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Mathematical Modelling And Analysis For The Co-Infection Of Viral And Bacterial Diseases: A Systematic Review Protocol, Timothy Kiprono Yano, Ebenezer Afrifa-Yamoah, Julia Collins, Ute Mueller, Steven Richardson

Research outputs 2022 to 2026

Introduction Breaking the chain of transmission of an infectious disease pathogen is a major public health priority. The challenges of understanding, describing and predicting the transmission dynamics of infections have led to a wide range of mathematical, statistical and biological research problems. Advances in diagnostic laboratory procedures with the ability to test multiple pathogens simultaneously mean that co-infections are increasingly being detected, yet little is known about the impact of co-infections in shaping the course of an infection, infectivity, and pathogen replication rate. This is particularly true of the apparent synergistic effects of viral and bacterial co-infections, which present the …

Biostatistik In Ophthalmologie Und Optometrie: Eine Artikelserie Zur Unterstützung Evidenzbasierter Entscheidungsprozesse, Daniela Oehring, Pedro Miguel Serra

School of Health Professions

Zweck. Fortschritte in der Augen- und Sehversorgung basieren auf der Anwendung von Forschungsergebnissen und der präzisen Interpretation klinischer Daten. Dennoch treten in der Augen- und Sehforschung (EVR) häufig Forschungsverschwendungen auf, bedingt durch methodische Mängel und unangemessene statistische Analysen. Dies untergräbt die Validität von Studien und führt zu ineffizienter Nutzung erheblicher finanzieller Ressourcen. Dieser Artikel, der erste Teil der Serie „Entwicklung statistischer Kompetenzen in der Augenheilkunde: Eine Reihe zur Unterstützung evidenzbasierter Entscheidungsprozesse”, zielt darauf ab, diese Herausforderungen anzugehen, indem er die statistische Kompetenz von Fachkräften in der Augenheilkunde stärkt.Material und Methoden. Anhand einer umfassenden narrativen Literaturübersicht und der Erstellung simulierter klinischer …

Shalom In Social Media Marketing Shalom In Social Media Marketing, Jill R. Risner, Thomas Betts

University Faculty Publications and Creative Works

This paper will examine social media and the ways in which it currently does and does not contribute to shalom through an examination of both the platforms themselves as well as the content shared through them. As Christ’s ambassadors in the world and the primary funders of social media, marketers have power and an obligation to consider social media’s impact on shalom in the world and to use it in ways that contribute to shalom. This paper will provide several recommendations of how marketers can do this including posting content that intentionally contributes to shalom, engaging on platforms that support …

Professional Identities, Culture And Pillars, Ralph Hammond

South West Clinical School Journal

No abstract provided.

Evaluating The Impact Of A Walking Group On Staff Well-Being And Compassionate Care In Mental Health Inpatient Services, Amanda Glanville

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Evaluating The Impact Of Staff Attitudes And Behaviours On Hospital-Associated Deconditioning, Cheryl Kent

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Facilitating Friendship Maintenance For People With Aphasia, Tom Williams

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Haematinics Assessment Prior To Commencing Systemic Anti-Cancer Therapy To Prevent Anaemia, Reduce Transfusion Requirements, And Improve Treatment Outcomes, Lee Merry

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Implementing A Patient Reported Experience Measure To A Home-Based Intermediate Care Service In Cornwall, Bethan Allen

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Managing Metabolic Osteoarthritis In Primary Care: A Survey Of First Contact Physiotherapist’S Knowledge, Confidence And Role Perception, Kate Preston, Clare Cambray, Mike Henning

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWSHIP PROGRAMME

The Efficacy Of Transcutaneous Electrical Stimulation In Reducing Acute Phantom Limb Pain: Patients’ Perspectives, Jennifer Bernthal

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Fraud Mitigation By Embodying Maqashid Sharia Values And Islamic Work Ethics, Farah Nurani Qorny, Sugiyarti Fatma Laela, Ahmad Levi Fachrul Avivy

Jurnal Akuntansi dan Keuangan Indonesia

This research examines how the fraud square influences fraud, and investigates whether implementing tahdzib al-fard (educating individuals), part of Maqashid Sharia values, and Islamic Work Ethics (IWE), can reduce employee involvement in fraud. The study uses a quantitative approach with questionnaires for data collection, with 257 civil servants in Banten Province agencies, Indonesia, as study samples. The data were further tested using partial least squares structural equation modeling. The study reveals that pressure, opportunity and rationalization have a positive relationship with fraud, while integrity has no impact on fraud deterrence. Tahdzib al-fard significantly influences employee perceptions and attitudes towards dealing …

