOXO, and NF-κB, SIRT1 regulates essential processes including DNA repair, apoptosis, metabolism, and stress response. In breast cancer, SIRT1 may act as a tumor suppressor in early stages by maintaining genomic stability but promotes epithelial–mesenchymal transition, metastasis, and chemoresistance in aggressive subtypes such as triple-negative breast cancer. Similarly, in gynecological cancers, SIRT1 displays dual roles: promoting proliferation via estrogen signaling and p53/FOXO1 inhibition in Type I endometrial cancer yet potentially supporting DNA repair in …

From Listening To Action: Building Effective Community-Academic Partnerships In Environmental Health [Lightning Talk], Dani Mcbride

University Faculty Publications and Creative Works

The slides from a lightning talk given at the Michigan Premier Public Health Conference in Muskegon, MI on October 28, 2025.

Factor Structure Of Food And Physical Activity Parenting Practices Among Us Fathers By Ethnicity And Survey Language: A Cross Sectional Study, Salma M A Musaad, Louise C Mâsse, Alicia Beltran, Oriana Perez, Teresia M O'Connor

Children’s Nutrition Research Center Staff Publications

Background: Parenting practices contribute to children’s eating and physical activity behaviors, and thereby their risk of obesity and associated medical conditions. Fathers may engage in different parenting practices than mothers. The objective of this study was therefore to establish psychometrically sound tools in English and Spanish for measuring Physical Activity Parenting Practices (PAPP) and Food Parenting Practices (FPP) for Hispanic and non-Hispanic fathers of diverse races for use in future studies, such as evaluations of family-based obesity interventions targeted at fathers.

Methods: We conducted a preliminary assessment of the psychometric properties of a reduced version of the PAPP and FPP …

Selective Rna Sequestration In Biomolecular Condensates Directs Cell Fate Transitions, Patrizia Pessina, Mika Nevo, Junchao Shi, Srikanth Kodali, Eduard Casas, Yingzhi Cui, Alicia L Richards, Emily J Park, Xi Chen, Florencia Levin-Ferreyra, Alejandra Rivera Tostado, Erica Stevenson, Nevan J Krogan, Danielle L Swaney, Qilong Ying, Qi Chen, Justin Brumbaugh, Bruno Di Stefano

Faculty, Staff and Students Publications

Controlling stem cell differentiation is a longstanding goal in biomedical research. Here we explore how cell fate is influenced by RNA condensates, specifically P-bodies, which modulate gene expression posttranscriptionally. We profiled the transcriptomes of biomolecular condensates in diverse developmental contexts spanning multiple vertebrate species. Our analyses revealed conserved, cell type-specific sequestration of untranslated RNAs encoding cell fate regulators. P-body RNA contents do not reflect active gene expression in each cell type but are enriched for translationally repressed transcripts characteristic of the preceding developmental stage. Mechanistically, P-body contents are controlled by microRNAs and can be profoundly reshaped by perturbing AGO2 or …

Association Of Stepping-Up To High Dose Inhaled Corticosteroids And Risk Of Future Asthma Exacerbations: Data From The Us, Trung N Tran, Marjan Kerkhof, Tham T Le, Mina Khezrian, Nicole Zubizarreta, Joshua Enxing, Kirsty Rhodes, Jonatan Hedberg, Bill Cook, Tianshi David Wu, Tim W Harrison

Faculty, Staff and Students Publications

Background: Real-world data on the benefit of high-dose inhaled corticosteroid (ICS) post-exacerbation are limited.

Objective: To investigate whether stepping-up to high-dose inhaled corticosteroid (ICS) post-severe exacerbation reduces future asthma exacerbation risk in a real-world setting.

Methods: This was a retrospective cohort study using the Optum® Clinformatics® database (October 2015-December 2023). Patients with asthma, aged ≥12 years, with ≥1 severe exacerbation and ≥2 ICS maintenance prescriptions in the 12-months pre-, and ≥1 ICS maintenance prescription in the 3-months post-exacerbation were included. Primary and secondary endpoints were annualized asthma exacerbation rate (AAER) and time to first subsequent severe exacerbation, respectively. We compared …

Screening For Trypanosoma Cruzi In Patients Living With The Human Immunodeficiency Virus (Pwh) In The Peruvian Amazon, Silvia Otero-Rodriguez, Martin Casapia-Morales, Lilia-Lorena Pinedo-Ramirez, Esperanza Merino, Eva H Clark, José-Manuel Ramos-Rincón

Faculty, Staff and Students Publications

Introduction: Chagas disease (CD) - Trypanosoma cruzi infection - in people living with HIV (PWH), particularly those with advanced CD4 T cell depletion, can lead to severe syndromes affecting the central nervous system and the heart.

