Digital Commons Network^™

Occupational Therapy For Sleep Dysfunction: An Education Course For Students And Occupational Therapy Practitioners, Hayley Shank, Mary Smith, Emily Frank

Spring 2022 Virtual OTD Capstone Symposium

Sleep disorders are the second most frequent complaint, after pain, in individuals with chronic illness; the healthcare field is considering this an epidemic. Research suggests there is an insufficient amount of awareness and education regarding treating sleep dysfunction among occupational therapy students and practitioners. The purpose of this capstone project was to create an OT education course for OT students and practitioners to utilize when addressing sleep dysfunction with their clients and caregivers. Results of my course support the capstone problem statement; that there is an insufficient amount of awareness and education regarding the treatment and management of sleep dysfunction …

Scaling Up Context-Tailored Clinical Guidelines And Training To Improve Childbirth Care In Urban, Low-Resource Maternity Units In Tanzania: A Protocol For A Stepped-Wedged Cluster Randomized Trial With Embedded Qualitative And Economic Analyses (The Partoma Scale-Up Study), Nanna Maaløe, Natasha Housseine, Jane Brandt Sørensen, Josephine Obel, Brenda Sequeira Dmello, Monica Lauridsen Kujabi, Haika Osaki, Thomas Wiswa John, Rashid Saleh Khamis, Zainab Suleiman Said Muniro, Daniel Joseph Nkungu, Britt Pinkowski Tersbøl, Flemming Konradsen, Sangeeta Mookherji, Columba Mbekenga, Tarek Meguid, Jos Van Roosmalen, Ib Christian Bygbjerg, Thomas Van Den Akker, Andreas Kryger Jensen, Morten Skovdal, Hussein Kidanto, Dan Wolf Meyrowitsch

Faculty of Health Sciences, East Africa

While facility births are increasing in many low-resource settings, quality of care often does not follow suit; maternal and perinatal mortality and morbidity remain unacceptably high. Therefore, realistic, context-tailored clinical support is crucially needed to assist birth attendants in resource-constrained realities to provide best possible evidence-based and respectful care. Our pilot study in Zanzibar suggested that co-created clinical practice guidelines (CPGs) and low-dose, high-frequency training (PartoMa intervention) were associated with improved childbirth care and survival. We now aim to modify, implement, and evaluate this multi-faceted intervention in five high-volume, urban maternity units in Dar es Salaam, Tanzania (approximately 60,000 births …

Researchers Pioneering Long-Read Sequencing Studies Explain Why Long Reads Matter, Staff

Browse All News

No abstract provided.

Lee's Journey Through Uab Is Marked With "Discovery And Self-Exploration", Staff

Browse All News

No abstract provided.

Communicating Change During A College Merger Process: A Grounded Theory Approach, Jessalyn Sabin

Dissertations, Theses, and Projects

Merger is rapidly becoming an approach to addressing the enrollment and financial challenges posed to higher education in the wake of recent demographic shifts and funding changes in the United States. This study focuses on a district of rural community colleges in a Midwest, unionized state college system that is in the process of merging into a single institution. The main locus of the study is on the communication perspectives of leaders during this merger and the changes that it engendered. Eight leaders were interviewed to examine the following questions: Q1) Which communication strategies do leaders at five different public …

An International Analysis Evaluating Frontline Bendamustine With Rituximab In Extranodal Marginal Zone Lymphoma, Juan Pablo Alderuccio, Marcus P Watkins, Raya Saba, Brad S Kahl, Et Al

Open Access Publications

Extranodal marginal zone lymphoma (EMZL) is a heterogeneous non-Hodgkin lymphoma. No consensus exists regarding the standard-of-care in patients with advanced-stage disease. Current recommendations are largely adapted from follicular lymphoma, for which bendamustine with rituximab (BR) is an established approach. We analyzed the safety and efficacy of frontline BR in EMZL using a large international consortium. We included 237 patients with a median age of 63 years (range, 21-85). Most patients presented with Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1 (n = 228; 96.2%), stage III/IV (n = 179; 75.5%), and intermediate (49.8%) or high (33.3%) Mucosa Associated …

April 12, 2022 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Vollen, Gene, Papers, 1968-1990, Special Collections, Leonard H. Axe Library

Finding Aids

This collection consists of letters, photographs, lectures, programs, audio recordings, and newspapers primarily relating to the life and career of Eric Vaughn.

