Digital Commons Network^™

Dynamic And Concordance-Assisted Learning For Risk Stratification With Application To Alzheimer’S Disease, Wen Li, Ruosha Li, Ziding Feng, Jing Ning

Faculty, Staff and Student Publications

Dynamic prediction models capable of retaining accuracy by evolving over time could play a significant role for monitoring disease progression in clinical practice. In biomedical studies with long-term follow up, participants are often monitored through periodic clinical visits with repeat measurements until an occurrence of the event of interest (e.g. disease onset) or the study end. Acknowledging the dynamic nature of disease risk and clinical information contained in the longitudinal markers, we propose an innovative concordance-assisted learning algorithm to derive a real-time risk stratification score. The proposed approach bypasses the need to fit regression models, such as joint models of …

Rural Volunteer Emergency Personnel’S Perceptions Of Stressors During The Covid-19, Janette Lynn Nichols, Phd

Walden Dissertations and Doctoral Studies

Emergency personnel are expected to handle all situations without affecting their psyche. Distinct differences exist between urban and rural EMS personnel, with rural personnel frequently needing more organizational resources or support to manage stress. With the onset of COVID-19 in December 2019, rural emergency personnel were placed in exhaustive specific situations not experienced previously within the United States. This study was conducted to focus on how they internalize their stressors. This generic qualitative study aimed to determine the perceptions of stressors experienced by rural volunteer emergency personnel during the COVID-19 pandemic. A qualitative survey was completed by 11 participants who …

College Student-Athlete Perceptions Of Characterizations And Interpersonal Trust In Their Athletic Trainer: A Point-Of-Care Research Study, Ryan N. Moran, Deidre Leaver-Dunn, Jeff Allen, Jessica Wallace

Clinical Practice in Athletic Training

Patient-centered care is essential in athletic training with limited research examining the relationship between patient and clinician. Previous theory has identified constructs of quality athletic trainers (ATs); however, it remains unknown how current athletes perceive these theorized constructs in the ATs providing them medical care. The purpose of this study was to determine the perceptions of characterizations of a quality athletic trainer and interpersonal trust between the student-athlete and AT in the collegiate setting and establish reliability of these surveys. A second aim was to explore differences between sex, previous exposure to an AT, and having had access to an …

The Impact Of Video-Assisted Education On Knowledge And Retention Compared To Paper Education Material, Keiona M. Nance, Matthew J. Drescher, Lindsey E. Eberman, Matthew J. Rivera

Clinical Practice in Athletic Training

When educating patients, clinicians must be effective to assure patients understand their treatment plan and abide by such to achieve optimal outcomes. Teaching methods that stimulate numerous senses more positively impact learning outcomes. The purpose of this study is to compare paper and video-assisted education at the point-of-care with the aim of changing patient education and local practice in a system for individuals undergoing total hip arthroplasties (THAs). We used a randomized cohort design to explore patient knowledge and retention and educational method at the point-of-care. We compared the current education method (paper) to video-assisted materials using pre and post-education …

Exploratory Clinical Assessment And Treatment Of Autonomic Nervous System Dysregulation Post Concussion: A Case Study, Megan Coker, James May

Clinical Practice in Athletic Training

The physiological alterations in autonomic nervous system (ANS) function due to concussion are suggested to play a role in persistent post-concussion symptoms (PPCS). Currently, there are few objective and clinically feasible measurements to assess ANS vitality in patients experiencing PPCS. The following case study details an assessment and treatment protocol targeted towards regulating the ANS in an adolescent female suffering from PPCS one month after injury. Pre-intervention, patient-reported outcome measures (PROMs) used to assess perceived pain, anxiety, stress, and breathing function were administered as well as a physical assessment performed for breath function and vagus nerve integrity. The patient was …

Comparing Mental Health Between Ncaa Division Iii Student-Athletes Competing In Team- And Individual-Sports, Autumn Presley, Tiffany Franklin, Jeffrey Williams

