Digital Commons Network^™

Preservation Of Autonomy In Pediatric Decision-Making, Crystal Brown

Theses

Pediatric patients must rely on proxy decision-makers, usually a parent or guardian, to make their health care choices for them. There are 3 main frameworks in place for such decision-making. The default is usually that the decision-maker will make the decision that they feel is in the best interest of the child. Limitations on the decision-maker are an aspect often discussed with abuse and neglect at the forefront as thresholds for when limitations and intervention are deemed necessary. Concern for the child’s future autonomy is not made a consideration. Instead, the values and beliefs of the decision-maker are used to …

Usa V. Epolito Estevez-Ulloa

2022 Decisions

USDC for the Eastern District of Pennsylvania

Faculty Senate Agenda, April 25, 2022, Utah State University

Faculty Senate & Faculty Senate Executive Committee

Agenda

• Call to Order- Boyd Edwards, Approval of Minutes, March 28, 2022
• University Business- Noelle Cockett, President | Frank Galey, Provost
• Information- Paul Barr, Education Policies, April 7, 2022
• Reports

Budget and Faculty Welfare Annual Report-Jan Thornton

Committee on Committees Annual Report-Crissa Levin

Calendar Committee Annual Report -Renee Galliher

Recruitment and Retention Annual Report-Heidi

Kesler/Katie Jo North

• Old Business
• New Business

Faculty Code 403 Current | Changes | Final Clean-Scott Hunsaker

Faculty Senate President Elect- Boyd Edwards

Faculty Senate Executive Committee Membership-Boyd Edwards

(College of Engineering – USU Eastern) Format for 2022-2023 Faculty Senate Meetings-John Ferguson

May …

Preclinical Characterization And Target Validation Of The Antimalarial Pantothenamide Mmv693183., Laura E. De Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M J Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering

Natural Sciences and Mathematics | Faculty Scholarship

Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibitor to enter preclinical development. Our studies demonstrate attractive drug-like properties and in vivo efficacy in a humanized mouse model of Plasmodium falciparum infection. The compound shows single digit nanomolar in vitro activity against P. falciparum and P. vivax clinical isolates, and potently blocks P. falciparum transmission to Anopheles mosquitoes. Genetic and biochemical studies identify AcAS as the target of the MMV693183-derived antimetabolite, CoA-MMV693183. Pharmacokinetic-pharmacodynamic modelling predict that a single 30 mg oral dose is sufficient …

Implementing Environmentally Informed Occupational Therapy In Clinical Practice Settings, Chelsea A. Heilbrun

MOT Student Capstones

Anthropogenic environmental decline and associated climate change is causing negative health and wellness and consequently occupational injustices. As human activity continues to be the largest contributing factor to environmental degradation, sustainability practices are essential now more than ever to remediate ecological damages for the health, wellbeing, and occupational justice of current and future generations. Occupational therapy (OT) is an occupation-based profession and therefore implies a focus on human activity with an underlying responsibility to promote environmental sustainability. OT practitioners have a unique ability to support client engagement and participation in ecosystem conservation and sustainability. The purpose of this paper was …

Mainehealth As A Partner In The National Covid Cohort Collaborative (N3c), Susan Santangelo, Kimberly Murray, Kathleen M. Fairfield, John Dipalazzo, Ivette Emery, Cliff Rosen

Costas T. Lambrew Research Retreat 2022

N3C is a secure clinical data analytics platform hosted at the NIH that includes vast amounts of data from a large network of he alth care organizations, including MaineHealth , to accelerate advances in COVID 19 research and clinical care.

Recover: Researching Covid To Enhance Recovery, Theresa Roelke, Anne Breggia, Kathryn Brouillette, Ivette Emery, Lauren Moore, Theresa Roelke, Marc Flore, Jacquieline Lapointe, Abigail Arruda, Lyndsey Gower, Teresa Martel, Darlene Peterson, Clifford Rosen

Costas T. Lambrew Research Retreat 2022

HOW WILL RECOVER ACHIEVE ITS GOALS? NIH has selected health care institutions across the nation, including MaineHealth , to conduct this study, which is anticipated to enroll a total of 15,000 participants who have or had SARS CoV 2 infection and 2,680 control participants without a SARS CoV 2 infection.