The Radical Oxidation Of Hydroxyacetone: An Insight Into The Reaction Mechanism And Potential Tetraoxide Intermediates, Edward Buck

Master's Theses

This thesis presents the reaction of hydroxyacetone, a common volatile organic compound (VOC), with chlorine radicals in the presence of oxygen. Chapter one explores VOCs and their specific reactions and how tetraoxide intermediates could be formed from them. Chapter two analyses the experimental and computational methods used and the key theoretical concepts behind these methods. Experimental data was collected using multiplexed photoionization mass spectrometry at the Advanced Light Source Chemical Transformations Beamline, Lawrence Berkeley National laboratory. This data is combined with theoretical data using the CBS-QB3 composite method to determine the key reaction intermediates and mechanisms.

The main chapter of …

Research Focusing On Protective Factors: From Individual To Community And Societal Strengths, Maria Caridad H. Tarroja

Asia-Pacific Social Science Review

No abstract provided.

Empowering Local Heroes: A Study On Mindfulness, Self-Core Evaluation, And Agreeableness In Indonesian Climate Village Program, Daniswara Krisna Prabatha, Seger Handoyo, Suryanto Suryanto

Asia-Pacific Social Science Review

This comprehensive study explores the intersection of mindfulness, self-core evaluation, and agreeableness with local hero leadership, a similar framework to servant leadership, within Indonesia’s Climate Village Program (ProKlim). Employing a quantitative research methodology, this paper examines how these psychological traits impact the effectiveness of local hero leadership, a pivotal element in community-driven environmental initiatives. The study's aim is to understand the impact of the local hero's nature and character on leading ProKlim effectively. The research investigates the role of a local hero as a servant leader, delving into how mindfulness contributes to awareness and responsiveness, how self-core evaluation relates to …

A Catholic Positive Youth Development Model Based On The Context Of The Catholic Church In Thailand, Sarawin Patsriruang

Asia-Pacific Social Science Review

In 2007, the Catholic Youth Council of Thailand was restructured into the Catholic Commission for Laity on Youth Desk to collaborate with all Catholic youth organizations in Thailand and expand the work of Catholic youth development. Despite the announcement of its 10 major youth development plans since 2015, there is still an opportunity to incorporate the widely adopted Positive Youth Development (PYD) approach into its projects and programs. Similarly, research on Catholic youth development reveals a gap in the concrete application of PYD. To address these practical and research gaps, this study aims to develop a PYD model suitable for …

“The People Deserve Better Governance”: Examining The Letters Of Filipino High School Students To The Next President Of The Philippines, Ma. Glenda Lopez Wui, Jessica Sandra R. Claudio, Rosselle Trishia M. Reyes, Carl Russel R. Reyes, Jie Zhang, Enrique Niño P. Leviste

Asia-Pacific Social Science Review

The study examined the results of the civic writing project “Letter to the Next President of the Philippines,” where grades 9-10 students were asked to write a letter to the next president about social problems that they wanted their future leader to resolve and why. The study analyzed the students’ letter topics according to their school type and location, gender, and the students’ sources of information for their civic writing. The letters (N=322) were written by students from urban and rural, and public and private schools across the country in March-May 2022 before the Philippine presidential election. The quantitative analysis …

Sustainable Cities In Developing Countries: A Case Of Balancing Cultural Heritage Preservation And Tourism In Manila, Philippines, Geoffrey Rhoel C. Cruz, Ma. Divina Gracia Z. Roldan

Asia-Pacific Social Science Review

This study argues that heritage can work side-by-side with development, with culture and heritage serving as an integral part of the city’s economic backbone. A major challenge faced by developing countries is making their cities sustainable by preserving cultural heritage amidst demands for economic growth. This is experienced in the Philippines, with its capital city, Manila, as a case in point. Using a heritage-driven development framework developed by Zerrudo (2020), the paper examines how cultural heritage conservation and tourism development objectives affect the sustainability of cities in developing countries. The paper emphasizes culture as an important pillar of sustainable development. …

Development And Validation Of The Malaysia Cybervictimization Scale For Adolescents In Malay And Chinese Version, Poh Chua Siah, Xiang Yi Tee, Chee-Seng Tan, Joanna Tjin Ai Tan, Komathi Lokithasan, Sew Kim Low, Chin Choo Yap

