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Work-Related Pathology At Tell El-Amarna: The Physical Cost Of Building A New Capital City In The New Kingdom, Egypt, Heidi Suzanne Davis

Graduate Theses and Dissertations

This dissertation examines patterns of work-related indicators of physical stress in a skeletal sample from the non-elite adult population of the South Tombs Cemetery (STC) of Amarna, Egypt. Assessing work-related pathology using an integrative model of physical stress, this study considers the interactions of demographic parameters of age, sex, and injury recurrence, along with archaeological and documentary data to provide a biocultural contextual approach to physical stress in this population. The STC sample is compared to other samples from Egyptian and Nubian sites as well as historical samples believed to be under high physical demands and stressful conditions. The STC …

Micro-Greens, Not Micro-Yellows: Evaluating Dehydration-Based Preservation Techniques For Reducing Foodborne Pathogens And Quality Preservation On Microgreens, Travis S. Sananikone

Graduate Theses and Dissertations

Microgreens are increasingly popular among consumers due to their high nutritional value. However, their limited shelf-life remains a significant challenge. To extend their usability, small-scale growers increasingly apply home preservation methods like warm air drying or freeze-drying. However, the effects of these methods on common foodborne pathogens are not well understood. Radish and alfalfa microgreens were inoculated with cocktails of Salmonella enterica, Escherichia coli O157:H7, and Listeria monocytogenes 4b (ca. 8.0 log CFU/g). Treatments included dehydration in a commercial dehydrator, freeze-drying (-20°C, 24 h), and convective drying in an oven (60°C for 4 h), and convective drying in an oven …

Predictive Factors Of Academic Success During Transition To Undergraduate Studies In Stem Programs In Kansas, Elizabeth L. Butler

Electronic Theses and Dissertations

In tThis dissertation the researcher exploreds the correlations between high school GPA, ACT Math, ACT cComposite scores, and first -semester GPA for first-time freshmen at a mid-sized university in the Midwest. This quantitative correlational study uses multiple regression analysis to discover correlations that may exist between these interval variables. Data for this study was collected through a request to the study site’s oOffice of pPlanning and aAnalysiss at the university and was all archival data at a record level for the students. Data had been collected through the admissions process and was stored in Banner and SLATE, both data management …

Secondary Special Education Teachers: Perceptions On Burnout Since The Start Of Covid-19, Regina Perez

Electronic Theses and Dissertations

This study examined burnout among secondary special education (SPED) teachers following the COVID-19 pandemic, which significantly disrupted education and intensified teacher stress. Burnout, defined by emotional exhaustion, depersonalization, and reduced personal accomplishment, has been linked to teacher attrition and decreased student achievement. The problem addressed was the increased levels of burnout and stress among SPED teachers and the lack of sufficient administrative support to mitigate these effects. The purpose was to explore SPED teachers’ perceptions of burnout since the pandemic and identify the supports needed to reduce it. Using a qualitative case study design grounded in Maslach’s burnout theory, the …

Consequences Of Secondary Traumatic Stress On Individuals Without Formal Psychological Training Working With Trauma-Exposed Children, Juan F. Valdez

Electronic Theses and Dissertations

Literature has suggested that secondary traumatic stress could cause various adverse effects for individuals working with trauma-exposed populations. However, direct care workers performing in shelters designed to serve unaccompanied immigrant children are faced with the task of caring for these minors who may have been exposed to trauma in their home countries, while traveling to the United States, or after arriving in the country. This qualitative case study was conducted to understand and describe the experiences of 15 current employees and five ex-employees who have worked with unaccompanied children for at least a year. These individuals participated in in-depth personal …

Cefadroxil-Induced Drug Reaction With Eosinophilia And Systemic Symptoms (Dress) Syndrome After Double Mastectomy For Ductal Carcinoma In Situ: A Case Report, Iyawnna Hazzard, Alexandra Hong, Darius J. Shahbazi, Shahin Shahbazi

Student Publications

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a delayed hypersensitivity reaction to medications, characterized by a prodrome of malaise and fever, followed by skin and hematologic manifestations and end-organ damage. Typical causal agents of DRESS syndrome include allopurinol, aromatic anticonvulsants, and antibiotics. However, fewer than 3% of cases suggest cephalosporin-induced DRESS syndrome.