Spring 2022 Student Showcase For Research And Creative Inquiry Program, Office Of Student Research

Spring Showcase for Research and Creative Inquiry

No abstract provided.

Development Of Evidence-Based Covid-19 Management Guidelines For Local Context: The Methodological Challenges, Sarah Nadeem, Salima Saleem Aamdani, Bushra Ayub, Nashia Ali Rizvi, Fatima Safi Arslan, Russell Seth Martins, Maria Khan, Syed Faisal Mahmood

Section of Diabetes, Endocrinology and Metabolism

Background: The coronavirus disease 2019 (COVID-19) pandemic has presented as a therapeutic challenge for clinicians worldwide due to its rapid spread along with evolving evidence and understanding of the disease. Internationally, recommendations to guide the management of COVID-19 have been created and updated continuously by the WHO and CDC, which have been locally adapted by different countries. Similarly, Pakistan's National Command Operation Center (NCOC), in its national COVID-19 management strategy, generated guidelines for national implementation. Keeping the guidelines updated has proved challenging globally and locally. Here, we present a summary of the process to assess the evidence, including a time-restricted …

National De-Escalation Training Center: Tools For Law Enforcement To Reduce Unnecessary Use Of Force, Morgan Steele, Tamara Lynn

SACAD: Scholarly Activities

Reducing uses of force is one of the most significant challenges to policymakers and practitioners Of the various methods being proposed, de escalation training represents the option most likely to do so This article reviews the literature concerning uses of force and describes the National De Escalation Training Center ( a decentralized research and training organization recently funded by the Department of Justice, Office of Community Oriented Policing Services With the popular support for de escalation growing in the public consensus, the NDTC answers the call for that training to be evidence based, with the national infrastructure to distribute and …

Effectiveness Of Small-Sided Games In Improving Repeated Sprint Ability In Soccer: A Systematic Review, Matthew Dunn

SACAD: Scholarly Activities

Introduction: Small-sided games (SSGs) for soccer typically use 2-5 players per team on a smaller field. Soccer coaches employ SSGs to simulate specific aspects of full-sized soccer and optimize practice time by working on multiple match components at once. This review was conducted to see if SSGs also improved the physical ability of soccer players, specifically a player’s repeated sprint ability (RSA). Methods: Research databases were searched using specific keywords. Articles were filtered to identify suitable articles for the review. The 4 articles identified were evaluated on participant characteristics, program prescription, load dosage, playing area dimensions, and RSA scores Results: …

Disadvantaged Gifted Students: Latinos, John Carter Jr.

SACAD: Scholarly Activities

This Literature Review examines the underrepresentation of gifted minority students identified in the United States, particularly Latinos. Giftedness and Talent Programs have historically been predominantly white with a diminished minority representation in the case of Latino, Black, and American Indigenous peoples. Although it has been argued in the past, nature vs nurture is not representative of the literature today. The literature shows that underrepresentation is caused by non-inclusive testing and identification bias by teachers. This kind of teacher bias may be caused by overt or implicit prejudice and may affect student interactions and mental health even outside of the gifted …

A Symbolic Transformative Sequential Perinatal Learning Experience, Kathleen R. Ward, Christine L. Hober

SACAD: Scholarly Activities

Leaders in nursing education embrace innovative, real‐world learning environments that transform today's generation of nursing students into critical thinkers. Scheduling exclusive child‐bearing practicums are challenging due to staffing, time, and maternal client presentation (Ardic, et al., 2016). Utilizing Mezirow’s (2000) Transformative Learning Theory, a perinatal continuum of care clinical learning experience evolved. Maternal/infant didactic, high‐fidelity simulation, and real‐world experiences relative to women during the perinatal period afforded an innovative, research supported experience. The aim of this study was to identify the outcomes of students learning through his perinatal experience. Participants (n = 50) consisted of third‐semester baccalaureate nursing students enrolled …

Utilizing Heart Rate As An Exercise Intensity Training Method To Determine Overtraining For Collegiate Long- Distance Runners, Ray Urbina

SACAD: Scholarly Activities

In recent years, heart rate has become easier to measure and collect data. Heart rate is a direct measurement of the autonomic nervous system. Therefore, it is utilized in aerobic training to determine an appropriate exercise intensity within a general population. Long distance runners utilize blood lactate threshold-based and maximum oxygen uptake-based speeds and paces as their exercise intensity during training. Overtraining is often determined by rate of perceived exertion by the athlete. There has yet to be an established physiological marker to indicate overtraining in collegiate long-distance runners. There are strong correlations between blood lactate threshold and VO2 with …