Asia-Pacific Social Science Review

The increasing rate of cybervictimization has been documented in various countries, including Malaysia. However, there is a dearth of measurement tools with sound psychometric properties suitable for the Malaysian context. To address this methodological gap, the Malaysia Cybervictimization Scale for Adolescents (MyCVS-A) was developed based on qualitative inputs from adolescents in Malaysia. It was subsequently translated into Malay (MyCVS-A-M) and Chinese (MyCVS-A-C). Two studies were conducted to examine the psychometric properties of these two translated versions. In Study 1, 281 secondary school students completed the MyCVS-A-M, the Malay version of the cybervictimization subscale of the European Cyberbullying Intervention Project Questionnaire …

Metagenomic Analysis Of Bacterial Communities In Waters Of Lake Natron, Arusha, Tanzania, Sadikiel E. Kaale, Robert S. Machang’U, Thomas J. Lyimo

Tanzania Journal of Science

Metagenomics involves genetic material extraction and sequencing directly from environmental samples in order to gain insights and relationships that exist between microbes and their surroundings. Few studies have been done in extreme environments including soda lakes such as Lake Natron which is found in Arusha region, Tanzania. This study recorded high pH and salinity values confirming the lake's extremity. Full-length 16S rRNA reads sequenced through PacBio was used to reveal first metagenomic snapshots of bacterial communities from 10 random points at the lake shoreline waters. The results showed the dominance of Proteobacteria and Firmicutes with relative abundances of 98.46% and …

Disruption Of Distal Appendage Protein Cep164 Causes Skeletal Malformation In Mice, Hiroyuki Yamaguchi, Megumi Kitami, Margaret Li, Sowmya Swaminathan, Radbod Darabi, Ken-Ichi Takemaru, Yoshihiro Komatsu

Faculty, Staff and Student Publications

The primary cilium is a cellular antenna to orchestrate cell growth and differentiation. Deficient or dysfunctional cilia are frequently linked to skeletal abnormalities. Previous research demonstrated that ciliary proteins regulating axoneme elongation are essential for skeletogenesis. However, the role of the ciliary proteins responsible for initiating cilium assembly in skeletal development remains unknown. Here, we investigate the function of centrosomal protein of 164 kDa (CEP164), a key ciliogenesis regulator that localizes at the distal appendages of the mother centriole, during skeletal development in mice. Interestingly, the mesodermal cell-specific Cep164 deletion resulted in severe bone defects and osteoblast-specific deletion of Cep164 …

Saponin Tql1055 Adjuvant-Containing Vaccine Confers Protection Upon Mycobacterium Tuberculosis Challenge In Mice, Mushtaq Ahmed, Eric Farris, Rosemary V Swanson, Shibali Das, Yan Yang, Tyler Martin, Shabaana A Khader

2020-Current year OA Pubs

Tuberculosis (TB), caused by the intracellular pathogen

Head-To-Head Comparison Of Aptamer- And Antibody-Based Proteomic Platforms In Human Cerebrospinal Fluid Samples From A Real-World Memory Clinic Cohort, Raquel Puerta, Yun Ju Sung, Carlos Cruchaga, Et Al.

2020-Current year OA Pubs

High-throughput proteomic platforms are crucial to identify novel Alzheimer's disease (AD) biomarkers and pathways. In this study, we evaluated the reproducibility and reliability of aptamer-based (SomaScan

Automated Differentiation Of Wide Qrs Complex Tachycardia Using Qrs Complex Polarity, Adam M May, Bhavesh B Katbamna, Preet A Shaikh, Sarah Lococo, Elena Deych, Ruiwen Zhou, Lei Liu, Krasimira M Mikhova, Rugheed Ghadban, Phillip S Cuculich, Daniel H Cooper, Thomas M Maddox, Peter A Noseworthy, Anthony Kashou

2020-Current year OA Pubs

BACKGROUND: Wide QRS complex tachycardia (WCT) differentiation into ventricular tachycardia (VT) and supraventricular wide complex tachycardia (SWCT) remains challenging despite numerous 12-lead electrocardiogram (ECG) criteria and algorithms. Automated solutions leveraging computerized ECG interpretation (CEI) measurements and engineered features offer practical ways to improve diagnostic accuracy. We propose automated algorithms based on (i) WCT QRS polarity direction (WCT Polarity Code [WCT-PC]) and (ii) QRS polarity shifts between WCT and baseline ECGs (QRS Polarity Shift [QRS-PS]).

