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Online Parameter Adaptation Of Lqr Controllers Via Rls For Prosthetic Joint Control: Experimental Validation On A Quanser Qube-Servo 2 Platform, Cynthia Lopez-Jordan Jan 2025

Online Parameter Adaptation Of Lqr Controllers Via Rls For Prosthetic Joint Control: Experimental Validation On A Quanser Qube-Servo 2 Platform, Cynthia Lopez-Jordan

Theses and Dissertations

This thesis develops and experimentally validates an online adaptive Linear Quadratic Regulator (LQR) control method for prosthetic joint systems using Recursive Least Squares (RLS)-based real-time parameter estimation on the Quanser QUBE-Servo 2 platform. Traditional LQR controllers assume a fxed system model, which limits adaptability and results in reduced tracking accuracy, poor robustness, and loss of optimal performance when applied to dynamically changing prosthetic joints, infuenced by load variations, user gait changes, and mechanical wear. Limited experimental validation exists for combining RLS with online LQR adaptation in prosthetic-like systems.

To address these limitations, an RLS-driven Adaptive LQR framework was implemented to …


From Curiosity To Controversy: American Perception Of Japanese Immigrants, 1853-1924, Chloe Elizabeth Curbelo Jan 2025

From Curiosity To Controversy: American Perception Of Japanese Immigrants, 1853-1924, Chloe Elizabeth Curbelo

Theses and Dissertations

In the mid-nineteenth century, as the United States reached the Pacific through westward expansion, Asia emerged as a new stage for commerce and power. Japan, long isolated under the Tokugawa shogunate, became an object of American fascination when forced into relations. While early depictions cast Japan as an exotic yet uncivilized nation in need of Western guidance, Japan’s rapid modernization and the growing number of Japanese immigrants on the West Coast transformed curiosity into anxiety. My paper traces this evolution of perception from 1850 to 1924, arguing that shifting views of Japan and its people reflected America’s ethnocentric notions of …


Estrogen Receptor-Mediated Effects Of Resveratrol On Muscle Function, David Ayi-Bonte Jan 2025

Estrogen Receptor-Mediated Effects Of Resveratrol On Muscle Function, David Ayi-Bonte

Open Access Master's Theses

Artemis missions are set to send the next man and the first woman back to the moon and enable long-term missions on the lunar surface. However, exposure to lunar gravity has significant physiological effects characterized by loss of muscle mass, weakness and decreased bone density. Nutraceutical countermeasures such as Resveratrol (RSV), a naturally occurring polyphenol, have been identified as promising strategies to preserve musculoskeletal health; however, its pleiotropic effect hinders our ability to identify the primary cellular pathways through which it delivers its benefits. Furthermore, its efficacy in simulated lunar gravity is unknown. Based on the benefits observed with RSV …


Leads Data Insights: Discovery — January 2025, University Of North Dakota Jan 2025

Leads Data Insights: Discovery — January 2025, University Of North Dakota

LEADS Development Documents

January 2025 Data Insights presentation for the DISCOVERY core value of UND LEADS. The slides review Discovery-related Activity Inventory coverage and summarize data on HERD research expenditures, undergraduate research involvement, graduate degree conferrals, Grand Challenge research awards, and sponsored-program partnerships.


“Democracy,” Usa, Marc Edelman Jan 2025

“Democracy,” Usa, Marc Edelman

Publications and Research

What does it mean to be an effective citizen in a democracy? Answering this question requires unpacking “democracy” and an analysis of institutions that systematically disempower and alienate citizens. This paper briefly examines the contributions of psychoanalysis to understanding democracy and authoritarianism. It scrutinizes U.S. governance institutions and points to democratic deficits and backsliding present even before Trump 1.0 and 2.0. These range from the Electoral College, the Senate, and the Supreme Court to the Federal Communications Commission. All contributed to institutionalizing minority rule and elite capture. Governance institutions failed to deliver what the American people tell opinion pollsters they …


Improving System-Level Outcomes Via Artificial Intelligence Decision Support In Kidney Utilization, Casey I. Canfield, Cihan H. Dagli, Daniel Burton Shank, Krista Lentine, Mark Schnitzler, Henry Randall, V. Sriram Siddhardh Nadendla, Brendon Cummiskey Jan 2025

Improving System-Level Outcomes Via Artificial Intelligence Decision Support In Kidney Utilization, Casey I. Canfield, Cihan H. Dagli, Daniel Burton Shank, Krista Lentine, Mark Schnitzler, Henry Randall, V. Sriram Siddhardh Nadendla, Brendon Cummiskey