A native of Michigan, Dr. Gene Vollen (1933-) attended Michigan State University, where he earned degrees in music education and theory/composition. His doctoral studies were completed in 1970 at North Texas State University, focusing on musicology with a minor in composition. Listed among his academic honors is a Fulbright Fellowship to the Sorbonne in 1965-66.

Prior to his appointment at Pittsburg State University (PSU) in 1970, Dr. Vollen taught in the music departments of Union University in Jackson, …

Machine Learning-Based Scoring Models To Predict Hematopoietic Stem Cell Mobilization In Allogeneic Donors, Jingyu Xiang, Min Shi, Mark A Fiala, Feng Gao, Michael P Rettig, Geoffrey L Uy, Mark A Schroeder, Katherine N Weilbaecher, Keith E Stockerl-Goldstein, Shamim Mollah, John F Dipersio

Open Access Publications

Mobilized peripheral blood has become the primary source of hematopoietic stem cells for both autologous and allogeneic stem cell transplantation. Granulocyte colony-stimulating factor (G-CSF) is currently the standard agent used in the allogeneic setting. Despite the high mobilization efficacy in most donors, G-CSF requires 4-5 days of daily administration, and a small percentage of the donors fail to mobilize an optimal number of stem cells necessary for a safe allogeneic stem cell transplant. In this study, we retrospectively reviewed 1361 related allogeneic donors who underwent stem cell mobilization at Washington University. We compared the standard mobilization agent G-CSF with five …

Comprehensive Analysis Of Opioid Use After Common Elective Outpatient Orthopaedic Surgeries, Michael U Okoli, Alexander J. Rondon, Clay B Townsend, Matthew Sherman, Asif M. Ilyas, Rothman Opioid Foundation

Rothman Institute Papers

Background: Prescription opioid abuse remains an ongoing public health crisis, especially in orthopaedic surgery. The purpose of the present study is to analyze opioid-prescribing patterns and investigate risk factors for prolonged opioid use after common outpatient orthopaedic surgical procedures.

Methods: After institutional review board approval, a review of 1,384 patients undergoing common elective outpatient orthopaedic procedures from January 2018 to June 2019 was conducted. Data on controlled substance prescriptions were obtained from the prescription drug monitoring program website. Statistical analysis was done to identify predictors for a second opioid prescription and prolonged opioid use (>6 months).

Results: Over 10% …

Student Senate Meeting Minutes April 12, 2022, Student Senate-Winona State University

Student Senate Meeting Minutes

This document is the official Winona State University Student Senate Minutes April 12, 2022.

Unmasking The Monster: Cathy Ames In John Steinbeck's East Of Eden, Julia N. Parker

Honors College Theses

Critics have considered Cathy Ames, the heinous villain of East of Eden, to be John Steinbeck's most complicated character. Although she is at times truly despicable, readers are prejudiced against her before she is even introduced by the narrator, who couches her entire existence as something monstrous and withholds information that might garner her any sympathy until her literal hour of death. Through a study of both Steinbeck's narrative techniques and his letters to his editor about her, we can see that she may not be as villainous as she is presented to be, but she is most certainly …

Analysis And Identification Of Lipolytic Bacterial Species For The Degradation Of Wastewater Lipids, Lindsay C. Smoak

