Digital Commons Network^™

Impact Of Dietician Counseling On Outcomes In Newly Diagnosed Celiac Disease, Andreas Mozny B.A., Alyusuf Elnaggar B.A., James Mo M.D., Suraj Suresh M.D.

Medical Student Research Symposium

Title: Impact of Dietician Counseling on Outcomes in Newly Diagnosed Celiac Disease

Background: Dietician counseling is routinely recommended for newly diagnosed celiac disease (CD), yet its measurable impact is not well defined. This study examined whether early dietician involvement improves clinical symptoms or serologic outcomes.

Methods: We retrospectively reviewed adults with biopsy-confirmed CD at a single center from 2020–2024. Demographics, symptoms, and laboratory data were collected by chart review with ≥6 months of follow-up. Patients who met with a dietician formed the dietician group; all others were assigned to the non-dietician group. Fisher's Exact tests evaluated abdominal …

Promising Efficacy Of Avapritinib In Pdgfra Ecdna–Amplified Glioblastoma, Sydni Rosenfeld, Artem Berezovsky, Indrani Datta, Andrea Transou, Susan Irtenkauf, Laura Hasselbach, Ana C. Decarvalho

Medical Student Research Symposium

Background: Avapritinib, a selective inhibitor of mutated class III receptor tyrosine kinases (RTKs), shows promise in PDGFRA-altered pediatric glioma. We studied its efficacy in a glioblastoma (GBM) model (HF3253) containing two PDGFRA alterations: constitutive activation via an indel mutation and extrachromosomal DNA (ecDNA) amplification. We hypothesized that Avapritinib would preferentially improve survival in PDGFRA-amplified tumors.

Methods: Orthotopic xenografts derived from HF3253 PDGFRA ecDNA(+) (n=19) and ecDNA(-) (n=10) cells were treated with 40 mg/kg Avapritinib (5 days/week). To validate the role of PDGFRA expression, wild-type PDGFRA was overexpressed in ecDNA(-) cells, generating high PDGFRA levels with minimal ligand-independent activation in vivo. …

Speed And Cosmetic Outcomes Of Skin Closure Methods In Head And Neck Surgery: A Network Meta-Analysis Of Randomized Trials, Marcel Addis Jackson, Jacob Nielsen, John Cramer

Medical Student Research Symposium

Background The optimal skin-closure technique in head and neck surgery is uncertain, with sutures, staples, and tissue adhesive (glue) all in common use.

Objective To compare time to skin closure, postoperative scar appearance, overall surgical time, and cost across sutures, staples, and glue in head and neck surgery.

Methods We systematically screened 549 records in Covidence and included prospective randomized controlled trials comparing sutures vs staples, staples vs glue, or glue vs sutures. Eight trials met eligibility; six were pooled and two summarized narratively. A random-effects network meta-analysis (MetaInsight) evaluated two primary outcomes: time to skin closure and scar score …

Enhanced Control Of Central Sleep Apnea With Adjunctive Therapy: Cpap Plus Oxygen And/Or Acetazolamide., Ali J. Mustapha, Maria Fatima, S. Shanker, A. Aldiwaikat, M. Habra, K. Jackson, S. Habra, M. Bawa, A. Moustapha, N. Pandya, S. Gosh, A. Sankari, M.S. Badr

Medical Student Research Symposium

Background: Effective Treatment of central sleep apnea (CSA) remains elusive. CPAP may be an efficacious treatment for CSA, but it rarely eliminates CSA. The purpose of this investigation was to determine the efficacy of adding acetazolamide, low-flow oxygen, or both to CPAP therapy for CSA treatment.

Methods: A controlled, double-blinded, crossover study evaluated the efficacy of acetazolamide, supplemental oxygen, and their combination in reducing sleep-disordered breathing compared with standard PAP therapy. All 82 participants completed full polysomnography under five conditions: (1) Baseline, (2) Baseline PAP, (3) Acetazolamide at 250 mg at bedtime, (4) low-flow Oxygen ( 2-4 L/min), and (5) …

Assessing The Reproductive Potential Of Late Mature Cryopreserved Oocytes, Keri Bergin, Ashna Mehra

Medical Student Research Symposium

Title: Assessing the reproductive potential of late mature cryopreserved oocytes

Authors: Keri Bergin, Ashna Mehra, Rick Slifkin, Morgan Baird, Dmitry Gounko, Carlos Hernandez-Nieto, Joseph Lee, Chelsea Canon, Alan B Copperman, Lucky Sekhon

Background:

Oocytes retrieved at the germinal vesicle (GV) or metaphase I (MI) stage may mature in vitro to MIIs for cryopreservation. Limited data exist on the reproductive potential of late mature MIIs after thaw. This study assesses the thaw, fertilization, and embryo development outcomes of late mature versus immediately mature cryopreserved oocytes.

