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Articles 29971 - 30000 of 1791766
Full-Text Articles in Entire DC Network
Seroprevalence Of Hbsag Among Healthy Blood Donors In Babylon Governorate, Habbeb S. Naher, Mohammed A., Amil M. Hassan
Seroprevalence Of Hbsag Among Healthy Blood Donors In Babylon Governorate, Habbeb S. Naher, Mohammed A., Amil M. Hassan
Al-Qadisiyah Medical Journal
HBsAg prevalence among healthy blood donors was3% (75:2500). It was increased with age. HBsAg antigenmia was significantly associated with male sex; urban communities; low economic status; low educational level; history of contact with cases of acute hepatitis; but it was not associated with blood group; Rh-type; and a history of blood transfusion.
The Clinical Significance Of Reproductive Hormones Concentration In Follicular Maturation In Patient With Luteal Phase Defect, Buthena Abbas Frhan
The Clinical Significance Of Reproductive Hormones Concentration In Follicular Maturation In Patient With Luteal Phase Defect, Buthena Abbas Frhan
Al-Qadisiyah Medical Journal
Forty infertile female patients were involved in this study. Twenty infertile female were with luteal phase defect and the rest twenty female were with out luteal phase defect they represent control group .All patient were stimulated with clomiphene citrate (clomid) and human menopausal gonadotropin (Humegon). hormones in follicular fluid of mature, intermediet and immature oocytes. 2-To compare the in vitro fertilization rate of the three groups of the oocytes. The luteal phase is characterized by the production of progesterone from the corpus luteum with in the ovary .The corpus luteum is derived both from the granulosa cells that remain after …
Mental Retardation In Children, Causes &Prevention, Zuhair M. Al-Musawi
Mental Retardation In Children, Causes &Prevention, Zuhair M. Al-Musawi
Al-Qadisiyah Medical Journal
This study was conducted to know the definite & probable causes of mental retardation (M.R.) in children & how can we prevent some of the cases. Three hundred eighty three children with moderate to severe (M.R.) were studied in Kerbala Pediatric Hospital over two years from January 2003 to January 2005. The male to female ratio was 1.51:1. The etiology was known in151 patients (39.4%) & was unknown in 232 patients (60.6%). The probable preventable causes include kernicterus, hypoxic ischaemic encephalopathy, severe malnutrition, prematurity neonatal sepsis, hypothyroidism, encephalitis, meningitis, neural tube defect, galactossaemia, shaken baby syndrome & lead poisoning, constituting …
The Evaluation Of Serum Zinc, Copper, Sodium And Potassium Levels In Hemodialysis Patients, Anwar Jasib Th. Al. Mazaal, Yassra A. Mussa
The Evaluation Of Serum Zinc, Copper, Sodium And Potassium Levels In Hemodialysis Patients, Anwar Jasib Th. Al. Mazaal, Yassra A. Mussa
Al-Qadisiyah Medical Journal
The aim of this study was to determine serum zinc(Zn),copper (Cu),sodium (Na) and potassuim (K) levels in patients with chronic renal failure (CRF) undergoning hemodialysis (HD) and to investigate the influnce of HD duration on these trace elements.The study group included (32)HD pateints and a control group of (32) healthy subjects. Blood samples were drown for determination of serum (Zn) and (Cu) levels which measured by atomic absorbtion spectrophotmetry, and serum (Na) and(K) levels measured by electrolyte analyzer. The mean age was (50.5 ±12.7)yr in the (HD) group and (48.1 ± 20.3)yr in the control group .Laboratory findings showed the …
The Relation Between Household Exposure To Passive Smoking And Serum Concentration Of Micronutrient, Buthena Abase Frhan
The Relation Between Household Exposure To Passive Smoking And Serum Concentration Of Micronutrient, Buthena Abase Frhan
Al-Qadisiyah Medical Journal
Twenty female their husband are heavy smokers were involved in this study in addition to another twenty women have no household exposure to cigarette smoking. All women have no serious health problem and they never smoke. The object of our study was to assess the presence of any relation between household exposure to passive smoking and serum concentration of retinol, tocopherols and carotenoids. Persons who smoke cigarettes are known to differ from persons who never smoked with respect to several life style behaviors, including eating less healthful diet and drinking more alcohol. The same could be true, to a lesser …
Discharging Open Mastoid Cavity Contributing Factors & Approach To Managemnt, Adel S. Al- Mayaly, Yasir Lafta Hassoun, Rajaa Jabar Kadhim
Discharging Open Mastoid Cavity Contributing Factors & Approach To Managemnt, Adel S. Al- Mayaly, Yasir Lafta Hassoun, Rajaa Jabar Kadhim
Al-Qadisiyah Medical Journal
Chronic ear discharge is one of the indications of mastoid surgery, however; this persistent discharge may be the outstanding feature of complicated surgery ““Discharging open mastoid cavityâ€. Discharging open mastoid cavity is defined as persistently discharging cavity following canal-wall down mastoidectomy for a period more than 3-6 months.The etiology of this discharging cavity is mutifactorial. This study focuses the light on the contributing factors of the persistence of ear discharge after canal-wall down mastoid surgery: surgical , bacteriological & structural ( Eustachian tube function).Fifty patients with discharging cavity & 40 patients with dry cavity were gathered from the outpatient department …
