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Hubungan Pendidikan Ibu Dengan Penggunaan Alat Kontrasepsi Di Desa Wringinsongo Kecamatan Tumpang Kabupaten Malang, Singgih Susilo, Budijanto Budijanto, Ifan Deffinika Jul 2024

Hubungan Pendidikan Ibu Dengan Penggunaan Alat Kontrasepsi Di Desa Wringinsongo Kecamatan Tumpang Kabupaten Malang, Singgih Susilo, Budijanto Budijanto, Ifan Deffinika

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Tujuan penelitian ini adalah untuk menganalisis hubungan antara tingkat pendidikan ibu dan pemakaian alat kontrasepsi dengan kondisi fertilitas di Desa Wringinsongo, Kecamatan Tumpang. Penelitian ini menggunakan pendekatan kuantitatif dengan sumber data utama berupa data primer yang didukung oleh data sekunder. Data primer dikumpulkan melalui observasi lapangan dan wawancara terstruktur mencakup informasi mengenai tingkat pendidikan responden dan partisipasi responden dalam penggunaan alat kontrasepsi. Data sekunder dalam penelitian ini seperti publikasi BPS dan juga penelitian-penelitian terdahulu. Lokasi penelitian dilakukan di Kampung Keluarga Berkualitas (KB) Klasifikasi Mandiri Desa Wringinsongo yang dibentuk oleh Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN). Penelitian ini menggunakan konsep …


Identifikasi Karakteristik Akuifer Dan Potensi Air Tanah Dengan Metode Geolistrik Konfigurasi Schlumberger Di Desa Arjosari, Kecamatan Kalipare, Kabupaten Malan, Listyo Yudha Irawan, Dicky Arinta, Damar Panoto, Irfan Helmi Pradana, Rizal Sulaiman, Estrayudha Nurrizqi, Ravinesh Rohit Prasad Jul 2024

Identifikasi Karakteristik Akuifer Dan Potensi Air Tanah Dengan Metode Geolistrik Konfigurasi Schlumberger Di Desa Arjosari, Kecamatan Kalipare, Kabupaten Malan, Listyo Yudha Irawan, Dicky Arinta, Damar Panoto, Irfan Helmi Pradana, Rizal Sulaiman, Estrayudha Nurrizqi, Ravinesh Rohit Prasad

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Identifikasi potensi airtanah melalui karakteristik perlapisan akuifer merupakan suatu kajian yang penting. Hal ini bermanfaat untuk mengetahui ketersediaan air tanah dangkal di suatu wilayah. Desa Arjosari, Kecamatan Kalipare, Kabupaten Malang merupakan wilayah yang sering mengalami kekurangan air dalam pemenuhan kebutuhan sehari-hari khususnya saat musim kemarau. Kondisi topografi wilayah yang bervariasi dari datar hingga sangat curam merupakan faktor yang mempengaruhi keterdapatan airtanah di lokasi penelitian. Penelitian ini bertujuan mengidentifikasi lokasi keberadaan akuifer dan potensi airtanah di Desa Arjosari. Penelitian ini menggunakan konfigurasi Schlumberger untuk mengidentifikasi akuifer dan airtanah. Metode ini berdasarkan prinsip dasar bahwa masing-masing perlapisan batuan mempunyai nilai tahanan jenis …


Pemetaan Terumbu Karang Dengan Citra Satelit Sentinel-2 Dan Analisis Kondisi Karang Di Kawasan Pantai Pasir Putih, Situbondo Jawa Timur, M. Arif Zainul Fuad, M. Fadilah Nur Ramadhani, Citra Satrya U. Dewi, M. Anwar Fikri, Edo Bagus Herdikusuma Jul 2024

Pemetaan Terumbu Karang Dengan Citra Satelit Sentinel-2 Dan Analisis Kondisi Karang Di Kawasan Pantai Pasir Putih, Situbondo Jawa Timur, M. Arif Zainul Fuad, M. Fadilah Nur Ramadhani, Citra Satrya U. Dewi, M. Anwar Fikri, Edo Bagus Herdikusuma

