Digital Commons Network^™

Mcsa Forum Minutes 02/27/2023, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.

Lentz Pediatrics, Plc, Lexington, Tennessee, Tenncare Visits And Payments, January 1, 2017 Through December 31, 2017, Tennessee. Comptroller Of The Treasury.

TennCare Examinations

No abstract provided.

Citizens Of Lake County For Health Care, Inc., Tiptonville, Tennessee, Tenncare Visits And Payments, January 1, 2017, Through December 31, 2021, Tennessee. Comptroller Of The Treasury.

TennCare Examinations

No abstract provided.

Sars-Cov-2 Screening Testing Programs For Safe In-Person Learning In K-12 Schools., Ibukunoluwa C. Kalu, Kanecia O. Zimmerman, Jennifer Goldman, Dana Keener Mast, Ashley M. Blakemore, Ganga Moorthy, Angelique E. Boutzoukas, Melissa M. Campbell, Diya Uthappa, Jesse Delarosa, Jessica M. Potts, Laura J. Edwards, Rangaraj Selvarangan, Daniel K. Benjamin, Tara K. Mann, Jennifer E. Schuster

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) screening testing is a recommended mitigation strategy for schools, although few descriptions of program implementation are available.

METHODS: Kindergarten through 12th grade (K-12) students and staff practicing universal masking during the delta and omicron variant waves from five schools in Durham, North Carolina and eight schools in Kansas City, Missouri participated; Durham's program was structured as a public health initiative facilitated by school staff, and Kansas City's as a research study facilitated by a research team. Tests included school-based rapid antigen or polymerase chain reaction testing, at-home rapid antigen testing, and off-site …

The Free Press Vol. 54, February 02-27-2023, Kelly Ledsworth

Free Press, The

Budgeting: 101--Remembering Arline Saturdayborn--February 10th Student Senate Meeting--Black mental Health Matters--Mardi Gras--The Crack and I--The Call is Coming from Inside the House

Quantitative Analyses Of Interactions Between Spovg And Rna/Dna, Timothy C. Saylor, Christina R. Savage, Andrew C. Krusenstjerna, Nerina Jusufovic, Wolfram R. Zückert, Catherine A. Brissette, Md Motaleb, Paula Schlax, Brian Stevenson

All Faculty Scholarship

The Borrelia burgdorferi SpoVG protein has previously been found to be a DNA- and RNA-binding protein. To aid in the elucidation of ligand motifs, affinities for numerous RNAs, ssDNAs, and dsDNAs were measured and compared. The loci used in the study were spoVG, glpFKD, erpAB, bb0242, flaB, and ospAB, with particular focus on the untranslated 5′ portion of the mRNAs. Performing binding and competition assays yielded that the 5′ end of spoVG mRNA had the highest affinity while the lowest observed affinity was to the 5’ end of flaB mRNA. Mutagenesis studies of spoVG RNA and ssDNA sequences suggested that …

February 27, 2023

The Gavel Gazette

No abstract provided.

Annual Financial Report, Sullivan County, Tennessee For The Year Ended June 30, 2022, Tennessee. Comptroller Of The Treasury.

Tennessee County Audit Reports

No abstract provided.

The Environmental, Social, Governance (Esg) Debate Emerges From The Soil Of Climate Denial, Lawrence J. Trautman, Neal F. Newman

University of Memphis Law Review

No abstract provided.

University Of Northern Iowa Faculty Senate Meeting Agenda, February 27, 2023, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting agenda from the Faculty Senate of the University of Northern Iowa.

Crt-700.34 Short-Term Outcomes Among Aortic Valve Stenosis Patients Undergoing Impella-Supported High-Risk Percutaneous Coronary Intervention, Poonam Velagapudi, Arsalan Abu-Much, Lavanya Bellumkonda, Aneel Maini, Björn Redfors, Alexandra J. Lansky, Yanru Li, Cindy L. Grimes, Wayne B. Batchelor, William W. O'Neill, David J. Cohen

Cardiology Meeting Abstracts

Background: Among patients undergoing percutaneous coronary intervention (PCI), severe aortic stenosis (AS) is associated with an increased risk of adverse outcomes. Although the use of mechanical circulatory support with Impella has been shown to improve 90-day outcomes in patients undergoing high-risk PCI (HRPCI), there is little information about the safety of this approach in pts with severe AS. We, therefore, sought to evaluate the efficacy and safety outcomes of Impella-supported HRPCI among patients with varying severity of AS.