Clinical Practice in Athletic Training

Mental health is a topic that has gained attention in recent years, but few studies have examined NCAA Division III student-athletes. Division III student-athletes are known to experience high levels of distress, and previous literature indicates there may be a significant psychological difference between student-athletes who compete in individual-sports compared to those who participate in team-sports. The purpose of this study was to explore mental health challenges (levels of depression, stress, and anxiety symptoms) among Division III student-athletes, particularly between those participating in team- and individual-sports. A cross-sectional survey design was used. The independent variable was group (team-sport athletes and …

Medical Disqualification As A Barrier To Healthcare In Military Service Members, Kaitlyn A. Jones, Joshua R. Jaime, Zachary K. Winkelmann

Clinical Practice in Athletic Training

N/a

2024 - Tennessee Annual Climate Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Monthly Reports

No abstract provided.

Ai-Assisted Academia: Unveiling Doctoral Students' Perspectives On Dissertation In Practice Innovation, Jennifer J. Lesh, Jévaughn J. Lancaster

Faculty and Staff Publications & Presentations

This action research study explores 73 doctoral students' perceptions of using Generative Artificial Intelligence (GAI) throughout their research journey in one educational doctorate (Ed.D) program. The first phase employed surveys, while the second incorporated semi-structured focus group interviews based on the survey data from a diverse sample of students across educational disciplines currently enrolled in the university's educational leadership doctoral program. In the study's first phase, the survey quantified educators' familiarity with, attitudes towards, perceived challenges, ethical considerations, and benefits of using GAI in doctoral research. The exploration of GAI in this practitioner-inspired doctoral program has uncovered essential insights into …

Advancing Statistical Literacy In Eye Care: A Series For Enhanced Clinical Decision-Making: Part 1: Introduction To Statistical Tools For Eye Care Research, Daniela Oehring, Pedro Miguel Serra

School of Health Professions

Purpose. Advancements in eye and vision care hinge on therigorous application of research and the precise interpretationof clinical data. However, the field of Eye and Vision Research(EVR) frequently encounters research waste attributed tomethodological flaws and improper statistical analyses, un-dermining the validity of studies and inefficiently utilisingsubstantial financial resources. This paper, the first instalmentin the series “Advancing Statistical Literacy in Eye Care: A Se-ries for Enhanced Clinical Decision-Making,” aims to addressthese challenges by enhancing the statistical literacy of eyecare professionals.Material and Methods. Through a comprehensive narrativeliterature review and the generation of simulated clinicaldatasets, this study identifies essential statistical concepts,common pitfalls, and …

Educating Mental Healthcare Staff On Using The Phq-9 In Telehealth, Anoopa M. Jacob

Walden Dissertations and Doctoral Studies

I developed a quality improvement staff educational program aimed at addressing the inconsistent use of the Patient Health Questionnaire (PHQ-9) at the project facility, which could adversely affect the quality and continuity of patient care. The need for the program was prompted by the increasing use of telehealth services and the necessity for consistent mental health evaluation tools. I aimed to educate mental health staff about evidence-based practices using the PHQ-9 in telehealth to enhance the quality of care for patients with depression in remote settings. Analytical methods included administering pre- and postintervention tests to measure changes in staff knowledge …

An Interview With Sharon Lee Hart, Mysoon Rizk, Sharon Lee Hart

Art Inquiries

No abstract provided.