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Penelitian ini dilakukan di Pasir Putih kabupaten Situbondo, Jawa Timur dengan tujuan untuk memetakan ekosistem terumbu karang dan menganalisis kondisi keanekaragaman karang guna mendukung pembelajaran Geografi pada matakuliah penginderaan jauh. Peta terumbu karang di ekstraksi dari Citra satelit Sentinel-2 dengan menerapkan algoritma koreksi kolom air. Pemetaan area terumbu karang menghasilkan 3 kategori yaitu karang hidup dengan luas 32.860 Ha, karang mati 31.690 Ha, dan pasir 42.670 Ha dengan tingkat sebesar 72,2 persen yang termasuk dalam kategori baik. Pengujian akurasi peta hasil ekstraksi ini menggunakan metode confusion matrix berdasarkan 90 data survei lapangan. Akurasi peta yang dihasilkan ini telah memenuhi standar …


Pembelajaran Outdoor Study Dalam Mata Pelajaran Geografi: Systematic Review, Siti Azizah Susilawati, Salma Lutfiani Sochiba Jul 2024

Pembelajaran Outdoor Study Dalam Mata Pelajaran Geografi: Systematic Review, Siti Azizah Susilawati, Salma Lutfiani Sochiba

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Pembelajaran Geografi kurang efektif jika dilakukan di dalam kelas sehingga membutuhkan strategi pembelajaran. Strategi outdoor study merupakan suatu strategi pembelajaran dimana kegiatan belajar mengajar dilakukan diluar kelas. Penelitian systematic review ini bertujuan untuk mengidentifikasi pembelajaran outdoor study dalam mata pelajaran Geografi di SMA. Penelitian ini merupakan penelitian kualitatif dengan metode systematic review. Desain penelitian ini menggunakan analisis naratif. Hasil penelitian pembelajaran outdoor study dalam mata pelajaran Geografi di jenjang SMA banyak diterapkan pada materi lingkungan hidup dan pembangunan berkelanjutan diperoleh 7 jurnal (29 persen), dan berdasarkan variabel hasil penelitian yang diukur terkait outdoor study yaitu hasil belajar diperoleh 19 jurnal …


Dinamika Hidrokimia Air Tanah Pada Akuifer Pasiran Pulau Yeben Raja Ampat, Papua Barat, Septian Vienastra, Erik Febriarta Jul 2024

Dinamika Hidrokimia Air Tanah Pada Akuifer Pasiran Pulau Yeben Raja Ampat, Papua Barat, Septian Vienastra, Erik Febriarta

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Kualitas air tanah pesisir di pulau kecil memiliki karakteristik yang dipengaruhi oleh faktor lingkungan dan luasan. Pulau Yeben merupakan pulau kecil dengan luas 1,3 km2 dengan prioritas kawasan pariwisata pesisir dan bahari di kepulauan Raja Ampat. Penelitian ini bertujuan untuk (1) menganalisis kadar parameter kualitas air tanah dan (2) menganalisis sampel air terhadap baku mutu air. Sampel air tanah yang diambil sejumlah 4 sampel dari lokasi kajian. Lokasi sampel air berada pada morfologi dataran pantai. Analisis setiap parameter fisik dan kimia masing-masing sampel air tanah dilakukan dengan perbandingan nilai standar baku mutu air minum Hasil penelitian disajikan dalam tabel perbandingan …


Potensi Laboratorium Alam Sumbermanjing Wetan Dalam Pembelajaran Geografi Berbasis Kerja Lapangan (Fieldwork), Alfi Sahrina, Ifan Deffinika Jul 2024

Potensi Laboratorium Alam Sumbermanjing Wetan Dalam Pembelajaran Geografi Berbasis Kerja Lapangan (Fieldwork), Alfi Sahrina, Ifan Deffinika

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Penelitian ini merupakan penelitian deskriptif kualitatif yang menggunakan data sekunder sebagai data utama. Data dikumpulkan melalui studi literatur dari hasil penelitian terdahulu di Kecamatan Sumbermanjing Wetan. Hasil penelitian menunjukkan bahwa Sumbermanjing Wetan memiliki potensi untuk dijadikan sebagai laboratorium alam dalam konteks pembelajaran geografi. Hal ini didukung oleh kondisi fisik berupa kenampakan bentang alam yang beragam, kondisi sosial dan budaya yang cukup kompleks. Potensi tersebut berupa kondisi geologi dan geomorfologi Sumbermanjing Wetan, geodiversitas dan biodiversitas Pulau Sempu, kondisi sosial dan budaya, serta pariwisata. Selain itu, keberadaan sumber daya alam yang ada di daerah tersebut juga dapat digunakan sebagai kajian dalam melakukan …