2024 Facts & Figures, Tennessee. Secretary Of State.
2024 Facts & Figures, Tennessee. Secretary Of State.
Facts & Figures
No abstract provided.
2023 Facts & Figures, Tennessee. Secretary Of State.
2023 Facts & Figures, Tennessee. Secretary Of State.
Facts & Figures
No abstract provided.
Tennessee Blue Book 2025-2026, Tennessee. Secretary Of State.
Tennessee Blue Book 2025-2026, Tennessee. Secretary Of State.
Tennessee Blue Book
No abstract provided.
Tennessee Blue Book 2023-2024, Tennessee. Secretary Of State.
Tennessee Blue Book 2023-2024, Tennessee. Secretary Of State.
Tennessee Blue Book
No abstract provided.
2024 Annual Report Tennessee Nutrient Reduction Task Force, Samuel D. Smith
2024 Annual Report Tennessee Nutrient Reduction Task Force, Samuel D. Smith
Nutrient Strategy Taskforce
No abstract provided.
The Gci Vortex Spine: Integrated Vortex‑Induced Energy Platform Using Arachne V8.7 Smart‑Skin, Resonance‑Adaptive Logic, And Gyroid‑Lattice Structural Core, Michael Victor Caldwell Mr.
The Gci Vortex Spine: Integrated Vortex‑Induced Energy Platform Using Arachne V8.7 Smart‑Skin, Resonance‑Adaptive Logic, And Gyroid‑Lattice Structural Core, Michael Victor Caldwell Mr.
Defensive Publications Series
This disclosure describes the GCI “Vortex Spine,” a modular, solid‑state energy‑harvesting platform designed for long‑duration, low‑maintenance deployment in remote or resource‑limited environments. The system integrates three independently functional inventions: (1) a vortex‑induced vibration (VIV) mechanical tower with electromagnetic generation modules, (2) an adaptive resonance‑control logic engine, and (3) the Arachne v8.7 multi‑modal Smart‑Skin substrate. The mechanical subsystem uses a gyroid‑lattice structural core and helical J‑groove surface geometry to induce controlled vortex shedding at low wind speeds. The logic subsystem uses high‑frequency kinetic sensing and adaptive load modulation to maintain structural safety and optimize power output. The Arachne v8.7 Smart‑Skin provides …
Reengineering Cardiac Rehabilitation For Women: From Access To Equity, Juwairia Alali
Reengineering Cardiac Rehabilitation For Women: From Access To Equity, Juwairia Alali
Saudi Medical Journal
Cardiac rehabilitation (CR) is a corner stone intervention in secondary prevention of cardiovascular disease where a multidisciplinary team provides tailored management of lifestyle interventions, exercise and behavioural counselling. Participating in CR resulted in better rates of tobacco cessation, blood pressure and cholesterol lowering and better glycaemic control [1]. CR participation results in significant lower mortality and hospitalizationand improved quality of life. Despite the body of evidence and the robust recommendation by international guidelines it remains underutilized especially by women.
Bridging The Gender Gap In Cardiovascular Care: A Framework For Women's Heart Care, Julia Grapsa, Ana G Almeida
Bridging The Gender Gap In Cardiovascular Care: A Framework For Women's Heart Care, Julia Grapsa, Ana G Almeida
Saudi Medical Journal
No abstract provided.