Methods: We performed a cross-sectional study to screen for CD among PWH in Iquitos, Peru, between October 2023 and May 2024, with the objective of understanding the frequency of infection in this population. Adults with confirmed HIV attending outpatient services at two regional hospitals were enrolled. Two ELISA tests (lysate and recombinant) were used, and discordant results were adjudicated by indirect chemiluminescence immunoassay (CLIA). …

Molecular And Cellular Characterization Of Planarian Stem Cell Microenvironments, Frederick G Mann, Carolyn E Brewster, Dung M Vuu, Mol Mir, Riley Galton, Shao-Fu Nien, Enya R Dewars, Carlos Guerrero-Hernández, Jason A Morrison, Mary C Mckinney, Lucinda E Maddera, Melainia L Mcclain, Kate E Hall, Seth Malloy, Shiyuan Chen, Brian D Slaughter, Sean A Mckinney, Stephanie H Nowotarski, Anoja Perera, Blair W Benham-Pyle, Alejandro Sánchez Alvarado

Faculty, Staff and Students Publications

Stem cell niches are essential for regulating stem cell self-renewal and differentiation during tissue repair and regeneration. However, the mechanisms supporting stem cell function in highly regenerative organisms, such as the freshwater planarian Schmidtea mediterranea, remain unclear. Using spatial transcriptomics, we identified two cell types associated with planarian stem cells: secretory cells we term "hecatonoblasts" and intestinal cells. Surprisingly, while hecatonoblasts were in close physical proximity to stem cells in the mesenchyme, they were dispensable for regeneration. In contrast, intestinal cells, despite lacking direct contact with stem cells, regulated both their position and function during regeneration. Electron microscopy revealed diverse …

Cd7 Regulates The Persistence Of Terminally Exhausted Cd8 T Cells During Chronic Infection, Sean Hyslop, Colby J Hofferek, Maria V Stegantseva, Emerald Kan, Kelli A Mccord, Victor M Alvarez, Amanda Y Xia, Jacob P Conarty, Andreas Wieland, William H Hudson

Faculty, Staff and Students Publications

CD8+ T cell exhaustion limits immune responses during cancer and chronic infection. We identify CD7 as a tissue-specific regulator of terminally exhausted CD8+ T cells during chronic infection. CD7 expression progressively increases during exhaustion, reaching its highest levels on a subset of CD101+Tim3low terminally exhausted cells that arise in the liver. Transcriptomic analysis revealed that CD7-deficient terminally exhausted cells display altered expression of co-stimulatory, translational, and effector genes, correlating with markedly reduced persistence and increased apoptotic susceptibility. Importantly, CD7 is preferentially upregulated on PD-1+CD39+ tumor-infiltrating lymphocytes (TILs) in human head and neck squamous cell carcinoma (HNSCC), suggesting CD7 may play …

Collecting Hurricane Katrina Oral Histories: Amplifying Campus Voices, Chandler D. Smith

Library Faculty Publications

Background: A look at the process of the creation of an oral history project about Hurricane Katrina at LSU Health New Orleans Libraries.

Description: Hurricane Katrina was a major event for our campus and region. This year is a major anniversary of the event, and we wanted to memorialize the hard work, struggles and stories people had about Hurricane Katrina and its recovery. A search was done to see what oral histories had been done about Hurricane Katrina. Next, we checked with our Institutional Review Board (IRB) to see if approval was needed for the project. Our IRB determined that …

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Butte Treatment Lagoons (Btl) Groundwater Treatment System Routine Operations, Maintenance, And Monitoring (Om&M) Plan (Dated August 29, 2025), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Conditional Approval Letter For The Butte Priority Soils Operable Unit Clark Tailings Consolidated Waste Management Area Site Investigation Quality Assurance Project Plan Revision 0 (2025 Update) And Response To Epa Comments. (Dated September 16, 2025), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Real-World Data For Tisagenlecleucel In Patients With R/R B-All: Subgroup Analyses From The Cibmtr Registry., Samuel John, Kevin J. Curran, Erin Hall, Amy K. Keating, Susanne H C Baumeister, Sarah Nikiforow, Timothy Driscoll, Amy Moskop, Kevin O. Mcnerney, Christine L. Phillips, Michael A. Pulsipher, Emily M. Hsieh, Rayne H. Rouce, Marcelo C. Pasquini, Ranjan Tiwari, Jennifer Willert, Roberto Ramos, Joerg Krueger, Erin Guest, Stephan A. Grupp