METHODS: In a three-part study, we derive and validate machine learning (ML) models-logistic regression (LR), artificial neural network (ANN), Random Forests (RF), support vector machine (SVM), …

Supporting Teams With Designing For Dissemination And Sustainability: The Design, Development, And Usability Of A Digital Interactive Platform, Maura M Kepper, Allison J L'Hotta, Thembekile Shato, Bethany M Kwan, Russell E Glasgow, Douglas Luke, Andrea K Graham, Ana A Baumann, Ross C Brownson, Brad Morse

2020-Current year OA Pubs

BACKGROUND: Designing for Dissemination and Sustainability (D4DS) principles and methods can support the development of research products (interventions, tools, findings) that match well with the needs and context of the intended audience and setting. D4DS principles and methods are not well-known or used during clinical and public health research; research teams would benefit from applying D4DS. This paper presents the development of a new digital platform for research teams to learn and apply a D4DS process to their work.

METHODS: A user-centered design (UCD) approach engaged users (n = 14) and an expert panel (n = 6) in an iterative …

Impact Of Helminth Co-Infections On Clinical Malaria Severity Among Febrile School-Age Children: A Study From Mvomero, Tanzania, Winifrida Kidima, Christopher Kisiringo, Deokary Matiya, Felista Mwingira

Tanzania Journal of Science

Helminths may influence clinical malaria severity. The current study examined the impact of helminth infections on malaria severity among children in Mvomero, Tanzania. This was a hospital-based cross-sectional study conducted from 2018-2019. Blood, stool and urine specimens from febrile subjects attending four health facilities in Mvomero were examined for malaria and helminth infection. Overall, 326 febrile children were enrolled. The range and mean ages were 5-17 and 10.2 years, respectively. Of 326 children, 46.8% (n = 153) had Plasmodium falciparum malaria, with prevalence being higher in males than females (p = 0.03). Among positive P. falciparum -infected children, 59.5% had …

Spatio-Temporal Trends And Change Detection Of Surface Air Temperature In Tanzania: October To April Season., Laban Lameck Kebacho, Exavery Kisesa Makula, Paul Tilwebwa Shelleph Limbu

Tanzania Journal of Science

The paper examined the spatio-temporal variability and trends of minimum temperature (T-min), mean (T-mean), and maximum temperature (T-max) in Tanzania from October to April using the Climatic Research Unit Time Series version 4.06 from 1951-2021. The traditional Mann-Kendall (MK) test, modified MK, and Sen’s slope test were used to determine the trend direction and magnitude of the T-mean, T-max, and T-min trends, respectively. Sequential MK, standard normal homogeneity, and Pettitt tests were used to detect abrupt changes, while the Hurst coefficient (H) assessed future trend behavior. Results show a statistically significant increasing trend of 0.14 °C per decade, 0.18 °C …

Length-Weight Relationship And Condition Factor Of Three Cichlids From The Tono Dam, Ghana, Emmanuel O. Kombat, Elijah D. Angyiereyiri, Sandra A. Atindana, Elliot H. Alhassan

Tanzania Journal of Science

The length-weight relationship (LWR) and condition factor of three Cichlids, namely, Sarotherodon galilaeus, Coptodon zillii and Oreochromis niloticus from the Tono dam in Ghana, were investigated. A total of 1,870 individuals of the target species were randomly collected from 20 artisanal fishermen using gill nets to fish from January to December 2015. Each species was sorted by sex, and each fish's total length (L) and body weight (W) were measured and recorded. Simple linear regression plots of weight against length were computed, and the slope of the regression line, ‘b’ and intercept of the regression line, ‘a’ of each species …

Becoming Connective: Strengthening Diversity In Nursing Education, Melanie Jacobs

Electronic Theses and Dissertations Archive

Abstract Diversity in the nursing profession does not match the demographic of patients in the United States and correcting this mismatch could positively impact health disparities in the country. This post-intentional phenomenological study examines the current relationship between nursing education, as the pipeline into the profession, and students from underrepresented racial and ethnic (URRE) groups in the nursing profession to offer movement into the development of a stronger connection. In this qualitative study, phenomenological and poststructural tenets were used to seek the phenomenon of becoming connective, the creative tendency toward connection between URRE and nursing education. Data were generated from …

Rdn Diagnosed Malnutrition At St. Jude Children’S Research Hospital: Onset To Resolution Using And/Aspen Criteria, Madison Domek

Electronic Theses and Dissertations Archive

This quality improvement (QI) project investigates the incidence and management of malnutrition in pediatric oncology patients at St. Jude Children’s Research Hospital (SJCRH) from October 2022 to September 2023. The study aims to quantify malnutrition diagnoses made by registered dietitian nutritionists (RDNs) and to identify patients at higher risk of severe malnutrition based on their primary cancer diagnosis and clinic location. A total of 161 patients were identified, resulting in 238 documented instances of malnutrition, classified as mild, moderate, or severe. The majority of unresolved cases were attributed to inadequate follow-up, particularly in the Hematology Clinic, which had a 100% …