A Bayesian Pharmacokinetics Integrated Phase I-Ii Design To Optimize Dose-Schedule Regimes, Mengyi Lu, Ying Yuan, Suyu Liu

Faculty, Staff and Student Publications

The schedule of administering a drug has profound impact on the toxicity and efficacy profiles of the drug through changing its pharmacokinetics (PK). PK is an innate and indispensable component of the dose-schedule optimization. Motivated by this, we propose a Bayesian PK integrated dose-schedule finding (PKIDS) design to identify the optimal dose-schedule regime by integrating PK, toxicity, and efficacy data. Based on the causal pathway that dose and schedule affect PK, which in turn affects efficacy and toxicity, we jointly model the three endpoints by first specifying a Bayesian hierarchical model for the marginal distribution of the longitudinal dose-concentration process. …

Neurofilament Light Chain In Serum Of Cancer Patients With Acute Neurological Complications, Amulya Gottiparthy, Keng Lam, Suprateek Kundu, Zixi Yang, Ivo Tremont-Lukats, Sudhakar Tummala

Faculty, Staff and Student Publications

Aim: Neurofilament light chain (NfL) is a nonspecific sensitive biomarker of axonal damage.

Methods: This case series identified cancer patients with neurological complications who had serum NfL measurements and paired these results to outcomes.

Results: NfL serum levels were available in 15 patients with hematological malignancies or solid tumors. The neurological complications studied were immune effector cell-associated neurotoxicity syndrome, immune checkpoint inhibitor-related encephalopathy, anoxic brain injury, Guillain-Barre syndrome, hemophagocytic lymphohistiocytosis, transverse myelitis, paraneoplastic syndrome, central nervous system demyelinating disorder and chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. All patients but one with serum NfL >900 pg/ml died …

Predicting Kidney Graft Function And Failure Among Kidney Transplant Recipients, Yi Yao, Brad C Astor, Wei Yang, Tom Greene, Liang Li

Faculty, Staff and Student Publications

Background: Graft loss is a major health concern for kidney transplant (KTx) recipients. It is of clinical interest to develop a prognostic model for both graft function, quantified by estimated glomerular filtration rate (eGFR), and the risk of graft failure. Additionally, the model should be dynamic in the sense that it adapts to accumulating longitudinal information, including time-varying at-risk population, predictor-outcome association, and clinical history. Finally, the model should also properly account for the competing risk by death with a functioning graft. A model with the features above is not yet available in the literature and is the focus of …

Quantitative Risk Assessment In Thermo-Chemical Waste-To-Energy Facilities, Fakhrul R. Ridzwan, Syaza Izyanni Ahmad

Platform: A Journal of Engineering (PAJE)

This study presents a Quantitative Risk Assessment (QRA) of thermo-chemical Waste-to-Energy (WtE) technologies, specifically incineration and gasification, by utilising simulation tools PHAST and SAFETI. Hazard identification, consequence analysis, and risk assessment were conducted to compare the safety profiles of these two technologies and proposed risk reduction strategies for a safer design. Accident scenarios were modelled for Tuas South Incineration and Borregaard Gasification facilities to analyse dispersion and effects of fire and explosion. Hazards indicated that only gasification exclusively involves flammable releases because it reacts as a partial combustion, with carbon monoxide and hydrogen as flammable byproducts. Results revealed that while …

Implications Of Myocardial Strain In Primary Mitral Regurgitation-A Cardiovascular Magnetic Resonance Study, Simone Romano, Danai Kitkungvan, Duc T Nguyen, Carlos El-Tallawi, Edward A Graviss, Afshin Farzaneh-Far, Dipan J Shah

Faculty, Staff and Student Publications

Aims: Chronic primary mitral regurgitation (MR) results in progressive left ventricular (LV) remodelling. Abnormal myocardial deformation (strain) can be present despite preserved ejection fraction (EF). Cardiovascular magnetic resonance (CMR) feature-tracking techniques allow assessment of global longitudinal strain (GLS) from routine cine images. The aim of this study is to evaluate the prognostic value of CMR feature tracking-derived GLS in patients with primary MR.