Manuscripts, Articles, Book Chapters and Other Papers

Since the first approval of tisagenlecleucel in 2017, pediatric and young adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) may receive this CD19-directed chimeric antigen receptor T-cell therapy. We report real-world data from the Center for International Blood and Marrow Transplant Research (>2.5 years of follow-up). As of 4 May 2022, 768 patients with B-ALL had received tisagenlecleucel. Patients aged ≥18 and < 18 years of age (including those < 3 years) were treated during first relapse (26.6% and 26.7% [< 3 years, 44.8%], respectively) or primary refractory disease (12.4% and 12.1% [< 3 years, 15.5%], respectively) with 17.6% and 11.6% (< 3 years, 13.8%), respectively, having high disease burden (≥50% bone marrow [BM] blasts) and 20.2% and 20.2% (< 3 years, 13.8%), respectively, having low disease burden (>0 to < 5% BM blasts). Among patients with ≥12 months postinfusion follow-up (n = 578; median follow-up, 32.1 months), the best overall response of complete remission/complete remission with incomplete blood count recovery was 86.0%. The 12-month relapse-free survival (RFS) and overall survival (OS) were 61.8% and 79.4%, respectively, whereas the 24-month RFS and OS were 50.3% and 63.8%, respectively. Age (< 18 years) and disease burden (< 50% BM blasts) were associated with better outcomes. Previous inotuzumab therapy and KMT2A rearrangement were associated with worse outcomes. Older patients (≥18 years) experienced a higher rate of any-grade cytokine release syndrome (CRS) associated with higher disease burden before infusion. Any-grade CRS and neurotoxicity were lower in patients aged < 3 years. Extended follow-up continues to demonstrate high rates of RFS and favorable safety in this population.

Effect Of Valemetostat On The Pharmacokinetics Of Midazolam And Digoxin: A Phase 1 Drug-Drug Interaction Study In Patients With Non-Hodgkin Lymphoma, Masaya Tachibana, Steven Horwitz, Eric Jacobsen, Francine Foss, Pamela Allen, Pierluigi Porcu, Tatyana Feldman, Jia Ruan, Jonathan Brammer, Jie Wang, Shinichi Inaba, Yuka Iko, Keiko Nakajima, Yasuyuki Kakurai, Noriaki Kitami, Yang Chen, Yvonne Lau

Department of Medicine Faculty Papers

Valemetostat tosylate (valemetostat) is an oral, potent, dual inhibitor of enhancer of zeste homolog (EZH)2/1, under investigation in non-Hodgkin lymphomas (NHLs) and solid tumors. In vitro, it inhibits cytochrome P450 3A (CYP3A) and P-glycoprotein (P-gp) when combined with sensitive CYP3A or P-gp substrates. This drug–drug interaction (DDI) sub-study is part of the phase 1 trial of valemetostat monotherapy (DS3201-A-J101; NCT02732275), assessing the effect of valemetostat on the pharmacokinetics (PK) of sensitive CYP3A and P-gp substrates midazolam and digoxin, respectively, in patients with relapsed or refractory NHL, and its safety and efficacy. Patients received two simultaneous single doses of midazolam and …

The Meaning Of Happiness Among Urban Children And Adolescents In Indonesia: A Qualitative Study Through Drawings, Eko Handayani, Dewi Maulina, Winarini W. Dahlan

Psychological Research on Urban Society

Urban children and adolescents face various stressors, including academic pressure, digital media exposure, and limited green spaces, which influence their happiness perception. This study aims to explore the meaning of happiness in children and adolescents living in Indonesia’s urban areas through qualitative research using a drawing-based approach. A total of 243 participants, aged 9-15, from elementary and junior high schools in Jakarta, were asked to draw "I am happy when..." with written brief explanations. Data were analyzed using visual and narrative-thematic approaches across children and adolescents from a developmental psychology perspective. The findings reveal that the images and explanations of …

Balispirit Festival As A Regenerative Event Transformation Model: The Tri Hita Karana Framework In Support Of Sustainable Spiritual Tourism, Maha Dewi

Journal of Indonesian Tourism and Policy Studies

The global tourism sector is undergoing a transition toward Regenerative Tourism (RT). RT emphasizes active ecosystem restoration and community empowerment, surpassing the objectives of passive sustainability. In Bali, this transition appears in the Trilogy of Serenity, Spirituality, and Sustainability. This study examines the BaliSpirit Festival (BSF) as a case study that operationalizes the local Tri Hita Karana (THK) philosophy. This philosophy integrates spiritual (Parhyangan), social (Pawongan), and environmental (Palemahan) harmony as its foundation. The study uses a descriptive-analytical qualitative methodology to evaluate BSF's practices in advancing Sustainable Spiritual Tourism (SST). Results show BSF has established a culturally grounded regenerative event …