Faktor-Faktor Kesiapsiagaan Bencana Terintegrasi Pengetahuan Prekursor Gempa Bumi Pada Mahasiswa Pendidikan Ipa, Muhyiatul Fadilah, Enok Maryani, Riandi Riandi, Anna Permanasari Jul 2024

Faktor-Faktor Kesiapsiagaan Bencana Terintegrasi Pengetahuan Prekursor Gempa Bumi Pada Mahasiswa Pendidikan Ipa, Muhyiatul Fadilah, Enok Maryani, Riandi Riandi, Anna Permanasari

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Kesiapsiagaan merupakan kompetensi utama yang harus dimiliki oleh masyarakat rawan bencana, termasuk pada mahasiswa. Kesiapsiagaan dibangun oleh pengetahuan. Penelitian terdahulu menunjukkan level kesiapsiagaan mahasiswa sangat bervariasi, namun belum terdapat penjelasan tentang hubungan pengetahuan dan faktor-faktor lain yang memengaruhi kesiapsiagaan mahasiswa. Selain itu, pengukuran kesiapsiagaan belum mengkaji komponen penanda bencana atau prekursor. Penelitian ini dilakukan untuk mendeskripsikan faktor-faktor yang berhubungan dengan level kesiapsiagaan mahasiswa. Populasi penelitian adalah mahasiwa pendidikan IPA dan penentuan sampel penelitian dilakukan secara purposive, sehingga sebanyak 104 mahasiwa pendidikan IPA yang mengambil matakuliah IPBA ditetapkan sebagai sampel. Penelitian merupakan penelitian deksriptif. Pengumpulan data dilakukan melalui angket kesiapsiagaan TPPG …


Analisis Peringkat Lokasi Potensial Taman Kota Depok Di Tingkat Kecamatan Menggunakan Sistem Informasi Geografis Dan Topsis, Revi Hernina, Yusuf Abdurrohim, Arif Wicaksono Jul 2024

Analisis Peringkat Lokasi Potensial Taman Kota Depok Di Tingkat Kecamatan Menggunakan Sistem Informasi Geografis Dan Topsis, Revi Hernina, Yusuf Abdurrohim, Arif Wicaksono

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Artikel ini menyajikan alternatif peringkat dari 113 lokasi potensial taman Kota Depok di tingkat kecamatan. Lokasi potensial ini dipilih karena memiliki luas ≥24.000 m2 dan <144.000 m2 berdasarkan klasifikasi taman kecamatan. Tiga kriteria spasial berbentuk data vektor, yaitu panjang jalan, wilayah potensial ruang terbuka hijau (RTH), dan luas lokasi diproses dengan Sistem Informasi Geografis (SIG) kemudian diberi bobot menggunakan metode peringkat. Dalam setiap kolom atribut spasial, 3 kriteria tersebut diproses dengan metode Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS) untuk menghasilkan solusi ideal positif (r+) and ideal negatif (r -). Nilai solusi ini dikomputasi menjadi nilai relative closeness (ci+) untuk setiap lokasi taman. Kriteria panjang jalan dan wilayah RTH potensial diklasifikasikan sebagai benefit indices sedangkan luas lokasi taman sebagai cost indices. Hasil studi ini menunjukkan bahwa lokasi taman kecamatan potensial dengan peringkat pertama memiliki nilai ci+ 0,83, sementara peringkat terakhir memiliki nilai ci+ 0,039. Untuk menganalisis kinerja lokasi taman potensial yang dihasilkan TOPSIS terhadap target kebutuhan taman, maka dilakukan prediksi kebutuhan jumlah unit dan luas taman kecamatan berdasarkan proyeksi penduduk tahun 2030 dan 2040. Selanjutnya simulasi prosentase pembangunan taman kecamatan hasil metode TOPSIS diklasifikasi menjadi 3 skenario yaitu skenario I (100%), skenario II (50%), dan skenario III (10%). Dapat disimpulkan untuk penerapan skenario I, hasil studi ini diprediksikan mampu melayani kebutuhan luas taman kecamatan di Kota Depok sampai tahun 2040. Sedangkan untuk memenuhi kebutuhan unit taman kecamatan sampai tahun 2040, skenario I masih bisa diaplikasikan pada 8 kecamatan atau 72,72% dari seluruh kecamatan di Kota Depok.


