Digital Commons Network^™

Long And Short Duration Exposures To The Selective Serotonin Reuptake Inhibitors (Ssris) Fluoxetine, Paroxetine And Sertraline At Environmentally Relevant Concentrations Lead To Adverse Effects On Zebrafish Behaviour And Reproduction, Ananda Baskaran Venkatachalam, Bailey Levesque, John C Achenbach, Jane J Pappas, Lee D Ellis

Faculty, Staff and Student Publications

Selective serotonin reuptake inhibitors (SSRIs) are currently the most prescribed class of psychotropic medications. Their increased global manufacture and use have become growing concerns for aquatic toxicologists and environmental biologists, who assess both the direct and indirect effects of substances on the environment and on human health. In order to assess the potential impact of environmentally relevant levels of SSRIs on fish development, behaviour and reproduction, we exposed juvenile and adult zebrafish to a select group of SSRIs using two separate exposure paradigms. In the first paradigm, juvenile zebrafish were exposed to Fluoxetine (Prozac), Paroxetine (Paxil), Sertraline (Zoloft) or a …

3,3'-Diindolylmethane Augments 5-Fluorouracil-Inducedgrowth Suppression In Gastric Cancer Cells Through Suppression Of The Akt/Gsk-3Β And Wnt/Beta-Catenin, Cong Shan Li, Thi Van Nguyen, Ok Hee Chai, Byung Hyun Park, Ju-Seog Lee, Soo Mi Kim

Faculty, Staff and Student Publications

Gastric cancer (GC) is one of the most lethal cancers in South Korea, and it is a cancer of concern worldwide. 5-fluorouracil (5-Fu) is commonly used as the first-line therapy for advanced GC; however, its side effects often limit the dosage range and impair patients' quality of life. Due to the limitations of current chemotherapy, new anticancer therapies are urgently needed. 3,3'-diindolylmethane (DIM) has been reported to have the ability to protect against various types of cancer. Our study aimed to elucidate the anticancer effect of DIM in GC when treated with the chemotherapeutic agent 5-Fu. In our results, combined …

Factors For Poor Oral Health In Long-Term Childhood Cancer Survivors, Tushar Patni, Chun-Teh Lee, Yimei Li, Sue Kaste, Liang Zhu, Ryan Sun, Melissa M Hudson, Kirsten K Ness, Ana Neumann, Leslie L Robison

Faculty, Staff and Student Publications

Background: Survivors of childhood cancer are at risk for therapy-related dental diseases. The purpose of the study was to investigate the associations between clinical, socioeconomic, and demographic factors and oral diseases in the St. Jude Lifetime Cohort (SJLIFE) participants.

Methods: We performed a retrospective medical chart review and evaluated longitudinal self-reported dental outcomes in 4856 childhood cancer survivors and 591 community controls participating in the St. Jude Lifetime Cohort (SJLIFE) study. Univariate and multivariable logistic regression models were used to assess the impact of socioeconomic factors, treatment exposures and patient demographics on dental outcomes.

Results: Cancer survivors were more likely …

Senior Recital: Medicine, Grace Betzold

Honors Theses

No abstract available.

Mr. Glenn Mosley

African American Funeral Programs

Mr_Glenn_Mosley.pdf - Funeral program for Mr. Glenn Mosley

Preclinical Efficacy Of A Parp-1 Targeted Auger-Emitting Radionuclide In Prostate Cancer, Sreeja Sreekumar, Dong Zhou, Cedric Mpoy, Elsa Schenk, Jalen Scott, Jeffrey M Arbeit, Jinbin Xu, Buck E Rogers

2020-Current year OA Pubs

There is an unmet need for better therapeutic strategies for advanced prostate cancer. Poly (ADP-ribose) polymerase-1 (PARP-1) is a chromatin-binding DNA repair enzyme overexpressed in prostate cancer. This study evaluates whether PARP-1, on account of its proximity to the cell's DNA, would be a good target for delivering high-linear energy transfer Auger radiation to induce lethal DNA damage in prostate cancer cells. We analyzed the correlation between PARP-1 expression and Gleason score in a prostate cancer tissue microarray. A radio-brominated Auger emitting inhibitor ([

Muc1 Expressions And Its Prognostic Values In Us Gastric Cancer Patients, Young-Il Kim, Robert Luke Pecha, Tara Keihanian, Michael Mercado, S Valeria Pena-Munoz, Kailash Lang, George Van Buren, Sadhna Dhingra, Mohamed O Othman