Digital Marketing Opportunities For The Advancement Of The Tourism Industry Case Study: Indihome Pt. Telekomunikasi Indonesia, Abiyyu Sangaji

Journal of Indonesian Tourism and Policy Studies

Digital marketing is becoming increasingly important in the tourism industry as a way to reach a wider target market and increase sales. This study uses a qualitative descriptive method aimed at exploring digital marketing opportunities in the tourism industry through a case study of IndiHome PT. Telekomunikasi Indonesia. The results of the study indicate that digital marketing can provide significant opportunities for the tourism industry, particularly in terms of the use of social media, websites, and engaging visual content. Furthermore, the results also show that the use of data and analytics can help companies optimize their digital marketing campaigns. However, …

Laura Honegger, Ph.D., Lcsw, Laura Honegger

Faculty Research Mixer

No abstract provided.

Professor Alex Liu, Alex Liu

Faculty Research Mixer

No abstract provided.

Embracing Artificial Intelligence And Digital Health In Cancer Care, Pavitra P. Krishnamani

Advances in Cancer Education and Quality Improvement

Digital health technologies like AI, telemedicine, and wearables are revolutionizing cancer care by enabling earlier detection, personalized treatment, and improved patient support and access.

A Cancer Haiku Triptych, Larry C. Driver

Advances in Cancer Education and Quality Improvement

This trio of patient-inspired Haiku attempts to capture the joyful optimism of cancer-free life in the first pair of spring and summer, with a hint of transition in the second, and the final autumn into winter piece heralding the realization that smoldering cancer has flared-up with the possibility of the end of life.

Impact Of Clinical Decision Support Tool Implementation On Injectable Calcitonin Usage, Petar Jordanov, Ashley Crouch, William Towers

Advances in Cancer Education and Quality Improvement

Calcitonin injection is a high-cost medication used to treat hypercalcemia in hospitalized patients. Many institutions have implemented strategies to reduce unnecessary use or waste of calcitonin, including dose rounding, formulary restriction criteria, and limiting the number of doses a patient may receive. MD Anderson Cancer Center (MDACC) utilizes approximately 1200 calcitonin doses per year with no current formulary or dosing restriction criteria. The goal of this study was to evaluate patterns of use of calcitonin at MDACC and implement and evaluate the impact of clinical decision support tools to reduce unnecessary calcitonin use and waste. This is a single-center quality …

Streamlining Nuclear Theranostic Clinic Workflow, Charisma Desai, Anne Fisher

Advances in Cancer Education and Quality Improvement

Nuclear medicine clinic needs have drastically changed with the emergence of theranostics, exciting new agents in the fight against cancer. However, administering these agents is a resource-intensive task, increasing demand for physician consultation time with patients, clinic office space, and scanner time. We examined our institution’s nuclear medicine clinic workflow and interviewed the clinic’s front desk staff, technologists, nurses, managers, physicians, and patients to find sources of delays, dissatisfaction, and decreased efficiency. An Ishikawa diagram and decision matrix helped us determine the most impactful intervention with our available resources. For this cycle, we focused on the consent process. Theranostic patients …

Interactive Clinical Dashboard For Psychiatric Oncology Services At A Cancer Institution: A Quality Initiative, Maria Shabih, Adelita D. Martinez, Alan D. Valentine, Deepti A. Chopra

Advances in Cancer Education and Quality Improvement

Accurate documentation of reasons for psychiatry consultations is critical for developing an effective treatment plan for the patient and improving quality of care through targeted interventions. The purpose of this project was to create an interactive dashboard on Power BI. We downloaded the report from Epic on SAP BI. On an Excel sheet, we recoded the reason for consults and categorized using a keyword list and recoded the consults into distinct, categories such as "anxiety," "depression," and "altered mental status (AMS)," with data spanning 2 fiscal years.

Key findings from the dashboard revealed that anxiety and depression accounted for most …

Balancing Pressure And Support - Examining Burnout And Mental Health In Teenage Athletes, Liberty University

Sport Leadership Summit

Analyzing the relationship between coaching styles and athlete burnout. It is an important and interesting topic because over the last few years participation in youth sports has dropped, this is an issue because sports teach valuable lessons. The topic is plausible because it can survey athletes and use that information to help.

The Beauty Of Uniquity - A Regression Analysis Of Mlb Pitchers With Anomalous Arm Angles, Liberty University

Sport Leadership Summit

This study examines the effect of arm angle on pitcher success and the potential for injury prevention based on arm angle. With the rise of advanced metrics like Statcast, pitcher mechanics—especially arm angle—have become key indicators of performance. The research explores how different arm angles influence pitch movement, velocity, and injury risk, suggesting that pitchers with a “low ¾ arm angle” may best balance performance and long-term arm health.