Environmental Awareness And Pro-Environmental Behavior: A Case Of University Students In Malang City, Ramadhani Lausi Mkumbachi, I Komang Astina, Budi Handoyo Jul 2024

Environmental Awareness And Pro-Environmental Behavior: A Case Of University Students In Malang City, Ramadhani Lausi Mkumbachi, I Komang Astina, Budi Handoyo

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Mahasiswa menunjukkan komitmen yang rendah terhadap perilaku prolingkungan meskipun mereka tahu banyak tentang masalah lingkungan. Tujuan dari penelitian ini adalah (1) untuk mengetahui tingkat kesadaran lingkungan dan perilaku pro-lingkungan dan (2) untuk menemukan hubungan antara kesadaran lingkungan dan perilaku pro-lingkungan di kalangan mahasiswa di Kota Malang. Penelitian ini menggunakan desain penelitian kuantitatif deskriptif dengan menggunakan metode survei. Data dikumpulkan dengan menggunakan instrumen kuesioner menggunakan 3 poin yang dimodifikasi dari skala respons Liker. Hasil penelitian menunjukkan bahwa mayoritas siswa memiliki kesadaran lingkungan yang lebih tinggi dan menunjukkan perilaku ramah lingkungan yang tinggi.


Makna Pernikahan Usia Dini Bagi Orang Tua Di Nagari Tapan, Kecamatan Basa Ampek Balai Tapan, Septra Yodi, Budijanto Budijanto, Singgih Susilo Jul 2024

Makna Pernikahan Usia Dini Bagi Orang Tua Di Nagari Tapan, Kecamatan Basa Ampek Balai Tapan, Septra Yodi, Budijanto Budijanto, Singgih Susilo

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Indonesia memiliki Undang-Undang yang mengatur tentang pernikahan yaitu Undang-Undang pernikahan nomor 1 tahun 1974 menjelaskan bahwa pernikahan dapat dilakukan apabila usia laki-laki berada diats 19 tahun dan usia perempuan berada diatas 16 tahun. Namun pernikahan usia dini di Nagari Tapan, Kecamatan Basa Ampek Balai Tapan selalu terjadi setiap tahun. Faktor penyebab terjadinya pernikahan usia dini yaitu factor pergaulan bebas, perekonomian, dan media massa. Penelitian ini dilakukan untuk mengungkapkan makna pernikahan usia dini bagi orang tua. Penelitian ini menggunakan jenis penelitian kualitatif dengan pendekatan keruangan Geografi. Penelitian kualitatif ini menggunakan pendekatan fenomenologi proposisi Alfred Schutz untuk mengetahui motive sebab (because motives) …


Bunching In Real-Estate Markets: Regulated Building Heights In New York City, Jan K. Brueckner, David Leather, Michael Zerecero Jul 2024

Bunching In Real-Estate Markets: Regulated Building Heights In New York City, Jan K. Brueckner, David Leather, Michael Zerecero

Business Faculty Articles and Research

This paper presents a real-estate application of the bunching methodology widely used in other areas of applied microeconomics. The focus is on regulated building heights in New York City, where developers can exceed a parcel’s regulated height by incurring additional costs. Using the bunching methodology, we estimate the magnitude of these extra costs, with the results showing a modest increase in the marginal cost of floor space beyond the regulated building height. We use these estimates to predict the additional floor space that would be created by complete removal of building-height regulation in NYC. While this last exercise is circumscribed …


Section Iii.A The Employment Situation, Bureau Of Labor Statistics Jul 2024

Section Iii.A The Employment Situation, Bureau Of Labor Statistics

Documentary Appendix to Table 1-B of Professor Thompson’s Book <em>The Trump v. Harris Voter’s Guide to Their Economic Debate</em> (2024)

No abstract provided.