A 43-year-old female developed a diffuse, erythematous, pruritic rash encompassing her whole body after starting prophylactic cefadroxil therapy before a double mastectomy for ductal carcinoma in situ. Her rash continued to worsen despite discontinuation of cefadroxil and developed a fever, myalgias, and generalized weakness. In …

Antipsychotic Misuse: A Silent But Growing Public Health Hazard, Sumeet Bhardwaj, Karisma Pathak, Myra Mclenon, Steven Spector, Kevin Tu

Student Publications

Antipsychotic drugs are essential in the management of schizophrenia, bipolar disorder, and other psychiatric illnesses, but their use is closely linked to cardiometabolic side effects. Cardiometabolic side effects include weight gain, dyslipidemia, glucose intolerance, and increased cardiovascular morbidity and mortality. Mechanisms of cardiometabolic side effects involve disruption of the central nervous system’s ability to regulate appetite, peripheral metabolic effects, which are changes in metabolism outside the CNS, and receptor-level interactions, with second-generation antipsychotics generally posing a greater risk than first-generation agents. This review addresses current evidence on the cardiometabolic consequences of antipsychotic therapy, increasing inappropriate off-label use of antipsychotic drugs, …

A Multi-Center Retrospective Cohort Study Of Neurosarcoidosis Myelitis: Current Observations And Future Directions, Giovanna S Manzano, David B Clifford, Steven Richard Dunham, Masoud Majed, Et Al.

2020-Current year OA Pubs

OBJECTIVE: The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales.

METHODS: Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers. Cases were analyzed by initial treatment. The primary outcome was T1 post-contrast gadolinium enhancement resolution at 6 months post-treatment. Secondary outcomes were changes in modified Rankin scale (mRS) and Expanded Disability Status Scale (EDSS) from nadir to final follow-up.

RESULTS: Two hundred two patients were identified (median diagnosis age: 47 years (IQR 39-55); male: female 1.3:1). Median nadir mRS and …

Environmental Beliefs Among Evangelical Leadership, Jeffrey Stark

Dissertations

There has been consensus among climate scientists for over a decade about the reality of human caused climate change. Even with this consensus, the public understanding of this issue remains divided based on factors generally unrelated to the science. Evangelical Protestants are one group which consistently polls as more skeptical of climate change. This is true not only when compared to the general population but also when compared to other religious demographics. Most large-scale surveys of evangelicals assume the demographic to be a monolith and do not attempt to break the demographic down further. In this mixed methods study, we …

Judicial Ethics, The Supreme Court, And The Rule Of Law, Charles G. Geyh

Articles by Maurer Faculty

This Essay begins with a short history of judicial ethics regulation in the United States, ending with the adoption of codes of conduct by every state and federal judicial system except the Supreme Court of the United States. It then turns to a series of ethics controversies encircling the Supreme Court and its justices, which culminated in the Supreme Court adopting a Code of Conduct in 2023. Tapping into the social science literature, it argues that for codes to improve the ethical climate of an institution they must encourage psychological ownership of and “buy-in” to a code by those subject …

Studies On Curcumin-Glucoside In The Prevention Of Alpha-Synuclein Aggregation, Lakshmi Sowmya Emani, Jayanth K. Rao, Jagadeesha Kumar Dasappa, Marisín Pecchio, Johant Lakey-Beitia, Hansapani Rodrigo, Jessica Cruz-Mora, Priya Narayan, Nikhilesh Anand, Bharathi Gadad

School of Medicine Publications

Background: α-synuclein (α-syn) deposition in the mid-brain region is one of the hallmark pathologies of Parkinson's disease (PD). The key steps involve the transformation of α-synuclein into a toxic oligomer and insoluble fibrillar aggregates.