Methods and results: Consecutive patients undergoing CMR for chronic MR from January 2012 to June 2018 were enrolled. Patients with LVEF < 50% were excluded. The composite primary outcome aiming to detect decompensation related to MR comprised (i) referral for mitral surgery owing to symptoms or LV systolic dysfunction or (ii) cardiovascular death. The secondary outcome was all-cause death. A total of 422 patients were followed for a median of 2.7 years, and the primary endpoint was met in 93 patients (34 patients reported symptoms at baseline). At multivariable analysis, GLS≥ -16.6% was associated with primary outcome [hazard ratio (HR) 1.90, P = 0.01]. In moderate MR cohort, patients with GLS≥ -16.6% had worse event-free survival, whereas there was no significant difference in mild or severe MR groups. GLS≥ -16.0% remained associated with all-cause death after adjusting for other covariates including the MR severity (HR 2.24, P = 0.02).

Conclusion: In patients with primary MR with preserved systolic function, GLS was associated with our composite …

Implementation Of Patient Care Documentation Standard For Athletic Training Staff In Intercolle, Lucas Bianco, Maria Popek, Bri Durics, Christian Miles

Clinical Practice in Athletic Training

Documentation is a professional standard for all health care professions. As part of a relatively young profession, athletic trainers have had to adjust to the expectations around documentation to stay at the same level as other health care providers. Documentation is often a highly discussed topic with more and more education sessions and resources being provided by NATA, BOC and NATA Research Education Foundation. The need for Continuous Quality Improvement projects and subsequent studies has continued to grow. Projects with a focus on documentation can be completed then disseminated to determine the most effective ways to improve documentation across our …

Acute Myocarditis Secondary To Human Metapneumovirus: A Case Series And Mini-Review, Hussam Al Hennawi, Aamna Khan, Alexander Shpilman, Jennifer A. Mazzoni

Abington Jefferson Health Papers

Among viral myocarditis, human metapneumovirus (hMPV) is a rare causative agent with associated cardiac complications. This report provides insight into the disease progression and sheds light on reported cases from the literature. We present the clinical courses of two patients, aged 68 and 58, who developed myocarditis secondary to hMPV infection. Despite the typical severity associated with viral myocarditis in older populations, both patients experienced significant improvement in their condition and ultimately survived. This report highlights the necessity of recognizing hMPV as a potential cause of myocarditis, particularly in older adults presenting with simultaneous respiratory and cardiac symptoms. The recovery …

Daddy Goggles, Mason J. Rohr

Graduate Medical Education Research Journal

N/A

Accelerating The Uptake Of Home Haemodialysis: An Evidence-Informed Implementation Project In Cornwall, Emmanuel Asimah

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Exploring The Factors Influencing Retention Of Internationally Educated Nurses At Torbay And South Devon Nhs Foundation Trust: A Service Improvement Project, Abdul-Manan Alhassan

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Home Treatment Team Response For People With Complex Emotional Difficulties: Evidence Informing Service Development, Chloe Parkin, Lauren Oliver, Yasemin Demir

South West Clinical School Journal

#400WORDS: KNOWLEDGE + ACTION

Identifying The Key Factors For Education During Physiotherapy Treatment Of Patients With Frozen Shoulder: Developing An Educational Intervention, Laura Tapp

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

Repeated Bed Moves In A Community Treatment And Assessment Unit (Catu), Exploring The Impact On Patients And Nursing Staff, Erica Simmonds

South West Clinical School Journal

#400WORDS: CHIEF NURSING OFFICER’S RESEARCH FELLOWS EVIDENCE IMPLEMENTATION PROJECTS

The Role Of Interactive Control Systems In Strengthening Esg Practices And Investment Efficiency: Mcs-Loc Insights, Idrianita Anis, Regina Jansen Arsjah, Hartini Hartini

Jurnal Akuntansi dan Keuangan Indonesia

This research aims to develop an Environmental, Social, and Governance (ESG) practices model and index based on sustainable finance regulation from a Management Control System Four Levers of Control (MCS-LoC) perspective. The ESG index was developed by utilizing content analysis of information disclosure in annual and sustainability reports of ten non-financial industry sectors listed in the Indonesia Stock Exchange from 2015 to 2022 (640 observations). Subsequently, the effect of the ESG Index on Investment Efficiency (IE) was tested with the moderating role of Interactive Control (INTR). The results indicate that companies are in the second stage of the sustainable business …