Honors College Theses

The aim of this study was to isolate native bacterial strains from the wastewater treatment facilities of Statesboro, GA to identify their lipolytic activities. Obtained bacterial strains were further assessed via morphological and biochemical methods to determine their enzymatic capabilities. Use of the detergent Tween-20 in growth mediums was the first criteria to assess lipase activity, and these isolates were further investigated to quantitatively measure lipase presence and activity. Lipase protein was precipitated and dialyzed to perform a lipase activity assay, followed by Sodium Dodecyl Sulphate–Polyacrylamide Gel Electrophoresis (SDS-PAGE) to confirm the presence of the lipolytic enzymes. Sanger sequencing was …

Participants’ Satisfaction With Functional Treatment Goals, Ricki M. Botsford

Honors College Theses

Goal writing is an important part of treatment and helps guide SLPs' plan for their clients. Goals need to be individualized and relevant to the client’s life. One type of goal that focuses on being specific to the client’s life is functional goals, which is based on the ICF. The LPATS is a method for writing functional goals that was developed with the ICF in mind. The student clinician participants were taught to use LPATS with adult aphasia clients and were surveyed and interviewed on the method’s feasibility. The survey scores were recorded and presented in a graph. The interviews …

Between Us: A Short Story Cycle, Kelly C. Wilcox

Honors College Theses

“Between us” is a short story cycle that alternative between the perspectives of two sisters, Skylar and Harmony, and their love interest–Michael. This thesis explores the various ways in which people differently respond to grief and the impacts grief has on lives, relationships, and families. These stories also review the roles race and identity play in the loss of a parent, specifically when the mother is of one race and the father is of another. This thesis contains the first two stories of the longer, in-progress collection.

Mental Health After Injury: How Neighborhoods Impact Recovery, Bryce Hruska, Maria Pacella-Labarbara, Ivan E. Castro, Richard L. George, Douglas L. Delahanty

Population Health Research Brief Series

Each year in the United States, there are over 90 million injury-related emergency department visits, resulting in $4.2 trillion in costs related to medical care, loss of work, and reduced quality of life. Nearly a quarter of injury survivors are diagnosed with a new mental health disorder within the first year of injury. This brief examines several aspects of neighborhood context and their relationship to PTSD symptom severity following an injury. Results show that survivors living in neighborhoods with higher racial segregation and lower socioeconomic status report higher PTSD symptom severity.

Machine Learning Analytics In Real Time For Health Services, Abolfazl Saghafi, Chris P. Tsokos

USF Patents

Methods and systems detect a random state change in a subject in real time. Eye state changes may be identified in encephalogram brain signals, or honeybee dance patterns may be classified. Multivariate signals including state change information are received via a plurality of channels. The signals are sampled and may be filtered to remove DC components. Statistical characteristics of the signals are monitored. When the statistical characteristics exceed a threshold during a critical time interval, a potential change of state is detected. The critical time segment of the signals may be filtered to generate respective state change artifact signals. The …

Association Between Concussions And Suicidality In High School Students In The United States, Grant L. Iverson, Justin E. Karr

Sanders-Brown Center on Aging Faculty Publications

Importance: Prior research has shown a statistically significant association between sustaining a concussion and suicidality in adolescents, but this prior research controlled for relatively few variables predictive of suicidality.

Objective: To examine whether sustaining a concussion remained a significant predictor of suicidality after controlling for relevant covariates (e.g., sexual abuse/assault, bullying, substance use, depression), hypothesizing that the relationship between concussion and suicidality would become non-significant after controlling for these variables.

Design: This study involved secondary data analysis of the 2019 Youth Risk Behavior Surveillance (YRBS) System, a national cross-sectional study of adolescents. Analyses were stratified by gender. …

2022-April-12-Paulus Named Fulbright Scholar, University Marketing And Communication, East Tennessee State University

ETSU News

Dr. Trena Paulus

JOHNSON CITY, Tenn. (April 12, 2022) – Dr. Trena Paulus of East Tennessee State University has been selected as a Fulbright Distinguished Scholar in Humanities and Social Sciences for 2022-23.

