Digital Commons Network^™

Synthetic Biology Design As A Paradigm Shift Toward Manufacturing Affordable Adeno-Associated Virus Gene Therapies, Logan Thrasher Collins, Selvarangan Ponnazhagan, David T Curiel

2020-Current year OA Pubs

Gene therapy has demonstrated enormous potential for changing how we combat disease. By directly engineering the genetic composition of cells, it provides a broad range of options for improving human health. Adeno-associated viruses (AAVs) represent a leading gene therapy vector and are expected to address a wide range of conditions in the coming decade. Three AAV therapies have already been approved by the FDA to treat Leber's congenital amaurosis, spinal muscular atrophy, and hemophilia B. Yet these therapies cost around $850,000, $2,100,000, and $3,500,000, respectively. Such prices limit the broad applicability of AAV gene therapy and make it inaccessible to …

The Necessity Of Global Standardization Guidelines For Space Travel, Josh Larson, Mallory K. Casebolt

National Training Aircraft Symposium (NTAS)

This study explored the interest in global standardization guidelines for space travel. Due to the lack of accepted minimum international standards and commercialized space travel guidelines, there is a need to explore the feasibility of developing of an agency or clearinghouse for the standardization of certifications, requirements, and ethical standards for space travel between global governments and private entities. This study employed a two-round Delphi design to investigate the need to establish and prioritize such guidelines. The findings yielded from this study provide guidance on how an agency or clearinghouse is needed and could potentially aid in developing such guidelines. …

Developing Critical Thinking And Effective Communication Skills In The Future Aviation Workforce, Cihan Aydiner, Tanya Buhler Corbin, Courtney Tan

National Training Aircraft Symposium (NTAS)

Critical thinking and effective communication are among the top skills necessary for developing a resilient future workforce across professional areas. Recent world events have led to an increase in the demand for these skills in disaster and emergency management professions, especially those in and adjacent to the aviation industry. As such, the importance of higher education settings in teaching the skills needed to equip the workforce to face future challenges cannot be overstated. However, there are gaps in how these skills are taught in higher education to meet the needs of aviation employers seeking disaster and emergency professionals. This paper …

Student Research Opportunities In Aviation Human Factors, Jamie Barrett, Brett Torrence

National Training Aircraft Symposium (NTAS)

When most people think of jobs in aviation or at the Federal Aviation Administration (FAA), they think of pilots, Air Traffic Controllers, Maintainers, etc., those directly involved in the movement of aircraft, passengers, and cargo. However, to safely move over 26K passengers (avg) daily requires many diverse occupations. Included within the complexity of aviation operations are individuals with backgrounds in Psychology, Human Factors, and Instructional Design. It is important to raise awareness of the diversity of aviation jobs and pathways to achieving those opportunities, to attract a diverse next generation workforce. The Human Factors Research Division at the Civil Aerospace …

Lightweight Pairwise Key Distribution Scheme For Iots, Kanwalinderjit Kaur

Journal of Cybersecurity Education, Research and Practice

Embedding a pairwise key distribution approach in IoT systems is challenging as IoT devices have limited resources, such as memory, processing power, and battery life. This paper presents a secure and lightweight approach that is applied to IoT devices that are divided into Voronoi clusters. This proposed algorithm comprises XOR and concatenation operations for interactive authentication between the server and the IoT devices. Predominantly, the authentication is carried out by the server. It is observed that the algorithm is resilient against man-in-the-middle attacks, forward secrecy, Denial of Service (DoS) attacks, and offers mutual authentication. It is also observed that the …

Risk Perceptions About Personal Internet-Of-Things: Research Directions From A Multi-Panel Delphi Study, Paul M. Di Gangi, Barbara A. Wech, Jennifer D. Hamrick, James L. Worrell, Samuel H. Goh