Coexistence Of Large Cell Transformed Mycosis Fungoides And Diffuse Large B-Cell Lymphoma In One Patient, Thomas Z. Rohan, Jayson Suriano, Volkan Tekmen, Safiyyah Bhatti, Sahithi Talasila, Daniel Joffe, Caleb Holtmeyer, Jason B. Lee, Onder Alpdogan, Neda Nikbakht Jul 2024

Coexistence Of Large Cell Transformed Mycosis Fungoides And Diffuse Large B-Cell Lymphoma In One Patient, Thomas Z. Rohan, Jayson Suriano, Volkan Tekmen, Safiyyah Bhatti, Sahithi Talasila, Daniel Joffe, Caleb Holtmeyer, Jason B. Lee, Onder Alpdogan, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

Diffuse large B-cell lymphoma (DLBCL) is the most common and aggressive subtype of non-Hodgkin lymphoma. The overall risk of developing DLBCL is increased in patients with other lymphomas, such as mycosis fungoides (MF). In this report, we present an 81-year-old female with early-stage MF who simultaneously progressed to tumor stage, large-cell transformed (LCT) MF and developed a primary DLBCL in a lymph node (LN). She presented with a tumor on her leg and new lymphadenopathy in her right axilla. Skin biopsy of the tumor revealed infiltration of large atypical CD3+, CD4+, and CD30+ cells, and a smaller portion of CD8+ …


Metaboanalyst 6.0: Towards A Unified Platform For Metabolomics Data Processing, Analysis And Interpretation., Zhiqiang Pang, Yao Lu, Guangyan Zhou, Fiona Hui, Lei Xu, Charles Viau, Aliya F Spigelman, Patrick E Macdonald, David S Wishart, Shuzhao Li, Jianguo Xia Jul 2024

Metaboanalyst 6.0: Towards A Unified Platform For Metabolomics Data Processing, Analysis And Interpretation., Zhiqiang Pang, Yao Lu, Guangyan Zhou, Fiona Hui, Lei Xu, Charles Viau, Aliya F Spigelman, Patrick E Macdonald, David S Wishart, Shuzhao Li, Jianguo Xia

Faculty Research 2024

We introduce MetaboAnalyst version 6.0 as a unified platform for processing, analyzing, and interpreting data from targeted as well as untargeted metabolomics studies using liquid chromatography - mass spectrometry (LC-MS). The two main objectives in developing version 6.0 are to support tandem MS (MS2) data processing and annotation, as well as to support the analysis of data from exposomics studies and related experiments. Key features of MetaboAnalyst 6.0 include: (i) a significantly enhanced Spectra Processing module with support for MS2 data and the asari algorithm; (ii) a MS2 Peak Annotation module based on comprehensive MS2 reference databases with fragment-level annotation; …


Unpacking The Science Of Reading Research, Greta Rollo, Kellie Picker Jul 2024

Unpacking The Science Of Reading Research, Greta Rollo, Kellie Picker

Literacy and numeracy

The science of reading (SoR) is a term used for a body of evidence encompassing multi-disciplinary research from education, cognitive psychology, linguistics, and neuroscience. This evidence points to six key constructs that contribute to proficient reading: oral language, phonological awareness including phonemic awareness, phonics, fluency, vocabulary and reading comprehension. Research around these constructs provides researchers and teachers with an evidence base of the knowledge, skills and strategies involved in competent reading and describes how reading develops in both typical and atypical readers. This paper synthesises evidence reviews conducted by ACER researchers that unpack the science of reading. The aim of …


Inspire : Vol 7 Issue 7, Department Of Medicine Jul 2024

Inspire : Vol 7 Issue 7, Department Of Medicine

INSPIRE – Department of Medicine Archives

  • Message from the Chair
  • Medicine at National and International Forums
  • Question Development Retreat
  • Cardiology team achieves Platinum Performance Award!
  • Facebook live session
  • Dr Javaid A Khan takes Charge!
  • Featured Faculty: Dr. M Uzair Rauf
  • What Academics Are Reading This Month?
  • Upcoming event