Management Of Arrhythmias During Pregnancy In Africa, Mervat Aboulmaaty, Kirellos Mikhail, Bola Sogade
Management Of Arrhythmias During Pregnancy In Africa, Mervat Aboulmaaty, Kirellos Mikhail, Bola Sogade
Saudi Medical Journal
Cardiac arrhythmias represent a significant clinical concern that have been always addressed. Moreover, Pregnancy introduces profound hormonal, autonomic, and hemodynamic changes that add more risk to cardiac patients and increase arrhythmia susceptibility. In our continent, Africa, there is an added risk because of the high prevalence of rheumatic heart disease, peripartum cardiomyopathy, and limited access to healthcare, contributing to adverse maternal and fetal outcomes. This article addresses the epidemics, mechanisms, and management of arrhythmias during pregnancy in African settings, highlighting high-yield real-life cases. We focus on guideline-based management strategies, emphasizing fetal safety, and discuss unique regional challenges, including limited access …
Women’S Cardiovascular Health In 2025: Advancements Achieved, Challenges Ahead, Jamilah S. Alrahimi
Women’S Cardiovascular Health In 2025: Advancements Achieved, Challenges Ahead, Jamilah S. Alrahimi
Saudi Medical Journal
Cardiovascular disease (CVD) is the leading cause of death among women globally. Recognition of sex-specific risk factors, pathophysiology, and clinical presentations has established women's cardiovascular health as a research and clinical priority. Pregnancy complications, premature menopause, and autoimmune disease, are now identified as long-term contributors to cardiovascular risk, while female-predominant syndromes such as ischemia with non-obstructive coronary arteries and heart failure with preserved ejection fraction are increasingly acknowledged. Novel therapies and updated guidelines emphasize psychosocial determinants, reproductive history, and postpartum risk assessment in prevention and management. Despite these advances, women remain underdiagnosed, undertreated, and underrepresented in clinical trials. Diagnostic delays …
Advancing Research For Women’S Cardiovascular Health: A Clinical & Policy Priority Of The Middle East & Mediterranean Women’S Cardiovascular Research Consortium, Mirvat Alasnag
Saudi Medical Journal
No abstract provided.
National Heart Center – Saudi Health Council Acute Myocardial Infarction-Related Cardiogenic Shock Consensus Document, Mirvat Alasnag, Abdulrahman Asiri, Hazim Alrahbi, Nhatem Aloui, Ashraf M Anwar, Saad Alhassani, Maryam Mohamed Alqaseer, Ismail Raid Raslan, Ibrahim Albakri, Ahmed Almustafa, Rowa Attar, Faisal Katbi, Feras Khaleil, Alyaa Elhazmi, Adel Tash, Jehad Alburaiki
National Heart Center – Saudi Health Council Acute Myocardial Infarction-Related Cardiogenic Shock Consensus Document, Mirvat Alasnag, Abdulrahman Asiri, Hazim Alrahbi, Nhatem Aloui, Ashraf M Anwar, Saad Alhassani, Maryam Mohamed Alqaseer, Ismail Raid Raslan, Ibrahim Albakri, Ahmed Almustafa, Rowa Attar, Faisal Katbi, Feras Khaleil, Alyaa Elhazmi, Adel Tash, Jehad Alburaiki
Saudi Medical Journal
Objective: Cardiogenic shock (CS) remains a serious complication of acute myocardial infarction (AMI) with persistently high mortality and significant variability in management across centers. Methods: A multidisciplinary panel convened by the National Heart Center used the GRADE framework to review evidence and develop consensus recommendations tailored to AMI-related CS. Results: The document emphasizes standardized CS definition and staging, prioritizing the SCAI classification. Key components include early recognition, haemodynamic assessment, lactate monitoring, and the central role of echocardiography. Recommendations support rapid culprit-vessel revascularization, early consideration of mechanical circulatory support, and structured Heart Team activation. The document also highlights the need for …
Evaluating The Diagnostic Accuracy Of Ultrasound And Clinical Predictors In Pediatric Acute Tip Appendicitis: A Retrospective Study From A Tertiary Center In Saudi Arabia, Abdullah M. Abu Qarnayn, Saud A. Aljadaan, Suliaman M. Alaqeel, Faisal S. Alshehri, Abdullrzak N. Algosear, Waleed A. Alharthi, Munirah A. Alsukait, Kholoud S Alshaya
Evaluating The Diagnostic Accuracy Of Ultrasound And Clinical Predictors In Pediatric Acute Tip Appendicitis: A Retrospective Study From A Tertiary Center In Saudi Arabia, Abdullah M. Abu Qarnayn, Saud A. Aljadaan, Suliaman M. Alaqeel, Faisal S. Alshehri, Abdullrzak N. Algosear, Waleed A. Alharthi, Munirah A. Alsukait, Kholoud S Alshaya