Paulus is a professor in the Research Division in the Quillen College of Medicine Department of Family Medicine, director of Undergraduate Research and Creative Activities in the Honors College, and an affiliate faculty member of the Applied Social Research Laboratory at ETSU.

As …

Exploring Popular Music's Affect On Popular Culture Through The Media Format Of A Podcast, Alicia Kobasic

Honors Projects

This project covers the development of a podcast titled "The Podcast" where topics relating to popular music and popular culture and how they affect one another are discussed. The project discusses existing research into the topics as well as the development process of the podcast. It delves into each episode and what was learned through the research into the episode and how the episode was recorded and shared. it also talks about the effectiveness of a podcast as method for delivering research.

Manifestations Of Alzheimer’S Disease Genetic Risk In The Blood Are Evident In A Multiomic Analysis In Healthy Adults Aged 18 To 90, Laura Heath, John C. Earls, Andrew T. Magis, Sergey A. Kornilov, Jennifer C. Lovejoy, Cory C. Funk, Noa Rappaport, Benjamin A. Logsdon, Lara M. Mangravite, Brian W. Kunkle, Eden R. Martin, Adam C. Naj, Nilüfer Ertekin-Taner, Todd E. Golde, Leroy Hood, Nathan D. Price, Erin Abner, David W. Fardo, Linda J. Van Eldik, Alzheimer’S Disease Genetics Consortium

Sanders-Brown Center on Aging Faculty Publications

Genetics play an important role in late-onset Alzheimer’s Disease (AD) etiology and dozens of genetic variants have been implicated in AD risk through large-scale GWAS meta-analyses. However, the precise mechanistic effects of most of these variants have yet to be determined. Deeply phenotyped cohort data can reveal physiological changes associated with genetic risk for AD across an age spectrum that may provide clues to the biology of the disease. We utilized over 2000 high-quality quantitative measurements obtained from blood of 2831 cognitively normal adult clients of a consumer-based scientific wellness company, each with CLIA-certified whole-genome sequencing data. Measurements included: clinical …

Garnet & Black Spring 2022, University Of South Carolina, Office Of Student Media

Garnet & Black Magazine

No abstract provided.

Prostate Cancer Screening Behaviors Among U.S. Immigrants: A Cross-Sectional Analysis Using The Nhis Database, Joshua Linscott, Mathew Hayn, Jesse Sammon, Stephen Ryan

Costas T. Lambrew Research Retreat 2022

Background • The health of immigrants is affected by barriers that challenge all underserved groups, but immigrant-specific factors such as language proficiency and access to physician services are unique and modifiable obstacles that can impede access to quality healthcare. • Immigrants are less likely than the U.S.-born populations to receive screening for breast, cervical, and colorectal cancers. • Patients with limited English proficiency (LEP) are more likely to be diagnosed with advanced stage cancer. • LEP patients with male genitourinary (GU) cancers are 2.58x more likely to be diagnosed at an advanced stage. • Research suggests physicians often do not …

Less Of A Balancing Act And More Of A Juggling Act: How Women Who Work In Student Affairs And Have Children With Disabilities Navigate Their Dual Roles, Kellie Marie Mckinney

Theses and Dissertations

Student affairs professionals often grapple with how to attain proper work/family balance (WFB), as being a part of a helping profession can make it extremely difficult for these professionals to set limits and boundaries. In addition, successfully balancing one's work and family domains appears to be more challenging for parents that have children with disabilities than those with typically developing children. Unfortunately, there is a lack of literature examining how women who work in student affairs and have children with disabilities achieve WFB. As such, the purpose of this general qualitative study is to describe how women who work in …

Development And Implementation Of An Outcome Measure For Move Inclusive Dance, Morgan Sondergeld

OTD Capstone Projects

Due to the need for increased funding at MOVE Inclusive Dance, an outcome measure was created and piloted to display program efficacy. This outcome measure with collected data will illustrate to stakeholders and grant committees the value of MOVE Inclusive Dance. Furthermore, a revised sensory protocol was created to ease student transition from classroom to stage through the use of visuals and strategies. Lastly, an organized document was created for the owner of MOVE Inclusive Dance to continuously apply for grants over the coming years with increased ease.