Methods:

This retrospective cohort study analyzed autologous oocyte cryopreservation cycles with thaws from January 2016 – …

Oct Evidence Supports Oxidative Stress And Retinoid Deficiency But Not Mitochondrial Inefficiency During Healthy Human Aging, Laura Zvinys, Ehimenmen Ataman, Sukhanjit Kaur, Saleh Ahmed, Madelyn Moretti, Megan Johnson, James Soetedjo, Harman Bindra, Emmaline O'Neil, Rida Waseem, Yannick Liermann, Sarah Thiele, Bruce Berkowitz Phd

Medical Student Research Symposium

Background: To test for evidence of macula oxidative stress, impaired retinoid handling, and/or photoreceptor energy inefficiencies during healthy human aging as measured by next-generation OCT biomarkers.

Methods: OCT was used to examine light-adapted 20-30 and 70-90-year-old, male and female subjects without overt ophthalmologic disease. Two biomarkers were measured: 1) external limiting membrane (ELM) to retinal pigment epithelium (RPE) contraction, which can arise from oxidative stress-induced acidosis and is concordant with impaired spatial distribution of 11-cis retinal chaperone retinal binding protein 3, and 2) the sub-ELM hyperreflective band profile shape, or Mitochondria Configuration within Photoreceptor inner segments measured with …

Twice As Long, Half The Risk: Piccs Outperform Cvcs In Pediatric Burn Patients, Christian Hudson-Bradford Md, Megan Zacarias Bs, Samantha Carranza Bs, Elika Ridelman Phd, Christina Shanti Md

Medical Student Research Symposium

Title: Twice as Long, Half the Risk: PICCs Outperform CVCs in Burn Patient

Christian Hudson-Bradford MD, Megan Zacarias BS, Elika Ridelman PhD, Samantha Carranza BS, Christina Shanti MD

Background: Venous access is critical in burn care for fluid resuscitation, medication delivery, and nutritional support. While central venous catheters (CVCs) are traditionally used, peripherally inserted central catheters (PICCs) offer an alternative option with a potentially favorable safety profile, longer dwell time, and reduced need for re-insertion. This study compares patient characteristics, complication rates, and catheter duration between PICC and CVC lines in pediatric burn patients, advocating for early PICC …

Comparison Of Non-Invasive Methods For Measuring Intracranial Hypertension, Danielle Santoyo, B.S., Eric Mylfurry, B.S., Marilyn Li, B.S., Matthew Mellor, B.S., Mercylia Untono, B.S., Urva Mehveen, B.S., Hari Ramakrishnan, B.S., James Paxton, M.D., M.B.A.

Medical Student Research Symposium

Introduction and Purpose of Review:

Intracranial hypertension (IHTN) is a serious complication associated with neurological injuries. Once IHTN is detected, it is crucial to make swift decisions regarding medical treatments. This review focuses on the effectiveness and utility of noninvasive methods used to detect IHTN in the emergency department (ED).

Methods:

We conducted a comprehensive search for PubMed articles to find data on non-invasive intracranial pressure (ICP) evaluation methods including; optic nerve sheath diameter ultrasound (ONSS), automated infrared pupillometry (AIP), Tympanic Membrane Displacement (TMD), Transcranial Doppler Ultrasound (TDU), CT, and MRI. We compared; cost, accuracy, estimated time per method, specificity …