Saudi Medical Journal
Objective: To examines the diagnostic accuracy of ultrasound (US) and the clinical characteristics of pediatric ATA. Acute tip appendicitis (ATA), a rare form of appendiceal inflammation confined to the distal tip, presents with atypical symptoms and is difficult to diagnose. The Confirmation often relies on imaging and surgical pathology. Methods: A Retrospective cross-sectional study conducted at a tertiary hospital in Riyadh, Saudi Arabia, from 2020 to 2024. Among 4,224 pediatric patients with acute appendicitis under 14 years, and our sample size of 59 patients were diagnosed with ATA by US. Firth logistic regression was used to reduce bias in the …
Risk Factors And Clinical Outcomes Of Abnormal Placental Localization: A Comprehensive Retrospective Analysis, Bessy Varghese, Alia Abdulla Abdullatif, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Khawla Al Sendy, Marwa Abdulrahman Juma Salem, Youstina Georges, Amala Sunder
Risk Factors And Clinical Outcomes Of Abnormal Placental Localization: A Comprehensive Retrospective Analysis, Bessy Varghese, Alia Abdulla Abdullatif, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Khawla Al Sendy, Marwa Abdulrahman Juma Salem, Youstina Georges, Amala Sunder
Saudi Medical Journal
Objectives: To evaluate maternal and neonatal complications associated with various types of placental abnormal localization. Methods: This retrospective study analysed obstetric and neonatal outcomes associated with placental abnormal localization at Bahrain Defence Force Hospital over a 12-month period (January–December 2022). Women were categorized into four groups based on placental localization: placenta previa with accreta, placenta previa with increta, minor previa, and major previa. Maternal demographics, obstetric history, and fetal outcomes were collected. Statistical analysis included Fisher's exact test for categorical variables, the Kruskal-Wallis test for non-parametric variables, and one-way ANOVA for parametric variables. A p-value of Results: A total …
Impact Of Nursing Program Structure On Academic Stress Levels And Self-Concept: A Cross-Sectional Study Of Nursing Students' Experiences With 2- And 3-Semester Academic Calendars, Alaa Ayyadhah Alanazi, Amany Anwar Saeed Alabdullah, Hanan Hamdanalshehri, Abrar M. Almutairi
Impact Of Nursing Program Structure On Academic Stress Levels And Self-Concept: A Cross-Sectional Study Of Nursing Students' Experiences With 2- And 3-Semester Academic Calendars, Alaa Ayyadhah Alanazi, Amany Anwar Saeed Alabdullah, Hanan Hamdanalshehri, Abrar M. Almutairi
Saudi Medical Journal
Objective: To investigate undergraduate nursing students' perceptions of their transition from a 2-semester to a 3-semester academic calendar and examine its impact on academic stress and self-concept. Methods: A cross-sectional study was conducted between April and December 2023 among 185 undergraduate nursing students in Saudi Arabia who had completed at least their foundational year. Participants completed an online questionnaire containing Likert-type scales measuring academic stress and academic self-concept. Data were analyzed using t-tests and ANOVA to explore associations between perceptions and demographic variables. Results: Most students reported low levels of academic stress and maintained a positive academic self-concept. Perceived …
Challenges Of Electronic Medical Record Implementation From The Perspective Of Hospital Leaders In Riyadh, Kingdom Of Saudi Arabia's Public Hospitals: A Mixed-Methods Study, Atheer A. Alghamdi, Samiha H. Sayed
Challenges Of Electronic Medical Record Implementation From The Perspective Of Hospital Leaders In Riyadh, Kingdom Of Saudi Arabia's Public Hospitals: A Mixed-Methods Study, Atheer A. Alghamdi, Samiha H. Sayed
Saudi Medical Journal
Objectives: To assesses the challenges of implementing electronic medical records (EMR) from the leaders' perspective in public hospitals in Riyadh, Kingdom of Saudi Arabia (KSA), and explores their suggestions for improvement. Methods: A concurrent mixed research approach using a purposive sample of all hospital leaders (61) involved in EMR in 5 randomly selected public hospitals utilizing EMR in Riyadh. The researchers deployed a semi-structured interview schedule to collect the data. They used descriptive statistics and ordinal regression analysis for quantitative data, and thematic analysis for qualitative data. Results: Indicate that 80.3% of the hospital leaders had a good perception of …