Objective: To understand the role of curcumin-glucoside in the prevention of α-syn aggregation, a mechanistic approach.

Methods: In the present study, we synthesized a novel molecule, curcumin-glucoside (Curc-gluc), to improve the water solubility and partition coefficient, making the molecule with high bioavailability. The present study is focused on understanding the α-syn aggregation kinetics in the presence and absence of Curc-gluc, curcumin (Cur), copper (Cu), and iron …

Nanotechnology Strategies For Endometrium Health: Are We On The Right Track?, Victoria Herrera, Dana Tarab-Ravski, Subhash Chauhan, Nikesh Narang, Mohammad Mirazul Islam, Dan Peer, Rajendra Prasad, Murali Yallapu

School of Medicine Publications

The endometrium is a vital mucosal tissue which undergoes cyclical regeneration, differentiation, and remodeling upon hormonal, cellular, and molecular signaling networks. Dysregulation of these processes can trigger a range of pathological conditions including chronic inflammatory disorders, hyperplastic lesions, malignancies, and infertility, necessitating the need for effective therapeutic interventions. Furthermore, we are still dependent on conventional treatment modalities which are often constrained by inefficient drug biodistribution, systemic toxicity, and emergence of therapeutic resistance. Recently, nanomedicines have gained tremendous attention in human healthcare, because they not only diagnose the disease but also deliver therapeutic agents to the targeted site without affecting healthy …

From Molecules To Models: A Holistic Review Of Autism Spectrum Disorder Mechanisms And Research Tools, Sriya Gullapalli, Lois Baldado, Megan W. Szobody, Anesu K. Murambadoro, Kevin Garcia Valdez, Arjun Bellamkonda, Daniela Gonzalez, Usman Ghumman, Nikhilesh Anand, Kelsey A. Potter-Baker, Bharathi Gadad

School of Medicine Publications

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by persistent deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interests, or activities. These features are associated with atypical early brain development and connectivity. While ASD has been traditionally associated with molecular genetic alterations, recent research highlights the significant contribution of various environmental factors to the pathophysiology of the disorder. Pathogenic genetic variations in key regulatory genes remain central to ASD risk; however, environmental influences such as advanced maternal or paternal age, poor maternal health during pregnancy, gestational diabetes mellitus, alterations in the early-life …

A Molecular Renaissance In Alzheimer's Disease Research: The Rise Of Systems Biology And Spatial Omics, Lucia M. Perez-Navarro, Juan Lopez-Alvarenga

School of Medicine Publications

Recent advances in multi-omics and spatial proteomics are reshaping our understanding of Alzheimer's disease. Guo et al.1 applied integrative multi-omics to stratify mild cognitive impairment into biologically distinct subtypes with divergent progression trajectories: one metabolically impaired and slow-progressing, the other immune-activated and rapidly declining. Current techniques such as STC-DESI, LCM-MS, and machine learning enhance regional proteomic resolution, supporting biomarker discovery and spatially targeted interventions. This work exemplifies a broader shift toward precision medicine and a systems-level molecular framework in neurodegenerative disease research.

Advocating For Transitional Programs For Adolescents With Idd And Asd, Gabriel D. Moore

Occupational Therapy Doctoral Capstones

This capstone project aimed to empower HIPsters at My Possibilities, a higher education and transitional program located in Plano, TX. Specifically, this project equipped individuals diagnosed with intellectual developmental disability (IDD) and autism spectrum disorder (ASD) with the essential components required to effectively advocate for themselves. Due to the unique challenges this population faces, these components were subjective, allowing for receptivity and class engagement, over the course of 6 weeks. These subjective components developed were Communication, Knowing Yourself, Knowing Your Rights, Goal Making, Initiative, Problem-Solving, Handling Adversity, Managing Emotions, Selflessness, Leadership, and Teamwork. Upon completion of the course, HIPsters reported …