Predicting Homelessness: Housing Risk Insights From Latent Class Analysis, Katherine E. Marcal, Nicholas Barr Jul 2024

Predicting Homelessness: Housing Risk Insights From Latent Class Analysis, Katherine E. Marcal, Nicholas Barr

Social Work Faculty Research

Millions of families with children in the U.S. struggle to afford adequate housing. Housing cost burden places families at risk for homelessness, and prevention efforts are hindered by limited understanding of insecure housing experiences at the margins. The present study investigated variation in housing insecurity experiences in a sample of mothers, as well as which risk profiles were most strongly associated with subsequent homelessness. Latent class analysis identified four distinct subgroups of housing insecurity: “Stable,” “Unstable,” “Rent-Focused,” and “Strategic Bill-Paying.” Classes differed on whether they made rent or utility payments on time, experienced utility shutoffs, or were evicted. Mothers who …


Olaparib For Childhood Tumors Harboring Defects In Dna Damage Repair Genes: Arm H Of The Nci-Cog Pediatric Match Trial, Julia L Glade Bender, Kerice Pinkney, Paul M Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent D Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Nilsa C Ramirez, Elizabeth Fox, Brenda J Weigel, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, Donald W Parsons Jul 2024

Olaparib For Childhood Tumors Harboring Defects In Dna Damage Repair Genes: Arm H Of The Nci-Cog Pediatric Match Trial, Julia L Glade Bender, Kerice Pinkney, Paul M Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent D Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Nilsa C Ramirez, Elizabeth Fox, Brenda J Weigel, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, Donald W Parsons

Center for Medical Ethics and Health Policy Staff Publications

Background: The National Cancer Institute-Children's Oncology Group Pediatric Molecular Analysis for Therapy Choice (MATCH) precision oncology platform trial enrolled children aged 1-21 years with treatment-refractory solid tumors and predefined actionable genetic alterations. Patients with tumors harboring alterations in DNA damage repair (DDR) genes were assigned to receive olaparib.

Methods: Tumor and blood samples were submitted for centralized molecular testing. Tumor and germline sequencing were conducted in parallel. Olaparib was given twice daily for 28-day cycles starting at a dose 30% lower than the adult recommended phase 2 dose (RP2D). The primary endpoint was the objective response.

Results: Eighteen patients matched …


Cell-Specific Single Viral Vector Crispr/Cas9 Editing And Genetically Encoded Tool Delivery In The Central And Peripheral Nervous Systems, Jamie C Moffa, India N Bland, Jessica R Tooley, Vani Kalyanaraman, Monique Heitmeier, Meaghan C Creed, Bryan A Copits Jul 2024

Cell-Specific Single Viral Vector Crispr/Cas9 Editing And Genetically Encoded Tool Delivery In The Central And Peripheral Nervous Systems, Jamie C Moffa, India N Bland, Jessica R Tooley, Vani Kalyanaraman, Monique Heitmeier, Meaghan C Creed, Bryan A Copits

2020-Current year OA Pubs

CRISPR/Cas9 gene editing represents an exciting avenue to study genes of unknown function and can be combined with genetically encoded tools such as fluorescent proteins, channelrhodopsins, DREADDs, and various biosensors to more deeply probe the function of these genes in different cell types. However, current strategies to also manipulate or visualize edited cells are challenging due to the large size of Cas9 proteins and the limited packaging capacity of adeno-associated viruses (AAVs). To overcome these constraints, we developed an alternative gene editing strategy using a single AAV vector and mouse lines that express Cre-dependent Cas9 to achieve efficient cell-type specific …


Examining The Digital Literacy Competencies And Practices Of Generation Z Employees In Higher Education, Ashlea L. Wilson Jul 2024

Examining The Digital Literacy Competencies And Practices Of Generation Z Employees In Higher Education, Ashlea L. Wilson

Human Resource Development Theses and Dissertations

The purpose of this study was to examine the digital literacy of Gen Z employees in higher education and provide implications for HRD research and practice and contribute to the HRD literature on Gen Z employees in the 21st century workforce. Three research questions guided my study: How do Gen Z employees in higher education experience digital literacy? What digital literacy skills gaps exist in Gen Z employees in higher education? And what can higher education institutions do to close the digital literacy gap for Gen Z employees entering the workforce? To examine the lived experiences of Gen Z employees’ …