Federated Cognitive Twins, Johny Manuel-Devadoss, Joanna Johnson, Jayden Johnson

Defensive Publications Series

The current generation of personalization systems is fundamentally constrained by a centralized representational paradigm in which users are reduced to static behavioral embeddings owned and monetized by platform operators. Existing recommender architectures infer preference vectors from fragmented interaction telemetry and optimize engagement through increasingly opaque reinforcement pipelines. Such systems exhibit severe deficiencies in epistemic continuity, user sovereignty, contextual cognition, longitudinal identity fidelity, and privacy-preserving personalization. This paper introduces Federated Cognitive Twins (FCT), a next-generation computational architecture for continuously evolving, cryptographically sovereign, locally anchored cognitive simulations representing human behavioral dynamics, ethical priors, attentional signatures, learning topology, persuasion resistance characteristics, trust propagation …

Characterization And Potential Suitability Of Some Egyptian Clays For Ceramic Building Applications, Marwa Askar, Medhat Sobhy El-Mahllawy, Mohamed Hamed Abdel-Aal, Ali Mohamed Ali Abd-Allah, Safia Gaber Al Menoufy

HBRC Journal

This study investigates the suitability of five Egyptian clay deposits—Wadi El-Natrun, Qasr El-Sagha, Kafr Homied, Fayed, and Suez Road—for ceramic building applications. Representative samples were characterized chemically and mineralogically, with grain size distribution and Atterberg limits determined to assess their industrial potential. Mineralogical analysis identified montmorillonite, illite, and kaolinite as the dominant clay minerals. Grain size and plasticity data, plotted on industrial diagrams, revealed that all samples are highly plastic clays with elevated clay fractions and minimal sand content. Such properties, while beneficial for molding, require modification to reduce excessive plasticity. The addition of non-plastic materials is recommended to enhance …

Effect Of Spry Of Potassium Ratio And Cycocel On Physiological Traits Of Maize (Zea Mays L), Asmaa Mohammed Hussein, Eabdallah Yasin Ali

AUIQ Complementary Biological System

The aim of this work was to investigating the effect of foliar application of potassium (K) and the growth regulator Cycocel (CCC) on the physiological traits of maize (Zea mays L). The experiment was designed using a split-plot arrangement within a randomized complete block design (RCBD) with three replicates. The treatments included foliar application of potassium at concentrations of 500, 1000, and 1500 mg.L^–1, as well as three concentrations of the growth regulator Cycocel (0, 150, and 200 mg.L^–1). The results indicated a significant increase in Protein (P), phosphorus, and carbohydrate contents at the concentration of …

Metabolic Reversal Without Ldl Normalization: A 4-Month Lifestyle Intervention Case Report Of Severe Youth Obesity With Persistent Ldl Elevation, Harpreet Kour, Madhav Prabhu, Vikrant Ghatnatti

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Severe obesity in young adults is increasingly common, even among medical students. Lifestyle modification remains the cornerstone of management, but the differential response of various lipid parameters is often misunderstood. Case Summary: A 19-year-old first-year MBBS student presented with BMI 41 kg/m² (weight 105 kg, height 160 cm), waist circumference 100 cm, WHR 1.2, and blood pressure 130/86 mmHg. Laboratory evaluation revealed: Total Cholesterol 256 mg/dL, HDL 34 mg/dL, LDL 180 mg/dL, Triglycerides 386 mg/dL, TG/HDL ratio 11.35, high fasting insulin, elevated HOMA-IR, normal hemoglobin (14 g/dL), ferritin (76 ng/mL), and Vitamin B12 (386 pg/mL), with Vitamin D …

Impact Of 4-Week Brain Gym Exercise Program On Fine Motor Skills And Hand Grip Strength In Autism Spectrum Disorder: A Case Study, Harita Sonawane, Tejas Borkar

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Autism Spectrum Disorder is a neurodevelopment disorder characterized by affection in gross and fine motor development, motor coordination abnormalities, and deficiencies in motor planning, social interactions and communication. Brain Gym exercises have drawn interest due to its potential advantages in improving bilateral integration, dexterity, and fine motor abilities, especially in children with autism. Objectives: To evaluate the impact of 4-week Brain gym exercise program on fine motor skills and Hand-grip strength in autism spectrum disorder. Methodology: This case report focuses on a 9-year-old male child with a range of developmental abnormalities such as difficulty in fine motor tasks, difficulty …

The Minimalist Footwear Paradox: Unloading The Foot, Overloading The Bone, Shrihari L Kulkarni, Harpreet Kour