Administration Plan For Use Of Hippotherapy In Occupational Therapy, Ryanna Blake

Occupational Therapy Doctoral Capstones

The intention of this capstone experience was to promote the use of hippotherapy as a treatment strategy in the occupational therapy profession from an administrative and educational standpoint. Hundreds of research studies have indicated the effectiveness of hippotherapy for a variety of ages and diagnoses. However, there are still barriers that prevent hippotherapy from being more accessible and well-known, both by practitioners, client families, and the community. The project was executed at a startup psychotherapy clinic preparing to offer equine-assisted services in Tulsa, Oklahoma. The mutually beneficial partnership led to the creation of a generalized administration plan for an occupational …

Educational Program To Prevent Long-Term Complications For Individuals With Diabetes, Emily M. Ware

Occupational Therapy Doctoral Capstones

This doctoral capstone project aimed to create an educational program to improve quality of life for individuals with diabetes by enhancing daily self-management and occupational engagement to prevent long-term complications. The literature states that although diabetes complications are common, they are also highly preventable through self-management strategies. Because diabetes self-management is deeply embedded into daily routines, occupational therapy practitioners can play a unique role in supporting individuals in this process. Prior to participation in the educational program, participants completed a screening tool assessing their diabetes management routines and confidence in the context of daily activities. An occupational therapy-informed, six-week educational …

Program Development For Previously Incarcerated Individuals Transitioning Back Into Society, Shiean Raychel Walters

Occupational Therapy Doctoral Capstones

This project supports individuals re-entering society after prison, dealing with substance abuse, or court commitments. Through real-life activities such as paying rent, working, cooking, and community service, it helps participants build independence, manage routines, and prevent relapse or recidivism. The program offers occupational therapy-based interventions to address key life skills like time and money management, job acquisition, self-care, and emotional regulation. It also aids in addiction recovery, ensuring individuals can adapt to new roles and routines that may initially feel unfamiliar or uncomfortable. A key component is an occupational therapy assessment that evaluates participants’ readiness to transition to independent living, …

Education And Advocacy For Implementation Of Biofeedback Therapy In Pediatrics With Anxiety And Migraine Headaches, Mckenly Roberts

Occupational Therapy Doctoral Capstones

This capstone project explores the implementation of biofeedback therapy in occupational therapy for treating pediatric migraines and anxiety. A comprehensive literature review was conducted, examining peer-reviewed articles from 2000–2024, which revealed biofeedback therapy’s efficacy in addressing stress-related symptoms across age groups. The study focuses on adolescents’ academic and extracurricular occupations, where stress significantly impacts mental and physical health. The project aims to establish a biofeedback therapy program at the Abilene Christian University Psychology Clinic, addressing gaps in current literature and practice guidelines. Utilizing the Person-Environment-Occupation-Performance (PEOP) model, the research highlights biofeedback’s potential to improve functional performance and participation for children …

Oncology Rehabilitation In Occupational Therapy, Callie D. Freeman

Occupational Therapy Doctoral Capstones

This doctoral capstone project examined the need for occupational therapy (OT) services among individuals diagnosed with cancer and cancer survivors. Evidence indicates that cancer-related fatigue, decreased participation, and diminished quality of life are common challenges following different types of cancer treatment. Occupational therapy addresses these issues through occupation-based interventions, fatigue management education, energy conservation strategies, and activities that promote strength, stability, and social participation. Nevertheless, a gap persists in the utilization of OT services within oncology treatment care. Over a 14-week period, this project implemented group-based interventions to enhance the quality of life and engagement among cancer survivors affiliated with …

Program Development And Administration Of Experiential Learning Practices In Ot Education, Elizabeth Ann Marie Beeman