Journal of Cybersecurity Education, Research and Practice

Internet-of-Things (IoT) research has primarily focused on identifying IoT devices' organizational risks with little attention to consumer perceptions about IoT device risks. The purpose of this study is to understand consumer risk perceptions for personal IoT devices and translate these perceptions into guidance for future research directions. We conduct a sequential, mixed-methods study using multi-panel Delphi and thematic analysis techniques to understand consumer risk perceptions. The results identify four themes focused on data exposure and user experiences within IoT devices. Our thematic analysis also identified several emerging risks associated with the evolution of IoT device functionality and its potential positioning …

Cybersecurity Continuity Risks: Lessons Learned From The Covid-19 Pandemic, Tyler Fezzey, John H. Batchelor, Gerald F. Burch, Randall Reid

Journal of Cybersecurity Education, Research and Practice

The scope and breadth of the COVID-19 pandemic were unprecedented. This is especially true for business continuity and the related area of cybersecurity. Historically, business continuity and cybersecurity are viewed and researched as separate fields. This paper synthesizes the two disciplines as one, thus pointing out the need to address both topics simultaneously. This study identifies blind spots experienced by businesses as they navigated through the difficult time of the pandemic by using data collected during the height of the COVID-19 pandemic. One major shortcoming was that most continuity and cybersecurity plans focused on single-axis threats. The COVID-19 pandemic resulted …

Alpha Phi-Shing Fraternity: Phishing Assessment In A Higher Education Institution, Marco Casagrande, Mauro Conti, Monica Fedeli, Eleonora Losiouk

Journal of Cybersecurity Education, Research and Practice

Phishing is a common social engineering attack aimed to steal personal information. Universities attract phishing attacks because: 1) they store employees and students sensitive data, 2) they save confidential documents, 3) their infrastructures often lack security. In this paper, we showcase a phishing assessment at the University of Redacted aimed to identify the people, and the features of such people, that are more susceptible to phishing attacks. We delivered phishing emails to 1.508 subjects in three separate batches, collecting a clickrate equal to 30%, 11% and 13%, respectively. We considered several features (i.e., age, gender, role, working/studying field, email template) …

Dimensionality Assessment Of Fatigue In Collegiate Aviation Operations: A Structural Equation Modeling Approach, Daniel Kwasi Adjekum, Julius Keller, Flavio Antonio Mendonca

National Training Aircraft Symposium (NTAS)

There have been recommendations for evidence-based studies into the safety risk posed by fatigue in the flight training environment from the International Civil Aviation Organization (ICAO), National Transportation Safety Board (NTSB) and the Federal Aviation Administration (FAA). Extant research suggests a paucity of studies on the dimensionality of fatigue in collegiate aviation when compared to scheduled service and military flight operations. As a unique population, collegiate aviation pilots have rigorous course schedules that require intensive studying. Many pilots in this population are active in campus student organization activities and often have part time jobs. These conditions may exacerbate fatigue risks. …

Why Should Airline Workers Be Trained To Respond To Fume Events?, Judith Tl Anderson

National Training Aircraft Symposium (NTAS)

The potential for engine oil and hydraulic fluid fumes to contaminate the ventilation air supplied to the aircraft cabin and flight deck has been recognized since the 1950s as a function of the design and maintenance of the bleed air system. The presence of oil and hydraulic fluid in the bleed air matters because the fumes contain complex mixtures of chemicals, including toxic additives. Starting in the 1950s and continuing to this day, crewmembers around the world have documented ill health during and after breathing these fumes. Also, some crewmembers have reported impairment and even incapacitation inflight, resulting in investigations …

An Aviator Centered Approach To Mental Health: A Preliminary Look At Stressors, Barriers To Care, And Untreated Aviator Mental Health, Aric J. Raus

National Training Aircraft Symposium (NTAS)