Investigating The Use Of Antidepressants In Treating Major Depressive Disorder: Insights From A Retrospective Study In Saudi Arabia, Hassan A Alsaad, Wajd A Alfaraj, Maryam M Alrababi, Ali M Sonbaa, Dalal M Albakr, Ali Saleh Abensaad, Fadhel A Alomar
Investigating The Use Of Antidepressants In Treating Major Depressive Disorder: Insights From A Retrospective Study In Saudi Arabia, Hassan A Alsaad, Wajd A Alfaraj, Maryam M Alrababi, Ali M Sonbaa, Dalal M Albakr, Ali Saleh Abensaad, Fadhel A Alomar
Saudi Medical Journal
Objectives: To investigate patterns of antidepressant prescribing and continuation rates among patients with major depressive disorder (MDD) in Saudi Arabia and to identify factors associated with treatment persistence. Method: A retrospective study was conducted at King Fahad Hospital of the University between May 2023 and February 2025. Data on patients' demographic characteristics, diagnostic information, and prescribed medications were collected. Initial antidepressant therapy and treatment continuation were evaluated, and potential influencing factors were analyzed. Results: Selective serotonin reuptake inhibitors (SSRIs) accounted for most first-line prescriptions (71%), followed by SSRI/atypical combinations (11%) and serotonin–norepinephrine reuptake inhibitors (SNRIs) (5%). Of the 220 patients …
Growing Evidence For Distinct Clinical Features And Early Diagnostic Age Of Cutaneous T-Cell Lymphoma In Saudi Arabia: A Retrospective Study In A Tertiary Care Center, Abdulhadi Jfri, Renad Fayez Alharthy, Mariya Yahya Ashqan, Hassan Omar Bogari, Al-Anoud Yousef Alkhashan
Growing Evidence For Distinct Clinical Features And Early Diagnostic Age Of Cutaneous T-Cell Lymphoma In Saudi Arabia: A Retrospective Study In A Tertiary Care Center, Abdulhadi Jfri, Renad Fayez Alharthy, Mariya Yahya Ashqan, Hassan Omar Bogari, Al-Anoud Yousef Alkhashan
Saudi Medical Journal
Objectives: To examine trends in Cutaneous T-cell Lymphoma (CTCL) disease presentation in the Western Region of the Kingdom of Saudi Arabia (KSA). Cutaneous T-cell lymphomas (CTCLs) have heterogeneous clinical presentation, and disease characteristics can vary between regions and ethnic groups. Methods: We conducted a local observational study at the Princess Noorah Oncology Center and King Abdulaziz Medical City, Jeddah, with CTCL patients referred to and treated in the Saudi Arabian National Guard facilities from January 2017 to December 2023. Medical records of included patients were retrospectively reviewed. Main outcome measures were demographics and clinical characteristics. Results: The cohort comprised 69 …
Incidence And Risk Factors For Post-Thyroidectomy Hypocalcemia: A National Study From Saudi Arabia, Saad M. Alqahtani, Bader E. Alsharari, Abdulaziz H. Al-Shahrani, Shehata F. Shehata, Moneer E. Almadani, Yousef S. Alalawi
Incidence And Risk Factors For Post-Thyroidectomy Hypocalcemia: A National Study From Saudi Arabia, Saad M. Alqahtani, Bader E. Alsharari, Abdulaziz H. Al-Shahrani, Shehata F. Shehata, Moneer E. Almadani, Yousef S. Alalawi
Saudi Medical Journal
Objectives: Post-thyroidectomy hypocalcemia is the leading cause of post-thyroidectomy hospitalization, adversely affecting patient quality of life. The current study sought to determine the incidence of post-thyroidectomy hypocalcemia, identify risk factors and their clinical significance, and provide an overview of the incidence in different Saudi Arabian cities. Methods: This retrospective analysis included all patients who underwent thyroidectomies at King Salman Armed Forces Hospital Northwestern Region, Tabuk, Saudi Arabia between 2015 and 2021 and had available pre- and post-operative calcium levels and clinical, surgical, and pathological data. Various risk factors were evaluated using binary logistic regression to determine their impact on the …
Evaluation Of Neutrophil-To-Lymphocyte Ratio And Platelet-To-Lymphocyte Ratio As Biomarkers In Missed Abortions, Ayse Yigit Sonmez, Defne Ay Tuncel
Evaluation Of Neutrophil-To-Lymphocyte Ratio And Platelet-To-Lymphocyte Ratio As Biomarkers In Missed Abortions, Ayse Yigit Sonmez, Defne Ay Tuncel
Saudi Medical Journal