Occupational Therapy Doctoral Capstones

Experiential learning opportunities enhance occupational therapy students’ clinical skills, confidence, and professional preparation through hands-on practice. This capstone project focused on program development and administration at Abilene Christian University’s occupational therapy department. Initially centered on establishing a student-run campus clinic, the project pivoted during week one when needs assessment revealed the clinic concept no longer aligned with departmental and university strategic goals. The revised focus incorporated experiential learning theory and interprofessional education. Over 14 weeks, I conducted nine faculty interviews and four student focus groups. Findings indicated unanimous support for mandatory, scheduled experiential learning opportunities while identifying common implementation barriers, …

Education Of Trauma-Informed Care In The School System: An Occupational Therapy Perspective, Jada F. Muller

Occupational Therapy Doctoral Capstones

This capstone experience focused on providing education to faculty and staff of elementary-aged children. This includes education about signs of trauma, techniques to use for the classroom, and how occupational therapy can contribute to trauma-informed interventions in the school system. More research is needed to show the implications of trauma informed practice and the role of occupational therapy within the school system. To address this gap, this doctoral project was designed to fulfill the need for trauma-informed education and add to the body of knowledge. This project took place at Denison Independent School District, where I created deliverables addressing different …

Experiences Of U.S. Frontline Physicians During The Covid-19 Pandemic: A Qualitative Study, Robin L. Whitney, Melissa Gosdin, Sabrina F. Loureiro, Marykate Miller, Joy Melnikow, Richard L. Kravitz

Faculty Research, Scholarly, and Creative Activity

Background: The COVID-19 pandemic caused profound and rapid changes in patient care and healthcare system organization. There is a compelling need for insight into the challenges that confronted physicians during the early phase of the pandemic to identify successful adaptations and strategies that minimize disruption to patient care and protect clinician wellbeing. The purpose of this study was to understand physicians’ lived experiences of providing patient care during the early COVID-19 pandemic. Methods: This qualitative, descriptive study used a thematic analysis approach. The sample included 17 physicians from five specialties with direct care experience of COVID-19 patients (infectious disease, primary …

The (Birthweight) Gains From Trade: Chinese Imports And Infant Health In Sub-Saharan Africa, Jorge M. Aguero, Patralekha Ukil

Faculty Research, Scholarly, and Creative Activity

A growing literature has documented broad negative impacts of Chinese imports to advanced economies, mainly due to the competition of these imports with local production. However, for countries with a smaller manufacturing sector and which have not experienced a structural transformation away from agriculture, Chinese imports could have positive effects. We find evidence supporting this claim using a sample of over 350,000 births from 25 countries in Sub-Sahara Africa. Our identification compares the birthweight of biological siblings born at different levels of Chinese imports to their country. We find that an increase in Chinese imports of $100 (constant USD) is …

Principals’ Perceptions Of Their Preparedness To Facilitate And Support Technology Integration In Schools: A Case Study Of Four Rural Texas Principals, Christina J. Campbell Ed.D.

Electronic Theses and Dissertations

School administrators face the challenge of leading technology integration that provides meaningful learning opportunities to prepare students for 21st-century skills and careers. Research has shown that administrative leadership support, behaviors, assumptions, and policies impact technology integration in the classroom. The International Society for Technology in Education (ISTE) standards include guidelines for education leaders and their role in supporting educators using technology. However, leaders underestimate the impact of their leadership on effective use in the classroom. The purpose of this qualitative case study was to explore the perceptions of South Texas rural public school principals working in Chapman Independent School District …

Misodice: Multi-Agent Imitation From Mixed-Quality Demonstrations, The Viet Bui, Tien Mai, Hong Thanh Nguyen