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Minimalist footwear (MF) and barefoot walking and running are increasingly adopted in India, often using low-cost flat shoes or no footwear at all. However, abrupt transition on hard urban surfaces (concrete, marble, tile) may predispose to metatarsal stress fractures, plantar fasciopathy, and Achilles' tendinopathy. Objective: To synthesize current biomechanical and physiological evidence on MF transition and present clinical case data from a single centre in North Karnataka. Methods: We reviewed published studies examining bony strain, intrinsic foot muscle adaptation, and injury rates following MF use. Additionally, we present representative clinical cases from combined Orthopaedics and Physiology outpatient services (January …

Early Experiential Learning To Foster Cultural Responsiveness In Medical Students, Shilpa Hd, Archana Shetty

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Long-Term Effects Of Whole-Body Vibration Combined With Conventional Physiotherapy In Dravet Syndrome: A Case Report, Vaishnavi Dhumal, Dr. Tejas Borkar (Pt)

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Significant motor deficits are linked to Dravet Syndrome, a rare developing epileptic encephalopathy. Whole-body vibration (WBV) is one of the emerging rehabilitation techniques that has drawn interest due to its ability to improve postural control and neuromuscular function in various neurological conditions. Objectives: To assess effectiveness of conventional physiotherapy along with WBV, on motor development in a patient with Dravet syndrome. To assess the long term effects of conventional physiotherapy adjunct to WBV. Case presentation: Following his first febrile seizure at three months, a 15-month-old boy with global developmental delay was diagnosed with Dravet syndrome. A pathogenic SCN1A mutation …

Clinical Profile Of Hyponatremia And Its Impact On Activities Of Daily Living Among Older People (A Prospective Observational Study), Kushal Bhangale, Aniruddha Umarji, Anand Ambali, Muddasir Indikar

Indian Journal of Health Sciences and Biomedical Research KLEU

Introduction: Hyponatremia is a common, serious problem among older people. The aetiology is multifactorial and has a significant association with different comorbidities, which makes it pertinent to identify the underlying causes, and it has a negative impact on activities of daily living (ADL). In this study, we tried to correlate the impact of hyponatremia on activities of daily living. Methodology: A prospective observational study was conducted in the intensive care unit of Shri B M Patil Medical College and Hospital, Vijayapura, on one hundred consecutive elderly patients admitted with true hyponatremia for twelve months. Detailed medical history, clinical examination, laboratory …

Influence Of Chitosan In Bone Regenerative Biomaterials – A Systematic Review Of In-Vivo Studies, Reetika Gaddale, Ramesh Chowdhary

Indian Journal of Health Sciences and Biomedical Research KLEU

Chitosan-based biomaterials are biocompatible, biodegradable and can be formed into composites, scaffolds and hydrogels, making it an ideal candidate in the application of bone tissue engineering. Addition of growth factor, bioactive molecules and nanoparticles to chitosan promotes osteogenesis and angiogenesis, thereby enhancing bone repair. But further research is needed due to challenges like its limited mechanical strength and stability under physiological conditions. So, the focus question of this review was ``Is the use of chitosan-based biomaterials effective in promoting bone regeneration.'' Electronic literature review was conducted on Medline/PubMed, Embase, Web of Science databases, without any limitations on the year of …

From Bench To Publication: The Hidden Crisis Of Reproducibility In Biomedical Research, Punnya. V. Angadi

Indian Journal of Health Sciences and Biomedical Research KLEU

Reproducibility serves as a fundamental aspect of biomedical research, guaranteeing that findings are reliable, precise, and relevant to clinical applications. The growing difficulty in replicating research outcomes has led to what is known as the ``reproducibility crisis.'' This issue has a profound impact on the biomedical field, affecting pharmaceutical research, guiding medical treatment decisions, and influencing public health results. This editorial aims to examine the extent, root causes, and consequences of irreproducibility in biomedical research, with a focus on the contributions of methodological errors, publication biases, and the pressures exerted by academic systems. Additionally, it will propose possible solutions to …

Scope Of Utilizing Waste Marble Dust In Concrete: Statistical And Surface Response Approach, Khatib Zada Farhan