The purposeful crash of Germanwings 9525 in March 2015 provided a wake-up call to the aviation community on the ramifications of untreated mental health in commercial aviation. While the airline industry and governmental regulating bodies reacted quickly with peer-support networks and attempts to de-stigmatize seeking assistance, few actions or studies have focused on mental health from an Aviators perspective. This presentation explores the possible stressors impacting aviator mental health among three distinct aviator professional categories: Commercial Aviators, Military Aviators, and Aviators in Civilian Training Programs. After providing an overview of stressors, the discussion transitions into what is known about the …

Mental Health In Pilots Ages 19-26: What Are The New Pilots Telling Us?, Jason T. Lorenzon, Diana Semilia

National Training Aircraft Symposium (NTAS)

Mental Health is stigma that reaches all professional pilots. After spending a considerable amount of money, a pilot is always afraid of losing his/her medical certification. This leads many pilots to not be honest and forthcoming about his/her own health situation or if he/she is forthcoming with any medical deficiency, the regulatory framework at the Federal Aviation Administration may put a further burden on the pilot to provide additional medical documentation, or the FAA may even amend, revoke, or suspend a pilot's medical certificate.

The Federal Aviation Administration (FAA) regulations,14 CFR Parts 61 and 67 and internal protocols creates a …

28 Usc 1916

Civil Matter Files

No abstract provided.

297 F.3d 445, 454

Civil Matter Files

No abstract provided.

316 F.3d 337, 350

Civil Matter Files

No abstract provided.

Black V. Roadway Express

Civil Matter Files

No abstract provided.

Ennega V. Starns

Civil Matter Files

No abstract provided.

National Development And The Sustainability Of Mining In The Atacama Desert, Chile, Dakota Soleil Osgood

Capstone Collection

As climate change continues to intensify on a global scale, efforts have been made to implement renewable energies and progressive technologies. These tools are critical in the shift towards a more sustainable practice, and yet analysis of localized impacts from the development of these mechanisms is inadequate. Chile has been and continues to be a leading country in mineral extraction, with an economic history founded in the mining industry. The establishment of mining in Chile as a progressive tool has aided the social and economic development of the nation. Consequences of mining extraction, however, include intensive environmental degradation, human rights …

The Adaptive Capacity To Implement Climate Migration Policy In Response To Sea-Level Rise In The Maldives, Kelsey Garrett

Capstone Collection

This exploratory study is centered on the increasing harmful impacts of climate change and its connection to human life. The effects are exacerbating the current drivers of migration like livelihoods, security, and politics. People are losing their homes and livelihoods because of drought, rising seas, or increasing natural disasters. Millions of people are. Displaced by climate events every year, the number is expected to increase. Due to this, there is value in studying climate change and migration. Amongst the most vulnerable are those living in Small Island Developing States (SIDS). This exploratory study examined the Maldives to understand their adaptive …

The Belt & Road Initiative, The Impact On Kenya By Way Of The Maritime Route., J Lawrence Englert

Capstone Collection

As China gains power and projects itself across the globe, the struggle to control perception of this new power grows. The majority of current literature regarding Diplomacy and International relations pertaining to the Belt and Road Initiative, specifically the maritime route in Kenya is written from either a Western or a Chinese perspective. The existing literature primarily focuses on the effects of MSR infrastructural projects in Kenya and China’s role not only in Kenya but also in the rest of Africa. This research attempts to better understand the effects of China’s role in Kenya, and if China provides a better …

Imposter Syndrome In Academic Libraries: Indigenous Women Edition, Emilee Bews, Kaia Macleod, Bethany Paul

Urban Library Journal

This is a written proceeding of the LACUNY 2022 panel presentation “Imposter Syndrome in Academic Libraries: Indigenous Women Edition”. The authors discuss personal instances and feelings of the imposter phenomenon (also known as imposter syndrome) as it may relate to their Indigenous identities. Additionally, the authors describe how imposter syndrome may affect their ability to be successful in their careers, and the internal pressure they feel to present a more Indigenous identity (whatever that may entail) for scholarship and positions. The authors also share their experiences with external pressures to exhibit a more “stereotypical Indigenous” appearance for the sake of …