Research Collection School Of Computing and Information Systems

We study offline imitation learning (IL) in cooperative multi-agent settings, where demonstrations have unlabeled mixed quality - containing both expert and suboptimal trajectories. Our proposed solution is structured in two stages: trajectory labeling and multi-agent imitation learning, designed jointly to enable effective learning from heterogeneous, unlabeled data. In the first stage, we combine advances in large language models and preference-based reinforcement learning to construct a progressive labeling pipeline that distinguishes expert-quality trajectories. In the second stage, we introduce MisoDICE, a novel multi-agent IL algorithm that leverages these labels to learn robust policies while addressing the computational complexity of large joint …

Rising From Ashes: Generalized Federated Learning Via Dynamic Parameter Reset, Jiahao Wu, Ming Hu, Yanxin Yang, Xiaofei Xie, Zekai Chen, Chenyu Song, Mingsong Chen

Research Collection School Of Computing and Information Systems

Although Federated Learning (FL) is promising for privacy-preserving collaborative model training, it suffers from low inference performance due to heterogeneous client data. Due to heterogeneous data across clients, FL training easily learns client-specific overfitting features. Existing FL methods adopt coarsegrained averaging, which can easily cause the global model to get stuck in local optima, leading to poor generalization. Specifically, this paper presents a novel FL framework, FedPhoenix, to address this issue. It stochastically resets partial parameters in each round to destroy some features of the global model, guiding FL training to learn multiple generalized features for inference rather than specific …

Stayin’ Alive: Examining The Moderating Effect Of Suicide Resilience On The Relationship Between Sexual Minority Stress And Subjective Well-Being, Natalie A. Sachs

Dissertations

Suicidality among sexual minorities is concerning and results from increased social stress, societal stigma, and experiences of discrimination. The effects of sexual minority stress (SMS) lead to negative outcomes for sexual minority college students. The purpose of the current study was to better understand the role of suicide resilience in moderating the adverse effects of SMS among sexual minority college students. The following research questions and hypotheses guided this study: Q1 Does SMS have any effect on subjective well-being among college-student sexual minority individuals (SMIs)? Q2 Does SMS have any effect on suicide resilience among college student SMIs? Q3 To …

Hypercalcemia Of Down Syndrome., Seth Lmb, Melissa Litao, Nasreen Talib, Jacob M. Redel

Manuscripts, Articles, Book Chapters and Other Papers

We present a case of hypercalcemia in a 12-month-old female with Down syndrome. The patient presented with significant weight loss (810 g since her 6-month visit) and severe growth failure (weight 5.8 kg, -4.5 SDs). Laboratory evaluation revealed severe hypercalcemia with appropriately suppressed PTH and 1,25-hydroxyvitamin D levels. Renal ultrasound confirmed medullary nephrocalcinosis. After excluding common etiologies, the patient was diagnosed with hypercalcemia of Down syndrome, also termed Abnormal Calcium, Calcinosis, Creatinine in Down syndrome. Treatment with intravenous fluids, calcitonin, and transition to a low-calcium formula (Calcilo XD) normalized serum calcium levels. The patient maintained normal calcium levels on restricted …

Categorizing Weight Growth Of Infants Born Before 32 Weeks' Gestation Using The 2023 Postnatal Growth Charts For Preterm Infants., Fu-Sheng Chou, Hung-Wen Yeh, Crystal Hsueh, Jing Zhang, Maria Fe B. Villosis, Karine Barseghyan, Ashwini Lakshmanan, Reese H. Clark

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: To categorize growth and correlate growth categories with morbidities in infants born before 32 weeks of gestation.

STUDY DESIGN: This retrospective study categorized weight growth by correlating mean growth velocity (GV) with growth trajectory z-score changes (ΔGTZ ), as measured using 2023 Postnatal Growth Charts for Preterm Infants. The associations between weight categories and morbidities were assessed.

RESULTS: Weight gain of infants without morbidities was categorized into three groups based on correlating ΔGTZ with mean GV: slower ( ΔGTZ < -0.1), in-parallel ( ΔGTZ -0.1 to 0.3), and faster ( ΔGTZ > 0.3). The proportions of infants with and without morbidities in these categories were evaluated across two distinct cohorts, revealing similar …