Engineering Management and Systems Engineering Faculty Research & Creative Works

Transplantation provides patients suffering from end-stage kidney disease a better quality of life and long-term survival. However, over 20% of deceased donor kidneys are not utilized and never transplanted. While this is sometimes medically appropriate, this also reflects missed opportunities. We are designing Artificial Intelligence decision support for the kidney offer process to support both demand at the transplant center and supply at the organ procurement organization. This includes (1) developing deep learning models, (2) evaluating the effect of explainable interfaces, (3) improving fairness in the model output, (4) identifying factors that influence adoption decisions, and (5) conducting a randomized …


Augmenting Missing Sensor Data For Robust Human Activity Recognition, Suryakangeyan Kandasamy Gowdaman Jan 2025

Augmenting Missing Sensor Data For Robust Human Activity Recognition, Suryakangeyan Kandasamy Gowdaman

Master's Projects

Applications of ubiquitous computing, including health monitoring, sports analytics, and ambient-assisted living, rely on Human Activity Recognition (HAR) using wearable sensors. However, model robustness is challenged by missing sensor values, class imbalance, inter-subject variability, and temporal noise. This work proposes a complete HAR pipeline that addresses these challenges through sampling, time-series augmentation, dynamic feature handling, and GAN-PCA-based imputation. Built on the DeepSense architecture, the model integrates convolutional feature extraction with bi-GRUs for temporal modeling. The system is evaluated using 5-fold cross-validation, subject-aware holdout, and LOSEO strategies on the Opportunity dataset. Results demonstrate consistent accuracy across folds and strong generalization to …


Energy Considerations For Large Pre-Trained Neural Networks, Leo Mei Jan 2025

Energy Considerations For Large Pre-Trained Neural Networks, Leo Mei

Master's Projects

In recent years, neural network models have achieved phenomenal performance due to the increasing parameters and complexity of model architectures. However, these advancements come with high environmental costs as they require massive computational resources and consume substantial amounts of electricity, leading to high carbon emissions. Previous studies have demonstrated that substantial redundancies exist in large pre-trained models, and reducing these redundancies through compression would not compromise model performance. While these studies focused on retaining comparable model performance, the direct impact of compression on energy consumption when training models appears to have received little attention. By quantifying the energy usage associated …


Link Failure Localization In Hierarchical, Multidomain Optical Networks, Martin Mihailov Bojinov Jan 2025

Link Failure Localization In Hierarchical, Multidomain Optical Networks, Martin Mihailov Bojinov

Master's Projects

Optical networks transport data encoded on light signals over optical fiber cables. Individual optical networks are managed by domain administrators, such as service providers, vendors, or regional bodies. Multidomain optical networking explores the possibility of enabling seamless data transmission across domain boundaries. In this project, we explore how we can perform network monitoring in a hierarchical multidomain optical network while preserving domain security and autonomy. This is done by allocating dedicated monitoring trails across various broker abstractions of our network topologies. We propose three heuristic functions that expedite trail selection. Of the three heuristics, our least monitored algorithm performs the …


Suicidal Ideation Detection On Reddit Using Llm-Annotated Data And Graph Neural Networks, Ikbal Singh Gurdev Singh Dhanjal Jan 2025

Suicidal Ideation Detection On Reddit Using Llm-Annotated Data And Graph Neural Networks, Ikbal Singh Gurdev Singh Dhanjal

Master's Projects

Suicide is the fourth leading cause of death among people aged 15-29. More than 720, 000 people commit suicide every year. During the COVID-19 pandemic, we saw an increase in people seeking out mental health support on anonymous forums like Reddit. These anonymous forums allow people to express their suicidal ideation without judgment and give them a support structure that not everyone has. The aim of this project is to detect suicidal ideation using Reddit. In this work, we propose SIRGEL (Suicidal Ideation on Reddit using Graph Embeddings and LLMs), a dual-pipeline approach that combines large language model (LLM)- based …


Evaluation And Treatment Of Baseball Pitchers: There’S More To Assess Than The Arm, Matthew L. Gauthier, Casey A. Unverzagt, George J. Davies Jan 2025

Evaluation And Treatment Of Baseball Pitchers: There’S More To Assess Than The Arm, Matthew L. Gauthier, Casey A. Unverzagt, George J. Davies