Objectives: To evaluate the usability and clinical significance. Missed abortion, a common complication in early pregnancy. Diagnosis typically relies on ultrasonographic findings and clinical criteria. The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio have attracted considerable interest. Methods: A total of 120 women participated, with 60 diagnosed with missed abortion and 60 with healthy intrauterine pregnancy. This is a retrospective case-control study. Information for the study was gathered from patient file records. Mann-Whitney U Test was used. Logistic regression analysis assessed the magnitude and direction of the relationships between the variables. Results: The youngest participant was 23, while the oldest was 42. …
An Examination Of The Effect On Health Protective Behaviour Of Diabetes And Obesity Awareness And Personal Characteristics In Adults: Structural Equation Modeling, Ayşe Soylu, Pinar Şahin
An Examination Of The Effect On Health Protective Behaviour Of Diabetes And Obesity Awareness And Personal Characteristics In Adults: Structural Equation Modeling, Ayşe Soylu, Pinar Şahin
Saudi Medical Journal
Objectives: The World Health Organization has reported that obesity-related diabetes cases are increasing rapidly. The aim of this study was to examine the effect on health protective behaviour of diabetes and obesity awareness and personal characteristics in adults. Method: This descriptive, cross-sectional, correlational study was conducted with 1241 participants. Data were collected using a Personal Information Form, the Diabetes and Obesity Awareness Scale and Health Protective Behaviour Scale. Data analysis was performed with IBM SPSS vn.23 and IBM AMOS vn.24 software. STROBE was used in reporting. Results: Of the total participants, 45.4% had no diabete and obesity awareness and in …
Clinical Significance Of Ikbkb Mutations: A Focus On Ikbkb-Related Immunodeficiency, Alhomidi Almotiri
Clinical Significance Of Ikbkb Mutations: A Focus On Ikbkb-Related Immunodeficiency, Alhomidi Almotiri
Saudi Medical Journal
Inhibitory kappa B kinase beta (IKBKB, IKK2, or IKKβ ) acts as an activator of the nuclear factor (NF)-κ B signaling cascade that is involved in regulating normal physiological processes and is dysregulated in several pathological processes including immunological disorders. Mutations in IKBKB have been found to cause immune deficiency syndromes. Inherited loss-of-function mutations in IKBKB lead to severe or lethal immune deficiency. In this review, the clinical significance of IKBKB mutations will be reviewed in the context of immune deficiency syndromes. All published clinical cases of IKBKB mutations relevant to immune deficiency, either caused by loss- or gain-of-function mutations …
Brief Geriatric Assessment (Bga): An Evidence-Based Tool For Improving Care Of Older Adults, Assim M. Alabdulkader
Brief Geriatric Assessment (Bga): An Evidence-Based Tool For Improving Care Of Older Adults, Assim M. Alabdulkader
Saudi Medical Journal
The Brief Geriatric Assessment is an approach for rapidly identifying high-risk older adults and guiding timely interventions in busy clinical settings. Unlike the Comprehensive Geriatric Assessment, albeit the gold standard, which is resource-intensive, the Brief Geriatric Assessment offers a scalable alternative by using validated, time-efficient tools to screen for common geriatric syndromes. This narrative state-of-the-art review synthesizes the evidence and best practices regarding the concept, structure, and clinical application of the Brief Geriatric Assessment. It compares the Brief Geriatric Assessment and Comprehensive Geriatric Assessment from theoretical and practical perspectives and outlines how the former can be integrated into healthcare settings, …
Sleep Disorder Phenotypes And The Risk Of Incident Heart Failure: A Meta-Analysis With Mendelian Randomization Validation, Fang Yan, Lihua Fan, Yunhu Chen
Sleep Disorder Phenotypes And The Risk Of Incident Heart Failure: A Meta-Analysis With Mendelian Randomization Validation, Fang Yan, Lihua Fan, Yunhu Chen
Saudi Medical Journal
Objectives: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian randomization (MR). Methods: Fourteen cohorts comprised of participants without HF at baseline were pooled (49,501 exposed; 337,317 controls). A random effects meta-analysis produced pooled hazard ratios (HRs) with 95% confidence intervals (CIs). A bidirectional two-sample MR was used to evaluate the causal effects of sleep phenotypes on HF. Results: Overall, sleep disorders were linked to a higher incidence of HF (pooled HR 1.46; 95% CI 1.30–1.63; pp < 0.001), whereas insomnia was not independently associated with HF (pooled HR 1.11; 95% CI 0.75–1.62; p = 0.609). The …