Methods: We studied patients enrolled in PROTECT III—a multicenter study of patients undergoing Impella-supported HRPCI. Patients were classified according to the severity …

Crt-100.12 Risk Of Bleeding Among Cangrelor-Treated Patients Administered Upstream P2y12 Inhibitor Therapy, Jennifer Rymer, Brooke Alhanti, Steven Kemp, Deepak Bhatt, Dominick Angiolillo, Miguel Diaz, Kirk N. Garratt, Ron Waksman, Ajay Kirtane, Lawrence Ang, Richard Bach, Colin Barker, Ronald Jenkins, Mir B. Basir, Alex Sullivan, Hijrah El-Sabae, Leo Brothers, Jeff Washam, Magnus Ohman, Schuyler Jones, Tracy Wang

Cardiology Meeting Abstracts

Introduction: Little is known about the use of cangrelor in patients with MI who are treated with an oral P2Y12 inhibitor upstream prior to cardiac catheterization.

Methods: CAMEO (Cangrelor in Acute MI: Effectiveness and Outcomes) is a 12-hospital observational registry studying platelet inhibition for MI patients undergoing cardiac cath. Upstream oral P2Y12 inhibition was defined as receipt of an oral P2Y12 inhibitor within 24 hours prior to hospitalization or in-hospital prior to cath. Among cangrelor-treated patients, we compared bleeding after cangrelor use through 7 days post-discharge between patients with and w/o upstream oral P2Y12 inhibitor exposure using logistic regression. We …

Crt-700.53 Risk Of Heart Block Development In Surgical Management Of Congenital Heart Disease, Bilal Hussain, Vishal Dhulipala, Ali H. Jafry, Mir B. Basir

Cardiology Meeting Abstracts

Background: There is a paucity of data regarding the risk for heart block during surgical repair of congenital heart disease (CHD). We sought to identify the prevalence and prognosis of heart block in patient’s requiring surgical intervention for CHD.

Methods: National Inpatient Sample 2016-2019 was used to conduct a retrospective analysis by identifying a cohort of patients admitted for surgical management for atrial septal defect repair/replacement (ASDR), ventricular septal defect repair/replacement (VSDR) and patent ductus arteriosus closure (PDAC) using respective ICD-10 codes. Primary outcome was the risk of developing heart blocks including atrioventricular and bundle branch/fascicular blocks which was assessed …

Crt-101.10 Outcomes Of Underlying Infiltrative Cardiomyopathy In Percutaneous Coronary Intervention, Bilal Hussain, Mir B. Basir, Timir Paul

Cardiology Meeting Abstracts

Background: Evidence on the prognosis of infiltrative cardiomyopathy in patients undergoing percutaneous coronary intervention (PCI) has not been well established. Our objective was to assess the prevalence of infiltrative cardiomyopathy including amyloidosis, sarcoidosis and hemochromatosis in PCI patients and its effect on mortality.

Methods: National Inpatient Sample 2016-2019 was used to conduct a retrospective analysis by identifying a cohort of patients who underwent PCI with infiltrative cardiomyopathy using respective ICD-10 codes. Primary outcome was the effect of infiltrative cardiomyopathy on mortality in patients undergoing PCI. Secondary outcomes were the independent predictors of mortality. Multivariate logistic regression model was used for …

Crt-700.66 Principal Diagnosis And Independent Predictors For 30-Day Readmissions In Primary Cardiac Tumor Patients, Bilal Hussain, Mir B. Basir, Ahmed Mahmood, Agastya Belur, Thomas Alexander

Cardiology Meeting Abstracts

Background: Primary cardiac tumors (PCT) are rare with an incidence of 0.3-0.7%. We aimed to study the rate, causes and independent predictors for 30-day readmissions in patients diagnosed with PCT using a national level database.