Physical Therapy Faculty Publications

Injuries are commonplace in the overhead athlete, with many occurring to the shoulder and elbow. The increasing prevalence of injuries to the shoulder and elbow has been discussed at length in recent years, with increased research focus being placed on arm care for rehabilitation and prevention strategies. Even though the pitching motion is well-established as a whole-body kinetic chain movement, most attention in rehabilitation and prevention efforts is often placed on the upper extremity. The purpose of this clinical commentary is to highlight the impact the lower extremity and trunk have on the upper extremity during the throwing motion, better …


Arts-Integrated Mindfulness: Social-Emotional Learning For Elementary Education, Ashley J. M. Canny, Katherine A. Taylor Clausen, Amanda K. Cox, Bryce D. Cox Jan 2025

Arts-Integrated Mindfulness: Social-Emotional Learning For Elementary Education, Ashley J. M. Canny, Katherine A. Taylor Clausen, Amanda K. Cox, Bryce D. Cox

Graduate Research Papers

This action research investigates the impact of arts-integrated mindfulness practices on elementary students’ ability to self-regulate. In response to a significant rise in emotional dysregulation and mental health concerns among young learners - exacerbated by the COVID-19 pandemic - this study explores how combining mindfulness techniques with artistic expression can enhance emotional awareness, focus, and resilience. Through classroom activities such as breathing exercises, movement, music, and visual arts, students were guided to engage in self-reflection and emotion regulation in creative, accessible ways. Data collected through student surveys and observational records indicated that most participants experienced improved calmness, engagement, and readiness …


Depletion Of Adipose Stroma-Like Cancer-Associated Fibroblasts Potentiates Pancreatic Cancer Immunotherapy, Joseph Rupert, Alexes Daquinag, Yongmei Yu, Yulin Dai, Zhongming Zhao, Mikhail G Kolonin Jan 2025

Depletion Of Adipose Stroma-Like Cancer-Associated Fibroblasts Potentiates Pancreatic Cancer Immunotherapy, Joseph Rupert, Alexes Daquinag, Yongmei Yu, Yulin Dai, Zhongming Zhao, Mikhail G Kolonin

Faculty, Staff and Student Publications

This study shows that populations of CAFs have distinct effects on pancreatic cancer progression and shows that depletion of CAFs expressing adipose markers potentiates tumor/metastasis suppression effects of immune checkpoint blockade.


Tagraxofusp Maintenance Post-Hematopoietic Stem Cell Transplantation Provides Long-Term Survival And Manageable Safety For A Patient With Blastic Plasmacytoid Dendritic Cell Neoplasm, Qaiser Bashir, Marina Konopleva, Glorette Abueg, Jeremy Ramdial, Chitra Hosing, Samer A Srour, Amin Alousi, Uday R Popat, Yago Nieto, Gheath Alatrash, Richard E Champlin, Elizabeth J Shpall, Muzaffar Qazilbash, Naveen Pemmaraju Jan 2025

Tagraxofusp Maintenance Post-Hematopoietic Stem Cell Transplantation Provides Long-Term Survival And Manageable Safety For A Patient With Blastic Plasmacytoid Dendritic Cell Neoplasm, Qaiser Bashir, Marina Konopleva, Glorette Abueg, Jeremy Ramdial, Chitra Hosing, Samer A Srour, Amin Alousi, Uday R Popat, Yago Nieto, Gheath Alatrash, Richard E Champlin, Elizabeth J Shpall, Muzaffar Qazilbash, Naveen Pemmaraju

Faculty, Staff and Student Publications

Presented here is the case of a 68-year-old woman with blastic plasmacytoid dendritic cell neoplasm (BPDCN) treated with tagraxofusp (TAG) maintenance therapy post-allogeneic hematopoietic stem cell transplantation (allo-HCT). Prior to allo-HCT, the patient was treated with hydroxyurea and mini-CVD (cyclophosphamide, vincristine, and dexamethasone alternating with methotrexate (Methotrexate) and cytarabine) + venetoclax + TAG for 5 cycles, which induced morphologic complete remission with minimal residual disease. After allo-HCT, the patient had persistent cytogenic abnormalities 45,XX,der(7)add(7)(p13)del(7)(q11.2q22)add(7)(q32),add(12)(p13),-15,del(16)(q23),-17,+22,+2mar[1]/46,XX[19], and was then treated with TAG maintenance therapy at 9 mg/kg on a 28-day cycle for 16 cycles. At mid-treatment (cycle 6 of 16 cycles of …


Co-Morbid Indomethacin-Responsive Headaches In A Woman In Her Late 60s With Paroxysmal Hemicrania And Hypnic Headache: A Case Report, Ashlyn Brown, Randolph W Evans, Claudia Carrizo, Mark Burish Jan 2025