Faculty, Staff and Students Publications

This study aims to evaluate the prognostic value of MUC expression in US GC patients. A total of 70 tumor specimens were collected from GC patients who underwent surgery or endoscopic resection between 2013 and 2019 at a tertiary referral center in the US. MUC expression status including MUC1, MUC2, MUC5AC, and MUC6 was evaluated by immunohistochemical staining. The positive rates of MUC1, MUC2, MUC5AC, and MUC6 were 71.4%, 78.6%, 74.3%, and 33.3%, respectively. Patients with positive MUC1 expression had a significantly higher rate of aggressive pathologic features including diffuse-type cancer (42.0% vs. 0%; p < 0.001), advanced GC (80.0% vs. 30.0%, p < 0.001), lymph node metastasis (62.0% vs. 20.0%; p = 0.001), and …

A Remarkable Treasure Trove Of Recordings, Ken Meltzer

Journal of the Jussi Björling Societies of the USA & UK

A glorious 6-disc (priced as 5) set from Immortal Performances features complete recordings of three Met performances by the brilliant Swedish tenor Jussi Björling, all from his final season at the Met.

Full Issue

Journal of the Jussi Björling Societies of the USA & UK

No abstract provided.

Cedaw Convention And Engendering Faculty Of Law's Curriculum Reinforcement: A Lesson Learnt From Indonesia, Iva Kasuma, Sulistyowati Irianto

Indonesian Journal of International Law

This research aims to describe the strategies used to eliminate discrimination against women through academic-based programs conducted in universities. This includes the International Law, a powerful reference for teaching material in legal education used to promote humanity. Presently, globalization of law is marked in the International Law-making process by delegates from various countries, which spreads to State parties through ratification with a significant impact on legal reform. A number of senior female professors have initiated the socialization and implementation of the Convention on the Elimination of All Forms of Discrimination against Women (CEDAW Convention). This was conducted through the ratification …

Human Relationship With Nature, Indigenous Ways Of Living And Regenerative Tourism Framework, Asif Hussain

Journal of Sustainability and Resilience

In the post Covid-19 era, human civilisation appears to undergo a significant shift in social-ecological consciousness and an emerging concept of ‘regenerative tourism’ is getting popular. The concept acknowledges the strong linkages between humans and nature and together special conditions are created for life to renew and restore itself. While indigenous people have always been aware of their actions and their impacts on the socio- ecological environments, the scientific community has started to acknowledge indigenous knowledge and ways of living. and integrated intelligence. The key aspect of the indigenous lifestyle is the linkages with physical and social environments where humans …

The Blue Zones And The Planet Wellbeing, Emme Vall

Journal of Sustainability and Resilience

This research notes analyses the Blue Zones and its role in future sustainability. Blue Zones are areas of the world where people live longer. The study of their population lifestyles and the dietary patterns is crucial for implementation of policies to increase the wellbeing and the life expectancy of people. There are five areas in the world which are Blue Zones which show a close connection with nature and water, as most of them are located in islands.

The Social Response To Crisis Management In The Jordanian Hotel Sector From The Government Perspective, Mousa Alsheyab, Francesc Fusté-Forné

Journal of Sustainability and Resilience

This paper is part of a major research project that discusses corporate social responsibility practices adopted in Jordan, by hotel managers and other related stakeholders, representing the community and the service providers, during the pandemic crisis. In this paper we focus on the role and measures taken by the government in general, and the Ministry of Tourism and Antiquities in particular, to deal with the Covid-19 pandemic crisis. Amid the Covid-19 outbreak, the hospitality and tourism sectors were challenged and the business policies were adapted. This paper analyzes the measures implemented to secure safety and some tourism expectations as part …

Gauging The Role Of Personality In Risk Perception During A Health Crisis And Its Impact On Tourist Consumption Behaviour, Akshita Agarwal

Journal of Sustainability and Resilience

This study examines the influence of the tourist personality and the use of technology on the traveler behavior and the risk perception about travelling. The purpose of this study is to investigate the link between personality, risk perception, and travel behavior among French travelers. An online survey was conducted using a sample of 422 responses to examine individual variations in risk perception during a health crisis and their influence on travel behavior. The study was carried out using PLS-SEM, and a model was proposed that considered the substantial Average Variance Extracted (AVE) and Composite Reliability test findings. The findings demonstrated …

Film Review: Capernaum, A Lebanese, Refugee Drama Film, Manar Hesino, Manal Al-Natour

Journal of International Women's Studies

In Capernaum, a drama film directed by the Lebanese director Nadine Labaki, the viewer is taken through a child’s perspective on life in the slums of Beirut, Lebanon. Through the perspective of the 12-year-old boy, Zain El Hajj, the film depicts global issues including child poverty, child marriage, the current Syrian refugee crisis, lack of documentation, and gender-based violence.