Assessment Climate Survey Of Faculty At Fort Hays State University, April Park

SACAD: Scholarly Activities

Assessment is critical piece in higher education to monitor student learning and program outcomes to ensure institutional effectiveness (Suskie, 2009). Results from rigorous assessment across FHSU support commitment to student academic excellence and student success that align with University strategic plans. Despite the benefits, implementation of assessment has its challenges. Studies suggest institution wide assessment is most effective when assessment culture shows a balanced mix of bottom-up (e.g., through department and program level) and topdown (e.g., institutional expectations) elements (EAU, 2006; Skedsmo & Huber, 2019). FHSU has put much effort to develop a culture of assessment and has noticed a …

The Effects Of Class Iv Laser Therapy In Treatment For Orthopedic Injuries And Disorders: A Systematic Review, Kota Wakasa

SACAD: Scholarly Activities

Introduction: Treatment with laser light energy has been utilized as a modality for pain reduction, modulating inflammation process, and promoting tissue repair for many years. The most recent laser version is called class IV. The purpose of this study was to review the efficacy of class IV lasers on orthopedic injuries and disorders. Methods: Randomized control trial studies using class IV laser treatment were reviewed. The quality of studies was assessed with inclusion and exclusion criteria. Pain reduction, range of motion (ROM), strength, and disability were the main outcomes. Results: 10 articles met inclusion criteria. Improvements in pain ROM, strength, …

Factors Influencing Infant Mortality, Samirah Djachechi

SACAD: Scholarly Activities

In this research project, we aim to understand and explain the variables that are influencing the child mortality rate across various countries. This study is vital because if there is a significant factor in the effect and we can reliably determine infant mortality, more infant mortality can be reduced or prevented. The variables we work with are the child mortality rate as the dependent variable and various independent variables such as the GDP per capita, the number of nurses and midwives, the strength of legal rights index, the immunization measles, the current health expenditure per capita, the population living in …

Guided Reflective Writing Rubric Validation: A Tool For Nursing Education Assessment Of Student Clinical Judgment, Tanya Smith, Shauna Keil

SACAD: Scholarly Activities

Nurse educators have been challenged to not guide clinical judgment development in nursing students but determine students’ level of clinical judgment. As clinical judgment is not easily assessed, nurse educators are seeking reliable measurements of clinical judgment. The researchers of this project sought to determine the reliability and validity of the Guided Reflective Writing rubric as developed by Smith (2020). Students in the Fort Hays State University Nursing program routinely use the Guided Reflective Writing assignment and rubric post-clinical for journaling. Inter-rater reliability was completed on second semester and fourth semester first and last journals. Moderate reliability was established for …

Integrating Geographic And Prehistoric Data To Determine Conservation Needs And Reintroduction Potential For The Guam Kingfisher, Christopher Kingwill

SACAD: Scholarly Activities

Conservation efforts for native birds on the island of Guam are currently being hindered by the invasive brown tree snake (Boiga irregularis) which has decimated the island’s native bird populations. Many of Guam’s endemic bird species, including the Guam kingfisher (Todiramphus cinnamominus), are now extinct and others are critically endangered. A habitat suitability analysis of Guam using physiographic datasets with respect to habitat preferences of the Guam kingfisher was carried out, using raster analysis in ArcMap 10.8.1. Results found suitable habitat that still existed in northern Guam, which correlated to this bird’s previously disjunct geographic range. These potential areas of …

April 20, 2022 Minutes, Swosu Faculty Senate

Faculty Senate Minutes

SWOSU Faculty Senate Minutes

The Impact Of Outcomes On Depression Literacy In School-Age Children Who Received Depression Education, Loretta Q. Smith Aprn, Pnp-Bc, Bobby Bellflower Dnsc, Nnp-Bc, Faanp

Doctor of Nursing Practice Projects

Purpose/Background Recognizing mental illness is crucial in adolescence. It is the second leading cause of suicide and death in children 10-19 years of age. Early identification and recognition of signs and symptoms could prevent progressive mental health illness in early childhood and adulthood. We are seeking to answer the PICO question: In adolescents between 10 and 19 years of age who are enrolled in school (P), how does receiving education on depression awareness (I) compared to not receiving education on depression awareness (C) affect depression scores (O)?