Methods: We conducted a retrospective cohort analysis using the National Readmissions Database between 2016-2018. ICD-10 codes were used to identify patients with benign and malignant PCT. Patients <18 years and December admissions were excluded. Primary outcomes were the readmission rate and principal diagnosis for 30-day readmissions in patients hospitalized with primary diagnosis of PCT. Multivariate logistic regression was used for analysis.

Results: 4451 patients were admitted with the primary diagnosis of PCT, out of which 4348 patients were discharged alive. Among those discharged alive, 13.8% (599 patients) were readmitted within 30 days. The most common principal diagnosis for 30-day …

Crt-700.1 Multi-Center Compassionate Use Early Feasibility Evaluation Of J-Valve Transcatheter Treatment For Severe Aortic Valve Regurgitation: Preliminary Results, Hanad Bashir, Michael Reardon, Sachin S. Goel, Neil Fam, Julius Jelisejevas, John G. Webb, Jian Ye, Tiberio M. Frisoli, Muhaimen Siddiqui, Santiago Garcia, Geoffrey A. Answini, Dean J. Kereiakes

Cardiology Meeting Abstracts

Background: Although transcatheter aortic valve replacement (TAVR) is accepted therapy for treatment of symptomatic severe aortic valve stenosis (AS), current devices are associated with increased procedural complications and sub-optimal outcomes when used to treat of aortic valve regurgitation (AR). Severe AR is the indication for 20-30% of surgical aortic valve replacements and is associated with increased morbidity and mortality. J-valve is a short frame, self-expanding TAVR device. (Figure) specifically designed for treatment of severe AR. Anchor rings facilitate commissural alignment and secure attachment to non-calcified native valves.

Methods: From Sept 2019 through Oct 2022, patients with symptomatic severe AR who …

Tennessee State Unintentional Drug Overdose Reporting System (Sudors) Report 2023, Tennessee. Department Of Health.

Drug Poisonings and Overdoses in Tennessee

No abstract provided.

Intouch Week Of February 27, 2023, New York Medical College

InTouch

• NYMC and WMCHealth Network Host Sixth Annual HeLa Conference
• Community Read Book Discussion Spotlights the Inequalities in Dental Care
• Harvey: An Educational Tool for NYMC for More Than 20 Years
• NYMC Celebrates National Heart Month
• NYMC Helps 99 Local Patients with Blood Drive Organized by Donate Life Club and New York Blood Center

Ndls Communicator: Week Of 02.27.23, Notre Dame Law School

NDLS Communicator

The Latest News

• Religious Liberty Initiative supports criminal complaint against Chinese government for Uyghur genocide
• The Supreme Court will hear arguments in President Joe Biden’s student loan forgiveness plan case tomorrow. An amicus brief filed by Sam Bray, along with William Baude of the University of Chicago, about the case was mentioned in several media outlets.
• Mary Ellen O'Connell was quoted by Our Sunday Visitor in "Putin’s Suspension Of Key US-Russia Nuclear Arms Treaty Increases Global Risk, Say Experts.”
• Nicole Garnett wrote, "Losing a Lifeline" for the City Journal about the closure of more than a dozen New York City …

Comparing The Efficacy Of Two Inclusivity Interventions On Willingness To Invest In Female- Versus Male-Led Stem And Non-Stem Companies, Alicia Macchione

Dissertations

A notable gender asymmetry has been historically prevalent in science, technology, engineering, and mathematics (STEM) fields. Recent work has shown how gender-inclusive advertisements can increase women’s interest in pursuing these fields as indexed by college course enrollment, which could occur through reminders of moral and pragmatic utilities of gender inclusivity. This dissertation extended prior work by determining if inclusivity priming can be leveraged to facilitate financial investment in hypothetical STEM and non-STEM companies led by either a male or female CEO. Participants were first primed with a statement describing the pragmatic utility of gender inclusivity in STEM, a moral statement …