Gender Responsive Pedagogy Practices: Secondary School Science Teachers In Ethiopia, Mollaw Abrha, Asrat Dagnew Kelkay, Amera Seifu

Journal of International Women's Studies

This paper examines the current status of secondary school science teachers' gender-responsive pedagogy (GRP) practices. Women’s participation in secondary school teaching is a major concern in many regions of the world. The use of instructional strategies that promote gender inclusion and sensitivity in initial teacher training is very important in the development of teachers. In this paper, the use of gender-responsive pedagogy in Ethiopia’s secondary school program is highlighted. Using data from baseline, midterm, and end-line surveys, the paper addresses how tutors and mentors use gender-responsive pedagogy and the changes that have occurred as a result. The study adopted a …

Paradoxes Faced By Women Teachers In Practicing Professional Ethics In Undergraduate Colleges In Nepal, Mamta Sitaula

Journal of International Women's Studies

Women instructors teaching in undergraduate colleges face much unethical behavior during the tenure of their professional lives. The feeling of clashing their professional ethical concerns with institutional misconduct is wisely explained as “experience of professional ethical considerations.” This study adopted a qualitative research design with a humanist research paradigm. I adopted auto/ethnography to study the phenomenon where I myself was a participant in order to relate the feelings of “self” with the other participants. Data saturation was maintained by interviewing five women teachers from different private colleges of Kathmandu Valley, Nepal. The findings were compared and contrasted with various ethical …

Women Suffering From Multiple Sources Of Oppression In Upper Egypt: A Case Study Of Intersectional Targeting And Integrated Development Interventions As The Way Out, Laila El Baradei, Passant Elwy

Journal of International Women's Studies

Scholars in the field of gender and development are strong advocates of the concept of “intersectionality,” first coined by Crenshaw in 1989, as a way of thinking about how marginalized groups may be subjected to oppression from various sources. The main purpose of this research is to make a case for how intersectional targeting, together with integrated development interventions, can be useful in helping vulnerable individuals, specifically women, suffering from multiple sources of poverty and oppression. A case study, coupled with in-depth field interviews, was the method employed for assessing the application of an intersectional lens by a nonprofit development …

Unraveling Milk And Honey: Women’S Voice, Patriarchy, And Sexuality, Renidia Audinia Siva, Ida Rosida, Muhammad Azwar

Journal of International Women's Studies

This article discusses patriarchy and sexuality portrayed in Milk and Honey; a poetry collection written by Canadian author Rupi Kaur. Kaur is an amazing poet, artist, and performer who touches on trauma, feminism, migration, love, and loss in her works. Milk and Honey is a unique book of poetry as it combines written poetry with line art images. The collection is split into four chapters: “the hurting,” “the loving,” “the breaking,” and “the healing.” This research aims to show how the illustrations that appear alongside the poems have amplified the speaker’s voice in response to patriarchy and sexuality. This study …

“Who Hears The Cry Of The Wailing Women?”: Discourses On Livelihood Activities And The Challenges Of Internally Displaced Women In Nigeria, Seun Bamidele, Innocent Pikirayi

Journal of International Women's Studies

In this paper, we examine the livelihoods and daily challenges of internally displaced women (IDW) in the New Kuchingoro Internally Displaced Persons (IDPs) camp in Abuja, Nigeria. We discuss strategies that have the potential to help create successful livelihoods, and we listen to the views of displaced women on how effective they think these strategies might be. We also examine the social and economic factors forcing IDW to develop resilience and highlight the dire social burdens which these women carry with them. Previous studies concerning livelihood activities of IDW in IDPs camps have emphasized distress, hardship, neediness, deprivation, and general …

Now, You Can Breathe: A Qualitative Study Of The Experiences And Resilience Of Egyptian Women Victimized By Narcissistic Relationships, Nayera Mohamed Shousha

Journal of International Women's Studies

Narcissistic relationships manifest as nonreciprocal affiliations that allow no room for genuine partnership or cooperation. The trait of narcissism is more prevalent in men than in women. However, Egypt’s powerful patriarchal culture has prevented adequate scholarly examination of narcissistic relationships. The current study intends to bridge this gap in knowledge by examining two objectives: a) to investigate the nature of experiences of Egyptian women in narcissistic relationships and b) to elucidate how Egyptian women remain resilient in the aftermath of narcissistic relationships. Data were collected via qualitative, semi-structured interviews conducted with 27 literate women aged 24–54 years who had experienced …

Spousal Violence In Karnataka, India: An Analysis Of Nhfs-5 Data, Nabeela Siddiqui, Anwesha Ghosh, Najeed Naved Siddiqui

Journal of International Women's Studies

Spousal violence is a severe public health concern. Despite the expanding scholarship, many concerns remain unresolved about the prevalence of this violence, the risk factors, the repercussions, and how to address the problem. This paper sets out a simple study recognizing the sharp increase of spousal violence in the state of Karnataka, with an overall decrease in the rest of South India. Using India’s National Family Health Survey data, we isolate the effect of spousal violence on female autonomy. The findings have substantial policy implications suggesting that it will take more than an improvement in women’s empowerment options to address …