A Biobehavioral Observational Study To Understand The Multilevel Determinants Of Cardiovascular Health In Black Women: The Bloom Study Protocol, Yue Liao, R. Matthew Brothers, Kyrah K. Brown, Rebecca E. Lee Jul 2024

A Biobehavioral Observational Study To Understand The Multilevel Determinants Of Cardiovascular Health In Black Women: The Bloom Study Protocol, Yue Liao, R. Matthew Brothers, Kyrah K. Brown, Rebecca E. Lee

Open Initiatives Grant Funded Publications-Archive

Background The racial/ethnic and gender disparities in cardiovascular disease (CVD) morbidity and mortality in the United States are evident. Across nearly every metric, non-Hispanic Black women have poorer overall cardiovascular health. Emerging evidence shows a disproportionately high burden of increased CVD risk factors in Black women of childbearing age, which has a far-reaching impact on both maternal and child outcomes, resulting in premature onset of CVD and further widens the racial disparities in CVD. There is growing recognition that the fundamental driver of persistent racial/ethnic disparities in CVD, as well as disparities in behavioral risk factors such as physical activity …


Malposition Of Percutaneous Endoscopic Gastrostomy (Peg) Tube Through The Transverse Colon: A Novel Approach To Conservative Management, Joel Calafell Jul 2024

Malposition Of Percutaneous Endoscopic Gastrostomy (Peg) Tube Through The Transverse Colon: A Novel Approach To Conservative Management, Joel Calafell

All Publications

Percutaneous endoscopic gastrostomy (PEG) is a common technique for enteral nutrition support. Complications range from skin injuries and leakage to more severe intraabdominal pathologies. This case report describes a patient with invasive right lateral pharyngeal wall squamous cell carcinoma who developed a gastrocolocutaneous fistula following PEG tube malpositioning in the transverse colon performed at an outside institution. Based on the patient's comorbidities and the associated high-risk nature of the surgery, a transverse colectomy and partial gastrectomy to resect the malpositioned tube followed by a new PEG tube was deemed invasive and would likely have a poor clinical outcome. Instead, the …


Successful Rhinophyma Treatment Utilizing The Versajet Ii Hydrosurgery System: A Case Report And Systematic Review Of The Literature, Rafael Gottenger Jul 2024

Successful Rhinophyma Treatment Utilizing The Versajet Ii Hydrosurgery System: A Case Report And Systematic Review Of The Literature, Rafael Gottenger

All Publications

Rhinophyma, characterized by hypertrophy of sebaceous glands, often necessitates surgical intervention. This is the second case report of the off-label use of the Versajet II Hydrosurgery System (VJHS) (Smith & Nephew, London, UK) in the United States for the treatment of rhinophyma and the first systematic review of the literature, emphasizing its efficacy and safety for this indication. A surgical debulking and resurfacing was performed on a patient with rhinophyma. The patient underwent general anesthesia along with bilateral infraorbital blocks and local infiltration of lidocaine 1% with epinephrine. The VJHS was utilized for progressive debulking followed by debridement using sharp …


Ud In The News June 29-July 5, University Of Dayton Jul 2024

Ud In The News June 29-July 5, University Of Dayton

News Releases

The New York Times interviewed Associate Professor Haozhou Pu on China’s coverage of Olympic athlete doping cases. Professor Charlie Russo explained the significance of a Catholic charter school case to a national audience in The Conversation. Associate Professor Christopher Devine discussed the veepstakes across international, national and regional news outlets, including Connecticut Public Radio, The National Desk, and the New York Post.