Genomic Time Machine, Beth Potier

UNH Today Archive

No abstract provided.

Quality Improvement: Improving Type 2 Diabetes Self-Management And A1c Levels In Older Adult Veterans Using An Automated Message System, Danielle Brunson

Dissertations

Background: Diabetes mellitus is prevalent among the US population; particularly type 2 diabetes. As the population ages, the number of adults 65 years of age or older with diabetes is increasing. Diabetes is also common among U.S. veterans. Approximately 25% of U.S. Department of VA patients have diabetes. Evidence demonstrated a prevalence of diabetes among older veterans. Innovative approaches to improve diabetes care and health outcomes for veterans are needed.

Aim: This quality improvement (QI) project examined the use of a unidirectional automated text message system (Annie) to improve self-management behaviors of veterans with Type 2 diabetes, as evidenced by …

The Impact Of Afghan Opium Cultivation On The U.S. Opioid Epidemic, Zachary Wahab Cheek

UNL Student Research Days Posters, Undergraduate

I argue here that increases in Afghan opium cultivation, the most prolific in the world, has depressed American prescription opioid and heroin prices, thereby increasing abuse risk in U.S. addict populations and increasing death rates. Utilizing a two-stage regression model with a sparse dataset from several national and international sources, I find evidence that a one percent increase in Afghan opium production is associated with a 0.122 percent increase in prescription opioid overdose deaths, and a 0.367 percent increase in heroin overdose deaths. Assessing the 2001-2002 Taliban opium ban with an identification strategy, I find that in this timeframe prescription …

Optimal Fludarabine Lymphodepletion Is Associated With Improved Outcomes After Car T-Cell Therapy., Vanessa A. Fabrizio, Jaap Jan Boelens, Audrey Mauguen, Christina Baggott, Snehit Prabhu, Emily Egeler, Sharon Mavroukakis, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Douglas Myers, Nicole A. Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vasant Chinnabhandar, Michael Kunicki, A Yasemin Goksenin, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz, Kevin J. Curran

Manuscripts, Articles, Book Chapters and Other Papers

Chimeric antigen receptor (CAR) T cells provide a therapeutic option in hematologic malignancies. However, treatment failure after initial response approaches 50%. In allogeneic hematopoietic cell transplantation, optimal fludarabine exposure improves immune reconstitution, resulting in lower nonrelapse mortality and increased survival. We hypothesized that optimal fludarabine exposure in lymphodepleting chemotherapy before CAR T-cell therapy would improve outcomes. In a retrospective analysis of patients with relapsed/refractory B-cell acute lymphoblastic leukemia undergoing CAR T-cell (tisagenlecleucel) infusion after cyclophosphamide/fludarabine lymphodepleting chemotherapy, we estimated fludarabine exposure as area under the curve (AUC; mg × h/L) using a validated population pharmacokinetic (PK) model. Fludarabine exposure was …

Effect Of Steam Conditioning On Pecan Safety And Quality And Utilization Of Pecan Shell Extract As An Antimicrobial Coating To Maintain The Quality And Safety Of Fresh Produce, Karuna Kharel

LSU Doctoral Dissertations

Pre- and post-harvest practices can pose microbial risk on fresh produce thus, appropriate intervention strategies to inactivate foodborne pathogens without compromising quality is important. The first part of this study investigated the effect of steam conditioning on inactivating Enterococcus faecium, a surrogate for Salmonella enterica, on in-shell pecans; and second part determined the in vitro and in vivo antimicrobial efficacy of pullulan coating incorporated with pecan shell extract on produce. The treatments’ effect on quality of pecans and produce during storage were also evaluated. In-shell pecans inoculated with Enterococcus faecium (7.28±0.17logCFU/g) were treated with steam at 70°C, 80°C …