Journal of King Abdulaziz University: Engineering Sciences

The sludge produced from marble processing has become a significant environmental hazard in major marble mining and processing countries. Utilizing marble dust (MD) as a partial replacement for cement offers benefits: it reduces the need for landfill disposal, which can lead to air and water pollution, and it decreases the consumption of cement, which contributes to the global carbon footprint. This study examines the key properties of concrete incorporated with MD and develops a composite mix with the optimal MD content using response surface methodology. The influence of MD/Cement ratio, Water/Cementitious material ratio, and parameters indicating important constitutive elements in …

Meteorological Influence On Site Selection For A Hypothetical Nuclear Power Plant Near Yanbu, Saudi Arabia, Abdulwahab Albesher, Daud Bin Mohamad, Mohammed M. Damoom, Othman A. Fallatah

Journal of King Abdulaziz University: Engineering Sciences

Kingdom of Saudi Arabia (KSA) is known as a heavy reliant oil country particularly for economic and energy sectors. KSA seeks to diversify their economy and energy sources and gradually phase out oil dependance to achieve net zero emission by 2060. Nuclear energy is a reliable energy source that can replace oil. KSA had declared previously on multiple occasions that they wish to enrich their nuclear fuel from their uranium reserve. There are numbered studies regarding suitability of Nuclear Power Plant (NPP) sites in KSA mainly focused on geological and geographic aspects. One of these sites was Yanbu city. The …

Radiation Exposure And Safety Practices In Dental Radiology: A Literature Review, Abdullah Awn Alsubaie, Majdi Rashed Alnowaimi, Nada Othman Bamashmous, Afnan Darwesh, Abdu Mohammed Saeed, Essam Mohammed Banoqitah

Journal of King Abdulaziz University: Engineering Sciences

Background: Although exposure to even low doses of ionizing radiation can cause cell damage and increase the risk of cancer, dental radiography remains an essential tool for making the correct diagnosis and planning treatment. Despite the advancements in dental radiography, significant global variations in the knowledge, attitudes, and practices (KAP) of dental professionals persist, including those practicing in the Middle East and Saudi Arabia. Its continued necessity highlights the importance of continuously and thoroughly evaluating the compliance to safety standards according to international guidelines. Aim: This review aims to ascertain prevailing occupational radiation exposure levels, evaluate the knowledge and awareness, …

U.S. Small Food And Beverage Businesses Sustainability Strategies, Berenice Mulubah

Walden Dissertations and Doctoral Studies

No abstract provided.

Evaluating The Association Between Chronic Health Conditions And Caregiver Burden For Male Dementia Caregivers, Dareion D. Hill-Smith

Walden Dissertations and Doctoral Studies

No abstract provided.

Embedding Clinical Application Assignments In Dnp Education: A Model For Practice Hour Acquisition, Cynthia Plonien

Nursing Faculty Publications & Presentations

Doctor of Nursing Practice (DNP) programs must ensure graduates complete a minimum of 1,000 post-baccalaureate clinical/practice hours aligned with the American Association of Colleges of Nursing (AACN) Essentials. As programs transition to accelerated and online formats, achieving these hours has become increasingly challenging, particularly for students entering without prior supervised clinical experience. Traditional models relying on terminal practicum courses often create feasibility limitations and variability in the quality of practice experiences. This article describes an innovative curricular model that embeds Clinical Application Assignments (CAAs) across didactic coursework to support longitudinal acquisition of clinical hours. This approach provides a feasible and …

Evidence-Based Approaches To Managing Adolescent Aggression, April Dade

Walden Dissertations and Doctoral Studies

No abstract provided.

The Lived Experience Of African Immigrants Receiving Mental Health Services In The U.S., Ori Adure Onazi

Walden Dissertations and Doctoral Studies

No abstract provided.

Exploring The Impact Of Mental Health On Childhood Obesity In Southern African American Youth Ages 12-18, Shari Scott Robinson

Walden Dissertations and Doctoral Studies

No abstract provided.

Improving Enrollment, Transfer, And Discharge Workflows In Integrated Behavioral Health And Primary Care Settings, Matthew Clark

Walden Dissertations and Doctoral Studies

No abstract provided.

Teaching Motivational Interviewing Techniques To Nursing Staff To Improve Glycemic Control In Patients With Diabetes, Augustine Ngouondjyou Fotsing

Walden Dissertations and Doctoral Studies

No abstract provided.