Transcranial Stimulation For The Treatment Of Stimulant Use Disorder, Amber N. Edinoff, Saveen Sall, T. D. Roberts, Henry H. Tomlinson, Lenise G. Soileau Iii, Eric D. Jackson, Kevin S. Murnane, Danielle M. Wenger, Elyse M. Cornett, Jaime Toms, Deepak Kumbhare, Adam M. Kaye, Alan D. Kaye

Pacific Faculty Work

The increasing prevalence of stimulant use disorder (StUD) involving methamphetamine and cocaine has been a growing healthcare concern in the United States. Cocaine usage is associated with atherosclerosis, systolic and diastolic dysfunction, and arrhythmias. Furthermore, approximately one of every four MIs is cocaine-induced among patients aged 18 to 45. Methamphetamine use has been associated with nerve terminal damage in the dopaminergic system resulting in impaired motor function, cognitive decline, and co-morbid psychiatric disorders. Current treatment options for StUD are extremely limited, and there are currently no FDA-approved pharmacotherapies. Behavioral interventions are considered first-line treatment; however, in a recent meta-analysis comparing …

Use Of Organic Acid Mixtures Containing 2-Hydroxy-4-(Methylthio) Butanoic Acid (Hmtba) To Mitigate Salmonella Enterica, Shiga Toxin-Producing Escherichia Coli (Stec) And Aspergillus Flavus In Pet Food Kibbles, Aiswariya Deliephan, Janak Dhakal, Bhadriraju Subramanyam, Charles G. Aldrich

Department of Food Science and Technology: Faculty Publications

Post-processing operations of extruded pet food kibbles involve coating the product with fats and flavorings. These processes increase the risk for cross-contamination with food-borne pathogens such as Salmonella and Shiga toxin-producing Escherichia coli (STEC), and mycotoxin-producing molds such as Aspergillus spp. after the thermal kill step. In this study, the antimicrobial effects of two types of organic acid mixtures containing 2-hydroxy-4-(methylthio) butanoic acid (HMTBa), Activate DA™ and Activate US WD-MAX™, against Salmonella enterica, STEC and Aspergillus flavus when used as a coating on pet food kibbles were evaluated. Using canola oil and dry dog digest as fat and flavor …

Cultivating A Culture Of Inclusivity In Heliophysics, A. J. Halford, A. G. Burrell, M. W. Liemohn, M. Jones Jr, A. Maute, T. I. Pulkkinen, C. M. Bard, R. M. Mcgranaghan, L. B. Wilson Iii, R. C. Allen, C. Dong, S. K. Vines, L. Wang, Niescja E. Turner, K. Garcia-Sage, K. Mandt, J. Klenzing

Physics and Astronomy Faculty Research

A large number of heliophysicists from across career levels, institution types, and job titles came together to support a poster at Heliophysics 2050 and the position papers for the 2024 Heliophysics decadal survey titled “Cultivating a Culture of Inclusivity in Heliophysics,” “The Importance of Policies: It’s not just a pipeline problem,” and “Mentorship within Heliophysics.” While writing these position papers, the number of people who privately shared disturbing stories and experiences of bullying and harassment was shocking. The number of people who privately expressed how burned out they were was staggering. The number of people who privately spoke about how …

Analysis Of Acquired Resistance Mechanisms To Osimertinib In Patients With Egfr-Mutated Advanced Non-Small Cell Lung Cancer From The Aura3 Trial, Juliann Chmielecki, Tony Mok, Yi-Long Wu, Ji-Youn Han, Myung-Ju Ahn, Suresh S Ramalingam, Thomas John, Isamu Okamoto, James Chih-Hsin Yang, Frances A Shepherd, Krishna C Bulusu, Gianluca Laus, Barbara Collins, J Carl Barrett, Ryan J Hartmaier, Vassiliki Papadimitrakopoulou

Faculty, Staff and Student Publications

Osimertinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), potently and selectively inhibits EGFR-TKI-sensitizing and EGFR T790M resistance mutations. This analysis evaluates acquired resistance mechanisms to second-line osimertinib (n = 78) in patients with EGFR T790M advanced non-small cell lung cancer (NSCLC) from AURA3 (NCT02151981), a randomized phase 3 study comparing osimertinib with chemotherapy. Plasma samples collected at baseline and disease progression/treatment discontinuation are analyzed using next-generation sequencing. Half (50%) of patients have undetectable plasma EGFR T790M at disease progression and/or treatment discontinuation. Fifteen patients (19%) have >1 resistance-related genomic alteration; MET amplification (14/78, 18%) and EGFR C797X mutation …