Transcriptional Precision In Photoreceptor Development And Diseases - Lessons From The Retinal Transcription Factor Crx, Yiqiao Zheng Jul 2024

Transcriptional Precision In Photoreceptor Development And Diseases - Lessons From The Retinal Transcription Factor Crx, Yiqiao Zheng

Arts & Sciences Graduate Student Theses and Dissertations

Precise gene expression programs are foundational to organism development and homeostasis. Transcription factors play a central role in establishing and maintaining these programs. Large-scale transcriptomic studies have generated parts lists of transcription factors. However, these descriptive works rarely formulate a cohesive model of how these transcription factors work together to support a functional organism. Mutations that affect transcription factor functions can lead to a broad range of human diseases. Therefore, it is crucial to understand the principles that transcription factors achieve spatial, temporal, and quantitative precision in their regulated gene expression programs. I have investigated transcriptional regulation in rod and …


Fort Hays State University Tiger Weekly, July 05, 2024, University Relations Jul 2024

Fort Hays State University Tiger Weekly, July 05, 2024, University Relations

Tiger Weekly Newsletters

No abstract provided.


The Effect Of Chronic Exercise On The Self-Perceived Mental Well-Being Of College Students, Joshua Hardy Jul 2024

The Effect Of Chronic Exercise On The Self-Perceived Mental Well-Being Of College Students, Joshua Hardy

Research Papers

No abstract provided.


Exploring Parent Engagement In School-Based Behavioral Health Programs, Tina Marie Wehner Hickman Jul 2024

Exploring Parent Engagement In School-Based Behavioral Health Programs, Tina Marie Wehner Hickman

Walden Dissertations and Doctoral Studies

It is important to address the concept of parental involvement in school-based mental health counseling in order to address the presence of mental health issues in students. In school-based mental health services, enlisting parent engagement in adolescent interventions can be difficult and can, therefore, inhibit positive adolescent mental health outcomes. This case study examined an educational organization in the southwestern United States to identify barriers inhibiting parent involvement in adolescent school-based mental health and to explore strategies to encourage parent engagement. The Baldrige performance excellence framework was utilized as a guide to inform an understanding of the organization’s mission, strategic …


Dissociation Of Reading And Naming In Ventral Occipitotemporal Cortex, Oscar Woolnough, Nitin Tandon Jul 2024

Dissociation Of Reading And Naming In Ventral Occipitotemporal Cortex, Oscar Woolnough, Nitin Tandon

Faculty, Staff and Student Publications

Lesions in the language-dominant ventral occipitotemporal cortex (vOTC) can result in selective impairment of either reading or naming, resulting in alexia or anomia. Yet, functional imaging studies that show differential activation for naming and reading do not reveal activity exclusively tuned to one of these inputs. To resolve this dissonance in the functional architecture of the vOTC, we used focused stimulation to the vOTC in 49 adult patients during reading and naming, and generated a population-level, probabilistic map to evaluate if reading and naming are clearly dissociable within individuals. Language mapping (50 Hz, 2829 stimulations) was performed during passage reading …


Genetic Diversity Of 1,845 Rhesus Macaques Improves Genetic Variation Interpretation And Identifies Disease Models, Jun Wang, Meng Wang, Ala Moshiri, R Alan Harris, Muthuswamy Raveendran, Tracy Nguyen, Soohyun Kim, Laura Young, Keqing Wang, Roger Wiseman, David H O'Connor, Zach Johnson, Melween Martinez, Michael J Montague, Ken Sayers, Martha Lyke, Eric Vallender, Tim Stout, Yumei Li, Sara M Thomasy, Jeffrey Rogers, Rui Chen Jul 2024

Genetic Diversity Of 1,845 Rhesus Macaques Improves Genetic Variation Interpretation And Identifies Disease Models, Jun Wang, Meng Wang, Ala Moshiri, R Alan Harris, Muthuswamy Raveendran, Tracy Nguyen, Soohyun Kim, Laura Young, Keqing Wang, Roger Wiseman, David H O'Connor, Zach Johnson, Melween Martinez, Michael J Montague, Ken Sayers, Martha Lyke, Eric Vallender, Tim Stout, Yumei Li, Sara M Thomasy, Jeffrey Rogers, Rui Chen

Faculty, Staff and Students Publications

Understanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequencing on 1845 individuals for 374 genes linked to inherited human retinal and neurodevelopmental diseases. We identify over 47,000 single nucleotide variants, a substantial proportion of which are shared with human populations. By combining rhesus and human allele frequencies with established variant prediction methods, we develop a machine learning-based score that outperforms established methods in predicting missense variant pathogenicity. Remarkably, we find a marked number of loss-of-function variants and putative deleterious variants, which …