Methods This review was conducted on articles about adolescent children. These articles were …

Sotrovimab: Neutralizing Antibody To Combat Covid-19, Aya Allam, Steven Lippmann

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Urss 2022 Program Booklet, Mary Mcconnell

Undergraduate Research and Scholarship Symposium

No abstract provided.

Impact Of Treatment Length On Individuals With Substance Use Disorders In Allegheny County, Cassie Dibenedetti, Kate Rosello

Undergraduate Research and Scholarship Symposium

Auberle social services is opening the Family Healing Center (FHC), a level 3.5 treatment program in Pittsburgh, PA that provides housing and 24-hour support for families struggling with opioid addiction. We partnered with Auberle to study characteristics of individuals receiving level 3.5 treatment and to determine whether longer treatment lengths correlate with fewer adverse outcomes. We obtained data from the Allegheny County Department of Human Services on 2,016 individuals admitted to level 3.5 treatment in 2019. The data included birth year, race, gender, admittance date, discharge date, and Children Youth and Family (CYF) incidents before and after treatment. We categorized …

Analysis Of Follow-Up Times For Families Discharged From Opioid Addiction Treatment Facilities, Abigail Reith, Carley Reith, Lindsay Moskal, Rachael Neilan

Undergraduate Research and Scholarship Symposium

Caregivers who receive treatment for opioid addiction often face adverse post-discharge incidents involving Children, Youth, and Family (CYF) services. These incidents can be traumatic for the children involved, potentially leading to the removal of a child from their home. Nonprofit social service organizations like Auberle aim to minimize these adverse events by implementing frequent follow-ups with discharged caregivers and their families.

We collaborated with Auberle social services (Pittsburgh, PA) and the Allegheny County Department of Human Services (DHS) to evaluate the effectiveness of standard follow-up times (7, 30, and 90 days post-discharge) in preventing CYF incident and to determine if …

The Next Small Step, Samiya Henry

Undergraduate Research and Scholarship Symposium

As of right now, NASA and other space programs are estimating that by 2026, there will be people living in Space. Whether it be the Moon or Mars, one cannot have a functional society without a proper source of laws, especially since no one country has ownership over space. "One Small Step" will produce this source of laws, called the “Space Bill of Rights,” that will outline important matters like the trade of resources, medical care, government officials, and will ensure the preservation of our physical and figurative footsteps in space. This Space Bill of Rights is made up of …

Discovery Of Sigma-2 Ligands And Prioritization Of Marine Cyanobacteria Extracts For Tnbc Drug Discovery, Katelyn Grenell, Andrea L. Rague, Sahar Mofidi, Jane E. Cavanaugh, Kevin J. Tidgewell

Undergraduate Research and Scholarship Symposium

The role of natural products in drug development is well established. In recent years, marine cyanobacteria have been regarded as a major source of biologically active metabolites with chemical and Figure 5 pharmacological diversity. These cyanobacterial natural products serve as a promising source of drug A. leads for the discovery of therapeutic agents used in the treatment of many diseases of interest, such as CNS disorders, pain, and cancer. We have generated a library of 409 fractions from 37 field collected cyanobacterial samples and screened these fractions against a panel of CNS receptors using radiolabeled ligand competitive-binding assays. Upon analysis …

The Parthenon, April 20, 2022, Tyler Spence, Connor Woodruff, Tyler Kennett, Evan Green, Shauntelle Thompson, Rafael Alfonso, Abby Hanlon, Abby Ayes, Alaina Laster, Isabella Robinson

The Parthenon

No abstract provided.

Oral History Interview With Carol Hernandez, Mona Ramonetti, Victoria Pilato

Racial Unrest of 2020: Experiences from the Stony Brook University Community

Carol Hernandez is a Senior Instructional Designer in the Center for Excellence and Learning and Teaching. The narrator's affiliation with Stony Brook University was true at the time of their interview.

Spring 2022 Longwood Excellence In Research And Creative Inquiry & Incite Award Ceremony Program, Office Of Student Research

Spring Showcase for Research and Creative Inquiry

No abstract provided.