Co-Morbid Indomethacin-Responsive Headaches In A Woman In Her Late 60s With Paroxysmal Hemicrania And Hypnic Headache: A Case Report, Ashlyn Brown, Randolph W Evans, Claudia Carrizo, Mark Burish

Faculty, Staff and Student Publications

Paroxysmal hemicrania (PH) and hypnic headache (HH) are rare indomethacin-responsive headache syndromes. This case report details the new onset of both disorders in a woman in her late 60s. One headache type presented as severe pain centered on the right eyebrow, lasting 30 minutes, occurring more than 8 times daily, and associated with ipsilateral lacrimation and rhinorrhea. The second type was a right frontal severe pain, with onset at 4 a.m., occurring only during sleep, lasting 30 minutes, and with no associated factors. The patient's response to indomethacin for both headache types was confirmed through an unblinded ABAB study design: …


A Bayesian Deep Segmentation Framework For Glioblastoma Tumor Segmentation Using Follow-Up Mris, Tanjida Kabir, Kang-Lin Hsieh, Luis Nunez, Yu-Chun Hsu, Juan C Rodriguez Quintero, Octavio Arevalo, Kangyi Zhao, Jay-Jiguang Zhu, Roy F Riascos, Mahboubeh Madadi, Xiaoqian Jiang, Shayan Shams Jan 2025

A Bayesian Deep Segmentation Framework For Glioblastoma Tumor Segmentation Using Follow-Up Mris, Tanjida Kabir, Kang-Lin Hsieh, Luis Nunez, Yu-Chun Hsu, Juan C Rodriguez Quintero, Octavio Arevalo, Kangyi Zhao, Jay-Jiguang Zhu, Roy F Riascos, Mahboubeh Madadi, Xiaoqian Jiang, Shayan Shams

Faculty, Staff and Student Publications

Background: Glioblastoma (GBM) is the most common malignant brain tumor with an abysmal prognosis. Since complete tumor cell removal is impossible due to the infiltrative nature of GBM, accurate measurement is paramount for GBM assessment. Preoperative magnetic resonance images (MRIs) are crucial for initial diagnosis and surgical planning, while follow-up MRIs are vital for evaluating treatment response. The structural changes in the brain caused by surgical and therapeutic measures create significant differences between preoperative and follow-up MRIs. In clinical research, advanced deep learning models trained on preoperative MRIs are often applied to assess follow-up scans, but their effectiveness in this …


Examining Educational And Career Transition Points Among A Diverse, Virtual Mentoring Network, Erika L Thompson, Toufeeq Ahmed Syed, Zainab Latif, Katie Stinson, Damaris Javier, Gabrielle Saleh, Jamboor K Vishwanatha Jan 2025

Examining Educational And Career Transition Points Among A Diverse, Virtual Mentoring Network, Erika L Thompson, Toufeeq Ahmed Syed, Zainab Latif, Katie Stinson, Damaris Javier, Gabrielle Saleh, Jamboor K Vishwanatha

Faculty, Staff and Student Publications

Given the differences in trajectory for under-represented minorities in biomedical careers, we sought to explore how a virtual mentoring program, the National Research Mentoring Network (NRMN), and its platform (MyNRMN), may facilitate transitions in the science, technology, engineering, mathematics, and medicine (STEMM) pipeline. The purpose of this study was to describe how the size of an MyNRMN member’s mentoring network and level of engagement correlate with academic and career transitions. We examined MyNRMN platform user data from March 2020 to May 2021 (n = 2993). Logistic regression estimated the odds of a career or academic transition related to NRMN …


Key Considerations For Combination Therapy In Alzheimer’S Clinical Trials: Perspectives From An Expert Advisory Board Convened By The Alzheimer’S Drug Discovery Foundation, Jeffrey Cummings, Michael Gold, Mark Mintun, Michael Irizarry, Andrew Von Eschenbach, Suzanne Hendrix, Donald Berry, Cristina Sampaio, Kaycee Sink, Jaren Landen, Miia Kivipelto, Michael Grundman, Steven E Arnold, Allan Green, Katherine Partrick, Laura Nisenbaum, Aaron Burstein, Howard Fillit Jan 2025