Behavioral Accounting As A Catalyst In The Organizational Transformation Process Toward Sustainability, Ni Wayan Yellow Prinsis Dayani, I Gusti Ayu Nyoman Budiasih

Jurnal Akuntansi dan Keuangan Indonesia

This research investigates the role of behavioral accounting as a catalyst in the organizational transformation process towards sustainability using phenomenological methods. The study aims to explore how behavioral accounting identifies individual behavioral factors, designs efficient sustainability systems, and enhances organizational commitment to sustainable practices. The research employs observation, secondary data analysis, and semi-structured interviews with organizational internal team, analyzed through Interpretative Phenomenological Analysis (IPA). Findings indicate that behavioral accounting contributes to organizational sustainability by enhancing transparency in accounting information, thereby minimizing the risk of fund misuse and ensuring efficient resource allocation. This research supports behavioral accounting as pivotal in shaping …

Transcriptomic Profile Analysis Of Brain Tissue In The Absence Of Functional Trpm8 Calcium Channel, Erick B Saldes, Alexandra Erdmier, Jai Velpula, Timothy E Koeltzow, Michael X Zhu, Swapna Asuthkar

Faculty, Staff and Student Publications

Background/Objectives: Transient Receptor Potential Melastatin 8 (TRPM8) is a non-selective, Ca2+-permeable cation channel involved in thermoregulation and other physiological processes, such as basal tear secretion, cell differentiation, and insulin homeostasis. The activation and deactivation of TRPM8 occur through genetic modifications, channel interactions, and signaling cascades. Recent evidence suggests a significant role of TRPM8 in the hypothalamus and amygdala related to pain sensation and sexual behavior. Notably, TRPM8 has been implicated in neuropathic pain, migraines, and neurodegenerative diseases such as Parkinson's disease. Our laboratory has identified testosterone as a high-affinity ligand of TRPM8. TRPM8 deficiency appears to influence behavioral traits in …

Hubungan Antara Hipertensi Dan Kematian Pasien Covid-19 Di Layanan Rawat Inap Rsud Tarakan Tahun 2022 (Association Between Hypertension And Mortality Of Covid-19 Inpatients At Tarakan Regional General Hospital In 2022), Karina Widyasari, Mondastri Korib Sudaryo

Jurnal Epidemiologi Kesehatan Indonesia

Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 was the leading disease in terms of the highest number of hospital admissions and cause of death at the Tarakan Regional General Hospital (RSUD Tarakan) in 2022. COVID-19 patients who received treatment at the hospital were often individuals with underlying conditions, such as hypertension. Therefore, it is important to conduct research on comorbidities, specifically hypertension, and its relationship to COVID-19 mortality at the RSUD Tarakan’s inpatient in 2022, so the hospital can design spesific care plans for COVID-19 patients with hypertension. …

Faktor-Faktor Yang Berhubungan Dengan Asfiksia Neonatus: Studi Kasus Kontrol Di Rsud Kabupaten Serang, Banten, Indonesia, Husnul Khotimah, Yosi Yusrotul Khasanah, Nur Arofah

Jurnal Epidemiologi Kesehatan Indonesia

Asphyxia in newborns is a common and serious cause of neonatal morbidity and mortality nationally and internationally. Risk factors for asphyxia can be seen from maternal and infant factors. The purpose of this study was to determine the risk factors in mothers and infants and to analyze which factors have the most influence on asphyxia. This study is a quantitative analytical study with a case-control approach. The number of case samples was 53 infants who experienced asphyxia and 53 control (1:1) infants so that the total sample was 106 infants. The variables studied were parity, Low Birth Weight (LBW), preeclampsia, …