Gender Politics And Zimbabwe Universities: Facets, Contexts, And Consequences, Efiritha Chauraya

Journal of International Women's Studies

This study explores the perceptions of female middle managers of academic faculties at three universities in Zimbabwe to ascertain their lived experiences, feelings, opinions, and views regarding gender equality in the discharge of their duties. Open-ended, semi-structured, and in-depth interviews were employed for data collection. This method enabled the female deans to describe and reflect on their experiences. Engagement with the female deans of academic faculties revealed that: a) Promotion of women into deanship positions did not translate into eradication of gender-based discrimination against them; b) A lack of a broader vision of gender equality was observed which limited conscious …

Veiled Figures: Attached Settler Women In Andaman’S Post-Colonial Archive, Raka Banerjee

Journal of International Women's Studies

Dominant discourse on India’s eastern Partition (1947) has constructed settlement as a masculine prerogative and man as the settler prototype. Women were eligible for rehabilitation on account of being “attached” to a male guardian, who would be assigned the head of the household in granting state benefits. In the case of these attached settler women transported by the state to Andaman Islands, a range of marginalities–region, gender, caste, and class–intersect with each other to create a veiled figure. The essay locates the settler women in the island’s post-colonial government archive to bring out the state’s construction of gendered settler subjecthood. …

“Am I More Than A Housewife”? An Exploration Of Education, Empowerment, And Gender Preference In Relation To Female Genital Cutting/Mutilation In The Far North Region Of Cameroon, Maurine Ekun Nyok

Journal of International Women's Studies

No abstract provided.

The Heart Is Not Hopeless: Pakistani Television Drama, Patriarchy, And Activism, Neelam Jabeen

Journal of International Women's Studies

A Muslim society that interprets feminism as anti-Islamic may not accept overtly feminist maneuvers to challenge patriarchy. However, there are subtle ways of steering out of the Islam vs. feminism dichotomy. What triggers anti-feminists are phrases like women’s rights, female emancipation, and women’s freedom since all these are interpreted as the agenda of the West and hence are considered anti-Islamic. In this paper, I argue that since feminists are fighting against all forms of oppression and have joined forces with other forms of activism such as child protection, human rights, animal rights, rights of the underclass and minority groups, and …

Dignity, Life-Affirming Advocacy And Compassionate Solidarity, Nyambura J. Njoroge

Journal of International Women's Studies

In “Special Issue: Overcoming Violence against Women and Children” in the Journal of Theology for Southern Africa (No. 114, Nov. 2002), the guest editors Tinyiko Sam Maluleke and Sarojini Nadar wrote:

Given the great cloud and intricate network of witnesses and conspirators who subscribe to the covenant of death, standing up against this covenant of death and violence is costly. It often results in the isolation and rejection of those who dare to speak. Therefore, the voices of those who dare to stand up against the covenant are often like voices in the wilderness (7).

In this essay, I will …

Healing Justice As Intersectional Feminist Praxis: Well-Being Practices For Inclusion And Liberation, Sharon Doetsch-Kidder, Kalia Harris

Journal of International Women's Studies

Since at least the 1830s, Black feminists in the US have spoken of how oppression harms the spirit and have also expressed the need for Black people to respect themselves in the face of anti-Black racism (Guy-Sheftall, 1995). The recognition that oppression negatively impacts well-being continues today. Research in community health and psychology has demonstrated how Black Americans, Native Americans, and Latinx people have been victims of mass incarceration, state-funded and state-sanctioned violence, and systemic discrimination in schools, workplaces, healthcare, and housing. Due to these conditions, racial and ethnic minorities in the US suffer disproportionately from mental and physical illnesses …

Migrant Academic/Sister Outsider: Feminist Solidarity Unsettled And Intersectional Politics Interrogated, Maria Tsouroufli

Journal of International Women's Studies

Feminist sisterhood has been heavily criticized by Black feminists and others as installing a false sense of equality among women and being overly ambitious in disrupting the models and boundaries of the neo-liberal university. This paper draws on the autobiographical account of a White-other, female European migrant academic in the United Kingdom to consider how intersectional disadvantage and privilege shapes feminist sisterhood with profound implications for academic identities, careers, and belonging in the internationalized university and the wider socio-political British context. I draw on my professional trajectory to demonstrate how othering and violence in the form of verbal abuse, microaggressions, …

Editors' Introduction, Kimberly Chabot Davis, Priyanka Tripathi, Catherine Ndinda

Journal of International Women's Studies

No abstract provided.