Key Considerations For Combination Therapy In Alzheimer’S Clinical Trials: Perspectives From An Expert Advisory Board Convened By The Alzheimer’S Drug Discovery Foundation, Jeffrey Cummings, Michael Gold, Mark Mintun, Michael Irizarry, Andrew Von Eschenbach, Suzanne Hendrix, Donald Berry, Cristina Sampaio, Kaycee Sink, Jaren Landen, Miia Kivipelto, Michael Grundman, Steven E Arnold, Allan Green, Katherine Partrick, Laura Nisenbaum, Aaron Burstein, Howard Fillit

Faculty, Staff and Student Publications

There is growing consensus in the Alzheimer's community that combination therapy will be needed to maximize therapeutic benefits through the course of the disease. However, combination therapy raises complex questions and decisions for study sponsors, from preclinical research through clinical trial design to regulatory, statistical, and operational considerations. In January 2024, the Alzheimer's Drug Discovery Foundation convened an expert advisory board to discuss the key considerations in each of these areas. Experts agreed on the need to prioritize a combination therapy approach that encompasses a wide range of targets associated with aging and the underlying biology of Alzheimer's disease. Progress …


The Effects Of An Organizational Shift To Pay Transparency On Employees’ Justified Under-Met Pay Standing Expectations And Turnover Intentions, Heather Godsey Jan 2025

The Effects Of An Organizational Shift To Pay Transparency On Employees’ Justified Under-Met Pay Standing Expectations And Turnover Intentions, Heather Godsey

Industrial-Organizational Psychology Dissertations

Pay transparency is becoming more commonplace within U.S. organizations, due to the enactment of state pay transparency laws attempting to reduce the gender wage gap and broader calls for greater transparency in organizations. While transparency may be ideal, its effects on employee attitudes and behaviors are unclear. This study explored a potential unintended outcome of pay transparency, employee turnover, by examining how fairness perceptions mediate the justified under-met pay standing expectations and employees’ turnover intentions relationship, while investigating gender and justice sensitivity as moderators. A sample of 426 participants experienced an organizational shift from pay secrecy to pay transparency and …


A Change In Climate: Inclusion And Menopause Experience At Work, Janie D. Stuart Jan 2025

A Change In Climate: Inclusion And Menopause Experience At Work, Janie D. Stuart

Industrial-Organizational Psychology Dissertations

Inclusion within workplace environments is increasingly important as workforce diversity continues to expand. Despite anti-discrimination laws, women and other underrepresented groups often face exclusion in the workplace, which negatively affects their professional growth, health, and well-being. This research focused on how menopause, a natural biological transition, compounds workplace exclusion for women. Specifically, the study investigated the relationship between Menopause Experience and two workplace outcomes, Organizational Commitment and Turnover Intention, and assessed the moderating effects of Inclusion in organizations, teams, and non-gendered workplace cultures. There were strong positive relationships between all three dimensions of Inclusion with both Organizational Commitment and Turnover …


Annual Report, Associated Charities, Memphis, 1913 Jan 2025

Annual Report, Associated Charities, Memphis, 1913

Documents

Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1912 September 1 - 1913 September 1.


Annual Report, Associated Charities, Memphis, 1912 Jan 2025

Annual Report, Associated Charities, Memphis, 1912

Documents

First Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1911 December 22 - 1912 September 1.


Annual Report, Associated Charities, Memphis, 1917 Jan 2025

Annual Report, Associated Charities, Memphis, 1917

Documents

Sixth Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1916-1917.


Annual Report, Associated Charities, Memphis, 1914 Jan 2025

Annual Report, Associated Charities, Memphis, 1914

Documents

Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1913 September 1 - 1914 September 1.


Annual Report, Associated Charities, Memphis, 1918 Jan 2025

Annual Report, Associated Charities, Memphis, 1918

Documents

Seventh Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1917-1918.


Annual Report, Associated Charities, Memphis, 1916 Jan 2025

Annual Report, Associated Charities, Memphis, 1916

Documents

Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1915 September 1 - 1916 October 16.


Annual Report, Associated Charities, Memphis, 1919 Jan 2025

Annual Report, Associated Charities, Memphis, 1919

Documents

Eighth Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1918-1919.


Annual Report, Associated Charities, Memphis, 1921 Jan 2025

Annual Report, Associated Charities, Memphis, 1921

Documents

Tenth Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1920-1921.


Annual Report, Associated Charities, Memphis, 1915 Jan 2025

Annual Report, Associated Charities, Memphis, 1915

Documents

Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1914 September 1 - 1915 September 1.


Annual Report, Associated Charities, Memphis, 1920 Jan 2025

Annual Report, Associated Charities, Memphis, 1920

Documents

Annual Report of the Associated Charities, Memphis, TN. It covers the time period of 1919-1920.