Green Synthesis Of Copper Nanoparticles Using Strawberry Leaves And Study Of Properties, Anti-Cancer Action, And Activity Against Bacteria Isolated From Covid-19 Patients, Arshad Mahdi Hamad, Qanat Mahmood Atiyea, Duaa N. Abdul Hameed, Adil Hussein Dalaf

Karbala International Journal of Modern Science

Severe acute respiratory syndrome type 2 caused by coronavirus 2 is responsible for SARS that led to the emergence of coronavirus disease 2019 (COVID-19). Recent studies have demonstrated a high correlation between secondary bacterial infections and worse outcomes and death in COVID-19 patients. The extensive use of medicines during the last SARS-CoV epidemic led to an increase in the prevalence of multi-drug-resistant germs. Nanoparticles have important characteristics and applications in health, industry, and applied fields, etc. In medical fields, they curb and stop antibiotic-resistant diseases and pathogens. In this study, strawberry leaf extract was used to synthesize copper nanoparticles. The …

2023-01-19_Michiganoverview_Misc, Michigan Department Of Health & Human Services

Michigan COVID-19 MIS-C Data

The MIS-C Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/mis-c-reporting.

This report is created by the Michigan Department of Health & Human Services from data self-reported by health care providers and local health departments. Data is updated on the first and third Thursdays of the month.

Multisystem Inflammatory Syndrome in Children (MIS-C) is a condition in children and adolescents under 21 years of age where multiple organ systems become inflamed or dysfunctional which occurs in association with illness. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, …

Medical School Watercooler Newsletter - January 19, 2023, Lindsey Lyle

Watercooler Newsletter

This is the January 19, 2023 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Researches publish novel findings that could improve management of prostate cancer
• Meet a Med Student: Grace Dunbar
• New members selected for gold humanism in medicine honor society

Static And Dynamic Analysis Of A Bistable Frequency Up-Converter Piezoelectric Energy Harvester, Mohammad Atmeh, Alwathiqbellah Ibrahim, Abdallah Ramini

Mechanical Engineering Faculty Publications and Presentations

Using energy harvesting to convert ambient vibrations efficiently to electrical energy has become a worthy concept in recent years. Nevertheless, the low frequencies of the ambient vibrations cannot be effectively converted to power using traditional harvesters. Therefore, a frequency up-conversion harvester is presented to convert the low-frequency vibrations to high-frequency vibrations utilizing magnetic coupling. The presented harvester consists of a low-frequency beam (LFB) and a high-frequency beam (HFB) with identical tip magnets facing each other at the same polarity. The HFB, fully covered by a piezoelectric strip, is utilized for voltage generation. The dynamic behavior of the system and the …

The Federalists Of The Internet? What Online Platforms Can Learn From Reddit’S Decentralized Content Moderation Scheme, Vincent Marrazzo

Nebraska Law Bulletin (Selected Issues)

As online platforms become the primary carriers of news and information in society, their content moderation policies will have increasing power over users’ daily lives. Centralized moderation is inappropriate and inefficient because it forces all online communities to adhere to the same (and often arbitrary) standards. Decentralized moderation, however, allows most moderation decisions to be made by users who are intimately aware of the contours of individual online communities. Such decisions are less likely to restrict content that is not violative of an online communities’ standards.

This concept of subsidiarity mirrors the arguments made in favor of federalism in which …

Issue 410: January 19-February 2, 2023, The Local Voice

The Local Voice

Townies Favorites 2023

Vol.50 N.26 January 19th 2023, Voice Media Ventures

Black Voice News

No abstract provided.

The Minutes Of The Marshall University Staff Council Meeting, January 2023, Marshall University Staff Council

Staff Council Minutes

No abstract provided.

The Chanticleer, 2023-01-19, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.