Molecular Research In Pancreatic Cancer: Small Molecule Inhibitors, Their Mechanistic Pathways And Beyond, Shaila A. Shetu, Nneoma James, Gildardo Rivera-Sanchez, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Pancreatic enzymes assist metabolic digestion, and hormones like insulin and glucagon play a critical role in maintaining our blood sugar levels. A malignant pancreas is incapable of doing its regular functions, which results in a health catastrophe. To date, there is no effective biomarker to detect early-stage pancreatic cancer, which makes pancreatic cancer the cancer with the highest mortality rate of all cancer types. Primarily, mutations of the KRAS, CDKN2A, TP53, and SMAD4 genes are responsible for pancreatic cancer, of which mutations of the KRAS gene are present in more than 80% of pancreatic cancer cases. Accordingly, there is a …

Mmu: 02/27/23–03/05/23, Student Bar Association

Monday Morning Update

This Week @ NDLS

Mass Times

Commons Daily Menu

General Announcements

1L of the Week: Emily McLane

Ask a 3L: Clayton Goldman

Sport Report by Stephen Nugent

Jackie's Corner

Shot Talk: Development And Pilot Test Of A Theory Of Planned Behavior Campaign To Combat College Student Covid-19 Vaccine Hesitancy, Hannah Ball, Tayah Renea Wozniak, Cailin M. Kuchenbecker

Communication Faculty Articles and Research

Among college students, evidence of relatively lower levels of concern of COVID-19 infection, rapid rates of transmission, and lagging vaccination rates substantiates a need to combat college student COVID-19 vaccine hesitancy. This two-phase study comprised formative research, development, and pilot testing of a campaign to combat COVID-19 vaccine hesitancy among college students. In phase one, focus group discussions with college students (N = 48) uncovered their specific attitudes, subjective norms, and perceived behavioral control toward the COVID-19 vaccine. Thematic analysis revealed concerns about vaccine safety, efficacy, cost, and politicization, as well as perceived barriers to accessing information and the …

Neural Responses To Biological Motion Distinguish Autistic And Schizotypal Traits, Matthew Hudson, Severi Santavirta, Vesa Putkinen, Kerttu Seppälä, Lihua Sun, Tomi Karjalainen, Henry K. Karlsson, Jussi Hirvonen, Lauri Nummenmaa

School of Psychology

Difficulties in social interactions characterize both autism and schizophrenia, and are correlated in the neurotypical population. It is unknown whether this represents a shared etiology or superficial phenotypic overlap. Both conditions exhibit atypical neural activity in response to the perception of social stimuli and decreased neural synchronization between individuals. This study investigated if neural activity and neural synchronization associated with biological motion perception are differentially associated with autistic and schizotypal traits in the neurotypical population. Participants viewed naturalistic social interactions whilst hemodynamic brain activity was measured with fMRI, which was modelled against a continuous measure of the extent of biological …

Final Butte Priority Soils Operable Unit, 2021 Unreclaimed Sites Sampling Ur-33 Site Evaluation Summary Report (February 7, 2023), Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Developing Scholar Activists: The Role Of The Edd, Valerie A. Storey, Roschanda Fletcher

All Faculty and Staff Scholarship

A qualitative descriptive approach was followed in the research, starting with a theoretical conceptualization of scholar activism within doctoral education as a basis for further inquiry. Seventeen doctoral candidates described how they conceptualized and applied the Carnegie Project on the Education Doctorate's (CPED) Framework for the Emerging EdD Activist to their experiences in an online program. Study respondents gave accounts of growing confidence to engage in active, vocal advocacy, which they attributed to their new knowledge and understandings gained through participation in the program. However, for some mid-career students, increased vocal advocacy in the workplace was perceived as endangering career …